CN109072238B - 使用靶向结缔组织生长因子的rna复合物治疗特发性肺纤维化 - Google Patents
使用靶向结缔组织生长因子的rna复合物治疗特发性肺纤维化 Download PDFInfo
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- CN109072238B CN109072238B CN201780022913.5A CN201780022913A CN109072238B CN 109072238 B CN109072238 B CN 109072238B CN 201780022913 A CN201780022913 A CN 201780022913A CN 109072238 B CN109072238 B CN 109072238B
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662320944P | 2016-04-11 | 2016-04-11 | |
| US62/320,944 | 2016-04-11 | ||
| PCT/IB2017/000470 WO2017178883A2 (en) | 2016-04-11 | 2017-04-10 | Treatment of idiopathic pulmonary fibrosis using rna complexes that target connective tissue growth factor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109072238A CN109072238A (zh) | 2018-12-21 |
| CN109072238B true CN109072238B (zh) | 2022-05-24 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201780022913.5A Active CN109072238B (zh) | 2016-04-11 | 2017-04-10 | 使用靶向结缔组织生长因子的rna复合物治疗特发性肺纤维化 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10301628B2 (enExample) |
| EP (1) | EP3443093A4 (enExample) |
| JP (1) | JP7049262B2 (enExample) |
| KR (1) | KR102339886B1 (enExample) |
| CN (1) | CN109072238B (enExample) |
| CA (1) | CA3020487C (enExample) |
| WO (1) | WO2017178883A2 (enExample) |
Families Citing this family (15)
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| CA2818662C (en) | 2010-10-22 | 2021-07-06 | Sungkyunkwan University Foundation For Corporate Collaboration | Nucleic acid molecule inducing rna interference, and uses thereof |
| EP3514236A1 (en) * | 2012-05-22 | 2019-07-24 | Olix Pharmaceuticals, Inc. | Rna-interference-inducing nucleic acid molecule able to penetrate into cells, and use therefor |
| EP3377630A4 (en) | 2015-11-16 | 2020-01-01 | Olix Pharmaceuticals, Inc. | Treatment of age-related macular degeneration using rna complexes that target myd88 or tlr3 |
| CN108779463B (zh) | 2016-02-02 | 2022-05-24 | 奥利克斯医药有限公司 | 使用靶向IL4Rα、TRPA1或F2RL1的RNA复合物治疗特应性皮炎和哮喘 |
| WO2017134526A1 (en) | 2016-02-02 | 2017-08-10 | Olix Pharmaceuticals, Inc. | Treatment of angiogenesis-associated diseases using rna complexes that target angpt2 and pdgfb |
| WO2017178883A2 (en) * | 2016-04-11 | 2017-10-19 | Olix Pharmaceuticals, Inc. | Treatment of idiopathic pulmonary fibrosis using rna complexes that target connective tissue growth factor |
| KR101916652B1 (ko) | 2016-06-29 | 2018-11-08 | 올릭스 주식회사 | 작은 간섭 rna의 rna 간섭효과 증진용 화합물 및 이의 용도 |
| US11591600B2 (en) | 2017-02-10 | 2023-02-28 | OliX Pharmaceuticals. Inc. | Long double-stranded RNA for RNA interference |
| WO2020027640A1 (ko) * | 2018-07-31 | 2020-02-06 | 주식회사 레모넥스 | Ctgf 발현 억제용 조성물 |
| KR20200014684A (ko) * | 2018-07-31 | 2020-02-11 | 주식회사 레모넥스 | Ctgf 발현 억제용 조성물 |
| CN109402127B (zh) * | 2018-09-29 | 2021-12-10 | 复旦大学附属眼耳鼻喉科医院 | 一组与结缔组织生长因子特异性结合的高亲和力核酸适配体及其应用 |
| WO2020122534A1 (ko) * | 2018-12-10 | 2020-06-18 | 올릭스 주식회사 | Snai1의 발현을 억제하는 비대칭 sirna |
| KR102161041B1 (ko) | 2018-12-13 | 2020-10-05 | 영남대학교 산학협력단 | 살리노마이신을 유효성분으로 함유하는 세포노화 관련 질환 예방 또는 치료용 조성물 |
| CN111378655B (zh) * | 2018-12-28 | 2024-03-19 | 苏州瑞博生物技术股份有限公司 | 抑制CTGF基因表达的siRNA、含有该siRNA的药物组合物及其用途 |
| US20240093188A1 (en) * | 2020-05-26 | 2024-03-21 | Olix Pharmaceuticals, Inc. | RNAi AGENT TARGETING MYD88 AND USE THEREOF |
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| US10301628B2 (en) | 2019-05-28 |
| JP2019513384A (ja) | 2019-05-30 |
| KR20180128423A (ko) | 2018-12-03 |
| US20190367925A1 (en) | 2019-12-05 |
| WO2017178883A8 (en) | 2018-12-06 |
| CN109072238A (zh) | 2018-12-21 |
| WO2017178883A2 (en) | 2017-10-19 |
| US20170298358A1 (en) | 2017-10-19 |
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| EP3443093A2 (en) | 2019-02-20 |
| CA3020487A1 (en) | 2017-10-19 |
| EP3443093A4 (en) | 2020-01-01 |
| JP7049262B2 (ja) | 2022-04-06 |
| US10829761B2 (en) | 2020-11-10 |
| KR102339886B1 (ko) | 2021-12-17 |
| WO2017178883A3 (en) | 2018-08-23 |
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