CN102335052A - Anti-restenosis digestive tract stent - Google Patents
Anti-restenosis digestive tract stent Download PDFInfo
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- CN102335052A CN102335052A CN2011101983868A CN201110198386A CN102335052A CN 102335052 A CN102335052 A CN 102335052A CN 2011101983868 A CN2011101983868 A CN 2011101983868A CN 201110198386 A CN201110198386 A CN 201110198386A CN 102335052 A CN102335052 A CN 102335052A
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- digestive tract
- restenosis
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Abstract
The invention discloses an anti-restenosis digestive tract stent which is characterized in that a main body (1) is formed by connecting a plurality of stent units (2) and an easily-bent connecting part (3), wherein two ends of the connecting part (3) are respectively connected with the corresponding stent unit (2), the main body (1) is of a right circular cylinder structure which is easy to bend or a composite structure which is easy to bend and consists of a cylinder and a cone; and each stent unit (2) is of an integral structure formed by carving a metal pipe material or a structure formed by weaving a silk material, and the connecting part (3) is formed by weaving a metal line material or plastic line material with good flexibility. The anti-restenosis digestive tract stent has better radial supporting strength and better compliance, and ensures that the stent has the advantages of more accuracy of positioning, difficulty in translocation, low restenosis incidence and the like.
Description
Technical field
The present invention relates to a kind of medical device tool; Especially inner support is used in a kind of digestive tract treatment; Specifically a kind of be used to treat the digestive tract that different reasons cause narrow, symptom such as block, also can be used for the anti-restenosis digestive tract inner support of the treatment of tumor locus in the digestive tract simultaneously.
Background technology
Under many circumstances, the intravital digestive tract of people can be because tumor etc. be former thereby cause or block that if can not get treating timely and effectively, dysphagia appears in most of patient, then can make the deterioration that is in a bad way narrow, and health descends rapidly and causes death.Because operation risk is higher, the post-operative recovery cycle is long, less patient suffering is bigger, then need take nonoperative Therapeutic Method to remove narrow or block and wait the interior symptom of digestive tract.Along with the development of interventional radiology and endoscopic technic, utilize the pathological changes in the less invasive techniques treatment digestive tract to obtain increasing application clinically, this operation technique is simple, risk is low, wound is little.Wherein a kind of important mode imports elastomeric network in lesions exactly, and support can arrive original diameter by self expandable after inserting narrow digestive tract, and narrow tube wall is produced the expansionary force that continues, and keeps the stable of support.
Because present support mainly is an integrated bracket, rigidity is bigger, and the compliance of support of the type and body lumen wall has certain shortcoming; Be difficult for complying with gastral bending, close weak effect, be difficult to be fixed in the digestive tract stenosis with the wall of the lumen card; And be prone to be shifted; Do not have expansion and support narrow effect, the stimulation to tube wall simultaneously is bigger, and its main complication is presented as the granulation tissue hyperplasia after support is implanted and the restenosis that causes; Follow-up need be through excision hypertrophy granulation tissue or implant the generation that new support is treated restenosis again, conventional bracket is to the tumor unrestraint effect in the digestive tract simultaneously.
Summary of the invention
The objective of the invention is can not adapt to flexural deformation to existing digestive tract inner support, location difficulty is prone to cause problems such as restenosis; Design and a kind ofly guaranteeing that support more is prone to comply with gastral bending, applying wall of the lumen under the unobstructed prerequisite of digestive tract; Be fixed in the digestive tract stenosis better, the difficult displacement played expansion and supported narrow effect; Littler to the stimulation of tube wall simultaneously, can prevent the support postoperative restenosis also can prevent the anti-restenosis digestive tract inner support of curing oncoma better.
Technical scheme of the present invention is:
A kind of anti-restenosis digestive tract inner support; The main body 1 that it is characterized in that it is formed by connecting with the link 3 that is easy to bending some carrier units 2 with certain rigidity and supporting role; The two ends of described link 3 link to each other with corresponding carrier unit 2 respectively, and described main body 1 is the complex structure that is easy to bending that is easy to crooked right circular cylinder structure or is made up of cylinder and cone; Described carrier unit 2 is engraved overall structure that forms or the structure that is formed by the braiding of silk material by metal pipe material, and link 3 is formed by flexibility good metal wire rod or plastic wire braiding.
The two-end structure 4 of the main body 1 of described support is horn mouth, bulb or rim of a cup shape.
The main body 1 of described support interior is or/and outer surface is local or all be covered with overlay film, and the two ends of overlay film are added with shirt rim 10, and described overlay film is the polymer coating with good biocompatibility.
Radioactive particle filling capsule 8 is equipped with on the surface of the main body 1 of described support, and the material of radioactive particle filling capsule 8 is medical high polymer tubing or medical metal tubing, is shaped as long tubular or single capsule structure.
The quantity of described radioactive particle filling capsule 8 is for being at least one, and it is arranged evenly along the arrangement of branches such as circumference or the rhombus of main body.
The film tube 5 that the surface coverage of described link 3 is processed by some covering materials does not link to each other between the adjacent membranes tube 5 mutually, and each film tube 5 all connects with corresponding carrier unit 2.
Described each carrier unit 2 is made up of support unit 7 and linkage unit 6.
Anti-restenosis digestive tract inner support of the present invention, main body rack connects several carrier units the complex that combines right circular cylinder or be made up of a plurality of cylinders, cone by link.Carrier unit is to be engraved by metal pipe material to form or formed by silk material braiding, and link is made up of materials such as good metal wire rod of flexibility or plastic wires.Carrier unit is made up of linkage unit and support unit; Two kinds of unitary structures can be known structure; Also can be other structure, for example linkage unit can be V-arrangement, irregular waveform etc.; Support unit can be sinusoidal wave form, waveform, many M shape etc.; Arrangement mode is selected as required, and for example linkage unit can be distributed between two crests of support unit, between crest-trough, between trough-trough, between the brace rod etc., the linkage unit of different structure and support unit can rule or irregular be distributed in same or the different support unit on.The two ends of main body rack can be deformed into shapes such as horn mouth, bulb, rim of a cup according to the difference of diseased region.Radioactive particle filling capsule can be equipped with in the surface of main body rack, and the material and the shape of radioactive particle filling capsule can be decided as required.Radioactive particle filling capsule can be one or more.It can be arranged along branches such as circumference, and is also can rhombus arranged evenly, also can asymmetricly distribute, and arranges as required.Described support interior be or/and outer surface can be local or whole overlay films, and add the shirt rim, and overlay film is the macromolecular material with good biocompatibility.The film tube that the link surface coverage is processed by covering material, both do not link together, and the part of film tube is connected with carrier unit
The invention has the beneficial effects as follows:
A, the present invention can satisfy the requirement of current armarium Wicresoft operation, completions of can once performing the operation, and operation technique makes things convenient for, Wicresoft, and risk is low, less patient suffering is little, surgery cost also can effectively reduce;
B, carrier unit structure Design, the compliance guaranteeing to have increased under the prerequisite of support intensity support itself alleviates the compressing of support to the digestive tract inwall; Make support more be prone to comply with gastral bending, applying digestive tract inwall is fixed in stenosis better; The difficult displacement; Play expansion and support narrow effect, littler to the stimulation of tube wall simultaneously, prevent optimum restenosis behind the stenting better.
C, rack surface can carry the design of radioactive particle filling capsule, make things convenient for the doctor in operating process, to load radioactive particle, in implant frame, also can carry out radiation treatment to tumor, thereby help to suppress or kill tumor cell;
D, radioactive particle filling capsule can carry out different arranging with the requirement in zone to radioactive particle according to the clinical radiological dose of doctor, satisfy the digestive tract tumor treatment, reduce the damage to normal surrounding tissue simultaneously.
Segmental structure support of the present invention, support integral body be by each unitary combination, and each carrier unit adopts the metal pipe material of good biocompatibility to engrave to form; Each carrier unit is guaranteeing to make support more be prone to comply with gastral bending, applying wall of the lumen under the unobstructed prerequisite of digestive tract; Be fixed in the digestive tract stenosis better, the difficult displacement played expansion and supported narrow effect; Littler to the stimulation of tube wall simultaneously, prevent the support postoperative restenosis better.Support two ends shape variation can also be carried the radioactive particle capsule simultaneously for providing more choices property of treatment, has realized that conventional expansion tract combines with radiation treatment.The present invention has promptly solved the complication problem of conventional bracket implantation restenosis, can play therapeutical effect to a certain degree to tumor again, has the clinical practice promotional value.
The invention solves the clinical difficult problem of part, have novel structure, Wicresoft's operation, less patient suffering is little, and the advantage that complication is few has boundless potential applicability in clinical practice.
The present invention is simple in structure, and is easily manufactured, when having good radial support intensity, also has good compliance, can make support location more accurate, is difficult for displacement, the restenosis incidence rate is low.
Description of drawings
Fig. 1 is a supporting structure sketch map of the present invention.
Fig. 2, the 3rd, one of carrier unit structural representation of the present invention.
Fig. 3 be carrier unit structural representation of the present invention give an example two.
Fig. 4 is that support film barrel structure sketch map of the present invention is given an example.
Fig. 5 be support of the present invention carry the radioactive particle capsule structural representation for example.
Fig. 6 is that the linkage unit of carrier unit of the present invention and the structural representation of support unit are given an example.
Fig. 7 is one of structural representation of diseased region in the support implant into body digestive tract of the present invention.
Fig. 8 be diseased region in the support implant into body digestive tract of the present invention structural representation two.
The specific embodiment
Below in conjunction with accompanying drawing and embodiment the present invention is further described.
Embodiment one.
Shown in Fig. 1-7.
A kind of anti-restenosis digestive tract inner support (like Fig. 1,2, shown in 3), rack body 1 connects the complex that combines right circular cylinder or be made up of a plurality of cylinders, cone by link 3 with several carrier units 2.Its maximum characteristics are can be crooked arbitrarily to adapt to gastral curved shape at link 3 places, and the quantity of link 3 is littler 1 than the quantity of carrier unit 2.Carrier unit 2 is to be engraved by metal pipe material (like the titanium pipe) to form, and also can adopt the structure with certain rigidity that is formed by the braiding of silk material shown in Figure 6, and link 3 is made up of materials such as good metal wire rod of flexibility or plastic wires.When carrier unit 2 adopted braiding structure, it can be made up of linkage unit 6 and support unit 7, and two kinds of unitary structures can be known structure, also can be other structure, and its arrangement mode carries out multiple choices (as shown in Figure 6) as required.
During practical implementation as required the two-end structure 4 of rack body 1 can be out of shape shapes such as horn mouth, bulb, rim of a cup.Rack body 1 interior is or/and outer surface can be local or whole overlay films; And add shirt rim 10; Overlay film can adopt the macromolecular material with good biocompatibility; The surface of link 3 also can cover the film tube of being processed by covering material 5, and adjacent film tube does not link together between the two, but the dash area 9 of expression film tube 5 is connected (as shown in Figure 4) with carrier unit 2 among Fig. 4.
During use; Doctor elder generation is with the support compression and insert stent conveying device; Guide at seal wire; Under the auxiliary supervision effect of X line or endoscope rack body 1 is delivered to pathological changes narrow positions and release, support accurately is fixed on stenosis in the digestive tract, recovers its shape again and expand to strut narrow maintenance drain unobstructed (as shown in Figure 7).
Embodiment two.
Like Fig. 5, shown in 8.
A kind of anti-restenosis digestive tract inner support (as shown in Figure 5); The radioactive particle capsule 8 that is used to treat tumor can also be carried in the surface of rack body 1; The material of radioactive particle filling capsule 8 is medical high polymer tubing or medical metal tubing etc., is shaped as long tubular, single capsule structure etc.
Radioactive particle filling capsule 8 can be one or more, and it can be arranged along branches such as circumference, and is also can rhombus arranged evenly, also can asymmetricly distribute.
During use; The doctor fills radioactive particle for 8 li at radioactive particle filling capsule in advance, then with the support compression and insert stent conveying device, guides at seal wire; Under the auxiliary supervision effect of X line or endoscope main body rack 1 is delivered to pathological changes narrow positions and release; Support accurately is fixed on stenosis in the digestive tract, recovers its shape again and expand to strut narrow maintenance drain unobstructed (as shown in Figure 8), and radioactive particle can be treated tumor simultaneously.
The materials of the material of the support that the present invention does not relate to, method for preparing, overlay film etc. are all identical with existing support maybe can to adopt prior art to realize.
Claims (7)
1. anti-restenosis digestive tract inner support; The main body (1) that it is characterized in that it is some carrier units (2) and be easy to crooked link (3) and be formed by connecting; The two ends of described link (3) link to each other with corresponding carrier unit (2) respectively, and described main body (1) is the complex structure that is easy to bending that is easy to crooked right circular cylinder structure or is made up of cylinder and cone; Described carrier unit (2) is engraved overall structure that forms or the structure that is formed by the braiding of silk material by metal pipe material, and link (3) is formed by flexibility good metal wire rod or plastic wire braiding.
2. support according to claim 1 is characterized in that the two-end structure (4) of the main body (1) of described support is horn mouth, bulb or rim of a cup shape.
3. support according to claim 1; It is characterized in that main body (1) interior of described support or/and outer surface is local or all be covered with overlay film; The two ends of overlay film are added with shirt rim (10), and described overlay film is the polymer coating with good biocompatibility.
4. support according to claim 1; Radioactive particle filling capsule (8) is equipped with on the surface that it is characterized in that the main body (1) of described support; The material of radioactive particle filling capsule (8) is medical high polymer tubing or medical metal tubing, is shaped as long tubular or single capsule structure.
5. support according to claim 4, the quantity that it is characterized in that described radioactive particle filling capsule (8) is for being at least one, and it is arranged evenly along the arrangement of branches such as circumference or the rhombus of main body ().
6. support according to claim 1; It is characterized in that the film tube (5) that the surface coverage of described link (3) is processed by some covering materials; Do not link to each other mutually between the adjacent membranes tube (5), each film tube (5) all connects with corresponding carrier unit (2).
7. support according to claim 1 is characterized in that described each carrier unit (2) is made up of support unit (7) and linkage unit (6).
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CN2011101983868A CN102335052A (en) | 2011-07-15 | 2011-07-15 | Anti-restenosis digestive tract stent |
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CN2011101983868A CN102335052A (en) | 2011-07-15 | 2011-07-15 | Anti-restenosis digestive tract stent |
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Cited By (15)
Publication number | Priority date | Publication date | Assignee | Title |
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CN103301561A (en) * | 2012-03-16 | 2013-09-18 | 吴沛宏 | High-flexibility radioactive particle and implanting method thereof |
CN103301560A (en) * | 2012-03-16 | 2013-09-18 | 吴沛宏 | Radioactive particles for treating tumor and implantation method |
CN104367399A (en) * | 2014-11-05 | 2015-02-25 | 南京微创医学科技有限公司 | Super compliable recyclable film-covered subsection support and manufacturing method thereof |
CN106344210A (en) * | 2016-11-17 | 2017-01-25 | 浙江归创医疗器械有限公司 | Medicine-applying filming support |
CN106420127A (en) * | 2016-10-15 | 2017-02-22 | 韩新巍 | Fully fitting esophageal stent complying with esophageal peristalsis |
CN107296668A (en) * | 2017-08-01 | 2017-10-27 | 有研医疗器械(北京)有限公司 | A kind of non-film-coated vascular support and its method for releasing |
WO2018188059A1 (en) * | 2017-04-14 | 2018-10-18 | 深圳市方鹏科技有限公司 | Blockage-proof inner core of fuel pipe of intelligent car |
CN108992219A (en) * | 2018-08-25 | 2018-12-14 | 山东瑞安泰医疗技术有限公司 | A kind of overlay film esophageal stents of anti-displacement and preparation method thereof |
CN109172069A (en) * | 2018-10-25 | 2019-01-11 | 杭州捷诺飞生物科技股份有限公司 | Digestive tract stent and manufacturing process thereof |
CN109893309A (en) * | 2019-03-05 | 2019-06-18 | 东华大学 | The degradable esophagus pipe holder of the antiskid self expandable of negative poisson's ratio structure and its preparation |
CN110037839A (en) * | 2019-05-28 | 2019-07-23 | 南京微创医学科技股份有限公司 | A kind of intracavity stent and preparation method thereof |
WO2019196380A1 (en) | 2018-04-12 | 2019-10-17 | 杭州糖吉医疗科技有限公司 | Gastric diverter and digestive tract support and release method thereof |
CN110461382A (en) * | 2017-01-25 | 2019-11-15 | B.布劳恩梅尔松根股份公司 | Intracavitary unit |
CN112716660A (en) * | 2020-12-16 | 2021-04-30 | 河北工业大学 | Series-parallel connection type shape memory alloy vertebral body support |
CN110072473B (en) * | 2016-10-04 | 2024-03-22 | 微仙美国有限公司 | Method and device for stent delivery |
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CN1736349A (en) * | 2004-08-17 | 2006-02-22 | 微创医疗器械(上海)有限公司 | Combined membrane-covered stent capable of being bent in any direction |
CN101484089A (en) * | 2005-04-04 | 2009-07-15 | 柏比材料科技有限公司 | Flexible stent |
CN2845770Y (en) * | 2005-09-09 | 2006-12-13 | 沈刚 | Medical rack |
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Cited By (20)
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CN103301561A (en) * | 2012-03-16 | 2013-09-18 | 吴沛宏 | High-flexibility radioactive particle and implanting method thereof |
CN103301560A (en) * | 2012-03-16 | 2013-09-18 | 吴沛宏 | Radioactive particles for treating tumor and implantation method |
CN104367399A (en) * | 2014-11-05 | 2015-02-25 | 南京微创医学科技有限公司 | Super compliable recyclable film-covered subsection support and manufacturing method thereof |
CN104367399B (en) * | 2014-11-05 | 2017-01-18 | 南京微创医学科技股份有限公司 | Super compliable recyclable film-covered subsection support and manufacturing method thereof |
CN110072473B (en) * | 2016-10-04 | 2024-03-22 | 微仙美国有限公司 | Method and device for stent delivery |
CN106420127B (en) * | 2016-10-15 | 2019-03-15 | 郑州大学第一附属医院 | One kind complying with esophageal peristalsis and is bonded Esophageal Stent entirely |
CN106420127A (en) * | 2016-10-15 | 2017-02-22 | 韩新巍 | Fully fitting esophageal stent complying with esophageal peristalsis |
CN106344210A (en) * | 2016-11-17 | 2017-01-25 | 浙江归创医疗器械有限公司 | Medicine-applying filming support |
US11324862B2 (en) | 2017-01-25 | 2022-05-10 | B. Braun Melsungen Ag | Endoluminal device |
CN110461382A (en) * | 2017-01-25 | 2019-11-15 | B.布劳恩梅尔松根股份公司 | Intracavitary unit |
WO2018188059A1 (en) * | 2017-04-14 | 2018-10-18 | 深圳市方鹏科技有限公司 | Blockage-proof inner core of fuel pipe of intelligent car |
CN107296668A (en) * | 2017-08-01 | 2017-10-27 | 有研医疗器械(北京)有限公司 | A kind of non-film-coated vascular support and its method for releasing |
WO2019196380A1 (en) | 2018-04-12 | 2019-10-17 | 杭州糖吉医疗科技有限公司 | Gastric diverter and digestive tract support and release method thereof |
CN108992219A (en) * | 2018-08-25 | 2018-12-14 | 山东瑞安泰医疗技术有限公司 | A kind of overlay film esophageal stents of anti-displacement and preparation method thereof |
CN109172069A (en) * | 2018-10-25 | 2019-01-11 | 杭州捷诺飞生物科技股份有限公司 | Digestive tract stent and manufacturing process thereof |
CN109172069B (en) * | 2018-10-25 | 2021-07-06 | 杭州捷诺飞生物科技股份有限公司 | Process for manufacturing digestive tract stent |
CN109893309A (en) * | 2019-03-05 | 2019-06-18 | 东华大学 | The degradable esophagus pipe holder of the antiskid self expandable of negative poisson's ratio structure and its preparation |
CN110037839A (en) * | 2019-05-28 | 2019-07-23 | 南京微创医学科技股份有限公司 | A kind of intracavity stent and preparation method thereof |
CN110037839B (en) * | 2019-05-28 | 2024-03-12 | 南微医学科技股份有限公司 | Endoluminal stent and preparation method thereof |
CN112716660A (en) * | 2020-12-16 | 2021-04-30 | 河北工业大学 | Series-parallel connection type shape memory alloy vertebral body support |
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Application publication date: 20120201 |