CN109316668A - It is a kind of easily from the internal radiotherapy device taken out in vivo - Google Patents
It is a kind of easily from the internal radiotherapy device taken out in vivo Download PDFInfo
- Publication number
- CN109316668A CN109316668A CN201811119124.6A CN201811119124A CN109316668A CN 109316668 A CN109316668 A CN 109316668A CN 201811119124 A CN201811119124 A CN 201811119124A CN 109316668 A CN109316668 A CN 109316668A
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- Prior art keywords
- connecting rod
- radioactive source
- vivo
- taken out
- device taken
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1014—Intracavitary radiation therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1007—Arrangements or means for the introduction of sources into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1028—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy using radiation sources applied onto the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N2005/1019—Sources therefor
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Radiation-Therapy Devices (AREA)
Abstract
The invention discloses one kind easily from the internal radiotherapy device taken out in vivo, is to be repeated in be formed by fixedly connecting with medical material connecting rod and radioactive source, the quantity of connecting rod is 1 more than radioactive source.The invention has the benefit that easy to operate, operating time is short;It realizes accurate positioning of the radioactive source in tumour, avoids the variation for influencing source positions because of organ activity;Falling off or migrating for radioactive source is avoided, side effect, good effect are reduced;After treatment, taking-up radioactive source can be facilitated, noresidue reduces the unnecessary irradiation of normal tissue, reduces side reaction;It keeps organ complete and function perfects.
Description
Technical field
The invention belongs to the field of medical instrument technology, are related to one kind easily from the internal radiotherapy device taken out in vivo.
Background technique
Malignant tumour, which has become, a kind of seriously threatens human health and common multiple disease.Currently, radiotherapy becomes
One of the three big main means for treating tumour.When radiotherapy mainly penetrates tissue using ray, normal tissue and tumour
Cell controls difference biological respinse mechanism caused by radioactive ray the growth and proliferation for the treatment of tumour cell.With operative treatment
It is compared with chemotherapy, radiotherapy can retain the function of treated organ, and treatment side effect is small, can effectively ensure that patient is cured
Life quality afterwards.
Radioactive prospecting instrument tumour is subjected to internal radiotherapy, also known as brachytherapy is percutaneous or art in lead to
Implant needle or implanting device are crossed by a certain number of radioactive source implantation tumours position, the ray issued using radioactive source is for a long time to swollen
The irradiation of oncocyte, killing or kill tumour cell, to achieve the purpose that treatment.The treatment technology is widely using various
The implanted treatment of entity tumor, achieves good therapeutic effect.It is excellent that this method has that curative effect is high, easy to operate and wound is small etc.
Point.But there is also some disadvantages for this method (radioactivity Implantation in Treating), as influenced after (1) implantation because of organ activity
Source positions and arrangement cause dosage distribution to change, influence therapeutic effect;(2) falling off or migrate there are radioactive source;(3)
Radioactive source stays in the body, and is not easy to take out from internal after treatment, to patient at heart or body brings certain burden;(4) clinical
Operate relative complex, operating time is long.These disadvantages show in the treatment of head and neck neoplasm, superficial tumor and breast cancer etc.
Become apparent from.
Summary of the invention
The purpose of the present invention is overcoming the prior art, one kind is provided and is mainly used for treating hand, foot, ear, tongue, nose
The shallower tumour such as chamber, incidence, mammary gland, easy to operate, structure is simple, good effect, easily from the internal radiotherapy taken out in vivo
Device.
Technical solution of the present invention is summarized as follows:
It is a kind of easily from the internal radiotherapy device taken out in vivo, be repeated in solid with medical material connecting rod 1 and radioactive source 2
Surely it is formed by connecting, the quantity of connecting rod 1 is than radioactive source more than 21.
The length of medical material connecting rod 1 is 5mm~500mm, and the medical material connecting rod 1 is solid hopkinson bar or hollow
Bar, the diameter of solid hopkinson bar are 0.1mm~2mm, and the outer diameter of hollow stem is 0.1mm~2mm.
It is columned shape that the shape of radioactive source 2, which is spherical, cylindric or both ends centre hemispherical, connecting rod 1 with
The position that radioactive source 2 connects matches with the radioactive source end.
Medical material is gold, silver, platinum, tantalum, niobium, zirconium, medical stainless steel, medical titanium, medical titanium alloy, Co-Cr-Mo conjunction
Gold, gathers Co-Ni-Cr-Mo alloy, niti-shaped memorial alloy, polyether-polyurethane, polytetrafluoroethylene (PTFE), silicon rubber, polyester, nylon
Methyl methacrylate, polyvinyl chloride, polyethylene, polypropylene, polystyrene, polyvinyl alcohol, poly(aryl ether ketone) or nonabsorable seam
Zygonema.
The number of connecting rod 1 is 2-16.
It is fixedly connected as welding, is glued or rivets.
The end of connecting rod 1 and fixing clamp, snak link or button are flexibly connected.
The invention has the benefit that (1) is easy to operate, operating time is short;(2) realize that radioactive source is accurate in tumour
Positioning, avoids the variation that source positions are influenced because of organ activity;(3) falling off or migrating for radioactive source is avoided, is reduced secondary
Effect, good effect;(4) after treating, taking-up radioactive source can be facilitated, noresidue reduces the unnecessary irradiation of normal tissue, reduces
Side reaction;It keeps organ complete and function perfects.
Detailed description of the invention
Fig. 1 is a kind of the schematic diagram of the section structure that center line is easily crossed from the internal radiotherapy device taken out in vivo of the present invention.
Fig. 2 is snak link schematic diagram
Fig. 3 is fixing clamp schematic diagram.
Fig. 4 is present invention one kind easily from the implanting state schematic diagram of the internal radiotherapy device taken out in vivo.
Specific embodiment
The present invention will be further described below with reference to the drawings.
It is a kind of easily from the internal radiotherapy device (see Fig. 1) taken out in vivo, be repeated in medical material connecting rod 1 and putting
It penetrates source 2 to be formed by fixedly connecting, the quantity of connecting rod 1 is than radioactive source more than 21.
Connecting rod 1 is preferably solid hopkinson bar, and diameter is preferably 0.8mm, can also select the arbitrary number in 0.1mm~2mm, such as
0.1mm, 0.3mm, 0.5mm, 1.2mm, 2mm etc..
Hollow stem can also be selected, outer diameter is preferably 0.8mm, the arbitrary number in 0.1mm~2mm can also be selected, such as
0.1mm, 0.3mm, 0.5mm, 1.2mm, 2mm etc..
Length is preferably 15mm, can also select the arbitrary number of 5mm~500mm, such as 5mm, 10mm, 30mm, 100mm,
150mm, 300mm, 500mm etc..
The shape of radioactive source 2 be it is spherical, can also select cylindric or both ends centre hemispherical be columned shape
Shape, the end that connecting rod 1 is connect with radioactive source 2 match with the radioactive source end.
Medical material is preferably niti-shaped memorial alloy, and gold, silver, platinum, tantalum, niobium, zirconium, 316L can also be selected medical stainless
Steel, 304 medical stainless steels, commercial pure titanium, medical TC4 titanium alloy, Ti-15Mo titanium alloy, TNTZ alloy, Ti2448, food-grade
Polyether-polyurethane, food-grade polytetrafluoroethylene (PTFE), silicon rubber, polyester, nylon, food is grade polymethylmethacrylacontinuous, polyvinyl chloride,
Polyethylene, polypropylene, polystyrene, polyvinyl alcohol, poly(aryl ether ketone) or nonabsorable suture.
The number of connecting rod 1 is 2-16.
Connection preferred weld connection between connecting rod 1 and radioactive source 2, can also select splicing and riveting.
The end of connecting rod 1 and fixing clamp, snak link or button are flexibly connected.
Radioactive source 2 is iodine-125, palladium -103, Radium-224, cesium-131, Iridium-192 source, ytterbium -169, phosphorus -32 and Yttrium-90.It is preferred that
For iodine-125, palladium -103, Radium-224, cesium-131.
1 middle part of connecting rod is circle perpendicular to the section configuration of long axis, oval, rectangle or other geometry polygons, but
In view of the impression and applicability of patient, section of the present invention is preferably circular.
The shape of 1 end of connecting rod can be processed into different geometries, it is contemplated that the applicability present invention is processed as hemisphere
Shape.
The diameter of connecting rod 1 can be the same or different with the hemispheric diameter in end, it is contemplated that the impression of patient, this
It is preferably identical as the diameter of connecting rod to invent the hemispheric diameter in end.
The hemispherical of 1 end of connecting rod can be linked together with connecting rod by modes such as welding, riveting or splicing,
It can be overall processing.In view of applicability and operability, the present invention is overall processing, i.e., directly adds in the end of connecting rod
Work hemispherical.
The end (one end not being connected with radioactive source) of connecting rod 1 and fixing clamp, snak link or button are flexibly connected.
The fixing clamp being flexibly connected with the end of connecting rod 1, snak link or button are commercially available.Including different geometries,
In view of the applicability present invention uses snak link.
The operation that radioactive source is connect with connecting rod is as follows:
Radioactive source and connecting rod are welded together by welding.
It is a kind of easily from the use of the internal radiotherapy device (abbreviation radiotheraphy device) taken out in vivo (for treating hand, foot, ear
Piece, the shallower tumour such as tongue, nasal cavity, incidence, mammary gland):
Quantity and the position that radiotheraphy device is placed needed for determining according to patient tumors size, see Fig. 4, radiotheraphy device are placed in
In implant needle or implanting device, after passing through tumour and skin with implant needle or implanting device, radiotheraphy device is released with push rod, passes through pulling
The position of the connecting rod adjustment radioactive source of radiotheraphy device, extracts implant needle or implanting device out, with fixing clamp (be also possible to snak link or
Button) the exposed both ends in extracutaneous connecting rod 1 are fixed, carry out radiotherapy.After treatment end, the fixing clamp (bullet of one end is removed
Spring button or button), radiotheraphy device is pulled out from the other end.
The above content is illustrate the specific embodiment party, and it cannot be said that of the invention to what the present invention was done in conjunction with the embodiments
Formula is only limitted to these explanations.For general technical staff of the technical field of the invention, present inventive concept is not being departed from
Under the premise of, several simple deductions and transformation can also be made, all shall be regarded as belonging to protection scope of the present invention.
Claims (7)
1. one kind is easily from the internal radiotherapy device taken out in vivo, it is characterized in that be repeated in medical material connecting rod (1) and
Radioactive source (2) is formed by fixedly connecting, and the quantity of connecting rod (1) is than radioactive source more than 21.
2. one kind according to claim 1 is easily from the internal radiotherapy device taken out in vivo, it is characterized in that the medical material
Expect connecting rod (1) length be 5mm~500mm, the medical material connecting rod (1) be solid hopkinson bar or hollow stem, solid hopkinson bar
Diameter is 0.1mm~2mm, and the outer diameter of hollow stem is 0.1mm~2mm.
3. one kind according to claim 1 is easily from the internal radiotherapy device taken out in vivo, it is characterized in that the radioactive source
(2) shape is that spherical, cylindric or both ends centre hemispherical is columned shape, and connecting rod (1) and radioactive source (2) are even
The position connect matches with the radioactive source end.
4. one kind according to claim 1 is easily from the internal radiotherapy device taken out in vivo, it is characterized in that the medical material
Material is gold, silver, platinum, tantalum, niobium, zirconium, medical stainless steel, medical titanium, medical titanium alloy, Co-Cr-Mo alloy, Co-Ni-Cr-Mo conjunction
Gold, niti-shaped memorial alloy, polyether-polyurethane, polytetrafluoroethylene (PTFE), silicon rubber, polyester, nylon, polymethyl methacrylate,
Polyvinyl chloride, polyethylene, polypropylene, polystyrene, polyvinyl alcohol, poly(aryl ether ketone) or nonabsorable suture.
5. one kind according to claim 1 is easily from the internal radiotherapy device taken out in vivo, it is characterized in that the connecting rod
(1) number is 2-16.
6. the apparatus according to claim 1, it is characterized in that described is fixedly connected as welding, is glued or rivets.
7. device described in one of -6 according to claim 1, it is characterized in that end and fixing clamp in the connecting rod (1), bullet
Spring button or button are flexibly connected.
Priority Applications (1)
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CN201811119124.6A CN109316668A (en) | 2018-09-25 | 2018-09-25 | It is a kind of easily from the internal radiotherapy device taken out in vivo |
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CN201811119124.6A CN109316668A (en) | 2018-09-25 | 2018-09-25 | It is a kind of easily from the internal radiotherapy device taken out in vivo |
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CN201811119124.6A Pending CN109316668A (en) | 2018-09-25 | 2018-09-25 | It is a kind of easily from the internal radiotherapy device taken out in vivo |
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Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000009212A2 (en) * | 1998-08-13 | 2000-02-24 | Nycomed Amersham Plc | Apparatus and methods for radiotherapy |
CN1761500A (en) * | 2003-03-17 | 2006-04-19 | 医疗物理有限公司 | Products and methods for brachytherapy |
CN202724446U (en) * | 2012-03-16 | 2013-02-13 | 吴沛宏 | High flexibility radioactive particle |
CN103736201A (en) * | 2013-12-31 | 2014-04-23 | 原子高科股份有限公司 | Radioactive particle chain |
CN105920727A (en) * | 2016-04-11 | 2016-09-07 | 王娟 | Radioactive particle chain and use method thereof |
CN106823121A (en) * | 2017-01-24 | 2017-06-13 | 原子高科股份有限公司 | A kind of degradable radioactive particle chain with shape memory function |
-
2018
- 2018-09-25 CN CN201811119124.6A patent/CN109316668A/en active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000009212A2 (en) * | 1998-08-13 | 2000-02-24 | Nycomed Amersham Plc | Apparatus and methods for radiotherapy |
CN1761500A (en) * | 2003-03-17 | 2006-04-19 | 医疗物理有限公司 | Products and methods for brachytherapy |
CN202724446U (en) * | 2012-03-16 | 2013-02-13 | 吴沛宏 | High flexibility radioactive particle |
CN103736201A (en) * | 2013-12-31 | 2014-04-23 | 原子高科股份有限公司 | Radioactive particle chain |
CN105920727A (en) * | 2016-04-11 | 2016-09-07 | 王娟 | Radioactive particle chain and use method thereof |
CN106823121A (en) * | 2017-01-24 | 2017-06-13 | 原子高科股份有限公司 | A kind of degradable radioactive particle chain with shape memory function |
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Application publication date: 20190212 |