CN109156476A - Unitary package sterilization powder and preparation method thereof - Google Patents
Unitary package sterilization powder and preparation method thereof Download PDFInfo
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- CN109156476A CN109156476A CN201811236525.XA CN201811236525A CN109156476A CN 109156476 A CN109156476 A CN 109156476A CN 201811236525 A CN201811236525 A CN 201811236525A CN 109156476 A CN109156476 A CN 109156476A
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
- A01N25/10—Macromolecular compounds
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/30—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A01N59/02—Sulfur; Selenium; Tellurium; Compounds thereof
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- Apparatus For Disinfection Or Sterilisation (AREA)
Abstract
The present invention relates to disinfection technology fields, especially unitary package sterilization powder, are made of the raw material of following weight percent: PEG is coated peroxide 30~45%；PEG coated active agent 15~30%；Surfactant 10~20%；Excipient 5~20%；And the sum of weight percent of each component is 100%, also discloses the preparation method of unitary package sterilization powder.The present invention has the advantages that making full use of PEG coating characteristics stable peroxide object and activating agent, so that each component does not react under solid form, the long advantage of transportation safety, storage time is realized；It makes full use of surfactant to accelerate dissolution of raw material in water, efficiently promotes release active oxygen, realize the good sterilization effect to the virus and bacteria in instrument and equipment；Adjustment different formulations ratio can be required according to different disinfections, meets disinfection and sterilization diversification requirement, and the preparation method of this disinfectant powder, reduces production cost and operation requires, and enriches the research of related fields.
Description
Technical field
The present invention relates to disinfection technology fields, especially unitary package sterilization powder and preparation method thereof.
Background technique
Disinfectant is a kind of disinfection and sterilization reagent that can effectively remove animals and plants, the spot of instrument and equipment, virus, bacterium,
At present the disinfectant that generally uses have solid disinfecting agent (chlorine dioxide, potassium permanganate), liquid-type (84 thimerosals, formalin,
Peracetic acid, hydrogen peroxide, hypochlorous acid etc.), gaseous decontaminant (chlorine).Wherein liquid disinfectant transport is inconvenient, when preservation
Between do not grow, be easy inactivation；Gaseous decontaminant toxicity is too big, and safety is low.
Under environmentally protective, safe and healthy consciousness, solid sterilizing powder is increasingly becoming the novel product of disinfectant, also more next
More welcomed by the people, routine disinfection powder has the packaged forms such as unitary, binary, polynary.Wherein unitary packaging uses simple, no
It is ideal disinfectant powder packaging with secondary compounding.But unitary packaging needs to carry out formulation agents reasonable selection and effective
Pre- protection, prevents raw material under solid-state form from directly reacting, loses sterilization effect.So to unitary disinfectant powder, especially pair
The unitary disinfectant powder of harmful, the high sterilization effect of animals and plants, instrument and equipment low toxicity has become research hotspot in recent years, not only has
Effect solves the disadvantage that liquid disinfectant transport is difficult, storage time is short, also solves the big deficiency of gaseous decontaminant toxicity.
Summary of the invention
The purpose of the present invention is to overcome the shortcomings of the existing technology, provides a kind of unitary package sterilization powder and its preparation side
Method realizes good processability and stability, has good sterilization effect to the virus and bacteria in instrument and equipment.
The purpose of the present invention is achieved through the following technical solutions: unitary package sterilization powder, by following weight percent
Raw material is made:
And the sum of weight percent of each component is 100%.
Further, the specification of PEG coating is selected from PEG-800, PEG-1000, PEG-1500, PEG-2000, PEG-4000
It is one or more.
Further, the oxide in the PEG coating peroxide is one of Potassium Monopersulfate, SODIUM PERCARBONATE
Or it is a variety of.
Further, the activating agent in the PEG coated active agent is tetraacetyl ethylene diamine.
Further, the surfactant is lauryl sodium sulfate, dodecyl benzyl dimethyl ammonium chloride, 14
Zephiran it is one or more.
Further, the excipient is one of anhydrous sodium sulfate, anhydrous sodium chloride, anhydrous magnesium sulfate or a variety of.
The preparation method of the unitary package sterilization powder, comprising the following steps:
S1, preparation PEG are coated peroxide；
S2, preparation PEG coated active agent；
PEG is coated peroxide, the agent of PEG coated active, surfactant, excipient allotment mixing by S3, raw material compounding
It uniformly clays into power up to disinfectant powder finished product.
Further, in step S1, preparation PEG is coated peroxide, specifically includes the following steps:
S11,90~110g PEG is dissolved in 900~1100ml dehydrated alcohol；
S12, it weighs in the above-mentioned solution of 580~620g peroxide addition, 2.5~3.5h is uniformly mixed；
S13, suction filtration are separated off extra polyethylene glycol coating solution, continue suction filtration and drain 2.5~3.5h, obtained solid 45
~55 DEG C are dried in vacuum overnight, and obtain PEG coating peroxide.
Further, in step S2, the agent of PEG coated active is prepared, specifically includes the following steps:
S21,90~110g polyethylene glycol is dissolved in 900~1100ml dehydrated alcohol；
S22, it weighs in the above-mentioned solution of 580~620g activating agent addition, 2.5~3.5h is uniformly mixed；
S23, suction filtration are separated off extra polyethylene glycol coating solution, continue suction filtration and drain 2.5~3.5h, obtained solid 45
~55 DEG C are dried in vacuum overnight, and obtain PEG coated active agent.
The invention has the following advantages that
1, PEG coating characteristics stable peroxide object and activating agent are made full use of, so that each component does not occur under solid form
The long advantage of transportation safety, storage time is realized in reaction；Surfactant is made full use of to accelerate dissolution of raw material in water, efficiently
Promote release active oxygen, realizes the good sterilization effect to the virus and bacteria in instrument and equipment.
2, adjustment different formulations ratio can be required according to different disinfections, meet disinfection and sterilization diversification requirement, it is this to disappear
The preparation method of malicious powder, reduces production cost and operation requires, and enriches the research of related fields.
Specific embodiment
Below with reference to embodiment, the present invention will be further described, but protection scope of the present invention is not limited to following institute
It states.
[embodiment 1]:
Unitary package sterilization powder, it is characterised in that: be made of the raw material of following weight percent:
Further, the specification of PEG coating is selected from PEG-800, PEG-1000, PEG-1500, PEG-2000, PEG-4000
It is one or more.
Further, the oxide in the PEG coating peroxide is SODIUM PERCARBONATE, i.e. PEG coated sodium percarbonate.
Further, the activating agent in the PEG coated active agent is tetraacetyl ethylene diamine, i.e. PEG is coated four acetyl second
Diamines.
Further, the surfactant is myristyl benzyl dimethyl ammonium chloride.
Further, the excipient is anhydrous sodium sulfate.
The preparation method of the unitary package sterilization powder, comprising the following steps:
S1, preparation PEG are coated peroxide；
S2, preparation PEG coated active agent；
PEG is coated peroxide, the agent of PEG coated active, surfactant, excipient allotment mixing by S3, raw material compounding
It uniformly clays into power up to disinfectant powder finished product.
Further, in step S1, preparation PEG is coated peroxide, specifically includes the following steps:
S11,90g PEG is dissolved in 900ml dehydrated alcohol；
S12, it weighs in the above-mentioned solution of 620g peroxide addition, 2.5h is uniformly mixed；
S13, suction filtration are separated off extra polyethylene glycol coating solution, continue suction filtration and drain 3.5h, 45 DEG C of obtained solid true
Sky is dried overnight, and obtains PEG coating peroxide.
Further, in step S2, the agent of PEG coated active is prepared, specifically includes the following steps:
S21,110g polyethylene glycol is dissolved in 1100ml dehydrated alcohol；
S22, it weighs in the above-mentioned solution of 580g activating agent addition, 3.5h is uniformly mixed；
S23, suction filtration are separated off extra polyethylene glycol coating solution, continue suction filtration and drain 3.5h, 45 DEG C of obtained solid true
Sky is dried overnight, and obtains PEG coated active agent.
Being detected had good sterilization effect to fungi, mycobacteria, spore, virus etc. at 30 minutes.It is examined after half a year
Survey still keeps sterilization effect.
[embodiment 2]:
Unitary package sterilization powder, it is characterised in that: be made of the raw material of following weight percent:
Further, the specification of PEG coating is selected from PEG-800, PEG-1000, PEG-1500, PEG-2000, PEG-4000
It is one or more.
Further, the oxide in the PEG coating peroxide is SODIUM PERCARBONATE, i.e. PEG coated sodium percarbonate.
Further, the activating agent in the PEG coated active agent is tetraacetyl ethylene diamine, i.e. PEG is coated four acetyl second
Diamines.
Further, the surfactant is dodecyl benzyl dimethyl ammonium chloride.
Further, the excipient is anhydrous sodium sulfate.
The preparation method of the unitary package sterilization powder, comprising the following steps:
S1, preparation PEG are coated peroxide；
S2, preparation PEG coated active agent；
PEG is coated peroxide, the agent of PEG coated active, surfactant, excipient allotment mixing by S3, raw material compounding
It uniformly clays into power up to disinfectant powder finished product.
Further, in step S1, preparation PEG is coated peroxide, specifically includes the following steps:
S11,90~110g PEG is dissolved in 900~1100ml dehydrated alcohol；
S12, it weighs in the above-mentioned solution of 580~620g peroxide addition, 2.5~3.5h is uniformly mixed；
S13, suction filtration are separated off extra polyethylene glycol coating solution, continue suction filtration and drain 2.5~3.5h, obtained solid 45
~55 DEG C are dried in vacuum overnight, and obtain PEG coating peroxide.
Further, in step S2, the agent of PEG coated active is prepared, specifically includes the following steps:
S21,90~110g polyethylene glycol is dissolved in 900~1100ml dehydrated alcohol；
S22, it weighs in the above-mentioned solution of 580~620g activating agent addition, 2.5~3.5h is uniformly mixed；
S23, suction filtration are separated off extra polyethylene glycol coating solution, continue suction filtration and drain 2.5~3.5h, obtained solid 45
~55 DEG C are dried in vacuum overnight, and obtain PEG coated active agent.
Being detected had good sterilization effect to fungi, mycobacteria, spore, virus etc. at 30 minutes.It is examined after half a year
Survey still keeps sterilization effect.
[embodiment 3]:
Unitary package sterilization powder, it is characterised in that: be made of the raw material of following weight percent:
Further, the specification of PEG coating is selected from PEG-800, PEG-1000, PEG-1500, PEG-2000, PEG-4000
It is one or more.
Further, the oxide in the PEG coating peroxide is Potassium Monopersulfate, i.e. PEG is coated single over cure
Potassium hydrogen phthalate.
Further, the activating agent in the PEG coated active agent is tetraacetyl ethylene diamine, i.e. PEG is coated four acetyl second
Diamines.
Further, the surfactant is myristyl benzyl dimethyl ammonium chloride.
Further, the excipient is anhydrous sodium sulfate.
The preparation method of the unitary package sterilization powder, comprising the following steps:
S1, preparation PEG are coated peroxide；
S2, preparation PEG coated active agent；
PEG is coated peroxide, the agent of PEG coated active, surfactant, excipient allotment mixing by S3, raw material compounding
It uniformly clays into power up to disinfectant powder finished product.
Further, in step S1, preparation PEG is coated peroxide, specifically includes the following steps:
S11,90~110g PEG is dissolved in 900~1100ml dehydrated alcohol；
S12, it weighs in the above-mentioned solution of 580~620g peroxide addition, 2.5~3.5h is uniformly mixed；
S13, suction filtration are separated off extra polyethylene glycol coating solution, continue suction filtration and drain 2.5~3.5h, obtained solid 45
~55 DEG C are dried in vacuum overnight, and obtain PEG coating peroxide.
Further, in step S2, the agent of PEG coated active is prepared, specifically includes the following steps:
S21,90~110g polyethylene glycol is dissolved in 900~1100ml dehydrated alcohol；
S22, it weighs in the above-mentioned solution of 580~620g activating agent addition, 2.5~3.5h is uniformly mixed；
S23, suction filtration are separated off extra polyethylene glycol coating solution, continue suction filtration and drain 2.5~3.5h, obtained solid 45
~55 DEG C are dried in vacuum overnight, and obtain PEG coated active agent.
Being detected had good sterilization effect to fungi, mycobacteria, spore, virus etc. at 30 minutes.It is examined after half a year
Survey still keeps sterilization effect.
[embodiment 4]:
Unitary package sterilization powder, it is characterised in that: be made of the raw material of following weight percent:
Further, the specification of PEG coating is selected from PEG-800, PEG-1000, PEG-1500, PEG-2000, PEG-4000
It is one or more.
Further, the oxide in the PEG coating peroxide is SODIUM PERCARBONATE, i.e. PEG coated sodium percarbonate.
Further, the activating agent in the PEG coated active agent is tetraacetyl ethylene diamine, i.e. PEG is coated four acetyl second
Diamines.
Further, the surfactant is myristyl benzyl dimethyl ammonium chloride.
Further, the excipient is anhydrous sodium sulfate.
The preparation method of the unitary package sterilization powder, comprising the following steps:
S1, preparation PEG are coated peroxide；
S2, preparation PEG coated active agent；
PEG is coated peroxide, the agent of PEG coated active, surfactant, excipient allotment mixing by S3, raw material compounding
It uniformly clays into power up to disinfectant powder finished product.
Further, in step S1, preparation PEG is coated peroxide, specifically includes the following steps:
S11,90~110g PEG is dissolved in 900~1100ml dehydrated alcohol；
S12, it weighs in the above-mentioned solution of 580~620g peroxide addition, 2.5~3.5h is uniformly mixed；
S13, suction filtration are separated off extra polyethylene glycol coating solution, continue suction filtration and drain 2.5~3.5h, obtained solid 45
~55 DEG C are dried in vacuum overnight, and obtain PEG coating peroxide.
Further, in step S2, the agent of PEG coated active is prepared, specifically includes the following steps:
S21,90~110g polyethylene glycol is dissolved in 900~1100ml dehydrated alcohol；
S22, it weighs in the above-mentioned solution of 580~620g activating agent addition, 2.5~3.5h is uniformly mixed；
S23, suction filtration are separated off extra polyethylene glycol coating solution, continue suction filtration and drain 2.5~3.5h, obtained solid 45
~55 DEG C are dried in vacuum overnight, and obtain PEG coated active agent.
Being detected had good sterilization effect to fungi, mycobacteria, spore, virus etc. at 30 minutes.It is examined after half a year
Survey still keeps sterilization effect.
[embodiment 5]:
Unitary package sterilization powder, it is characterised in that: be made of the raw material of following weight percent:
Further, the specification of PEG coating is selected from PEG-800, PEG-1000, PEG-1500, PEG-2000, PEG-4000
It is one or more.
Further, the oxide in the PEG coating peroxide is Potassium Monopersulfate, i.e. PEG is coated single over cure
Potassium hydrogen phthalate.
Further, the activating agent in the PEG coated active agent is tetraacetyl ethylene diamine, i.e. PEG is coated four acetyl second
Diamines.
Further, the surfactant is myristyl benzyl dimethyl ammonium chloride.
Further, the excipient is in anhydrous magnesium sulfate.
The preparation method of the unitary package sterilization powder, comprising the following steps:
S1, preparation PEG are coated peroxide；
S2, preparation PEG coated active agent；
PEG is coated peroxide, the agent of PEG coated active, surfactant, excipient allotment mixing by S3, raw material compounding
It uniformly clays into power up to disinfectant powder finished product.
Further, in step S1, preparation PEG is coated peroxide, specifically includes the following steps:
S11,90~110g PEG is dissolved in 900~1100ml dehydrated alcohol；
S12, it weighs in the above-mentioned solution of 580~620g peroxide addition, 2.5~3.5h is uniformly mixed；
S13, suction filtration are separated off extra polyethylene glycol coating solution, continue suction filtration and drain 2.5~3.5h, obtained solid 45
~55 DEG C are dried in vacuum overnight, and obtain PEG coating peroxide.
Further, in step S2, the agent of PEG coated active is prepared, specifically includes the following steps:
S21,90~110g polyethylene glycol is dissolved in 900~1100ml dehydrated alcohol；
S22, it weighs in the above-mentioned solution of 580~620g activating agent addition, 2.5~3.5h is uniformly mixed；
S23, suction filtration are separated off extra polyethylene glycol coating solution, continue suction filtration and drain 2.5~3.5h, obtained solid 45
~55 DEG C are dried in vacuum overnight, and obtain PEG coated active agent.
Being detected had good sterilization effect to fungi, mycobacteria, spore, virus etc. at 30 minutes.It is examined after half a year
Survey still keeps sterilization effect.
[embodiment 6]:
Unitary package sterilization powder, it is characterised in that: be made of the raw material of following weight percent:
Further, the specification of PEG coating is selected from PEG-800, PEG-1000, PEG-1500, PEG-2000, PEG-4000
It is one or more.
Further, the oxide in the PEG coating peroxide is Potassium Monopersulfate, i.e. PEG is coated single over cure
Potassium hydrogen phthalate.
Further, the activating agent in the PEG coated active agent is tetraacetyl ethylene diamine, i.e. PEG is coated four acetyl second
Diamines.
Further, the surfactant is myristyl benzyl dimethyl ammonium chloride.
Further, the excipient is anhydrous sodium sulfate.
The preparation method of the unitary package sterilization powder, comprising the following steps:
S1, preparation PEG are coated peroxide；
S2, preparation PEG coated active agent；
PEG is coated peroxide, the agent of PEG coated active, surfactant, excipient allotment mixing by S3, raw material compounding
It uniformly clays into power up to disinfectant powder finished product.
Further, in step S1, preparation PEG is coated peroxide, specifically includes the following steps:
S11,90~110g PEG is dissolved in 900~1100ml dehydrated alcohol；
S12, it weighs in the above-mentioned solution of 580~620g peroxide addition, 2.5~3.5h is uniformly mixed；
S13, suction filtration are separated off extra polyethylene glycol coating solution, continue suction filtration and drain 2.5~3.5h, obtained solid 45
~55 DEG C are dried in vacuum overnight, and obtain PEG coating peroxide.
Further, in step S2, the agent of PEG coated active is prepared, specifically includes the following steps:
S21,90~110g polyethylene glycol is dissolved in 900~1100ml dehydrated alcohol；
S22, it weighs in the above-mentioned solution of 580~620g activating agent addition, 2.5~3.5h is uniformly mixed；
S23, suction filtration are separated off extra polyethylene glycol coating solution, continue suction filtration and drain 2.5~3.5h, obtained solid 45
~55 DEG C are dried in vacuum overnight, and obtain PEG coated active agent.
Being detected had good sterilization effect to fungi, mycobacteria, spore, virus etc. at 30 minutes.It is examined after half a year
Survey still keeps sterilization effect.
[embodiment 7]:
Unitary package sterilization powder, it is characterised in that: be made of the raw material of following weight percent:
Further, the specification of PEG coating is selected from PEG-800, PEG-1000, PEG-1500, PEG-2000, PEG-4000
It is one or more.
Further, the oxide in the PEG coating peroxide is Potassium Monopersulfate, and as PEG is coated single mistake
Potassium acid sulfate.
Further, the activating agent in the PEG coated active agent is tetraacetyl ethylene diamine, and as PEG is coated four acetyl
Ethylenediamine.
Further, the surfactant is lauryl sodium sulfate.
Further, the excipient is in anhydrous sodium chloride.
The preparation method of the unitary package sterilization powder, comprising the following steps:
S1, preparation PEG are coated peroxide；
S2, preparation PEG coated active agent；
PEG is coated peroxide, the agent of PEG coated active, surfactant, excipient allotment mixing by S3, raw material compounding
It uniformly clays into power up to disinfectant powder finished product.
Further, in step S1, preparation PEG is coated peroxide, specifically includes the following steps:
S11,90~110g PEG is dissolved in 900~1100ml dehydrated alcohol；
S12, it weighs in the above-mentioned solution of 580~620g peroxide addition, 2.5~3.5h is uniformly mixed；
S13, suction filtration are separated off extra polyethylene glycol coating solution, continue suction filtration and drain 2.5~3.5h, obtained solid 45
~55 DEG C are dried in vacuum overnight, and obtain PEG coating peroxide.
Further, in step S2, the agent of PEG coated active is prepared, specifically includes the following steps:
S21,90~110g polyethylene glycol is dissolved in 900~1100ml dehydrated alcohol；
S22, it weighs in the above-mentioned solution of 580~620g activating agent addition, 2.5~3.5h is uniformly mixed；
S23, suction filtration are separated off extra polyethylene glycol coating solution, continue suction filtration and drain 2.5~3.5h, obtained solid 45
~55 DEG C are dried in vacuum overnight, and obtain PEG coated active agent.
Being detected had good sterilization effect to fungi, mycobacteria, spore, virus etc. at 30 minutes.It is examined after half a year
Survey still keeps sterilization effect.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding
And modification, the scope of the present invention is defined by the appended.
Claims (9)
1. unitary package sterilization powder, it is characterised in that: be made of the raw material of following weight percent:
And the sum of weight percent of each component is 100%.
2. unitary package sterilization powder according to claim 1, it is characterised in that: PEG coating specification be selected from PEG-800,
PEG-1000, PEG-1500, PEG-2000, PEG-4000's is one or more.
3. unitary package sterilization powder according to claim 1, it is characterised in that: the oxygen in the PEG coating peroxide
Compound is one of Potassium Monopersulfate, SODIUM PERCARBONATE or a variety of.
4. unitary package sterilization powder according to claim 1, it is characterised in that: the activity in the PEG coated active agent
Agent is tetraacetyl ethylene diamine.
5. unitary package sterilization powder according to claim 1, it is characterised in that: the surfactant is dodecyl sulphur
Sour sodium, dodecyl benzyl dimethyl ammonium chloride, myristyl benzyl dimethyl ammonium chloride it is one or more.
6. unitary package sterilization powder according to claim 1, it is characterised in that: the excipient is anhydrous sodium sulfate, nothing
One of water sodium chloride, anhydrous magnesium sulfate are a variety of.
7. the preparation method of the unitary package sterilization powder as described in claim 1~6 any one, it is characterised in that: including with
Lower step:
S1, preparation PEG are coated peroxide；
S2, preparation PEG coated active agent；
PEG coating peroxide, the agent of PEG coated active, surfactant, excipient are deployed and are uniformly mixed by S3, raw material compounding
It clays into power up to disinfectant powder finished product.
8. the preparation method of unitary package sterilization powder according to claim 7, it is characterised in that: in step S1, prepare PEG
It is coated peroxide, specifically includes the following steps:
S11,90~110g PEG is dissolved in 900~1100ml dehydrated alcohol；
S12, it weighs in the above-mentioned solution of 580~620g peroxide addition, 2.5~3.5h is uniformly mixed；
S13, suction filtration are separated off extra polyethylene glycol coating solution, continue suction filtration and drain 2.5~3.5h, obtained solid 45~55
It DEG C is dried in vacuum overnight, obtains PEG coating peroxide.
9. the preparation method of unitary package sterilization powder according to claim 8, it is characterised in that: in step S2, prepare PEG
Coated active agent, specifically includes the following steps:
S21,90~110g polyethylene glycol is dissolved in 900~1100ml dehydrated alcohol；
S22, it weighs in the above-mentioned solution of 580~620g activating agent addition, 2.5~3.5h is uniformly mixed；
S23, suction filtration are separated off extra polyethylene glycol coating solution, continue suction filtration and drain 2.5~3.5h, obtained solid 45~55
It DEG C is dried in vacuum overnight, obtains PEG coated active agent.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114145297A (en) * | 2021-12-21 | 2022-03-08 | 上海朗彤环境科技发展有限公司 | Unitary peracetic acid sterilizing powder and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114145297A (en) * | 2021-12-21 | 2022-03-08 | 上海朗彤环境科技发展有限公司 | Unitary peracetic acid sterilizing powder and preparation method thereof |
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Application publication date: 20190108 |