CN201798827U - Biliary tract internal exposure support - Google Patents

Biliary tract internal exposure support Download PDF

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Publication number
CN201798827U
CN201798827U CN2010205454224U CN201020545422U CN201798827U CN 201798827 U CN201798827 U CN 201798827U CN 2010205454224 U CN2010205454224 U CN 2010205454224U CN 201020545422 U CN201020545422 U CN 201020545422U CN 201798827 U CN201798827 U CN 201798827U
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China
Prior art keywords
radioactive particle
biliary tract
filling capsule
particle filling
main body
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Expired - Lifetime
Application number
CN2010205454224U
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Chinese (zh)
Inventor
王忠敏
陆健
潘长网
李玉茜
金富康
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Ruinjin Hospital Affiliated to Shanghai Jiaotong University School of Medicine Co Ltd Luwan Branch
Original Assignee
Micro Tech Nanjing Co Ltd
Ruinjin Hospital Affiliated to Shanghai Jiaotong University School of Medicine Co Ltd Luwan Branch
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Application filed by Micro Tech Nanjing Co Ltd, Ruinjin Hospital Affiliated to Shanghai Jiaotong University School of Medicine Co Ltd Luwan Branch filed Critical Micro Tech Nanjing Co Ltd
Priority to CN2010205454224U priority Critical patent/CN201798827U/en
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Publication of CN201798827U publication Critical patent/CN201798827U/en
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Abstract

The utility model relates to a biliary tract internal exposure support constituted by a radioactive particle filling bag (1) and a main frame (2). The radioactive particle filling bag (1) is fixedly disposed on the main frame (2), which is a cylindrical grid frame woven with nickel-titanium alloy wire. By using the utility model, the clinical difficulties can be solved, and the radioactive particle internal exposure and the metal support expansion drainage technology can be effectively combined together, thereby the utility model has advantages of novel, simple structure, micro-invasive operation, less pain of patients, good curative effect, less complication, and wide clinical application prospect.

Description

Biliary tract internal radiation support
Technical field
This utility model relates to a kind of medical apparatus and instruments, especially a kind of expansion and biliary tract rack for the treatment of of having concurrently, specifically a kind of biliary tract internal radiation support that is used for local targeting internal-radiation therapy of biliary tract and biliary tract stenosis expansion drain synchronous therapeutic.
Background technology
At present, malignant biliary obstruction many by constitutional cancer of biliary duct, hepatocarcinoma, carcinoma of head of pancreas, carcinoma of ampulla, carcinoma of gallbladder and other metastatic carcinomas to due to the hepatobiliary compressing.No matter be former or secondary, block and mostly occur in hepatic portal portion, also can be at the far-end bile duct.How this type of patient merges serious cholangitis on the jaundice basis, the state of an illness is dangerous, and the whole body situation is poor, it is most of because tumor has belonged to the high grade of malignancy of late period or tumor, or because of higher operation risk, and can not excision, need take non-surgical treatment to remove obstruction of biliary tract.Biliary tract rack is implanted advantages such as having the biliary drainage of recovery, need not carry drainage tube, wound is little, has become the important method of treatment malignant biliary obstruction.
By the percutaneous transhepatic puncture approach macro porous silica gel support was used for the narrow treatment of optimum hepatic duct from reports such as Cameron JL in 1976, biliary tract prosthesis is year surplus clinical application 30, become a kind of effect palliative therapy method preferably of alleviating stenosis of bile duct, have advantages such as wound is little, complication is few, determined curative effect, can remove patient's jaundice, improve overall health of patients, but the general operating period of plastics inner support is 3 months, can block above most of support after 6 months, need take out implant frame once more.
Along with the development of scope and interventional radiology, utilize the means treatment cancer of biliary duct of Wicresoft, become external drainage into interior drain, simple to operate, its life quality is better than the surgery by-pass operation.CH Carrasco in 1985 etc. are reported in the experimental research that dog has carried out the utilization of self-inflated stainless steel stent biliary tract on alone.Self-inflated metal biliary tract rack had been applied to clinical in 1988.China also last century the nineties carry out the biliary tract rack implantation gradually.Because the self-inflated nitinol alloy wire has advantages such as shape memory characteristic, super-elasticity, now has been widely used in clinical.Metal rack biliary drainage art wound is little, and early complication is few, and operative mortality is low, and internal metal rack can arrive original diameter by self expandable after inserting narrow biliary tract, and narrow tube wall is produced the expansionary force that continues, and keeps the stable of support.This technology has become one of important method of treatment biliary tract stenosis at present, and especially for pernicious obstruction of biliary tract, its effect can reach the surgical operation level.
Use of metal stents in treatment is a kind of better method for the treatment of malignant biliary obstruction at present, but along with The application of new technique, the application of present biliary metallic stents has had certain limitation, only has the supporting drainage effect as existing support, but tumor tissues is not had therapeutical effect, so influenced the late result of malignant biliary obstruction.Therefore, if in the support expansion, can carry out the local internal-radiation therapy of targeting, can lower the toxic and side effects of whole body chemicotherapy, can realize that again the targeting internal radiation suppresses the growth of tumor thing, can improve biliary tract rack patency rate and patient's survival rate, biliary tract rack and internal radiation are had complementary advantages.
Conventional metal biliary tract rack is because the function that its body does not have to carry radioactive particle, so only can expand drain to stenosis of bile duct merely, as the method for palliative treatment, combine synchronously and implant and general supporting structure also can't be generally diameter the radioactive particle of 0.8 mm and rack body.
Summary of the invention
The purpose of this utility model is at existing biliary tract rack function singleness, can't realize expanding and treating the purpose of carrying out synchronously, designs a kind of biliary tract internal radiation support that can realize the expansion drain of local internal-radiation therapy and narrow positions simultaneously.
The technical solution of the utility model is:
A kind of biliary tract internal radiation support is characterized in that it mainly is made of radioactive particle filling capsule 1 and main body framework 2 two parts, and radioactive particle filling capsule 1 is fixed on the main body framework 2, and main body framework 2 is the cylindrical mesh skeletons that formed by the nitinol alloy wire braiding.
Described radioactive particle filling capsule 1 is tubular structure, spring tubular structure or bag shaped structure.
When described radioactive particle filling capsule 1 be tubular structure, its internal diameter matched with the particle external diameter that is loaded, and its end is provided with the opening that confession radioactive particle 3 is packed into, and the other end is enclosuring structure or the opening diameter hatch frame less than radioactive particle 3.
When described radioactive particle filling capsule 1 be the spring tubular structure, its internal diameter matched with the particle external diameter that is loaded, and the other end of bourdon tube is ringlet closing in structure or by wearing in the bourdon tube end thread to dwindle inner end diameter.
Described radioactive particle filling capsule 1 is single capsule structure or long tubular structure, loads the radion 3 more than two in the radion filling capsule of long tubular structure simultaneously.
Described radioactive particle filling capsule 1 distributes or asymmetric distribution along the arrangement of branches such as circumference, the rhombus of main body framework 2.
The inner surface of described main body framework 2 and/or outer surface can be provided with the overlay film layer, and as overlay film, then described overlay film layer is the materials such as medical grade silicon rubber, expanded PTFE or polyurethane with good biocompatibility.
One end of described main body framework 2 and/or two ends are horn mouth, ball mouth or rim of a cup.
The beneficial effects of the utility model are:
The radioactive particle filling capsule and the rack body skeleton of biliary tract internal radiation support of the present utility model are combined to form whole the use, the radioactive particle of packing in radioactive particle filling capsule inside, be implanted to the tumor locus of stenosis of bile duct then with rack body, stricture dilation drain and internal-radiation therapy are carried out in this position.
This utility model has solved a clinical difficult problem, and drainage technology is effective combines with the expansion of radioactive particle internal radiation and metal rack, has novelty simple in structure, Wicresoft's operation, risk is low, patient is painful little, good effect, the advantage that complication is few has boundless potential applicability in clinical practice.
This utility model loads capsule with radioactive particle and becomes as a whole with holder combination, thereby the less inserter of can packing into satisfies the requirement of current armarium Wicresoft operation, can once perform the operation and finish, convenient, the Wicresoft of operation technique, and risk is low, painful little, the surgery cost of patient also can effectively reduce.The biliary tract rack that radioactive particle is carried in feasible implantation becomes possibility, and risk is low, and patient's misery is little;
The design of syndeton of the present utility model and radioactive particle filling capsule, but the supplier just the doctor in operating process, load radioactive particle, thereby alleviate doctor's suffered radiation in operation process.
Radioactive particle filling capsule of the present utility model can carry out different arranging to radioactive particle with the sick position of change targetedly according to doctor's clinical requirement, thereby satisfy the tumor of different parts is carried out internal-radiation therapy, reduce damage simultaneously normal surrounding tissue.
Description of drawings
Fig. 1 is a structural representation of the present utility model.
Fig. 2 is the structural representation of radioactive particle filling capsule of the present utility model (spring tubulose list capsule).
Fig. 3 is the structural representation of radioactive particle filling capsule of the present utility model (spring pipe range tubular).
Fig. 4 is the structural representation of radioactive particle filling capsule of the present utility model (tubulose list capsule).
Fig. 5 is the structural representation of radion filling capsule of the present utility model (the long tubular of tubing).
Fig. 6 is the structural representation of rack body skeleton of the present utility model.
The specific embodiment
Below in conjunction with drawings and Examples this utility model is further described.
Embodiment one.
Shown in Fig. 1,2,3,6.
A kind of biliary tract internal radiation support, mainly form by radioactive particle filling capsule 1 and rack body skeleton 2, as shown in Figure 1, wherein radioactive particle filling capsule 1 can adopt the helical spring tubular construction that is formed by the nitinol alloy wire coiling shown in Fig. 2,3, the radioactive particle filling capsule 1 of Fig. 2 is used to adorn stifled simple grain radioactive particle 3, radioactive particle filling capsule 1 shown in Figure 3 can load many radioactive particles 3, and radioactive particle filling capsule 1 can be fixed on rack body skeleton 2 outer surfaces by modes such as stitching, bonding, bindings.Can install and fix one or more radioactive particle filling capsules 1 on each main body framework 2, uniform distribution or asymmetric distribution are fixed on the surface of rack body skeleton 2 as requested, be used to load radioactive particle filling capsule 1 predetermined fixed of radioactive particle 3 in main body framework 2, by operative doctor radioactive particle 3 is packed into from the upper end again before the use, the upper end open internal diameter of spring tubulose radioactive particle filling capsule 1 should match with the external diameter of radioactive particle 3, the lower end of bourdon tube can adopt the mode of closing in or wrapping wire to reduce its internal diameter, skid off with the radioactive particle that prevents to pack into, the main body framework 2 of support can form cylindrical mesh skeleton (as shown in Figure 6) by the nitinol alloy wire braiding, the both ends or one end of main body framework also can be horn mouth as required in case of necessity, ball mouth or rim of a cup structure can install end cap additional on the end of packing into of radioactive particle filling capsule 1, the employing plug seals or utilizes instrument to close up.The inner surface of main body framework 2 and/or outer surface can be provided with the overlay film layer also can not establish the overlay film layer, and as the need overlay film, then described overlay film layer is the materials such as medical grade silicon rubber, expanded PTFE or polyurethane with good biocompatibility.
During use, doctor's radioactive particle 3 of at first in radioactive particle filling capsule 1, packing into, radioactive particle 3 can be selected 103Pd, 60Co, 199Au, 192Ir, 125Medical radioactive material commonly used such as I, and then the support integral body that will install radioactive particle 3 reloads in the inserter, at the auxiliary release support down of seal wire guiding or endoscope, because the shape memory characteristic of Nitinol, support accurately is fixed in the stenosis of bile duct place, carry out radiotherapy thereby carry 3 pairs of tumors of radioactive particle, narrow also being strutted by the support expansion herein keeps drain unobstructed simultaneously.
Embodiment two.
Shown in Fig. 1,4,6.
A kind of biliary tract internal radiation support, it includes radioactive particle filling capsule 1 and rack body skeleton 2 is formed (as shown in Figure 1), mesh skeleton 2(is cylindrical) and radioactive particle filling capsule 1 can link together by modes such as stitching, bonding, bindings, radioactive particle filling capsule 1 is made up of medical high polymer tubing or medical metal tubing, and end opening other end sealing is used to pack into the single capsule structure of radioactive particle 3(as shown in Figure 4 on the tubing).Can install and fix one or more radioactive particle filling capsules 1 on each main body framework 2, uniform distribution or asymmetric distribution are fixed on the surface of rack body skeleton 2 as requested.Be used to load radioactive particle filling capsule 1 predetermined fixed of radioactive particle 3 in main body framework 2, by operative doctor radioactive particle 3 is packed into from the upper end again before the use, the upper end open lower end closed of radioactive particle filling capsule 1 or opening less than the external diameter of radioactive particle 3 in case on-slip go out, the main body framework 2 of support can form cylindrical mesh skeleton (as shown in Figure 6) by the nitinol alloy wire braiding, the both ends or one end of main body framework also can be horn mouth as required in case of necessity, ball mouth or rim of a cup structure can install end cap additional on the end of packing into of radioactive particle filling capsule 1, the employing plug seals or utilizes instrument to close up.The inner surface of main body framework 2 and/or outer surface can be provided with the overlay film layer also can not establish the overlay film layer, and as the need overlay film, then described overlay film layer is the materials such as medical grade silicon rubber, expanded PTFE or polyurethane with good biocompatibility.
During use, the doctor fills radioactive particle 3 for 1 li at particle filling capsule in advance, and radioactive particle 3 can be selected 103Pd, 60Co, 199Au, 192Ir, 125Medical radioactive material commonly used such as I, and then the rack body skeleton 2 that will carry radioactive particle filling capsule 1 and install radioactive particle 3 reloads in the inserter, at the auxiliary release support down of seal wire guiding or endoscope, and then at the auxiliary release support down of seal wire guiding or endoscope, because the shape memory characteristic of Nitinol, support is implanted in the stenosis of bile duct place, carry out radiotherapy thereby carry 3 pairs of tumors of radioactive particle, simultaneously herein narrow also strutted by the support expansion and keeps drain unobstructed.
Embodiment three.
Shown in Fig. 1,5,6.
A kind of biliary tract internal radiation support, it includes radioactive particle filling capsule 1 and rack body skeleton 2 is formed (as shown in Figure 1), cylindrical mesh skeleton 2 and radioactive particle filling capsule 1 link together by modes such as stitching, bondings, the long tubular that radioactive particle filling capsule 1 is made by medical film material forms, and each long tubular radioactive particle filling capsule 1 can load many radioactive particle 3(as shown in Figure 5).Can install and fix one or more radioactive particle filling capsules 1 on each main body framework 2, uniform distribution or asymmetric distribution are fixed on the surface of rack body skeleton 2 as requested.Be used to load radioactive particle filling capsule 1 predetermined fixed of radioactive particle 3 in main body framework 2, by operative doctor radioactive particle 3 is packed into from the upper end again before the use, the upper end open lower end closed of radioactive particle filling capsule 1 or opening less than the external diameter of radioactive particle 3 in case on-slip go out, the main body framework 2 of support can form cylindrical mesh skeleton (as shown in Figure 6) by the nitinol alloy wire braiding, the both ends or one end of main body framework also can be horn mouth as required in case of necessity, ball mouth or rim of a cup structure can install end cap additional on the end of packing into of radioactive particle filling capsule 1, the employing plug seals or utilizes instrument to close up.The inner surface of main body framework 2 and/or outer surface can be provided with the overlay film layer also can not establish the overlay film layer, and as the need overlay film, then described overlay film layer is the materials such as medical grade silicon rubber, expanded PTFE or polyurethane with good biocompatibility.
During use, the doctor at first packs radion 3 in the long tubular particle filling capsule of being made by medical film material 1, and radioactive particle 3 can be selected 103Pd, 60Co, 199Au, 192Ir, 125Medical radioactive material commonly used such as I, and then the rack body skeleton 2 that will carry radioactive particle filling capsule 1 and install radioactive particle 3 is packed in the inserter, at the auxiliary release support down of seal wire guiding or endoscope, because the shape memory characteristic of Nitinol, support accurately is fixed in the stenosis of bile duct place, carry out internal-radiation therapy thereby carry 3 pairs of tumors of radioactive particle, simultaneously herein narrow also strutted by the support expansion and keeps drain unobstructed.
Embodiment four.
The difference of present embodiment and embodiment one, two, three is that described radioactive particle filling capsule 1 is the bag shaped structure by the flexible medical material manufacture.
This utility model does not relate to the part prior art that maybe can adopt all same as the prior art to be realized.

Claims (8)

1. biliary tract internal radiation support, it is characterized in that it mainly is made of radioactive particle filling capsule (1) and main body framework (2) two parts, radioactive particle filling capsule (1) is fixed on the main body framework (2), and main body framework (2) is the cylindrical mesh skeleton that is formed by the nitinol alloy wire braiding.
2. biliary tract internal radiation support according to claim 1 is characterized in that described radioactive particle filling capsule (1) is tubular structure, spring tubular structure or bag shaped structure.
3. biliary tract internal radiation support according to claim 1 and 2, when it is characterized in that described radioactive particle filling capsule (1) for tubular structure, its internal diameter matches with the particle external diameter that is loaded, its end is provided with for radioactive particle (3) opening of packing into, and the other end is enclosuring structure or the opening diameter hatch frame less than radioactive particle (3).
4. biliary tract internal radiation support according to claim 1 and 2, when it is characterized in that described radioactive particle filling capsule (1) for the spring tubular structure, its internal diameter and the particle external diameter that is loaded match, and the other end of bourdon tube is ringlet closing in structure or by wearing silk in the bourdon tube end to dwindle inner end diameter.
5. biliary tract internal radiation support according to claim 1 is characterized in that described radioactive particle filling capsule (1) is single capsule structure or long tubular structure, loads the radion (3) more than two in the radion filling capsule of long tubular structure simultaneously.
6. biliary tract internal radiation support according to claim 1 is characterized in that described radioactive particle filling capsule (1) distributes or asymmetric distribution along the arrangement of branches such as circumference, the rhombus of main body framework (2).
7. biliary tract internal radiation support according to claim 1 is characterized in that the inner surface of described main body framework (2) and/or outer surface can be provided with the overlay film layer.
8. biliary tract internal radiation support according to claim 1 is characterized in that an end of described main body framework (2) and/or two ends are horn mouth, ball mouth or rim of a cup.
CN2010205454224U 2010-09-28 2010-09-28 Biliary tract internal exposure support Expired - Lifetime CN201798827U (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102335052A (en) * 2011-07-15 2012-02-01 南京微创医学科技有限公司 Anti-restenosis digestive tract stent
CN104353189A (en) * 2014-11-07 2015-02-18 滕皋军 Three-dimensional precise intraluminal radiation therapy method and system for cancer treatment
CN105030394A (en) * 2015-07-24 2015-11-11 南京微创医学科技有限公司 Device capable of carrying internal irradiation particles and manufacturing die and method of die
CN106422039A (en) * 2015-08-13 2017-02-22 上海微创医疗器械(集团)有限公司 Drug delivery device and manufacturing method thereof
CN106552317A (en) * 2016-11-23 2017-04-05 许荣德 A kind of radion carrying device
CN107212953A (en) * 2017-05-04 2017-09-29 郑州大学第附属医院 A kind of biliary tract radiation treatment stent
CN107569766A (en) * 2017-08-08 2018-01-12 天津赛德医药研究院有限公司 A kind of radioactive particle support for cavity tumour Inner irradiation
CN110314274A (en) * 2019-06-27 2019-10-11 原子高科股份有限公司 A kind of sacculus carrying radioactive particle

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102335052A (en) * 2011-07-15 2012-02-01 南京微创医学科技有限公司 Anti-restenosis digestive tract stent
CN104353189A (en) * 2014-11-07 2015-02-18 滕皋军 Three-dimensional precise intraluminal radiation therapy method and system for cancer treatment
CN105030394A (en) * 2015-07-24 2015-11-11 南京微创医学科技有限公司 Device capable of carrying internal irradiation particles and manufacturing die and method of die
CN106422039A (en) * 2015-08-13 2017-02-22 上海微创医疗器械(集团)有限公司 Drug delivery device and manufacturing method thereof
CN106552317A (en) * 2016-11-23 2017-04-05 许荣德 A kind of radion carrying device
CN107212953A (en) * 2017-05-04 2017-09-29 郑州大学第附属医院 A kind of biliary tract radiation treatment stent
CN107569766A (en) * 2017-08-08 2018-01-12 天津赛德医药研究院有限公司 A kind of radioactive particle support for cavity tumour Inner irradiation
CN110314274A (en) * 2019-06-27 2019-10-11 原子高科股份有限公司 A kind of sacculus carrying radioactive particle

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C14 Grant of patent or utility model
GR01 Patent grant
C56 Change in the name or address of the patentee
CP01 Change in the name or title of a patent holder

Address after: 200020 No. 149 South Chongqing Road, Shanghai, Luwan District

Patentee after: Luwan Branch of Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine

Patentee after: MICRO-TECH (NANJING) CO., LTD.

Address before: 200020 No. 149 South Chongqing Road, Shanghai, Luwan District

Patentee before: Luwan Branch of Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine

Patentee before: Nanjing Micro-Tech Co., Ltd.

TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20180510

Address after: 200020 Chongqing South Road, Luwan District, Luwan District, Shanghai

Patentee after: Luwan Branch of Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine

Address before: 200020 Chongqing South Road, Luwan District, Luwan District, Shanghai

Co-patentee before: Micro-Tech (Nanjing) Co., Ltd.

Patentee before: Luwan Branch of Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine

CX01 Expiry of patent term
CX01 Expiry of patent term

Granted publication date: 20110420