CN105267889A - Traditional Chinese medicine preparation for treating hyperlipoidemia - Google Patents

Abstract

The invention discloses a traditional Chinese medicine preparation for treating hyperlipoidemia. The traditional Chinese medicine preparation comprises the components of medicated leaven, dutchmanspipe fruit, twotooth achyranthes root, cassia seeds, Hangzhou chrysanthemum flower, earthworms, sweet wormwood herb, leeches, tall gastrodia tuber, notoginseng, turmeric root-tuber, gambir plant, bezoar, safflower, ginkgo leaf, fleece flower root, white silkworms, grass leaf sweelflag rhizome, stem of noble dendrobium, fruit of purpleflower holly, capillary wormwood herb, milkvetch root, tuckahoe, nacre mother of pearl, flower of Japanese pagodatree and borneol. The traditional Chinese medicine preparation for treating hyperlipoidemia, disclosed by the invention, has the effects of clearing away heart fire to cool liver, clearing stasis to remove heat, reducing lipid to activate blood circulation, dissipating blood stasis to calm wind, soothing nerves to open orifices, and inducing diuresis to reduce phlegm, can reduce blood fat, improves organic pathologic changes of important organs of heart, brain, liver, kidney and the like, and can relieve the pain of a patient in a short time. The biggest advantages of the traditional Chinese medicine preparation are that the hyperlipoidemia caused by cardiovascular and cerebrovascular diseases can be fundamentally relieved, the blood fat and the blood viscosity can be reduced, toxic substances in blood and thrombi coagulated on inner walls of blood vessels are effectively eliminated, the resistance of the blood vessels is reduced, the unblocked blood flowing is ensured, arteriosclerosis is prevented, the elasticity of the blood vessels can be enhanced, and the blood vessels can be softened.

Description

A kind of Chinese medicine preparation for the treatment of hyperlipidemia

Technical field

The invention belongs to the field of Chinese medicines, specifically a kind of Chinese medicine preparation can treating hyperlipidemia.

Background technology

Blood fat refers to the general name of various lipid material in blood.Hyperlipidemia refers to lipid metabolism or running is abnormal makes one or more lipids of blood plasma higher than normal value, is a kind of systemic disease, refers to cholesterol in blood and triglyceride is too high or overpopulation protein cholesterol is too low, and modern medicine is referred to as dyslipidemia.

Hyperlipidemia is the commonly encountered diseases of middle-aged and elderly people metabolic disease, frequently-occurring disease, and sickness rate is high, is the principal element causing coronary heart disease, arteriosclerosis, cerebral thrombosis and cerebral hemorrhage.In recent years due to high caloric diet, quantity of motion reduced in addition, and along with the increase at age, sickness rate also progressively increases.Threaten the health of people, cause common concern.

At present, the types of drugs of blood fat reducing is various, is mainly divided into Chinese medicine and the large class of Western medicine two.Western medicine side effect is large, and the lipid lowerers as Statins and Bei Te class all likely causes myositis and brain soldier; Chinese medicine blood fat reducing class types of drugs is many, but ubiquity drug ingredient is mixed, and manufacturing process is numerous and diverse, and lacks supervision, causes quality not ensure.

Summary of the invention

The problem to be solved in the present invention is for above problem, provides the Chinese medicine preparation of the treatment hyperlipidemia that a kind of cure rate is high, therapeutic effect good, have no side effect.

For solving the problem, the technical solution adopted in the present invention is:

Treat a Chinese medicine preparation for hyperlipidemia, it is characterized in that: described Chinese medicine preparation gram to be made up of by weight following raw materials according:

Massa Medicata Fermentata 15-25 gram, Fructus Aristolochiae 10-20 gram, Radix Achyranthis Bidentatae 10-20 gram, Semen Cassiae 15-25 gram, Flos Chrysanthemi 5-10 gram, Pheretima 10-15 gram, Herba Artemisiae Annuae 5-15 gram, Hirudo 0.2-0.8 gram, Rhizoma Gastrodiae 5-15 gram, Radix Notoginseng 5-15 gram, Radix Curcumae 10-20 gram, Ramulus Uncariae Cum Uncis 10-20 gram, Calculus Bovis 5-10 gram, Flos Carthami 5-15 gram, Folium Ginkgo 5-15, Radix Polygoni Multiflori 5-15 gram, Bombyx Batryticatus 5-10 gram, Rhizoma Acori Graminei 5-15 gram, fresh Herba Dendrobii 10-20 gram, Fructus Ilicis Purpureae 10-20 gram, Herba Artemisiae Scopariae 5-15 gram, Radix Astragali 2-8 gram, Poria 5-15 gram, Concha Margaritifera 5-15 gram, Flos Sophorae Immaturus 5-15 gram, Borneolum Syntheticum 5-10 gram.

As a kind of prioritization scheme:

Described Chinese medicine preparation gram to be made up of by weight following raw materials according:

Massa Medicata Fermentata 15 grams, Fructus Aristolochiae 10 grams, Radix Achyranthis Bidentatae 10 grams, Semen Cassiae 15 grams, Flos Chrysanthemi 5 grams, Pheretima 10 grams, Herba Artemisiae Annuae 5 grams, Hirudo 0.2 gram, 5 grams, Rhizoma Gastrodiae, Radix Notoginseng 5 grams, Radix Curcumae 10 grams, Ramulus Uncariae Cum Uncis 10 grams, Calculus Bovis 5 grams, 5 grams, Flos Carthami, Folium Ginkgo 5 grams, the Radix Polygoni Multiflori 5 grams, Bombyx Batryticatus 5 grams, Rhizoma Acori Graminei 5 grams, fresh Herba Dendrobii 10 grams, Fructus Ilicis Purpureae 10 grams, Herba Artemisiae Scopariae 5 grams, the Radix Astragali 2 grams, 5 grams, Poria, Concha Margaritifera 5 grams, the Flos Sophorae Immaturus 5 grams, Borneolum Syntheticum 5 grams.

As a kind of prioritization scheme:

Described Chinese medicine preparation gram to be made up of by weight following raw materials according:

Massa Medicata Fermentata 25 grams, Fructus Aristolochiae 20 grams, Radix Achyranthis Bidentatae 20 grams, Semen Cassiae 25 grams, Flos Chrysanthemi 10 grams, Pheretima 15 grams, Herba Artemisiae Annuae 15 grams, Hirudo 0.8 gram, 15 grams, Rhizoma Gastrodiae, Radix Notoginseng 15 grams, Radix Curcumae 20 grams, Ramulus Uncariae Cum Uncis 20 grams, Calculus Bovis 10 grams, 15 grams, Flos Carthami, Folium Ginkgo 15, the Radix Polygoni Multiflori 15 grams, Bombyx Batryticatus 10 grams, Rhizoma Acori Graminei 15 grams, fresh Herba Dendrobii 20 grams, Fructus Ilicis Purpureae 20 grams, Herba Artemisiae Scopariae 15 grams, the Radix Astragali 8 grams, 15 grams, Poria, Concha Margaritifera 15 grams, the Flos Sophorae Immaturus 15 grams, Borneolum Syntheticum 10 grams.

As a kind of prioritization scheme:

Described Chinese medicine preparation gram to be made up of by weight following raw materials according:

Massa Medicata Fermentata 20 grams, Fructus Aristolochiae 15 grams, Radix Achyranthis Bidentatae 15 grams, Semen Cassiae 20 grams, Flos Chrysanthemi 7 grams, Pheretima 22 grams, Herba Artemisiae Annuae 10 grams, Hirudo 0.5 gram, 10 grams, Rhizoma Gastrodiae, Radix Notoginseng 10 grams, Radix Curcumae 15 grams, Ramulus Uncariae Cum Uncis 15 grams, Calculus Bovis 7 grams, 10 grams, Flos Carthami, Folium Ginkgo 10 grams, the Radix Polygoni Multiflori 10 grams, Bombyx Batryticatus 7 grams, Rhizoma Acori Graminei 10 grams, fresh Herba Dendrobii 15 grams, Fructus Ilicis Purpureae 15 grams, Herba Artemisiae Scopariae 10 grams, the Radix Astragali 5 grams, 10 grams, Poria, Concha Margaritifera 10 grams, the Flos Sophorae Immaturus 10 grams, Borneolum Syntheticum 8 grams.

As a kind of prioritization scheme:

Described Chinese medicine preparation gram to be made up of by weight following raw materials according:

Massa Medicata Fermentata 15 grams, Fructus Aristolochiae 10 grams, Radix Achyranthis Bidentatae 10 grams, Semen Cassiae 15 grams, Flos Chrysanthemi 5 grams, Pheretima 10 grams, Herba Artemisiae Annuae 5 grams, Hirudo 0.2 gram, 5 grams, Rhizoma Gastrodiae, Radix Notoginseng 5 grams, Radix Curcumae 10 grams, Ramulus Uncariae Cum Uncis 10 grams, Calculus Bovis 10 grams, 15 grams, Flos Carthami, Folium Ginkgo 15, the Radix Polygoni Multiflori 15 grams, Bombyx Batryticatus 10 grams, Rhizoma Acori Graminei 15 grams, fresh Herba Dendrobii 20 grams, Fructus Ilicis Purpureae 20 grams, Herba Artemisiae Scopariae 15 grams, the Radix Astragali 8 grams, 15 grams, Poria, Concha Margaritifera 15 grams, the Flos Sophorae Immaturus 15 grams, Borneolum Syntheticum 10 grams.

As a kind of prioritization scheme:

Described Chinese medicine preparation gram to be made up of by weight following raw materials according:

Massa Medicata Fermentata 25 grams, Fructus Aristolochiae 20 grams, Radix Achyranthis Bidentatae 20 grams, Semen Cassiae 25 grams, Flos Chrysanthemi 10 grams, Pheretima 15 grams, Herba Artemisiae Annuae 15 grams, Hirudo 0.8 gram, 15 grams, Rhizoma Gastrodiae, Radix Notoginseng 15 grams, Radix Curcumae 20 grams, Ramulus Uncariae Cum Uncis 20 grams, Calculus Bovis 10 grams, 5 grams, Flos Carthami, Folium Ginkgo 5 grams, the Radix Polygoni Multiflori 5 grams, Bombyx Batryticatus 5 grams, Rhizoma Acori Graminei 5 grams, fresh Herba Dendrobii 10 grams, Fructus Ilicis Purpureae 10 grams, Herba Artemisiae Scopariae 5 grams, the Radix Astragali 2 grams, 5 grams, Poria, Concha Margaritifera 5 grams, the Flos Sophorae Immaturus 5 grams, Borneolum Syntheticum 5 grams.

As a kind of prioritization scheme:

Described Chinese medicine preparation gram to be made up of by weight following raw materials according:

Massa Medicata Fermentata 15 grams, Fructus Aristolochiae 10 grams, Radix Achyranthis Bidentatae 10 grams, Semen Cassiae 15 grams, Flos Chrysanthemi 10 grams, Pheretima 15 grams, Herba Artemisiae Annuae 15 grams, Hirudo 0.8 gram, 5 grams, Rhizoma Gastrodiae, Radix Notoginseng 5 grams, Radix Curcumae 10 grams, Ramulus Uncariae Cum Uncis 10 grams, Calculus Bovis 5 grams, 15 grams, Flos Carthami, Folium Ginkgo 15 grams, the Radix Polygoni Multiflori 15 grams, Bombyx Batryticatus 10 grams, Rhizoma Acori Graminei 5 grams, fresh Herba Dendrobii 10 grams, Fructus Ilicis Purpureae 10 grams, Herba Artemisiae Scopariae 5 grams, the Radix Astragali 2 grams, 15 grams, Poria, Concha Margaritifera 15 grams, the Flos Sophorae Immaturus 15 grams, Borneolum Syntheticum 10 grams.

Wherein:

Massa Medicata Fermentata sweet in the mouth, warm in nature, return spleen, stomach warp, have reduce phlegm, heat clearing away, invigorate blood circulation, blood fat reducing, the effect such as diuretic.

Fructus Aristolochiae bitter in the mouth, cold in nature, return lung, large intestine channel, there is lung heat clearing, sending down the abnormal ascending QI, cough-relieving, relieving asthma, bowel relieving, the hemorrhoid that disappear, reduce phlegm, dissipating blood stasis, the effect such as clear away heart-fire.Fructus Aristolochiae has gentleness and lasting hypotensive effect, is applicable to more early stage hypertension.

Radix Achyranthis Bidentatae sour in the mouth, property is put down, and returns liver, kidney channel, have relieve dizziness, high fever, infantile convulsions, epilepsy, etc., blood stasis dispelling, invigorate blood circulation, stimulate the menstrual flow, ignite that (blood) is descending, diuresis, treating stranguria, reduce phlegm, the effect such as heat clearing away.

Semen Cassiae sweet in the mouth, cold nature, returns liver, large intestine channel, there is heat clearing away, liver heat removing, blood fat reducing, invigorate blood circulation, calm the nerves, diuretic, relieving constipation, the effect such as to reduce phlegm.Semen Cassiae decoct or Trial On The Action of Semen Cassiae Powder can reduce blood plasma ornitrol, triglyceride to Experimental Hyperlipemia disease, and reduce the content of triglyceride in liver.

Flos Chrysanthemi bitter in the mouth, cold nature, returns lung, Liver Channel, the effect such as have dispelling wind, heat radiation, suppressing the hyperactive liver, improving eyesight, heat clearing away, removing toxic substances, cool liver, blood stasis dispelling, blood fat reducing, invigorate blood circulation.

Pheretima salty in the mouth, cold in nature, return liver, lung meridian, there is heat clearing away, suppressing the hyperactive liver, Zhichuan, reduce phlegm, invigorate blood circulation, diuretic, relieve dizziness, high fever, infantile convulsions, epilepsy, etc., the effect such as dredging collateral.Cure mainly high fanatical hot-tempered, convulsion with spasms, headache conjunctival congestion, the diseases such as expectorant heat, apoplexy, hemiplegia of panting.Pheretima extracting solution has good anticoagulation in vitro, can make the clotting time of blood, the equal significant prolongation of thrombin time, prothrombin time, and in pronounced amount effect relationship; Can blood viscosity be reduced, inhibition thrombosis. its anticoagulant mechanism is that it has direct inhibitory action to thrombin-fibrinogen reaction.Pheretima still has fibrinolysis activity, can make established thromboembolism.

Herba Artemisiae Annuae bitter in the mouth, cold in nature, return liver, gallbladder, kidney channel, there is heat clearing away, invigorate blood circulation, cool liver, clear away heart-fire, reduce phlegm, have one's ideas straightened out, dissipating blood stasis, the effect such as relieve dizziness, high fever, infantile convulsions, epilepsy, etc.Arteannuin can decreased heart rate, suppresses myocardial contraction, reduces coronary flow.Intravenous injection has hypotensive activity, but does not affect the booster reaction of norepinephrine, thinks that main system changed the direct suppression of heart.Intravenous injection arteannuin can arrhythmia.

Hirudo bitter in the mouth, cold nature, returns liver, urinary bladder channel, have invigorate blood circulation, dissipating blood stasis, reduce phlegm, heat clearing away, the effect such as relieve dizziness, high fever, infantile convulsions, epilepsy, etc.Containing hirudin and protein in Hirudo body, have that anticoagulant is solid, effect of removing blood stasis with potent drugs blood, cure mainly blood and to fully recover from an illness the diseases such as disease, angiopathy, blood stasis be obstructed.

Rhizoma Gastrodiae sweet in the mouth, property is put down, return Liver Channel, there is suppressing the hyperactive liver, relieve dizziness, high fever, infantile convulsions, epilepsy, etc., invigorate blood circulation, dredging collateral, diuretic, reduce phlegm, dissipating blood stasis, the effect such as heat clearing away.Rhizoma Gastrodiae has dilating effect to a certain degree to coronary artery, peripheral blood vessel, and Gastrodia Injection can make blood pressure drops, decreased heart rate, cardiac output increases, myocardial oxygen consumption declines, and Rhizoma Gastrodiae have promotion myocardial cell energy metabolism, particularly under anaerobic conditions obtains the effect of energy.

Radix Notoginseng mildly bitter flavor, warm in nature, return liver, stomach, the heart, lung, large intestine channel, there is blood stasis dispelling, invigorate blood circulation, heat clearing away, cool liver, and lowering fat, reduce phlegm, the effect such as diuretic.Radix Notoginseng energy antiplatelet aggregation, antithrombus formation.Radix Notoginseng anti-thrombosis function link includes antiplatelet aggregation, antithrombase and promotion plasmin solution preocess.Radix Notoginseng has selectivity dilating effect to different parts blood vessel, to tremulous pulse, as weak in thoracic aorta, dilation of the pulmonary artery effect, and to the small artery such as renal artery, Mesenteric artery, portal vein, postcava and venectasia effect strong, and significantly can reduce coronary resistance, increase coronary flow.

Radix Curcumae sweet in the mouth, cool in nature, GUIXIN, lung, Liver Channel, there is circulation of qi promoting, resolving depression, invigorate blood circulation, removing blood stasis with potent drugs, reduce phlegm, heat clearing away, blood fat reducing, cool liver, clear away heart-fire, relieve dizziness, high fever, infantile convulsions, epilepsy, etc., the effect such as diuretic.Radix Curcumae water decoction does not fall causing atherosclerotic serum cholesterol because of cholesterol, anti-relatively high, phospholipid raises comparatively obvious, and beta lipoprotein, triglyceride slightly rise,, but formation and the lipidosis of aorta and coronary endometrium speckle can be alleviated.

Ramulus Uncariae Cum Uncis bitter in the mouth, cold nature, returns liver, heart channel, there is heat clearing away, suppressing the hyperactive liver, relieve dizziness, high fever, infantile convulsions, epilepsy, etc., dissipating blood stasis, diuretic, calm the nerves, have one's ideas straightened out, blood fat reducing, the effect such as to invigorate blood circulation.

Calculus Bovis bitter in the mouth, cool in nature, GUIXIN, Liver Channel, have clear away heart-fire, eliminating phlegm, have one's ideas straightened out, cool liver, endogenous wind stopping, removing toxic substances, the effect such as blood fat reducing.Calculus Bovis has obvious cardiotonic, and heart rate increases simultaneously, but then makes it to shrink to coronary vasodilator.Have report to point out, the heart tonifying composition of Calculus Bovis is water solublity, has heart tonifying effect to the in vitro heart; Containing the material regulating heartbeat exception in Calculus Bovis water soluble ingredient, its main component may be taurine, for myocardial cell, and the minimizing of myocardial movement cell number and the increase of arrhythmia Beating cells number and heart rate when Calculus Bovis significantly can resist high Ca++; Also the abnormal normalization of the heartbeat caused by low Ca++ can be made.The ischemic cardiac dysfunctions such as the heart rate minimizing that Calculus Bovis still can suppress endotoxin caused and ECG ST section rising.Modern study indicates that Calculus Bovis also has certain hypotensive effect.

Flos Carthami acrid in the mouth, warm in nature, GUIXIN, Liver Channel, have invigorate blood circulation, cool liver, dredging collateral, clear away heart-fire, blood fat reducing, diuretic, the effect such as to reduce phlegm.Safflower oil energy norcholesterol contained in Flos Carthami and hyperlipidemia, softening and blood vessel dilating, anti-aging, endocrine regulation.

Folium Ginkgo bitter in the mouth, property is put down, GUIXIN, lung meridian, have invigorate blood circulation, blood stasis dispelling, clear away heart-fire, blood fat reducing, diuretic, the effect such as to reduce phlegm.Be usually used in the symptom such as treatment hypertension, arteriosclerosis, Takayasu arteritis, occlusive vascular, angina pectoris, cardiac muscle stalk, cerebral embolism, coronary heart disease.Cholesterol levels in blood of human body can be reduced, prevent arteriosclerosis.Eliminate the deposition composition in blood vessel wall, improve hemorheological property, promote erythrocyte deformability, reduce blood viscosity, make blood flow unobstructed, can prevention and therapy cerebral hemorrhage and cerebral infarction.

Radix Polygoni Multiflori bitter in the mouth, slightly warm in nature, returns liver, kidney channel, have nourish blood, YIN nourishing, blood stasis dispelling, heat clearing away, detoxify, relieve dizziness, high fever, infantile convulsions, epilepsy, etc., diuretic, invigorate blood circulation, the effect such as blood fat reducing.The Radix Polygoni Multiflori has blood fat reducing and arteriosclerosis: Radix Polygoni Multiflori ethanol extract gavage, high blood can be suppressed to refer to the rising of the total plasma cholesterol of disease, triglyceride, free cholesterol and cholesteryl ester, delay the atherosis formation and development that beats one's brains.Have and think that the lecithin contained in Radix Polygoni Multiflori is relevant with treatment atherosclerosis.Though but there have report to point out to make cholesterol increase to be slower, pathological changes is slightly light, and do not show, its curative effect is unsure.

Bombyx Batryticatus salty in the mouth, property is put down, and returns liver, lung meridian, have relieve dizziness, high fever, infantile convulsions, epilepsy, etc., dissipating blood stasis, reduce phlegm, blood stasis dispelling, the effect such as heat clearing away.

Rhizoma Acori Graminei bitter in the mouth, warm in nature, GUIXIN, stomach warp, there is removing dampness, whet the appetite, have one's ideas straightened out, eliminating phlegm, refreshment, Fructus Alpiniae Oxyphyllae, invigorate blood circulation, relieve dizziness, high fever, infantile convulsions, epilepsy, etc., the effect such as to regulate the flow of vital energy.Rhizoma Acori Graminei volatile oil has under finite concentration makes the effect of coronary vasodilation. and the clinical treatment being usually used in coronary heart disease, pulmonary heart disease etc. and belonging to the stagnant thoracic obstruction person of expectorant foul smell, its mechanism may to increase coronary flow relevant with it.

Fresh Herba Dendrobii sweet in the mouth, cold nature, returns stomach, kidney channel, have invigorate blood circulation, blood stasis dispelling, heat clearing away, diuretic, reduce phlegm, cool liver, blood fat reducing, the effect such as relieve dizziness, high fever, infantile convulsions, epilepsy, etc.Fresh Herba Dendrobii has the condensation of blood circulation promoting and blood stasis dispelling, blood vessel dilating and antiplatelet, and treatment embolic occlusion pulse tube is scorching, cerebral thrombosis, the effects such as arteriosclerotic obliteration.

Fructus Ilicis Purpureae bitter in the mouth, cool in nature, return liver, kidney channel, there is tonifying liver, kidney tonifying, heat clearing away, reduce phlegm, the effect such as blood stasis dispelling, diuretic.

Herba Artemisiae Scopariae bitter in the mouth, cold nature, returns liver, gallbladder, spleen, stomach warp, there is cool liver, hepatoprotective, invigorate blood circulation, blood fat reducing, diuretic, reduce phlegm, blood stasis dispelling, the effect such as heat clearing away.To experimental hypercholesterolemicrabbits gavage Herba Artemisiae Scopariae decoct, after medication 2-3 week, serum cholesterol obviously declines, and beta lipoprotein also obviously declines, and Cholesterol concentration in aortic tissue content also more obviously reduces, and shows that Herba Artemisiae Scopariae has certain study of anti-atherogenic effect.

Radix Astragali sweet in the mouth, warm in nature, return lung, spleen, liver, kidney channel, there is effects such as having benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, holder skin ulcer granulation promoting, inducing diuresis to remove edema.

Poria sweet in the mouth, property is put down, GUIXIN, lung, spleen, kidney channel, there is diuretic, reduce phlegm, mind calming, calm the nerves, invigorate blood circulation, clear away heart-fire, dissipating blood stasis, relieve dizziness, high fever, infantile convulsions, epilepsy, etc., the effect such as heat clearing away.

Concha Margaritifera salty in the mouth, cold in nature, return liver, heart channel, there is suppressing the hyperactive liver, YANG hyperactivity suppressing, arresting convulsion, stop blooding, reduce phlegm, diuretic, clear away heart-fire, the effect such as to calm the nerves.

Flos Sophorae Immaturus bitter in the mouth, cold nature, returns liver, large intestine channel, there is liver heat removing, reduce phlegm, diuretic, heat clearing away, relieve dizziness, high fever, infantile convulsions, epilepsy, etc., dissipating blood stasis, the effect such as to invigorate blood circulation.

Borneolum Syntheticum bitter in the mouth, cool in nature, GUIXIN, lung meridian, have have one's ideas straightened out, calm the nerves, dissipating blood stasis, heat clearing away, diuretic, reduce phlegm, the effect such as to invigorate blood circulation.

The Chinese medicine preparation that the present invention treats hyperlipidemia is the upper formula adopting multiple medicines science based on theory of Chinese medical science, comprehensive measure makes the effective ingredient of medicine enter blood circulation rapidly, there is the cool liver that clears away heart-fire, dissipating blood stasis and clearing away heat, blood fat reducing invigorated blood circulation, dissipating blood stasis relieves dizziness, high fever, infantile convulsions, epilepsy, etc., calm the nerves have one's ideas straightened out, effect that diuretic reduces phlegm, blood fat can be reduced, improve the organic disease of the vitals such as the heart, brain, liver, kidney, patient can be made to remove slight illness in a short time.Maximum advantage is exactly fundamentally to alleviate the hyperlipidemia that cardiovascular and cerebrovascular disease causes, blood fat and blood viscosity can be reduced, the thrombosis of the noxious substance in effective removing blood and blood vessel condensation, reduce vascular resistance, guarantee unblocked blood flowing, stop arteriosclerosis, the elasticity of blood vessel can be strengthened, vessel softening, avoids the symptom that myocardial infarction or blood supply insufficiency occur.

Manufacture method of the present invention:

By above-mentioned Chinese medicine except after Borneolum Syntheticum mixes by weight, add decocting to hour, filtering medicinal residues, put Borneolum Syntheticum into the liquid, obtain oral liquid.Be ground into end after above-mentioned Chinese medicine can mix by tablet, powder, pill or capsule by weight as made, make tablet, powder, pill or capsule.

Instructions of taking: every day potion, once a day, early bfore meals, within ten days, be a course for the treatment of.

For investigating clinical efficacy and the safety of medicine of the present invention further, we have selected the treatment curative effect of 100 routine hyperlipemic patients to medicine of the present invention and carry out clinical trial.

Case scenario:

The hyperlipidemic conditions person of liver, kidney, endocrine disorder and drug-induced is eliminated in all cases.100 routine hyperlipidemia cases are divided into two groups at random, wherein, often organize 50 routine hyperlipemic patients.In matched group, male 35 example, women 15 example; 45 years old mean age, the course of disease 3 months to 3 years; In treatment group, male 30 example, women 20 example; 45 years old mean age, the course of disease 6 months to 6 years.

Two groups of cases through statistical analysis, have comparability in sex, age, the course of disease etc.

Matched group adopts appropriate exercise, rational diet, and oral JIANGZHINING KELI 10g, every day three times; Rear oral administration solution decocted by the oral medicine of the present invention for the treatment of group, potion on the one, once-a-day.

Diagnostic criteria:

With reference to Ministry of Public Health, the diagnostic criteria that in State Administration of Traditional Chinese Medicine, some cooperative groups are formulated: T-CHOL TC >=5.70mmol/L; Triglyceride TG >=1.70mmol/L; HDL-C HDL-C, male≤1.03mmol/L, women >=1.16mmol/L; Low-density lipoprotein cholesterol LDL-C >=5.70mmol/L.More than one person and diagnosable is met in first three items.

Observational technique:

Observe: blood fat, hemorheology, blood pressure, heart rate, electrocardio, three large conventional, liver functions.

Criterion of therapeutical effect:

Cure: reach more than 1 person, i.e. TC decline >=60%, TG decline >=70%, HDL-C rising >=0.6mmol/L;

Effective: to reach 1 person, i.e. TC decline >=20%, TG decline >=40%, HDL-C rising >=0.26mmol/L;

Effective: to reach 1 person, i.e. TC decline >=10% ~ 20%, TG decline >=20% ~ 40%, HDL-C rising >=0.10 ~ 0.26mmol/L;

Invalid: to check and do not reach efficiency index person.

Blood lipid level before and after two groups of treatments compares: as shown in Table 1

Table one

Curative effect comparision result after two groups of case treatments is as table two.

Table two

By above-mentioned contrast, can find out that Chinese medicine preparation therapeutic effect of the present invention is remarkable, and take compared with Western medicine, take stopgap measures and effect a permanent cure, cure rate is high, and side effect is little, and relapse rate is low.

Detailed description of the invention

Embodiment 1: a kind of Chinese medicine preparation for the treatment of hyperlipidemia, this medicine is made up of by weight following raw materials according:

Massa Medicata Fermentata 15 grams, Fructus Aristolochiae 10 grams, Radix Achyranthis Bidentatae 10 grams, Semen Cassiae 15 grams, Flos Chrysanthemi 5 grams, Pheretima 10 grams, Herba Artemisiae Annuae 5 grams, Hirudo 0.2 gram, 5 grams, Rhizoma Gastrodiae, Radix Notoginseng 5 grams, Radix Curcumae 10 grams, Ramulus Uncariae Cum Uncis 10 grams, Calculus Bovis 5 grams, 5 grams, Flos Carthami, Folium Ginkgo 5 grams, the Radix Polygoni Multiflori 5 grams, Bombyx Batryticatus 5 grams, Rhizoma Acori Graminei 5 grams, fresh Herba Dendrobii 10 grams, Fructus Ilicis Purpureae 10 grams, Herba Artemisiae Scopariae 5 grams, the Radix Astragali 2 grams, 5 grams, Poria, Concha Margaritifera 5 grams, the Flos Sophorae Immaturus 5 grams, Borneolum Syntheticum 5 grams.

After being mixed by weight by above-mentioned Chinese medicine removing Borneolum Syntheticum, add decocting to hour, filtering medicinal residues, put Borneolum Syntheticum into the liquid, obtain oral liquid.Every day, potion, once a day, early bfore meals, within ten days, is a course for the treatment of.

Embodiment 2: a kind of Chinese medicine preparation for the treatment of hyperlipidemia, this medicine is made up of by weight following raw materials according:

Massa Medicata Fermentata 25 grams, Fructus Aristolochiae 20 grams, Radix Achyranthis Bidentatae 20 grams, Semen Cassiae 25 grams, Flos Chrysanthemi 10 grams, Pheretima 15 grams, Herba Artemisiae Annuae 15 grams, Hirudo 0.8 gram, 15 grams, Rhizoma Gastrodiae, Radix Notoginseng 15 grams, Radix Curcumae 20 grams, Ramulus Uncariae Cum Uncis 20 grams, Calculus Bovis 10 grams, 15 grams, Flos Carthami, Folium Ginkgo 15, the Radix Polygoni Multiflori 15 grams, Bombyx Batryticatus 10 grams, Rhizoma Acori Graminei 15 grams, fresh Herba Dendrobii 20 grams, Fructus Ilicis Purpureae 20 grams, Herba Artemisiae Scopariae 15 grams, the Radix Astragali 8 grams, 15 grams, Poria, Concha Margaritifera 15 grams, the Flos Sophorae Immaturus 15 grams, Borneolum Syntheticum 10 grams.

After being mixed by weight by above-mentioned Chinese medicine removing Borneolum Syntheticum, add decocting to hour, filtering medicinal residues, put Borneolum Syntheticum into the liquid, obtain oral liquid.Every day, potion, once a day, early bfore meals, within ten days, is a course for the treatment of.

Embodiment 3: a kind of Chinese medicine preparation for the treatment of hyperlipidemia, this medicine is made up of by weight following raw materials according:

Massa Medicata Fermentata 20 grams, Fructus Aristolochiae 15 grams, Radix Achyranthis Bidentatae 15 grams, Semen Cassiae 20 grams, Flos Chrysanthemi 7 grams, Pheretima 22 grams, Herba Artemisiae Annuae 10 grams, Hirudo 0.5 gram, 10 grams, Rhizoma Gastrodiae, Radix Notoginseng 10 grams, Radix Curcumae 15 grams, Ramulus Uncariae Cum Uncis 15 grams, Calculus Bovis 7 grams, 10 grams, Flos Carthami, Folium Ginkgo 10 grams, the Radix Polygoni Multiflori 10 grams, Bombyx Batryticatus 7 grams, Rhizoma Acori Graminei 10 grams, fresh Herba Dendrobii 15 grams, Fructus Ilicis Purpureae 15 grams, Herba Artemisiae Scopariae 10 grams, the Radix Astragali 5 grams, 10 grams, Poria, Concha Margaritifera 10 grams, the Flos Sophorae Immaturus 10 grams, Borneolum Syntheticum 8 grams.

Removed above-mentioned Chinese medicine after Borneolum Syntheticum mixes by weight, add decocting to hour, filtering medicinal residues, put Borneolum Syntheticum into the liquid, obtain oral liquid.Every day, potion, once a day, early bfore meals, within ten days, is a course for the treatment of.

Embodiment 4: a kind of Chinese medicine preparation for the treatment of hyperlipidemia, this medicine is made up of by weight following raw materials according:

Massa Medicata Fermentata 15 grams, Fructus Aristolochiae 10 grams, Radix Achyranthis Bidentatae 10 grams, Semen Cassiae 15 grams, Flos Chrysanthemi 5 grams, Pheretima 10 grams, Herba Artemisiae Annuae 5 grams, Hirudo 0.2 gram, 5 grams, Rhizoma Gastrodiae, Radix Notoginseng 5 grams, Radix Curcumae 10 grams, Ramulus Uncariae Cum Uncis 10 grams, Calculus Bovis 10 grams, 15 grams, Flos Carthami, Folium Ginkgo 15, the Radix Polygoni Multiflori 15 grams, Bombyx Batryticatus 10 grams, Rhizoma Acori Graminei 15 grams, fresh Herba Dendrobii 20 grams, Fructus Ilicis Purpureae 20 grams, Herba Artemisiae Scopariae 15 grams, the Radix Astragali 8 grams, 15 grams, Poria, Concha Margaritifera 15 grams, the Flos Sophorae Immaturus 15 grams, Borneolum Syntheticum 10 grams.

After being mixed by weight by above-mentioned Chinese medicine removing Borneolum Syntheticum, add decocting to hour, filtering medicinal residues, put Borneolum Syntheticum into the liquid, obtain oral liquid.Every day, potion, once a day, early bfore meals, within ten days, is a course for the treatment of.

Embodiment 5: a kind of Chinese medicine preparation for the treatment of hyperlipidemia, this medicine is made up of by weight following raw materials according:

Massa Medicata Fermentata 25 grams, Fructus Aristolochiae 20 grams, Radix Achyranthis Bidentatae 20 grams, Semen Cassiae 25 grams, Flos Chrysanthemi 10 grams, Pheretima 15 grams, Herba Artemisiae Annuae 15 grams, Hirudo 0.8 gram, 15 grams, Rhizoma Gastrodiae, Radix Notoginseng 15 grams, Radix Curcumae 20 grams, Ramulus Uncariae Cum Uncis 20 grams, Calculus Bovis 10 grams, 5 grams, Flos Carthami, Folium Ginkgo 5 grams, the Radix Polygoni Multiflori 5 grams, Bombyx Batryticatus 5 grams, Rhizoma Acori Graminei 5 grams, fresh Herba Dendrobii 10 grams, Fructus Ilicis Purpureae 10 grams, Herba Artemisiae Scopariae 5 grams, the Radix Astragali 2 grams, 5 grams, Poria, Concha Margaritifera 5 grams, the Flos Sophorae Immaturus 5 grams, Borneolum Syntheticum 5 grams.

After being mixed by weight by above-mentioned Chinese medicine removing Borneolum Syntheticum, add decocting to hour, filtering medicinal residues, put Borneolum Syntheticum into the liquid, obtain oral liquid.Every day, potion, once a day, early bfore meals, within ten days, is a course for the treatment of.

Embodiment 6: a kind of Chinese medicine preparation for the treatment of hyperlipidemia, this medicine is made up of by weight following raw materials according:

Massa Medicata Fermentata 15 grams, Fructus Aristolochiae 10 grams, Radix Achyranthis Bidentatae 10 grams, Semen Cassiae 15 grams, Flos Chrysanthemi 10 grams, Pheretima 15 grams, Herba Artemisiae Annuae 15 grams, Hirudo 0.8 gram, 5 grams, Rhizoma Gastrodiae, Radix Notoginseng 5 grams, Radix Curcumae 10 grams, Ramulus Uncariae Cum Uncis 10 grams, Calculus Bovis 5 grams, 15 grams, Flos Carthami, Folium Ginkgo 15 grams, the Radix Polygoni Multiflori 15 grams, Bombyx Batryticatus 10 grams, Rhizoma Acori Graminei 5 grams, fresh Herba Dendrobii 10 grams, Fructus Ilicis Purpureae 10 grams, Herba Artemisiae Scopariae 5 grams, the Radix Astragali 2 grams, 15 grams, Poria, Concha Margaritifera 15 grams, the Flos Sophorae Immaturus 15 grams, Borneolum Syntheticum 10 grams.

After being mixed by weight by above-mentioned Chinese medicine removing Borneolum Syntheticum, add decocting to hour, filtering medicinal residues, put Borneolum Syntheticum into the liquid, obtain oral liquid.Every day, potion, once a day, early bfore meals, within ten days, is a course for the treatment of.

Some patients healing case is as follows:

Wu XX, female, 46 years old, suffers from hypertension, hyperlipidemia, hyperglycemia, repeatedly goes hospitalize blood pressure, blood fat, blood glucose still to remain high, and after taking Chinese medicine preparation two weeks of the present invention, blood pressure is steady, and rate and blood-lipid decreased, continues to take and cure after two months.

Yellow XX, man, 40 years old, hyperlipidemia for many years, caused unstable blood pressure, took this medicine after 1 month, and blood fat recovers normal.

Claims (7)

1. treat a Chinese medicine preparation for hyperlipidemia, it is characterized in that: described Chinese medicine preparation gram to be made up of by weight following raw materials according:

Massa Medicata Fermentata 15-25 gram, Fructus Aristolochiae 10-20 gram, Radix Achyranthis Bidentatae 10-20 gram, Semen Cassiae 15-25 gram, Flos Chrysanthemi 5-10 gram, Pheretima 10-15 gram, Herba Artemisiae Annuae 5-15 gram, Hirudo 0.2-0.8 gram, Rhizoma Gastrodiae 5-15 gram, Radix Notoginseng 5-15 gram, Radix Curcumae 10-20 gram, Ramulus Uncariae Cum Uncis 10-20 gram, Calculus Bovis 5-10 gram, Flos Carthami 5-15 gram, Folium Ginkgo 5-15, Radix Polygoni Multiflori 5-15 gram, Bombyx Batryticatus 5-10 gram, Rhizoma Acori Graminei 5-15 gram, fresh Herba Dendrobii 10-20 gram, Fructus Ilicis Purpureae 10-20 gram, Herba Artemisiae Scopariae 5-15 gram, Radix Astragali 2-8 gram, Poria 5-15 gram, Concha Margaritifera 5-15 gram, Flos Sophorae Immaturus 5-15 gram, Borneolum Syntheticum 5-10 gram.

2. Chinese medicine preparation according to claim 1, is characterized in that: described Chinese medicine preparation gram to be made up of by weight following raw materials according:

Massa Medicata Fermentata 15 grams, Fructus Aristolochiae 10 grams, Radix Achyranthis Bidentatae 10 grams, Semen Cassiae 15 grams, Flos Chrysanthemi 5 grams, Pheretima 10 grams, Herba Artemisiae Annuae 5 grams, Hirudo 0.2 gram, 5 grams, Rhizoma Gastrodiae, Radix Notoginseng 5 grams, Radix Curcumae 10 grams, Ramulus Uncariae Cum Uncis 10 grams, Calculus Bovis 5 grams, 5 grams, Flos Carthami, Folium Ginkgo 5 grams, the Radix Polygoni Multiflori 5 grams, Bombyx Batryticatus 5 grams, Rhizoma Acori Graminei 5 grams, fresh Herba Dendrobii 10 grams, Fructus Ilicis Purpureae 10 grams, Herba Artemisiae Scopariae 5 grams, the Radix Astragali 2 grams, 5 grams, Poria, Concha Margaritifera 5 grams, the Flos Sophorae Immaturus 5 grams, Borneolum Syntheticum 5 grams.

3. Chinese medicine preparation according to claim 1, is characterized in that: described Chinese medicine preparation gram to be made up of by weight following raw materials according:

Massa Medicata Fermentata 25 grams, Fructus Aristolochiae 20 grams, Radix Achyranthis Bidentatae 20 grams, Semen Cassiae 25 grams, Flos Chrysanthemi 10 grams, Pheretima 15 grams, Herba Artemisiae Annuae 15 grams, Hirudo 0.8 gram, 15 grams, Rhizoma Gastrodiae, Radix Notoginseng 15 grams, Radix Curcumae 20 grams, Ramulus Uncariae Cum Uncis 20 grams, Calculus Bovis 10 grams, 15 grams, Flos Carthami, Folium Ginkgo 15, the Radix Polygoni Multiflori 15 grams, Bombyx Batryticatus 10 grams, Rhizoma Acori Graminei 15 grams, fresh Herba Dendrobii 20 grams, Fructus Ilicis Purpureae 20 grams, Herba Artemisiae Scopariae 15 grams, the Radix Astragali 8 grams, 15 grams, Poria, Concha Margaritifera 15 grams, the Flos Sophorae Immaturus 15 grams, Borneolum Syntheticum 10 grams.

4. Chinese medicine preparation according to claim 1, is characterized in that: described Chinese medicine preparation gram to be made up of by weight following raw materials according:

Massa Medicata Fermentata 20 grams, Fructus Aristolochiae 15 grams, Radix Achyranthis Bidentatae 15 grams, Semen Cassiae 20 grams, Flos Chrysanthemi 7 grams, Pheretima 22 grams, Herba Artemisiae Annuae 10 grams, Hirudo 0.5 gram, 10 grams, Rhizoma Gastrodiae, Radix Notoginseng 10 grams, Radix Curcumae 15 grams, Ramulus Uncariae Cum Uncis 15 grams, Calculus Bovis 7 grams, 10 grams, Flos Carthami, Folium Ginkgo 10 grams, the Radix Polygoni Multiflori 10 grams, Bombyx Batryticatus 7 grams, Rhizoma Acori Graminei 10 grams, fresh Herba Dendrobii 15 grams, Fructus Ilicis Purpureae 15 grams, Herba Artemisiae Scopariae 10 grams, the Radix Astragali 5 grams, 10 grams, Poria, Concha Margaritifera 10 grams, the Flos Sophorae Immaturus 10 grams, Borneolum Syntheticum 8 grams.

5. Chinese medicine preparation according to claim 1, is characterized in that: described Chinese medicine preparation gram to be made up of by weight following raw materials according:

Massa Medicata Fermentata 15 grams, Fructus Aristolochiae 10 grams, Radix Achyranthis Bidentatae 10 grams, Semen Cassiae 15 grams, Flos Chrysanthemi 5 grams, Pheretima 10 grams, Herba Artemisiae Annuae 5 grams, Hirudo 0.2 gram, 5 grams, Rhizoma Gastrodiae, Radix Notoginseng 5 grams, Radix Curcumae 10 grams, Ramulus Uncariae Cum Uncis 10 grams, Calculus Bovis 10 grams, 15 grams, Flos Carthami, Folium Ginkgo 15, the Radix Polygoni Multiflori 15 grams, Bombyx Batryticatus 10 grams, Rhizoma Acori Graminei 15 grams, fresh Herba Dendrobii 20 grams, Fructus Ilicis Purpureae 20 grams, Herba Artemisiae Scopariae 15 grams, the Radix Astragali 8 grams, 15 grams, Poria, Concha Margaritifera 15 grams, the Flos Sophorae Immaturus 15 grams, Borneolum Syntheticum 10 grams.

6. Chinese medicine preparation according to claim 1, is characterized in that: described Chinese medicine preparation gram to be made up of by weight following raw materials according:

Massa Medicata Fermentata 25 grams, Fructus Aristolochiae 20 grams, Radix Achyranthis Bidentatae 20 grams, Semen Cassiae 25 grams, Flos Chrysanthemi 10 grams, Pheretima 15 grams, Herba Artemisiae Annuae 15 grams, Hirudo 0.8 gram, 15 grams, Rhizoma Gastrodiae, Radix Notoginseng 15 grams, Radix Curcumae 20 grams, Ramulus Uncariae Cum Uncis 20 grams, Calculus Bovis 10 grams, 5 grams, Flos Carthami, Folium Ginkgo 5 grams, the Radix Polygoni Multiflori 5 grams, Bombyx Batryticatus 5 grams, Rhizoma Acori Graminei 5 grams, fresh Herba Dendrobii 10 grams, Fructus Ilicis Purpureae 10 grams, Herba Artemisiae Scopariae 5 grams, the Radix Astragali 2 grams, 5 grams, Poria, Concha Margaritifera 5 grams, the Flos Sophorae Immaturus 5 grams, Borneolum Syntheticum 5 grams.

7. Chinese medicine preparation according to claim 1, is characterized in that: described Chinese medicine preparation gram to be made up of by weight following raw materials according:

Massa Medicata Fermentata 15 grams, Fructus Aristolochiae 10 grams, Radix Achyranthis Bidentatae 10 grams, Semen Cassiae 15 grams, Flos Chrysanthemi 10 grams, Pheretima 15 grams, Herba Artemisiae Annuae 15 grams, Hirudo 0.8 gram, 5 grams, Rhizoma Gastrodiae, Radix Notoginseng 5 grams, Radix Curcumae 10 grams, Ramulus Uncariae Cum Uncis 10 grams, Calculus Bovis 5 grams, 15 grams, Flos Carthami, Folium Ginkgo 15 grams, the Radix Polygoni Multiflori 15 grams, Bombyx Batryticatus 10 grams, Rhizoma Acori Graminei 5 grams, fresh Herba Dendrobii 10 grams, Fructus Ilicis Purpureae 10 grams, Herba Artemisiae Scopariae 5 grams, the Radix Astragali 2 grams, 15 grams, Poria, Concha Margaritifera 15 grams, the Flos Sophorae Immaturus 15 grams, Borneolum Syntheticum 10 grams.