CN109172655A - One kind promote blood circulation essence and its preparation process - Google Patents

One kind promote blood circulation essence and its preparation process Download PDF

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Publication number
CN109172655A
CN109172655A CN201811441482.9A CN201811441482A CN109172655A CN 109172655 A CN109172655 A CN 109172655A CN 201811441482 A CN201811441482 A CN 201811441482A CN 109172655 A CN109172655 A CN 109172655A
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parts
weight
preparation process
root
blood circulation
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黄海平
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Abstract

The invention discloses one kind promote blood circulation essence and its preparation process, belong to technical field of traditional Chinese medicines, one kind is promoted blood circulation essence, divide bulk pharmaceutical chemicals including following parts by weight: root of Chinese clematis 10-60 parts by weight, lopseed 10-60 parts by weight, Radix Notoginseng 5-15 parts by weight, teasel root 3-10 parts by weight, rhizome of davallia 10-60 parts by weight, philippine flemingia root 10-60 parts by weight, the wooden tetrandra root 10-30 parts by weight, lycopodium calvatum 10-60 parts by weight and Caulis et Folium piperis 10-60 parts by weight, its preparation process are as follows: step 1, take root of Chinese clematis 10-60 parts by weight into container, rice vinegar 2-10 parts of stirring is added, bored profit 2-3.5 hours, after rice vinegar liquid is sucked, the root of Chinese clematis is smashed to pieces as the dregs of a decoction, it takes out spare；Step 2: taking lopseed 10-60 parts by weight, lycopodium calvatum 10-60 parts by weight, the 5-7 times of water measured is added to be decocted, it is measured until water surplus is 1-1.5 times, technique preparation promotes blood circulation smart drug absorption degree more preferably, and bioavilability is higher, curative effect is better, preparation time is shorter, is easy to implement multichip carrier continuous medication, greatly improves clinical cure rate.

Description

One kind promote blood circulation essence and its preparation process
Technical field
The present invention relates to technical field of traditional Chinese medicines, promote blood circulation essence and its preparation process more specifically to one kind.
Background technique
Hypertension is the operation inability of blood stasis product with blood lipid height, blood artery sclerosis, internal injury, and blood is unsmooth long to be formed. Qi and blood transporting is incompetent, and myocardium yin-yang is uneven, forms blood supply brain deficiency, becomes myocardial infarction and cerebral thrombosis.Endovascular thrombus It is " the first killer " in crowd's fatal disease.In cardiovascular and cerebrovascular disease, there is a kind of disease for being referred to as " acute arterial embolism ", Once occurring, usually causes limbs or internal organs ischemic necrosis, seriously endanger the health of people.
Thrombus is that the blood at any position in blood circulation system solidifies.Wherein on thrombosis influence it is maximum because Element is the damage of vascular wall, and atherosclerosis is to cause the principal element of vascular damaged.It is attached to heart or big dynamic Thrombus and arteriosclerosis plaque itself on astillen is very unstable in structure, can fall off from tube wall in some cases, shape At embolus, embolus along main artery, middle artery, parteriole direction must blood flow, when front external caliber carefully arrives embolus cannot By when, embolus is just stuck, formed arterial embolism.There is spasm immediately in artery at embolism, keeps external caliber smaller, embolism It is closer.The typical performance of arterial embolism is that burst limbs or brothers refer to toe pain, blackening.It is below horizontal from the arteria renalis The embolus of abdominal aorta, small volume are often gone to generate embolism at foot's parteriole.It is toes severe pain, pale, hair first Cool, stolidity.When embolism position is higher, embolism can be disappeared with lower portion arteriopalmus.It then may occur in which the cyanosis of skin, blueness Spot, foot seems not only dirty but also ugly at this time, shaped like the just soot after rain, therefore title " rubbish foot " barefoot.Thigh or Buttocks parteriole can be had " calf " severe pain by the livedo reticularis that for a long time may occur in which these positions, shank involvement.It can go out after a few days Existing skin, limbs blackening, necrosis.At this moment affected limb oneself can not bring back to life again, have amputation only.Bolt from descending thoracic aorta Son is often fled into the feeding artery of abdominal organs, and the serious change of some internal organs is caused.Such as: embolus enters goldbeater's skin artery and draws Embolism is played, intestinal tube necrosis, perforation, peritonitis can be caused, it is serious to may occur in which infectious shock, threat to life.
At the blood supplies such as Stomach duodenum position abundant, localized plug caused by small embolus can cause to perforate, and lead to reason Unknown massive bleeding from upper digestive tract.If embolus, which is stuck in the arteria renalis, forms embolism, often there is high blood unexpectedly, uncontrollable Pressure, blood urine, kidney failure.Lateral thrombus volume in the chambers of the heart is bigger, flows to lower limb and often forms bolt in common iliac artery, femoral artery etc. Plug easily causes whole leg necrosis.Embolus from heart or aorta ascendens enters upper limb and the chance of brain is relatively more.Embolus into Enter embolism caused by artery of upper extremity performance it is similar with lower limb, the embolus into arteriae cerebri can be formed it has often been said that " in Wind ", i.e. cerebral infarction or cerebral thrombosis.Sometimes the small embolus of heart is turned into coronary artery upon going out heart with blood flow, can draw Play acute myocardial infarction AMI.
The Chinese invention patent that open (bulletin) number is CN1283279C, which discloses, a kind of treats cerebral thrombosis and myocardial infarction Pharmaceutical composition, the composition be pulled out by the root of Chinese clematis, deep, Radix Notoginseng, teasel root, the rhizome of davallia, thousand foldings, Cocculus trilobus, lycopodium calvatum, stone Rise bulk pharmaceutical chemicals composition in south.The invention pharmaceutical composition has the raw new, promoting blood circulation and removing blood stasis of qi and activate blood circulation, continuous blood, have one's ideas straightened out intelligence development the effect of, It is equivalent to treatment headstroke, cerebral hemorrhage, cerebral thrombosis, cerebral embolism, cerebral angiospasm, artery sclerosis and subarachnoid hemorrhage Fruit is significant, which is named as " essence of promoting blood circulation " by inventor.
The invention does not disclose the technique of its preparation, and in the actual use process, the technique of preparation is very simple, with appearance Device fills alcohol, launch in proportion pulled out by the root of Chinese clematis, deep, Radix Notoginseng, teasel root, the rhizome of davallia, thousand foldings, Cocculus trilobus, lycopodium calvatum, heath rise Bulk pharmaceutical chemicals form herbal medicine and impregnate 45 days i.e. finished product, and ratio is 100 kilograms of alcohol, 3 kilograms of medicinal powder, so far, have no other texts It offers open report and the pharmaceutical composition is prepared using Different Preparation.But most drugs are all in the preparation process of the patent Effective component is obtained by the way of alcohol immersion, the time of processing is long, and active constituent content is low, former material in throughput process Material waste is big, so that the stability of drug is low.
Therefore, it is badly in need of providing a kind of new process of pharmaceutical composition for preparing treatment cerebral thrombosis and myocardial infarction, to provide Curative effect is more preferably, stability is good, safe drugs.
Summary of the invention
1. technical problems to be solved
Aiming at the problems existing in the prior art, the purpose of the present invention is to provide one kind promote blood circulation essence and its preparation process, the work Skill preparation promotes blood circulation smart drug absorption degree more preferably, and bioavilability is higher, and curative effect is better, and preparation time is shorter, is easy to implement more Carrier continuous medication greatly improves clinical cure rate.
2. technical solution
To solve the above problems, the present invention adopts the following technical scheme that.
One kind is promoted blood circulation essence, including following parts by weight divide bulk pharmaceutical chemicals:
Root of Chinese clematis 10-60 parts by weight lopseed 10-60 parts by weight Radix Notoginseng 5-15 parts by weight
Teasel root 3-10 parts by weight rhizome of davallia 10-60 parts by weight philippine flemingia root 10-60 parts by weight
The wooden tetrandra root 10-30 parts by weight lycopodium calvatum 10-60 parts by weight Caulis et Folium piperis 10-60 parts by weight
Its preparation process are as follows:
Step 1: taking root of Chinese clematis 10-60 parts by weight into container, rice vinegar 2-10 parts of stirring, bored profit 2-3.5 hours, to rice is added After vinegar liquid body is sucked, the root of Chinese clematis is smashed to pieces as the dregs of a decoction, is taken out spare；
Step 2: taking lopseed 10-60 parts by weight, lycopodium calvatum 10-60 parts by weight are added the 5-7 times of water measured and are decocted, until Water surplus is 1-1.5 times and measures, and lopseed and lycopodium calvatum are smashed to pieces, collects filtrate and filter residue is spare；
Step 3: taking philippine flemingia root 10-60 parts by weight, 5-7 times of addition is measured the ethyl alcohol that volume fraction is 30-50% and is decocted, until Residual liquid quantity is 1-1.5 times and measures, and philippine flemingia root is smashed to pieces, collects filtrate and filter residue is spare；
Step 4: taking Radix Notoginseng 5-15 parts by weight to crush using micronizer is fine powder, collect spare；
Step 5: taking teasel root 3-10 parts by weight, rhizome of davallia 10-60 parts by weight, the wooden tetrandra root 10-30 parts by weight and Caulis et Folium piperis 10-60 Parts by weight of crushed is coarse powder, and the fine powder in step 4 is added, and uses the ethyl alcohol that volume fraction is 60-90% as solvent, carries out close Heated at constant temperature is sealed, controlled at 50-60 degrees Celsius, the duration is 36-48 hours, collects filtrate and filter residue is spare；
Step 6: by above-mentioned steps one, Step 2: the obtained dregs of a decoction and filter residue add 5-7 times to measure in step 3 and step 4 Water decocts 1.5-3 hours, is filtered, resulting filtrate with Step 2: obtained filtrate merges in step 3 and step 4, It is 1.1-1.5 that relative density is concentrated under reduced pressure at 70 DEG C, is dried to get pharmaceutical preparations are arrived.
Further, the preparation process further includes that appropriate amount of auxiliary materials is added to obtained pharmaceutical preparations, is made various doses Type.
Further, the preparation process further includes that suitable refined honey, concentration system is added to obtained pharmaceutical preparations At pill.
Further, the preparation process further includes grinding obtained pharmaceutical preparations, is mixed, packaging is made scattered Agent.
Further, the preparation process further includes that appropriate amount of starch and stearic acid is added to obtained pharmaceutical preparations Magnesium adds appropriate 70% ethyl alcohol and particle is made, dry, and whole grain is encapsulated that capsule is made.
Further, the dosage form is granule, tablet, pill, powder and capsule.
Further, the preparation process further includes that appropriate vegetable oil and beeswax, system are added to obtained pharmaceutical preparations At various externally used pastes.
Further, the preparation process further includes that appropriate moxa is added to obtained pharmaceutical preparations, and various moxibustions are made Agent.
3. beneficial effect
Compared with the prior art, the present invention has the advantages that
The preparation of this programme technique promotes blood circulation smart drug compared with comparing patent, and more preferably, bioavilability is higher for trap, and curative effect is more Good, preparation time is shorter, is easy to implement multichip carrier continuous medication, greatly improves clinical cure rate.
Detailed description of the invention
Fig. 1 is experimental data figure one of the invention；
Fig. 2 is experimental data figure two of the invention；
Fig. 3 is thumb pressing and kneading manipulation schematic diagram of the invention；
Fig. 4 is middle finger pressing and kneading manipulation schematic diagram of the invention.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention；Technical solution in the embodiment of the present invention carries out clear, complete Site preparation description；Obviously；Described embodiments are only a part of the embodiments of the present invention；Instead of all the embodiments, it is based on Embodiment in the present invention；It is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment；It shall fall within the protection scope of the present invention.
In the description of the present invention, it should be noted that the instruction such as term " on ", "lower", "inner", "outside", " top/bottom end " Orientation or positional relationship be based on the orientation or positional relationship shown in the drawings, be merely for convenience of description the present invention and simplification retouch It states, rather than the device or element of indication or suggestion meaning must have a particular orientation, be constructed and operated in a specific orientation, Therefore it is not considered as limiting the invention.In addition, term " first ", " second " are used for description purposes only, and cannot understand For indication or suggestion relative importance.
In the description of the present invention, it should be noted that unless otherwise clearly defined and limited, term " installation " " is set Be equipped with ", " be arranged/connect ", " connection " etc., shall be understood in a broad sense, such as " connection ", may be a fixed connection, be also possible to removable Connection is unloaded, or is integrally connected；It can be mechanical connection, be also possible to be electrically connected；It can be directly connected, it can also be in Between medium be indirectly connected, can be the connection inside two elements.It for the ordinary skill in the art, can be specific Situation understands the concrete meaning of above-mentioned term in the present invention.
Embodiment 1:
One kind is promoted blood circulation essence, including following parts by weight divide bulk pharmaceutical chemicals:
30 parts by weight lopseed of the root of Chinese clematis, 30 parts by weight Radix Notoginseng, 10 parts by weight
The 6 parts by weight rhizome of davallia of teasel root, 30 parts by weight philippine flemingia root, 30 parts by weight
30 parts by weight Caulis et Folium piperis of the wooden 20 parts by weight lycopodium calvatum of tetrandra root, 30 parts by weight
Its preparation process are as follows:
Step 1: taking 30 parts by weight of the root of Chinese clematis into container, 6 parts of rice vinegar stirrings, bored profit 2-3.5 hours, to rice vinegar liquid is added After being sucked, the root of Chinese clematis is smashed to pieces as the dregs of a decoction, is taken out spare；
Step 2: taking 30 parts by weight of lopseed, 30 parts by weight of lycopodium calvatum, the water that 6 times of amounts are added is decocted, until water surplus It is measured for 1.3 times, lopseed and lycopodium calvatum is smashed to pieces, collected filtrate and filter residue is spare；
Step 3: taking 30 parts by weight of philippine flemingia root, the ethyl alcohol that 6 times of amount volume fractions are 40% is added and is decocted, until liquid residual Amount is 1.3 times of amounts, and philippine flemingia root is smashed to pieces, collects filtrate and filter residue is spare；
Step 4: taking 10 parts by weight of Radix Notoginseng to crush using micronizer is fine powder, collect spare；
Step 5: taking 6 parts by weight of teasel root, 30 parts by weight of the rhizome of davallia, wooden 20 parts by weight of tetrandra root and 30 parts by weight of crushed of Caulis et Folium piperis to be The fine powder in step 4 is added in coarse powder, uses the ethyl alcohol that volume fraction is 75% as solvent, is sealed heated at constant temperature, controls Temperature is 55 degrees Celsius, and the duration is 40 hours, collects filtrate and filter residue is spare；
Step 6: by above-mentioned steps one, Step 2: in step 3 and step 4 the obtained dregs of a decoction and filter residue add 6 times amount water Decoct 2 hours, be filtered, resulting filtrate with Step 2: obtained filtrate merges in step 3 and step 4, at 70 DEG C Being concentrated under reduced pressure into relative density is 1.3, is dried to get pharmaceutical preparations are arrived.
Preparation process further includes that appropriate amount of auxiliary materials is added to obtained pharmaceutical preparations, and various dosage forms are made；Preparation process is also Including suitable refined honey is added to obtained pharmaceutical preparations, pill is made in concentration；Preparation process further includes will be obtained Pharmaceutical preparations are ground, and are mixed, and powder is made in packaging；Preparation process further includes being added appropriate to obtained pharmaceutical preparations Starch and magnesium stearate add appropriate 70% ethyl alcohol and particle are made, dry, and whole grain is encapsulated that capsule is made；Dosage form is Granula, tablet, pill, powder and capsule；Preparation process further include be added to obtained pharmaceutical preparations appropriate vegetable oil and Various externally used pastes are made in beeswax；Preparation process further includes that appropriate moxa is added to obtained pharmaceutical preparations, and various moxibustions are made Agent.
Embodiment 2:
One kind is promoted blood circulation essence, including following parts by weight divide bulk pharmaceutical chemicals:
20 parts by weight lopseed of the root of Chinese clematis, 20 parts by weight Radix Notoginseng, 7 parts by weight
The 5 parts by weight rhizome of davallia of teasel root, 30 parts by weight philippine flemingia root, 20 parts by weight
20 parts by weight Caulis et Folium piperis of the wooden 12 parts by weight lycopodium calvatum of tetrandra root, 20 parts by weight
Its preparation process are as follows:
Step 1: taking 20 parts by weight of the root of Chinese clematis into container, 4 parts of rice vinegar stirrings are added, bored profit 2 hours is inhaled to rice vinegar liquid After to the greatest extent, the root of Chinese clematis is smashed to pieces as the dregs of a decoction, is taken out spare；
Step 2: taking 20 parts by weight of lopseed, 20 parts by weight of lycopodium calvatum, the water that 5 times of amounts are added is decocted, until water surplus It is measured for 1.1 times, lopseed and lycopodium calvatum is smashed to pieces, collected filtrate and filter residue is spare；
Step 3: taking 20 parts by weight of philippine flemingia root, the ethyl alcohol that 5 times of amount volume fractions are 35% is added and is decocted, until liquid residual Amount is 1.2 times of amounts, and philippine flemingia root is smashed to pieces, collects filtrate and filter residue is spare；
Step 4: taking 7 parts by weight of Radix Notoginseng to crush using micronizer is fine powder, collect spare；
Step 5: taking 5 parts by weight of teasel root, 30 parts by weight of the rhizome of davallia, wooden 12 parts by weight of tetrandra root and 20 parts by weight of crushed of Caulis et Folium piperis to be The fine powder in step 4 is added in coarse powder, uses the ethyl alcohol that volume fraction is 65% as solvent, is sealed heated at constant temperature, controls Temperature is 55 degrees Celsius, and the duration is 38 hours, collects filtrate and filter residue is spare；
Step 6: by above-mentioned steps one, Step 2: in step 3 and step 4 the obtained dregs of a decoction and filter residue add 5 times amount water Decoct 1.8 hours, be filtered, resulting filtrate with Step 2: obtained filtrate merges in step 3 and step 4,70 DEG C Under to be concentrated under reduced pressure into relative density be 1.2, it is dry to get arriving pharmaceutical preparations.
Preparation process further includes that appropriate amount of auxiliary materials is added to obtained pharmaceutical preparations, and various dosage forms are made；Preparation process is also Including suitable refined honey is added to obtained pharmaceutical preparations, pill is made in concentration；Preparation process further includes will be obtained Pharmaceutical preparations are ground, and are mixed, and powder is made in packaging；Preparation process further includes being added appropriate to obtained pharmaceutical preparations Starch and magnesium stearate add appropriate 70% ethyl alcohol and particle are made, dry, and whole grain is encapsulated that capsule is made；Dosage form is Granula, tablet, pill, powder and capsule；Preparation process further include be added to obtained pharmaceutical preparations appropriate vegetable oil and Various externally used pastes are made in beeswax；Preparation process further includes that appropriate moxa is added to obtained pharmaceutical preparations, and various moxibustions are made Agent.
Embodiment 3:
One kind is promoted blood circulation essence, including following parts by weight divide bulk pharmaceutical chemicals:
50 parts by weight lopseed of the root of Chinese clematis, 50 parts by weight Radix Notoginseng, 40 parts by weight
The 8 parts by weight rhizome of davallia of teasel root, 30 parts by weight philippine flemingia root, 40 parts by weight
55 parts by weight Caulis et Folium piperis of the wooden 28 parts by weight lycopodium calvatum of tetrandra root, 50 parts by weight
Its preparation process are as follows:
Step 1: taking 50 parts by weight of the root of Chinese clematis into container, 9 parts of rice vinegar stirrings, bored profit 3.2 hours, to rice vinegar liquid quilt is added After exhaustion, the root of Chinese clematis is smashed to pieces as the dregs of a decoction, is taken out spare；
Step 2: taking 50 parts by weight of lopseed, 55 parts by weight of lycopodium calvatum, the water that 7 times of amounts are added is decocted, until water surplus It is measured for 1.4 times, lopseed and lycopodium calvatum is smashed to pieces, collected filtrate and filter residue is spare；
Step 3: taking 40 parts by weight of philippine flemingia root, the ethyl alcohol that 7 times of amount volume fractions are 45% is added and is decocted, until liquid residual Amount is 1.4 times of amounts, and philippine flemingia root is smashed to pieces, collects filtrate and filter residue is spare；
Step 4: taking 40 parts by weight of Radix Notoginseng to crush using micronizer is fine powder, collect spare；
Step 5: taking 8 parts by weight of teasel root, 30 parts by weight of the rhizome of davallia, wooden 28 parts by weight of tetrandra root and 50 parts by weight of crushed of Caulis et Folium piperis to be The fine powder in step 4 is added in coarse powder, uses the ethyl alcohol that volume fraction is 80% as solvent, is sealed heated at constant temperature, controls Temperature is 60 degrees Celsius, and the duration is 48 hours, collects filtrate and filter residue is spare；
Step 6: by above-mentioned steps one, Step 2: in step 3 and step 4 the obtained dregs of a decoction and filter residue add 7 times amount water Decoct 2.8 hours, be filtered, resulting filtrate with Step 2: obtained filtrate merges in step 3 and step 4,70 DEG C Under to be concentrated under reduced pressure into relative density be 1.5, it is dry to get arriving pharmaceutical preparations.
Preparation process further includes that appropriate amount of auxiliary materials is added to obtained pharmaceutical preparations, and various dosage forms are made；Preparation process is also Including suitable refined honey is added to obtained pharmaceutical preparations, pill is made in concentration；Preparation process further includes will be obtained Pharmaceutical preparations are ground, and are mixed, and powder is made in packaging；Preparation process further includes being added appropriate to obtained pharmaceutical preparations Starch and magnesium stearate add appropriate 70% ethyl alcohol and particle are made, dry, and whole grain is encapsulated that capsule is made；Dosage form is Granula, tablet, pill, powder and capsule；Preparation process further include be added to obtained pharmaceutical preparations appropriate vegetable oil and Various externally used pastes are made in beeswax；Preparation process further includes that appropriate moxa is added to obtained pharmaceutical preparations, and various moxibustions are made Agent.
In use, can be for oral administration that the ball being prepared into can be used by effect of the oral administration and externally used method to enhance treatment The method of agent, powder, capsule, tablet and granule, external application directly can carry out a wiping using pharmaceutical preparations, put the cave of wiping Position include Baihui, the sun, kan shu, Quze, connected valleys, Huantiao, in committee, Opened Hollow and spring, point wipe after can by thumb pressing and kneading manipulation and Middle finger pressing and kneading manipulation massages corresponding acupuncture point, until drug fully absorbs, carries out a wiping and massage again, repeats 3-5 times, Then the externally used paste made of pharmaceutical preparations is sticked, moxa-preparation made of pharmaceutical preparations is reused, carries out smoked bright acupuncture point, four Under Guan Qi, drug absorption effect is substantially improved, but also curative effect is substantially improved.
Fig. 3-4 is please referred to, thumb pressing and kneading manipulation is exactly to reach certain depth by method in thumb, and patient feels the position attacked a vital point When having sour swollen sense, then slowly rubbing by a small margin is done, 120-160 beats/min of frequency.The characteristics of digital acupoint pressure is not only strong but also soft With points for attention: gimmick strength in application will from light to heavy, surely continue, and must not use swift and violent violence.In addition, It at the end of pressing and kneading manipulation, also not loosen suddenly, to be gradually reduced pressure, middle finger pressing and kneading manipulation is exactly the finger belly of the person's of attacking a vital point middle finger The therapentic part of the patient's body surface is pressed on, wrist loosens, and the ring-swing of active is done by wrist, makes finger belly in body surface therapentic part On do soft, ring by a small margin rotation and rub, 120-160 beats/min of frequency, points for attention: identical with thumb pressing and kneading manipulation.In addition, Index finger is usually taken into the finger back in middle finger when operation, remaining finger flexion is mutually held, and middle finger metacarpophalangeal joints and interphalangeal joint stretch.
" essence of promoting blood circulation " of preparation process preparation anticipates to 89 cerebrovasculars from July, 2016 in September, 2017 through the invention The clinical treatment observation of outer patient, significant in efficacy, verifying situation is as follows:
1, clinical money is trembled
Ordinary circumstance: male 51, female 38；Age is 24 years old minimum, 82 years old maximum.Wherein 45-65 years old at most, share 70 people；
Cerebral arteriovenous malformation 40, hypertension 28, hyperlipemia 12, complicated with diabetes 9；
Clinical manifestation is the case of cerebrovascular accident.Wherein blood pressure is at 160-180/90-110mmHg patient 31；Central 73, wherein left side paralysis 40, right side paralysis 50；Muscular strength 0 degree 12, I degree 3, II degree 11, III degree 14, IV degree 41 Example；Aphasia 12；Dysphagia and the diet hair that drinks water are choked, and are cried by force, are put on an air of cheerfulness 5；Ipsilateral is 8 numb；
Chemical examination detection: the high person of cholesterol: 36, mean value 246mg%, triglyceride raising person 47, mean value 180mg%, Beta lipoprotein raising person 58, mean value 580mg%.
2, observation of curative effect
Curative effect judging standard: muscular strength and sign are unchanged after two months for medication, and blood pressure blood fat is still invalid in ascensionist.It dislikes Change: after one course for the treatment of of medication, not only symptom does not mitigate, and aggravates instead, and there are also bolt tendencys again to occur.Effective: muscular strength increases I Degree, other symptoms progress person, then put wipe a course for the treatment of muscular strength it is still unchanged.Effective: muscular strength increases II degree, and can individually stand walking Person, can take care of oneself life in the case where others assists.Be almost recovered: muscular strength, language, intelligence return to normal, and can take care of oneself life, and can Make housework or working work.
3, treatment results:
Referring to Fig. 1, medication is almost recovered 17 after two months, 19.1% is accounted for；Significant 68,76.4% is accounted for, effective 5, is accounted for 5.6%, deteriorate 0, accounts for 0%.
Referring to Fig. 2, being almost recovered after medication four months 72,80.9% is accounted for；Significant 14, account for 15.7%, effective 3, 3.4% is accounted for, deteriorates 0, accounts for 0%.
Blood Lipid: cholesterol is 193mg% in 8, averagely decline 63mg%；Triglyceride mean value in 26 For 174mg%, averagely decline 44mg%；Mean value is 451 in beta lipoprotein 67, averagely decline 60mg%.
Exploration of Mechanism: net cerebrovascular accident belongs to the scope of Chinese medicine " apoplexy ", and Crack cause has three；One in the blood vessel deficiency of vital energy Blood stasis；Two do not continue in meridian qi and blood；Three in yang blood and qi from keeping.Therefore its interpretation of the cause, onset and process of an illness can be summarized as yin-yang fire tune, qi deficiency to blood stasis；Qi and blood Do not continue, passages through which vital energy circulates is obstructed.Blood new life, drop-over blood vessels should be continued on therapeutic rules with qi and activate blood circulation, eliminating blood stasis and smoothing collaterals, intelligence development of having one's ideas straightened out is adjusted And yin-yang.Strong medicine " essence of promoting blood circulation " acupuncture point point wipes treatment cerebrovascular accident, has the muscular strength that is significantly improved, restores paralyzed limbs Function, and play the role of hypertension and hyperlipemia.Recipe is formed without incompatibility, and it is extremely strong traumatic medicinal that drug, which is deep, is acted on unbiased Contain, dose is also without side-effects greatly, therefore can external application, be conducive to functional rehabilitation.
The medicine of strong medicine " essence of promoting blood circulation ", is different from common Zhitan medicine, the product of not multi-purpose wind-dispelling, only with a small amount of Wheeling Celestial, lycopodium calvatum is main ingredient, this is the feature of we, and transparency replenishing qi and promoting blood flow rises, and matches teasel root blood-activating kidney-tonifying, strengthens the bone and be depressured Lipid-loweringing.Philippine flemingia root is with the logical operation of rhizome of davallia qi and activate blood circulation a surname.The root of Chinese clematis, lycopodium calvatum, which have to search, picks whole body channels and collaterals, and it is raw new suitable to continue blood Blood vessels are connect, the function of traffic new life train of thought makes qi and blood circulation such as ring for no reason.Lopseed carry the root of Chinese clematis, lycopodium calvatum, philippine flemingia root, teasel root, Radix Notoginseng infiltrates through brain even sick institute, and the stasis of blood product of shabby blood helps the blood of new life, promotees qi and blood and reconcile, yin and yang in equilibrium, and four limbs bones of the body collectively is multiple normal. Its transparency, philippine flemingia root, the rhizome of davallia reduce blood pressure obvious lasting.The root of Chinese clematis, lycopodium calvatum, Cocculus trilobus, Radix Notoginseng, teasel root, Piper wallichii (Miq.) Hand.-Mazz. Cholesterol level is effectively reduced.
The preparation of this programme technique promotes blood circulation smart drug compared with comparing patent, and more preferably, bioavilability is higher for trap, treats Effect is more preferable, and preparation time is shorter, is easy to implement multichip carrier continuous medication, greatly improves clinical cure rate.
The foregoing is intended to be a preferred embodiment of the present invention；But scope of protection of the present invention is not limited thereto. Anyone skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its It improves design and is subject to equivalent substitution or change, should be covered by the scope of protection of the present invention.

Claims (8)

  1. The essence 1. one kind is promoted blood circulation, it is characterised in that: divide bulk pharmaceutical chemicals including following parts by weight:
    Root of Chinese clematis 10-60 parts by weight lopseed 10-60 parts by weight Radix Notoginseng 5-15 parts by weight
    Teasel root 3-10 parts by weight rhizome of davallia 10-60 parts by weight philippine flemingia root 10-60 parts by weight
    The wooden tetrandra root 10-30 parts by weight lycopodium calvatum 10-60 parts by weight Caulis et Folium piperis 10-60 parts by weight
    Its preparation process are as follows:
    Step 1: taking root of Chinese clematis 10-60 parts by weight into container, rice vinegar 2-10 parts of stirring, bored profit 2-3.5 hours, to rice is added After vinegar liquid body is sucked, the root of Chinese clematis is smashed to pieces as the dregs of a decoction, is taken out spare；
    Step 2: taking lopseed 10-60 parts by weight, lycopodium calvatum 10-60 parts by weight are added the 5-7 times of water measured and are decocted, until Water surplus is 1-1.5 times and measures, and lopseed and lycopodium calvatum are smashed to pieces, collects filtrate and filter residue is spare；
    Step 3: taking philippine flemingia root 10-60 parts by weight, 5-7 times of addition is measured the ethyl alcohol that volume fraction is 30-50% and is decocted, until Residual liquid quantity is 1-1.5 times and measures, and philippine flemingia root is smashed to pieces, collects filtrate and filter residue is spare；
    Step 4: taking Radix Notoginseng 5-15 parts by weight to crush using micronizer is fine powder, collect spare；
    Step 5: taking teasel root 3-10 parts by weight, rhizome of davallia 10-60 parts by weight, the wooden tetrandra root 10-30 parts by weight and Caulis et Folium piperis 10-60 Parts by weight of crushed is coarse powder, and the fine powder in step 4 is added, and uses the ethyl alcohol that volume fraction is 60-90% as solvent, carries out close Heated at constant temperature is sealed, controlled at 50-60 degrees Celsius, the duration is 36-48 hours, collects filtrate and filter residue is spare；
    Step 6: by above-mentioned steps one, Step 2: the obtained dregs of a decoction and filter residue add 5-7 times to measure in step 3 and step 4 Water decocts 1.5-3 hours, is filtered, resulting filtrate with Step 2: obtained filtrate merges in step 3 and step 4, It is 1.1-1.5 that relative density is concentrated under reduced pressure at 70 DEG C, is dried to get pharmaceutical preparations are arrived.
  2. 2. it is according to claim 1 it is a kind of promote blood circulation essence preparation process, it is characterised in that: the preparation process further include to Appropriate amount of auxiliary materials is added in obtained pharmaceutical preparations, and various dosage forms are made.
  3. 3. it is according to claim 1 it is a kind of promote blood circulation essence preparation process, it is characterised in that: the preparation process further include to Obtained pharmaceutical preparations, are added suitable refined honey, and pill is made in concentration.
  4. 4. it is according to claim 1 it is a kind of promote blood circulation essence preparation process, it is characterised in that: the preparation process further include by Obtained pharmaceutical preparations are ground, and are mixed, and powder is made in packaging.
  5. 5. it is according to claim 1 it is a kind of promote blood circulation essence preparation process, it is characterised in that: the preparation process further include to Obtained pharmaceutical preparations are added appropriate amount of starch and magnesium stearate, add appropriate 70% ethyl alcohol and particle is made, dry, whole Grain, it is encapsulated that capsule is made.
  6. 6. a kind of preparation process of essence of promoting blood circulation according to claim 2, it is characterised in that: the dosage form is granule, piece Agent, pill, powder and capsule.
  7. 7. it is according to claim 1 it is a kind of promote blood circulation essence preparation process, it is characterised in that: the preparation process further include to Appropriate vegetable oil and beeswax is added in obtained pharmaceutical preparations, and various externally used pastes are made.
  8. 8. it is according to claim 1 it is a kind of promote blood circulation essence preparation process, it is characterised in that: the preparation process further include to Appropriate moxa is added in obtained pharmaceutical preparations, and various moxa-preparations are made.
CN201811441482.9A 2018-11-29 2018-11-29 One kind promote blood circulation essence and its preparation process Pending CN109172655A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1579454A (en) * 2003-08-01 2005-02-16 黄升敏 Medicine composition for treating cerebral embolism and myocardial infrarction
CN105833123A (en) * 2016-06-13 2016-08-10 张国显 Chinese medicinal composition for treating venation diseases and preparation method thereof
CN108079115A (en) * 2018-02-24 2018-05-29 王中伟 It is a kind of to treat cirsoid Chinese medicine composition and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1579454A (en) * 2003-08-01 2005-02-16 黄升敏 Medicine composition for treating cerebral embolism and myocardial infrarction
CN105833123A (en) * 2016-06-13 2016-08-10 张国显 Chinese medicinal composition for treating venation diseases and preparation method thereof
CN108079115A (en) * 2018-02-24 2018-05-29 王中伟 It is a kind of to treat cirsoid Chinese medicine composition and preparation method thereof

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Application publication date: 20190111