CN113693971A - Moistening and nursing cream for moistening and nursing nipples of puerpera in lactation period - Google Patents

Moistening and nursing cream for moistening and nursing nipples of puerpera in lactation period Download PDF

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Publication number
CN113693971A
CN113693971A CN202111024748.1A CN202111024748A CN113693971A CN 113693971 A CN113693971 A CN 113693971A CN 202111024748 A CN202111024748 A CN 202111024748A CN 113693971 A CN113693971 A CN 113693971A
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China
Prior art keywords
nursing
skin
cream
nipple
moistening
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CN202111024748.1A
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Chinese (zh)
Inventor
钱颖
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Shanghai Canshi Biotechnology Co ltd
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Shanghai Canshi Biotechnology Co ltd
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Priority to CN202111024748.1A priority Critical patent/CN113693971A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31Hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/007Preparations for dry skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

Abstract

The invention discloses a moistening and nursing cream for moistening and nursing nipples of puerpera in lactation period, which relates to the technical field and comprises the following components in percentage by weight: 45-50% of sunflower seed oil, 28-33% of shea butter, 13-18% of PEG-8 beeswax, 4-9% of squalene, 0.5-1.0% of polyglycerol-3 ricinoleate and 0.05-0.15% of propyl gallate. The nipple cream can not only moisten the nipple skin, but also supplement cuticle sebum, relieve the itching and pain of nipples caused by the loss of the sebum of the nipple skin of puerpera in the lactation period, and play a role in preventing the nipple skin from chapping.

Description

Moistening and nursing cream for moistening and nursing nipples of puerpera in lactation period
Technical Field
The invention relates to the technical field of cosmetics, in particular to a moistening and nursing cream for moistening and nursing nipples of puerpera in a lactation period.
Background
When a lying-in woman feeds a baby in a lactation period, the breast feeding frequency is frequent, or the baby has an incorrect milk feeding posture, or the nipple is short, short and sunken in the day, the nipple sebum loss, the nipple is dry, itchy and painful, and even the nipple of the lying-in woman is cracked, and mastitis is caused by bacterial invasion.
At present, products for moistening and nursing nipples of puerperae in lactation period in the market mainly comprise two types:
one kind is animal sheep fat cream as main component: such as lanolin cream produced by brands Lansinoh and Medela, pure lanolin as an ingredient; for example, lanolin cream produced by Beijing brand contains 99.968% lanolin and 0.032% vitamin E, and can be used for moistening nipple skin and relieving nipple pain during lactation.
One is a plant cream as main component: for example, the nursing product of brand evereden comprises castor oil, sunflower oil, grape seed oil and rosa canina seed oil, and has the functions of moistening and repairing red, dry and itchy papilla skin; as for nursing products of the brand mamakids, the components of the nursing product are sunflower seed oil, corn oil and coconut oil, so that the nipples can be kept in a moist and soft state, mothers can conveniently nurse the nipples, and the nipple skin which is easy to dry in the lactation period is wrapped under the protective layer, so that the skin is prevented from being dry and rough; the brand Parma nipple repair cream comprises cocoa butter, vitamin B5 and vaseline, and can improve nipple moistening degree, relieve nipple discomfort, and relieve discomfort caused by baby watery mouth and nasal discharge; also, the skin-moistening cream is called Bella, and comprises organic shea extract, organic avocado extract, organic olive extract, organic aloe extract, natural cocoa butter and natural vitamin C, and can also moisten skin.
The nursing product taking the animal lanolin cream as the main component is a multi-component mixture of lipid substances secreted by sebaceous glands of sheep skin and adhered to woolen fleece, is recovered from wool washing liquid, and has the effects of softening the skin, preventing degreasing and chapping the skin; lanolin has a melting point of about 40 ℃, is a sticky substance, is not easy to apply, has a slight special odor, and has poor color. In addition, the alcohol compound of the lanolin cream is easy to cause allergy, and the reason for generating the allergy after the lanolin cream is mixed with human skin can be 'self-sensitization' similar to human skin; the insecticides in lanolin come from sheep-eaten grass, and although organochlorine insecticides are generally banned, they are still widely used in some countries, and further, the insecticides in lanolin are transferred into the body through human skin, and when the lanolin cream is applied to the mother's nipple, the baby may ingest directly into the mouth, presenting a health risk.
The nursing product with plant cream as main component can moisten nipple to avoid skin dryness and other discomfort. However, the problems of sebum loss, itching and pain and further chapping of the nipple skin caused by lactation are difficult to achieve the targeted prevention of the itching and chapping of the nipple skin.
Based on the problems, the moisturizing and nursing cream for moisturizing and nursing the nipples of the puerpera in the lactation period is designed to solve the problems.
Disclosure of Invention
The invention aims to solve the defects in the prior art and provides a moisturizing and nursing cream for moisturizing and nursing nipples of puerpera in lactation.
In order to achieve the purpose, the invention adopts the following technical scheme:
a moistening and nursing cream for moistening and nursing nipple of a puerpera in lactation period comprises the following components in percentage by weight:
45-50% of sunflower seed oil, 28-33% of shea butter, 13-18% of PEG-8 beeswax, 4-9% of squalene, 0.5-1.0% of polyglycerol-3 ricinoleate and 0.05-0.15% of propyl gallate.
Further, a method for preparing a moisturizing cream, comprising the steps of:
step 1), preparing sunflower seed oil, shea butter, PEG-8 beeswax, squalene and polyglycerol-3 ricinoleate to obtain a group A raw material, and preparing propyl gallate to obtain a group B raw material;
step 2), heating the group A raw materials to 80 ℃, and uniformly mixing to obtain a mixed raw material;
step 3), cooling the mixed raw material obtained in the step 2) to 38 ℃;
step 4), adding the raw materials in the group B into the mixed raw materials cooled in the step 3), uniformly mixing, and cooling to room temperature to obtain the moisturizing and nursing cream for moisturizing and nursing the nipples of the puerpera in the lactation period;
step 5), inspecting the semi-finished product;
and 6), canning, packaging, finishing and leaving factory.
Compared with the prior art, the invention has the following beneficial effects: the nipple skin moisturizing cream can not only achieve the effect of moistening the nipple skin, but also supplement the nipple skin sebum, relieve the nipple skin fat loss of puerperae in the lactation period, relieve the dryness, itching and pain and achieve the effect of preventing cracked nipples;
by adopting natural plant components, the natural plant components are mild in property, the shea butter and the sunflower seed oil can supplement unsaturated fatty acid required by the nipple skin, keep the nipple skin moist, relieve discomfort such as dryness, itching and pain of the nipple skin, and meanwhile, by combining the plant component squalene from olive oil, sebum lost in the nipple skin is effectively supplemented, moisture is kept, the skin is kept soft and healthy, the nipple is prevented from being cracked, and the nursing effect is remarkable.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely below, and it should be apparent that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments.
When a lying-in woman feeds a baby in a lactation period, frequent lactation is performed, or the baby has an incorrect milk feeding posture, or the nipple is short, small and sunken, nipple sebum loss, the nipple is dry and red, and even the nipple of the lying-in woman is cracked, and bacteria invade to cause mastitis.
Therefore, it is very important to moisten and care the nipples of the lying-in women during the lactation period.
The application provides a moistening and nursing cream for moistening and nursing the nipples of puerpera in the lactation period, which is used for moistening and nursing the skin of the nipples from the perspective of supplementing the sebum of the skin of the nipples so as to prevent the phenomenon of cracked nipples.
The lipids on the skin surface are composed of sebum secreted from sebaceous glands and lipids produced by the disintegration of keratinocytes (epidermal lipids). Sebum is also known as endogenous lipids, while epidermal lipids are known as exogenous lipids.
Generally, epidermal lipids contain phospholipids, are free of squalene and wax lipids, mostly cholesterol, 7-dehydrocholesterol and cholesterol sulfate, are respectively associated with synthetic vitamin D and keratin fibers, and also include fatty acids, most of which are Δ 9, and mostly C20 or more.
In sebum, the content of phospholipids is low, squalene and wax fat (which are the markers of sebaceous gland secretion) are contained, the content of cholesterol is low, most of fatty acids are basic carbon chains and branched chains, most of unsaturated fatty acids are delta 6, and most of unsaturated fatty acids are C14-C18 (the main component of triacylglycerol).
In the constitution of epidermal lipids and sebum, it was found that epidermal lipids contain almost no squalene, wax lipid and other components, while sebum contains squalene and wax lipid.
At the same time, the lipid composition at the surface of each human skin is relatively stable over life, with FFAs (free fatty acids) varying widely among individuals, and squalene, wax esters, cholesterol and cholesterol esters being substantially similar. Research shows that the percentage content of fatty acid and total triacylglycerol in normal sebum of people in China is obviously lower than that of western people, and the percentage content of squalene is obviously higher than that of western people.
The plant cream is extracted from plants, and the components mainly comprise unsaturated fatty acid. The plant-derived cream has clear and simple components, and can not generate the hidden trouble in the allergy aspect of complex components of the animal-derived mutton tallow cream.
Therefore, the plant cream is used as a main component, the squalene for supplementing sebum is used for raising, and the unsaturated fatty acid in the nipple skin is supplemented through the shea butter and the sunflower seed oil, so that the moisturizing and nursing cream for moisturizing and nursing the nipple of the puerpera in the lactation period is obtained.
Specifically, the moisturizing and nursing cream for moisturizing and nursing the nipples of the puerpera in the lactation period comprises the following components in percentage by weight:
45-50% of sunflower seed oil, 28-33% of shea butter, 13-18% of PEG-8 beeswax, 4-9% of squalene, 0.5-1.0% of polyglycerol-3 ricinoleate and 0.05-0.15% of propyl gallate.
Wherein the sunflower seed oil is used as a skin conditioner and extracted from sunflower seeds; the shea butter is extracted from shea butter fruit as skin conditioner; PEG-8 beeswax as an emulsifier; squalene as an emollient; polyglycerol-3 ricinoleate as an emulsifier; propyl gallate acts as an antioxidant.
The application also provides a method for preparing a moisturizing cream, comprising the steps of:
step 1), preparing sunflower seed oil, shea butter, PEG-8 beeswax, squalene and polyglycerol-3 ricinoleate to obtain a group A raw material, and preparing propyl gallate to obtain a group B raw material;
step 2), heating the group A raw materials to 80 ℃, and uniformly mixing to obtain a mixed raw material;
step 3), cooling the mixed raw material obtained in the step 2) to 38 ℃;
step 4), adding the raw materials in the group B into the mixed raw materials cooled in the step 3), uniformly mixing, and cooling to room temperature to obtain the moisturizing and nursing cream for moisturizing and nursing the nipples of the puerpera in the lactation period;
step 5), inspecting the semi-finished product;
and 6), canning, packaging, finishing and leaving factory.
The moistening and nursing cream obtained by the preparation method realizes the effects of moistening the nipple skin and preventing the nipple skin from chapping, and supplements the cuticle cortex to keep the skin deep and moist.
Wherein, the shea butter:
the avocado oil is derived from avocado, has weak hazelnut flavor, and has high safety to skin. The skin care product contains rich vitamins, sterols, lecithin and the like, has good nutrition and osmosis effects, fully nourishes skin, is very suitable for dry and aged skin, and particularly has good effects of preventing the dryness of pregnant women and preventing stretch marks.
Avocado extract is a high-quality raw material of cosmetics, contains a large amount of unsaturated fatty acids and abundant vitamins, particularly vitamin E and carotene, has strong attraction to ultraviolet rays, and is a high-quality raw material of skin-care and sun-proof cosmetics, and glyceride components in avocado fruit fat mainly comprise glycerol oleic acid distearate (45.9%), glycerol dioleate stearate (45.0%), glycerol oleic acid palm stearate, glycerol coconut palm stearate and glycerol trioleate (6.8%). The avocado extract is extracted from avocado fruits, has good moisturizing and moistening effects, can help skin lock moisture for a long time, deeply nourish skin, and improve the problem of dryness and roughness of skin, can enhance the metabolism of skin cells, and has the anti-aging effect; has the effects of inhibiting the activity of metalloproteinase, resisting inflammation of skin and being a good humectant. Is often applied to maintenance oil and repair face cream in winter.
The shea butter is used as a novel cosmetic raw material, the mass fraction of unsaponifiable matters in the shea butter is as high as 9-13 percent, which is not possessed by other vegetable oil, and the natural moisturizing factors in the shea butter and the moisturizing agent extracted from sebaceous glands have the same components, so that the shea butter becomes a natural vitamin A cream, and the shea butter is also regarded as the most effective natural skin moisturizing agent and conditioning agent, thereby being applied to beauty cream, milky lotion, water cream and other modified varieties to supplement the oil lacked in epidermal cells of human bodies and providing various basic elements required for maintaining the physiological balance of the skin.
The shea butter is applied to cosmetics, is used as an excellent humectant and conditioner, is an auxiliary agent with outstanding treatment efficacy, and has a plurality of unique uses. The vitamin A in the shea butter has important improvement effect on removing skin defect, such as ruffles, eczema and the like; the high-quality shea butter can be used for treating skin allergy, xerosis cutis, skin ulcer, skin inflammation, insect bite, skin burn, etc.
Sunflower seed oil:
sunflower seed, the fruit of sunflower. Sunflower seed oil is golden in color, clear and transparent, has faint scent, is important edible oil, contains a large amount of unsaturated fatty acid such as linoleic acid and the like which are necessary for human bodies, is a basic component for forming various cells, can promote the regeneration and growth of the cells of the human bodies, and protects the health of the skin.
The sunflower seed oil contains 90% of unsaturated fatty acid, and contains various substances beneficial to human body such as sterol, vitamin, linoleic acid, etc. Sunflower oil is a well-known health edible oil with a high content of linoleic acid, wherein the natural vitamin E content is highest in all major vegetable oils, and about 100-120 mg per hundred grams. Has good effect of delaying human cell aging. The linoleic acid content can reach about 70 percent.
The plant component skin conditioner prepared by combining the shea butter and the sunflower seed oil can supplement unsaturated fatty acid in the nipple skin, so that the nipple skin is kept moist, and the plant component skin conditioner has the advantages over animal component nursing products and does not have the problem of potential safety hazard.
Plant component squalene:
following deep-sea sharks, sebum is an animal tissue found to have a high squalene content. Sebum is fat secreted by sebaceous glands in human skin, and contains various chemical components such as triglyceride, diglyceride, favorable fatty acid, squalene, cholesterol and the like, wherein squalene is one of important functional components forming the sebum of the human body, the concentration of the squalene is extremely high in human fat cells, and 6% -14% of epidermal lipid components of the human are squalene. The squalene content of sebum is approximately 13g/100 g. The skin secretion of human body, namely sebum, maintains the soft and smooth skin due to the sterol and the squalene, and each human can secrete about 125-475 mg of squalene every day, wherein the highest scalp fat is particularly the highest, and the squalene content is about 6.4 times of cholesterol. As such, squalene is used as cosmetic raw material and has protecting and nourishing effects.
Squalene is an important component constituting sebum and at the same time provides nutrition to the skin. Squalene is also a moisturizing substance of the stratum corneum. Fetal sebum is reported to be a highly effective moisturizer, having a water retention effect on the stratum corneum. Squalene, when used in combination with triacylglycerols, cholesterol, ceramides and fatty acids, can produce a similar water retention effect as fetal sebum.
The composition can supplement sebum lost from papillary skin, and can be used for preventing cracked papillary after long-term use.
In conclusion, the moisturizing and nursing cream for moisturizing and nursing the nipples of the puerpera in the lactation period, which is obtained in the application, can not only supplement sebum loss caused by nipple skin loss, but also moisturize and nurse the nipple skin, relieve pain and prevent the nipple from being cracked.
Examples
46% of sunflower seed oil, 31% of shea butter, 16% of PEG-8 beeswax, 6.2% of squalene, 0.7% of polyglycerol-3 ricinoleate and 0.1% of propyl gallate. The moisturizing and nursing cream for moisturizing and nursing the nipples of the puerpera in the lactation period in example 1 is obtained.
Test examples
The moisturizing and conditioning cream for moisturizing and caring the nipples of the lactating parturients according to example 1 of the present invention was tested for the effects of alleviating and preventing the nipples from pain.
The test was performed in a test panel of 20 nursing subjects over the age of 30 and 3 nursing subjects between the ages of 20-30.
Test example 1: preventing cracked nipple.
The test subjects were divided into 2-9 points according to severity according to their papillary skin condition in the test panel, wherein 9 points represented very poor and an average score of 6.40 was obtained. The treatment cream of example 1 of the present application was used on the teats of all test subjects. The results of the evaluation of the use of all test subjects were recorded on days 1, 3 and 7, i.e. the average score of the teat skin condition of all test subjects on days 1, 3 and 7 using the cream, respectively, after 7 consecutive days of use.
The results of the evaluation are shown in Table 1.
Figure BDA0003242870780000101
The cream of example 1 of the present application was used for nipples of 18 lactation test subjects whose nipple skin condition score was 5 points or more. The use was continued for 7 days, and the results of the use evaluations of all test subjects were recorded on days 1, 3 and 7.
The results of the evaluation are shown in Table 2.
Figure BDA0003242870780000102
The above results show that the cream of example 1 of the present application can prevent the occurrence of cracked nipple.
Test example 2: relieving nipple pain.
The test subjects were classified into 2-10 points according to severity according to the nipple skin condition of the test subjects in the test group, wherein 10 points represent extreme pain, and an average score of 5.45 was obtained. The treatment cream of example 1 of the present application was used at the teats of all test subjects. The test subjects were recorded for 7 consecutive days of use, on day 1, day 3 and day 7, i.e. the average score of the teat skin condition was recorded for all test subjects on day 1, day 3 and day 7 of use of the cream, respectively.
The results of the use evaluation are shown in Table 3.
Figure BDA0003242870780000111
The cream of example 1 of the present application was used for nipples of 13 lactation test subjects having a nipple skin condition score of 5 or more. The use was continued for 7 days, and the results of the use evaluations of all test subjects were recorded on days 1, 3 and 7.
The results of the evaluation are shown in Table 4.
Figure BDA0003242870780000112
The above results indicate that the cream care of example 1 of the present application can play a role in alleviating the pain of the nipples.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and equivalent substitutions or changes according to the technical solution and the inventive concept of the present invention should be covered by the scope of the present invention.

Claims (2)

1. A moisturizing and nursing cream for moisturizing and nursing nipple of a puerpera in lactation period is characterized by comprising the following components in percentage by weight:
45-50% of sunflower seed oil, 28-33% of shea butter, 13-18% of PEG-8 beeswax, 4-9% of squalene, 0.5-1.0% of polyglycerol-3 ricinoleate and 0.05-0.15% of propyl gallate.
2. A method for preparing a moisturizing cream according to claim 1, comprising the steps of:
step 1), preparing sunflower seed oil, shea butter, PEG-8 beeswax, squalene and polyglycerol-3 ricinoleate to obtain a group A raw material, and preparing propyl gallate to obtain a group B raw material;
step 2), heating the group A raw materials to 80 ℃, and uniformly mixing to obtain a mixed raw material;
step 3), cooling the mixed raw material obtained in the step 2) to 38 ℃;
step 4), adding the raw materials in the group B into the mixed raw materials cooled in the step 3), uniformly mixing, and cooling to room temperature to obtain the moisturizing and nursing cream for moisturizing and nursing the nipples of the puerpera in the lactation period;
step 5), inspecting the semi-finished product;
and 6), canning, packaging, finishing and leaving factory.
CN202111024748.1A 2021-09-02 2021-09-02 Moistening and nursing cream for moistening and nursing nipples of puerpera in lactation period Pending CN113693971A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115645294A (en) * 2022-09-30 2023-01-31 露乐健康科技股份有限公司 Application of batyl alcohol in preparation of product for treating female nipple discomfort during lactation and product for treating female nipple discomfort during lactation

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
睦清: "哺乳妈妈还在用羊脂膏吗?", pages 1, Retrieved from the Internet <URL:https://www.xiaohongshu.com/explore/5dce657a0000000001006fe0> *
睦清母婴京东自营旗舰店: "商品评价图/视频部分", pages 1 - 2, Retrieved from the Internet <URL:https://item.jd.com/10070898159451.html#none> *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115645294A (en) * 2022-09-30 2023-01-31 露乐健康科技股份有限公司 Application of batyl alcohol in preparation of product for treating female nipple discomfort during lactation and product for treating female nipple discomfort during lactation

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