CN109173092A - It is a kind of easily from the Inner irradiation device taken out in vivo - Google Patents

It is a kind of easily from the Inner irradiation device taken out in vivo Download PDF

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Publication number
CN109173092A
CN109173092A CN201811113584.8A CN201811113584A CN109173092A CN 109173092 A CN109173092 A CN 109173092A CN 201811113584 A CN201811113584 A CN 201811113584A CN 109173092 A CN109173092 A CN 109173092A
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CN
China
Prior art keywords
medical material
material pipe
taken out
vivo
radioactive source
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Pending
Application number
CN201811113584.8A
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Chinese (zh)
Inventor
阎尔坤
白红升
白鹏飞
朱辉
李佳
苗永涛
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tianjin Co Ltd Of Saden Medicine Research Academy
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Tianjin Co Ltd Of Saden Medicine Research Academy
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Priority to CN201811113584.8A priority Critical patent/CN109173092A/en
Publication of CN109173092A publication Critical patent/CN109173092A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1007Arrangements or means for the introduction of sources into the body

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)

Abstract

The invention discloses one kind easily from the Inner irradiation device taken out in vivo, including medical material pipe, radioactive source and spacer is provided in medical material pipe, the number of spacer is 1 more than radioactive source, the invention has the benefit that easy to operate, operating time is short;It realizes accurate positioning of the radioactive source in tumour, avoids the variation for influencing source positions because of organ activity;Falling off or migrating for radioactive source is avoided, side effect, good effect are reduced;After treatment, it can facilitate and take out radioactive source in slave body, noresidue reduces the unnecessary irradiation of normal tissue, reduces side reaction;It keeps organ complete and function perfects.

Description

It is a kind of easily from the Inner irradiation device taken out in vivo
Technical field
The invention belongs to the field of medical instrument technology, are related to one kind easily from the Inner irradiation device taken out in vivo.
Background technique
Malignant tumour, which has become, a kind of seriously threatens human health and common multiple disease.Currently, radiotherapy becomes One of the three big main means for treating tumour.When radiotherapy mainly penetrates tissue using ray, normal tissue and tumour Cell controls difference biological respinse mechanism caused by radioactive ray the growth and proliferation for the treatment of tumour cell.With operative treatment It is compared with chemotherapy, radiotherapy can retain the function of treated organ, and treatment side effect is small, can effectively ensure that patient is cured Life quality afterwards.
Radioactive prospecting instrument tumour is subjected to internal radiotherapy, also known as brachytherapy is percutaneous or art in lead to Implant needle or implanting device are crossed by a certain number of radioactive source implantation tumours position, the ray issued using radioactive source is for a long time to swollen The irradiation of oncocyte, killing or kill tumour cell, to achieve the purpose that treatment.The treatment technology is widely using various The implanted treatment of entity tumor, achieves good therapeutic effect.It is excellent that this method has that curative effect is high, easy to operate and wound is small etc. Point.But there is also some disadvantages for this method (radioactivity Implantation in Treating), as influenced after (1) implantation because of organ activity Source positions and arrangement cause dosage distribution to change, influence therapeutic effect;(2) falling off or migrate there are radioactive source;(3) Radioactive source stays in the body, and is not easily taken out after treatment, to patient at heart or body brings certain burden;(4) clinical manipulation phase To complexity, operating time is long.These disadvantages, what is showed in the treatment of head and neck neoplasm, superficial tumor and breast cancer etc. is brighter It is aobvious.
Summary of the invention
The purpose of the present invention is overcoming the prior art, one kind is provided and is mainly used for treating hand, foot, ear, tongue, nose The shallower tumour such as chamber, incidence, mammary gland, easy to operate, structure is simple, good effect, easily from the Inner irradiation device taken out in vivo.
Technical solution of the present invention is summarized as follows:
It is a kind of easily from the Inner irradiation device taken out in vivo, including medical material pipe 1, radiation is provided in medical material pipe 1 Source 2 and spacer 3, the number of spacer is 1 more than radioactive source.
The internal diameter of medical material pipe 1 is 0.3mm~2mm, and length is 10mm~1000mm.
Medical material is gold, silver, platinum, tantalum, niobium, zirconium, medical stainless steel, medical titanium, medical titanium alloy, Co-Cr-Mo conjunction Gold, gathers Co-Ni-Cr-Mo alloy, niti-shaped memorial alloy, polyether-polyurethane, polytetrafluoroethylene (PTFE), silicon rubber, polyester, nylon Methyl methacrylate, polyvinyl chloride, polyethylene, polypropylene, polystyrene, polyvinyl alcohol, poly(aryl ether ketone) or nonabsorable seam Zygonema.
The number of radioactive source 2 is 1, and spacer 3 is located at the both ends of medical material pipe 1.
The number of radioactive source 2 be 2~15, spacer 3 be located at medical material pipe 1 both ends and two-by-two radioactive source 2 it Between.
The material of spacer 3 is gold, silver, platinum, tantalum, niobium, zirconium, iron, copper, stainless steel, titanium, titanium alloy, aluminium alloy, magnesium conjunction Gold, polyurethane, polyether-polyurethane, polytetrafluoroethylene (PTFE), polyester, nylon, polymethyl methacrylate, polyvinyl chloride, gathers silicon rubber Ethylene, polypropylene, polystyrene, polyvinyl alcohol, poly(aryl ether ketone), polyvinylpyrrolidone, it is poly bis to carboxylate phenoxy propene, it is bright Glue or human serum albumins.
Preferably, 1 both ends of medical material pipe pass through welding, bonding mode sealing.
The both ends of medical material pipe 1 are flexibly connected with fixing clamp, snak link or button.
The invention has the benefit that (1) is easy to operate, operating time is short;(2) realize that radioactive source is accurate in tumour Positioning, avoids the variation that source positions are influenced because of organ activity;(3) falling off or migrating for radioactive source is avoided, is reduced secondary Effect, good effect;(4) after treating, it can facilitate and take out radioactive source in slave body, noresidue reduces the unnecessary of normal tissue Irradiation, reduces side reaction;It keeps organ complete and function perfects.
Detailed description of the invention
Fig. 1 is a kind of the schematic diagram of the section structure (medical material that center line is easily crossed from the Inner irradiation device taken out in vivo of the present invention The both ends of expects pipe (1) seal).
Fig. 2 is the structural schematic diagram of snak link.
Fig. 3 is the structural schematic diagram of fixing clamp.
Fig. 4 is present invention one kind easily from the implanting state schematic diagram of the Inner irradiation device taken out in vivo.
Specific embodiment
The present invention will be further described below with reference to the drawings.
It is a kind of easily from the Inner irradiation device (see Fig. 1) taken out in vivo, including medical material pipe 1, be arranged in medical material pipe 1 There are radioactive source 2 and spacer 3, the number of spacer is 1 more than radioactive source.
1 internal diameter of medical material pipe is preferably 0.85mm, can also select the arbitrary number in 0.3mm~2mm, such as 0.3mm, 0.5mm, 0.8mm, 1.2mm, 2mm etc..
Length is preferably 60mm, can also select the arbitrary number in 10mm~1000mm, such as 10mm, 50mm, 80mm, 100mm, 150mm, 300mm, 500mm, 1000mm etc..
Medical material is preferably niti-shaped memorial alloy, and gold, silver, platinum, tantalum, niobium, zirconium, 316L can also be selected medical stainless Steel, 304 medical stainless steels, commercial pure titanium, medical TC4 titanium alloy, Co-Cr-Mo alloy, Co-Ni-Cr-Mo alloy, Ti-15Mo Titanium alloy, TNTZ alloy, Ti2448, food-grade polyether-polyurethane, food-grade polytetrafluoroethylene (PTFE), silicon rubber, polyester, nylon, food Grade polymethyl methacrylate, polyvinyl chloride, polyethylene, polypropylene, polystyrene, polyvinyl alcohol or nonabsorable suture Line.
The number of radioactive source 2 can also be 1, and spacer 3 is located at the both ends of medical material pipe 1.
The number of radioactive source can also be any of 2~15, e.g., 2,3,5,8,15 etc., spacer 3 Positioned at the both ends of medical material pipe 1 and two-by-two between radioactive source 2.
The material of spacer 3 is preferably silicon rubber, can also select gold, silver, platinum, tantalum, niobium, zirconium, 316L medical stainless steel, 304 medical stainless steels, commercial pure titanium, medical TC4 titanium alloy, Co-Cr-Mo alloy, Co-Ni-Cr-Mo alloy, Ti-15Mo titanium close Gold, TNTZ alloy, Ti2448, aluminium alloy, magnesium alloy, silicon rubber, polyurethane, food-grade polyether-polyurethane, food-grade polytetrafluoro Ethylene, polyester, nylon, food is grade polymethylmethacrylacontinuous, polyvinyl chloride, polyethylene, polypropylene, polystyrene, polyethylene It is alcohol, poly(aryl ether ketone), polyvinylpyrrolidone, poly bis to carboxylate phenoxy propene, gelatin or human serum albumins.
The both ends of medical material pipe 1 can also pass through glued seals by welding encapsulation.
Medical material pipe is flexibly connected with fixing clamp, snak link or button.
Radioactive source 2 is iodine-125, palladium -103, Radium-224, cesium-131, Iridium-192 source, ytterbium -169, phosphorus -32 and Yttrium-90.It is preferred that For iodine-125, palladium -103, Radium-224, cesium-131.
Medical material pipe is circle perpendicular to the section configuration of long axis, oval, rectangle or other geometry polygons, but is examined Consider the impression and applicability of patient, section is preferably circular.
A series of holes of different shapes or lines can be set on the outer wall of medical material pipe, it is contemplated that this hair of applicability Bright not set relevant hole or lines.
The fixing clamp being flexibly connected with the end of medical material pipe, snak link or button are commercially available.Including different geometric forms Shape, it is contemplated that the applicability present invention uses snak link.
The operating process that radioactive source is put into a kind of Inner irradiation device device easily taken out is as follows:
Radioactive source and spacer are successively implanted into medical material pipe by implanting device or implanting gun, between the implantation of both ends After parting, encapsulated by the method for welding.
A kind of use of the Inner irradiation device device (abbreviation radiotheraphy device) easily taken out is (for treating hand, foot, ear, tongue, nose The shallower tumour such as chamber, incidence, mammary gland):
Quantity and the position that radiotheraphy device is placed needed for determining according to patient tumors size, see Fig. 4, radiotheraphy device are placed in In implant needle or implanting device, after passing through tumour and skin with implant needle or implanting device, radiotheraphy device is released with push rod, passes through pulling The position of the medical material pipe adjustment radioactive source of radiotheraphy device, extracts implant needle or implanting device out, (can also use spring with fixing clamp Button or button) the exposed both ends in extracutaneous medical material pipe 1 are fixed, carry out radiotherapy.After treatment end, consolidating for one end is removed Clamp (snak link or button), pulls out radiotheraphy device from the other end.
The above content is illustrate the specific embodiment party, and it cannot be said that of the invention to what the present invention was done in conjunction with the embodiments Formula is only limitted to these explanations.For general technical staff of the technical field of the invention, present inventive concept is not being departed from Under the premise of, several simple deductions and transformation can also be made, all shall be regarded as belonging to protection scope of the present invention.

Claims (8)

1. one kind is easily from the Inner irradiation device taken out in vivo, it is characterized in that including medical material pipe (1), in medical material pipe (1) It is provided with radioactive source (2) and spacer (3), the number of spacer is 1 more than radioactive source.
2. it is according to claim 1 easily from the Inner irradiation device taken out in vivo, it is characterized in that the medical material pipe (1) is interior Diameter is 0.3mm~2mm, and length is 10mm~1000mm.
3. according to claim 1 easily from the Inner irradiation device taken out in vivo, it is characterized in that the medical material be gold, silver, Platinum, tantalum, niobium, zirconium, medical stainless steel, medical titanium, medical titanium alloy, Co-Cr-Mo alloy, Co-Ni-Cr-Mo alloy, NiTi shape Shape memory alloys, polyether-polyurethane, polytetrafluoroethylene (PTFE), silicon rubber, polyester, nylon, polymethyl methacrylate, polyvinyl chloride, Polyethylene, polypropylene, polystyrene, polyvinyl alcohol, poly(aryl ether ketone) or nonabsorable suture.
4. it is according to claim 1 easily from the Inner irradiation device taken out in vivo, it is characterized in that the number of the radioactive source (2) is 1, spacer 3 is located at the both ends of medical material pipe (1).
5. it is according to claim 1 easily from the Inner irradiation device taken out in vivo, it is characterized in that the number of the radioactive source (2) is 2~15, spacer 3 is located at the both ends of medical material pipe (1) and two-by-two between radioactive source (2).
6. it is according to claim 1, easy from the Inner irradiation device taken out in vivo described in 4 or 5, it is characterized in that the spacer (3) Material is gold, silver, platinum, tantalum, niobium, zirconium, iron, copper, stainless steel, titanium, titanium alloy, aluminium alloy, magnesium alloy, silicon rubber, polyurethane, gathers Ether polyurethane, polytetrafluoroethylene (PTFE), polyester, nylon, polymethyl methacrylate, polyvinyl chloride, polyethylene, polypropylene, polyphenyl second It is alkene, polyvinyl alcohol, poly(aryl ether ketone), polyvinylpyrrolidone, poly bis to carboxylate phenoxy propene, gelatin or human serum albumins.
7. it is easy from the Inner irradiation device taken out in vivo described in one of -5 according to claim 1, it is characterized in that the medical material pipe (1) both ends pass through welding, bonding mode sealing, the both ends and fixing clamp of medical material pipe (1), the activity of snak link or button Connection.
8. it is according to claim 6 easily from the Inner irradiation device taken out in vivo, it is characterized in that the two of the medical material pipe (1) By welding, bonding mode sealing, the both ends of medical material pipe (1) are flexibly connected with fixing clamp, snak link or button for end.
CN201811113584.8A 2018-09-25 2018-09-25 It is a kind of easily from the Inner irradiation device taken out in vivo Pending CN109173092A (en)

Priority Applications (1)

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Application Number Priority Date Filing Date Title
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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1761500A (en) * 2003-03-17 2006-04-19 医疗物理有限公司 Products and methods for brachytherapy
CN204170122U (en) * 2014-03-31 2015-02-25 张福君 Magnesium-alloy tube is threaded radioactive particle chain
CN105920727A (en) * 2016-04-11 2016-09-07 王娟 Radioactive particle chain and use method thereof
CN106823121A (en) * 2017-01-24 2017-06-13 原子高科股份有限公司 A kind of degradable radioactive particle chain with shape memory function

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1761500A (en) * 2003-03-17 2006-04-19 医疗物理有限公司 Products and methods for brachytherapy
CN204170122U (en) * 2014-03-31 2015-02-25 张福君 Magnesium-alloy tube is threaded radioactive particle chain
CN105920727A (en) * 2016-04-11 2016-09-07 王娟 Radioactive particle chain and use method thereof
CN106823121A (en) * 2017-01-24 2017-06-13 原子高科股份有限公司 A kind of degradable radioactive particle chain with shape memory function

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Application publication date: 20190111

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