CN109170173A - A kind of insect metabolin additive and its preparation method and application - Google Patents
A kind of insect metabolin additive and its preparation method and application Download PDFInfo
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- CN109170173A CN109170173A CN201811208106.5A CN201811208106A CN109170173A CN 109170173 A CN109170173 A CN 109170173A CN 201811208106 A CN201811208106 A CN 201811208106A CN 109170173 A CN109170173 A CN 109170173A
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- insect
- metabolin
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- albumen powder
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/20—Animal feeding-stuffs from material of animal origin
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
- A23K20/147—Polymeric derivatives, e.g. peptides or proteins
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- Polymers & Plastics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Animal Husbandry (AREA)
- Biomedical Technology (AREA)
- Physiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Fodder In General (AREA)
Abstract
The present invention discloses a kind of insect metabolin additive and its preparation method and application, using insect metabolin and Flyblow albumen powder as main component, without using traditional carrier and diluent.It can not only safeguard the intestinal health of animal, improve animal immunizing power, a degree of proteinaceous nutrient can also be provided for animal, while saving carrier cost.
Description
Technical field
The present invention relates to field of animal feed, relates generally to a kind of insect metabolin additive and preparation method thereof and answer
With.
Background technique
Feed addictive is to meet animal special dietary and health care needs, improving animal product quality and guaranteeing feeding
Expect product quality and a small amount of or micro substance in feed is added.Feed addictive is the original that modern feed industry necessarily uses
Material improves breeding performonce fo animals to basal feed nutritive value is strengthened, and guarantees animal health, saves feed cost, improves livestock products
Product quality etc. has obvious effects on, and is one of big pillar of modern mixed feed three.
Under the conditions of intensive culture, highdensity feeding environment causes animal immunizing power low, and animal is easier by not
Good external microbe infringement, leads to the generation of various diseases.Therefore the medicines such as antibiotic, pest repellant are used in animal mixed feed
Object additive is one of disease preventing and treating, the conventional means for promoting breeding performonce fo animals.But excessively use medicated premix meeting
The problems such as causing medicament residue, drug resistance generation, antibody-resistant bacterium cross transmission.
Traditional feed addictive will use a large amount of nonnutritive carriers and dilute to adsorb and dilute each active principle
Agent (such as zeolite, system chaff) is released, the feed cost of raiser is virtually improved.
Moreover, traditional medicated feed additive active principle is less, using effect is single, and mostly chemical industry synthesis product,
Animal large dosage intake for a long time has certain side effect.In predictable future, the substances such as antibiotic will be in feed industry
Be forced to disable in animal farming industry, therefore oriented development such as natural, green, organic of medicated feed additive at present become
Gesture.
Therefore, the existing technology needs to be improved and developed.
Summary of the invention
In view of above-mentioned deficiencies of the prior art, the purpose of the present invention is to provide a kind of insect metabolin additive and its systems
Preparation Method and application, using insect metabolin and Flyblow albumen powder as main component, without using traditional carrier and diluent, purport
Solving the problems, such as that existing feed addictive will cause medicament residue, drug resistance generates and carrier is at high cost.
Technical scheme is as follows:
A kind of insect metabolin additive, wherein carrier and diluent are free of, in parts by weight, including following components:
10 ~ 50 parts of insect metabolin；
950 ~ 990 parts of Flyblow albumen powder.
The insect metabolin additive, wherein the Flyblow albumen powder is that the prosperous peptide biotechnology share in Guangdong is limited
The insect protein KT100 of company.
The insect metabolin additive, wherein the insect metabolin is that gained is extracted from fly maggot powder.
The insect metabolin additive, wherein the extracting method of the insect metabolin the following steps are included:
Fly maggot is dried, moisture≤10% is made；
Fly maggot after drying is crossed into 80 meshes, is crushed；
Fly maggot powder metabolin extracting solution is impregnated into 36 ~ 60h, is filtered after immersion；Wherein, the volume ratio of the extracting solution is
Methanol: acetonitrile: acetone: water=20-40:20-40:20-40:10-20；
Gained filter residue impregnates 36 ~ 60h with new metabolin extracting solution again, filters after immersion, merges filtrate twice；
Filtrate is freeze-dried after -60 DEG C of 12 ~ 36h of placement, obtains insect metabolin powder.
A kind of preparation method of insect metabolin additive as described above, wherein the following steps are included:
Flyblow albumen powder was crushed to 40 meshes, drying makes its moisture≤10%；
Weigh insect metabolin and Flyblow albumen powder；
Insect metabolin and Flyblow albumen powder are sent into mixing machine and mixed.
A kind of application of insect metabolin additive as described above, wherein be used for the insect metabolin additive
It is added in animal feed.
The application of the insect metabolin additive, wherein additive amount of the insect metabolin additive in feed be
0.05%。
The utility model has the advantages that insect metabolin additive of the invention, is main former with insect metabolite and Flyblow albumen powder
Material can not only safeguard the intestinal health of animal in this way, improve animal immunizing power, also without using traditional carrier and diluent
A degree of proteinaceous nutrient can be provided for animal, while saving carrier cost.
Specific embodiment
The present invention provides a kind of insect metabolin additive and its preparation method and application, to make the purpose of the present invention, skill
Art scheme and effect are clearer, clear, and the present invention is described in more detail below.It should be appreciated that tool described herein
Body embodiment is only used to explain the present invention, is not intended to limit the present invention.
The present invention provides a kind of insect metabolin additive, is a health care type feedstuff additive product, raw material therein
Mainly insect metabolin and Flyblow albumen powder, without using traditional carrier and diluent, but with Flyblow albumen powder (purchased from wide
Dong Xin peptide biotech inc, insect protein KT100) carry out Adsorption of components, animal can be not only safeguarded in this way
Intestinal health, improve animal immunizing power, a degree of proteinaceous nutrient can also be provided for animal, at the same save carrier at
This.
Specifically, the insect metabolin additive, without containing traditional carrier and diluent, in parts by weight,
Including following components:
10 ~ 50 parts of insect metabolin；
950 ~ 990 parts of Flyblow albumen powder.
The insect metabolin is that gained is extracted from fly maggot powder.The preparation method of the insect metabolin, including it is following
Step:
Fly maggot is dried, it is ensured that moisture≤10%；
Fly maggot after drying is crossed into 80 meshes, is crushed；
Fly maggot powder metabolin extracting solution is impregnated into 36 ~ 60h, is filtered after immersion；
Gained filter residue impregnates 36 ~ 60h with new metabolin extracting solution again, filters after immersion, merges filtrate twice；
Filtrate is freeze-dried after -60 DEG C of 12 ~ 36h of placement, obtains insect metabolin powder.
Wherein, the volume ratio of the extracting solution is methanol: acetonitrile: acetone: water=20-40:20-40:20-40:10-
20.The work that probiotics, the antibacterial peptide etc. in fly maggot powder are beneficial to animal health growth can be obtained as far as possible using this extracting solution
Property constituents extraction comes out.
In insect metabolite, protein content is abundant, and is beneficial to animal health growth containing profitable probliotics, antibacterial peptide etc.
Active constituent.After testing, according to mass percent meter, including following component:
Insect association probiotics 10 ~ 20%；
Insect antimicrobial peptide 10 ~ 18%；
Insect complex enzyme 10 ~ 17%；
Glutathione 0.1 ~ 0.3%；
Glutamine 0.1 ~ 0.5%；
Chitosan 8 ~ 14%；
Nucleotide 4 ~ 8%；
Organic acid 10 ~ 16%；
Free amino acid 5 ~ 9%；
Other peptide protein 20 ~ 30%.
Other peptide albumen include the substances such as macromolecular peptide, small-molecular peptides, food calling peptide.
The insect metabolin has following biological characteristic:
1, there is antibacterial peptide wide spectrum to kill bacteriostatic activity, " insect antibiotic " is known as, to bacterium, mycoplasma, virus, helminth etc.
It is the green bioactive substance of alternative antibiotic with inhibition and lethal effect；
2, probiotics is the lactic acid bacteria of the bacillus category for isolating and purifying out and anti-adversity brilliance from insect metabolism, drop
Solve nutriment ability it is strong, heat-resisting, acidproof, resistance to drying, and resist gastric acid and bile ability it is strong, can rapidly gastrointestinal tract field planting with
Breeding；
3, the digestibility of nutriment in feed can be improved in the substances such as digestive ferment, organic acid, amino acid；
4, the insects metabolite such as glutathione, glutamine, nucleotide, chitosan can significantly increase vivo immunization and adjust function
Can, while impaired enteron aisle can be quickly repaired, to safeguard animal normal stool absorption function.
The preparation method of the insect metabolin additive is also provided in the present invention, comprising the following steps:
Flyblow albumen powder was crushed to 40 meshes, drying makes its moisture≤10%, it is stand-by to be delivered to batch bin；
Start a small amount of weighers according to formula and precise is carried out to insect metabolin and Flyblow albumen powder；
After weighing, insect metabolin and Flyblow albumen powder are sent into mixing machine and mixed；
Uniformly mixed finished product is delivered to finished bin, extremely stores in a warehouse by electronic scale and metering baling press packing packaging.
The insect metabolin additive, protein content >=30%, moisture≤10%；Bacillus subtilis >=1 ×
109Cfu/g, bacillus coagulans >=1 × 109 Cfu/g, bacillus licheniformis >=1 × 109Cfu/g, lactobacillus acidophilus >=1 ×
109cfu/g.The present invention also provides the applications of the insect metabolin additive, and the insect metabolin additive is used to add
It is added in animal feed.It is preferably 0.05% in additive amount of the insect metabolin additive in feed.
Insect metabolin additive provided by the present invention has the advantage that compared with conventional medicament feed addictive
1, conventional medicament feed addictive main component is all antibiotic, synthetic antibiotic, pest repellant, chemical industry synthesis medicine etc., though
Suppression effect so is killed to microorganisms such as bacterium, helminths, but is easy to produce high drug resistance, high residue, height after animal intake
Toxic side effect drains the ill-effects such as slow, seriously affects animal health and food safety.And insect metabolism provided by the present invention
Object additive main active is insect metabolin, is the concentrated extract of insect metabolite, insect antimicrobial peptide therein
It is a kind of main matter of insect humoral immunity, has to the microorganisms such as bacterium, virus, mycoplasma, helminth and tumour cell
Killing and inhibiting effect, are a kind of antibacterial bioactive substances of wide spectrum, " natural antibiotics " are known as, in conjunction in metabolin
Insect association probiotics, Efficient killing effect and inhibition can be caused to the intracorporal harmful microorganism of animal, and due to being natural
The organic biological active substance of synthesis, therefore have no adverse effects to animal health.
2, conventional medicament feed addictive component is single, and effective component is essentially one to two kinds, and using effect is relatively simple
And concentration.And insect metabolin is poly- comprising probiotics, insect antimicrobial peptide, digestive ferment, organic acid, glutamine, glutathione, shell
The bioactive substances such as sugar, nucleotide, peptide albumen, other than antibacterial peptide has broad-spectrum bactericidal action, probiotics can be with balanced dynamic
Object micro ecology of gastrointestinal tract environment, digestive ferment can help animal digestion to absorb nutriment, and organic acid can be with food calling and balancing machine
Animal immunizing power can be improved in body acid-base balance, glutamine, glutathione and nucleotide, and chitosan can repair animal intestinal tract
The effects of damage and precocious promotion young animal enteron aisle, therefore insect metabolin is a kind of natural multiple hydrocarbon generation system collection
Zoarium can play more effects after animal intake.
3, the carrier and diluent that the nonnutritive values such as a large amount of zeolite, system chaff have been used in conventional feed additive come
Adsorption of components, usage amount is up to 70% ~ 80% or more.And carrier and dilution are not used in insect metabolin additive of the invention
Agent directly carrys out Adsorption of components using fly maggot powder, saves this feed a part cost.
Below by way of specific embodiment, the invention will be further described.
Embodiment
Insect metabolin additive, in parts by weight, including following components:
50 parts of insect metabolin；
950 parts of Flyblow albumen powder.
Tested on Guangdong pig farm, select the healthy piggy 120 of 30kg or so, be randomly divided into 2 groups --- control group
And test group, every group of 6 repetitions, each repetition 10.Control group fed is prepared common based on Corn-soybean-fish meal
Small swine rations, test group daily ration then add 0.05% insect metabolin additive, two kinds of diet nutrients on the basis of control group daily ration
It is on close level, test period is 18, and management is managed according to daily pig farm and carried out.
Test result show test group average daily gain 65 grams more than control group/head/day (P < 0.05), improve
9.5%；Whole feedstuff-meat ratio reduces 0.18 compared to the control group；Diarrhea rate is down to 0.7% from 2.1% compared to the control group.Illustrate in piggy
Insect metabolin additive is added in daily ration, the body aggregate velocity of pig is accelerated, and abilities of digestive and absorption is stronger, and gastrointestinal tract is more strong
Health, and piggy overall immunity enhances.
It should be understood that the application of the present invention is not limited to the above for those of ordinary skills can
With improvement or transformation based on the above description, all these modifications and variations all should belong to the guarantor of appended claims of the present invention
Protect range.
Claims (7)
1. a kind of insect metabolin additive, which is characterized in that carrier and diluent are free of, in parts by weight, including with
Lower component:
10 ~ 50 parts of insect metabolin；
950 ~ 990 parts of Flyblow albumen powder.
2. insect metabolin additive according to claim 1, which is characterized in that the Flyblow albumen powder is the prosperous peptide in Guangdong
The insect protein KT100 of biotech inc.
3. insect metabolin additive according to claim 1, which is characterized in that the insect metabolin is from fly maggot powder
Obtained by middle extraction.
4. insect metabolin additive according to claim 3, which is characterized in that the extracting method of the insect metabolin
The following steps are included:
Fly maggot is dried, moisture≤10% is made；
Fly maggot after drying is crossed into 80 meshes, is crushed；
Fly maggot powder metabolin extracting solution is impregnated into 36 ~ 60h, is filtered after immersion；Wherein, the volume ratio of the extracting solution is
Methanol: acetonitrile: acetone: water=20-40:20-40:20-40:10-20；
Gained filter residue impregnates 36 ~ 60h with new metabolin extracting solution again, filters after immersion, merges filtrate twice；
Filtrate is freeze-dried after -60 DEG C of 12 ~ 36h of placement, obtains insect metabolin powder.
5. a kind of preparation method of the insect metabolin additive as described in claim 1-4 is any, which is characterized in that including with
Lower step:
Flyblow albumen powder was crushed to 40 meshes, drying makes its moisture≤10%；
Weigh insect metabolin and Flyblow albumen powder；
Insect metabolin and Flyblow albumen powder are sent into mixing machine and mixed.
6. a kind of application of the insect metabolin additive as described in claim 1-4 is any, which is characterized in that by the insect
Metabolin additive is for being added in animal feed.
7. the application of insect metabolin additive according to claim 6, which is characterized in that insect metabolin additive exists
Additive amount in feed is 0.05%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811208106.5A CN109170173A (en) | 2018-10-17 | 2018-10-17 | A kind of insect metabolin additive and its preparation method and application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811208106.5A CN109170173A (en) | 2018-10-17 | 2018-10-17 | A kind of insect metabolin additive and its preparation method and application |
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| CN109170173A true CN109170173A (en) | 2019-01-11 |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1297692A (en) * | 1999-12-01 | 2001-06-06 | 中国科学院动物研究所 | Animal feed additive and its preparation |
| CN102293785A (en) * | 2011-08-29 | 2011-12-28 | 河南科技大学 | Method for extracting secondary metabolites of insects or arthropods |
| CN102578390A (en) * | 2012-02-17 | 2012-07-18 | 郎影菲 | Insect additive for poultry and livestock feeds and application of insect additive |
| CN102603921A (en) * | 2012-02-17 | 2012-07-25 | 郎影菲 | Comprehensive treatment method and application of insects |
| CN103655627A (en) * | 2012-09-07 | 2014-03-26 | 河南科技大学 | Extraction method and antibacterial activity screening method for fat-soluble active ingredients in insects and arthropods |
| CN105614074A (en) * | 2015-12-25 | 2016-06-01 | 广东鑫肽生物科技股份有限公司 | Novel insect protein concentrated feed with additive amount being 4% |
-
2018
- 2018-10-17 CN CN201811208106.5A patent/CN109170173A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1297692A (en) * | 1999-12-01 | 2001-06-06 | 中国科学院动物研究所 | Animal feed additive and its preparation |
| CN102293785A (en) * | 2011-08-29 | 2011-12-28 | 河南科技大学 | Method for extracting secondary metabolites of insects or arthropods |
| CN102578390A (en) * | 2012-02-17 | 2012-07-18 | 郎影菲 | Insect additive for poultry and livestock feeds and application of insect additive |
| CN102603921A (en) * | 2012-02-17 | 2012-07-25 | 郎影菲 | Comprehensive treatment method and application of insects |
| CN103655627A (en) * | 2012-09-07 | 2014-03-26 | 河南科技大学 | Extraction method and antibacterial activity screening method for fat-soluble active ingredients in insects and arthropods |
| CN105614074A (en) * | 2015-12-25 | 2016-06-01 | 广东鑫肽生物科技股份有限公司 | Novel insect protein concentrated feed with additive amount being 4% |
Non-Patent Citations (3)
| Title |
|---|
| 大海无疆: "昆虫蛋白KT100", 《网页网址：HTTPS://WWW.MEIPIAN.CN/E0F2OND》 * |
| 徐丽兰等: "无菌蝇蛆在饲料领域中的应用及研究进展", 《中国畜牧兽医》 * |
| 王敦等: "昆虫源蛋白质、壳聚糖、脂肪酸在动物营养和饲料中的应用研究与前景", 《西北林学院学报》 * |
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Application publication date: 20190111 |