CN109071430A - 环肽的片段合成 - Google Patents

环肽的片段合成 Download PDF

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Publication number
CN109071430A
CN109071430A CN201680078545.1A CN201680078545A CN109071430A CN 109071430 A CN109071430 A CN 109071430A CN 201680078545 A CN201680078545 A CN 201680078545A CN 109071430 A CN109071430 A CN 109071430A
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China
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aryl
lower alkyl
compound
independently selected
amino acid
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Pending
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CN201680078545.1A
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Chinese (zh)
Inventor
曼努埃尔·佩雷斯·巴斯克斯
M·曼苏尔·穆尔希德
珍妮弗·L·希基
马克-安德·普帕特
杨高强
詹姆斯·吉尔拉德
阿达姆·保罗·卡法尔
安德鲁·L·拉夫顿
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University of Montreal
Zealand Pharma AS
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University of Montreal
Encycle Therapeutics Inc
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Publication of CN109071430A publication Critical patent/CN109071430A/zh
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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CN201680078545.1A 2015-11-11 2016-11-14 环肽的片段合成 Pending CN109071430A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562254003P 2015-11-11 2015-11-11
US62/254,003 2015-11-11
PCT/CA2016/000275 WO2017079821A1 (en) 2015-11-11 2016-11-14 Fragment synthesis of cyclic peptides

Publications (1)

Publication Number Publication Date
CN109071430A true CN109071430A (zh) 2018-12-21

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Family Applications (2)

Application Number Title Priority Date Filing Date
CN201680078545.1A Pending CN109071430A (zh) 2015-11-11 2016-11-14 环肽的片段合成
CN201680079148.6A Active CN109071602B (zh) 2015-11-11 2016-11-14 靶向α4β7整联蛋白的环肽

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201680079148.6A Active CN109071602B (zh) 2015-11-11 2016-11-14 靶向α4β7整联蛋白的环肽

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US (4) US11072616B2 (enExample)
EP (2) EP3377471A4 (enExample)
JP (1) JP6961586B2 (enExample)
KR (1) KR102867019B1 (enExample)
CN (2) CN109071430A (enExample)
AU (1) AU2016353547B9 (enExample)
CA (2) CA3004641A1 (enExample)
WO (2) WO2017079821A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3377471A4 (en) 2015-11-11 2019-11-20 Encycle Therapeutics, Inc. FRAGMENT SYNTHESIS OF CYCLIC PEPTIDES
EP3939989A1 (en) 2016-11-11 2022-01-19 Zealand Pharma A/S Cyclic peptides multimers targeting alpha 4beta 7 integrin
KR20200015540A (ko) * 2017-05-10 2020-02-12 인사이클 세라퓨틱스, 인코포레이티드 α4β7 인테그린을 타겟팅하는 호모데틱 사이클릭 펩타이드
CN110551178B (zh) * 2018-06-01 2020-07-21 深圳翰宇药业股份有限公司 一种含脯氨酸的首尾环肽合成方法
JP7670618B2 (ja) * 2019-03-14 2025-04-30 エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト 環状ペプチド抗生物質
JP2021106565A (ja) * 2019-12-27 2021-07-29 国立大学法人 東京大学 ライブラリーの製造方法、環状ペプチド、ＦＸＩＩａ結合剤、及びＩＦＮＧＲ１結合剤
EP4101929A4 (en) * 2019-12-27 2024-05-22 The University of Tokyo BANK CONSTRUCTION METHOD, CYCLIC PEPTIDE, FXIIA BINDER AND IFNGR1 BINDER
TWI908822B (zh) 2020-06-29 2025-12-21 丹麥商西蘭製藥公司 化合物
KR20240116921A (ko) 2021-12-20 2024-07-30 질랜드 파마 에이/에스 화합물
WO2026018016A1 (en) * 2024-07-19 2026-01-22 C4X Discovery Limited Therapeutic compounds
WO2026018017A1 (en) * 2024-07-19 2026-01-22 C4X Discovery Limited Therapeutic compounds

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DE3219113A1 (de) * 1982-05-21 1983-11-24 Bayer Ag, 5090 Leverkusen Verwendung von n-substituierten 2,3-diaminocarbonsaeuren in arzneimitteln und ihre herstellung
US5296604A (en) * 1992-05-15 1994-03-22 Miles Inc. Proline derivatives and compositions for their use as inhibitors of HIV protease
WO2009141687A1 (en) * 2008-05-22 2009-11-26 Centre National De La Recherche Scientifique (Cnrs) New optically pure compounds for improved therapeutic efficiency
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