CN110314274A - A kind of sacculus carrying radioactive particle - Google Patents
A kind of sacculus carrying radioactive particle Download PDFInfo
- Publication number
- CN110314274A CN110314274A CN201910570998.1A CN201910570998A CN110314274A CN 110314274 A CN110314274 A CN 110314274A CN 201910570998 A CN201910570998 A CN 201910570998A CN 110314274 A CN110314274 A CN 110314274A
- Authority
- CN
- China
- Prior art keywords
- sacculus
- radioactive particle
- carrying
- particle
- radioactive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 230000002285 radioactive effect Effects 0.000 title claims abstract description 91
- 239000002245 particle Substances 0.000 title claims abstract description 87
- 230000003902 lesion Effects 0.000 claims abstract description 21
- 210000001835 viscera Anatomy 0.000 claims abstract description 12
- 238000000034 method Methods 0.000 claims abstract description 11
- 208000005189 Embolism Diseases 0.000 claims abstract description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 4
- 239000000463 material Substances 0.000 claims description 12
- 238000002513 implantation Methods 0.000 claims description 10
- 230000001225 therapeutic effect Effects 0.000 claims description 9
- 238000009826 distribution Methods 0.000 claims description 7
- 230000005855 radiation Effects 0.000 claims description 6
- 241000894007 species Species 0.000 claims description 6
- 239000002775 capsule Substances 0.000 claims description 5
- 210000004881 tumor cell Anatomy 0.000 claims description 5
- 238000004519 manufacturing process Methods 0.000 claims description 4
- 210000003445 biliary tract Anatomy 0.000 claims description 3
- 239000013013 elastic material Substances 0.000 claims description 3
- 238000007912 intraperitoneal administration Methods 0.000 claims description 3
- 210000003708 urethra Anatomy 0.000 claims description 3
- 239000008280 blood Substances 0.000 claims description 2
- 210000004369 blood Anatomy 0.000 claims description 2
- 210000005077 saccule Anatomy 0.000 claims description 2
- 230000029087 digestion Effects 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000007943 implant Substances 0.000 abstract description 2
- 230000008569 process Effects 0.000 abstract description 2
- 238000001356 surgical procedure Methods 0.000 abstract description 2
- 210000001519 tissue Anatomy 0.000 description 5
- 206010028980 Neoplasm Diseases 0.000 description 4
- 238000006073 displacement reaction Methods 0.000 description 4
- 239000000853 adhesive Substances 0.000 description 3
- 230000001070 adhesive effect Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 231100000518 lethal Toxicity 0.000 description 2
- 230000001665 lethal effect Effects 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 230000035790 physiological processes and functions Effects 0.000 description 2
- 241000235503 Glomus Species 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000002648 combination therapy Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 238000010894 electron beam technology Methods 0.000 description 1
- 210000004907 gland Anatomy 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 210000005170 neoplastic cell Anatomy 0.000 description 1
- 210000004940 nucleus Anatomy 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 239000000941 radioactive substance Substances 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000011287 therapeutic dose Methods 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 210000004291 uterus Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1002—Intraluminal radiation therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1007—Arrangements or means for the introduction of sources into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1014—Intracavitary radiation therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1028—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy using radiation sources applied onto the body
Abstract
The invention discloses a kind of sacculus for carrying radioactive particle, sacculus is the sacculus used in body cavities or internal organs, it is implanted into Shi Weiwei expanded state, the balloon dilatation after the air of certain pressure or water are full, make balloon wall close to lesions position, fixed, support is played, expands, filling, be isolated, the function of embolism body cavities and internal organs, sacculus inner surface carries radioactive particle, and there is protrusion in sacculus outer surface.Sacculus provided by the present invention can carry out the close-range treatment of radioactive particle, simplify the implant surgery process of radioactive particle, saved operation cost, improve the safety for the treatment of.
Description
Technical field
The present invention relates to a kind of radioactivity close-range treatment fixture technology fields, and in particular to a kind of carrying radioactive particle
Sacculus.
Background technique
Malignant tumour is always to threaten the major disease of human health, closely control between tissue using radioactive particle
Treating tumour is the new technology that recent decades grow up.Radioactive particle is a kind of small radioactive sources, and the radioactive source is radioactivity
Isotope is in titanium tube, and both ends laser or electron beam technology weld to form sealed source, and size is generally outer diameter 0.8mm,
Length is 4.5mm.The common nucleic of radioactive particle has192Ir、198Au、169Y、131Cs、103Pd and125I etc., especially103Pd
With125I.Radioactive particle is implanted directly into lesion by close-range treatment, and short distance prolonged exposure destroys the DNA double of neoplastic cell nuclei
Key, lethal or sub- lethal tumor cell, makes it lose replication capacity, to reach therapeutic purposes, while isotope ray used
Energy is lower, and ray can effectively be avoided to damage normal tissue on the way in irradiation.
But, the entity being mainly used for radioactive particle suitable for radioactive prospecting instrument operation at present clinically
Tumor, and for the important organ, body of gland, cavity position of some unsuitable punctures, because radioactive particle can not be in lesions position
It is fixed, it is not just available radioactive particle and carries out the organ in close-range treatment, especially human body with larger cavity, such as stomach
The internal organs position such as portion, uterus, lesions position are located on cavity wall, and to carry out the treatment of radioactive particle at this position, simultaneously
The normal physiological function of internal organs can't be influenced, almost becomes impossible mission, this seriously hinders radioactivity grain
The application range of son.
Chinese patent " tumor by local comprehensive treatment and device " (publication number: CN 1537646A, publication date: 2004
On October 20, in) a kind of a variety of combination therapy means for being directed to lesions position based on air bag are provided, which use liquid
Body radioactive source perfusion balloon catheter is used for the radioactivity close-range treatment of tumour.But this mode be generally only suitable for it is interim short-term
Treatment, long-term or permanent sacculus implanted treatment can greatly increase the risk of sacculus rupture liquid radioactive source leakage, and liquid
Body radioactive source is difficult to realize the accurate effective distribution of radioactive dosage, and most radioactive ray therapeutic dose is present in ball
Intracapsular portion is absorbed by normal tissue.
Summary of the invention
In view of the deficiencies in the prior art, the purpose of the present invention is to provide a kind of balls for carrying radioactive particle
Capsule, allows the close-range treatment for having the internal organs of larger cavity body structure to carry out radioactive particle in human body, extends radioactivity grain
The close-range treatment application range of son.
To achieve the above object, The technical solution adopted by the invention is as follows:
A kind of sacculus carrying radioactive particle, the sacculus are the sacculus used in body cavities or internal organs, when implantation
For non-expanded state, the balloon dilatation after the air of certain pressure or water are full, play fixed, support, expand, filling, every
From, the function of embolism body cavities and internal organs, make balloon wall close to lesions position, sacculus inner surface carries radioactive particle,
There is protrusion in sacculus outer surface.
Further, the sacculus is made of medical elastic material, and same as the sacculus material of the protrusion use is made,
Or it is made using other biological compatibility material.
Further, the sacculus is spherical, stick or other are adapted to the special shape of implantation position.
Further, the sacculus is sacculus in alimentary canal, uterine cavity sacculus, intravaginal sacculus, biliary tract sacculus, glomus
One of capsule, intraperitoneal sacculus, urethra sacculus.
Further, the carrying method is the inner surface that radioactive particle is adhered to balloon wall with adhesive.
Further, the carrying method is the card slot in sacculus inner surface production radioactive particle, will radiation when use
Property particle be inserted into card slot.
Further, the radioactive particle is dispersed evenly to entire sacculus inner surface.
Further, it is distributed according to specific tumour cell, by radioactive particle integrated distribution in close to lesions position
Sacculus inner surface, accurately adjusting balloon position in implantation makes radioactive particle close to lesions position.
Further, the species type of the radioactive particle is192Ir、198Au、169Y、131Cs、103Pd and125One kind of I
Or it is a variety of.
Further, the sacculus for carrying radioactive particle takes out after completing therapeutic purposes or is not influencing human body just
It is chronically implanted in the case where normal function.
The beneficial effects of the present invention are:
1, the use scope for extending radioactive particle can not pass through the disease of puncture means immobilization of radioactive particle to some
Radioactive particle close to lesion and is played low coverage by mechanisms such as the fixation of sacculus, support, expansion, fillings by stove position
From therapeutic effect；
2, the protrusion of balloon surface can fix the balloon position after expanding, and radiate the radioactive particle of sacculus inner surface
Dosage distribution is fixed, and is reached the treatment to lesions position and is reduced the influence of normal tissue to greatest extent；
3, without puncturing to lesions position, radioactive particle is positioned at lesion portion merely by sacculus is full
Position, on the normal physiological function of the tissue of lesions position and internal organs substantially without influence；
4, the implant surgery process of radioactive particle is simplified, the sacculus of more radioactive particles of a carrying is implanted into and reaches
Operation can be completed to full stationary state and the operation of existing clinical radiation seeds implanted is needed through puncture means by grain
The mode of implantation radiation particle is compared, and operating time is greatly saved and reduces the agent that medical staff receives radioactive radiation
Amount can also reduce financial burden and operation wound that operation cost mitigates patient；
5, Therapeutic safety is high, even if sacculus ruptures after the implantation, radioactive particle migration will not occur, less
The diffusion of radioactive substance can occur.
Detailed description of the invention
Fig. 1 is the diagrammatic cross-section of the sacculus of the carrying radioactive particle of the embodiment of the present invention one；
Fig. 2 is the diagrammatic cross-section of the sacculus of the carrying radioactive particle of the embodiment of the present invention two；
Fig. 3 is the diagrammatic cross-section of the sacculus of the carrying radioactive particle of the embodiment of the present invention three；
Fig. 4 is the diagrammatic cross-section of the sacculus of the carrying radioactive particle of the embodiment of the present invention four；
Wherein:
1- sacculus；2- radioactive particle；3- is close to the region of lesions position；4- card slot；5- protrusion.
Specific embodiment
The present invention is described in further detail with specific embodiment with reference to the accompanying drawings of the specification.
Sacculus 1 is the sacculus used in body cavities or internal organs, is implanted into Shi Weiwei expanded state, the air through certain pressure
Or the full rear balloon dilatation of water, fixed, support is played, expands, filling, be isolated, the function of embolism body cavities and internal organs, is made
Balloon wall is made close to lesions position, sacculus of medical elastic material, including but not limited to sacculus in alimentary canal, uterine cavity ball
Capsule, intravaginal sacculus, biliary tract sacculus, blood saccule, intraperitoneal sacculus, urethra sacculus.
The sacculus can be spherical, stick or other are adapted to the special shape of implantation position；Outside the sacculus
Surface is equipped with protrusion；The inner surface of the sacculus carries radioactive particle.
Embodiment one:
As shown in Figure 1, the method that sacculus 1 carries radioactive particle is that radioactive particle 2 is adhered to sacculus with adhesive
The inner surface of wall, radioactive particle 2 intersperse among entire sacculus inner surface.The outer surface of the sacculus is equipped with protrusion 5, the protrusion
5 uses material identical with sacculus is made, or other biological compatibility material is used alone and is made, after balloon dilatation, protrusion 5
Sacculus can be preferably fixed on treatment position, sacculus is prevented to be subjected to displacement.The sacculus for carrying radioactive particle can be complete
It at being taken out after therapeutic purposes, can also be chronically implanted in the case where not influencing human normal function, the sacculus after taking-up can be with
It is re-used after replacement radioactive particle.The species type of radioactive particle includes192Ir、198Au、169Y、131Cs、103Pd
With125At least one of I.
Embodiment two:
As shown in Fig. 2, the method that sacculus 1 carries radioactive particle is that radioactive particle 2 is adhered to sacculus with adhesive
The inner surface of wall.Meanwhile being distributed according to specific tumour cell, by 2 integrated distribution of radioactive particle in close to lesions position
Region 3, accurately adjusting balloon position in implantation makes radioactive particle 2 close to lesions position.The outer surface of the sacculus is equipped with
Protrusion 5, raised 5 use material identical with sacculus is made, or exclusive use other biological compatibility material is made, ball
After capsule expands, sacculus can be preferably fixed on treatment position by protrusion 5, and sacculus is prevented to be subjected to displacement.Carry radioactive particle
Sacculus can be taken out after completing therapeutic purposes, can also be chronically implanted, take in the case where not influencing human normal function
Sacculus after out re-uses after can replacing radioactive particle.The species type of radioactive particle includes192Ir、198Au、169Y、131Cs、103Pd and125At least one of I.
Embodiment three:
As shown in figure 3, the method that sacculus 1 carries radioactive particle is the card slot in sacculus inner surface production radioactive particle
4, radioactive particle is inserted into card slot 4 when use.Card slot 4 is dispersed evenly to entire sacculus inner surface.The outer surface of the sacculus
Equipped with protrusion 5, raised 5 use material identical with sacculus is made, or exclusive use other biological compatibility material system
At after balloon dilatation, sacculus can be preferably fixed on treatment position by protrusion 5, and sacculus is prevented to be subjected to displacement.Carry radioactivity
The sacculus of particle can take out after completing therapeutic purposes, can also plant for a long time in the case where not influencing human normal function
Enter, the sacculus after taking-up re-uses after can replacing radioactive particle.The species type of radioactive particle includes192Ir、198Au、169Y、131Cs、103Pd and125At least one of I.
Example IV:
As shown in figure 4, the method that sacculus 1 carries radioactive particle is the card slot in sacculus inner surface production radioactive particle
4, radioactive particle is inserted into card slot 4 when use.It is distributed according to specific tumour cell, by 4 integrated distribution of card slot in close to disease
The region 3 at stove position, accurately adjusting balloon position in implantation makes radioactive particle close to lesions position.The appearance of the sacculus
Face is equipped with protrusion 5, and raised 5 use material identical with sacculus is made, or exclusive use other biological compatibility material
It is made, after balloon dilatation, sacculus can be preferably fixed on treatment position by protrusion 5, and sacculus is prevented to be subjected to displacement.Carry radiation
The sacculus of property particle can take out after completing therapeutic purposes, can also plant for a long time in the case where not influencing human normal function
Enter, the sacculus after taking-up re-uses after can replacing radioactive particle.The species type of the radioactive particle includes192Ir、198Au、169Y、131Cs、103Pd and125At least one of I.
Obviously, various changes and modifications can be made to the invention without departing from essence of the invention by those skilled in the art
Mind and range.In this way, if these modifications and changes of the present invention belongs to the range of the claims in the present invention and its equivalent technology
Within, then the present invention is also intended to include these modifications and variations.
Claims (10)
1. a kind of sacculus for carrying radioactive particle, which is characterized in that the sacculus is the ball used in body cavities or internal organs
Capsule is implanted into Shi Weiwei expanded state, and the balloon dilatation after the air of certain pressure or water are full makes balloon wall close to lesion portion
, fixed, support is played, expands, filling, be isolated, the function of embolism body cavities and internal organs, sacculus inner surface carries radiation
Property particle, there is protrusion in sacculus outer surface.
2. a kind of sacculus as described in claim 1 for carrying radioactive particle, which is characterized in that the sacculus is by medical elastic
Material is made, and identical with the sacculus material of the protrusion use is made, or is made using other biological compatibility material.
3. a kind of as claimed in claim 1 or 2 sacculus for carrying radioactive particle, which is characterized in that the sacculus be it is spherical,
Stick or other be adapted to the special shape of implantation position.
4. a kind of sacculus as claimed in claim 1 or 2 for carrying radioactive particle, which is characterized in that the sacculus is digestion
Sacculus in road, uterine cavity sacculus, intravaginal sacculus, biliary tract sacculus, one of blood saccule, intraperitoneal sacculus, urethra sacculus.
5. a kind of sacculus as described in claim 1 for carrying radioactive particle, which is characterized in that the carrying method is with viscous
Radioactive particle is adhered to the inner surface of balloon wall by mixture.
6. a kind of sacculus as described in claim 1 for carrying radioactive particle, which is characterized in that the carrying method is in ball
Radioactive particle is inserted into card slot when use by the card slot of intracapsular surface production radioactive particle.
7. a kind of such as the sacculus described in claim 5 or 6 for carrying radioactive particle, which is characterized in that the radioactive particle
It is dispersed evenly to entire sacculus inner surface.
8. a kind of such as the sacculus described in claim 5 or 6 for carrying radioactive particle, which is characterized in that according to specific tumour
Cell distribution accurately adjusts sacculus in implantation by radioactive particle integrated distribution in the sacculus inner surface close to lesions position
Position makes radioactive particle close to lesions position.
9. a kind of such as the sacculus described in claim 5 or 6 for carrying radioactive particle, which is characterized in that the radioactive particle
Species type be192Ir、198Au、169Y、131Cs、103Pd and125One of I or a variety of.
10. a kind of such as the sacculus described in claim 5 or 6 for carrying radioactive particle, which is characterized in that carry radioactive particle
Sacculus take out after completing therapeutic purposes or be chronically implanted in the case where not influencing human normal function.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910570998.1A CN110314274A (en) | 2019-06-27 | 2019-06-27 | A kind of sacculus carrying radioactive particle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910570998.1A CN110314274A (en) | 2019-06-27 | 2019-06-27 | A kind of sacculus carrying radioactive particle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110314274A true CN110314274A (en) | 2019-10-11 |
Family
ID=68120618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910570998.1A Pending CN110314274A (en) | 2019-06-27 | 2019-06-27 | A kind of sacculus carrying radioactive particle |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110314274A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112472995A (en) * | 2020-12-07 | 2021-03-12 | 党松松 | Silicone stent with radioactive particles for department of respiration |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1537647A (en) * | 2003-10-22 | 2004-10-20 | 高春平 | Tumour close internal rediation therapy device presetted in operation |
| CN1537648A (en) * | 2003-10-22 | 2004-10-20 | 高春平 | Saccule catheter type tumour close internal radiation therapy device |
| CN101631590A (en) * | 2007-03-12 | 2010-01-20 | 赛诺克斯有限公司 | Radiation catheter with multilayered balloon |
| CN201798827U (en) * | 2010-09-28 | 2011-04-20 | 上海交通大学医学院附属瑞金医院卢湾分院 | Biliary tract internal exposure support |
| CN208823772U (en) * | 2017-09-18 | 2019-05-07 | 王娟 | It is a kind of can short-term interpolation treatment tumour sacculus particle chain |
| CN211410672U (en) * | 2019-06-27 | 2020-09-04 | 原子高科股份有限公司 | Balloon carrying radioactive particles |
-
2019
- 2019-06-27 CN CN201910570998.1A patent/CN110314274A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1537647A (en) * | 2003-10-22 | 2004-10-20 | 高春平 | Tumour close internal rediation therapy device presetted in operation |
| CN1537648A (en) * | 2003-10-22 | 2004-10-20 | 高春平 | Saccule catheter type tumour close internal radiation therapy device |
| CN101631590A (en) * | 2007-03-12 | 2010-01-20 | 赛诺克斯有限公司 | Radiation catheter with multilayered balloon |
| CN201798827U (en) * | 2010-09-28 | 2011-04-20 | 上海交通大学医学院附属瑞金医院卢湾分院 | Biliary tract internal exposure support |
| CN208823772U (en) * | 2017-09-18 | 2019-05-07 | 王娟 | It is a kind of can short-term interpolation treatment tumour sacculus particle chain |
| CN211410672U (en) * | 2019-06-27 | 2020-09-04 | 原子高科股份有限公司 | Balloon carrying radioactive particles |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112472995A (en) * | 2020-12-07 | 2021-03-12 | 党松松 | Silicone stent with radioactive particles for department of respiration |
| CN112472995B (en) * | 2020-12-07 | 2022-08-12 | 杨云伟 | Silicone stent with radioactive particles for department of respiration |
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