CN109157744A - A kind of ultrasonic transducer bracket for toy through cranium magnetosonic stimulation precise positioning - Google Patents

A kind of ultrasonic transducer bracket for toy through cranium magnetosonic stimulation precise positioning Download PDF

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Publication number
CN109157744A
CN109157744A CN201811050561.7A CN201811050561A CN109157744A CN 109157744 A CN109157744 A CN 109157744A CN 201811050561 A CN201811050561 A CN 201811050561A CN 109157744 A CN109157744 A CN 109157744A
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CN
China
Prior art keywords
axis support
support arm
energy converter
ultrasonic transducer
stimulation
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CN201811050561.7A
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Chinese (zh)
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CN109157744B (en
Inventor
周晓青
王会琴
殷涛
刘志朋
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Institute of Biomedical Engineering of CAMS and PUMC
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Institute of Biomedical Engineering of CAMS and PUMC
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Priority to CN201811050561.7A priority Critical patent/CN109157744B/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/002Magnetotherapy in combination with another treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/004Magnetotherapy specially adapted for a specific therapy
    • A61N2/006Magnetotherapy specially adapted for a specific therapy for magnetic stimulation of nerve tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/12Magnetotherapy using variable magnetic fields obtained by mechanical movement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N2007/0004Applications of ultrasound therapy
    • A61N2007/0021Neural system treatment
    • A61N2007/0026Stimulation of nerve tissue

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Surgical Instruments (AREA)

Abstract

A kind of ultrasonic transducer bracket for toy through cranium magnetosonic stimulation precise positioning, it include firm banking, the Z axis support component for being able to carry out vertical adjustment is vertically installed on the firm banking, the upper end of the Z axis support arm is horizontally disposed by the connection of the first cruciform fastening for falsework and is able to carry out one end of the X-axis support arm of Level tune, and the other end of the X-axis support arm connects the energy converter fixation kit for fixing ultrasonic transducer by the second cruciform fastening for falsework.A kind of ultrasonic transducer bracket for toy through cranium magnetosonic stimulation precise positioning of the invention, the movement and rotation of transducer mount can be passed through, realize the accurate focusing regulation stimulated through cranium magnetosonic, the control accurate of focal zone intensity and range at stimulation target spot may be implemented, it is easy to operate, it is easy to use.It can be used for the high focusing nerve modulation of precise positioning, the precise positioning stimulation to stimulate through cranium magnetosonic provides a kind of feasible method.

Description

A kind of ultrasonic transducer bracket for toy through cranium magnetosonic stimulation precise positioning
Technical field
The present invention relates to a kind of ultrasonic transducer brackets.It is stimulated precisely for toy through cranium magnetosonic more particularly to one kind The ultrasonic transducer bracket of positioning.
Background technique
TCD,transcranial Doppler stimulation as a kind of novel neuromodulation technology, because with Noninvasive, spatial resolution height, can The features such as realizing deep stimulation is attracting more and more attention of people.It and is mutual to tissue application is stimulated through the stimulation of cranium magnetosonic Perpendicular ultrasound and magnetic field are coefficient as a result, being the Hall effect occurred in the tissue for having certain electric conductivity.Its principle It is that the charged particle being stimulated in tissue vibrates under the action of ultrasonic wave, and then cutting magnetic line generates induction field, Direct regulation and control is carried out to neural electrical activity.It is compounded with ultrasound stimulation and electro photoluminescence through the stimulation of cranium magnetosonic, can produce has ultrasound The electro photoluminescence of high focusing has unique advantage in terms of neuromodulation.
The effect stimulated through cranium magnetosonic unique advantage because of its focusing generates the accurate positioning for focusing ultrasound stimulation target spot Property is the guarantee through cranium magnetosonic stimulation effect.
Summary of the invention
The technical problem to be solved by the invention is to provide one kind, and focal zone intensity and model at stimulation target spot may be implemented The ultrasonic transducer bracket for toy through cranium magnetosonic stimulation precise positioning of the control accurate enclosed.
The technical scheme adopted by the invention is that: a kind of ultrasonic transduction for toy through cranium magnetosonic stimulation precise positioning Device bracket includes firm banking, and the Z axis support group for being able to carry out vertical adjustment is vertically installed on the firm banking The upper end of part, the Z axis support arm is horizontally disposed by the connection of the first cruciform fastening for falsework and is able to carry out the support of the X-axis of Level tune The other end of one end of arm, the X-axis support arm connects the energy converter for fixing ultrasonic transducer by the second cruciform fastening for falsework Fixation kit.
The Z axis support component includes: the fixed adjusting collet on the fixed base in bottom end, the adjusting collet Upper end is provided with the scale for adjusting height inserted with the Z axis support arm that can be moved up and down on the Z axis support arm, It is threaded with after the height that Z axis support arm adjusts to setting on the side wall for adjusting collet, Z axis support arm is consolidated The first fixed fixed screw, the upper end of the Z axis support arm connect one end of X-axis support arm by the first cruciform fastening for falsework.
First cruciform fastening for falsework includes the first columnar body, is respectively formed with and is used in first columnar body Through the laterally inserted hole of X-axis support arm one end and being longitudinally inserted into for the Z axis support arm upper end in Z axis support component Hole, and setting corresponding with the laterally inserted hole for making the first columnar body and X-axis support arm is fixed to each other Second fixed screw, and with it is described be longitudinally inserted into the corresponding setting in hole for making the first columnar body and Z axis support arm End is fixed and adjusts the third fixed screw of the first columnar body rotation angle.
The scale for being laterally adjusted is provided on the X-axis support arm.
Second cruciform fastening for falsework includes the second columnar body, the use being horizontally formed in second columnar body In the horizontal through hole for running through the X-axis support arm, setting corresponding with the horizontal through hole is used to make the second columnar body The 4th fixed screw being fixed to each other with the X-axis support arm, the neighbouring horizontal through hole in second columnar body Side is longitudinally formed with the insertion of the energy converter fixation kit for installing energy converter fixation kit hole, solid with the energy converter Determine the corresponding setting of module insertion aperture for making the second columnar body and the energy converter fixation kit is fixed to each other the Five fixed screws.
The energy converter fixation kit includes the energy converter fixes sleeve for installing ultrasonic transducer, for clamping The energy converter fixture of energy converter fixes sleeve, be integrally formed in energy converter fixture top for being inserted into the second cross buckle The energy converter fixture mounting post that the energy converter fixation kit of part inserts in the hole, and for being inserted in the energy converter fixation kit Enter the fixture nut that the upper port in hole is threadedly coupled with the top of the energy converter fixture mounting post, wherein the transducing Device fixture mounting post also passes through the 5th fixed screw in the second cruciform fastening for falsework and is fixed to each other with second columnar body.
A kind of ultrasonic transducer bracket for toy through cranium magnetosonic stimulation precise positioning of the invention, can be by changing The movement and rotation of energy device bracket realize the accurate focusing regulation stimulated through cranium magnetosonic, focal zone at stimulation target spot may be implemented The control accurate of domain intensity and range, it is easy to operate, it is easy to use.It can be used for the high focusing nerve modulation of precise positioning, Precise positioning stimulation to stimulate through cranium magnetosonic provides a kind of feasible method.
Detailed description of the invention
Fig. 1 is that the overall structure of ultrasonic transducer bracket of the present invention for toy through cranium magnetosonic stimulation precise positioning is shown It is intended to;
Fig. 2 is the schematic perspective view after Fig. 1 rotates by a certain angle;
Fig. 3 is the structural schematic diagram of Z axis support component in the present invention;
Fig. 4 is the structural schematic diagram of the first cruciform fastening for falsework in the present invention;
Fig. 5 is the structural schematic diagram of the second cruciform fastening for falsework in the present invention;
Fig. 6 is the structural schematic diagram of energy converter fixation kit and the assembling of the second cruciform fastening for falsework in the present invention;
Fig. 7 is the structural schematic diagram of energy converter fixes sleeve in the present invention;
Fig. 8 is that the present invention illustrates for toy through the ultrasonic transducer stent applications state of cranium magnetosonic stimulation precise positioning Figure.
In figure
1: firm banking 2:Z axis support component
2.1: adjusting collet 2.2:Z axis support arm
2.3: the first fixed screw, 3: the first cruciform fastening for falsework
3.1: the first columnar bodies 3.2: laterally inserted hole
3.3: being longitudinally inserted into hole 3.4: third fixed screw
3.5: the second fixed screw 4:X axis support arms
5: the second cruciform fastening for falsework, 5.1: the second columnar body
5.2: 5.3: the four fixed screw of horizontal through hole
5.4: energy converter fixation kit is inserted into 5.5: the five fixed screw of hole
6: energy converter fixation kit 6.1: energy converter fixes sleeve
6.2: energy converter fixture 6.3: energy converter fixture mounting post
6.4: fixture nut 6.5: positive stop lug boss
11: ultrasonic action module 12: ultrasonic transduction module
13: subject toy 14: stereotaxic apparatus
15: ultrasonic transducer bracket 16: static magnet
17: mobile rotating device
Specific embodiment
Below with reference to embodiment and attached drawing to a kind of surpassing through cranium magnetosonic stimulation precise positioning for toy of the invention Sonic transducer bracket is described in detail.
As shown in Figure 1 and Figure 2, a kind of ultrasonic transducer for toy through cranium magnetosonic stimulation precise positioning of the invention Bracket includes firm banking 1, and the Z axis support component for being able to carry out vertical adjustment is vertically installed on the firm banking 1 2, the upper end of the Z axis support arm 2 is horizontally disposed by the connection of the first cruciform fastening for falsework 3 and is able to carry out the X-axis branch of Level tune The other end of one end of brace 4, the X-axis support arm 4 is connected by the second cruciform fastening for falsework 5 for fixing changing for ultrasonic transducer Can device fixation kit 6, the scale for being laterally adjusted is provided on the X-axis support arm 4.
As shown in figure 3, the Z axis support component 2 includes: bottom end is fixed on the adjusting collet on firm banking 1 2.1, the upper end for adjusting collet 2.1 is inserted with the Z axis support arm 2.2 that can be moved up and down, the Z axis support arm 2.2 On be provided with scale for adjusting height, be threaded on the side wall for adjusting collet 2.1 and adjusted in Z axis support arm 2.2 After the height for saving setting, to the first fixed screw 2.3 that Z axis support arm 2.2 is fixed, the Z axis support arm 2.2 it is upper End connects one end of X-axis support arm 4 by the first cruciform fastening for falsework 3.
As shown in figure 4, first cruciform fastening for falsework 3 includes the first columnar body 3.1, first columnar body It is respectively formed on 3.1 for through the laterally inserted hole 3.2 of 4 one end of X-axis support arm and in Z axis support component 2 2.2 upper end of Z axis support arm be longitudinally inserted into hole 3.3, and setting corresponding with the laterally inserted hole 3.2 for making The second fixed screw 3.5 that first columnar body 3.1 is fixed to each other with X-axis support arm 4, and hole 3.3 is longitudinally inserted into described Corresponding setting is used to make the first columnar body 3.1 to be fixed and adjust the first column master with 2.2 upper end of Z axis support arm The third fixed screw 3.4 of the rotation angle of body 3.1.
As shown in figure 5, second cruciform fastening for falsework 5 includes the second columnar body 5.1, it is horizontally formed on described second The horizontal through hole 5.2 being used for through the X-axis support arm 4 in columnar body 5.1, it is corresponding with the horizontal through hole 5.2 The 4th fixed screw 5.3 for making the second columnar body 5.1 and the X-axis support arm 4 be fixed to each other being arranged, described the The side of the neighbouring horizontal through hole 5.2 is longitudinally formed with for installing the energy converter fixation kit 6 in two columnar bodies 5.1 Energy converter fixation kit be inserted into hole 5.4, with the energy converter fixation kit corresponding setting in insertion hole 5.4 for making second The 5th fixed screw 5.5 that columnar body 5.1 and the energy converter fixation kit 6 are fixed to each other.
As shown in Figure 6, Figure 7, the energy converter fixation kit 6 includes solid for installing the energy converter of ultrasonic transducer Determine sleeve 6.1, for clamping the energy converter fixture 6.2 of energy converter fixes sleeve 6.1, is integrally formed in the energy converter fixture Energy converter fixture mounting post in the energy converter fixation kit insertion hole 5.4 for being inserted into the second cruciform fastening for falsework 5 on 6.2 tops 6.3, and for the upper port and the energy converter fixture mounting post in the energy converter fixation kit insertion hole 5.4 The fixture nut 6.4 that 6.3 top is threadedly coupled, wherein the energy converter fixture mounting post 6.3 also passes through the second cross buckle The 5th fixed screw 5.5 in part 5 is fixed to each other with second columnar body 5.1.The energy converter fixes sleeve 6.1 The positive stop lug boss 6.5 of position-limiting action from outside is formed with one week, passes through the rotatable transducer fixes sleeve in energy converter fixture 6.2 6.1, it can reach and adjust ultrasonic transducer vertical angle.
A kind of ultrasonic transducer bracket for toy through cranium magnetosonic stimulation precise positioning of the invention, can make ultrasound Energy converter is translated in X-direction, is moved up and down in Z-direction, precision 1mm;0~90 °, 0~90 ° of vertical rotary can be rotated horizontally, from And it can be realized the accurate stimulation to toy.
Fig. 8 is a kind of application of ultrasonic transducer bracket for toy through cranium magnetosonic stimulation precise positioning of the invention Example.As shown, subject toy 13 is fixed on the heating cushion of stereotaxic apparatus 14.By two functions being sequentially connected The ultrasonic action module 11 that signal generator and power amplifier are constituted generates specific ultrasonic excitation signal, by ultrasonic transducer The ultrasonic transduction module 12 constituted with the sound collimator for being connected to ultrasonic transducer bottom end is supported on one kind of the invention and is used for On ultrasonic transducer bracket 15 of the toy through cranium magnetosonic stimulation precise positioning, ultrasonic action electric signal is converted into acoustical signal, And vertically it is targeted to the stimulated zone of subject toy 13;The mobile rotating device 17 for being mounted with static magnet 16 drives static magnet 16 It is moved to 13 front side of subject toy, and makes static magnet 16 is mobile to be placed in 13 front of subject toy, is realized through cranium magnetosonic coupling Close electro photoluminescence.
When needing makes ultrasonic transducer rotate horizontally 0~90 °, the first cross buckle is adjusted by third fixed screw 3.4 Rotation angle between part 3 and X-axis support arm 4;When needing to make 0~90 ° of ultrasonic transducer vertical rotary, pass through the 5th Fixed screw 5.5 adjusts the rotation angle between the second cruciform fastening for falsework 5 and energy converter fixation kit 6.Either pass through rotation Turn energy converter fixes sleeve 6.1 and reaches adjusting ultrasonic transducer vertical angle.When needing to adjust the height of ultrasonic transducer, lead to It crosses the first fixed screw 2.3 adjustment X-axis support arm 4 and is inserted into the depth adjusted in collet 2.1;It is changed when needing to adjust ultrasound When energy device people lateral position, passes through the second fixed screw 3.5 or the 4th fixed screw 5.3 adjusts the first cruciform fastening for falsework 3 or the second Left-right position on the X-axis support arm 4 of cruciform fastening for falsework 5.

Claims (6)

1. a kind of ultrasonic transducer bracket for toy through cranium magnetosonic stimulation precise positioning, includes firm banking (1), It is characterized in that, the Z axis support component (2) for being able to carry out vertical adjustment, the Z is vertically installed on the firm banking (1) The upper end of axis support arm (2) is horizontally disposed by the first cruciform fastening for falsework (3) connection and is able to carry out the X-axis support arm of Level tune (4) other end of one end, the X-axis support arm (4) is connected by the second cruciform fastening for falsework (5) for fixing ultrasonic transducer Energy converter fixation kit (6).
2. a kind of ultrasonic transducer bracket for toy through cranium magnetosonic stimulation precise positioning according to claim 1, It is characterized in that, the Z axis support component (2) includes: bottom end is fixed on the adjusting collet (2.1) on firm banking (1), The upper end for adjusting collet (2.1) is inserted with the Z axis support arm (2.2) that can be moved up and down, the Z axis support arm (2.2) it is provided with the scale for adjusting height on, is threaded on the side wall for adjusting collet (2.1) and is supported in Z axis Arm (2.2) is adjusted to after the height of setting, to the first fixed screw (2.3) that Z axis support arm (2.2) is fixed, the Z axis One end that the upper end of support arm (2.2) passes through the first cruciform fastening for falsework (3) connection X-axis support arm (4).
3. a kind of ultrasonic transducer bracket for toy through cranium magnetosonic stimulation precise positioning according to claim 1, It is characterized in that, first cruciform fastening for falsework (3) includes the first columnar body (3.1), first columnar body (3.1) On be respectively formed with for the laterally inserted hole (3.2) through X-axis support arm (4) one end and for through Z axis support component (2) In Z axis support arm (2.2) upper end be longitudinally inserted into hole (3.3), and corresponding with laterally inserted hole (3.2) setting The second fixed screw (3.5) for making the first columnar body (3.1) and X-axis support arm (4) are fixed to each other, and with it is described Be longitudinally inserted into hole (3.3) corresponding setting for making the first columnar body (3.1) and Z axis support arm (2.2) upper end is consolidated Fixed and adjustment the first columnar body (3.1) rotation angle third fixed screw (3.4).
4. a kind of ultrasonic transducer bracket for toy through cranium magnetosonic stimulation precise positioning according to claim 3, It is characterized in that, being provided with the scale for being laterally adjusted on the X-axis support arm (4).
5. a kind of ultrasonic transducer bracket for toy through cranium magnetosonic stimulation precise positioning according to claim 1, It is characterized in that, second cruciform fastening for falsework (5) includes the second columnar body (5.1), it is horizontally formed on second column The horizontal through hole (5.2) being used for through the X-axis support arm (4) in shape main body (5.1), with the horizontal through hole (5.2) The 4th fixed screw for making the second columnar body (5.1) and the X-axis support arm (4) be fixed to each other of corresponding setting (5.3), the side of neighbouring horizontal through hole (5.2) is longitudinally formed with for installing on second columnar body (5.1) Energy converter fixation kit insertion hole (5.4) for stating energy converter fixation kit (6) is inserted into hole with the energy converter fixation kit (5.4) corresponding setting for making the second columnar body (5.1) and the energy converter fixation kit (6) is fixed to each other the Five fixed screws (5.5).
6. a kind of ultrasonic transducer bracket for toy through cranium magnetosonic stimulation precise positioning according to claim 1, It is characterized in that, the energy converter fixation kit (6) includes the energy converter fixes sleeve for installing ultrasonic transducer (6.1), for clamping the energy converter fixture (6.2) of energy converter fixes sleeve (6.1), it is integrally formed in the energy converter fixture (6.2) the energy converter fixture in energy converter fixation kit insertion hole (5.4) for being inserted into the second cruciform fastening for falsework (5) on top Mounting post (6.3), and for being pressed from both sides in the upper port of energy converter fixation kit insertion hole (5.4) and the energy converter Has the fixture nut (6.4) that the top of mounting post (6.3) is threadedly coupled, wherein the energy converter fixture mounting post (6.3) is also It is fixed to each other by the 5th fixed screw (5.5) in the second cruciform fastening for falsework (5) with second columnar body (5.1).
CN201811050561.7A 2018-09-07 2018-09-07 Ultrasonic transducer support for accurate positioning of small animal through transcranial magnetic acoustic stimulation Active CN109157744B (en)

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CN110559564A (en) * 2019-09-02 2019-12-13 深圳先进技术研究院 ultrasonic stimulation method and device
CN110639134A (en) * 2019-09-30 2020-01-03 秦皇岛市第一医院 Ultrasonic probe adjusting device, ultrasonic probe adjusting method and transcranial nerve stimulator
CN113101524A (en) * 2021-04-12 2021-07-13 中国医学科学院生物医学工程研究所 Transcranial magnetoacoustic stimulation device capable of flexibly realizing vector stimulation of whole brain area
CN113350707A (en) * 2021-05-31 2021-09-07 李磊 Device for ultrasonically stimulating nerve tissues
CN113559425A (en) * 2021-07-29 2021-10-29 陕西师范大学 Focused ultrasound regulation and control device and method for positioning stimulation of brain functional region of small animal
CN113729716A (en) * 2021-09-30 2021-12-03 中国医学科学院生物医学工程研究所 Magnetic-acoustic imaging device for brain of small animal

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CN113559425A (en) * 2021-07-29 2021-10-29 陕西师范大学 Focused ultrasound regulation and control device and method for positioning stimulation of brain functional region of small animal
CN113729716A (en) * 2021-09-30 2021-12-03 中国医学科学院生物医学工程研究所 Magnetic-acoustic imaging device for brain of small animal

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