CN108935939A - Lipotropic rheum officinale fish feed additive - Google Patents

Lipotropic rheum officinale fish feed additive Download PDF

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Publication number
CN108935939A
CN108935939A CN201810873032.0A CN201810873032A CN108935939A CN 108935939 A CN108935939 A CN 108935939A CN 201810873032 A CN201810873032 A CN 201810873032A CN 108935939 A CN108935939 A CN 108935939A
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parts
herb
lipotropic
fermentation
fish feed
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许飞
韦玉
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Hefei River Duo Bao Agricultural Development Co Ltd
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Hefei River Duo Bao Agricultural Development Co Ltd
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    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/12Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
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    • A23KFODDER
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    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K40/00Shaping or working-up of animal feeding-stuffs
    • A23K40/10Shaping or working-up of animal feeding-stuffs by agglomeration; by granulation, e.g. making powders
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/80Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/68Plantaginaceae (Plantain Family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/82Theaceae (Tea family), e.g. camellia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/19Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87Re-use of by-products of food processing for fodder production

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Abstract

The invention proposes a kind of lipotropic rheum officinale fish feed additives, calculate according to weight percent, including following raw material: herb fermenting extract 40~60%, glycine betaine 20~30%, inositol 10~20% and minerals 5~10%;Wherein, the herb fermenting extract is mainly prepared by oriental wormwood, flaccid knotweed herb, Radix Angelicae Sinensis, green tea, Asiatic plantain, emblic and dried orange peel by lactobacillus plantarum and fermentation by saccharomyces cerevisiae.The additive can be directly added into fish feed, reduce fish body fat deposits, safeguard the normal physiological function of liver organization, promote Larimichthys crocea digestion and feed, so that Larimichthys crocea edible portion accounting increases.

Description

Lipotropic rheum officinale fish feed additive
Technical field
The invention belongs to field of feed additive technology, and in particular to a kind of lipotropic Larimichthys crocea feed addition Agent.
Background technique
Larimichthys crocea is the important economic fish in China, and due to excessive fishing, yield sharply declines.China Larimichthys crocea in 1987 Artificial breeding succeeds and started to propagate artificially in 1994.But cultured large yellow croaker figure is poor, and flesh of fish mouthfeel, nutritive value are remote Not as good as Wild Rhubarb fish (Duan Qingyuan etc., 2000), a large number of studies show that, fatty over-deposit is the weight for influencing figure, mouthfeel Want one of factor (Miao Furong etc. 2008;Xu Jilin etc., 2005).And because of a large amount of depositions of fat, fatty liver in breeding process High rate seriously affected the Larimichthys crocea speed of growth and cultivation economic benefit (Liu Zhen is brave etc., 2007;Once end etc., 2008) sustainable development of rheum officinale fish culture, is constrained.
Under the conditions of intensive high-density breeding, breeding environment deteriorates, largely using anti-battalion in antibiotic medicine, feedstuff The presence etc. for supporting the factor all can cause to damage to cultivated animals liver and gallbladder, cause to occur becoming main with liver and bladder disease in current cultivation The disease in the liver and gallbladder syndrome of feature.Hepatic disease causes liver function that obstacle occurs, and influences being absorbed and utilized for nutriment, is immunized Function reduces, anti-stress ability and premunition decline, and then influences aquatic livestock normal growth, and culture efficiency is caused to be damaged Evil.
Summary of the invention
The present invention proposes that a kind of lipotropic rheum officinale fish feed additive, the additive can be directly added into fish feed In, fish body fat deposits are reduced, safeguard the normal physiological function of liver organization, promote Larimichthys crocea digestion and feed, so that greatly Yellow croaker edible portion accounting increases.
The technical scheme of the present invention is realized as follows:
A kind of lipotropic rheum officinale fish feed additive, calculates, including following raw material according to weight percent:
Herb fermenting extract 40~60%, glycine betaine 20~30%, inositol 10~20% and minerals 5~10%;Its In, the herb fermenting extract mainly passes through plant by oriental wormwood, flaccid knotweed herb, Radix Angelicae Sinensis, green tea, Asiatic plantain, emblic and dried orange peel Lactobacillus is prepared with fermentation by saccharomyces cerevisiae.
Preferably, in the herb fermenting extract each raw material parts by weight are as follows: 20~30 parts of oriental wormwood, flaccid knotweed herb 12~ 16 parts, 3~6 parts of Radix Angelicae Sinensis, 4~8 parts of green tea, 1~2 part of Asiatic plantain, 2~4 parts of emblic and 1~2 part of dried orange peel.
Preferably, the preparation method of the herb fermenting extract, comprising the following steps:
1) water is added to carry out boiling, mistake after weighing oriental wormwood, flaccid knotweed herb, Radix Angelicae Sinensis, green tea, Asiatic plantain, emblic and dried orange peel mixing Filter obtains filtrate and filter residue;
2) filter residue of step 1) is put into beater and suitable quantity of water is added and carry out mashing processing, obtain slurries;
3) into the slurries of step 2), inoculated plant lactobacillus ferments, and fermentation temperature is 30~33 DEG C, fermentation time It for 6~10h, then inoculates saccharomycete and ferments, fermentation temperature is 26~30 DEG C, and fermentation time is for 24 hours~36h, then Stop fermentation, fermentation liquid carries out filter at low temperature, obtains filtrate, then Granulating process.
Preferably, the additive amount of the lactobacillus plantarum is the 1~3% of the slurry weight, the addition of the saccharomycete Amount is the 4~8% of the slurry weight.
Lipotropic Larimichthys crocea feed addictive preparation method of the invention: above-mentioned raw materials are mixed stir according to the proportion It mixes uniformly.
The primary efficacy of each raw material is as follows in herb fermenting extract in the present invention:
Oriental wormwood clearing heat and promoting diuresis;Removing jaundice.The major functions: jaundice, difficult urination, itchy sore, infectious jaundice type hepatitis etc..Pharmacology The effects of learning research has cholagogue, and liver function protecting is antipyretic, anti-inflammatory, reducing blood lipid, decompression, coronary dilatation.
Flaccid knotweed herb, congener polygonum flaccidum, water pepper, false long-tail knotweed and this product herb, be used as medicine as polygonum flaccidum in different regions. Swelling and pain relieving.Control early stage of pyogenic infection of skin, dysentery abdominal pain.
Radix Angelicae Sinensis, replenishing and activating blood, menstruction regulating and pain relieving, relax bowel and defecation.Belong to the antianaemics of qi-restoratives medicine subordinate classification.
Green tea refers to the young leaves or bud for taking tea tree, not fermented, the drink made through techniques such as water-removing, shaping, drying Product.The color of its manufactured goods and the more green style for saving fresh tea passes of millet paste after brewing.Often drink green tea can give protection against cancer, and drop Rouge and weight-reducing also can reduce its nicotine injury being subject to smoker.
Asiatic plantain is clearing damp and promoting diuresis Chinese medicine, the major functions: main difficult urination, under the turbid belt, edema swelling, summer-heat and damp dysentery, hot eyes It hides from view, the asthma of phlegm heat-syndrome cough.Semen plantaginis is first recorded in Shennong's Herbal: Chinese herbaceous peony is just used as medicine with seed.
Emblic, 304 years Shanxi generations just first recorded in " southern vegetation shape ", former translated name claims emblic leafflower fruit, clearing heat and detoxicating to commonly use Medicine.Clearing heat and cooling blood, food digesting stomach fortifying, cough-relieving of promoting the production of body fluid.Belong to digestants.
Beneficial effects of the present invention:
Herb fermenting extract in additive of the invention is distinguished traditional Chinese medicine and is boiled and alcohol extracting thing, and the present invention will Traditional Chinese medicine boils the dregs of a decoction (present invention in for filter residue) for extracting and giving it up, and is handled by mashing, then with lactobacillus plantarum and Fermentation process is carried out before and after saccharomycete, it can be sufficiently by the ingredient of dregs of a decoction raw material itself (the also traditional water of the ingredient and alcohol extracting The non-principal component not having in liquid) it decomposites and, according to the compatibility guideline of Chinese medicine between them, on the one hand promote to disappear in fish body Change the expression of related gene, so that the nutritional ingredient being digested is converted to protein and muscle etc., on the other hand enhances body Oxygen uptake ability, so that Larimichthys crocea is more active, looking for food property is higher, and the common feeding of the application additive is less added in fish body activity The daily number of activities of material group improve 21~30%, and the activity time extends 32~65min daily.In addition, the present invention uses plant The lactobacillus prior fermentation dregs of a decoction will can activate the active material of metabolic enzyme to release well.
Additive of the invention can be directly added into fish feed, can safeguard the normal physiological function of liver organization, energy It is enough obviously promoted the metabolism of Larimichthys crocea body fat, the deposition of Larimichthys crocea body fat can be substantially reduced, it is final to prevent " liver and gallbladder Syndrome ", it is ensured that healthy fish
Specific embodiment
Embodiment 1
The parts by weight of each raw material in herb fermenting extract are as follows: 24 parts of oriental wormwood, 14 parts of flaccid knotweed herb, 5 parts of Radix Angelicae Sinensis, green tea 6 Part, 1 part of Asiatic plantain, 3 parts of emblic and 2 parts of dried orange peel.
The preparation method of herb fermenting extract, comprising the following steps:
1) water is added to carry out boiling, mistake after weighing oriental wormwood, flaccid knotweed herb, Radix Angelicae Sinensis, green tea, Asiatic plantain, emblic and dried orange peel mixing Filter obtains filtrate and filter residue;
2) filter residue of step 1) is put into beater and suitable quantity of water is added and carry out mashing processing, obtain slurries;
3) into the slurries of step 2), inoculated plant lactobacillus ferments, and fermentation temperature is 24 DEG C, fermentation time 5h, Then it inoculates saccharomycete to ferment, fermentation temperature is 28 DEG C, fermentation time 30h, then stops fermentation, and fermentation liquid carries out Filter at low temperature obtains filtrate, then Granulating process.The additive amount of lactobacillus plantarum is the 2% of slurry weight, saccharomycete Additive amount be slurry weight 6%.
Embodiment 2
The parts by weight of each raw material in herb fermenting extract are as follows: 20 parts of oriental wormwood, 16 parts of flaccid knotweed herb, 3 parts of Radix Angelicae Sinensis, green tea 4 Part, 2 parts of Asiatic plantain, 2 parts of emblic and 1 part of dried orange peel.
The preparation method of herb fermenting extract, comprising the following steps:
1) water is added to carry out boiling, mistake after weighing oriental wormwood, flaccid knotweed herb, Radix Angelicae Sinensis, green tea, Asiatic plantain, emblic and dried orange peel mixing Filter obtains filtrate and filter residue;
2) filter residue of step 1) is put into beater and suitable quantity of water is added and carry out mashing processing, obtain slurries;
3) into the slurries of step 2), inoculated plant lactobacillus ferments, and fermentation temperature is 21 DEG C, fermentation time 6h, Then it inoculates saccharomycete to ferment, fermentation temperature is 30 DEG C, and fermentation time is for 24 hours, then to stop fermentation, and fermentation liquid carries out Filter at low temperature obtains filtrate, then Granulating process.The additive amount of lactobacillus plantarum is the 1% of slurry weight, saccharomycete Additive amount be slurry weight 4%.
Embodiment 3
The parts by weight of each raw material in herb fermenting extract are as follows: 30 parts of oriental wormwood, 12 parts of flaccid knotweed herb, 6 parts of Radix Angelicae Sinensis, green tea 8 Part, 1 part of Asiatic plantain, 4 parts of emblic and 2 parts of dried orange peel
The preparation method of herb fermenting extract, comprising the following steps:
1) water is added to carry out boiling, mistake after weighing oriental wormwood, flaccid knotweed herb, Radix Angelicae Sinensis, green tea, Asiatic plantain, emblic and dried orange peel mixing Filter obtains filtrate and filter residue;
2) filter residue of step 1) is put into beater and suitable quantity of water is added and carry out mashing processing, obtain slurries;
3) into the slurries of step 2), inoculated plant lactobacillus ferments, and fermentation temperature is 26 DEG C, fermentation time 4h, Then it inoculates saccharomycete to ferment, fermentation temperature is 26 DEG C, fermentation time 36h, then stops fermentation, and fermentation liquid carries out Filter at low temperature obtains filtrate, then Granulating process.The additive amount of lactobacillus plantarum is the 3% of slurry weight, saccharomycete Additive amount be slurry weight 8%.
Embodiment 4
A kind of lipotropic rheum officinale fish feed additive, calculates, including following raw material according to weight percent:
Herb fermenting extract 50%, glycine betaine 20%, inositol 20%, the minerals 10% of embodiment 1.
Embodiment 5
A kind of lipotropic rheum officinale fish feed additive, calculates, including following raw material according to weight percent:
Herb fermenting extract 55%, glycine betaine 25%, inositol 10%, the minerals 10% of embodiment 2.
Embodiment 6
A kind of lipotropic rheum officinale fish feed additive, calculates, including following raw material according to weight percent:
Herb fermenting extract 60%, glycine betaine 20%, inositol 15%, the minerals 5% of embodiment 3.
Embodiment 7
A kind of lipotropic rheum officinale fish feed additive, calculates, including following raw material according to weight percent:
Herb fermenting extract 46%, glycine betaine 24%, inositol 20%, the minerals 10% of embodiment 2.
Test example
Experimental animal selection starts to test with the essentially identical Larimichthys crocea prelarva of batch of, bouncing, size weight, just Initial body weight are as follows: 8.3 ± 0.2g;Basal feed group is set, at invention group (+3% weight ratio feed addictive of basal feed) 5 Reason, each processing set 6 repetitions, and experiment carries out 12 weeks altogether, after experiment, measure survival rate, rate of body weight gain, total fat contains Amount, hepatic fat content, the indexs such as liver body ratio, and data statistic analysis is carried out, it the results are shown in Table 1.
Table 1
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention Within mind and principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.

Claims (4)

1. a kind of lipotropic rheum officinale fish feed additive, which is characterized in that calculated according to weight percent, including following Raw material:
Herb fermenting extract 40~60%, glycine betaine 20~30%, inositol 10~20% and minerals 5~10%;Wherein, institute Herb fermenting extract is stated mainly by oriental wormwood, flaccid knotweed herb, Radix Angelicae Sinensis, green tea, Asiatic plantain, emblic and dried orange peel by lactobacillus plantarum It is prepared with fermentation by saccharomyces cerevisiae.
2. lipotropic rheum officinale fish feed additive according to claim 1, which is characterized in that the herb fermenting The parts by weight of each raw material in extract are as follows: 20~30 parts of oriental wormwood, 12~16 parts of flaccid knotweed herb, 3~6 parts of Radix Angelicae Sinensis, 4~8 parts of green tea, 1~2 part of Asiatic plantain, 2~4 parts of emblic and 1~2 part of dried orange peel.
3. lipotropic rheum officinale fish feed additive according to claim 2, which is characterized in that the herb fermenting The preparation method of extract, comprising the following steps:
1) add water to carry out boiling after weighing oriental wormwood, flaccid knotweed herb, Radix Angelicae Sinensis, green tea, Asiatic plantain, emblic and dried orange peel mixing, filter To filtrate and filter residue;
2) filter residue of step 1) is put into beater and suitable quantity of water is added and carry out mashing processing, obtain slurries;
3) into the slurries of step 2), inoculated plant lactobacillus ferments, fermentation temperature be 30~33 DEG C, fermentation time be 6~ Then 10h inoculates saccharomycete and ferments, fermentation temperature is 26~30 DEG C, and fermentation time is for 24 hours~36h, then stops hair Ferment, fermentation liquid carry out filter at low temperature, obtain filtrate, then Granulating process.
4. lipotropic rheum officinale fish feed additive according to claim 1, which is characterized in that the plant cream bar The additive amount of bacterium is the 1~3% of the slurry weight, and the additive amount of the saccharomycete is the 4~8% of the slurry weight.
CN201810873032.0A 2018-08-02 2018-08-02 Lipotropic rheum officinale fish feed additive Withdrawn CN108935939A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116998593A (en) * 2023-09-15 2023-11-07 广东省科学院微生物研究所(广东省微生物分析检测中心) Application of lactobacillus plantarum in preparation for improving fish sugar tolerance

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116998593A (en) * 2023-09-15 2023-11-07 广东省科学院微生物研究所(广东省微生物分析检测中心) Application of lactobacillus plantarum in preparation for improving fish sugar tolerance

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