CN109528532A - A kind of skin care item and preparation method thereof containing choline vanillate - Google Patents
A kind of skin care item and preparation method thereof containing choline vanillate Download PDFInfo
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- CN109528532A CN109528532A CN201811592501.8A CN201811592501A CN109528532A CN 109528532 A CN109528532 A CN 109528532A CN 201811592501 A CN201811592501 A CN 201811592501A CN 109528532 A CN109528532 A CN 109528532A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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Abstract
The invention discloses a kind of skin care item and preparation method thereof containing choline vanillate, the raw material for preparing of the skin care item includes choline vanillate, moisturizer, emollient, skin conditioning agent, emulsifier, solvent, thickener, chelating agent and pH adjusting agent.Raw material will be prepared and be divided into A, B, C and D phase, as follows prepared by step: after S1, the processing that carries out disinfection to the first emulsion pot and the second emulsion pot, A phase raw material being added in the first emulsion pot, is stirred evenly after heating；S2, B phase raw material is added in the second emulsion pot, insulated and stirred；S3, B phase raw material is added in A phase raw material, when being added, homogeneous is stirred, and is kept in adition process integral into stablizing emulsus；S4,55~65 DEG C are cooled to, C phase raw material is added, stirs evenly；S5,35~45 DEG C are cooled to, D phase raw material is added, 5~15min of stirring stops stirring to after being uniformly dispersed, cools down up to the skin care item.
Description
Technical field
The present invention relates to daily chemicals fields, and in particular to a kind of skin care item and preparation method thereof containing choline vanillate.
Background technique
Skin care item have the function of skin maintenance and cosmetic benefits, can enhance the elasticity and vigor of skin, commonly using can make one it is young,
Beauty, skin care item have become the daily necessities of numerous people seeking beauties.Face cream is that the most important step of basic skin care is also usually
The final step of nutrition skin-protection.Face cream provides dual anti-aging effect, can stimulate cell neogenesis energy, while promoting collagen
Synthesis improves the texture and the colour of skin uniformity of skin surface, keeps skin more careful, meanwhile, also usually containing in face cream can provide
The Moringa of the filter system protection skin Antagonistic Environment pollution of SPF -15 (Sun Protection Factor, SPF15)
Essence keeps the direct injury of skin not light.The effective components such as the whitening and anti-aging in face cream can preferably be inhaled by skin
It receives.According to effect, face cream is broadly divided into three categories: moisturizing face cream, whitening cream and anti-aging face cream.The aqueous degree of moisturizing face cream
Height is easy to smear uniformly and rapid osmotic is to epidermis, is easy to be absorbed water conservation degree height；The ingredient of skin care can be allowed to be easy
It is persisted, it is not easy to be evaporated, maintain certain water content of skin, allow skin non-greasy, oil content is few, and there are also oil-controls
Effect.Whitening cream component requirements safety, non-stimulated, not spirituosity, mild, and also moistening effect will be got well；Especially part beauty
Bai Chengfen is oxidized easily, and therefore, whitening cream need to improve system stability.Anti-aging face cream requires moistening effect good, because
The good absorption that could promote aging ingredient of moistening effect；And moisturizing effect will be got well, and start the skin of aging in addition to moisture not
Except foot, oil also starts to reduce, and sufficiently moistening can just prevent wrinkle from generating；Aging ingredient mainly has Alphalin, collagen egg
It is white, win peptide and Q10 etc..However, the face cream class skin care item of whitening and anti-aging and moisture-keeping efficacy can be had both simultaneously in the prior art
It is also relatively fewer.
Choline is a kind of biostearin, while being also nutrient needed by human.It is the important component for constituting cell membrane,
It is also one of the raw material of human body synthesis glycine.It is separated first from pig's bile by Andreas Strecker within 1864,
It is synthesized chemically within 1866.The intracorporal choline of people, which has, greatly to be derived from food, and trimethylamine is broken down into large intestine.
Choline is a kind of strong organic base, is the constituent of lecithin, exists among sphingomyelin, is that body can be changed methyl
One source and the product for acting on synthesizing methyl, while being the precursor of acetylcholine again, it is also regarded as helping to mankind's brain
Development and memory.Human body can also synthesize choline, therefore, not easily cause deficiency disease.Choline is heat-resisting, in processing and gastronomical process
Loss seldom, under dry environment, has almost no change content of choline in some time storage food.Choline is lecithin
Sphingomyelins important component, lecithin is phosphatidyl choline, is widely present in animals and plants.The mankind and rat milk
A large amount of choline can be provided for newborn, it is ensured that the mechanism and multiple of fetus an d neonate acquisition choline.A small amount of phosphatide in film
Composition, including phosphatidyl 01 derivatives, Cholinphospholipide, especially phosphatidyl choline and sphingomyelin, are that can amplify
External signal or the bioactive molecule by generating inhibition second messenger abort signal process.Choline is also to regulating cell
Apoptosis has the irreplaceable important specific function of other methyl donors.Choline has affinity to fat, can promote rouge
Fat is transferred out by liver by blood with phospholipid form or is improved utilization of the fatty acid in liver itself, and prevents fat in liver
Abnormal accumulation in dirty.If fat, which accumulates in, fatty liver occurs without choline in liver, in morbid state.Clinically, using choline
Cirrhosis, hepatitis and other liver diseases are treated, are worked well.Choline and inositol (another vitamin B) are cooperated together to carry out
Utilization to fat and cholesterol；Choline is a small number of one of substances that can pass through " blood brain barrier ".This " barrier " protects brain
Portion is not influenced by the change of diet.But choline can enter brain cell by this " barrier ", manufacture the chemistry being memonic
Substance.Currently, the skin care effect research for choline is relatively fewer, choline is added in the cosmetics of part, but effect is still inadequate
It is ideal.
Vanillic acid is also known as vanillic acid, is widely present in nature, as vanilla beans, vanillic pod, Peru's balm,
It rests in peace and is found in many plants such as balm, Java perfume (or spice) crude oil and essential oil.In food industry, vanillic acid is mainly used for food
The food such as cruel cream, chocolate, milk, yogurt, peach, cocoa, pineapple are deployed in condiment.In cosmetics, perfume (or spice) can be used as
Essence prepares household chemicals, is to prepare the indispensable raw material of cosmetics, health product.In medicine, vanillic acid has certain resist
Bacterium ability has been used for treating in the formula of dermatosis treating medicine, is the indispensable raw material for synthesizing berberine on pharmaceutical synthesis；In addition,
Vanillic acid can also synthesize the drug L-methyldopa for the treatment of hypertension, and the treatment infection of the upper respiratory tract and prevention and treatment venereal disease bacterial strain are propagated
Methoxyamino pyridine and treatment heart disease papaverine etc..Meanwhile vanillic acid is also the production essential raw material of cumarin,
And there is good effect to treatment oral cavity is coarse etc..Currently, the market prospects that vanillic acid is used to production fragrance are extensive, demand
Very big, world's annual requirement is in 10kt or more, domestic demand about 1000t.Since the dissolubility of vanillic acid is weaker, there has been no will be fragrant
Skin care item of the oxalic acid as functional component.
In conclusion finding out a kind of comprehensive and skin care item with multi-efficiency of nutrition has important commercial value, if will
Choline and vanillic acid, which are added in skin care item, is expected to reach this target.
Summary of the invention
The technical problems to be solved by the present invention are: it is fragrant containing choline comprehensively and with multi-efficiency to provide a kind of nutrition
Skin care item of oxalates and preparation method thereof.
In order to solve the above-mentioned technical problem, a kind of the technical solution adopted by the present invention are as follows: shield containing choline vanillate
Skin product, the skin care item prepare raw material include choline vanillate, it is moisturizer, emollient, skin conditioning agent, emulsifier, molten
Agent, thickener, chelating agent and pH adjusting agent.
Further, the moisturizer includes 1,3-BDO, glycerol, glycerol caprylate, decoyl hydroximic acid, 1,2- penta 2
Alcohol and 1,2- hexylene glycol.
Further, the emollient includes caprylic/capric triglyceride, ethylhexyl palmitate, polydimethylsiloxanes
Alkane and dimethicone.
Further, the skin conditioning agent includes purslane extract.
Further, the thickener includes Acritamer 940 and transparent xanthan gum.
Further, the pH adjusting agent includes triethanolamine (Triethanolamine, TEA).
Further, the chelating agent includes disodium EDTA (Ethylenediaminetetraacetic
Acid disodium salt, EDTA-2Na).
Further, the emulsifier include tristerin, cetostearyl alcohol (and) cetearyl glucoside
(Montanov 68) and cetylstearyl alcohol (hexyldecyloctadecanol, C16/C18).
Further, the choline vanillate is 0.01~1% in the weight accounting prepared in raw material.
Further, it is described prepare raw material by choline vanillate, moisturizer, emollient, skin conditioning agent, emulsifier,
Solvent, thickener, chelating agent and pH adjusting agent composition, the weight accounting of the moisturizer are 10~15%；The skin condition
Agent is 0.1~1%；The weight accounting of the emollient is 15~20%；The weight accounting of the emulsifier is 3~8%；It is described
The weight accounting of thickener is 0.1~1%；The weight accounting of the chelating agent is 0.01~0.1%；The weight of the pH adjusting agent
Measuring accounting is 0.1~0.5%；The solvent is surplus.
Further, the skin care item are face cream.
The beneficial effects of the present invention are: " natural ion salt " the choline vanillate of the present invention program uses Green Chemistry
Synthetic technology, dissolubility enhance about 3 orders of magnitude than mono-acid vanilla solubility in acid, can be good at locking moisture of skin, avoid
Skin water loss and the dry skin caused.The thermal stability of this natural ion salt reaches 150 degrees Celsius, have both choline and
Vanillic acid double effects have inoxidizability and antiallergy, enhance wetting and protection to skin.Due to this natural ion salt
Based on cholinium ion, extracted from natural animal-plant, it therefore, can be as the important functional component in cosmetic formulations.Add
Added with choline vanillate skin care item in addition to skin care effect, also have both a variety of effects such as anti-oxidant, anti-inflammatory and antiallergy
Fruit.
The invention also includes the preparation method of the above-mentioned skin care item containing choline vanillate, will prepare raw material be divided into A, B,
After C and D phase, as follows prepared by step:
After S1, the processing that carries out disinfection to the first emulsion pot and the second emulsion pot, A phase raw material is added in the first emulsion pot,
75~90 DEG C are heated to, is stirred evenly；
S2, B phase raw material is added in the second emulsion pot, water, transparent xanthan gum and carbomer, stirring to dispersion is first added
It after uniformly, then puts into remaining B phase raw material and stirs evenly, be warming up to 75~85 DEG C, 20~40min of insulated and stirred；
S3, B phase raw material is added in A phase raw material, when being added, homogeneous is stirred, and is kept in adition process integral into stable cream
Shape；
S4,55~65 DEG C are cooled to, C phase raw material is added, stirs evenly；
S5,35~45 DEG C are cooled to, D phase raw material is added, 5~15min of stirring stops stirring, cooling to after being uniformly dispersed i.e.
Obtain the skin care item；Wherein, A phase raw material is oily phase raw material, and B phase raw material is Aqueous Phase Raw Material, and C phase raw material is pH adjusting agent, and D phase is former
Material is functional component.
Preferably, the solvent is water；The moisturizer includes glycerol, 1,3-BDO, 1,2- hexylene glycol, glycerol octanoic acid
Ester, decoyl hydroximic acid and 1,2- pentanediol；The emollient includes caprylic/capric triglyceride, ethylhexyl palmitate, poly- two
Methylsiloxane and dimethicone；The skin conditioning agent includes purslane extract；The emulsifier includes that stearic acid is sweet
Grease, Montanov 68 and C16/C18；The chelating agent includes EDTA-2Na；The pH adjusting agent includes TEA；The thickening
Agent includes carbomer and transparent xanthan gum；
A phase raw material includes tristerin, Montanov 68, C16/C18, caprylic/capric triglyceride, palmitinic acid
Ethylhexyl, dimethyl silicone polymer and dimethicone；B phase raw material include water, glycerol, EDTA-2Na, 1,3-BDO, thoroughly
Framingham raw rubber and carbomer；C phase raw material includes TEA；D phase raw material include 1,2- hexylene glycol, glycerol caprylate, decoyl hydroximic acid,
1,2- pentanediol, purslane extract and choline ellagic acid salt.
The beneficial effects of the present invention are: each component is dexterously classified, the material composition of the same category is in difference
At a temperature of add, by the present invention program sequence and temperature add each raw material component, can not only utmostly possess its activity at
Point, while the raw material being also more conducive in same phase preferably plays synergistic effect between each other.
Detailed description of the invention
Fig. 1 is the preparation flow schematic diagram of the embodiment of the present invention.
Specific embodiment
To explain the technical content, the achieved purpose and the effect of the present invention in detail, below in conjunction with embodiment and cooperate attached
Figure is explained.
The embodiment of the present invention 1 are as follows: a kind of Essence containing choline ellagic acid salt, by the component preparation of following parts by weight
: emulsifier: tristerin (A165), MONTANOV 68, C16/18；Emollient: caprylic/capric triglyceride
(GTCC), ethylhexyl palmitate (2EHP), dimethyl silicone polymer (DC200/100), dimethicone (KCC company, South Korea
The SF1000N-5CST of production)；Solvent: deionized water；Moisturizer: glycerol, 1,3-BDO, 1,2- hexylene glycol, A631 are (containing sweet
Oily caprylate, decoyl hydroximic acid and 1,2- pentanediol)；Thickener: transparent xanthan gum and Acritamer 940；PH adjusting agent: TEA (is used
In the pH value of product is adjusted to 5.0~5.6)；Chelating agent: EDTA-2Na；Skin conditioning agent: purslane extract；Choline is fragrant
Oxalates.
Purslane extract can anti-drying aging, increase skin comfort degree and remove free radical, improve skin comfort
Deng；By compounding for purslane extract, A165, MONTANOV68,2EHP etc. and choline vanillate, collaboration profit can be played
Skin moisturizing and other effects；Simultaneously, wherein choline vanillate has good anti-oxidant antiallergy effect as functional component.
It prepares raw material by above-mentioned and is divided into A, B, C and D phase raw material by such as the following table 1 rule:
The separate classification chart of 1 raw material of table
The above-mentioned preparation method containing choline vanillate face cream, as shown in Figure 1, comprising the following steps:
Step 1): with pure hot water washing and sterilizing emulsion pot；
Step 2): being added A phase emulsion pot for A group raw material, is heated to 80 DEG C and stirs evenly dispersion completely；
Step 3): separately taking one pot, and the dispersion of B phase emulsion pot is added in the deionized water of B phase, transparent xanthan gum and Ka Bo 940
Uniformly, remaining B phase raw material is added to stir evenly, stirring heat preservation 30 minutes after being warming up to 80 DEG C；
Step 4): being slowly added to A phase for B phase, and when being added, homogeneous is stirred, this process, which need to see whether to be formed, stablizes cream
Shape can continue to feed in this way；
Step 5): being cooled to 60 DEG C, and C phase is added, stirs evenly.
Step 6): continue stirring and be cooled to 40 DEG C, by the other raw material investment systems of D phase, and continue stir about 10 minutes
To being uniformly dispersed, stops stirring, cooling and then inspection and wait discharging；
Step 7): sealing storage vat after discharging, and moves between standing for use.
Step 8): semi-finished product dispense after quality inspection is qualified；
Step 9): packaging coding obtains finished product, is put in storage.
Wherein, the testing result in step 8) is as shown in table 2 below:
2 testing result table of table
The face cream has the effect of inhibiting melanin, repairs acne print, and face cream made from aforesaid operations is carried out compliance test result,
It is specific that test result is as follows:
1) inhibit the performance test of melanin
B16 cell in mouse melanin cell is carried out to face cream produced by the present invention and inhibits test, in 9cm diameter
With 1 × 10 in culture dish5The density of a/ml accesses B16 mouse melanin tumor cell, then in 37 DEG C, 5%CO2Under conditions of into
Supernatant is abandoned in row culture two days later, which (is added deionized water to dilute 10 times by the sample solution after adding filtration sterilization
Solution) 20ml, while the control group for not adding sample solution is set；Continue culture 3 days, abandons supernatant and carry out phosphate buffer
Trypsin solution (the matter of the trypsin solution of 0.5m1 is added in (Phosphate Buffered Saline, PBS) washing, every hole
Measuring percentage is that 0.2%) vitellophag 3min, every ware add 2ml maintaining liquid to terminate digestion, and piping and druming takes out 0.5ml after mixing and runs business into particular one
Born of the same parents count, remaining cell suspension is centrifuged 5min and is abandoned after supernatant with 2500r/min is added NaOH solution in precipitating, and heating makes
Melanin dissolution selects to survey absorbance value on the enzyme-linked immunosorbent assay instrument of 490nm wavelength, and calculating B16 cell inhibiting rate=
(1- (drug hole absorbance+drug hole cell density)+(control wells absorbance value+control wells cell density)) × 100%, specifically
Testing result is as shown in table 3 below:
3 melanin inhibitory effect experimental result of table
| Experimental group (repeats to test) | Inhibiting rate/% |
| 1 | 54.6 |
| 2 | 62.4 |
| 3 | 57.8 |
| 4 | 59.0 |
| 5 | 60.1 |
As can be seen from Table 3, the present invention program has good inhibiting effect to the synthesis of melanin, closes to melanin
At inhibiting rate about 59% or so.
2) light spot and the test of acne print repairing effect:
Selection has the male and female volunteer of acne print each 30, and the age at 22-40 years old, is randomly divided into 3 groups, to 3 groups of will
Hope person uses face cream of the present invention to take 6-10g to be applied to face before 10 points of every night respectively, pats to absorption, after 3 days
It counts light spot rate and statistics repairs situation after 7 days, as shown in table 4 below.
4 the embodiment of the present invention measure of merit result table of table
In upper table 4, light spot rate or repair rate are that have light spot effect or repairing effect region area to unite to after using
After meter with the ratio of the gross area of whole application area.
As can be seen from Table 4, face cream made from the present invention program has the problems such as spot, acne print of male and female good
Good repairing effect, and women is slightly better than to the whole reparation of male and light spot effect；And in three days light spot rate up to 90% with
On.
It is not strong that the face cream of the present invention program can effectively solve skin care item functionality in the prior art, easily causes skin allergy etc.
Problem, the salubrious moisturizing of the face cream of the present invention program, anti-aging have both anti-oxidant anti-inflammatory antianaphylactic effect.It is all in preparation process to connect
It touches cosmetics raw and auxiliary material, the equipment of semi-finished product, apparatus, pipeline to make of nontoxic, harmless, anti-anticorrosion material, inner wall light
Sliding nothing falls off；Production equipment carries out periodic maintenance, maintenance and cleaning, and production equipment will not introduce security risks substance.
Face cream is an important link in skin nursing, and face cream in the prior art is dazzling, and some face creams are to skin
Skin has sliminess, and the too strong and thick and heavy essence of fragrance causes skin not enough to moisten and salubrious；Some face creams, which contain, causes acne wind
The emulsifier of danger allows skin to become sensitive flesh；Face cream persistence also is not grown, and needs frequently to wipe face cream reagent；In addition, face
The assimilation effect of frost is also in the prior art one big problem, if face cream assimilation effect is not strong, the enhancing of skin oil soapy feeling, also
Allergic reaction may be caused.For this purpose, the present invention program propose natural ion salt face cream product development, have salubrious moisturizing,
Anti-aging has both anti-oxidant anti-inflammatory antianaphylactic effect.
The above description is only an embodiment of the present invention, is not intended to limit the scope of the invention, all to utilize this hair
Equivalents made by bright specification and accompanying drawing content are applied directly or indirectly in relevant technical field, similarly include
In scope of patent protection of the invention.
Claims (10)
1. a kind of skin care item containing choline vanillate, it is characterised in that: the raw material for preparing of the skin care item includes choline perfume
Oxalates, moisturizer, emollient, skin conditioning agent, emulsifier, solvent, thickener, chelating agent and pH adjusting agent.
2. the skin care item according to claim 1 containing choline vanillate, it is characterised in that: the moisturizer includes 1,
3- butanediol, glycerol, glycerol caprylate, decoyl hydroximic acid, 1,2- pentanediol and 1,2- hexylene glycol.
3. the skin care item according to claim 1 containing choline vanillate, it is characterised in that: the emollient includes pungent
Acid/Triglyceride DDD, ethylhexyl palmitate, dimethyl silicone polymer and dimethicone.
4. the skin care item according to claim 1 containing choline vanillate, it is characterised in that: the skin conditioning agent packet
Include purslane extract.
5. the skin care item according to claim 1 containing choline vanillate, it is characterised in that: the thickener includes card
Wave nurse 940 and transparent xanthan gum.
6. the skin care item according to claim 1 containing choline vanillate, it is characterised in that: the emulsifier includes hard
Glycerol, Montanov 68 and cetylstearyl alcohol.
7. the skin care item according to claim 1-6 containing choline vanillate, it is characterised in that: the choline
Vanillate is 0.01~1% in the weight accounting prepared in raw material.
8. the skin care item according to claim 7 containing choline vanillate, it is characterised in that: the raw material for preparing is by gallbladder
Alkali vanillate, moisturizer, emollient, skin conditioning agent, emulsifier, solvent, thickener, chelating agent and pH adjusting agent composition,
The weight accounting of the moisturizer is 10~15%；The skin conditioning agent is 0.1~1%；The weight accounting of the emollient
It is 15~20%；The weight accounting of the emulsifier is 3~8%；The weight accounting of the thickener is 0.1~1%；The chela
The weight accounting of mixture is 0.01~0.1%；The weight accounting of the pH adjusting agent is 0.1~0.5%；The solvent is remaining
Amount.
9. the skin care item according to claim 1-6 containing choline vanillate, it is characterised in that: the skin care
Product are face cream.
10. a kind of preparation method of the skin care item as described in claim 1 containing choline vanillate, it is characterised in that: will
It prepares after raw material is divided into A, B, C and D phase, as follows prepared by step:
After S1, the processing that carries out disinfection to the first emulsion pot and the second emulsion pot, A phase raw material, heating are added in the first emulsion pot
To 75~90 DEG C, stir evenly；
S2, B phase raw material is added in the second emulsion pot, is first added water, transparent xanthan gum and carbomer, stirring is to being uniformly dispersed
Afterwards, it then puts into remaining B phase raw material and stirs evenly, be warming up to 75~85 DEG C, 20~40min of insulated and stirred；
S3, B phase raw material is added in A phase raw material, when being added, homogeneous is stirred, and is kept in adition process integral into stablizing emulsus；
S4,55~65 DEG C are cooled to, C phase raw material is added, stirs evenly；
S5,35~45 DEG C are cooled to, D phase raw material is added, 5~15min of stirring stops stirring to after being uniformly dispersed, cools down up to institute
State skin care item；Wherein, A phase raw material is oily phase raw material, and B phase raw material is Aqueous Phase Raw Material, and C phase raw material is pH adjusting agent, and D phase raw material is
Functional component.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811592501.8A CN109528532A (en) | 2018-12-25 | 2018-12-25 | A kind of skin care item and preparation method thereof containing choline vanillate |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811592501.8A CN109528532A (en) | 2018-12-25 | 2018-12-25 | A kind of skin care item and preparation method thereof containing choline vanillate |
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| CN109528532A true CN109528532A (en) | 2019-03-29 |
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| CN201811592501.8A Pending CN109528532A (en) | 2018-12-25 | 2018-12-25 | A kind of skin care item and preparation method thereof containing choline vanillate |
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Application publication date: 20190329 |