CN109157434A - Lotion and preparation method thereof after a kind of antipruritic moisturizing bath - Google Patents
Lotion and preparation method thereof after a kind of antipruritic moisturizing bath Download PDFInfo
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- CN109157434A CN109157434A CN201810988704.2A CN201810988704A CN109157434A CN 109157434 A CN109157434 A CN 109157434A CN 201810988704 A CN201810988704 A CN 201810988704A CN 109157434 A CN109157434 A CN 109157434A
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- lotion
- water phase
- oil
- antipruritic
- allantoin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Abstract
The invention discloses lotions after a kind of antipruritic moisturizing bath and preparation method thereof, it includes each raw material components of following weight percent: oil phase component: O/W type emulsifier 0.1-3%, No. 15 white oil 1-6%, silicone oil 0.1-5%, mango seed rouge 1-6%, phytosterin ester 0.5-5%, 16/18 alcohol 0.1-2%, vitamin V E0.1-1.0%；Water phase components: deionized water polishing to 100%, glycerol 0.1-10%, propylene glycol 0.1-5%, carbomer 0.1-2%, allantoin 0.1-0.5%, preservative 0.5%, pH value adjustment agent 0.1-2%.Lotion can alleviated to a certain degree because seasonal variations, dry skin dehydration, using alkaline soap or because pruritis caused by undergarment after the antipruritic moisturizing bath of the rouge of seed containing mango of the invention, allantoin and phytosterin ester.
Description
Technical field
The present invention relates to daily chemical product technical field, in particular to lotion and its preparation side after a kind of antipruritic moisturizing bath
Method.
Background technique
In the life of growing tension, the reason of crowd of pruitus is more and more, cutaneous pruritus, has very much, excludes
Related with certain diseases, the pruitus as caused by diabetes, hepatopathy, nephrosis etc., there are also some extraneous factors:
1, such as the dry skin of autumn and winter, the moisture of body are just easy to be lost, the skin scabies of the more people of the overwhelming majority
Exactly because skin water shortage of itching and caused by.
2, alkaline soap: many people wash one's face in life commonly using soap, but many soap are all containing basic species
Matter is biggish, it is easy to just cause pruitus.
3, the personal clothing such as underwear: many people like wearing the nylon either biggish underwear of fiber-like in life now
Object, but this undergarment often causes cutaneous pruritus, it is comfortable still to wear cotton substance in fact.
In order to cope with pruitus problem, people take drug generally to treat or by laundry, take a shower and have a bath
Etc. modes alleviate pruitus problem.It is unfavorable by drug due to causing the factor of pruitus to be difficult to eliminate in life
In human health, people can more select laundry and the mode having a bath of taking a shower, although the day of existing shower cream series
Some components for pruitus of drawing up can also be added by changing product, but consider to cause the outer of pruitus comprehensively due to no
The problem of boundary's factor, from being unable to effectively comprehensively cope with pruitus problem caused by above-mentioned factor.
Main contents
The technical problem to be solved in the present invention is to provide lotions after a kind of antipruritic moisturizing bath and preparation method thereof, pass through mango
The perfect combination of seed rouge, allantoin and phytosterin ester these three raw materials nourishes from skin moisture-keeping, is confrontation pachylosis, anti-inflammatory
Sterilization helps to repair keratoderma, rebuilds the antipruritic profit body dew developed from the aspect of skin barrier, can solve non-disease enough
Pruitus problem caused by rationality.
In order to solve the above-mentioned technical problem, the present invention using the basic ideas of technical solution be select it is certain moisten, moisturizing,
Anti-inflammatory, mango seed rouge, phytosterin ester and the allantoin of repairing cuticula and other moisture retention raw materials compounding, after a kind of bath is made
Lotion achievees the purpose that antipruritic moisturizing.
Specifically, the present invention provides lotion after a kind of antipruritic moisturizing bath, it includes each raw materials of following weight percent
Component:
Oil phase component:
O/W type emulsifier 0.1-3%；
15# white oil 1-6%；
Silicone oil 0.1-5%；
Mango seed rouge 1-6%；
Phytosterin ester 0.5-5%；
Oil phase thickeners 0.1-2%；
Vitamin E (Ve) 0.1-1.0%；
Water phase components:
Deionized water polishing is to 100%；
Water phase moisturizer 0.2-15%；
Water phase thickener 0.1-2%；
Allantoin 0.1-0.5%；
PH value adjustment agent 0.1-2%；
Preservative 0.5%；
Essence 0.01%.
Further, the O/W type emulsifier is methyl sesquistearate, PEG-20 methyl times semi-solid fat
Acid esters group co-emulsifier.
Further, the silicone oil is DC345 silicone oil.
Further, the oil phase thickeners are 16/18 alcohol.
Further, the water phase moisturizer includes:
Glycerol 0.1-10%；
Propylene glycol 0.1-5%.
Further, the water phase thickener is carbomer.
Further, the PH regulator is triethanolamine.
Further, the preservative is methyl hydroxybenzoate, 4 kinds of Nipasol, Sensiva SC50, Phenoxyethanol components are mixed
Close preservative.Preferably Germany Shu Mei Euxyl K350 cosmetics top grade preservative.
Another aspect of the present invention, in order to prepare the antipruritic moisturizing of the above-mentioned rouge of seed containing mango, allantoin and phytosterin ester
Lotion after bath, the present invention also provides a kind of preparation methods of lotion after antipruritic moisturizing bath, the described method comprises the following steps:
S101, recipe ingredient is prepared: oil phase component: O/W type emulsifier 0.1-3%, No. 15 white oil 1-6%, silicone oil 0.1-
5%, mango seed rouge 1-6%, phytosterin ester 0.5-5%, 16/18 alcohol 0.1-2%, vitamin E 0.1-1.0%；Water phase components:
Deionized water polishing to 100%, glycerol 0.1-10%, propylene glycol 0.1-5%, carbomer 0.1-2%, allantoin 0.1-0.5%,
Preservative 0.5%, pH value adjustment agent 0.1-2%, essence 0.01%.
S102, by oil phase component: O/W type emulsifier 0.1-3%, No. 15 white oil 1-6%, silicone oil 0.1-5%, mango seed rouge
1-6%, phytosterin ester 0.5-5%, 16/18 alcohol 0.1-2%, vitamin E 0.1-1.0% are sequentially added to be heated in oily phase pot
Stirring and dissolving is to 85 DEG C；
S103, water phase components: deionized water polishing to 100%, glycerol 0.1-10%, propylene glycol 0.1-5%, carbomer
0.1-2% sequentially adds heating stirring in water phase pot and is dissolved to 85 DEG C；
S104, the water phase components in the oil phase component and water phase pot in oily phase pot are added in emulsion pot, and stir homogeneous
5-8min is uniformly mixed to oil phase component and water phase components；
S105, continue stirring and be cooled to 60 DEG C, pH value adjustment agent 0.1-2% is added, essence is added when being down to 45 DEG C in temperature
0.01%, preservative 0.5% simultaneously stirs evenly.
S106, stand 2 hours it is filling after the assay was approved.
For achieve the purpose that it is above solve the problems, such as, inventive formulation is from raw material selection, production technology, technical parameter etc.
It deployed, controlled.
Specifically, lotion after the antipruritic moisturizing bath of the rouge of seed containing mango, allantoin and phytosterin ester of the technical program
Antipruritic moisturizing raw material is mainly made of mango seed rouge, phytosterin ester, allantoin, and wherein mango seed rouge is a kind of natural moisturizing
Agent, antioxidant, vitamin A and E rich in, can soften, releive, nourishes rough skin, prevention eczema, insect bite and toxicodendron；
Since it is high not saponified with wound healing and power of regeneration；Various fatty acid are provided, skin is helped to keep soft and soft
It is suitable, help to reduce microgroove and wrinkle, effectively antagonizes rough skin.
Phytosterin ester on the skin the effect of: the lacking of Stratum corneum lipids, can cause moisture of skin to transmit obstacle, and
Cause to have dry skin, dry skin can cause a series of skin problem, and phytosterin ester is by repairing lipid layer to reach
From the effect of inside water conservation, keeps skin internal moisture sufficient, keep cell high moisture environments, make itself generation of basal confluent monolayer cells
It thanks actively, to accelerate the update of skin surface cell；Monomer component cupreol ester in phytosterin ester has good
Antiphlogistic effects can assist skin to eliminate bacteria breed and skin as non-hormone substance migration no dependence and irritation
Inflammatory problems caused by inner metabolism disorder.
Allantoin is used as cosmetics of super quality raw material, can promote epidermal growth, the effect for making wound heal rapidly；It can make skin
Skin is soft, crease-resistant and high resilience, has gloss, also have be protected from light, sterilize, anti-corrosion, analgesic, deodorization, antioxidation.
Mango seed rouge, allantoin and phytosterin ester nourish, confrontation pachylosis, anti-inflammatory sterilization, reparation from skin moisture-keeping
Keratoderma, rebuild these three raw materials of skin barrier form a perfect combination.
Specific embodiment
Specific embodiments of the present invention will be further explained below.It should be noted that for these implementations
The explanation of mode is used to help understand the present invention, but and does not constitute a limitation of the invention.In addition, invention described below
Technical characteristic involved in each embodiment can be combined with each other as long as they do not conflict with each other.
The present invention provides lotion after a kind of antipruritic moisturizing of rouge of seed containing mango, allantoin and phytosterin ester bath, packets
Each raw material component containing following weight percent:
Oil phase component: O/W type emulsifier 0.1-3%, No. 15 white oil 1-6%, silicone oil 0.1-5%, mango seed rouge 1-6%,
Phytosterin ester 0.5-5%, 16/18 alcohol 0.1-2%, vitamin V e 0.1-1.0%；Water phase components: deionized water polishing is extremely
100%, glycerol 0.1-10%, propylene glycol 0.1-5%, carbomer 0.1-2%, allantoin 0.1-0.5%, preservative 0.5%, PH
It is worth regulator 0.1-2%, essence 0.01%.
Lotion after the antipruritic moisturizing made of above various components of test of many times selection is bathed, (40 DEG C of heat stabilization test
30 days) it is thicker without being layered；It is thicker without being layered that cold stability tests (- 5 DEG C, 30 days)；Centrifugal test (2000 revolutions per seconds of 30min) nothing
Layering, is illustrated by taking 5 embodiments as an example below, and wherein the gross mass of component is subject to 100g.
Embodiment 1
Lotion after a kind of antipruritic moisturizing bath that embodiment 1 provides, it includes each raw material components of following weight percent:
Oil phase component: O/W type emulsifier 3%, No. 15 white oils 3%, silicone oil 3%, mango seed rouge 0.5%, phytosterin ester
0.5%, 16/18 alcohol 1%, vitamin V e 0.5%；Water phase components: deionized water 79.59%, glycerol 5%, propylene glycol 3%, card
Wave nurse 0.15%, allantoin 0.1%, preservative 0.5%, pH value adjustment agent 0.15%, essence 0.01%.
The preparation method of lotion after the antipruritic moisturizing bath of the rouge of seed containing mango, allantoin and phytosterin ester, specific as follows:
S101, recipe ingredient is prepared: oil phase component: O/W type emulsifier 3%, No. 15 white oils 3%, silicone oil 3%, mango seed
Rouge 0.5%, phytosterin ester 0.5%, 16/18 alcohol 1%, vitamin V e 0.5%；Water phase components: deionized water 79.59%,
Glycerol 5%, propylene glycol 3%, carbomer 0.15%, allantoin 0.1%, preservative 0.5%, pH value adjustment agent 0.15%, essence
0.01%.
S102, by oil phase component: O/W type emulsifier 3%, No. 15 white oils 3%, silicone oil 3%, mango seed rouge 0.5%, plant
Sterol ester 0.5%, 16/18 alcohol 1%, vitamin V e 0.5%；It sequentially adds heating stirring in oily phase pot and is dissolved to 85 DEG C；
S103, water phase components: deionized water 79.59%, glycerol 5%, propylene glycol 3%, carbomer 0.15%, allantoin
0.1%, it sequentially adds heating stirring in water phase pot and is dissolved to 85 DEG C；
S104, the water phase components in the oil phase component and water phase pot in oily phase pot are added in emulsion pot, and stir homogeneous
5-8min is to oil phase component and water phase components mixing homogeneous；
S105, continue stirring and be cooled to 60 DEG C, triethanolamine 0.15% is added, preservative K350 is added when being cooled to 45 DEG C
0.5% essence 0.01% simultaneously stirs evenly.
It is filling after S106, standing detection in 2 hours are qualified.
Embodiment 2
Lotion after the antipruritic moisturizing bath for a kind of rouge of seed containing mango, allantoin and the phytosterin ester that embodiment 2 provides, packet
Each raw material component containing following weight percent:
Oil phase component: O/W type emulsifier 3%, No. 15 white oils 3%, silicone oil 3%, mango seed rouge 1%, phytosterin ester
1%, 16/18 alcohol 1%, vitamin V e 0.5%；Water phase components: deionized water 78.59%, glycerol 5%, propylene glycol 3%, card wave
Nurse 0.15%, allantoin 0.1%, preservative 0.5%, pH value adjustment agent 0.15%, essence 0.01%.
The preparation method of lotion after the antipruritic moisturizing bath of the rouge of seed containing mango, allantoin and phytosterin ester, specific as follows:
S101, recipe ingredient is prepared: oil phase component: O/W type emulsifier 3%, No. 15 white oils 3%, silicone oil 3%, mango seed
Rouge 1%, phytosterin ester 1%, 16/18 alcohol 1%, vitamin V e 0.5%；Water phase components: deionized water 78.59%, glycerol
5%, propylene glycol 3%, carbomer 0.15%, allantoin 0.1%, preservative 0.5%, pH value adjustment agent 0.15%, essence
0.01%.
S102, by oil phase component: O/W type emulsifier 3%, No. 15 white oils 3%, silicone oil 3%, mango seed rouge 1%, plant steroid
Alcohol ester 1%, 16/18 alcohol 1%, vitamin V e 0.5%；It sequentially adds heating stirring in oily phase pot and is dissolved to 85 DEG C；
S103, water phase components: deionized water 78.59%, glycerol 5%, propylene glycol 3%, carbomer 0.15%, allantoin
0.1%, it sequentially adds heating stirring in water phase pot and is dissolved to 85 DEG C；
S104, the water phase components in the oil phase component and water phase pot in oily phase pot are added in emulsion pot, and stir homogeneous
5-8min is to oil phase component and water phase components mixing homogeneous；
S105, continue stirring and be cooled to 60 DEG C, triethanolamine 0.15% is added, preservative K350 is added when being cooled to 45 DEG C
0.5% essence 0.01% simultaneously stirs evenly.
It is filling after S106, standing detection in 2 hours are qualified.
Embodiment 3
Lotion after the antipruritic moisturizing bath for a kind of rouge of seed containing mango, allantoin and the phytosterin ester that embodiment 3 provides, packet
Each raw material component containing following weight percent:
Oil phase component: O/W type emulsifier 3%, No. 15 white oils 3%, silicone oil 3%, mango seed rouge 2%, phytosterin ester
1.5%, 16/18 alcohol 1%, vitamin V e 0.5%；Water phase components: deionized water 77.09%, glycerol 5%, propylene glycol 3%, card
Wave nurse 0.15%, allantoin 0.1%, preservative 0.5%, pH value adjustment agent 0.15%, essence 0.01%.
The preparation method of lotion after the antipruritic moisturizing bath of the rouge of seed containing mango, allantoin and phytosterin ester, specific as follows:
S101, recipe ingredient is prepared: oil phase component: O/W type emulsifier 3%, No. 15 white oils 3%, silicone oil 3%, mango seed
Rouge 2%, phytosterin ester 1.5%, 16/18 alcohol 1%, vitamin V e 0.5%；Water phase components: deionized water 77.09%, glycerol
5%, propylene glycol 3%, carbomer 0.15%, allantoin 0.1%, preservative 0.5%, pH value adjustment agent 0.15%, essence
0.01%.
S102, by oil phase component: O/W type emulsifier 3%, No. 15 white oils 3%, silicone oil 3%, mango seed rouge 2%, plant steroid
Alcohol ester 1.5%, 16/18 alcohol 1%, vitamin V e 0.5%；It sequentially adds heating stirring in oily phase pot and is dissolved to 85 DEG C；
S103, water phase components: deionized water 77.09%, glycerol 5%, propylene glycol 3%, carbomer 0.15%, allantoin
0.1%, it sequentially adds heating stirring in water phase pot and is dissolved to 85 DEG C；
S104, the water phase components in the oil phase component and water phase pot in oily phase pot are added in emulsion pot, and stir homogeneous
5-8min is to oil phase component and water phase components mixing homogeneous；
S105, continue stirring and be cooled to 60 DEG C, triethanolamine 0.15% is added, preservative K350 is added when being cooled to 45 DEG C
0.5% essence 0.01% simultaneously stirs evenly.
It is filling after S106, standing detection in 2 hours are qualified.
Embodiment 4
Lotion after the antipruritic moisturizing bath of a kind of rouge of seed containing mango of embodiment 4, allantoin and phytosterin ester, it includes with
The each raw material component of lower weight percent:
Oil phase component: O/W type emulsifier 3%, No. 15 white oils 3%, silicone oil 3%, mango seed rouge 2%, phytosterin ester
1.5%, 16/18 alcohol 1%, vitamin V e 0.5%；Water phase components: deionized water 76.94%, glycerol 5%, propylene glycol 3%, card
Wave nurse 0.15%, allantoin 0.25%, preservative 0.5%, pH value adjustment agent 0.15%, essence 0.01%.
The preparation method of lotion after the antipruritic moisturizing bath of the rouge of seed containing mango, allantoin and phytosterol, specific as follows:
S101, recipe ingredient is prepared: oil phase component: O/W type emulsifier 3%, No. 15 white oils 3%, silicone oil 3%, mango seed
Rouge 2%, phytosterin ester 1.5%, 16/18 alcohol 1%, vitamin V e 0.5%；Water phase components: deionized water 76.94%, glycerol
5%, propylene glycol 3%, carbomer 0.15%, allantoin 0.25%, preservative 0.5%, pH value adjustment agent 0.15%, essence
0.01%.
S102, by oil phase component: O/W type emulsifier 3%, No. 15 white oils 3%, silicone oil 3%, mango seed rouge 2%, plant steroid
Alcohol ester 1.5%, 16/18 alcohol 1%, vitamin V e 0.5%；It sequentially adds heating stirring in oily phase pot and is dissolved to 85 DEG C；
S103, water phase components: deionized water 76.94%, glycerol 5%, propylene glycol 3%, carbomer 0.15%, allantoin
0.25%, it sequentially adds heating stirring in water phase pot and is dissolved to 85 DEG C；
S104, the water phase components in the oil phase component and water phase pot in oily phase pot are added in emulsion pot, and stir homogeneous
5-8min is to oil phase component and water phase components mixing homogeneous；
S105, continue stirring and be cooled to 60 DEG C, triethanolamine 0.15% is added, preservative K350 is added when being cooled to 45 DEG C
0.5% essence 0.01% simultaneously stirs evenly.
It is filling after S106, standing detection in 2 hours are qualified.
Embodiment 5
Lotion after the antipruritic moisturizing bath of a kind of rouge of seed containing mango of embodiment 5, allantoin and phytosterin ester, it includes with
The each raw material component of lower weight percent:
Oil phase component: O/W type emulsifier 3%, No. 15 white oils 3%, silicone oil 3%, mango seed rouge 2%, phytosterin ester
1.5%, 16/18 alcohol 1%, vitamin V e 0.5%；Water phase components: deionized water 76.69%, glycerol 5%, propylene glycol 3%, card
Wave nurse 0.15%, allantoin 0.5%, preservative 0.5%, pH value adjustment agent 0.15%, essence 0.01%.
The preparation method of lotion after the antipruritic moisturizing bath of the rouge of seed containing mango, allantoin and phytosterol, specific as follows:
S101, recipe ingredient is prepared: oil phase component: O/W type emulsifier 3%, No. 15 white oils 3%, silicone oil 3%, mango seed
Rouge 2%, phytosterin ester 1.5%, 16/18 alcohol 1%, vitamin V e 0.5%；Water phase components: deionized water 76.69%, glycerol
5%, propylene glycol 3%, carbomer 0.15%, allantoin 0.5%, preservative 0.5%, pH value adjustment agent 0.15%, essence
0.01%.
S102, by oil phase component: O/W type emulsifier 3%, No. 15 white oils 3%, silicone oil 3%, mango seed rouge 2%, plant steroid
Alcohol ester 1.5%, 16/18 alcohol 1%, vitamin V e 0.5%；It sequentially adds heating stirring in oily phase pot and is dissolved to 85 DEG C；
S103, water phase components: deionized water 76.69%, glycerol 5%, propylene glycol 3%, carbomer 0.15%, allantoin
0.5%, it sequentially adds heating stirring in water phase pot and is dissolved to 85 DEG C；
S104, the water phase components in the oil phase component and water phase pot in oily phase pot are added in emulsion pot, and stir homogeneous
5-8min is to oil phase component and water phase components mixing homogeneous；
S105, continue stirring and be cooled to 60 DEG C, triethanolamine 0.15% is added, preservative K350 is added when being cooled to 45 DEG C
0.5% essence 0.01% simultaneously stirs evenly.
It is filling after S106, standing detection in 2 hours are qualified.
In addition, after the antipruritic moisturizing bath of the rouge of seed containing mango, allantoin and phytosterin ester in the preparation process of lotion, it is raw
Production should clean up agitated kettle, mixer and production apparatus before feeding intake, and sterilized, sterilized with 75% alcohol, ultraviolet light.It presses
Job instruction ingredient feeds intake, and lotion semi-finished product are sent to bottling department after laboratory inspection by sampling is qualified after antipruritic moisturizing bath
It carries out filling.The packaging materials such as bottle, lid, distributor (pump head) and packing apparatus enter between packing after ultraviolet light, ozonization
It uses.After cleaning, disinfection packing machine and conveyer, semi-finished product are carried out filling.Appearance and metering test are by Quality Inspector on duty
It examines, finished product examines qualified finished product that can be put in storage by laboratory inspection by sampling.Packaged qualification finished product transports finished room
Storage.
1, procedure for producing homogeneous controls: control temperature carries out homogeneous at 85 DEG C, homogenizing time control 5~8min it
Between, it stirs evenly.
2, filling quality controls: the packaging materials such as bottle, lid, distributor (pump head) and packing apparatus must be through ultraviolet lights, smelly
It is allowed for access between dispensing and uses after oxygen disinfection.Bottle placer and pipeline must can carry out after cleaned, disinfection (with 75% alcohol)
It is canned.The adjusting of canned amount is by Quality Inspector's inspection and supervision on duty；It can be carried out after canned FAA first article assurance normal canned.
Lotion after the antipruritic moisturizing bath of the rouge of seed containing mango, allantoin and phytosterol that above-described embodiment 1-5 is obtained is pressed
Experimental Comparison is carried out according to multiple indexs such as antipruritic, moisturizing, stability, the test parameters of acquisition is as shown in the table.
Following table is Emulsion Test after the antipruritic moisturizing of each rouge of seed containing mango of embodiment 1-5, allantoin and phytosterol is bathed
Testing result.
From table, it can be concluded that, the rouge of seed containing mango, allantoin and the phytosterin ester that technical solution of the present invention provides stop
Lotion is by selecting moist, moisturizing, anti-inflammatory, the grease for repairing cuticula and other moisture retention raw materials compounding, system after moisturizing of itching bath
At lotion after a kind of bath, reach the requirement of antipruritic moisturizing.
The present invention implements body and provides cream after the antipruritic moisturizing bath of the rouge of seed containing mango, allantoin and phytosterin ester a kind of
Liquid, antipruritic moisturizing raw material are mainly made of mango seed rouge, phytosterin ester, allantoin, and wherein mango seed rouge is a kind of natural
Emollient, antioxidant, vitamin A and E rich in, can soften, releive, nourishes rough skin, prevention eczema, insect bite and poison
Pueraria lobota；Since it is high not saponified with wound healing and power of regeneration；Various fatty acid are provided, help skin keep it is soft and
It is submissive, help to reduce microgroove and wrinkle, effectively antagonizes rough skin.
Lacking for Stratum corneum lipids can cause moisture of skin to transmit obstacle, and cause to have dry skin, and dry skin can cause
A series of skin problem, phytosterin ester achieve the effect that be retained from inside by repairing lipid layer, make inside skin
Moisture is sufficient, keeps cell high moisture environments, keeps basal confluent monolayer cells own metabolism active, so that it is thin to accelerate skin surface
The update of born of the same parents；Monomer component cupreol ester in phytosterin ester has good antiphlogistic effects, makes as non-hormone substance
With no dependence and irritation, skin can be assisted to eliminate inflammatory problems caused by bacteria breed and the disorder of skin inner metabolism.
Allantoin is used as cosmetics of super quality raw material, can promote epidermal growth, the effect for making wound heal rapidly；It can make skin
Skin is soft, crease-resistant and high resilience, has gloss, also have be protected from light, sterilize, anti-corrosion, analgesic, deodorization, antioxidation.Pass through
Test of many times, discovery can be helped by the antipruritic profit precursor emulsion of mango seed rouge, allantoin and phytosterin ester three's material combination
The cuticula for repairing skin provides enough skin and moistens degree, and auxiliary skin eliminates bacterium and nourishes to solve the non-pathology of skin
Property itch problem.
Above the embodiments of the present invention are described in detail, but the present invention is not limited to described embodiments.It is right
For those skilled in the art, in the case where not departing from the principle of the invention and spirit, these embodiments are carried out more
Kind change, modification, replacement and modification, still fall in protection scope of the present invention.
Claims (9)
1. lotion after a kind of antipruritic moisturizing bath, which is characterized in that the lotion includes each raw material component of following weight percent:
Oil phase component:
O/W type emulsifier 0.1-3%；
15# white oil 1-6%；
Silicone oil 0.1-5%；
Mango seed rouge 1-6%；
Phytosterin ester 0.5-5%；
Oil phase thickeners 0.1-2%；
Vitamin E 0.1-1.0%；
Water phase components:
Deionized water polishing is to 100%；
Water phase moisturizer 0.2-15%；
Water phase thickener 0.1-2%；
Allantoin 0.1-0.5%；
PH value adjustment agent 0.1-2%；
Preservative 0.5%；
Essence 0.01%.
2. lotion after a kind of antipruritic moisturizing bath according to claim 1, which is characterized in that the O/W type emulsifier is first
Base glucose sesquistearate, PEG-20 methyl sesquistearate group co-emulsifier.
3. lotion after a kind of antipruritic moisturizing bath according to claim 1, which is characterized in that the silicone oil is DC345 silicone oil.
4. lotion after a kind of antipruritic moisturizing bath according to claim 1, which is characterized in that the oil phase thickeners are 16/
18 alcohol.
5. lotion after a kind of antipruritic moisturizing bath according to claim 1, which is characterized in that the water phase moisturizer includes:
Glycerol 0.1-10%；
Propylene glycol 0.1-5%.
6. lotion after a kind of antipruritic moisturizing bath according to claim 1, which is characterized in that the water phase thickener is card wave
Nurse.
7. lotion after a kind of antipruritic moisturizing bath according to claim 1, which is characterized in that the PH regulator is three ethyl alcohol
Amine.
8. lotion after a kind of antipruritic moisturizing bath according to claim 1, which is characterized in that the preservative is oxybenzene first
4 kinds of ester, Nipasol, Sensiva SC50, Phenoxyethanol components mix preservative.
9. the preparation method of lotion, is used to prepare antipruritic as described in claim 1-8 any one after a kind of antipruritic moisturizing bath
Lotion after moisturizing bath, the described method comprises the following steps:
S101, recipe ingredient is prepared: oil phase component: O/W type emulsifier 0.1-3%, No. 15 white oil 1-6%, silicone oil 0.1-5%,
Mango seed rouge 1-6%, phytosterin ester 0.5-5%, 16/18 alcohol 0.1-2%, vitamin E 0.1-1.0%；Water phase components: it goes
Ionized water polishing is prevented to 100%, glycerol 0.1-10%, propylene glycol 0.1-5%, carbomer 0.1-2%, allantoin 0.1-0.5%
Rotten agent 0.5%, pH value adjustment agent 0.1-2%, essence 0.01%.
S102, by oil phase component: O/W type emulsifier 0.1-3%, No. 15 white oil 1-6%, silicone oil 0.1-5%, mango seed rouge 1-
6%, phytosterin ester 0.5-5%, 16/18 alcohol 0.1-2%, vitamin E 0.1-1.0% are sequentially added to heat in oily phase pot and be stirred
It mixes and is dissolved to 85 DEG C；
S103, water phase components: deionized water polishing to 100%, glycerol 0.1-10%, propylene glycol 0.1-5%, carbomer 0.1-
2%, which sequentially adds heating stirring in water phase pot, is dissolved to 85 DEG C；
S104, the water phase components in the oil phase component and water phase pot in oily phase pot are added in emulsion pot, and stir homogeneous 5-
8min is uniformly mixed to oil phase component and water phase components；
S105, continue stirring and be cooled to 60 DEG C, pH value adjustment agent 0.1-2% is added, essence is added when being down to 45 DEG C in temperature
0.01%, preservative 0.5% simultaneously stirs evenly.
S106, stand 2 hours it is filling after the assay was approved.
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2405068A1 (en) * | 1977-10-10 | 1979-05-04 | Sauba Lab | Water in oil emulsions for dry skin - contg. vitamin=A, stigmasterol, allantoin, and alpha tocopherol |
| EP1214051A1 (en) * | 1999-09-22 | 2002-06-19 | Laboratoires Pharmascience | Use of a vegetable oil product as agent for increasing skin lipid synthesis |
| CN101664371A (en) * | 2009-09-29 | 2010-03-10 | 广东名臣有限公司 | Acne treatment cosmetic composition |
| CN108079094A (en) * | 2017-12-29 | 2018-05-29 | 扬州中汇生物技术有限公司 | A kind of baby's itching-relieving cream and preparation method thereof |
| CN108403467A (en) * | 2018-05-16 | 2018-08-17 | 江苏远恒药业有限公司 | A kind of dimension E skin care milks formula and preparation process |
-
2018
- 2018-08-28 CN CN201810988704.2A patent/CN109157434A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2405068A1 (en) * | 1977-10-10 | 1979-05-04 | Sauba Lab | Water in oil emulsions for dry skin - contg. vitamin=A, stigmasterol, allantoin, and alpha tocopherol |
| EP1214051A1 (en) * | 1999-09-22 | 2002-06-19 | Laboratoires Pharmascience | Use of a vegetable oil product as agent for increasing skin lipid synthesis |
| CN101664371A (en) * | 2009-09-29 | 2010-03-10 | 广东名臣有限公司 | Acne treatment cosmetic composition |
| CN108079094A (en) * | 2017-12-29 | 2018-05-29 | 扬州中汇生物技术有限公司 | A kind of baby's itching-relieving cream and preparation method thereof |
| CN108403467A (en) * | 2018-05-16 | 2018-08-17 | 江苏远恒药业有限公司 | A kind of dimension E skin care milks formula and preparation process |
Non-Patent Citations (4)
| Title |
|---|
| 廖万青等: ""皮肤疾病源性瘙痒"", 《中国医学文摘（皮肤科学）》 * |
| 李成玲等: "《皮肤科合理用药》", 31 January 2009, 中国医药科技出版社 * |
| 王亮等: ""脂肪酶催化合成植物甾醇酯探讨"", 《生物技术世界》 * |
| 裘炳毅等: "《现代化妆品科学与技术》", 31 March 2016, 中国轻工业出版社 * |
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Address after: 518000 Guangdong city of Shenzhen province Qianhai Shenzhen Hong Kong cooperation zone before Bay Road No. 1 building 201 room A (located in Shenzhen Qianhai business secretary Co. Ltd.) Applicant after: Qianhai Huixi Technology (Shenzhen) Co., Ltd. Address before: 518000 Guangdong city of Shenzhen province Qianhai Shenzhen Hong Kong cooperation zone before Bay Road No. 1 building 201 room A (located in Shenzhen Qianhai business secretary Co. Ltd.) Applicant before: Shenzhen Qianhai Carl Jung Biotechnology (Group) Co., Ltd. |
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