CN109528611A - A kind of skin care item and preparation method thereof containing choline caffeiate - Google Patents
A kind of skin care item and preparation method thereof containing choline caffeiate Download PDFInfo
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- CN109528611A CN109528611A CN201811592548.4A CN201811592548A CN109528611A CN 109528611 A CN109528611 A CN 109528611A CN 201811592548 A CN201811592548 A CN 201811592548A CN 109528611 A CN109528611 A CN 109528611A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Abstract
The invention discloses a kind of skin care item and preparation method thereof containing choline caffeiate, the raw material for preparing of the skin care item includes: choline caffeiate, solvent, emulsifier, skin conditioning agent, emollient, moisturizer, pH adjusting agent, preservative, thickener；The raw material for preparing is divided into A, B, C and D phase, as follows prepared by step: A phase raw material S1, being added in the first emulsion pot, is heated to 75~90 DEG C, stirs evenly；S2, it B phase raw material is added in the second emulsion pot is uniformly dispersed, be warming up to 85~95 DEG C, after middling speed homogeneous 3-5min, 20~40min of insulated and stirred；S3, A phase raw material is added in B phase raw material, stirs while adding simultaneously homogeneous 3-8min；S4,55~65 DEG C are cooled to, C phase raw material is added, stirs evenly；S5,35~45 DEG C are cooled to, D phase raw material is added, stopped stirring after mixing evenly, cool down up to the skin care item.
Description
Technical field
The present invention relates to daily use chemicals technical fields, and in particular to a kind of skin care item containing choline caffeiate and its preparation side
Method.
Background technique
The eyes are the windows of the mind, and people first declines eye always, sees that the age sees eyes, the skin around eyes is than skin of face early ageing
8 years, therefore, for the promotion with people to the attention degree of appearance image, eye maintenance was also increasingly liked beauty by vast greatly
The attention of scholar.Due to the more delicate exquisiteness of eye part skin, eye-care cannot use and the identical skin care item of face, needs
Use the dedicated skin care item of eye.Eye cream is a kind of important product in eye skin care item, and eye cream has effects that saliva profit, in addition to
Outside the problem of black eye, eye pouch, crow's feet can be reduced, while also having effects that improve wrinkle, microgroove.According to function, eye
Frost is broadly divided into four major class: compact eye cream moistens eye cream, anti-aging eye cream and antiallergy eye cream.Compact eye cream is suitable for stemness
Skin properties are suitble to eye edema, and the skin for eye pouch occur uses.Compact eye cream can effectively soften, releive, loosening eye flesh
Skin promotes the metabolism of skin cell, tightens circumference of eyes skin, remolds the skin profile of consolidation.Moisten eye cream oiliness at
It is point higher, there is stronger moisture-keeping efficacy, the nourishing ingredient of water profit, the growth of the microgrooves such as effective pre- anti-wrinkle.Anti-aging eye cream
The free radical resisting ingredient contained can eliminate damage of the free radical to skin tissue, cell, slow down the aging aspects of eye skin,
It is suitble to summer and is used for a long time with the friend of computer；Eye skin is weak and sensitive, the variation of environment, temperature it is cold
Heat alternately, all easilys lead to the allergy of eye, the allergy of eye skin, shape of itching can be effectively prevented using antiallergy eye cream
Condition.Eye cream be all for most people it is required, in some special circumstances, eye cream should be applied early.As pole stemness
Skin person, pole dry skin are quite a lot in maiden.It is reported that at 18-24 years old neutral skin account for it is big mostly, but neutral skin
It is easy that partially dry or inclined oil condition is sometimes being presented.Secondly because season reason, many places are more drier and drier, especially nowadays
Global warm winter phenomenon, keep some time air humidity smaller and smaller, and the long-time of heating, air conditioner use, make face lack
Water, eye part skin stand in the breach.The person that is finally excess eye-using, modern job women be unable to do without text and computer mostly, add
A large amount of newpapers and periodicals, video optical disk dominate the leisurely and carefree time, and the extremely tired of eye muscle causes periocualr skin wrinkle to occur too early.One
As for must do within 20 years old moisturizing, eliminate tired homework, be suitble to a quality of selection pleasant, can effectively eye haustra -dsipelling and black eye
Eye cream；It must be done when 30 years old and maintain pleasant homework, be suitble to reinforce moisturizing, can reach and reinforce skin thickness and eliminate obvious black
The eye cream of the double effects of eyelet；Wrinkle reduction homework must be done within 40 years old, be suitble to rich in high concentration regeneration ingredient, with smoothing wrinkle,
The eye cream of consolidation relaxation skin；And 50 years old or more skin must do the brilliant homework that shines again, be suitble to using anti-wrinkle, compact, and have
There is the eye cream of modified.All kinds of eye skin care item have a single function in the prior art, it is difficult to meet the composite demand of user.
Choline is a kind of biostearin, while being also nutrient needed by human.It is the important component for constituting cell membrane,
It is also one of the raw material of human body synthesis glycine.It is separated first from pig's bile by Andreas Strecker within 1864,
It is synthesized chemically within 1866.The intracorporal choline of people, which has, greatly to be derived from food, and trimethylamine is broken down into large intestine.
Choline is a kind of strong organic base, is the constituent of lecithin, exists among sphingomyelin, is that body can be changed methyl
One source and the product for acting on synthesizing methyl, while being the precursor of acetylcholine again, it is also regarded as helping to mankind's brain
Development and memory.Human body can also synthesize choline, therefore, not easily cause deficiency disease.Choline is heat-resisting, in processing and gastronomical process
Loss seldom, under dry environment, has almost no change content of choline in some time storage food.Choline is lecithin
Sphingomyelins important component, lecithin is phosphatidyl choline, is widely present in animals and plants.The mankind and rat milk
A large amount of choline can be provided for newborn, it is ensured that the mechanism and multiple of fetus an d neonate acquisition choline.A small amount of phosphatide in film
Composition, including phosphatidyl 01 derivatives, Cholinphospholipide, especially phosphatidyl choline and sphingomyelin, are that can amplify
External signal or the bioactive molecule by generating inhibition second messenger abort signal process.Choline is also to regulating cell
Apoptosis has the irreplaceable important specific function of other methyl donors.Choline has affinity to fat, can promote rouge
Fat is transferred out by liver by blood with phospholipid form or is improved utilization of the fatty acid in liver itself, and prevents fat in liver
Abnormal accumulation in dirty.If fat, which accumulates in, fatty liver occurs without choline in liver, in morbid state.Clinically, using choline
Cirrhosis, hepatitis and other liver diseases are treated, are worked well.Choline and inositol (another vitamin B) are cooperated together to carry out
Utilization to fat and cholesterol；Choline is a small number of one of substances that can pass through " blood brain barrier ".This " barrier " protects brain
Portion is not influenced by the change of diet.But choline can enter brain cell by this " barrier ", manufacture the chemistry being memonic
Substance.Currently, the skin care effect research for choline is relatively fewer, choline is added in the cosmetics of part, but due to choline
Stability is weaker, causes effect still not ideal enough.
Caffeic acid is a kind of organic compound for belonging to hydroxycinnamic acid, while having two kinds of officials of phenolic hydroxyl group and acrylic acid
It can unity structure.Since caffeic acid is the key that in one of the main component of biosynthesis plant biomass and its residue lignin
Mesosome, therefore, it is widely present in various plants.Caffeic acid is common phenolic acid compound, has and promotes leucocyte
Effect, shrinkable solidification capilary improve coagulation factor function, the effect of increasing leukocyte and blood platelet.In vitro research and
Find that caffeic acid has a variety of potential pharmacological actions in animal model, by oxidation mechanism caffeic acid to people's HT-1080 fiber
The inhibiting effect to cancer cell multiplication in sarcoma cell line.Caffeic acid is in vitro and be all in vivo a kind of antioxidant.Coffee
Coffee acid also shows immunological regulation and anti-inflammatory activity, and caffeic acid can be such that aflatoxin yield reduces more than 95%, be better than other
Antioxidant.Research shows that triggering aspergillus flavus, which generates stress aoxidizing for Aflatoxin, to be hindered by caffeic acid.In the research of anticancer
In, high dose includes the growth that caffeinic combination antioxidant can then substantially reduce identical type rat colon tumour.Coffee
Acid can be used safely in cosmetics, have wide antibacterial and antiviral activity, can absorb ultraviolet light.Low concentration both has one
The effectiveness of straight melanin production, dosage is 0.5~2% in whitening type cosmetics.It can be used as the auxiliary agent of oxidisability hair fuel,
Be conducive to enhance the intensity of color.Since caffeinic dissolubility is bad, cause its additive effect bad.
It is typically more complicated in conclusion due to the eye skin problem of people, therefore, find out a kind of synthesis have it is more
The skin care item of kind effect are of great significance, and add choline and caffeic acid is expected to solve to realize above-mentioned purpose, however, the prior art
In not yet have been reported that.
Summary of the invention
The technical problems to be solved by the present invention are: providing a kind of have effects that wetting, anti-oxidant and anti-wrinkle contains gallbladder
The skin care item and preparation method thereof of alkali caffeiate.
In order to solve the above-mentioned technical problem, a kind of the technical solution adopted by the present invention are as follows: shield containing choline caffeiate
The raw material for preparing of skin product, the skin care item includes choline caffeiate, solvent, emulsifier, skin conditioning agent, emollient, moisturizing
Agent, thickener, preservative and pH adjusting agent.
Further, the emulsifier includes -20 methyl glucoside sesquistearate of polyethylene glycol
(Polyethylene Glycol-20 Methylglucoside Stearate, Glucate SSE-20), methyl glucoside
Sesquistearate (Methylglucoside stearate, Glucate SS) and cetylstearyl alcohol (C16/C18).
Further, the skin conditioning agent includes that vitamin E (Vitamin E, VE), aloe extract, purslane mention
Take object, peony extract and octyl polymethyl siloxane (BT-6034).
Further, the emollient include saualane, dimethyl silicone polymer (DC200/100), Spain's macadamia nut oil,
Hawaii macadamia nut oil (KUKUI oil) and rilanit special.
Further, the moisturizer includes glycerol, trehalose, methyl propanediol and Scleroglucan.
Further, the pH adjusting agent includes triethanolamine (Triethanolamine, TEA).
Further, the preservative includes methylparaben, propylben and compound preservative euxyl K220.
Further, the thickener includes carbomer.
Further, the choline caffeiate is 0.01~1% in the weight accounting prepared in raw material.
Further, the raw material for preparing is by choline caffeiate, solvent, emulsifier, skin conditioning agent, emollient, guarantor
Humectant, thickener, preservative and pH adjusting agent composition, the weight accounting of the emulsifier are 10~15%；The skin condition
Agent is 4~8%；The weight accounting of the emollient is 8~15%；The weight accounting of the moisturizer is 9~12%；The increasing
Thick dose of weight accounting is 0.1~1%；The weight accounting of the pH adjusting agent is 0.1~0.5%；The weight of the preservative
Accounting is 0.05~0.5%；The solvent is surplus.
Further, the skin care item are eye cream.
The beneficial effects of the present invention are: the present invention program provides a kind of skin care item added with natural biological ion salt
Formula and preparation method can effectively solve to be also easy to produce irritation or function to skin existing for the skin care item such as eye cream in background technique
The problems such as effect is insufficient；The skin care item such as eye cream in the prior art, because of ingredient and during preparing, functional component is different, Yi Zao
The problems such as pairs of skin.Not only ingredient is scientific and reasonable for skin care item containing natural biological ion salt, but also safe ready, " natural
Ion salt " choline caffeiate's salt uses green chemical synthesis technology, and dissolubility enhances about 3 numbers than mono-acid coffee solubility in acid
Magnitude can be good at locking moisture of skin, thus the effect of playing good moisturizing moisturizing.The heat of this natural ion salt is steady
It is qualitative to can reach 150 degrees Celsius, there is good anti-oxidant, antiallergy and bactericidal effect, enhance the wetting to skin and guarantor
Shield.Since this natural ion salt is based on choline and coffee acid ion, extracted from natural material, it therefore, can be as change
Important functional component in cosmetic formula.
The invention also includes the preparation methods of the above-mentioned skin care item containing choline caffeiate, and the raw material for preparing is divided into
A, B, C and D phase, A phase raw material are oiliness material, and B phase raw material is aqueous materials, and C phase raw material is pH adjusting agent, and D phase raw material is function
Imitate ingredient；
As follows prepared by step: after S1, the processing that carries out disinfection to the first emulsion pot and the second emulsion pot, in the first cream
Change and A phase raw material is added in pot, is heated to 75~90 DEG C, stirs evenly；
S2, it B phase raw material is added in the second emulsion pot is uniformly dispersed, be warming up to 85~95 DEG C, middling speed homogeneous 3-5min
Afterwards, 20~40min of insulated and stirred；
S3, A phase raw material is added in B phase raw material, stirs while adding simultaneously homogeneous 3-8min；
S4,55~65 DEG C are cooled to, C phase raw material is added, stirs evenly；
S5,35~45 DEG C are cooled to, D phase raw material is added, stopped stirring after mixing evenly, cool down up to the skin care item.
Preferably, the solvent is water；The emulsifier includes Glucate SSE-20, Glucate SS and C16/C18；
The skin conditioning agent includes VE, aloe extract, purslane extract, peony extract and octyl polymethyl siloxane；Institute
Stating emollient includes saualane, dimethyl silicone polymer, Spain's macadamia nut oil, Hawaii macadamia nut oil and rilanit special；It is described
Moisturizer includes glycerol, trehalose, methyl propanediol and Scleroglucan；The pH adjusting agent includes TEA；The preservative includes
Methylparaben, propylben and compound preservative euxyl K220；The thickener includes carbomer；A phase raw material includes
Glucate SSE-20, Glucate SS, C16/C18, octyl polymethyl siloxane, saualane, dimethyl silicone polymer, western class
Tooth macadamia nut oil, Macadamia nut oil, rilanit special and vitamin E；B phase raw material include water, glycerol, trehalose, methyl propanediol,
Scleroglucan, carbomer, methylparaben and propylben；C phase raw material includes TEA；The D phase raw material includes composite anti-corrosive
Agent euxyl K220, aloe extract, purslane extract, peony extract and choline caffeiate.
The beneficial effects of the present invention are: all contact cosmetics raw and auxiliary materials, the equipment of semi-finished product, use during the preparation process
Tool, pipeline are with the production of nontoxic, harmless, anti-anticorrosion material, and inner wall smooth is without falling off；Production equipment carries out periodic maintenance, protects
It supports and cleaning, production equipment will not introduce security risks substance.Each ingredient is dexterously classified, the raw material of the same category
Ingredient adds at different temperatures, adds each raw material component by the sequence and temperature of the present invention program, can not only utmostly protect
There is its active constituent, while the raw material being also more conducive in same phase preferably plays synergistic effect between each other.
Detailed description of the invention
Fig. 1 is the operational flowchart of the embodiment of the present invention.
Specific embodiment
To explain the technical content, the achieved purpose and the effect of the present invention in detail, below in conjunction with embodiment and cooperate attached
Figure is explained.
The embodiment of the present invention are as follows: a kind of eye cream containing choline caffeiate is made by the following raw material for preparing: solvent:
Deionized water；Emulsifier: Glucate SSE-20, Glucate SS (nonionic emulsifier and SSE-20 are used in mixed way) and ten
Six alkyl octadecanols (C16/C18)；Skin conditioning agent: vitamin E (Vitamin E, VE), aloe extract, purslane mention
Take object, peony extract and octyl polymethyl siloxane (BT-6034)；Emollient: saualane, dimethyl silicone polymer
(DC200/100), Spain's macadamia nut oil, Hawaii macadamia nut oil (KUKUI oil) and rilanit special；Moisturizer: glycerol, seaweed
Sugar, methyl propanediol and Scleroglucan；PH adjusting agent: TEA；Preservative: methylparaben, propylben and compound preservative
Euxyl K220 (main component methylisothiazolinone, ethylhexyl, glycerol, water)；Thickener: carbomer -941；Choline coffee
Coffee hydrochlorate；Wherein, Scleroglucan is not only used as moisturizer, but also plays the role of thickening as thickener simultaneously.
It prepares raw material by above-mentioned and is divided into A, B, C and D phase raw material by following table 1 rule:
The separate classification chart of 1 raw material of table
The preparation method of above-mentioned eye cream, as shown in Figure 1, comprising the following steps:
Step 1): with pure hot water washing and sterilizing emulsion pot；
Step 2): A phase raw material is added in emulsion pot, is heated to 85 DEG C, is stirred evenly；
Step 3): preparing another emulsion pot, and B phase raw material is added in emulsion pot and is uniformly dispersed, is stirred after being warming up to 90 DEG C
Mix heat preservation 30 minutes；
Step 4): being slowly added into B phase for A phase, stir while adding, and homogeneous 5 minutes；
Step 5): being cooled to 60 DEG C, and C phase raw material is added, stirs evenly.
Step 6): 40 DEG C are cooled to hereinafter, addition D phase raw material, stirs evenly, take the dish out of the pot after the assay was approved.
Step 7): sealing storage vat after discharging, and moves between standing for use.
Step 8): semi-finished product dispense after quality inspection is qualified；
Step 9): packaging coding obtains finished product, is put in storage.
Wherein, the testing result in step 8) is as shown in table 2 below:
2 testing result table of table
As can be seen from Table 2, eye cream made from the present invention program is safe and reliable.
Eye cream made from aforesaid operations is used for anti-wrinkle performance verification experiment (measurement of eyeprint shrinking percentage):
Test equipment:ChargeCoupling element (Charge-coupled Device, CCD) tests sensor, sine streak is thrown
Shadow instrument, skin rapid three dimensional imaging system PRIMOSlite.
Skin rapid three dimensional imaging system PRIMOS is since 2000 come out in dermatology, cosmetics research, medicine
Research field is widely applied.It is the digit optical three developed on the basis of a kind of fringe projection device based on digital micro-analysis
Tie up image analysis instrument.Fringe light with sine curve density when test is projected to skin or testee surface.Due to
Skin or testee apparent height it is uneven, fringe light will occur bending and deformation, and place in a special angle
CCD camera will record this variation simultaneously.It, can by testing the change in location of fringe light and the gray value of all picture points
To obtain entirely testing the digital three-dimensional image of skin surface or test object.Difference can be selected according to the difference of test assignment
Fringe light projected.
PRIMOS skin rapid three dimensional imaging system detection method is a kind of non-contacting test method of human body, this method
It has the advantages that
1, the testing time is short (260ms), is the shooting of skin real time video image；2, high-resolution and high-precision；3, light source
It is sufficiently strong, and light intensity can control.It can be adjusted when the skin surface of test different types, it is clearer convenient for obtaining
Image；4, testing efficiency is high, saves money, mass data can be acquired in the short time；5, whole system is controlled by PC machine, error rate
Low, data are analyzed quick and precisely；
6, possess a variety of test patterns: Overlay diplopia overlap test mode, Series Measurement series of tests
Mode etc. is compared using image obtains test result.
Test process:
Tested volunteer 20 (35-55 years old age) is randomly choosed, men and women is substantially fifty-fifty, and experiment position is eye circumference expression line
Region.Volunteer requires that any skin care item must not be used in experiment position on the day before on-test.Volunteer is allowed to test every time
Before stay in 25 DEG C of temperature or so, 10min in the environment that humidity is 50%.Take a small amount of (0.5-1g) test sample be uniformly applied to by
The experiment position for surveying volunteer, using sine stripe projection instrument exposure experiment position, and repeats five times, and tests sensor with CCD
The 3 d image data for acquiring experiment position handles data by skin rapid three dimensional imaging system PRIMOS lite and (takes five times
The average value of test) experimental result is obtained, as shown in table 3 below:
3 anti-wrinkle the performance test results table of table
From upper table 3, it is apparent that eye cream produced by the present invention is to eye anti-wrinkle significant effect.The present invention program is made
Eye cream can quick anti-wrinkle, it is not only good to the immediate effect of eye anti-wrinkle, and anti-wrinkle effect duration is long, anti-wrinkle is held
Continuous effect is good.In addition, in use to the non-stimulated fanout free region of skin, safety in utilization is good.
Each functional component of the present invention program formula is added with BT-6034, VE, aloe based on natural plant extracts
Extract, purslane extract and peony extract are as skin conditioning agent, wherein contain aloin and aloe rheum officinale in aloe
Polysaccharide compounds such as a variety of anthraquinone analog compounds such as element, diethylstilbestrol glucan, Glucomannan, Arabinogalactan and super
Superoxide dismutase, catalase etc. have good moisturizing, anti-inflammatory, antibacterial, antipruritic, antiallergy, softening skin, antioxygen
The multiple functions such as change；Purslane extract can anti-drying aging, increase skin comfort degree and remove free radical, improve skin relax
Suitable sense etc.；Contain Paeoniflorin isoreactivity ingredient in peony extract, it is inhibited to part pathogenic bacteria and fungi, together
When also have and inhibit elastoser, eliminate free radical, inhibit NO_x formation, promote a variety of function such as cathepsin active
Effect, in addition, peony extract also has good moisture-retaining capacity；The present invention program passes through aloe extract, purslane extract
With compounding for peony extract and choline caffeiate so that eye cream made from the present invention program is anti-ageing with good skin-active
While, it is also equipped with good antiallergy and moisture-keeping functions；Saualane, Spain's macadamia nut oil, Hawaii macadamia nut oil, hydrogenated castor
Oil etc. are compounded with choline caffeiate's, so that the present invention program has good moisturizing water lock effect.
Eye skin is the most thin skin of human body, while being the most frequent position of activity again, but also is pullled in makeup
The most place of skin number is particularly easy to grow wrinkle, and once grows and be difficult to eliminate, therefore, becoming of eye cream
Essential skin care item in cosmetic.Eye cream in the prior art is various in style, and ingredient is irregular.Some eye cream products are to eye
Portion's skin is irritant, is coated in massage on eyelid and just has burning feeling for a moment；Some eye cream heavy feelings are stronger, quality
Oil is crossed, the eye skin for being easy long fat granule is not suitable for；Eye cream also joined the ingredient of Chinese medicine, there is the taste of one eyedrops
Road allows consumer to hang back.The eye cream formulation product that the present invention develops, whole Effect raw materials come from natural product extraction,
Any artificial synthesized Effect raw material is not added, pure natural product develops, and has the multiple function such as wet, anti-oxidant, anti-wrinkle
Effect.
The above description is only an embodiment of the present invention, is not intended to limit the scope of the invention, all to utilize this hair
Equivalents made by bright specification and accompanying drawing content are applied directly or indirectly in relevant technical field, similarly include
In scope of patent protection of the invention.
Claims (10)
1. a kind of skin care item containing choline caffeiate, it is characterised in that: the raw material for preparing of the skin care item includes choline coffee
Coffee hydrochlorate, solvent, emulsifier, skin conditioning agent, emollient, moisturizer, thickener, preservative and pH adjusting agent.
2. the skin care item according to claim 1 containing choline caffeiate, it is characterised in that: the emulsifier includes
Glucate SSE-20, Glucate SS and cetylstearyl alcohol.
3. the skin care item according to claim 1 containing choline caffeiate, it is characterised in that: the skin conditioning agent packet
Include VE, aloe extract, purslane extract, peony extract and octyl polymethyl siloxane.
4. the skin care item according to claim 1 containing choline caffeiate, it is characterised in that: the emollient includes angle
Shark alkane, dimethyl silicone polymer, Spain's macadamia nut oil, Hawaii macadamia nut oil and rilanit special.
5. the skin care item according to claim 1 containing choline caffeiate, it is characterised in that: the moisturizer includes sweet
Oil, trehalose, methyl propanediol and Scleroglucan.
6. the skin care item according to claim 1-5 containing choline caffeiate, it is characterised in that: the choline
Caffeiate is 0.01~1% in the weight accounting prepared in raw material.
7. the skin care item according to claim 6 containing choline caffeiate, it is characterised in that: the raw material for preparing is by gallbladder
Alkali caffeiate, solvent, emulsifier, skin conditioning agent, emollient, moisturizer, thickener, preservative and pH adjusting agent composition,
The weight accounting of the emulsifier is 10~15%；The skin conditioning agent is 4~8%；The weight accounting of the emollient is 8
~15%；The weight accounting of the moisturizer is 9~12%；The weight accounting of the thickener is 0.1~1%；The pH tune
The weight accounting for saving agent is 0.1~0.5%；The weight accounting of the preservative is 0.05~0.5%；The solvent is surplus.
8. the skin care item according to claim 1-5 containing choline caffeiate, it is characterised in that: the skin care
Product are eye cream.
9. a kind of preparation method of the skin care item as described in claim 1 containing choline caffeiate, it is characterised in that: by institute
It states and prepares raw material and be divided into A, B, C and D phase, A phase raw material is oiliness material, and B phase raw material is aqueous materials, and C phase raw material is that pH is adjusted
Agent, D phase raw material are functional component；
As follows prepared by step: after S1, the processing that carries out disinfection to the first emulsion pot and the second emulsion pot, in the first emulsion pot
Middle addition A phase raw material, is heated to 75~90 DEG C, stirs evenly；
S2, it B phase raw material is added in the second emulsion pot is uniformly dispersed, be warming up to 85~95 DEG C, after middling speed homogeneous 3-5min, protect
20~40min of temperature stirring；
S3, A phase raw material is added in B phase raw material, stirs while adding simultaneously homogeneous 3-8min；
S4,55~65 DEG C are cooled to, C phase raw material is added, stirs evenly；
S5,35~45 DEG C are cooled to, D phase raw material is added, stopped stirring after mixing evenly, cool down up to the skin care item.
10. preparation method according to claim 9, it is characterised in that: the solvent is water；The emulsifier includes
Glucate SSE-20, Glucate SS and C16/C18；The skin conditioning agent includes VE, aloe extract, purslane extraction
Object, peony extract and octyl polymethyl siloxane；The emollient includes saualane, dimethyl silicone polymer, Spain's heavily fortified point
Fruit oil, Hawaii macadamia nut oil and rilanit special；The moisturizer includes glycerol, trehalose, methyl propanediol and Scleroglucan；
The pH adjusting agent includes TEA；The preservative includes methylparaben, propylben and compound preservative euxyl
K220；The thickener includes carbomer；
A phase raw material includes Glucate SSE-20, Glucate SS, C16/C18, octyl polymethyl siloxane, saualane, poly- two
Methylsiloxane, Spain's macadamia nut oil, Macadamia nut oil, rilanit special and vitamin E；B phase raw material includes water, glycerol, sea
Algae sugar, methyl propanediol, Scleroglucan, carbomer, methylparaben and propylben；C phase raw material includes TEA；The D phase
Raw material includes compound preservative euxyl K220, aloe extract, purslane extract, peony extract and choline caffeic acid
Salt.
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| CN201811592548.4A CN109528611A (en) | 2018-12-25 | 2018-12-25 | A kind of skin care item and preparation method thereof containing choline caffeiate |
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| CN201811592548.4A CN109528611A (en) | 2018-12-25 | 2018-12-25 | A kind of skin care item and preparation method thereof containing choline caffeiate |
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Application publication date: 20190329 |