CN110215600A - The implantation material of radion can be carried - Google Patents
The implantation material of radion can be carried Download PDFInfo
- Publication number
- CN110215600A CN110215600A CN201910448510.8A CN201910448510A CN110215600A CN 110215600 A CN110215600 A CN 110215600A CN 201910448510 A CN201910448510 A CN 201910448510A CN 110215600 A CN110215600 A CN 110215600A
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- China
- Prior art keywords
- radion
- prosthese
- carrying
- storage warehouse
- implantation material
- Prior art date
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- 238000002513 implantation Methods 0.000 title claims abstract description 36
- 239000000463 material Substances 0.000 title claims abstract description 31
- 238000003860 storage Methods 0.000 claims abstract description 68
- 238000007789 sealing Methods 0.000 claims abstract description 20
- 230000000903 blocking effect Effects 0.000 claims abstract description 4
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims description 20
- 239000010936 titanium Substances 0.000 claims description 20
- 229910052719 titanium Inorganic materials 0.000 claims description 20
- 210000000988 bone and bone Anatomy 0.000 claims description 14
- 229910003460 diamond Inorganic materials 0.000 claims description 6
- 239000010432 diamond Substances 0.000 claims description 6
- 206010028980 Neoplasm Diseases 0.000 abstract description 26
- 238000001959 radiotherapy Methods 0.000 abstract description 19
- 230000006378 damage Effects 0.000 abstract description 9
- 239000011159 matrix material Substances 0.000 abstract description 3
- 210000001519 tissue Anatomy 0.000 description 12
- 238000002271 resection Methods 0.000 description 10
- 239000002245 particle Substances 0.000 description 7
- 238000002725 brachytherapy Methods 0.000 description 6
- 230000002285 radioactive effect Effects 0.000 description 6
- 239000001993 wax Substances 0.000 description 6
- 210000000695 crystalline len Anatomy 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 5
- 206010005949 Bone cancer Diseases 0.000 description 4
- 229910001069 Ti alloy Inorganic materials 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 210000004872 soft tissue Anatomy 0.000 description 4
- 238000010146 3D printing Methods 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- ZCYVEMRRCGMTRW-YPZZEJLDSA-N iodine-125 Chemical compound [125I] ZCYVEMRRCGMTRW-YPZZEJLDSA-N 0.000 description 3
- 229940044173 iodine-125 Drugs 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 230000002411 adverse Effects 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 230000005855 radiation Effects 0.000 description 2
- 230000000451 tissue damage Effects 0.000 description 2
- 231100000827 tissue damage Toxicity 0.000 description 2
- 239000011800 void material Substances 0.000 description 2
- 206010003694 Atrophy Diseases 0.000 description 1
- 208000010392 Bone Fractures Diseases 0.000 description 1
- 241001457926 Brachys Species 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 229910000883 Ti6Al4V Inorganic materials 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 230000037444 atrophy Effects 0.000 description 1
- 235000013871 bee wax Nutrition 0.000 description 1
- 239000012166 beeswax Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000013467 fragmentation Methods 0.000 description 1
- 238000006062 fragmentation reaction Methods 0.000 description 1
- 238000007306 functionalization reaction Methods 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000003439 radiotherapeutic effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 238000007086 side reaction Methods 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1002—Intraluminal radiation therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N2005/1019—Sources therefor
- A61N2005/1023—Means for creating a row of seeds, e.g. spacers
Abstract
The present invention provides the implantation materials that one kind can carry radion, are related to tumour radiotherapy technical field, design to alleviate radiotherapy tumour to the big problem of patient body damage.The implantation material that radion can be carried includes prosthese, multiple storage warehouses and multiple sealing elements;Multiple storage warehouses are offered on the prosthese, the storage warehouse is for carrying radion, and the sealing element is for blocking the storage warehouse.The implantation material for carrying radion that the invention provides can guarantee that radion can carry out radiotherapy to tumor locus, will not damage to other normal matrix.
Description
Technical field
The present invention relates to tumour radiotherapy technical fields, in particular to the implantation material that can carry radion.
Background technique
Seeds implantation technology belongs to the plesioradiotherapy scope of radiotherapeutics.Close-range treatment
The noun of [brachytherapy (BT)] derives from Greece's word brachy, is the close meaning, means radioactive source is close or plants
Enter tumour body to treat tumour, is namely opposite with external exposure with " remote ".Plesioradiotherapy technology includes: intracavitary close
Brachytherapy, Implantation brachytherapy, introoperative radiotherapy and mould treatment etc. in radiotherapy, pipe.Implantation brachytherapy is according to closing
Residence time can be divided between transience tissue brachytherapy between brachytherapy and permanent tissue to radioactive source again in vivo.Its
Middle radioactivity iodine-125 seeds implanted then belongs to irradiation at short distance technology between permanent tissue.
Currently, treating tumour in the prior art: after tumor resection, radion can be directly placed in by medical worker
In the cavity left after tumor resection, after radioactive prospecting instrument, because the activity of soft tissue is stronger, there are particles to fall off, swims
From etc. risks, generation situations such as local normal tissue raying can be caused downright bad once falling off occurs in radioactive particle.Alternatively, will
After tumor resection, supporting prostheses are set, then by In Vitro Chemotherapy, still in the cavity that medical worker leaves after tumor resection
Such therapeutic modality can equally cause compared with major injury patient.
Therefore it provides a kind of small implantation material for carrying radion of harm for the treatment of is wanted as those skilled in the art
The important technological problems of solution.
Summary of the invention
The purpose of the present invention is to provide the implantation materials that one kind can carry radion, to alleviate axiolite in the prior art
Son treatment tumour is easy to other normal hurtful technical problems of collective organization.
The embodiment of the invention provides the implantation materials that one kind can carry radion, including prosthese and multiple sealing elements;
Multiple storage warehouses are offered on the prosthese, for carrying radion, the sealing element is used for the storage warehouse
Block the storage warehouse.
The first possible embodiment provided in an embodiment of the present invention, wherein above-mentioned prosthese uses porous titanium framework.
Second of possible embodiment provided in an embodiment of the present invention, wherein the internal void of above-mentioned porous titanium framework
Using diamond lens structure.
The third possible embodiment provided in an embodiment of the present invention, wherein the aperture of above-mentioned porous titanium framework is 640
μm。
4th kind of possible embodiment provided in an embodiment of the present invention, wherein above-mentioned prosthese is in cylindroid;
The storage warehouse is provided with the side wall of the prosthese.
5th kind of possible embodiment provided in an embodiment of the present invention, wherein 16 institutes are offered on above-mentioned prosthese
Storage warehouse is stated, and the storage warehouse is divided into two groups of both ends that the prosthese is arranged in.
6th kind of possible embodiment provided in an embodiment of the present invention, wherein storage warehouse described in above-mentioned every group is described in
The circumferential direction of prosthese is uniformly arranged.
7th kind of possible embodiment provided in an embodiment of the present invention, wherein above-mentioned every group of the equal position of the storage warehouse
In in same plane.
8th kind of possible embodiment provided in an embodiment of the present invention, wherein the center of storage warehouse described in above-mentioned every group
The distance between the end face of the prosthese that point is adjacent to L is 2.75mm.
9th kind of possible embodiment provided in an embodiment of the present invention, wherein above-mentioned sealing element uses bone wax.
The utility model has the advantages that
The embodiment of the invention provides the implantation materials that one kind can carry radion, including prosthese and multiple sealing elements;It is false
Multiple storage warehouses are offered on body, storage warehouse is for carrying radion, and sealing element is for blocking storage warehouse.Before the use,
Medical worker can carry out tumor resection operation to patient, and then prosthese is placed on the position that patient is removed tumour by medical worker
It sets, and offers multiple storage warehouses on prosthese, when using prosthese, can be deposited by radion in storage warehouse, and pass through sealing
Part is sealed the opening of storage warehouse, to suturing at patient incision after placing prosthese;By opening up storage on prosthese
The such setting of storage, can guarantee that the position of radion will not fall off because of radion or dissociate and change,
Guarantee that radion can carry out radiotherapy to tumor locus, other normal matrix will not be damaged.
Detailed description of the invention
It, below will be to specific in order to illustrate more clearly of the specific embodiment of the invention or technical solution in the prior art
Embodiment or attached drawing needed to be used in the description of the prior art be briefly described, it should be apparent that, it is described below
Attached drawing is some embodiments of the present invention, for those of ordinary skill in the art, before not making the creative labor
It puts, is also possible to obtain other drawings based on these drawings.
Fig. 1 is that the overall structure diagram of the implantation material provided in an embodiment of the present invention for carrying radion is (wherein close
Sealing is not shown);
Fig. 2 is the partial enlarged view in Fig. 1 at B;
Fig. 3 be the implantation material provided in an embodiment of the present invention for carrying radion main view (wherein sealing element does not show
Out);
Fig. 4 is the top view of the implantation material provided in an embodiment of the present invention for carrying radion;
Fig. 5 is the A-A cross-sectional view in Fig. 4;
Fig. 6 is the signal of the diamond lens structure of the implantation material provided in an embodiment of the present invention for carrying radion
Figure.
Icon: 100- prosthese;200- storage warehouse.
Specific embodiment
Technical solution of the present invention is clearly and completely described below in conjunction with attached drawing, it is clear that described implementation
Example is a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, ordinary skill
Personnel's every other embodiment obtained without making creative work, shall fall within the protection scope of the present invention.
In the description of the present invention, it is to be understood that, term " center ", " longitudinal direction ", " transverse direction ", " length ", " width ",
" thickness ", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outside", " up time
The orientation or positional relationship of the instructions such as needle ", " counterclockwise ", " axial direction ", " radial direction ", " circumferential direction " be orientation based on the figure or
Positional relationship is merely for convenience of description of the present invention and simplification of the description, rather than the device or element of indication or suggestion meaning must
There must be specific orientation, be constructed and operated in a specific orientation, therefore be not considered as limiting the invention.
In addition, term " first ", " second " are used for descriptive purposes only and cannot be understood as indicating or suggesting relative importance
Or implicitly indicate the quantity of indicated technical characteristic.Define " first " as a result, the feature of " second " can be expressed or
Implicitly include one or more of the features.In the description of the present invention, the meaning of " plurality " is two or more,
Unless otherwise specifically defined.
In the present invention unless specifically defined or limited otherwise, term " installation ", " connected ", " connection ", " fixation " etc.
Term shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or integral;It can be mechanical connect
It connects, is also possible to be electrically connected;It can be directly connected, can also can be in two elements indirectly connected through an intermediary
The interaction relationship of the connection in portion or two elements.It for the ordinary skill in the art, can be according to specific feelings
Condition understands the concrete meaning of above-mentioned term in the present invention.
The present invention is described in further detail below through specific implementation examples and in conjunction with the accompanying drawings.
With reference to shown in Fig. 1-Fig. 6:
Present embodiments provide a kind of implantation material that can carry radion, including prosthese 100, the more a sealing element;It is false
Multiple storage warehouses 200 are offered on body 100, storage warehouse 200 is for carrying radion, and sealing element is for blocking storage warehouse 200.
Before the use, medical worker can carry out tumor resection operation to patient, and then medical worker places prosthese 100
It is removed the position of tumour in patient, and offers multiple storage warehouses 200 on prosthese 100, when using prosthese 100, storage
Can there be radion in storehouse 200, and be sealed by opening of the sealing element to storage warehouse 200, after placing prosthese 100
To being sutured at patient incision;By opening up setting as storage warehouse 200 on prosthese 100, it can guarantee radion
Position will not fall off because of radion or dissociate and change, and guarantee that radion can radiate tumor locus
Treatment, will not damage other normal matrix.
Wherein, when needing using prosthese 100, radion (such as iodine-125) can first be placed on and open up by medical worker
In the storage warehouse 200 on prosthese 100, then storage warehouse 200 is sealed using sealing element, avoids radion from storage
It is backing out in storehouse 200, guarantee that radion can be steady in a long-term carries out radiotherapy to the position for needing radiotherapy, it will not
Because the activity of soft tissue causes radion to be detached from the body area that patient needs radiotherapy.
Specifically, the size of the storage warehouse 200 opened up on prosthese 100 are as follows: storage warehouse 200 is cylindrical, storage warehouse 200
Diameter is 1.5mm, and the length of storage warehouse 200 is 4mm, and the junction of the opening of storage warehouse 200 and 100 side wall of prosthese can be into
The processing of row fillet, avoids sharp edge from damaging the body tissue of patient's body.
Wherein, the edge of prosthese 100 will do it fillet processing, avoid the edge of prosthese 100 to the body of patient's body
Tissue damage.
It should be pointed out that radion uses iodine-125 radioactive isotope.
It wherein, is to be fixedly connected, including be detachably fixed connection and non-dismountable fixation between sealing element and storage warehouse 200
Connection, guarantees that the radion in storage warehouse 200 will not be detached under the premise of sealing element does not damage out of storage warehouse 200 with this
It goes out, to guarantee that radion, by the region of radiotherapy, the body of radiotherapy is needed to patient always situated in needs
Tissue carries out radiotherapy, can effectively avoid radion from dissociating to other body tissue positions, so that radion
Patient will not be damaged at other healthy body tissues.
It should be pointed out that the use scope of the implantation material provided in this embodiment for carrying radion is: medical matters people
During member carries out tumor resection to patient, after medical worker is by the tumor resection of patient's body, medical worker incite somebody to action this
The implantation material for carrying radion that embodiment provides is placed on the position that the original tumour of patient's body occupies, and passes through prosthese
Radion in 100 carries out radiotherapy to former tumor region.Implantation in this way can effectively realize axiolite
The implantation of son, without individually carrying out open surgery to patient, so that piercing method implantation radiation particle be avoided to make patient
At tissue damage.
Moreover, after radioactive particle is implanted into the patient with prosthese 100, particle steady operation in storage warehouse 200, effectively
Radion is reduced because of the risks such as fall off/dissociate caused by patient's body soft tissue, is not directly put particle in implantation process
Enter soft tissue, but be rationally arranged in pre-set position, can effectively realize the arrangement of internal particle, reduces and place hardly possible
Degree.
In the optinal plan of the present embodiment, prosthese 100 uses porous titanium framework.
Specifically, prosthese 100 uses POROUS TITANIUM supporting structure, prosthese 100 can satisfy using titanium alloy production prosthese 100
Be implanted into caused reaction after human body be in one can received level, while will not also cause the structure and performance of material
Qualitative change occurs, and 100 implantation material of prosthese of titanium alloy material can reduce or even avoid causing human body thin after being implanted into human body
The probability of the adverse effects such as allergy, inflammation and chemistry occurs for born of the same parents, blood and organ, and patient can reduce setting and avoid occurring to repel instead
The probability answered.Meanwhile titanium prosthesis 100 also meet be chronically implanted after still have good static mechanical property, i.e., it is enough
Intensity, suitable elasticity modulus, high stability, good corrosion resistance and durable wear-resistant.
In the optinal plan of the present embodiment, the internal void of porous titanium framework uses diamond lens structure.
It is formed as shown in figure 5, porous titanium framework is stacked by multiple diamond lens structures.Porous titanium framework passes through 3D printing
Technology production.
In the optinal plan of the present embodiment, the aperture of porous titanium framework is 640 μm (0.64mm).
Wherein, radion is cylindrical, and its both ends carries out fillet processing, and the length of radion is 3.5mm, diameter
For 1mm, the aperture of porous titanium framework is arranged to 640 μm (0.64mm), is opened up on porous titanium framework when radion is packed into
After in storage warehouse 200, the aperture of porous titanium framework is less than the diameter of radion, therefore it is pure excessively porous to can be avoided radion
The hole of titanium framework falls off away.
Specifically, porous titanium framework is made by 3D printing, and the base structure of porous titanium framework uses diamond crystalline lens
Structure.
Wherein, prosthese 100 uses porous titanium framework, facilitates radion to pass through prosthese 100 and carries out radiotherapy to patient.
It should be noted that the implantation material provided in this embodiment for carrying radion is used for the treatment of bone tumour, when
When medical worker cuts off the bone tumour of patient, the bone of patient's body can be cut off, be replaced at this time by prosthese 100 former
Bone reduces the influence to the normal work of subjects bones, and prosthese 100 can aid in prosthese 100 using porous structure
The elasticity modulus of elasticity modulus closer to skeleton (make elasticity modulus phase of the elasticity modulus of prosthese 100 with skeleton
When reduction even avoids generating the probability of stress shielding, reduces the atrophy for even avoiding body bone tissue, and raising prosthese 100 is planted
Enter successful probability, reduce and even avoid causing patient serious damage), and the prosthese 100 of porous structure facilitates people
The growth of body tissue enables the fixation of prosthese 100 stronger (growth of tissue further fixes prosthese 100).
It should be pointed out that prosthese 100 can be printed using titanium alloy (Ti6Al4V) metal.
In the optinal plan of the present embodiment, prosthese 100 is in cylindroid;Storage warehouse 200 is provided with the side wall of prosthese 100.It is false
The upper bottom surface of body 100 is the ellipse of major diameter 40mm, minor axis 30mm, and 100 height of prosthese is 50mm.
It may also be noted that the shape of prosthese 100 is not limited only to cylindroid, according to tumour production area and growth bone
Type, medical worker can the shape voluntarily to prosthese 100 be adjusted to adapt to actual use demand.
In the optinal plan of the present embodiment, 16 storage warehouses 200 are offered on prosthese 100, multiple storage warehouses 200 are average
It is divided into two groups of both ends that prosthese 100 is set.
In the optinal plan of the present embodiment, every group of storage warehouse 200 is uniformly arranged along the circumferential direction of prosthese 100.
In the optinal plan of the present embodiment, every group of storage warehouse 200 is respectively positioned in same plane.
In the optinal plan of the present embodiment, between the end face for the prosthese 100 that the central point of every group of storage warehouse 200 is adjacent to
Distance L be 2.75mm.
Wherein, micropore, the size and the size phase in 100 aperture of prosthese of micropore are offered in the internal side wall of storage warehouse 200
It together, is 640 μm.
Specifically, offering 16 storage warehouses 200 on the side wall of prosthese 100;16 storage warehouses 200 are divided into two groups
The both ends of prosthese 100 are set, and the distance between end face of every group of storage warehouse 200 and prosthese 100 is 2.75mm, it can be to trouble
(after bone tumour resection, the both ends for cutting away bone are connect with other body tissues, are controlled subsequent at both ends after person's excision bone tumour
When treatment, need to carry out radiotherapy to this both ends) carry out radiotherapy.
It should be pointed out that storage warehouse 200 is circumferentially uniformly arranged along prosthese 100, so that the exit dose of radion is uniform,
It avoids radion from concentrating radiation, the body tissue of patient part is damaged.
It may also be noted that every group of 8 storage warehouses 200 are provided with 100 outer wall of prosthese with 45 ° of isogonisms, and along prosthese
100 end on observation, there are the storage warehouses 200 that the axis of storage warehouse 200 is overlapped with the major diameter of elliptical cylinder-shape prosthese 100, meanwhile,
There are the storage warehouses 200 that the axis of storage warehouse 200 is overlapped with the minor axis of elliptical cylinder-shape prosthese 100.
Wherein guarantee that 4 implant cavities are located at long axis and short axle both ends on each face.
In the optinal plan of the present embodiment, sealing element uses bone wax.
Specifically, bone wax is made of 70% beeswax and the mixing of 30% vaseline, reduces and even avoid that human body is caused to damage
Evil.In the prior art, bone wax is common blocks marrow portion capillary oozing of blood, it can also be used to stop when various first-aid patients bone oozings of blood
Blood.Moreover, bone wax can be used for each all ages and classes, different parts, different reasons and the bone fracture that generates, sphenotresia or
When fragmentation when the oozing of blood of caused marrow portion capillary, it is used as hemostasis.Therefore using bone wax as the spacious of sealed storage storehouse 200
Mouth position, reduces and even avoids causing secondary injury to patient.
To sum up, by the way that radion and porous 100 structure of prosthese of 3D printing titanium alloy to be combined, clinical gold is realized
Belong to the functionalization of the prosthese 100 of material, and radiotherapy can greatly be increased in the effect of patient's body local location
Between and validity.The recurrence of local tumor after tumour patient tumor resection is performed the operation can greatly be slowed down, and without outer
Portion's radiotherapy avoids side reaction caused by body irradiation and the adverse effect to hepatic and renal function.
Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present invention., rather than its limitations;To the greatest extent
Pipe present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that: its according to
So be possible to modify the technical solutions described in the foregoing embodiments, or to some or all of the technical features into
Row equivalent replacement;And these are modified or replaceed, various embodiments of the present invention technology that it does not separate the essence of the corresponding technical solution
The range of scheme.
Claims (10)
1. the implantation material that one kind can carry radion characterized by comprising prosthese (100) and multiple sealing elements;
It is offered multiple storage warehouses (200) on the prosthese (100), the storage warehouse (200) is described for carrying radion
Sealing element is for blocking the storage warehouse (200).
2. the implantation material according to claim 1 for carrying radion, which is characterized in that the prosthese (100) uses
Porous titanium framework.
3. the implantation material according to claim 2 for carrying radion, which is characterized in that the porous titanium framework it is interior
Portion's hole uses diamond lens structure.
4. the implantation material according to claim 3 for carrying radion, which is characterized in that the hole of the porous titanium framework
Diameter is 640 μm.
5. the implantation material according to claim 1 for carrying radion, which is characterized in that the prosthese (100) is in ellipse
Cylinder;
The storage warehouse (200) is provided with the side wall of the prosthese (100).
6. the implantation material according to claim 5 for carrying radion, which is characterized in that opened on the prosthese (100)
Equipped with 16 storage warehouses (200), and the storage warehouse (200) is divided into two groups of settings in the prosthese (100)
Both ends.
7. the implantation material according to claim 6 for carrying radion, which is characterized in that storage warehouse described in every group
(200) circumferential direction along the prosthese (100) is uniformly arranged.
8. the implantation material according to claim 6 for carrying radion, which is characterized in that every group of the storage warehouse
(200) it is respectively positioned in same plane.
9. the implantation material according to claim 6 for carrying radion, which is characterized in that storage warehouse described in every group
(200) the distance between the end face of the prosthese (100) that central point is adjacent to L is 2.75mm.
10. -9 described in any item implantation materials for carrying radion according to claim 1, which is characterized in that the sealing
Part uses bone wax.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112472995A (en) * | 2020-12-07 | 2021-03-12 | 党松松 | Silicone stent with radioactive particles for department of respiration |
Citations (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6709379B1 (en) * | 1998-11-02 | 2004-03-23 | Alcove Surfaces Gmbh | Implant with cavities containing therapeutic agents |
CN2778233Y (en) * | 2004-07-30 | 2006-05-10 | 李鼎锋 | Artificial joint prosthesis with implanted radioactive source |
CN101161297A (en) * | 2007-11-21 | 2008-04-16 | 李楠 | Medical tectorial membrane shaped radiation NiTi alloy endovascular stent |
US20100137674A1 (en) * | 2008-11-26 | 2010-06-03 | David Evans | Brachytherapy treatment of the spine with irradiated implants |
CN102202644A (en) * | 2008-09-02 | 2011-09-28 | 巴特尔纪念研究院 | Brachytherapy seed with fast dissolving matrix for optimal delivery of radionuclides to cancer tissue |
CN102525696A (en) * | 2011-12-06 | 2012-07-04 | 常熟市碧溪新城特种机械厂 | Medical metal bracket |
CN102551934A (en) * | 2011-12-21 | 2012-07-11 | 毛宇 | Medical stent in radiotherapy and chemotherapy tracts |
CN203539496U (en) * | 2013-11-01 | 2014-04-16 | 巴格那 | Medical support |
CN203790087U (en) * | 2014-01-09 | 2014-08-27 | 刘阳 | Radioactive particle stent |
CN105030394A (en) * | 2015-07-24 | 2015-11-11 | 南京微创医学科技有限公司 | Device capable of carrying internal irradiation particles and manufacturing die and method of die |
CN205494666U (en) * | 2016-02-19 | 2016-08-24 | 张成武 | Iodine particle stomach tube of radiation therapy esophagus tumour |
CN107569766A (en) * | 2017-08-08 | 2018-01-12 | 天津赛德医药研究院有限公司 | A kind of radioactive particle support for cavity tumour Inner irradiation |
CN210583345U (en) * | 2019-05-27 | 2020-05-22 | 北京大学第三医院 | Implant capable of carrying radioactive particles |
-
2019
- 2019-05-27 CN CN201910448510.8A patent/CN110215600A/en active Pending
Patent Citations (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6709379B1 (en) * | 1998-11-02 | 2004-03-23 | Alcove Surfaces Gmbh | Implant with cavities containing therapeutic agents |
CN2778233Y (en) * | 2004-07-30 | 2006-05-10 | 李鼎锋 | Artificial joint prosthesis with implanted radioactive source |
CN101161297A (en) * | 2007-11-21 | 2008-04-16 | 李楠 | Medical tectorial membrane shaped radiation NiTi alloy endovascular stent |
CN102202644A (en) * | 2008-09-02 | 2011-09-28 | 巴特尔纪念研究院 | Brachytherapy seed with fast dissolving matrix for optimal delivery of radionuclides to cancer tissue |
US20100137674A1 (en) * | 2008-11-26 | 2010-06-03 | David Evans | Brachytherapy treatment of the spine with irradiated implants |
CN102525696A (en) * | 2011-12-06 | 2012-07-04 | 常熟市碧溪新城特种机械厂 | Medical metal bracket |
CN102551934A (en) * | 2011-12-21 | 2012-07-11 | 毛宇 | Medical stent in radiotherapy and chemotherapy tracts |
CN203539496U (en) * | 2013-11-01 | 2014-04-16 | 巴格那 | Medical support |
CN203790087U (en) * | 2014-01-09 | 2014-08-27 | 刘阳 | Radioactive particle stent |
CN105030394A (en) * | 2015-07-24 | 2015-11-11 | 南京微创医学科技有限公司 | Device capable of carrying internal irradiation particles and manufacturing die and method of die |
CN205494666U (en) * | 2016-02-19 | 2016-08-24 | 张成武 | Iodine particle stomach tube of radiation therapy esophagus tumour |
CN107569766A (en) * | 2017-08-08 | 2018-01-12 | 天津赛德医药研究院有限公司 | A kind of radioactive particle support for cavity tumour Inner irradiation |
CN210583345U (en) * | 2019-05-27 | 2020-05-22 | 北京大学第三医院 | Implant capable of carrying radioactive particles |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112472995A (en) * | 2020-12-07 | 2021-03-12 | 党松松 | Silicone stent with radioactive particles for department of respiration |
CN112472995B (en) * | 2020-12-07 | 2022-08-12 | 杨云伟 | Silicone stent with radioactive particles for department of respiration |
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