CN108904616A - A kind of Chinese materia medica preparation for treating affection of exogenous wind-cold - Google Patents

A kind of Chinese materia medica preparation for treating affection of exogenous wind-cold Download PDF

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CN108904616A
CN108904616A CN201811101088.0A CN201811101088A CN108904616A CN 108904616 A CN108904616 A CN 108904616A CN 201811101088 A CN201811101088 A CN 201811101088A CN 108904616 A CN108904616 A CN 108904616A
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cold
chinese
materia medica
exogenous wind
preparation
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李小军
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of Chinese materia medica preparation for treating affection of exogenous wind-cold, being in parts by weight includes following traditional Chinese medicine ingredients:Chinese ephedra 6g, ramulus cinnamomi 4g, almond 9g(Peeling point), radix glycyrrhizae preparata 3g.The preparation and application of the traditional chinese medicine composition of the invention:Chinese ephedra is first added nine liters of water, (i.e. high fire) is endured out with high heat, is used mild fire (small fire) after boiling instead and is kept slight boiling condition, is boiled to two liters of reduction, offscum is skimmed, its excess-three taste medicine is added, continues to decoct, finally boil and take two and half, medicine is filtered, divides and takes in the morning and evening, warmly take.

Description

A kind of Chinese materia medica preparation for treating affection of exogenous wind-cold
Technical field
The invention belongs to Chinese medicine compositions, specifically, being to be related to a kind of Chinese materia medica preparation for affection of exogenous wind-cold treatment.
Background technique
Flu is a kind of multiple diseases, and market is very big to the demand of cold medicine.Estimate according to the insiders, with China 1000000000 populations have the every annual meeting of half people to obtain flu more than once, spend in 10 to 50 yuan of calculating, the city of China's cold drug every time Market share is about 5,000,000,000 yuan or more;Optimistic estimation is to sell more than 10,000,000,000 yuans in year.But Chinese cold drug city Nearly all occupied by the internationally renowned brand from foreign countries, the market share of home products is extremely small for field.Right PPA event SARS with 2003 makes people see the market space that Western medicine leaves Chinese medicine for, sees many traditional Chinese medicine enterprises huge Commercial opportunity, the tempting market space attracts numerous pharmaceutical manufacturers to start to pay attention to Chinese medicine cold drug, and Chinese medicine conventional dosage forms are treated The pursuit that the rhythm of life and people that disease does not adapt to modernization gradually are easy to medication, effect is aobvious, therefore develop one kind Bioavilability is high, dosage form is advanced, curative effect is affirmed, just by enterprises and is researched and developed unit by the new formulation of patient's hobby Very big concern.
Flu is the four seasons common exterior syndrome, especially common with winter and spring.Many families be equipped with treatment flu at Medicine, somebody has eaten many medicines after catching a cold, but illness does not mitigate.Key is no diagnosis and prescription.Chinese medicine thinks to catch a cold It generally can be divided into anemofrigid cold and anemopyretic cold two major classes.Both flu etiology and pathogenesis, symptom, principle of reatment and medication are poor It is very not big.Anemofrigid cold, cause are usually fatigue, are not rested, along with drying or suffer from cold, the anemofrigid cold usual autumn and winter Occur relatively more.Anemofrigid cold, which is that the heresy of chill is outer, attacks, caused by Lung Qi obstraction.Symptom is visible:Aversion to cold is heavy, it is light, lossless to generate heat, It is thin white that headache bodily pain, stuffy nose with watery discharge, cough spit dilute white phlegm, not thirsty or thirsty hot drink preference, tongue fur.Therapy should be with relieving the exterior syndrome with drugs pungent in flavor and warm in property It is main.Currently, medication on the market is relatively simple, when use, tends not to reach people's expected effect.
Summary of the invention
The present invention provides a kind of Chinese materia medica preparation for treating affection of exogenous wind-cold, with the continuous development of China's traditional Chinese medicine, In treatment affection of exogenous wind-cold, the advantages of people gradually appreciate Chinese traditional treatment above-mentioned disease, and poison is secondary over the course for the treatment of makees Restore strong early for the status of existing western medical treatment affection of exogenous wind-cold with the advantages such as small, expense is low to solve affection of exogenous wind-cold patient The problem of health, the drug are that have the characteristics that quick, significant in efficacy using common Chinese medicine as raw material, and can effectively be treated State one disease of affection of exogenous wind-cold.
In order to achieve the above-mentioned object of the invention, the raw material composition and its weight proportion of the effective ingredient is made in the present invention For:Chinese ephedra 6g, ramulus cinnamomi 4g, almond 9g(Peeling point), radix glycyrrhizae preparata 3g.
The preparation and application of the traditional chinese medicine composition of the invention:Chinese ephedra is first added nine liters of water, (i.e. high fire) is endured out with high heat, It uses mild fire (small fire) after boiling instead and keeps slight boiling condition, boil to reducing two liters, skim offscum, add its excess-three taste medicine, continue It decocts, finally boils and take two and half, medicine is filtered, divide and take in the morning and evening, warmly take.
Invention selects natural drug, for affection of exogenous wind-cold etiology and pathogenesis, each taste for treating the Chinese materia medica preparation of affection of exogenous wind-cold Medicinal material respectively has its effect, coordinates mutually, and Chinese ephedra is bitterly warm-natured, is the special medicine of lung channel, can send out more human body, there is inducing sweat and dispelling exogenous evils, declare The effect that lung is relievingd asthma, monarch drug in a prescription in the side of being;Due to seek it is puckery defend strongly fragrant, Chinese ephedra sweating is applied alone, but Xie Wei gas is strongly fragrant, so again with temperature through dissipating Cold, battalion is minister up to the ramulus cinnamomi defended thoroughly, reinforces inducing sweat and dispelling exogenous evils and dispersing wind and cold, except body aches;The asthma of assertive evidence is strongly fragrant by lung qi and superinverse institute Cause, Chinese ephedra, ramulus cinnamomi again all uplink and dissipate, so again with drop lung qi, dispersing wind and cold almond be adjutant, with Chinese ephedra one a surname one drop, increasing The strongly fragrant function relievingd asthma of strong solution;Radix glycyrrhizae preparata, which can reconcile, declares the fiber crops of drop, apricot and mitigates fiber crops, the high strong property that osmanthus is harmonious, and makes sweating not Cause too quickly and damage healthy tendency, be make medicine and and adjutant justice.
Specific embodiment
Embodiment 1:A kind of Chinese materia medica preparation for treating affection of exogenous wind-cold includes following traditional Chinese medicine ingredients in parts by weight:Chinese ephedra 6g, Ramulus cinnamomi 4g, almond 9g(Peeling point), radix glycyrrhizae preparata 3g.
Embodiment 2:If patient's general aching on the patient susceptible to damp pathogen, Rhizoma Atractylodis Macrocephalae 9g is added in said components.
Embodiment 3:If patient's rheumatism general aching on the body, fever, and increasingly pain, Chinese ephedra 3g, apricot are added in said components Benevolence 3g, semen coicis 3g.
Embodiment 4:If patient's fever with chilliness, fever and chills all weigh, floating and tense pulse, body pain, restlessness without perspiration, at above-mentioned group Add Chinese ephedra 3g, gypsum 12g in point(It is broken), ginger 9g, 3 pieces of jujube(Thumb).
Embodiment 5:If patient's cough with dyspnea, mental disorder is unfavorable, sips sound, superficial and rapid pulse, the Jia Sangbai in said components Skin 3g(Honey toast), perilla seed 3g, poria cocos 3g(Peeling), dried orange peel 3g.
Chinese ephedra is first added nine liters of water, (i.e. high fire) is endured out with high heat, and it uses mild fire (small fire) after boiling instead and keeps slight boiling condition, It boils to reducing two liters, skims offscum, add its excess-three taste medicine, continue to decoct, finally boil and take two and half, medicine is filtered, divide early Evening takes, and warmly takes.
The clinical treatment effect of the Chinese medicine preparation of the present invention for affection of exogenous wind-cold nursing is illustrated below by way of practical example Fruit.
1, clinical data
All cases are hospital outpatient patient, and totally 180, wherein male 100, female 80;Age is 18-54 years old (average 39 Year);Course of disease 1-6 (3 days average), therapeutic scheme gives prescription of the present invention and is decocted in water for oral dose, one dose per day, sweating, avoids eating during treatment pungent The object of peppery raw meat hair, observation index symptom:Fever, aches all over, nasal congestion, brings up phlegm when one coughs, rear head pain, and neck rotation is ineffective It is living.The pretherapy and post-treatment variation of observation.Duration of medication clinical symptoms and the every day entry of sign 1 time, adverse reaction records at any time.
2, criterion of therapeutical effect
Clinical cure:Body temperature is normal, and from head to foot without ache sense, no nasal obstruction stream coughs and disappears, no phlegm, and neck is painless;
It is effective:Body temperature is normal, and from head to foot without ache sense, no nasal obstruction stream, slight to cough, phlegm, neck are painless less;
Effectively:Body temperature is normal, from head to foot slightly ache sense, and no nasal obstruction stream, cough mitigates, few phlegm, neck slightly feeling of pain;
In vain:Pretherapy and post-treatment symptom is without improvement or aggravates.
3, treatment results
Therapeutic effect:In the clinical observation case, the 2-3 course for the treatment of of taking medicine is fully recovered 104, follow-up no relapse, and effective 55, Effective 16, invalid 5, total effective rate 97.2%, middle adverse drug reaction(ADR)Evaluation, adverse reaction and poison pair do not occur Effect.
Typical case:
Old ×, male, 29 years old.Because chilly, fever were gone to a doctor with vomiting, diarrhea one day.Before patient one day because of " suffering from cold " after, it is consciously complete Body is uncomfortable, and chilly, abdomen are bored swollen, do not feel like eating.Vomiting is gastric content twice, diarrhea four times, stool amount is more, it is thin, Have foam, without mucopurulent bloody stool, without tenesmus, abdominal pain is unobvious.It looks into:General 38.5 DEG C of body temperature, pharynx is red, abdomen is soft, without obvious Tenderness, bowel sounds active.Stool routine examination:It is dilute, yellow to have swill.Chinese medicine summarized pulse records:Abdominal pain, bowel sounds active.Stool routine examination: It is dilute, yellow to have swill.Blood routine is without exception.Diagnosis:Common cold of gastrointestinal type.Chinese medicine summarized pulse records:Abdominal pain, borborygmus, diarrhea, stool are sense By the card of cold-dampness.To drug of the invention is taken, three times a day, it even served three days, subjective symptoms obviously subtracts after patient takes one day Gently, without vomiting, diarrhea twice, can feed a little, after three days symptom disappear, diet can, stool forming.

Claims (6)

1. a kind of Chinese materia medica preparation for treating affection of exogenous wind-cold, it is characterised in that:The Chinese medicine preparation includes following Chinese medicine in parts by weight Ingredient:Chinese ephedra 6g, ramulus cinnamomi 4g, almond 9g(Peeling point), radix glycyrrhizae preparata 3g.
2. a kind of Chinese materia medica preparation for treating affection of exogenous wind-cold as described in claim 1, it is characterised in that:The Chinese medicine preparation further includes Rhizoma Atractylodis Macrocephalae 9g.
3. a kind of Chinese materia medica preparation for treating affection of exogenous wind-cold as described in claim 1, it is characterised in that:The Chinese medicine preparation further includes Chinese ephedra 3g, almond 3g, semen coicis 3g.
4. a kind of Chinese materia medica preparation for treating affection of exogenous wind-cold as described in claim 1, it is characterised in that:The Chinese medicine preparation further includes Chinese ephedra 3g, gypsum 12g(It is broken), ginger 9g, 3 pieces of jujube(Thumb).
5. a kind of Chinese materia medica preparation for treating affection of exogenous wind-cold as described in claim 1, it is characterised in that:The Chinese medicine preparation further includes Root bark of white mulberry 3g(Honey toast), perilla seed 3g, poria cocos 3g(Peeling), dried orange peel 3g.
6. a kind of preparation method for the Chinese materia medica preparation for treating affection of exogenous wind-cold as described in claim 1, it is characterised in that:It first will be numb Huang adds nine liters of water, and (i.e. high fire) is endured out with high heat, uses mild fire (small fire) after boiling instead and keeps slight boiling condition, boils to two liters of reduction, Offscum is skimmed, its excess-three taste medicine is added, continues to decoct, finally boil and take two and half, medicine is filtered, divides and takes in the morning and evening, warmly take.
CN201811101088.0A 2018-09-20 2018-09-20 A kind of Chinese materia medica preparation for treating affection of exogenous wind-cold Withdrawn CN108904616A (en)

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