CN204170122U - Magnesium-alloy tube is threaded radioactive particle chain - Google Patents
Magnesium-alloy tube is threaded radioactive particle chain Download PDFInfo
- Publication number
- CN204170122U CN204170122U CN201420152981.7U CN201420152981U CN204170122U CN 204170122 U CN204170122 U CN 204170122U CN 201420152981 U CN201420152981 U CN 201420152981U CN 204170122 U CN204170122 U CN 204170122U
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- Prior art keywords
- magnesium
- radioactive particle
- particle
- particle chain
- alloy
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- 239000002245 particle Substances 0.000 title claims abstract description 67
- 229910000861 Mg alloy Inorganic materials 0.000 title claims abstract description 42
- 230000002285 radioactive effect Effects 0.000 title claims abstract description 40
- 206010028980 Neoplasm Diseases 0.000 abstract description 18
- 238000006073 displacement reaction Methods 0.000 abstract description 6
- 238000002513 implantation Methods 0.000 abstract description 5
- 238000000034 method Methods 0.000 abstract description 4
- 230000002980 postoperative effect Effects 0.000 abstract description 4
- 230000008569 process Effects 0.000 abstract description 4
- 239000011777 magnesium Substances 0.000 description 11
- 239000000956 alloy Substances 0.000 description 9
- 229910045601 alloy Inorganic materials 0.000 description 8
- 229910052749 magnesium Inorganic materials 0.000 description 8
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 7
- 230000015556 catabolic process Effects 0.000 description 5
- 238000006243 chemical reaction Methods 0.000 description 5
- 238000006731 degradation reaction Methods 0.000 description 5
- 210000001519 tissue Anatomy 0.000 description 5
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 238000001727 in vivo Methods 0.000 description 4
- 230000005855 radiation Effects 0.000 description 4
- 238000011160 research Methods 0.000 description 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 3
- 229910019440 Mg(OH) Inorganic materials 0.000 description 3
- PNDPGZBMCMUPRI-XXSWNUTMSA-N [125I][125I] Chemical compound [125I][125I] PNDPGZBMCMUPRI-XXSWNUTMSA-N 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 210000000988 bone and bone Anatomy 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 229910052739 hydrogen Inorganic materials 0.000 description 3
- 239000001257 hydrogen Substances 0.000 description 3
- 210000003734 kidney Anatomy 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- 206010057248 Cell death Diseases 0.000 description 2
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 description 2
- 229910001069 Ti alloy Inorganic materials 0.000 description 2
- 230000005856 abnormality Effects 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 2
- 230000009089 cytolysis Effects 0.000 description 2
- 230000003013 cytotoxicity Effects 0.000 description 2
- 231100000135 cytotoxicity Toxicity 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 229940044173 iodine-125 Drugs 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 229910001425 magnesium ion Inorganic materials 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 238000010827 pathological analysis Methods 0.000 description 2
- 201000001514 prostate carcinoma Diseases 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 1
- 229910001316 Ag alloy Inorganic materials 0.000 description 1
- 208000018084 Bone neoplasm Diseases 0.000 description 1
- 206010006187 Breast cancer Diseases 0.000 description 1
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- 201000009030 Carcinoma Diseases 0.000 description 1
- 208000005189 Embolism Diseases 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 208000009849 Female Genital Neoplasms Diseases 0.000 description 1
- 208000032612 Glial tumor Diseases 0.000 description 1
- 206010018338 Glioma Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 1
- 229910001051 Magnalium Inorganic materials 0.000 description 1
- 206010027476 Metastases Diseases 0.000 description 1
- 208000002454 Nasopharyngeal Carcinoma Diseases 0.000 description 1
- 206010061306 Nasopharyngeal cancer Diseases 0.000 description 1
- 206010057444 Oropharyngeal neoplasm Diseases 0.000 description 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 description 1
- 206010035603 Pleural mesothelioma Diseases 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 201000000582 Retinoblastoma Diseases 0.000 description 1
- 235000018259 Solanum vestissimum Nutrition 0.000 description 1
- 240000002825 Solanum vestissimum Species 0.000 description 1
- 208000001435 Thromboembolism Diseases 0.000 description 1
- 206010043966 Tongue neoplasm malignant stage unspecified Diseases 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- QCWXUUIWCKQGHC-UHFFFAOYSA-N Zirconium Chemical compound [Zr] QCWXUUIWCKQGHC-UHFFFAOYSA-N 0.000 description 1
- PGTXKIZLOWULDJ-UHFFFAOYSA-N [Mg].[Zn] Chemical class [Mg].[Zn] PGTXKIZLOWULDJ-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 239000012736 aqueous medium Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 201000003433 benign pleural mesothelioma Diseases 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 201000008275 breast carcinoma Diseases 0.000 description 1
- 210000005178 buccal mucosa Anatomy 0.000 description 1
- ZFXVRMSLJDYJCH-UHFFFAOYSA-N calcium magnesium Chemical class [Mg].[Ca] ZFXVRMSLJDYJCH-UHFFFAOYSA-N 0.000 description 1
- 208000025183 carcinoma of floor of mouth Diseases 0.000 description 1
- 238000006555 catalytic reaction Methods 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000002059 diagnostic imaging Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- PCHJSUWPFVWCPO-OUBTZVSYSA-N gold-198 Chemical compound [198Au] PCHJSUWPFVWCPO-OUBTZVSYSA-N 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 229910052740 iodine Inorganic materials 0.000 description 1
- 239000011630 iodine Substances 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- GCICAPWZNUIIDV-UHFFFAOYSA-N lithium magnesium Chemical class [Li].[Mg] GCICAPWZNUIIDV-UHFFFAOYSA-N 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- KBMLJKBBKGNETC-UHFFFAOYSA-N magnesium manganese Chemical class [Mg].[Mn] KBMLJKBBKGNETC-UHFFFAOYSA-N 0.000 description 1
- -1 magnesium rare earth metal Chemical class 0.000 description 1
- SJCKRGFTWFGHGZ-UHFFFAOYSA-N magnesium silver Chemical compound [Mg].[Ag] SJCKRGFTWFGHGZ-UHFFFAOYSA-N 0.000 description 1
- QRNPTSGPQSOPQK-UHFFFAOYSA-N magnesium zirconium Chemical class [Mg].[Zr] QRNPTSGPQSOPQK-UHFFFAOYSA-N 0.000 description 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- 238000010297 mechanical methods and process Methods 0.000 description 1
- 230000005226 mechanical processes and functions Effects 0.000 description 1
- 206010027191 meningioma Diseases 0.000 description 1
- 230000009401 metastasis Effects 0.000 description 1
- 230000001394 metastastic effect Effects 0.000 description 1
- 206010061289 metastatic neoplasm Diseases 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 210000004165 myocardium Anatomy 0.000 description 1
- 201000011216 nasopharynx carcinoma Diseases 0.000 description 1
- 208000018389 neoplasm of cerebral hemisphere Diseases 0.000 description 1
- 230000002232 neuromuscular Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 201000006958 oropharynx cancer Diseases 0.000 description 1
- KDLHZDBZIXYQEI-OIOBTWANSA-N palladium-103 Chemical compound [103Pd] KDLHZDBZIXYQEI-OIOBTWANSA-N 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 238000001243 protein synthesis Methods 0.000 description 1
- 229910052761 rare earth metal Inorganic materials 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 208000008732 thymoma Diseases 0.000 description 1
- 230000014616 translation Effects 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052726 zirconium Inorganic materials 0.000 description 1
Abstract
This utility model relates to a kind of magnesium-alloy tube and connects radioactive particle chain, and it is made up of radioactive particle (bolt), magnesium-alloy tube (nut).There is screw thread in radioactive particle two end surfaces, its screw thread form, size and magnesium alloy pipe box two ends thread in inner cavity are coincide.Hand of spiral is right-handed thread, and the flat shape of screw thread can be triangle, rectangle, trapezoidal or zigzag.The each unit junction of this utility model particle chain possesses the features such as tight, firm, the mechanical performance of the excellence utilizing magnesium alloy to possess, can ensure that the particle chain connected is implanted conveniently in the process of Operation, shorten operating time, in art or each unit of postoperative particle chain can not there is slippage, displacement.Magnesium-alloy tube biological safety is high, and has controlled biological degradability, and these bring great safety and convenience all to seeds implantation tumor.
Description
Technical field
This utility model relates to a kind of medical equipment, is specifically related to a kind of radioactive particle chain connected in a specific way.
Background technology
Radioactive particle tissue space implantation treatment malignant tumor is the design of appliance computer stereoscopic localized planning system (TPS), modern medicine iconography guide under by invasive manner by radioactive particle according in tumor size, form implantation tumour or by tumor-infiltrated infringement tissue in, lasting, short-range lonizing radiation are sent by mini-radioactive resource, tumor tissues is made to suffer farthest to kill and wound, and normal structure is not damaged or only have microlesion, finally reach the object for the treatment of tumor.Because seeds implanted treatment has, wound is little, irradiation at short distance is highly conformal, and the features such as damaging surrounding tissue is little, therefore this Therapeutic Method is paid attention to clinically gradually.But radioactive particle many uses titanium alloy is as Package casing at present, smooth surface, and volume is short and small, displacement and migration easily occurs, causes tumor area local radiation DM, displacement even at a distance causes organ thromboembolism, needs second operation to be taken out time serious.Document is reported for work after carcinoma of prostate radioactive prospecting instrument, and the incidence rate that particle is displaced to lung reaches 17% ~ 18%.And in the actual mechanical process of seeds implanted operation, be often difficult to keep the distance between the linear array of particle and particle, particle dose distributed very uneven, have impact on the overall curative effect of the close-range treatment of clinical radiation particle.The socket of previously passed port and the particle chain that forms, owing to being socketed the limitation of mode, radioactive particle chain in operative process or after implanting due to body movement cause particle chain to depart from, dispersion.The each unit of this utility model radioactive particle chain is threaded connection, there is the features such as firm, tight, can ensure connect particle chain in the process of Operation or each unit of postoperative particle chain can not there is slippage, displacement, the particle chain of more previously passed socket mode has significant superiority.
Magnesium is the nutrient of needed by human, is the intracellular cation being only second to potassium, sodium, calcium in human body, total amount about more than 20 gram in human body.Participate in protein synthesis, energy catalysis and the sharp in vivo enzyme of clock more than 300 system, regulate the activity of neuromuscular and central nervous system, ensure myocardium normal contraction, almost participate in all metabolic processes in human body.From in recent ten years both at home and abroad the report of each side to Mg-based hydrogen storage be not difficult to find, magnesium, as medical embedded material, compared with having dropped into now the various metal implant materials of Clinical practice, has had following outstanding advantage; 1. aboundresources, cheap; 2. biological controlled degradation; 3. good biocompatibility, there is chemical reaction and change magnesium ion in magnesium, magnesium ion carrys out adjustment by the metabolism of the absorption in body and kidney, thus magnesium alloy materials is degraded and absorbed in vivo gradually in aqueous medium.Preliminary Study of cytotoxicity shows: magnesium does not have inhibitory action for the growth of medullary cell, does not also find cytolysis phenomenon.Rat et al. Ke Mg-based hydrogen storage test display rat biochemical indicator has no obvious fluctuation, and liver, kidney pathological analysis show no obvious abnormalities.
Summary of the invention
The purpose of this utility model is to overcome the deficiencies in the prior art part, provides a kind of radioactive particle chain connected mode, and each unit junction of made particle chain possesses closely, firm.The risk of the dose distribution inequality existed during for making up the single seeds implantation tumor used clinically at present or the postoperative each particle cell slippage displacement of conventional particle chain.
The purpose of this utility model is achieved in that
Magnesium-alloy tube connects radioactive particle chain and is made up of radioactive particle (1), magnesium alloy sleeve pipe (2), by arranging external screw thread (3) at radioactive particle (1) two end surfaces, magnesium alloy sleeve pipe (2) two ends surface of internal cavity arranges female thread (4), internal and external threads mates identical mutually, be tightened, make magnesium alloy sleeve pipe (2) be able to each radioactive particle to connect into particle chain.
Radioactive particle described in the utility model is the radionuclide that metal is sealed by shell, and what this metal was used at present by shell mostly is titanium alloy, and radionuclide can be iodine-125, gold-198 and palladium-103.
Described magnesium alloy sleeve pipe 2 for content of magnesium be greater than 80% magnalium series alloy, magnesium zinc series alloy, magnesium manganese series alloy, magnesium calcium series alloy, magnesium zirconium series alloy, magnesium rare earth metal alloy, the binary that is a kind of or that be made up of these systems of magnesium Silver Alloys or magnesium lithium series alloy, ternary or polynary system magnesium alloy.
Advantage of the present invention and beneficial effect are:
1, the particle chain made by the present invention, its each unit is threaded connection, there is the features such as firm, tight, the mechanical performance of the excellence utilizing magnesium alloy to possess, can ensure that the particle chain connected is implanted conveniently in the process of Operation, shorten operating time, in art or each unit of postoperative particle chain can not there is slippage, displacement.
2, the magnesium alloy biological safety of the present invention's employing is high, in alloy, main component is magnesium, other compositions comprise the element that zinc, manganese, calcium, aluminum, zirconium etc. mostly are needed by human, in addition may containing inevitable impurity because of content very micro-, also almost nil to the harm of human body.Preliminary Study of cytotoxicity shows: magnesium does not have inhibitory action for the growth of medullary cell, does not also find cytolysis phenomenon.Rat et al. Ke Mg-based hydrogen storage test display: observe 18 weeks, rat biochemical indicator has no obvious fluctuation, and liver, kidney pathological analysis show no obvious abnormalities.
3, the magnesium alloy that the present invention adopts has controlled biological degradability, and magnesium alloy in aqueous following reaction can occur:
2Mg → 2Mg
++ 2e(anode reaction)
Mg
++2OH
－→Mg（OH）
2
2H
++ 2e → H2(cathode reaction)
2H
2O+2e→2OH－+H
2
Due to Mg(OH)
2protective effect very weak, particularly containing in the solution of chloride ion, the Mg(OH on surface)
2following reaction can be there is by Chloride Attack:
Mg（OH）
2+Cl→MgCl
2+2OH
－
Therefore magnesium alloy is easy to be corroded in the solution of chloride ion-containing.Because containing a large amount of chloride ion in human body, therefore magnesium alloy is at people's physical ability fast degradation, and research shows that magnesium alloy in vivo about 2 months can be degradable.
Current magnesium alloy mainly concentrates on degradable blood vessel bracket, degradable bone peg, bone suture in the research in medical, the armarium of artificial bone.In this regard, forefathers have done large quantifier elimination to reduce the corrosivity of magnesium alloy; But accelerate the corrosion of magnesium alloy, to shorten the research of magnesium alloy degradation time in vivo, there is not been reported.The present invention is by the adjustment composition of magnesium alloy and the ratio of each composition, make magnesium alloy accelerated degradation, make its degradation time remain on 10 ~ 40 days, and controlled, reaching decays with nuclide emission mates, and finally makes the spacing of radioactive particle reduce gradually while tumor regression.
4, the present invention brings great convenience will to seeds implantation tumor clinically, greatly can shorten operating time, thus reduce the time of medical personnel and radionuclide close contact, reduce medical personnel's radiation dose.
Accompanying drawing explanation
Fig. 1: radioactive particle structure chart;
Fig. 2: magnesium alloy sleeve structure figure;
Fig. 3: radioactive particle chain structural representation.
Detailed description of the invention
Magnesium-alloy tube connects radioactive particle chain and is made up of radioactive particle (1), magnesium alloy sleeve pipe (2), it is characterized in that radioactive particle (1) two end surfaces arranges external screw thread (3), magnesium alloy sleeve pipe (2) two ends surface of internal cavity arranges female thread (4), internal and external threads mates identical mutually, be tightened, each radioactive particle is connected into particle chain by magnesium alloy sleeve pipe (2).Equidistant arrangement between radioactive particle (1).
The body outer diameter of radioactive particle (1) is 0.8mm, and particle length can be 5.0 ~ 8.0mm, and one-sided screw thread scope is 1.0 ~ 2.0mm, and side major diameter of thread is 0.6 ~ 0.8mm; Magnesium alloy sleeve pipe (2) external diameter is 0.8 ~ 1.0mm, wall thickness 0.2mm, length 5.0 ~ 8.0mm.Radioactive particle (1) two ends thread surface pitch 0.1 ~ 0.2mm, hand of spiral is right-handed thread, and the flat shape of screw thread can be triangle, rectangle, trapezoidal or zigzag.
Be total length by particle design be 5.0 ~ 8.0mm, one-sided screw thread scope is 1.0 ~ 2.0mm, and largest tube external diameter is 0.8mm, and its two side ends surface exists screw thread (as Fig. 1).And magnesium-alloy tube (nut) (as Fig. 2) that design and sealing have iodine particle (bolt) the two ends screw thread form of radionuclide to match, be threaded by both, make the radioactive particle chain (as Fig. 3) of certain length.In operation, the particle chain made is loaded the implanting gun of coupling, be implanted under the guiding of medical imaging device in tumor tumor body by preoperative plan.The half-life of radioactivity iodine-125 is 60 days, shows through a large amount of clinical research, in after implanting tumor body 10 ~ 40 days of radioactivity I-125 seeds to tumor to kill and wound benefit maximum.
The present invention can substitute original single radioactive particle, is widely used in the cerebral tumor can not opening cranium; Need to retain important functional tissue or perform the operation and will involve the tumor of vitals; Cannot the primary tumo(u)r of excision; To the insensitive entity tumor of chemotherapy; External exposure poor effect or underdosage, the local dose as external exposure supplements.The disease kind of the treatment that suitable particle chain is implanted is very extensive, comprises cerebral glioma, metastatic encephaloma, meningioma; Nasopharyngeal carcinoma, orbital internal tumor, retinoblastoma, oropharynx cancer, carcinoma of tongue, carcinoma of floor of mouth, carcinoma of buccal mucosa; Cervical metastasis; Pulmonary carcinoma, thymoma, mesothelioma of pleura, breast carcinoma; Cancer of pancreas, cancer of biliary duct, hepatocarcinoma; Carcinoma of prostate, gynecological tumor; Bone tumor.
Claims (4)
1. a magnesium-alloy tube connects radioactive particle chain, be made up of radioactive particle (1), magnesium alloy sleeve pipe (2), it is characterized in that radioactive particle (1) two end surfaces arranges external screw thread (3), magnesium alloy sleeve pipe (2) two ends surface of internal cavity arranges female thread (4), internal and external threads mates identical mutually, be tightened, each radioactive particle is connected into particle chain by magnesium alloy sleeve pipe (2).
2. magnesium-alloy tube according to claim 1 connects radioactive particle chain, it is characterized in that equidistant arrangement between radioactive particle (1).
3. magnesium-alloy tube according to claim 1 connects radioactive particle chain, it is characterized in that the body outer diameter of radioactive particle (1) is 0.8mm, particle length is 5.0 ~ 8.0mm, and one-sided screw thread scope is 1.0 ~ 2.0mm, and side major diameter of thread is 0.6 ~ 0.8mm; Magnesium alloy sleeve pipe (2) external diameter is 0.8 ~ 1.0mm, wall thickness 0.2mm, length 5.0 ~ 8.0mm.
4. magnesium-alloy tube according to claim 1 connects radioactive particle chain, it is characterized in that radioactive particle (1) two ends thread surface pitch 0.1 ~ 0.2mm, hand of spiral is right-handed thread, and the flat shape of screw thread can be triangle, rectangle, trapezoidal or zigzag.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420152981.7U CN204170122U (en) | 2014-03-31 | 2014-03-31 | Magnesium-alloy tube is threaded radioactive particle chain |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420152981.7U CN204170122U (en) | 2014-03-31 | 2014-03-31 | Magnesium-alloy tube is threaded radioactive particle chain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN204170122U true CN204170122U (en) | 2015-02-25 |
Family
ID=52558967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420152981.7U Expired - Lifetime CN204170122U (en) | 2014-03-31 | 2014-03-31 | Magnesium-alloy tube is threaded radioactive particle chain |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN204170122U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109173092A (en) * | 2018-09-25 | 2019-01-11 | 天津赛德医药研究院有限公司 | It is a kind of easily from the Inner irradiation device taken out in vivo |
-
2014
- 2014-03-31 CN CN201420152981.7U patent/CN204170122U/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109173092A (en) * | 2018-09-25 | 2019-01-11 | 天津赛德医药研究院有限公司 | It is a kind of easily from the Inner irradiation device taken out in vivo |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term |
Granted publication date: 20150225 |