CN109043030A - A kind of health-care tea for fat-reducing liver-fortifying and preparation method thereof - Google Patents

A kind of health-care tea for fat-reducing liver-fortifying and preparation method thereof Download PDF

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CN109043030A
CN109043030A CN201810885243.6A CN201810885243A CN109043030A CN 109043030 A CN109043030 A CN 109043030A CN 201810885243 A CN201810885243 A CN 201810885243A CN 109043030 A CN109043030 A CN 109043030A
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parts
fat
health
fortifying
care tea
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王启兰
党军
陶燕铎
王蒲
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Northwest Institute of Plateau Biology of CAS
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    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
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    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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Abstract

The invention discloses a kind of health-care tea for fat-reducing liver-fortifying, the raw material of the health-care tea for fat-reducing liver-fortifying is made of green orchid, yellow mushroom, Swertia mussotii, black fungus, hawthorn, fructus lycii, jujube, STEVIA REBAUDIANA, the weight of the raw material are as follows: green 10~20 parts blue, 10~30 parts of yellow mushroom, 3~7 parts of Swertia mussotii, 15~35 parts of black fungus, 5~15 parts of hawthorn, 5~15 parts of fructus lycii, 5~15 parts of jujube, 2~8 parts of STEVIA REBAUDIANA.Health protection tea of the present invention can preferably reach the effect of lowering fat and protecting liver, be refined by the Natural Food medicinal material of dual-purpose of drug and food, be free of any chemical synthesis substance, naturally environmentally friendly, long-term use can promote metabolism, enhance immunity of organisms, and it is low in cost, preparation process is simple, reproducible.

Description

A kind of health-care tea for fat-reducing liver-fortifying and preparation method thereof
Technical field
The present invention relates to contain the health care product from plant component, in particular to a kind of health-care tea for fat-reducing liver-fortifying and its system Preparation Method.
Background technique
Fatty liver be with hepatic cell fattydegeneration and fat aggregation it is excessive based on clinical pathology syndrome, have become existing The common disease of generation life, is not with the passing of time cured, the incidence of liver fibrosis is up to 25%, and has 1.5% ~ 8.0% patient that can develop as liver Hardening, finally results in liver failure and dead.
With the development of society, people's living standard is gradually increased, diet is more diversified, the selection of dietary structure The fat regimen amount of more diversification, people also increased, and then blood lipid level is caused to also improve much.Currently, high blood Pressure and hyperlipidemia have become the principal disease for threatening middle-aged and the old's health.Researches show that: hyperlipidemia, hyperglycemia, hypertension, fertilizer Fat, waistline increase is the risk factor of fatty liver.
Labiatae dragonhead is distributed mainly on Asia temperate zone there are about 60 kinds, chemical component mainly include volatile oil, Flavones and flavonoid glycoside, phytosterol and triterpenes, organic acid and esters etc., have anti anoxia, anti-oxidant, protection is cardiovascular, A variety of pharmacological activity such as antitumor, removing free radical, antiviral and liver protection.(the chemistry of Liu Jianying, Liu Yu plum dragonhead Ingredient and Advance on Pharmacological Activities Food Science, 2012,33 (13): 314-319).
Armillaria luteo-virens also known as yellowish green frizzle mushroom, yellow mushroom etc., are under the jurisdiction of mycota, Basidiomycota, agaric subphylum, agaric Guiding principle, Agaricales, Agaricaceae, frizzle mushroom category.Armillaria luteo-virens are a kind of rare wild edible and medical fungi, nutriture value with higher Value, also detects such as vitamin B1, vitamin B2, vitamin C rich in 18 kinds of amino acid containing type vitamin abundant, Middle content is higher for 8 kinds of amino acid necessary to human body.Armillaria luteo-virens it is reported that have resisiting influenza virus, prevention and treatment neuritis with And the effect of athlete's foot, while can also promote upgrowth and development of children, it is anti-oxidant, antitumor the effects of.(horse beautiful jade Armillaria luteo-virens Chemical component and bioactivity research [D] University Of Tianjin, 2015.).
Swertia mussotii is the rarity in Chinese nation's medicine, is one of Tibetan medicine eight delicacies in Qinghai-Tibet Platean.It is hidden in traditional Tibetanmedicine Oriental wormwood refers mainly to Swertia, is that one of Gentianaceae belongs to greatly, including 11 group 16 is 154 kinds, is belonged between north temperate zone and the south temperate zone Disconnected distribution, most Species distributings are in Asia.China has 79 kinds, can hyoscine plant have mussot swertia herb, embrace stem river deer tooth More than dish, Qilian river deer tooth, Halenia elliptica D. Don 40.The involatile constituent contained in Swertia mussotii mainly has triterpenes, ketone, mango The ingredients such as glycosides, gentiamarin, Swertiamarin, polysaccharide.Research shows that: Swertia mussotii have good protection liver effect, resist it is micro- Biology and helminth effect, anti-cancer and cancer-preventing effect.Swertia mussotii can also adjust sexual function or influence endocrine function, improve skin function It can, promote hair growth, red bar of disease for the treatment of, treatment acute nephritis, acute cystitis, chronic cholecystitis with muddy stone, son (Fan Shuqing, Zhou Song, Lu Zhiqiang, Zhang Ximin Swertia mussotii chemical component and Advance on Pharmacological Activities [J] are modern for cervical erosion etc. Combination of Chinese tradiational and Western medicine magazine, 2012,21 (02): 227-228.).
Black fungus integration of drinking and medicinal herbs both can satisfy demand of the people to cuisines, be used for a long time, and can prevent and mitigate high blood Pressure and hyperlipidemia etc. " rich people's disease ".Contain polysaccharide, adenosine substance, ergosterol, lecithin, cephalin and sheath phosphorus in black fungus Rouge also contains vitamin A, vitamin D2And vitamin K etc..Research shows that: black fungus has lipid-loweringing, antithrombotic, anti-radiation, anti- Mutation, anti-oxidant, anti-aging, it is hypoglycemic, antitumor the effects of (Liu Yajing, Yuan Yanqiang, Liu Xiuhe, Liu can the black fungus nutrition of spring Health care progress [J] Chinese food and nutrition, 2010 (10): 66-69.).
Hawthorn alias red fruit, Chinese bush cherry, green pears, Fructus Crataegi are the dry fruit of rosaceous plant large-fruited Chinese hawthorn or hawthorn, taste It is sour, sweet, tepor, returns spleen, stomach, Liver Channel.Hawthorn is medicinal and edible plant, contains flavonoids, flavane and its polymerization species, triterpenes With a variety of chemical components such as organic acid, mainly have adjust blood lipid, liver protection, decompression, aid digestion, heart tonifying, it is anti-oxidant, antitumor, The effects of antibacterial (building ground force, Luo Jiexia, the chemical component and pharmacological research of high cloud hawthorn summarize [J] China medicine company, 2014,23 (03): 92-94.).
Fructus lycii is the traditional Chinese medicine in China, is the dry of Lycium barbarum L. of solanaceae (Lycium barbarum L.) Dry ripening fruits, alias beet.It is called in Compendium of Material Medica has the effect of liver protection kidney-nourishing, benefiting shrewd head.Research shows that: Chinese holly Matrimony vine has protection liver function, prevention and treatment diabetes, improves glaucoma lesion, reducing blood lipid, anti-aging, immunological regulation and antifatigue Etc. many effects (Teng Jun, Yuan Jia, Ye Shasha fructus lycii chemical component and pharmacological action correlation summarize [J] Strait Pharmaceutical Journal, 2014,26 (06): 36-37.).
Jujube is called jujube, thorn jujube, U.S. jujube, good jujube etc., is one of China's specialty, and jujube thin skin meat is thick, sweet moderate, battalion Support abundant, to nourish for autumn and winter good merchantable brand.China's jujube is divided into southern jujube, northern jujube two major classes." one
Three jujube of solar eclipse, at the age of one hundred years old to bear one's age well ".Jujube not still delicious fruit or tonic medicine, strengthen muscles and bones, promoting the circulation of qi of enriching blood, The effect of growing spleen moistening lung.Modern medicine study shows that jujube is hard to anaphylactoid purpura, anaemia, hypertension, acute, chronic hepatitis, liver Change, gastroenteric tumor are effective in cure.Furthermore jujube has antitumor, anti-aging, feeding spleen protect liver, decompression, prevention cardiovascular disease etc. Healthcare function (alimentary health-care function and development and utilization progress [J] value engineering of Wang Jinxi, Liu Hui a beautiful gem jujube, 2012, 31 (23): 290-292.).
STEVIA REBAUDIANA (Stevia rebaudiand Bertoni) also known as stevia rebaudianum, Sweet tea are that composite family perennial herb is planted Object.South American region resident has just utilized it to make Sweet tea before half a century, and just causes science until late nineteenth century Family note that the transplanting and habituation of STEVIA REBAUDIANA achieves very ten-strike, is largely planted as new sweet tea source plant by studying for many years Training.STEVIA REBAUDIANA contains several functions composition, including glycoside, flavonoids, chlorogenic acid etc., wherein glucoside compound kind Class is most, content is maximum (Wang Shaojia, outstanding sough STEVIA REBAUDIANA functional components progress [J] food industry science and technology, 2017, 38 (20): 323-327.).Steviol glycoside is a kind of natural high sugariness low heat value sweetener, be known as after sugarcane and beet it " third sugar source " afterwards is a kind of ideal sucrose succedaneum.Toxicological experiment show steviol glycoside do not have teratogenesis, Carcinogenic and mutagenic toxicity.In addition to applying in food, beverage as excellent sweetener, steviol glycoside also shows many function Can be active, such as (Wan Huida, Li Dan, summer chant plum steviol glycoside for blood pressure lowering, hypoglycemic, antitumor, antibacterial, anti diar rhea, solubilising Research on functional properties [J] Food Science of substance, 2015,36 (17): 264-269.).
Tea is deep by the favorite drink of our people, with the enhancing of people's health care consciousness, demand of the people to drink tea From the original function upgrading that quenches one's thirst to health care and diet function, with active prevention disease be main syllabus target health protection tea increasingly It has been favored by people.The type of health protection tea is although dazzling currently on the market, but few for the health protection tea of lowering fat and protecting liver It is few very few, it is far from satisfying the market demand.Therefore it develops and a variety of demands such as is suitble to people to take for a long time and meets lowering fat and protecting liver Health protection tea it is imperative.
Summary of the invention
In order to solve the problems in the existing technology, the present invention provides a kind of health-care tea for fat-reducing liver-fortifying and its preparation side Method, the effect of making it have lowering fat and protecting liver and preparation process is simple, reproducible.
In order to achieve the object of the present invention, the invention adopts the following technical scheme:
A kind of health-care tea for fat-reducing liver-fortifying, raw material is by green orchid, yellow mushroom, Swertia mussotii, black fungus, hawthorn, fructus lycii, jujube, sweet tea Ye Ju composition.
The parts by weight of the raw material are as follows: it is green 10~20 parts blue, 10~30 parts of yellow mushroom, 3~7 parts of Swertia mussotii, black fungus 15~35 parts, 5~15 parts of hawthorn, 5~15 parts of fructus lycii, 5~15 parts of jujube, 2~8 parts of STEVIA REBAUDIANA.
Blueness in the raw material is blue for one or both of dracocephalum heterophyllum, Herba Dracocephali Tangutici.
Swertia mussotii in the raw material is one of mussot swertia herb, Swertia franchetiana H.Smith, SISHU Herba Swertiae bimaculatae or a variety of.
A kind of preparation method of the health-care tea for fat-reducing liver-fortifying, comprising the following steps:
A. mixed the green orchid of raw material, yellow mushroom, Swertia mussotii, black fungus, hawthorn, fructus lycii, jujube, STEVIA REBAUDIANA by weight, It crushes, ethanol extract and the dregs of a decoction is obtained by filtration after extracting in ethyl alcohol;
B. dregs of a decoction step a separated separate after hot water extraction, and by aqueous extract and the dregs of a decoction;
C. after the aqueous extract obtained in the step a ethanol extract obtained and step b being mixed, it is concentrated into 1~3 times of specific gravity Paste;
D. auxiliary material is added in thick paste and softwood is made, dry particl, whole grain are dried at 60 DEG C, qualified grain is made in sieving, packs It gets product.
In the step a ethanol extract the preparation method comprises the following steps: by raw material mixed powder it is broken after, with 5~10 times of bodies of its quality The edible ethanol solution that product concentration is 95% impregnates 12~24 hours, the heating and refluxing extraction 1~3 time at a temperature of 45~65 DEG C, often Secondary 3 hours, through ethanol extract and the dregs of a decoction is obtained by filtration.
The preparation method of aqueous extract in the step b: 5~10 times of water are added in the dregs of a decoction of step a separation and decoct 3 again After hour, through aqueous extract and the dregs of a decoction is obtained by filtration.
The process conditions being concentrated in the step c are as follows: vacuum degree is 0.06~0.09MPa, and temperature is 50~65 DEG C.
Auxiliary material in the step d is one of citric acid, malic acid, ascorbic acid and tartaric acid or a variety of.
Auxiliary material additive amount in the step d is 5% ~ 10% of the paste weight obtained in the step c.
Compared with prior art, the beneficial effects of the present invention are: (1) present invention use edible ethanol and water step by step arithmetic Method, improve the solubility of effective component and the clarity of product, nutriment therein can be fully absorbed by making one body And effective component, to improve bioavilability;(2) low in cost, simple process of the invention is suitable for batch preparation and work Industry metaplasia produces, and has good market application prospect;(3) present invention is refined by the Natural Food medicinal material of dual-purpose of drug and food, is free of Any chemical synthesis substance, it is naturally environmentally friendly.Health-care tea for fat-reducing liver-fortifying obtained, it is safe and non-toxic, there is apparent liver protecting And effect for reducing blood fat, long-term use can promote metabolism, enhance immunity of organisms.
Detailed description of the invention
The green blue ethanol extract of Fig. 1 on the hepatitis mice serum transaminase that Con A induce influence to test in 8h when it is four groups small Mouse serum alt Activity determination experimental result.
The green blue ethanol extract of Fig. 2 on the hepatitis mice serum transaminase that Con A induce influence to test in 16h when it is four groups small Mouse serum alt Activity determination experimental result.
Fig. 3 is four groups small when green blue ethanol extract influences in experiment for 24 hours the hepatitis mice serum transaminase that Con A is induced Mouse serum alt Activity determination experimental result.
The green blue ethanol extract of Fig. 4 on the hepatitis mice serum transaminase that Con A induce influence to test in 8h when it is four groups small AST Activity determination experimental result in mouse serum.
The green blue ethanol extract of Fig. 5 on the hepatitis mice serum transaminase that Con A induce influence to test in 16h when it is four groups small AST Activity determination experimental result in mouse serum.
Fig. 6 is four groups small when green blue ethanol extract influences in experiment for 24 hours the hepatitis mice serum transaminase that Con A is induced AST Activity determination experimental result in mouse serum.
The experimental result that Fig. 7 health protection tea of the present invention influences hyperlipidemic mice lipid parameter.
Specific embodiment
Embodiment 1
A kind of health-care tea for fat-reducing liver-fortifying is made of the raw material of following portions by weight: green orchid 10 parts, 15 parts of yellow mushroom, Swertia mussotii 5 Part, 30 parts of black fungus, 15 parts of hawthorn, 5 parts of fructus lycii, 15 parts of jujube, 5 parts of STEVIA REBAUDIANA.
Wherein the green orchid is Herba Dracocephali Tangutici, dracocephalum heterophyllum by the mixing of 1:1 weight proportion.
Wherein the Swertia mussotii is mussot swertia herb, Swertia franchetiana H.Smith, SISHU Herba Swertiae bimaculatae by the mixing of 1:1:1 weight proportion.
A kind of preparation method of health-care tea for fat-reducing liver-fortifying, comprising the following steps:
A. the edible ethanol solution immersion 12 for being 95% with 5 times of volumetric concentrations of its quality after above-mentioned raw materials being mixed, crushed is small When, the heating and refluxing extraction 3 times at a temperature of 45 DEG C, 3 hours every time, through ethanol extract and the dregs of a decoction is obtained by filtration;
B. it will be added in the dregs of a decoction that step a is separated after 5 times of water decoct 3 hours again, through aqueous extract and the dregs of a decoction is obtained by filtration.
C. after the aqueous extract obtained in the step a ethanol extract obtained and step b being mixed, it is in vacuum degree 0.06MPa, temperature are concentrated under reduced pressure into 1 times of specific gravity of paste under the conditions of being 65 DEG C.
D. auxiliary material citric acid, malic acid, ascorbic acid, tartaric acid are mixed by 3 parts: 3 parts: 3 parts: 1 parts of weight proportion Afterwards, it is added by 5% weight ratio and softwood is made in thick paste, dry particl, whole grain are dried at 60 DEG C, qualification is made in sieving Grain, packaging are got product.
Embodiment 2
A kind of health-care tea for fat-reducing liver-fortifying is made of the raw material of following portions by weight: green orchid 13 parts, 20 parts of yellow mushroom, Swertia mussotii 6 Part, 35 parts of black fungus, 5 parts of hawthorn, 7 parts of fructus lycii, 8 parts of jujube, 6 parts of STEVIA REBAUDIANA.
It is wherein described green blue for Herba Dracocephali Tangutici;Swertia mussotii is mussot swertia herb.
A kind of preparation method of health-care tea for fat-reducing liver-fortifying, comprising the following steps:
A. the edible ethanol solution immersion 24 for being 95% with 10 times of volumetric concentrations of its quality after above-mentioned raw materials being mixed, crushed is small When, the heating and refluxing extraction 3 hours at a temperature of 65 DEG C, through ethanol extract and the dregs of a decoction is obtained by filtration;
B. it will be added in the dregs of a decoction that step a is separated after 10 times of water decoct 3 hours again, through aqueous extract and the dregs of a decoction is obtained by filtration.
C. after the aqueous extract obtained in the step a ethanol extract obtained and step b being mixed, it is in vacuum degree 0.09MPa, temperature are concentrated under reduced pressure into 3 times of specific gravity of paste under the conditions of being 50 DEG C.
D. it after mixing auxiliary material citric acid, malic acid by 5 parts: 5 parts of weight proportion, is added by 10% weight ratio thick Softwood is made in cream, dry particl, whole grain are dried at 60 DEG C, qualified grain is made, and packaging is got product in sieving.
Embodiment 3
A kind of health-care tea for fat-reducing liver-fortifying is made of the raw material of following portions by weight: green orchid 15 parts, 25 parts of yellow mushroom, Swertia mussotii 7 Part, 15 parts of black fungus, 8 parts of hawthorn, 10 parts of fructus lycii, 13 parts of jujube, 7 parts of STEVIA REBAUDIANA.
It is wherein described green blue for dracocephalum heterophyllum;Swertia mussotii is Swertia franchetiana H.Smith.
A kind of preparation method of health-care tea for fat-reducing liver-fortifying, comprising the following steps:
A. the edible ethanol solution immersion 18 for being 95% with 8 times of volumetric concentrations of its quality after above-mentioned raw materials being mixed, crushed is small When, heating and refluxing extraction 2 times at 50 °C, 3 hours every time, through ethanol extract and the dregs of a decoction is obtained by filtration.
B. it will be added in the dregs of a decoction that step a is separated after 7 times of water decoct 3 hours again, through aqueous extract and medicine is obtained by filtration Slag.
C. after the aqueous extract obtained in the step a ethanol extract obtained and step b being mixed, it is in vacuum degree 0.08MPa, temperature are concentrated under reduced pressure into 2 times of specific gravity of paste under the conditions of being 60 DEG C.
D. after mixing auxiliary material citric acid, malic acid, ascorbic acid by 2 parts: 3 parts: 5 parts of weight proportion, by 8% weight Softwood is made than adding in thick paste in amount, and dry particl is dried at 60 DEG C, whole grain, and qualified grain is made in sieving, pack up at Product.
Embodiment 4
A kind of health-care tea for fat-reducing liver-fortifying is made of the raw material of following portions by weight: green orchid 16 parts, 30 parts of yellow mushroom, Swertia mussotii 3 Part, 20 parts of black fungus, 10 parts of hawthorn, 12 parts of fructus lycii, 7 parts of jujube, 2 parts of STEVIA REBAUDIANA.
Wherein the green orchid is Herba Dracocephali Tangutici, dracocephalum heterophyllum by the mixing of 1:2 weight proportion.
Wherein the Swertia mussotii is SISHU Herba Swertiae bimaculatae.
A kind of preparation method of health-care tea for fat-reducing liver-fortifying, comprising the following steps:
A. the edible ethanol solution immersion 24 for being 95% with 6 times of volumetric concentrations of its quality after above-mentioned raw materials being mixed, crushed is small When, the heating and refluxing extraction 2 times at a temperature of 55 DEG C, 3 hours every time, through ethanol extract and the dregs of a decoction is obtained by filtration;
B. it will be added in the dregs of a decoction that step a is separated after 8 times of water decoct 3 hours again, through aqueous extract and the dregs of a decoction is obtained by filtration.
C. after the aqueous extract obtained in the step a ethanol extract obtained and step b being mixed, it is in vacuum degree 0.07MPa, temperature are concentrated under reduced pressure into 2 times of specific gravity of paste under the conditions of being 55 DEG C;
D. auxiliary material malic acid is added by 6% weight ratio and softwood is made in thick paste, dry particl is dried at 60 DEG C, it is whole Grain, sieving, is made qualified grain, packaging is got product.
Embodiment 5
A kind of health-care tea for fat-reducing liver-fortifying is made of the raw material of following portions by weight: green orchid 20 parts, 10 parts of yellow mushroom, Swertia mussotii 4 Part, 25 parts of black fungus, 13 parts of hawthorn, 15 parts of fructus lycii, 5 parts of jujube, 8 parts of STEVIA REBAUDIANA.
Wherein the green orchid is Herba Dracocephali Tangutici, dracocephalum heterophyllum by the mixing of 2:1 weight proportion.
Wherein the Swertia mussotii is Swertia franchetiana H.Smith, SISHU Herba Swertiae bimaculatae by the mixing of 2:1 weight proportion.
A kind of preparation method of health-care tea for fat-reducing liver-fortifying, comprising the following steps:
A. the edible ethanol solution immersion 12 for being 95% with 9 times of volumetric concentrations of its quality after above-mentioned raw materials being mixed, crushed is small When, the heating and refluxing extraction 3 times at a temperature of 60 DEG C, 3 hours every time, through ethanol extract and the dregs of a decoction is obtained by filtration;
B. it will be added in the dregs of a decoction that step a is separated after 6 times of water decoct 3 hours again, through aqueous extract and the dregs of a decoction is obtained by filtration.
C. after the aqueous extract obtained in the step a ethanol extract obtained and step b being mixed, it is in vacuum degree 0.06MPa, temperature are concentrated under reduced pressure into 3 times of specific gravity of paste under the conditions of being 50 DEG C;
D. after mixing auxiliary material citric acid, ascorbic acid, tartaric acid by 4 parts: 5 parts: 1 part of weight proportion, by 9% weight ratio It adds and softwood is made in thick paste, dry particl, whole grain are dried at 60 DEG C, qualified grain is made, and packaging is got product in sieving.
Embodiment 6
Influence of the green orchid ethanol extract to the Con A hepatitis mice serum transaminase induced:
The reaction of liver excessive immune is caused to simulate necrosis of liver cells and liver organization caused by Autoimmune Disorders using Con A Damage pathology.In the pathological model, ammonia is turned to Balb/c mouse by detection control group and green blue ethanol extract group (DH) Therapeutic effect of the green blue ethanol extract to autoimmune hepatic injury is evaluated in the variation of enzymatic activity.Table 1 is pressed in experiment in vivo grouping The method after being handled every group respectively at 8,16, carry out Enzyme target (ALT, AST) active detection for 24 hours.
The experiment process that the green blue ethanol extract of table 1 acts on hepatitis mice transaminase
ALT, AST are active in four groups of mice serums of each time point changes (note: with control group ratio as shown in figures 1-6 Compared with p<0.01 * * * p>0.05, * * p<0.05, *.).From Fig. 1-6 it can be seen that green blue ethanol extract damages autoimmune liver Wound has significant therapeutic effect.
Embodiment 7
Influence of the health protection tea of the present invention to hyperlipidemic mice lipid parameter:
Mouse is fed with high lipid food and establishes high blood lipid model, using simvastatin as positive control medicine, with embodiment 1, reality It applies example 3 and embodiment 4 is used as lipid-loweringing experimental drug, by the lipid-lowering therapy to mouse high in fat, more pretherapy and post-treatment mice serum Total cholesterol (TC), total triglycerides (TG), low-density total cholesterol (LDL-C), high density total cholesterol (HDL-C) content, The research present invention influences high blood lipid model lipid of mice.Experiment in vivo grouping is handled by method described in table 2.
Experiment process of the health protection tea of the present invention of table 2 to hyperlipidemic mice effect for reducing fat
From attached drawing 7 it can be seen that health protection tea described in the embodiment of the present invention 1, embodiment 3 and embodiment 4 can reduce height It is horizontal to improve HDL-C for the content of TC, TG and LDL-C of blood lipid mouse.

Claims (10)

1. a kind of health-care tea for fat-reducing liver-fortifying, which is characterized in that the raw material of the health-care tea for fat-reducing liver-fortifying is by green orchid, yellow mushroom, hiding mattress Old, black fungus, hawthorn, fructus lycii, jujube, STEVIA REBAUDIANA composition.
2. a kind of health-care tea for fat-reducing liver-fortifying according to claim 1, which is characterized in that the parts by weight of the raw material are as follows: It is green 10~20 parts blue, 10~30 parts of yellow mushroom, 3~7 parts of Swertia mussotii, 15~35 parts of black fungus, 5~15 parts of hawthorn, fructus lycii 5~ 15 parts, 5~15 parts of jujube, 2~8 parts of STEVIA REBAUDIANA.
3. a kind of health-care tea for fat-reducing liver-fortifying according to claim 1, which is characterized in that the blueness in the raw material is blue for different leaf One or both of green blue, Herba Dracocephali Tangutici.
4. a kind of health-care tea for fat-reducing liver-fortifying according to claim 1, which is characterized in that the Swertia mussotii in the raw material is river One of western Swertia patens, Swertia franchetiana H.Smith, SISHU Herba Swertiae bimaculatae are a variety of.
5. a kind of preparation method of health-care tea for fat-reducing liver-fortifying according to claim 1, it is characterised in that the following steps are included:
A. mixed the green orchid of raw material, yellow mushroom, Swertia mussotii, black fungus, hawthorn, fructus lycii, jujube, STEVIA REBAUDIANA by weight, It crushes, ethanol extract and the dregs of a decoction is obtained by filtration after extracting in ethyl alcohol;
B. aqueous extract and the dregs of a decoction is obtained by filtration after hot water extraction in dregs of a decoction step a separated;
C. after the aqueous extract obtained in the step a ethanol extract obtained and step b being mixed, it is concentrated into 1~3 times of specific gravity Paste;
D. auxiliary material is added in thick paste and softwood is made, dry particl, whole grain are dried at 60 DEG C, qualified grain is made in sieving, packs It gets product.
6. a kind of preparation method of health-care tea for fat-reducing liver-fortifying according to claim 5, which is characterized in that in the step a Ethanol extract the preparation method comprises the following steps: by raw material mixed powder it is broken after, with 5~10 times of volumetric concentrations of its quality be 95% edible second Alcoholic solution impregnates 12~24 hours, the heating and refluxing extraction 1~3 time at a temperature of 45~65 DEG C, and 3 hours every time, through being obtained by filtration Ethanol extract and the dregs of a decoction.
7. a kind of preparation method of health-care tea for fat-reducing liver-fortifying according to claim 5, which is characterized in that in the step b Aqueous extract the preparation method comprises the following steps: being added in the dregs of a decoction of step a separation after 5~10 times of water decoct 3 hours again, through being obtained by filtration Aqueous extract and the dregs of a decoction.
8. a kind of preparation method of health-care tea for fat-reducing liver-fortifying according to claim 5, which is characterized in that in the step c The process conditions of concentration are as follows: vacuum degree is 0.06~0.09MPa, and temperature is 50~65 DEG C.
9. a kind of preparation method of health-care tea for fat-reducing liver-fortifying according to claim 5, which is characterized in that in the step d Auxiliary material be one of citric acid, malic acid, ascorbic acid and tartaric acid or a variety of.
10. a kind of preparation method of health-care tea for fat-reducing liver-fortifying according to claim 5, which is characterized in that the step d In auxiliary material additive amount be 5% ~ 10% of the paste weight obtained in the step c.
CN201810885243.6A 2018-08-06 2018-08-06 A kind of health-care tea for fat-reducing liver-fortifying and preparation method thereof Pending CN109043030A (en)

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Application publication date: 20181221