CN201768261U - Degradable radioactive seeds source with chemotherapy function - Google Patents

Degradable radioactive seeds source with chemotherapy function Download PDF

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Publication number
CN201768261U
CN201768261U CN2010205195041U CN201020519504U CN201768261U CN 201768261 U CN201768261 U CN 201768261U CN 2010205195041 U CN2010205195041 U CN 2010205195041U CN 201020519504 U CN201020519504 U CN 201020519504U CN 201768261 U CN201768261 U CN 201768261U
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CN
China
Prior art keywords
kernel
degradable
chemotherapy
shell body
carrier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2010205195041U
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Chinese (zh)
Inventor
任天斌
韩宇
宁飞飞
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SHANGHAI TONGBO MATERIAL TECHNOLOGY Co Ltd
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SHANGHAI TONGBO MATERIAL TECHNOLOGY Co Ltd
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Priority to CN2010205195041U priority Critical patent/CN201768261U/en
Application granted granted Critical
Publication of CN201768261U publication Critical patent/CN201768261U/en
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Expired - Fee Related legal-status Critical Current

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  • Biological Depolymerization Polymers (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

The utility model discloses a degradable radioactive seeds source with chemotherapy function comprising an inner core and an outer housing. The inner core is made of the degradable polylactic acid material, and the outer housing is made of the degradable polyurethane material. The inner core and the outer housing can form a sealing cavity, in which is disposed a medical carrier. The utility model adopts a four-edge structure, which has good fastness performance and high sealing degree after being implanted in human body and has the partial chemotherapy function. Because the inner core and the outer housing are made of biodegradable polymer, the same two can be degraded at the same time, when the medical carrier isotope finishes the chemotherapy, then the inner core and the outer housing can be excreted from the body through the metabolism.

Description

Have the degradable radioactive particle source of chemotherapy function concurrently
Technical field
This utility model relates to a kind of degradable radioactive particle source that has the chemotherapy effect concurrently, belongs to biomedical materials field.
Background technology
Radioactive particle is a kind of new tool that is used for treatment of cancer at present, and the accuracy that it has realized local radiotherapy has reduced the damage to normal structure.Radioactive particle claims gamma knife in the body again, and radioactive particle is mainly made with metal material at present.Existing modal radioactive particle is to utilize Electrostatic Absorption on silver-colored rod, and iodine radioisotope 125 is gone up in absorption again, wraps up in titanium to make diameter be 0.8mm in that the silver rod is outer, and length is the metal particle by the emperor himself of 4.5mm.It mainly discharges x and gamma-rays, and ray energy is 27-35kev, and the half-life is 59.6 days, tissue penetration ability 1.7cm.The effective ways that radioactive particle is little because of its good effect side effect, Wicresoft, raising patient become the up-to-date treatment malignant tumor in the present world quality of life all are suitable for early, middle and late phase cancer.Radioactive particle has been widely used in the thousands of examples of kinds of tumors such as thyroid carcinoma, laryngeal carcinoma, the esophageal carcinoma, pulmonary carcinoma, breast carcinoma, hepatocarcinoma, gastric cancer, colorectal cancer.
There is defective-permanent implantation in existing radioactive particle in application, because particle size is very little, and very inconvenient taking-up, the use of existing radioactive particle is irreversible substantially.This means in treatment finishes the back patient body forever to have kept metallic, can increase outside the treatment misery to patient undoubtedly such as each side such as psychology.When the drug level that needs when treatment is very big, will occur a lot of radioactive particles in the patient body, such operation is implanted and can be given the permanent increase of patient many external metallicses.
Therefore, this utility model patent has designed a kind of novel degradable radioactive particle that has the chemotherapy effect concurrently.
Summary of the invention
For solving the problems of the technologies described above, this utility model provides a kind of degradable radioactive particle source that has the chemotherapy function concurrently, by improvement to shape and structural grouping, provide the biodegradable radioactive particle that a kind of fastness is good, tightness is high source, to overcome the existing shortcoming and defect that metallic is forever implanted, side effect is big.
This utility model is to realize by following technical scheme:
A kind of degradable radioactive particle source that has the chemotherapy function concurrently, the shell body that comprises kernel and kernel outside, described kernel is a degradable poly lactate material kernel, described shell body is a degradable polyurethane material shell body, described kernel and shell body form seal chamber, are loaded with medical carrier between seal chamber.
Described medical carrier is the mixed carrier of carrier radioisotope and the medical fluorescent dye of carrier.Be used to carry out radiotherapy.
Described kernel has identical external shape with shell body, is the four rib structures that extend at four angles.Fastness is good behind its implant into body, and tightness is also high.
Described kernel transverse ends is provided with taper kernel staple, further increases the stationarity of implanting, and makes this utility model at its position that need treat performance maximum effect.
The beneficial effects of the utility model are:
1, the biodegradable fallout radioactive material source of this utility model design: kernel and shell body all are to adopt the biodegradable polymer preparation, when carrier radioisotope is finished radiotherapy, kernel and shell body are finished the degraded of particle source simultaneously, and finally excrete by metabolism.
2, the biodegradable fallout radioactive material source of this utility model design: be designed to four rib structures, two ends are provided with the kernel staple, and fastness is good behind its implant into body, tightness is high.
Description of drawings
Fig. 1 is the structure chart that has the degradable radioactive particle source of chemotherapy function concurrently
The specific embodiment
Below in conjunction with accompanying drawing, this utility model is described further.
As Fig. 1, it is the structure chart that has the degradable radioactive particle source of chemotherapy function concurrently, the shell body 2 that comprises kernel 1 and kernel outside, described kernel 1 is a degradable poly lactate material kernel, described shell body 2 is degradable polyurethane material shell bodies, described kernel 1 forms seal chamber with shell body 2, is loaded with medical carrier between seal chamber.
Described medical carrier is the mixed carrier of carrier radioisotope 4 and the medical fluorescent dye 5 of carrier.Be used to carry out radiotherapy.
Described kernel 1 has identical external shape with shell body 2, is the four rib structures that extend at four angles.Fastness is good behind its implant into body, and tightness is also high.
Described kernel 1 transverse ends is provided with taper kernel staple 3, further increases the stationarity of implanting, and makes this utility model maximum in its position that need treat performance
Because this practical new employing is four rib structures, and is provided with the kernel staple at the kernel two ends, fastness is good behind its implant into body, tightness is high, has the local chemotherapy effect concurrently.Kernel and shell body all are to adopt the biodegradable polymer preparation, and when carrier radioisotope was finished radiotherapy, kernel and shell body were finished the degraded of particle source simultaneously, and finally excreted by metabolism.
Size of the present utility model can customize according to the particle source size of specific requirement.

Claims (4)

1. degradable radioactive particle source that has the chemotherapy function concurrently, the shell body that comprises kernel and kernel outside, it is characterized in that described kernel is a degradable poly lactate material kernel, described shell body is a degradable polyurethane material shell body, described kernel and shell body form seal chamber, are loaded with medical carrier between seal chamber.
2. the degradable radioactive particle source that has the chemotherapy function concurrently as claimed in claim 1 is characterized in that described medical carrier is the mixed carrier of carrier radioisotope and the medical fluorescent dye of carrier.
3. the degradable radioactive particle source that has the chemotherapy function concurrently as claimed in claim 1 is characterized in that described kernel and shell body have identical external shape, is the four rib structures that extend at four angles.
4. the degradable radioactive particle source that has the chemotherapy function concurrently as claimed in claim 1 is characterized in that described kernel transverse ends is provided with taper kernel staple.
CN2010205195041U 2010-09-07 2010-09-07 Degradable radioactive seeds source with chemotherapy function Expired - Fee Related CN201768261U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2010205195041U CN201768261U (en) 2010-09-07 2010-09-07 Degradable radioactive seeds source with chemotherapy function

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2010205195041U CN201768261U (en) 2010-09-07 2010-09-07 Degradable radioactive seeds source with chemotherapy function

Publications (1)

Publication Number Publication Date
CN201768261U true CN201768261U (en) 2011-03-23

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Family Applications (1)

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CN2010205195041U Expired - Fee Related CN201768261U (en) 2010-09-07 2010-09-07 Degradable radioactive seeds source with chemotherapy function

Country Status (1)

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CN (1) CN201768261U (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105749300A (en) * 2016-02-24 2016-07-13 赛昂国际医疗技术(中国)有限公司 Marker and transferring device thereof
CN107233662A (en) * 2017-06-23 2017-10-10 宁波君安药业科技有限公司 A kind of radioactive particle chain of use high molecular polymer connecting tube connection

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105749300A (en) * 2016-02-24 2016-07-13 赛昂国际医疗技术(中国)有限公司 Marker and transferring device thereof
CN107233662A (en) * 2017-06-23 2017-10-10 宁波君安药业科技有限公司 A kind of radioactive particle chain of use high molecular polymer connecting tube connection

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C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20110323

Termination date: 20110907