CN107569766A - A kind of radioactive particle support for cavity tumour Inner irradiation - Google Patents
A kind of radioactive particle support for cavity tumour Inner irradiation Download PDFInfo
- Publication number
- CN107569766A CN107569766A CN201710670471.7A CN201710670471A CN107569766A CN 107569766 A CN107569766 A CN 107569766A CN 201710670471 A CN201710670471 A CN 201710670471A CN 107569766 A CN107569766 A CN 107569766A
- Authority
- CN
- China
- Prior art keywords
- particle
- radioactive particle
- alloy tube
- tube wire
- opening
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002245 particle Substances 0.000 title claims abstract description 70
- 230000002285 radioactive effect Effects 0.000 title claims abstract description 47
- 206010028980 Neoplasm Diseases 0.000 title claims abstract description 32
- 229910045601 alloy Inorganic materials 0.000 claims abstract description 39
- 239000000956 alloy Substances 0.000 claims abstract description 39
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 6
- 229910001000 nickel titanium Inorganic materials 0.000 claims description 4
- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical compound [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 claims description 4
- OAICVXFJPJFONN-OUBTZVSYSA-N Phosphorus-32 Chemical compound [32P] OAICVXFJPJFONN-OUBTZVSYSA-N 0.000 claims description 3
- VWQVUPCCIRVNHF-OUBTZVSYSA-N Yttrium-90 Chemical compound [90Y] VWQVUPCCIRVNHF-OUBTZVSYSA-N 0.000 claims description 3
- TVFDJXOCXUVLDH-YPZZEJLDSA-N cesium-131 Chemical compound [131Cs] TVFDJXOCXUVLDH-YPZZEJLDSA-N 0.000 claims description 3
- 150000001879 copper Chemical class 0.000 claims description 3
- PCHJSUWPFVWCPO-OUBTZVSYSA-N gold-198 Chemical compound [198Au] PCHJSUWPFVWCPO-OUBTZVSYSA-N 0.000 claims description 3
- 229910052742 iron Inorganic materials 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- KDLHZDBZIXYQEI-OIOBTWANSA-N palladium-103 Chemical compound [103Pd] KDLHZDBZIXYQEI-OIOBTWANSA-N 0.000 claims description 3
- 230000000149 penetrating effect Effects 0.000 claims description 3
- 229940097886 phosphorus 32 Drugs 0.000 claims description 3
- NAWDYIZEMPQZHO-AHCXROLUSA-N ytterbium-169 Chemical compound [169Yb] NAWDYIZEMPQZHO-AHCXROLUSA-N 0.000 claims description 3
- 238000009954 braiding Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 4
- 238000010276 construction Methods 0.000 abstract description 3
- 238000004519 manufacturing process Methods 0.000 abstract description 3
- 230000005855 radiation Effects 0.000 abstract description 2
- 238000002560 therapeutic procedure Methods 0.000 abstract description 2
- 235000001674 Agaricus brunnescens Nutrition 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 206010004593 Bile duct cancer Diseases 0.000 description 1
- 208000017897 Carcinoma of esophagus Diseases 0.000 description 1
- 208000000461 Esophageal Neoplasms Diseases 0.000 description 1
- 208000026900 bile duct neoplasm Diseases 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000000686 essence Substances 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Landscapes
- Radiation-Therapy Devices (AREA)
Abstract
The invention discloses a kind of radioactive particle support for cavity tumour Inner irradiation, including it is provided with along long axis direction the alloy tube wire 3 of opening and weaves the rack body 1 and radioactive particle 2 that form, the radioactive particle 2 is arranged in the alloy tube wire 3 of opening.The present invention is simple in construction, simple for production, easy to use, can be prepared into different size and model, suitable for different tumor sizes, realize the conformal therapy of cavity tumour, so as to improve curative effect, lower the damage of normal tissue.Radioactive particle is stuck in or is bonded in securely the diverse location of the alloy tube wire of opening, reduces radioactive particle and comes off probability.Radiation shield of the alloy tube wire wall to radioactive particle is reduced, radioactivity utilization ratio is improved, reduces cost.
Description
Technical field
The invention belongs to medical instruments field, and in particular to a kind of radioactive particle branch for cavity tumour Inner irradiation
Frame.
Background technology
The problem of cavity cancer maximum is exactly to block, when that can not use operation or other means remove tumour, using radiotherapy energy
Effectively suppress the growth of tumour, but extracorporeal irradiation has the shortcomings of irradiation is discontinuous, radiological dose is big.At present, Medical rack has been
It is narrow through being widely used in clinical treatment cavity, common Medical rack uniquely rely on the support force of support in itself strut it is narrow
Cavity, certain mitigation is served, but as the probability of the growth ISR of tumour is larger.
In recent years, substantial amounts of clinical treatment proves et al. Ke radioactive particle such as125I etc. is to cancers such as cancer of the esophagus, cancer of bile ducts
Disease patient reaches good therapeutic effect, and over the course for the treatment of to the damage very little of the other tissues of patient.ZL03221951.2
Inner irradiation support is disclosed, radion is packed into the particle filling pipe being bundled on support by it, the advantages of the invention
It is：(1) particle filling pipe is provided with radion support, particle can be implanted in vivo with support.(2) radioactive source
Can irradiation tumour closely for a long time, to suppress its growth.Its shortcoming is：(1) for single support, particle filling pipe
Position is fixed, number is limited, and the lesions position of patient is different, size of tumor and different, the radioactivity grain of required placement
The position and number of son also differ.(2) particle filling pipe position protrudes, and local compression is heavier, easily causes local damage, goes out
Blood.(3) Nitinol filling pipe can mask a part of activity, the irradiation intensity of tumour can be weakened, so as to influence to treat
Effect.(4) preparation technology is complicated.
The content of the invention
The purpose of the present invention is overcome the deficiencies in the prior art, there is provided a kind of simple in construction, simple for production, implantation is convenient,
It is not easy a kind of radioactive particle support for cavity tumour Inner irradiation for causing local damage.
Technical scheme is summarized as follows：
A kind of radioactive particle support for cavity tumour Inner irradiation, including it is provided with along long axis direction the alloy of opening
Pipe silk 3 weaves the rack body 1 and radioactive particle 2 formed, and radioactive particle 2 is arranged in the alloy tube wire 3 of opening.
The shape of rack body 1 is selected from：Cylindrical shape, it is tubaeform, middle in cylinder both ends flare, spherical or mushroom
Shape.
The internal diameter of the alloy tube wire 3 of opening is 0.2~2mm；It is corresponding, the external diameter of radioactive particle 2 for 0.2~
2mm and length are 0.2~20mm, or the external diameter of radioactive particle 2 is slightly less than the internal diameter of alloy tube wire 3.
Radioactive particle is selected from：I-125 seeds, the particle of palladium -103, the particle of gold -198, cesium-131 particle, ytterbium -169
Son, Yttrium-90 particle and the particle of phosphorus -32.
The opening chord length of the alloy tube wire 3 of opening is the 1/4~1 of the alloy tube wire internal diameter of opening.
The material of the alloy tube wire 3 of opening is selected from：Nitinol, copper series alloy or iron-based alloy with Memorability.
The present invention is simple in construction, simple for production, easy to use, different size and model can be prepared into, suitable for difference
Tumor size, the conformal therapy of cavity tumour is realized, so as to improve curative effect, lower the damage of normal tissue.Radioactive particle
The diverse location of the alloy tube wire of opening is stuck in or be bonded in securely, radioactive particle is reduced and comes off probability.Reduce conjunction
Golden Guan Sibi improves radioactivity utilization ratio, reduces cost to the radiation shield of radioactive particle.
Brief description of the drawings
Fig. 1 is a kind of radioactive particle supporting structure schematic diagram for cavity tumour Inner irradiation of the invention.
Fig. 2 is Fig. 1 partial enlarged drawings.
Fig. 3 is the alloy tube wire profilograph of opening.
Fig. 4 is that radioactive particle is arranged on schematic perspective view in the alloy tube wire of opening.
Embodiment
The present invention is described further below in conjunction with the accompanying drawings.
A kind of radioactive particle support for cavity tumour Inner irradiation, is shown in Fig. 1, Fig. 2, Fig. 3 and Fig. 4, including along major axis
The alloy tube wire 3 that direction is provided with opening weaves the rack body 1 and radioactive particle 2 formed, and radioactive particle 2 is arranged on out
In the alloy tube wire 3 of mouth.
The shape of rack body 1 is selected from：Cylindrical shape, it is tubaeform, middle in cylinder both ends flare, spherical or mushroom
Shape.
Arbitrary Digit of the internal diameter of the alloy tube wire 3 of opening between 0.2mm~2mm, such as：0.2mm、0.3mm、0.5mm、
0.8mm, 1mm, 1.5mm or 2mm；It is corresponding, the Arbitrary Digit of the external diameter of radioactive particle 2 between 0.2mm~2mm, example
Such as：0.2mm, 0.3mm, 0.5mm, 0.8mm, 1mm, 1.5mm or 2mm；And radioactive particle length is between 0.2mm~20mm
Arbitrary Digit, such as：0.2mm, 0.3mm, 0.5mm, 0.8mm, 1mm, 1.5mm, 2mm, 5mm, 8mm, 10mm, 15mm or 20mm；Or put
The external diameter of penetrating property particle 2 is slightly less than the internal diameter of alloy tube wire 3.
Radioactive particle is selected from：I-125 seeds, the particle of palladium -103, the particle of gold -198, cesium-131 particle, ytterbium -169
Son, Yttrium-90 particle and the particle of phosphorus -32.
The opening chord length of the alloy tube wire 3 of opening is the 1/4,1/2,3/4 or 1 of the alloy tube wire internal diameter of opening, when for 1
When, radioactive particle is bonded on the alloy tube wire inwall of opening.
The material of the alloy tube wire 3 of opening is selected from：Nitinol, copper series alloy or iron-based alloy with Memorability.
A kind of radioactive particle support for cavity tumour Inner irradiation may be made as all size, select different quantity
Radioactive particle is distributed in the alloy tube wire of opening, and by card, or bonding, makes radioactive particle and the alloy tube wire of opening
It is combined together.
It is prepared by a kind of radioactive particle support for cavity tumour Inner irradiation：
Support is woven into by compiling tube apparatus with the alloy tube wire 3 of opening, the opening of the alloy tube wire of opening, will towards outside
Arrange and be fixed on alloy tube wire with the radioactive particle of pipe silk internal diameter same outer diameter.
A kind of use for cavity tumour Inner irradiation radioactive particle support：
(1) putting for cavity tumour Inner irradiation is determined by treatment planning systems according to the size and shape of cavity tumour
The specification that the shape of penetrating property particle support, size and radioactive particle species, quantity determine；
(2) radioactive particle support is placed by tumor locus by cavity bracket conveyer.
Above-mentioned embodiment is intended merely to explain and passes on the present invention to solve the problems, such as that current radion support is present
And the new technical scheme proposed, it is impossible to limited the scope of the invention with this, all Spirit Essences according to the present invention are done
Structure improve and modification, should all cover within the scope of the present invention.
Claims (6)
- A kind of 1. radioactive particle support for cavity tumour Inner irradiation, it is characterized in that including being provided with opening along long axis direction Alloy tube wire (3) the braiding rack body (1) and radioactive particle (2) that form, the radioactive particle (2) is arranged on opening Alloy tube wire (3) in.
- A kind of 2. radioactive particle support for cavity tumour Inner irradiation according to claim 1, it is characterized in that support Body (1) is shaped as cylindrical shape, is tubaeform, middle in cylinder both ends flare, spherical or mushroom-shaped.
- 3. the radioactive particle support according to claim 1 for cavity tumour Inner irradiation, it is characterized in that the opening The internal diameter of alloy tube wire (3) be 0.2~2mm；The external diameter of the radioactive particle (2) be 0.2~2mm and length be 0.2~ 20mm。
- 4. the radioactive particle support for cavity tumour Inner irradiation according to claim 1 or 3, it is characterized in that described put Penetrating property particle be I-125 seeds, the particle of palladium -103, the particle of gold -198, cesium-131 particle, the particle of ytterbium -169, Yttrium-90 particle and The particle of phosphorus -32.
- 5. the radioactive particle support for cavity tumour Inner irradiation according to claim 1 or 3, it is characterized in that described open The opening chord length of the alloy tube wire (3) of mouth is the 1/4~1 of the alloy tube wire internal diameter of opening.
- 6. the radioactive particle support for cavity tumour Inner irradiation according to claim 1 or 3, it is characterized in that described open The material of the alloy tube wire (3) of mouth is the Nitinol with Memorability, copper series alloy or iron-based alloy.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710670471.7A CN107569766A (en) | 2017-08-08 | 2017-08-08 | A kind of radioactive particle support for cavity tumour Inner irradiation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710670471.7A CN107569766A (en) | 2017-08-08 | 2017-08-08 | A kind of radioactive particle support for cavity tumour Inner irradiation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107569766A true CN107569766A (en) | 2018-01-12 |
Family
ID=61035611
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710670471.7A Pending CN107569766A (en) | 2017-08-08 | 2017-08-08 | A kind of radioactive particle support for cavity tumour Inner irradiation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107569766A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109011213A (en) * | 2018-08-17 | 2018-12-18 | 江苏莱福医疗器械科技有限公司 | A kind of radioactive particle automatic sequencing device |
| CN110215600A (en) * | 2019-05-27 | 2019-09-10 | 北京大学第三医院 | The implantation material of radion can be carried |
| CN113577525A (en) * | 2021-06-01 | 2021-11-02 | 中国人民解放军火箭军特色医学中心 | Conformal adjustable internal radioactive membranous stent for malignant tumor of human body cavity and organ |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101161297A (en) * | 2007-11-21 | 2008-04-16 | 李楠 | Medical tectorial membrane shaped radiation NiTi alloy endovascular stent |
| CN201798827U (en) * | 2010-09-28 | 2011-04-20 | 上海交通大学医学院附属瑞金医院卢湾分院 | Biliary tract internal exposure support |
| CN106974752A (en) * | 2017-04-06 | 2017-07-25 | 张西坤 | Spiral particle support |
| CN208927418U (en) * | 2017-08-08 | 2019-06-04 | 天津赛德医药研究院有限公司 | A kind of radioactive particle bracket for cavity tumour Inner irradiation |
-
2017
- 2017-08-08 CN CN201710670471.7A patent/CN107569766A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101161297A (en) * | 2007-11-21 | 2008-04-16 | 李楠 | Medical tectorial membrane shaped radiation NiTi alloy endovascular stent |
| CN201798827U (en) * | 2010-09-28 | 2011-04-20 | 上海交通大学医学院附属瑞金医院卢湾分院 | Biliary tract internal exposure support |
| CN106974752A (en) * | 2017-04-06 | 2017-07-25 | 张西坤 | Spiral particle support |
| CN208927418U (en) * | 2017-08-08 | 2019-06-04 | 天津赛德医药研究院有限公司 | A kind of radioactive particle bracket for cavity tumour Inner irradiation |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109011213A (en) * | 2018-08-17 | 2018-12-18 | 江苏莱福医疗器械科技有限公司 | A kind of radioactive particle automatic sequencing device |
| CN110215600A (en) * | 2019-05-27 | 2019-09-10 | 北京大学第三医院 | The implantation material of radion can be carried |
| CN113577525A (en) * | 2021-06-01 | 2021-11-02 | 中国人民解放军火箭军特色医学中心 | Conformal adjustable internal radioactive membranous stent for malignant tumor of human body cavity and organ |
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|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20180112 |