CN201123915Y - Medical radioactive double-membrane NiTi alloy endovascular stent - Google Patents

Medical radioactive double-membrane NiTi alloy endovascular stent Download PDF

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Publication number
CN201123915Y
CN201123915Y CN 200720076640 CN200720076640U CN201123915Y CN 201123915 Y CN201123915 Y CN 201123915Y CN 200720076640 CN200720076640 CN 200720076640 CN 200720076640 U CN200720076640 U CN 200720076640U CN 201123915 Y CN201123915 Y CN 201123915Y
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China
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niti alloy
membrane
utility
stent
type polyurethane
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Expired - Fee Related
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CN 200720076640
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Chinese (zh)
Inventor
李楠
程树群
郭卫星
李�昊
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Individual
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Abstract

The utility model belongs to the medical appliance category and relates to a NiTi alloy intravascular stent which is implanted into the blood vessel of the human body and is covered with radioactive double membranes. To solve the problems that the prior intravascular stent fails to suppress the growth of the tumor and is easy to form thrombus and so on, the stent of the utility model is a self-expanding NiTi alloy intravascular stent, a NiTi alloy sheet with the thickness of 0.1 to 0.3mm is produced into a tubular mesh structure, the tube diameter is between 0.2 and 2cm, and the length is between 2 and 3cm. The inner wall of the stent is covered with a layer of polycarbonate type polyurethane membrane, and the outer wall is covered with a polycarbonate type polyurethane radioactive isotope membrane. The utility model applies a novel membrane forming material, namely the fatty group polycarbonate type polyurethane, has good biocompatibility, and can effectively dilate and support blood vessels, and the isotope membrane of the outer layer can effectively suppress the growth of the tumors in the regions around the blood vessels. The NiTi alloy intravascular stent has easy processing and manufacturing, low cost, strong practicability, and broad market prospect.

Description

The two film NiTi alloy endovascular stents of medical radioactive
Affiliated technical field
This utility model belongs to the medical apparatus and instruments category, relates to a kind of NiTi alloy endovascular stent of implant into body blood vessel, internal and external walls one deck fatty poly-ester carbonate type polyurethane film that respectively is covered, and adventitia is with radiosiotope.
Background technology
At present, widely used medical metal endovascular stent, be used for the treatment of benign diseases such as coronary vasodilator and peripheral blood vessel be narrow more, but in the clinical treatment work, often there is the entity tumor compressing to invade the situation of the important blood vessels or the vascularization cancer embolus of directly growing into, place conventional endovascular stent and no doubt can expand support blood vessels, but uncontrollable tumor growth.For the tumor of invading important blood vessels,, also only can play the compressing shielding action to tumor even use the endovascular stent of overlay film.Present known membrane material histocompatibility is not good, easily forms thrombosis.Known radioactivity endovascular stent, how by isotopic ion inject, the reactor activation or mixes with high polymeric solution the back directly mode such as coating obtain, preceding dual mode cost high usage is low, after a kind of mode radiological dose wayward.In view of still there are many defectives in above-mentioned existing endovascular stent, the design people develops this utility model in conjunction with the clinical position actual needs--the two film NiTi alloy endovascular stents of radioactivity, make its instructions for use that more gears to actual circumstances, and have more the market competitiveness.
Summary of the invention
Existing metallic blood vessel inner support is many can not effectively to be suppressed tumor growth and easily form many defectives such as thrombosis in order to solve, this utility model provides a kind of NiTi alloy endovascular stent that is covered with two films, this NiTi alloy endovascular stent is behind its implant into body blood vessel, because novel filmogen fatty poly-ester carbonate type polyurethane, excellent biological compatibility and elasticity are arranged, be difficult for forming thrombosis, can effectively expand support blood vessels, guarantee the unobstructed of blood flow, and outer isotope film can play inhibitory action to the growth of enclosing the angiosomes tumor tissues, and it is better to apply the chemotherapy medicine antitumor effect as inner membrance.This utility model processing and manufacturing is easy, and cost is low.
This utility model solves its technical problem and realizes by the following technical solutions.According to the two film NiTi alloy endovascular stents of the radioactivity that the utility model proposes, comprising: the NiTi alloy endovascular stent, it is characterized in that at the inside and outside one deck fatty poly-ester carbonate type polyurethane film that respectively is covered of support, and adventitia is with radiosiotope.
The technical scheme that this utility model adopted specifically realizes by following steps:
The used support of this utility model is a self-expanding formula NiTi alloy endovascular stent, is the tubular reticulum formula structure stand of being made by the NiTi alloy sheets of thick 0.1-0.3mm, divides a plurality of specifications, and the pipe diameter is 0.2-2cm, length 2-3cm.Be used for to choose big its inflated tube of specification support when the liver portal vein supports and directly reach 2cm.
Described rack inner wall covers one deck fatty poly-ester carbonate type polyurethane film, and this film inner surface can apply or not apply antitumor drug.
Described support outer wall covers one deck fatty poly-ester carbonate type polyurethane radiosiotope film.
Above-mentioned radiosiotope film can make by two kinds of methods: determine that by enclosing the required irradiation dose of angiosomes radioisotopic activity, dosage add in the polycarbonate polyurethane film when the system film; Or after the adventitia film forming, will be dissolved with the surface that radioisotopic solvent is directly coated film.
The beneficial effects of the utility model are, owing to use novel filmogen fatty poly-ester carbonate type polyurethane, excellent biological compatibility and elasticity are arranged, be difficult for forming thrombosis, can effectively expand support blood vessels, guarantee the unobstructed of blood flow, adventitia can play effective inhibitory action to the growth of enclosing the angiosomes tumor tissues for the isotope film, and then antitumous effect is better as selecting the medicine inner membrance.This utility model processing and manufacturing is easy, and is with low cost, more suits the needs of clinical medicine treatment.
This utility model really belongs to innovation at aspects such as material, structure and manufacturing technologies, than the product structure and the bigger again improvement of function aspects and perfect of present use, and practical, have vast market prospect.
Description of drawings
Accompanying drawing 1 is an organigram of the present utility model.
Accompanying drawing 2 is profiles of the present utility model.
1.NiTi alloy endovascular stent, 2. inner membrance among the figure--fatty poly-ester carbonate type polyurethane film-normal film or pharmaceutical film, 3. adventitia--fatty poly-ester carbonate type polyurethane radiosiotope film.
Below in conjunction with drawings and Examples this utility model is further specified.
The specific embodiment
Reach specific embodiment in conjunction with the accompanying drawings and describe this utility model in detail.
As shown in the figure, when the two film NiTi alloy endovascular stents of this utility model radioactivity were positioned in the narrow section blood vessel, self-expanding formula NiTi alloy endovascular stent 1 is expansion automatically, and narrow or the section of blocking are strutted, recover the unobstructed property of blood vessel, improve the hemoperfusion of tissue.As placing rack in liver cancer and portal vein cancer patient's portal vein the time, caliber can reach 2cm after choosing big its self-expanding of specification support, fully play a supporting role, support inner membrance fatty poly-ester carbonate type polyurethane film 2, histocompatibility is good, but effectively preventing thrombosis, support epicardial fat adoption carbonic ester type polyurethane radiosiotope film 3 can local radiotherapy kill blood vessel peripheral region and endovascular cancerous cell, avoids cancer embolus to form once more.
The foregoing description is a most preferred embodiment of the present utility model, and this embodiment had both expanded and supported narrow blood vessel, had recovered the unobstructed of blood flow, has effectively suppressed to enclose the growth of angiosomes tumor tissues again.Present embodiment is not that this utility model is done any type of restriction, and all any simple change, equivalent variations and modifications of the foregoing description being made according to technical spirit of the present utility model all belong to category of the present utility model.

Claims (3)

1. two film NiTi alloy endovascular stents of a radioactivity comprise: the NiTi alloy endovascular stent, it is characterized in that at the inside and outside one deck fatty poly-ester carbonate type polyurethane film that respectively is covered of support, and adventitia is with radiosiotope.
2. NiTi alloy endovascular stent as claimed in claim 1 is characterized in that: by the tubular reticulum formula structure stand that the NiTi alloy sheets of thick 0.1-0.3mm is made, the pipe diameter is 0.2-2cm, length 2-3cm.
3. NiTi alloy endovascular stent as claimed in claim 1 is characterized in that: apply antitumor drug on the fatty poly-ester carbonate type polyurethane film of rack inner wall lining.
CN 200720076640 2007-10-25 2007-10-25 Medical radioactive double-membrane NiTi alloy endovascular stent Expired - Fee Related CN201123915Y (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 200720076640 CN201123915Y (en) 2007-10-25 2007-10-25 Medical radioactive double-membrane NiTi alloy endovascular stent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 200720076640 CN201123915Y (en) 2007-10-25 2007-10-25 Medical radioactive double-membrane NiTi alloy endovascular stent

Publications (1)

Publication Number Publication Date
CN201123915Y true CN201123915Y (en) 2008-10-01

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CN 200720076640 Expired - Fee Related CN201123915Y (en) 2007-10-25 2007-10-25 Medical radioactive double-membrane NiTi alloy endovascular stent

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CN (1) CN201123915Y (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107249654A (en) * 2015-03-12 2017-10-13 犹他-仁荷Dds及新医疗技术开发共同研究所 Cell spaces are coated with the support of functional materials
CN107744414A (en) * 2017-11-29 2018-03-02 成都创客之家科技有限公司 A kind of film-coated vascular support
CN109183129A (en) * 2018-09-11 2019-01-11 西安理工大学 A method of for medical titanium nickel alloy surfaces polyurethane coating

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107249654A (en) * 2015-03-12 2017-10-13 犹他-仁荷Dds及新医疗技术开发共同研究所 Cell spaces are coated with the support of functional materials
CN107744414A (en) * 2017-11-29 2018-03-02 成都创客之家科技有限公司 A kind of film-coated vascular support
CN109183129A (en) * 2018-09-11 2019-01-11 西安理工大学 A method of for medical titanium nickel alloy surfaces polyurethane coating

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Granted publication date: 20081001

Termination date: 20091125