CN109123142A - A kind of pig feed additive and preparation method thereof improving immunity - Google Patents

A kind of pig feed additive and preparation method thereof improving immunity Download PDF

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Publication number
CN109123142A
CN109123142A CN201811018262.5A CN201811018262A CN109123142A CN 109123142 A CN109123142 A CN 109123142A CN 201811018262 A CN201811018262 A CN 201811018262A CN 109123142 A CN109123142 A CN 109123142A
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parts
feed additive
weight
pig feed
improving immunity
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吕桂英
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/14—Pretreatment of feeding-stuffs with enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/105—Aliphatic or alicyclic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/111—Aromatic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/174—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines

Abstract

The invention discloses a kind of pig feed additives for improving immunity, including below according to the raw material of parts by weight: 20-30 parts of Chinese medicine composition, 16-24 parts of plant extracts, 1-3 parts of multi-vitamins, 4-8 parts of SODLUM FULVATE, 0.5-2.5 parts of curcumin, the invention also discloses the preparation methods of the pig feed additive for improving immunity, feed prepared by the present invention contains Chinese medicine composition, emblic, there is between medicinal herbs good synergistic function in Longstamen Onion Bulb etc., the immunity of pig body can be effectively improved, facilitate the digestion of pig body, and letones rich in plant extracts, promote the blood circulation of pig body and metabolism, be conducive to the growth of pig body, contain SODLUM FULVATE, body immunity can be increased, adjust functions of intestines and stomach, contain curcumin, with antibacterial anti-inflammatory effect.

Description

A kind of pig feed additive and preparation method thereof improving immunity
Technical field
The present invention relates to technical field of animal husbandry, specifically a kind of pig feed additive for improving immunity and its preparation side Method.
Background technique
Feed addictive refers to a small amount of or micro substance added in Feed Manufacturing processing, use process, in feed Dosage is seldom but effect is significant.Feed addictive is the raw material that modern feed industry necessarily uses, to reinforcing basal feed nutrition Value improves breeding performonce fo animals, guarantees animal health, saves feed cost, and improvement livestock products quality etc. has apparent Effect.
Meanwhile in pig production, in order to accelerate the growth of pig, bigger economic benefit is obtained.Most raisers according to The method for so taking antibiotic and chemical synthesis class drug, can also make small intestine intestinal wall thinning, promote battalion while diseases prevention The absorption of substance is supported, to achieve the purpose that promote pig growth.But the problem of therefore bringing is also it is evident that not only antibiosis Element and the amount that uses of drug is increasing, effect worse and worse, antibiotic and medicament residue and problem of environmental pollution become day Benefit is prominent, therefore aiming at the problem that promoting pig growth, and it is crucial for developing the substitute of substitute antibiotics and drug as early as possible.
Summary of the invention
The purpose of the present invention is to provide a kind of pig feed additives and preparation method thereof for improving immunity, on solving State the problem of proposing in background technique.
To achieve the above object, the invention provides the following technical scheme:
A kind of pig feed additive improving immunity, including below according to the raw material of parts by weight: Chinese medicine composition 20-30 Part, 16-24 parts of plant extracts, 1-3 parts of multi-vitamins, 4-8 parts of SODLUM FULVATE, 0.5-2.5 parts of curcumin.
As a further solution of the present invention: including below according to the raw material of parts by weight: 22-28 parts of Chinese medicine composition is planted 18-22 parts of object extract, 1.5-2.5 parts of multi-vitamins, 5-7 parts of SODLUM FULVATE, 1-2 parts of curcumin.
As further scheme of the invention: including below according to the raw material of parts by weight: 25 parts of Chinese medicine composition, plant 20 parts of extract, 2 parts of multi-vitamins, 6 parts of SODLUM FULVATE, 1.5 parts of curcumin.
As further scheme of the invention: the Chinese medicine composition includes the following raw material according to parts by weight: from generation to generation Flower 1-5 parts, 3-5 parts of cassia seed extracting solution, 2-4 parts of emblic, 4-8 parts of sea-buckthorn, 3-6 parts of citron, 2-6 parts of galangal, fresh Rhizoma Phragmitis 2-3 parts, 3-7 parts of Longstamen Onion Bulb.
As the present invention further scheme: the cassia seed extracting solution the preparation method is as follows: depending on pine torch, clearly Wash, dry, be fried with slow fire heave, aromatic evolution when, taking-up cools down, crush, put into percolator, using 10-13 times The ethanol water of weight carries out seepage pressure effects, obtains percolate and seepage pressure effects residue, seepage pressure effects residue is added The ethanol water of 8-10 times of weight impregnates 2-3h, ultrasonic extraction 30-40min, and filtering, obtains ultrasonic extraction liquid and ultrasound mentions Residue is taken, ultrasonic extraction residue is added to the water of 4-6 times of weight, is put into autoclave, high pressure decocts 20-30min, it filters, High pressure extraction liquid and high pressure extraction residue are obtained, percolate, ultrasonic extraction liquid and high pressure extraction liquid are merged, is evaporated under reduced pressure Concentration is original volume 20% to get cassia seed extracting solution.
As the present invention further scheme: the plant extracts the preparation method is as follows: by motherwort and Sang Bai Skin 1:(2-3 in mass ratio) proportion crushes, 80 meshes are crossed, the powder both obtained, in mass ratio by powder and complex enzyme (80-100): 0.5 is uniformly mixed, and deionized water is added by solid-to-liquid ratio 1:(5-10), impregnates 12-24h, soaking temperature 30-40 DEG C, it is filtered after immersion, takes filter residue；Into filter residue press solid-to-liquid ratio 1:(6-8) be added 80-85% ethyl alcohol, refluxing extraction 3h, Vacuum filtration, takes filtrate, is concentrated, and is spray-dried, and crushes, sieves with 100 mesh sieve to get plant extracts, the complex enzyme is by β-Portugal Dextranase, pectase and zytase are mixed according to mass ratio for 1:2:3.
As the present invention further scheme: the multi-vitamins by vitamin A, vitamin B1, vitamin B2 and Vitamin E is mixed according to mass ratio for 1:1:2:1.
As further scheme of the invention: the preparation method of the pig feed additive for improving immunity, step It is as follows:
1) each raw material is weighed according to the ratio；
2) Chinese medicine composition is sufficiently crushed, is uniformly mixed, obtains herb powder；
3) plant extracts is pressed into solid-to-liquid ratio 1:(4-6) 80% ethyl alcohol is added, heating stirring is uniform, temperature 20-25 DEG C, mixing time 10-20min obtains plant extract solution；
4) plant extract solution of step 3) is sprayed to the herb powder of step 2), then be added multi-vitamins, SODLUM FULVATE and curcumin are thoroughly mixed uniformly, obtain mixture；
5) mixture for obtaining step 4) is dried, and drying temperature is 50-60 DEG C, obtains feed addictive.
Compared with prior art, the beneficial effects of the present invention are: feed prepared by the present invention contains Chinese medicine composition, emblic There is between medicinal herbs good synergistic function in son, Longstamen Onion Bulb etc., the immunity of pig body can be effectively improved, facilitate pig body Digestion, and letones rich in plant extracts promote the blood circulation of pig body and metabolism, containing yellow rotten Sour sodium can increase body immunity, containing curcumin, have antibacterial anti-inflammatory effect.
Specific embodiment
The technical solution of the patent is explained in further detail With reference to embodiment.
Embodiment 1
A kind of pig feed additive improving immunity, including below according to the raw material of parts by weight: 20 parts of Chinese medicine composition, 16 parts of plant extracts, 1 part of multi-vitamins, 4 parts of SODLUM FULVATE, 0.5 part of curcumin.
Wherein, the Chinese medicine composition includes the following raw material according to parts by weight: 1 part of bitter orange flower, cassia seed extracting solution 3 Part, 2 parts of emblic, 4 parts of sea-buckthorn, 3 parts of citron, 2 parts of galangal, 2 parts of fresh Rhizoma Phragmitis, 3 parts of Longstamen Onion Bulb.
The cassia seed extracting solution the preparation method is as follows: depend on pine torch, clean, dry, heaved with being fried with slow fire, had perfume (or spice) When gas escapes, taking-up is cooled down, and is crushed, and is put into percolator, is carried out seepage pressure effects using the ethanol water of 10 times of weight, is obtained Percolate and seepage pressure effects residue are obtained, seepage pressure effects residue is added to the ethanol water of 8 times of weight, impregnates 2h, ultrasound 30min is extracted, filtering obtains ultrasonic extraction liquid and ultrasonic extraction residue, and ultrasonic extraction residue is added to the water of 4 times of weight, throws Enter into autoclave, high pressure decocts 20min, and filtering obtains high pressure extraction liquid and high pressure extraction residue, by percolate, surpasses Sound extracting solution and high pressure extraction liquid merge, and concentration is evaporated under reduced pressure as the 20% of original volume to get cassia seed extracting solution.
Crushing the preparation method is as follows: motherwort and the root bark of white mulberry 1:2 in mass ratio are matched for the plant extracts, crosses 80 Mesh obtains the powder of the two, powder and complex enzyme 80:0.5 in mass ratio is uniformly mixed, and is added by solid-to-liquid ratio 1:5 Deionized water impregnates 12h, and soaking temperature is 30 DEG C, filters after immersion, takes filter residue；It is added into filter residue by solid-to-liquid ratio 1:6 80% ethyl alcohol, refluxing extraction 3h, vacuum filtration take filtrate, are concentrated, and are spray-dried, and crush, sieve with 100 mesh sieve and mention to get plant Object is taken, the complex enzyme is mixed by beta-glucan enzyme, pectase and zytase according to mass ratio for 1:2:3.
The multi-vitamins are 1:1:2:1 according to mass ratio by vitamin A, vitamin B1, vitamin B2 and vitamin E It mixes.
In the present embodiment, the preparation method of the pig feed additive for improving immunity, steps are as follows:
1) each raw material is weighed according to the ratio；
2) Chinese medicine composition is sufficiently crushed, is uniformly mixed, obtains herb powder；
3) plant extracts is added to 80% ethyl alcohol by solid-to-liquid ratio 1:4, heating stirring is uniform, and temperature is 20 DEG C, stirring Time is 10min, obtains plant extract solution；
4) plant extract solution of step 3) is sprayed to the herb powder of step 2), then be added multi-vitamins, SODLUM FULVATE and curcumin are thoroughly mixed uniformly, obtain mixture；
5) mixture for obtaining step 4) is dried, and drying temperature is 50 DEG C, obtains feed addictive.
Embodiment 2
A kind of pig feed additive improving immunity, including below according to the raw material of parts by weight: 22 parts of Chinese medicine composition, 18 parts of plant extracts, 1.5 parts of multi-vitamins, 5 parts of SODLUM FULVATE, 1 part of curcumin.
Wherein, the Chinese medicine composition includes the following raw material according to parts by weight: 1 part of bitter orange flower, cassia seed extracting solution 3 Part, 2 parts of emblic, 4 parts of sea-buckthorn, 3 parts of citron, 2 parts of galangal, 3 parts of fresh Rhizoma Phragmitis, 4 parts of Longstamen Onion Bulb.
The cassia seed extracting solution the preparation method is as follows: depend on pine torch, clean, dry, heaved with being fried with slow fire, had perfume (or spice) When gas escapes, taking-up is cooled down, and is crushed, and is put into percolator, is carried out seepage pressure effects using the ethanol water of 11 times of weight, is obtained Percolate and seepage pressure effects residue are obtained, seepage pressure effects residue is added to the ethanol water of 9 times of weight, impregnates 2.5h, is surpassed Sound extracts 35min, and filtering obtains ultrasonic extraction liquid and ultrasonic extraction residue, and ultrasonic extraction residue is added to the water of 5 times of weight, For investment into autoclave, high pressure decocts 22min, and filtering obtains high pressure extraction liquid and high pressure extraction residue, by percolate, Ultrasonic extraction liquid and high pressure extraction liquid merge, and concentration is evaporated under reduced pressure as the 20% of original volume to get cassia seed extracting solution.
The plant extracts crushes the preparation method is as follows: motherwort and the root bark of white mulberry 1:2.5 in mass ratio are matched, mistake 80 meshes obtain the powder of the two, powder and complex enzyme 85:0.5 in mass ratio are uniformly mixed, added by solid-to-liquid ratio 1:6 Enter deionized water, impregnate 16h, soaking temperature is 32 DEG C, filters after immersion, takes filter residue；Add into filter residue by solid-to-liquid ratio 1:7 Enter 80% ethyl alcohol, refluxing extraction 3h, vacuum filtration takes filtrate, is concentrated, and is spray-dried, and crushes, sieves with 100 mesh sieve to get plant Extract, the complex enzyme are mixed by beta-glucan enzyme, pectase and zytase according to mass ratio for 1:2:3.
The multi-vitamins are 1:1:2:1 according to mass ratio by vitamin A, vitamin B1, vitamin B2 and vitamin E It mixes.
In the present embodiment, the preparation method of the pig feed additive for improving immunity, steps are as follows:
1) each raw material is weighed according to the ratio；
2) Chinese medicine composition is sufficiently crushed, is uniformly mixed, obtains herb powder；
3) plant extracts is added to 80% ethyl alcohol by solid-to-liquid ratio 1:5, heating stirring is uniform, and temperature is 22 DEG C, stirring Time is 13min, obtains plant extract solution；
4) plant extract solution of step 3) is sprayed to the herb powder of step 2), then be added multi-vitamins, SODLUM FULVATE and curcumin are thoroughly mixed uniformly, obtain mixture；
5) mixture for obtaining step 4) is dried, and drying temperature is 52 DEG C, obtains feed addictive.
Embodiment 3
A kind of pig feed additive improving immunity, including below according to the raw material of parts by weight: 25 parts of Chinese medicine composition, 20 parts of plant extracts, 2 parts of multi-vitamins, 6 parts of SODLUM FULVATE, 1.5 parts of curcumin.
Wherein, the Chinese medicine composition includes the following raw material according to parts by weight: 1 part of bitter orange flower, cassia seed extracting solution 3 Part, 4 parts of emblic, 8 parts of sea-buckthorn, 5 parts of citron, 2 parts of galangal, 2 parts of fresh Rhizoma Phragmitis, 3 parts of Longstamen Onion Bulb.
The cassia seed extracting solution the preparation method is as follows: depend on pine torch, clean, dry, heaved with being fried with slow fire, had perfume (or spice) When gas escapes, taking-up is cooled down, and is crushed, and is put into percolator, is carried out seepage pressure effects using the ethanol water of 12 times of weight, is obtained Percolate and seepage pressure effects residue are obtained, seepage pressure effects residue is added to the ethanol water of 9 times of weight, impregnates 2.5h, is surpassed Sound extracts 35min, and filtering obtains ultrasonic extraction liquid and ultrasonic extraction residue, and ultrasonic extraction residue is added to the water of 5 times of weight, For investment into autoclave, high pressure decocts 25min, and filtering obtains high pressure extraction liquid and high pressure extraction residue, by percolate, Ultrasonic extraction liquid and high pressure extraction liquid merge, and concentration is evaporated under reduced pressure as the 20% of original volume to get cassia seed extracting solution.
The plant extracts the preparation method is as follows: by motherwort and the root bark of white mulberry 1:2 in mass ratio) proportion crush, mistake 80 meshes obtain the powder of the two, powder and complex enzyme 90:0.5 in mass ratio are uniformly mixed, added by solid-to-liquid ratio 1:7 Enter deionized water, impregnate 18h, soaking temperature is 35 DEG C, filters after immersion, takes filter residue；Add into filter residue by solid-to-liquid ratio 1:7 Enter 83% ethyl alcohol, refluxing extraction 3h, vacuum filtration takes filtrate, is concentrated, and is spray-dried, and crushes, sieves with 100 mesh sieve to get plant Extract, the complex enzyme are mixed by beta-glucan enzyme, pectase and zytase according to mass ratio for 1:2:3.
The multi-vitamins are 1:1:2:1 according to mass ratio by vitamin A, vitamin B1, vitamin B2 and vitamin E It mixes.
In the present embodiment, the preparation method of the pig feed additive for improving immunity, steps are as follows:
1) each raw material is weighed according to the ratio；
2) Chinese medicine composition is sufficiently crushed, is uniformly mixed, obtains herb powder；
3) plant extracts is added to 80% ethyl alcohol by solid-to-liquid ratio 1:5, heating stirring is uniform, and temperature is 23 DEG C, stirring Time is 15min, obtains plant extract solution；
4) plant extract solution of step 3) is sprayed to the herb powder of step 2), then be added multi-vitamins, SODLUM FULVATE and curcumin are thoroughly mixed uniformly, obtain mixture；
5) mixture for obtaining step 4) is dried, and drying temperature is 55 DEG C, obtains feed addictive.
Embodiment 4
A kind of pig feed additive improving immunity, including below according to the raw material of parts by weight: 28 parts of Chinese medicine composition, 22 parts of plant extracts, 2.5 parts of multi-vitamins, 7 parts of SODLUM FULVATE, 2 parts of curcumin.
Wherein, the Chinese medicine composition includes the following raw material according to parts by weight: 5 parts of bitter orange flower, cassia seed extracting solution 5 Part, 2 parts of emblic, 4 parts of sea-buckthorn, 3 parts of citron, 2 parts of galangal, 3 parts of fresh Rhizoma Phragmitis, 4 parts of Longstamen Onion Bulb.
The cassia seed extracting solution the preparation method is as follows: depend on pine torch, clean, dry, heaved with being fried with slow fire, had perfume (or spice) When gas escapes, taking-up is cooled down, and is crushed, and is put into percolator, is carried out seepage pressure effects using the ethanol water of 13 times of weight, is obtained Percolate and seepage pressure effects residue are obtained, seepage pressure effects residue is added to the ethanol water of 10 times of weight, impregnates 3h, ultrasound 40min is extracted, filtering obtains ultrasonic extraction liquid and ultrasonic extraction residue, and ultrasonic extraction residue is added to the water of 5 times of weight, throws Enter into autoclave, high pressure decocts 28min, and filtering obtains high pressure extraction liquid and high pressure extraction residue, by percolate, surpasses Sound extracting solution and high pressure extraction liquid merge, and concentration is evaporated under reduced pressure as the 20% of original volume to get cassia seed extracting solution.
Crushing the preparation method is as follows: motherwort and the root bark of white mulberry 1:3 in mass ratio are matched for the plant extracts, crosses 80 Mesh obtains the powder of the two, powder and complex enzyme 95:0.5 in mass ratio is uniformly mixed, and is added by solid-to-liquid ratio 1:8 Deionized water impregnates 20h, and soaking temperature is 40 DEG C, filters after immersion, takes filter residue；It is added into filter residue by solid-to-liquid ratio 1:7 85% ethyl alcohol, refluxing extraction 3h, vacuum filtration take filtrate, are concentrated, and are spray-dried, and crush, sieve with 100 mesh sieve and mention to get plant Object is taken, the complex enzyme is mixed by beta-glucan enzyme, pectase and zytase according to mass ratio for 1:2:3.
The multi-vitamins are 1:1:2:1 according to mass ratio by vitamin A, vitamin B1, vitamin B2 and vitamin E It mixes.
In the present embodiment, the preparation method of the pig feed additive for improving immunity, steps are as follows:
1) each raw material is weighed according to the ratio；
2) Chinese medicine composition is sufficiently crushed, is uniformly mixed, obtains herb powder；
3) plant extracts is added to 80% ethyl alcohol by solid-to-liquid ratio 1:6, heating stirring is uniform, and temperature is 25 DEG C, stirring Time is 20min, obtains plant extract solution；
4) plant extract solution of step 3) is sprayed to the herb powder of step 2), then be added multi-vitamins, SODLUM FULVATE and curcumin are thoroughly mixed uniformly, obtain mixture；
5) mixture for obtaining step 4) is dried, and drying temperature is 58 DEG C, obtains feed addictive.
Embodiment 5
A kind of pig feed additive improving immunity, including below according to the raw material of parts by weight: 30 parts of Chinese medicine composition, 24 parts of plant extracts, 3 parts of multi-vitamins, 8 parts of SODLUM FULVATE, 2.5 parts of curcumin.
Wherein, the Chinese medicine composition includes the following raw material according to parts by weight: 5 parts of bitter orange flower, cassia seed extracting solution 5 Part, 4 parts of emblic, 4 parts of sea-buckthorn, 3 parts of citron, 2 parts of galangal, 3 parts of fresh Rhizoma Phragmitis, 4 parts of Longstamen Onion Bulb.
The cassia seed extracting solution the preparation method is as follows: depend on pine torch, clean, dry, heaved with being fried with slow fire, had perfume (or spice) When gas escapes, taking-up is cooled down, and is crushed, and is put into percolator, is carried out seepage pressure effects using the ethanol water of 13 times of weight, is obtained Percolate and seepage pressure effects residue are obtained, seepage pressure effects residue is added to the ethanol water of 10 times of weight, impregnates 3h, ultrasound 40min is extracted, filtering obtains ultrasonic extraction liquid and ultrasonic extraction residue, and ultrasonic extraction residue is added to the water of 6 times of weight, throws Enter into autoclave, high pressure decocts 30min, and filtering obtains high pressure extraction liquid and high pressure extraction residue, by percolate, surpasses Sound extracting solution and high pressure extraction liquid merge, and concentration is evaporated under reduced pressure as the 20% of original volume to get cassia seed extracting solution.
The plant extracts the preparation method is as follows: by motherwort and the root bark of white mulberry 1:3 in mass ratio) proportion crush, mistake 80 meshes, the powder both obtained, in mass ratio 100) by powder and complex enzyme: 0.5 is uniformly mixed, by solid-to-liquid ratio 1:10 Deionized water is added, impregnates for 24 hours, soaking temperature is 40 DEG C, filters after immersion, takes filter residue；Solid-to-liquid ratio 1:8 is pressed into filter residue 85% ethyl alcohol, refluxing extraction 3h is added, vacuum filtration takes filtrate, is concentrated, and is spray-dried, and crushes, sieves with 100 mesh sieve to get plant Object extract, the complex enzyme are mixed by beta-glucan enzyme, pectase and zytase according to mass ratio for 1:2:3.
The multi-vitamins are 1:1:2:1 according to mass ratio by vitamin A, vitamin B1, vitamin B2 and vitamin E It mixes.
In the present embodiment, the preparation method of the pig feed additive for improving immunity, steps are as follows:
1) each raw material is weighed according to the ratio；
2) Chinese medicine composition is sufficiently crushed, is uniformly mixed, obtains herb powder；
3) plant extracts is added to 80% ethyl alcohol by solid-to-liquid ratio 1:6, heating stirring is uniform, and temperature is 25 DEG C, stirring Time is 20min, obtains plant extract solution；
4) plant extract solution of step 3) is sprayed to the herb powder of step 2), then be added multi-vitamins, SODLUM FULVATE and curcumin are thoroughly mixed uniformly, obtain mixture；
5) mixture for obtaining step 4) is dried, and drying temperature is 60 DEG C, obtains feed addictive.
Comparative example 1
Compared with Example 3, emblic is free of, other are same as Example 3.
Comparative example 2
Compared with Example 3, SODLUM FULVATE is free of, other are same as Example 3.
Comparative example 3
Compared with Example 3, emblic and SODLUM FULVATE are free of, other are same as Example 3.
Performance verification
Additive prepared by embodiment 3 and comparative example 1-3 is tested, to verify its influence to immunity.
Using cleaning grade Kunming mouse 100, half male and half female, weight (20 ± 3) g is grouped at random.Experimental group gives reality The additive of the preparation of example 3 is applied, control group 1-3 gives additive prepared by comparative example 1-3 respectively.Blank control group gives physiology Salt water.Using weight as standard, the administration standard of experimental group and control group 1-3 by 0.05g/kg, gastric infusion；Blank control group is given Give the physiological saline of peer accumulated amount, continuous gavage 10d.Influence by following metrics evaluation additive to mouse immunity. Its result is shown in Table 1-3 respectively.
(1) Immune Organs Index: de- neck puts to death mouse, takes mouse thymus and spleen, after weighing, calculates thymus index and spleen Dirty index.Thymus index=thymic weight/weight；Index and spleen index=spleen weight/weight.Test result is as shown in table 1.
1 Immune Organs Index test result table of table
Group Thymus gland organ index (mg/g) Spleen organ index (mg/g)
Embodiment 3 6.61 9.82
Comparative example 1 4.58 8.47
Comparative example 2 5.23 8.23
Comparative example 3 4.15 7.82
Blank control group 2.93 6.80
From result above as can be seen that compared with blank control group, the thymus gland internal organs of embodiment 3 and comparative example 1-3 refer to Several and spleen organ index is significantly increased, and the thymus gland organ index of embodiment 3 and spleen organ index are apparently higher than pair Ratio 1-3 illustrates that additive prepared by the present invention can significantly improve the thymus gland organ index and spleen organ index of mouse, and The change of thymus gland organ index and spleen organ index can reflect the state of body's immunity.Therefore, prepared by the present invention to add Add agent that can improve the immune function of mouse.
In addition, from the data comparison of embodiment 3 and comparative example 1-3 as can be seen that the present invention by be added emblic and SODLUM FULVATE, emblic and SODLUM FULVATE cooperate, and are conducive to improve additive to the reinforcing effect of immunity.
(2) immune function detects
The experiment of mouse carbonic clearance: it by 100mL/kg weight from 4 times of dilution of the injection of mouse tail vein clump of india ink, injects After prepared Chinese ink respectively in 2min, 10min from intraocular 20 μ L of corner of the eyes venous blood sampling, and be added to 0.1% Na2CO3In solution 2mL, 600nm wavelength densitometric value (OD), with 0.1% Na2CO3Solution cleans up index K as blank control, calculating.Test result As shown in table 2.
K=(lgOD1-lgOD2)/(t1-t2)
2 mouse carbonic clearance experimental result table of table
Group Clean up index
Embodiment 3 9.56
Comparative example 1 7.45
Comparative example 2 7.16
Comparative example 3 6.48
Blank control group 5.43
From result above as can be seen that compared with blank control group, embodiment 3 and comparative example 1-3 to clean up index equal It is significantly improved, and the index raising degree of cleaning up of embodiment 3 is apparently higher than comparative example 1-3, illustrates addition prepared by the present invention Agent can significantly improve the non-specific immune function of mouse.
In addition, from the data comparison of embodiment 3 and comparative example 1-3 as can be seen that the present invention by be added emblic and SODLUM FULVATE, emblic and SODLUM FULVATE cooperate, and are conducive to the enhancing effect for improving additive to non-specific immune function Fruit.
Feed prepared by the present invention contains Chinese medicine composition, has collaboration well in emblic, Longstamen Onion Bulb etc. between medicinal herbs Synergistic effect can effectively improve the immunity of pig body, facilitate the digestion of pig body, and rich in plant extracts Letones promote the blood circulation of pig body and metabolism that can increase body immunity containing SODLUM FULVATE, containing curcumin, With antibacterial anti-inflammatory effect.
It is obvious to a person skilled in the art that invention is not limited to the details of the above exemplary embodiments, Er Qie In the case where without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter From the point of view of which point, the present embodiments are to be considered as illustrative and not restrictive, and the scope of the present invention is by appended power Benefit requires rather than above description limits, it is intended that all by what is fallen within the meaning and scope of the equivalent elements of the claims Variation is included within the present invention.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art The other embodiments being understood that.

Claims (9)

1. a kind of pig feed additive for improving immunity, which is characterized in that including below according to the raw material of parts by weight: Chinese medicine group Close object 20-30 parts, 16-24 parts of plant extracts, 1-3 parts of multi-vitamins, 4-8 parts of SODLUM FULVATE, 0.5-2.5 parts of curcumin.
2. the pig feed additive according to claim 1 for improving immunity, which is characterized in that including below according to weight The raw material of part: 22-28 parts of Chinese medicine composition, 18-22 parts of plant extracts, 1.5-2.5 parts of multi-vitamins, SODLUM FULVATE 5-7 Part, 1-2 parts of curcumin.
3. the pig feed additive according to claim 2 for improving immunity, which is characterized in that including below according to weight The raw material of part: 25 parts of Chinese medicine composition, 20 parts of plant extracts, 2 parts of multi-vitamins, 6 parts of SODLUM FULVATE, 1.5 parts of curcumin.
4. the pig feed additive according to claim 1 for improving immunity, which is characterized in that the Chinese medicine composition packet Include the following raw material according to parts by weight: 1-5 parts of bitter orange flower, 3-5 parts of cassia seed extracting solution, 2-4 parts of emblic, 4-8 parts of sea-buckthorn, perfume 3-6 parts of rafter, 2-6 parts of galangal, 2-3 parts of fresh Rhizoma Phragmitis, 3-7 parts of Longstamen Onion Bulb.
5. the pig feed additive according to claim 4 for improving immunity, which is characterized in that the cassia seed extracting solution The preparation method is as follows: depend on pine torch, clean, dry, be fried with slow fire heave, aromatic evolution when, taking-up cools down, crush, Investment carries out seepage pressure effects into percolator, using the ethanol water of 10-13 times of weight, obtains percolate and diacolation mentions Residue is taken, seepage pressure effects residue is added to the ethanol water of 8-10 times of weight, impregnates 2-3h, ultrasonic extraction 30-40min, mistake Filter obtains ultrasonic extraction liquid and ultrasonic extraction residue, and ultrasonic extraction residue is added to the water of 4-6 times of weight, investment to autoclave In, high pressure decocts 20-30min, and filtering obtains high pressure extraction liquid and high pressure extraction residue, by percolate, ultrasonic extraction liquid Merge with high pressure extraction liquid, concentration is evaporated under reduced pressure as the 20% of original volume to get cassia seed extracting solution.
6. the pig feed additive according to claim 1 for improving immunity, which is characterized in that the plant extracts The preparation method is as follows: by motherwort and the root bark of white mulberry 1:(2-3 in mass ratio) proportion crushing, 80 meshes are crossed, the powdery of the two is obtained Object, powder and complex enzyme (80-100) in mass ratio: 0.5 are uniformly mixed, and deionized water is added by solid-to-liquid ratio 1:(5-10), 12-24h is impregnated, soaking temperature is 30-40 DEG C, filters after immersion, takes filter residue;Solid-to-liquid ratio 1:(6-8 is pressed into filter residue) plus Enter the ethyl alcohol of 80-85%, refluxing extraction 3h, vacuum filtration takes filtrate, is concentrated, and is spray-dried, and crushes, sieves with 100 mesh sieve to get plant Object extract, the complex enzyme are mixed by beta-glucan enzyme, pectase and zytase according to mass ratio for 1:2:3.
7. it is according to claim 1 improve immunity pig feed additive, which is characterized in that the multi-vitamins by Vitamin A, vitamin B1, vitamin B2 and vitamin E are mixed according to mass ratio for 1:1:2:1.
8. a kind of preparation method of the pig feed additive as claimed in claim 1 for improving immunity, feature exist In steps are as follows:
1) each raw material is weighed according to the ratio；
2) Chinese medicine composition is sufficiently crushed, is uniformly mixed, obtains herb powder；
3) plant extracts is pressed into solid-to-liquid ratio 1:(4-6) 80% ethyl alcohol is added, heating stirring is uniform, and temperature is 20-25 DEG C, stirs Mixing the time is 10-20min, obtains plant extract solution；
4) plant extract solution of step 3) is sprayed to the herb powder of step 2, multi-vitamins, yellow corruption are then added Sour sodium and curcumin are thoroughly mixed uniformly, obtain mixture；
5) mixture for obtaining step 4) is dried, and drying temperature is 50-60 DEG C, obtains feed addictive.
9. a kind of pig feed additive as claimed in claim 1 for improving immunity improves immunity of livestock in preparation Application in livestock products.
CN201811018262.5A 2018-09-03 2018-09-03 A kind of pig feed additive and preparation method thereof improving immunity Withdrawn CN109123142A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111066968A (en) * 2019-12-19 2020-04-28 金华市农业科学研究院 Additive premix for improving growth performance and carcass performance of Jinhua pork pigs and application thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111066968A (en) * 2019-12-19 2020-04-28 金华市农业科学研究院 Additive premix for improving growth performance and carcass performance of Jinhua pork pigs and application thereof

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Application publication date: 20190104