CN108853416A - A kind of relieving alcoholism and protecting liver and the Chinese materia medica preparation and preparation method thereof for preventing and treating male sterility - Google Patents
A kind of relieving alcoholism and protecting liver and the Chinese materia medica preparation and preparation method thereof for preventing and treating male sterility Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention discloses a kind of relieving alcoholism and protecting liver and the Chinese materia medica preparation and preparation method thereof of preventing and treating male sterility, the component including following weight parts proportion：Radix Glycyrrhizae：Dry flower of kudzuvine：Pueraria lobata：Contracting fructus amomi：Rhizome of cyrtomium=1：1:1:1:1, preparation method includes：The processes such as weigh, crush, decocting, filtering.Chinese materia medica preparation disclosed by the invention can not only promote the metabolism of liver, protect liver cell, moreover it is possible to caused by preventing and treating because of alcoholism the problem of male sterility.
Description
Technical field
The present invention relates to Chinese medicine preparation technical field, concretely relates to a kind of relieving alcoholism and protecting liver and prevent and treat male sterility
Chinese materia medica preparation and preparation method thereof.
Background technique
Wine has the status that can not be shaken in the long historical progress of the mankind, it be not only meet people's food it
A kind of happy deliciousness, even more a kind of symbol of culture.But some researches show that, the male of long-term alcohol not only sex hormone levels
Low compared with normal male, semen quality is decreased significantly, and because alcohol can to reproduction cell caused by damage, therefore easily cause offspring
Depauperation, abnormal behavior etc..
Although the Chinese materia medica preparation of existing relieving alcoholism and protecting liver can protect liver to a certain extent, effect is not significant, and
And its Chinese materia medica preparation does not play the dependent interaction of protection male reproductive function.
Therefore, how to provide it is a kind of not only can with relieving alcoholism and protecting liver but also can protect male reproductive function Chinese materia medica preparation and its
The problem of preparation method is those skilled in the art's urgent need to resolve.
Summary of the invention
In view of this, the present invention provides a kind of Chinese materia medica preparations and preparation method thereof, both it can protect people's after drinking
Liver, and the symptom because of male reproductive function damage caused by drinking beyond one's capacity can be prevented and treated.
To achieve the goals above, the present invention adopts the following technical scheme that：
A kind of relieving alcoholism and protecting liver and the Chinese materia medica preparation for preventing and treating male sterility, the component including following weight parts proportion：
Radix Glycyrrhizae：Dry flower of kudzuvine：Pueraria lobata：Contracting fructus amomi：Rhizome of cyrtomium=1:1:1:1:1
The preparation method of a kind of relieving alcoholism and protecting liver and the Chinese materia medica preparation for preventing and treating male sterility, is prepared by following step：
1) it weighs：By Radix Glycyrrhizae, dry flower of kudzuvine, pueraria lobata, contracting fructus amomi and rhizome of cyrtomium according to 1:1:1:1:1 ratio is weighed and is mixed
Uniformly, mixed material is obtained；
2) it crushes：Mixed material in the step 1) is placed in grinder, is fully ground to powder, last shape is obtained
Mixture；
3) it decocts：Last shape mixture in the step 2) is placed in decocting machine, the water of 3-5 times of volume, high fire is added
After decocting 20-30min, uses instead and be cooked by slow fire 0.5-1h, obtain decoction liquor；
4) it filters：By the decoction liquor filter and remove residue in the step 3), Chinese materia medica preparation is obtained.
Optionally, the fineness of grind in the step 2) is 100-200 mesh.
Optionally, also the mixed material can be subjected to ultrasonic grind in the step 2).
As can be seen from the above technical solutions, compared with prior art, the effect and collaboration of various traditional Chinese medicinal components in the present invention
The mechanism of action it is as follows：
Pueraria lobata, property is sweet, pungent, cool, return lung, spleen, stomach meridian, and effect energy relieving muscles diaphoresis, promoting eruption, promote the production of body fluid to quench thirst relieving restlessness, and rising Yang stops
It rushes down, sore is treated in promoting blood circulation, is relieved the effect of alcohol.Such as《Qianjin Yao Fang》Juice, which is smash, with fresh pueraria lobata controls the liquor-saturated person that do not wake up.Song Dynasty《Amplification on Materia Medica》Powder is taken with pueraria lobata
Drunken person is controlled, is said:" sick wine and thirsty person, row are good ".The more polydipsia of alcoholic, impairing the spleen and stomach person may occur in which again receive it is poor, vomit
It spits and waits diseases, pueraria lobata energy " main vomiting " (《Sheng Nong's herbal classic》) " whetting the appetite ... stops polydipsia " (《Haigoushen》), therefore to drunk
Person, the benefits of having to the ill.Clinic can also be incorporated the product of spleen benefiting and stimulating the appetite preventing or arresting vomiting,《Drugization justice》Claiming pueraria lobata, " assistant drugs strengthening spleen, is amusing
Power ".Such as Prescriptions for Universal Relief》Flower of kudzuvine ball, pollen end is equal with flower, fructus amomi, (grass) beans model, dark plum to be used, insobriety, vomiter.
《Confucian's Duties to Their Parents》Middle pueraria lobata dissipates, and is shared with it and flower of kudzuvine, fructus amomi etc., is used for insobriety, the person of accumulateing in wine poison.((high precipice honor is raw》
Erchen tang, with same dried orange peel, green peel, adapteds, the main wine such as the tuber of pinellia faints.Ge Hong《101 side afterwards》Take it for main ingredient, to relieve the effect of alcohol,
" controlling drunk deeply day after day tired poison can't bear ".
Flower of kudzuvine, it is sweet, cool, return stomach meridian, activating spleen by relieving alcoholism.It cures mainly and gets sick from drinking too much wine, do not feel like eating.《Mingyi Bielu》Yan Qi:" disappear wine ".
《Compendium of Materia Medica》There is the record of " flower of kudzuvine smell sweetness and bitterness cures mainly and is amusing, controls wine product ".《The southern regions of the Yunnan Province book on Chinese herbal medicine》, call its " activating spleen by relieving alcoholism, wine
Poisonous wine dysentery, diet are not thought, and the glutted hair of septum pectorale oh, vomits sour phlegm, and wine poison injures one's stomach, and haematemesis spitting blood, disappear heat, relieving alcoholism.
Fructus amomi, pungent, warm, returns spleen, stomach, kidney channel, ventilating, stomach strengthening and digestion promoting, dampness elimination of being amusing.Cure mainly stomach abdominal distention and pain, appetite
It is depressed, nausea and vomiting., there are receiving the diseases such as poor, vomiting in alcoholic's injuring spleen-stomach.Therefore supplying contracting fructus amomi is removed dampness by means of aromatics, promoting the circulation of qi
Invigorating the spleen.《Pharmacological property general examination》Cloud its " sobering up ",《Medical center bun is wanted》Say its " and taste, relieving stagnation ".
Rhizome of cyrtomium, it is bitter, cool, enter liver, stomach meridian, heat-clearing, removing toxic substances, cool blood, hemostasis.Anemopyretic cold is cured mainly, macula is warmed, is spitted blood,
Maggot blood, hematochezia, bloody flux, metrorrhagia, leukorrhagia, sore, hematuria, menorrhalgia, knife wound bleeding, roundworm, rich worm, taeniasis, people
Work miscarriage, postpartum haemorrhage.《Prescriptions for Universal Relief》Rhizome of cyrtomium dissipates:Solve all heat toxins or middle food poison, wine poison, poisoning of drug.《This warp》:" main abdomen
It is possessed hot gas, all poison kill three worms ".《The southern regions of the Yunnan Province book on Chinese herbal medicine》:" toxic removing, hemostasis, solution water poison "
Radix Glycyrrhizae, sweet, flat, return heart, lung, spleen, stomach meridian are invigorated the spleen and benefited qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, are reconciled
All medicines.For weakness of the spleen and the stomach, fatigue and weakness, shortness of breath and palpitation, coughing with a lot of sputum, institute's abdomen pain, carbuncle sore tumefacting virus, food poisoning etc..
《The Decoction and Material Medica》" Radix Glycyrrhizae is monarch in all medicines, controls 72 kinds of mammary calculus poison, and vegetation is malicious by every means for solution 1,002, and many medicines that reconcile are active,
Therefore the title for having state old."《It does not record》Speech:" hundred poisoning of druies of solution are the essence of nine soil, peace and 72 kinds of stones, 1,200 kinds of grass ".《This
Sketch warp》Speech " Radix Glycyrrhizae can solve hundred poison, for wanting for many medicines ".
Wine body heat is wet, and smell is all positive, and gas is agile and brave, if drink is improper, comfortable drink is immoderate, easily stagnant in middle coke, checks spleen
Soil influences transporting and transforming function of the spleen and stomach, and internal organs is made to get along well, and trough mutually simultaneously, is unable to distinguish between the clear and the muddy, and strongly fragrant innerization heat, with the passing of time phlegm wet is mutually held under the arm, is hurt in body.
Therefore with Sobering-up Chinese medicine pueraria lobata, flower of kudzuvine activating spleen by relieving alcoholism, influences the absorption of alcohol and promote the metabolism of alcohol by liver protection.Spleen is dry
Dirty, like dryness and hate wetness, damp and hot heresy, which is reluctant to leave, does not go, and hinders the mechanism of qi of spleen, occurs receiving the diseases such as poor, vomiting.Therefore with the property of fructus amomi fragrance
Ventilating, invigorating the spleen for eliminating dampness, stomach function regulating help digestion.It is equipped with its bitter cool property of rhizome of cyrtomium, it is clearing heat and detoxicating etc..Radix Glycyrrhizae nature and flavor belong to sweet returns spleen
Stomach meridian is invigorated the spleen and benefited qi, and pharmacological property, detoxicating functions are mitigated.But it is sugariness, in Gan Kekui, enables swelling of REN ZHONG, and forefathers have sweet slow help
Wet says.《Materia medica》It says:" in full person avoid it is sweet, family of vomitting avoid it is sweet, wineshop avoid it is sweet, this all card should not Radix Glycyrrhizae "《Soup sheet
Grass》Also on the books " over-eating the food with sweet flavor bringing about abdominal distension, in full person eat sweet, sweet slow and Kui gas hurriedly, it is non-in full institute preferably ".Though for the institute of wineshop
Avoid, the wine of side's treatment herein is hurt in card type, and the damp and hot stagnant taste of heresy Kui, taste are tired by damp evil, can not rouse oneself the gas of clear sun, such as
It gives sugariness and mends it, be tantamount to carry faggots to put out a fire, therefore think and play the justice that its removing toxic substances mitigates all medicines in this Radix Glycyrrhizae.All medicine compatibilities, can
Remissive treatment wine wound originally, can also mitigate the mark for eliminating body wine wound, play prevention and treatment insobriety, the function accumulate in wine poison altogether.
Specific embodiment
The following is a clear and complete description of the technical scheme in the embodiments of the invention, it is clear that described implementation
Example is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, this field is general
Logical technical staff every other embodiment obtained without making creative work, belongs to protection of the present invention
Range.
Embodiment one
A kind of relieving alcoholism and protecting liver and the Chinese materia medica preparation for preventing and treating male sterility, the component including following weight parts proportion：
Radix Glycyrrhizae：Dry flower of kudzuvine：Pueraria lobata：Contracting fructus amomi：Rhizome of cyrtomium=1:1:1:1:1.
Pueraria lobata：Property sweet, pungent, cool, return lung, spleen, stomach meridian, can relieving muscles diaphoresis, promoting eruption, promoting the production of body fluid to quench thirst, it is tired to disappear, Shengyang Zhixie,
Sore is treated in promoting blood circulation, is relieved the effect of alcohol；The power of regeneration for improving stem cell restores normal liver function, promotes bile secretion, prevents fat
It is accumulated in liver；And it boosts metabolism, reinforces liver detoxification function, prevent damage of the alcohol to liver；Flower of kudzuvine：Property is sweet,
It is cool, return stomach meridian, activating spleen by relieving alcoholism, dysphoria and thirsty, headache and dizzy, abdominal fullness and distention, inverse acid regurgitation of vomitting after being chiefly used in excessive drinking, no
Think the symptoms such as diet；Contracting fructus amomi：Cure mainly consumptive disease it is cold rush down, place food does not disappear, red white to let out empty pain in benefit and abdomen；Flower of kudzuvine and contracting fructus amomi
Common compatibility can remove dampness by means of aromatics, promoting the circulation of qi invigorating the spleen.Rhizome of cyrtomium：Solve all scorchingly hot or middle food poison, wine poison, poisoning of drug etc.；Radix Glycyrrhizae：It mends
Spleen QI invigorating, relieving spasm to stop pain, coordinating the drug actions of a prescription.
The preparation method of a kind of relieving alcoholism and protecting liver and the Chinese materia medica preparation for preventing and treating male sterility, is prepared by following step：
1) it weighs：By Radix Glycyrrhizae, dry flower of kudzuvine, pueraria lobata, contracting fructus amomi and rhizome of cyrtomium according to 1:1:1:1:1 ratio is weighed and is mixed
Uniformly, mixed material is obtained；
2) it crushes：Mixed material in step 1) is placed in grinder, is fully ground to powder, last shape mixing is obtained
Object；
3) it decocts：Last shape mixture in step 2) is placed in decocting machine, the water of 3-5 times of volume is added, high fire decocts
It after 20-30min, uses instead and is cooked by slow fire 0.5-1h, obtain decoction liquor；
4) it filters：By the decoction liquor filter and remove residue in step 3), Chinese materia medica preparation is obtained.
Optionally, the fineness of grind in step 2) is 100-200 mesh.
Optionally, also mixed material can be subjected to ultrasonic grind in step 2).
Preparation of the invention is taken when taking according to the metering of taking of 0.5-2g crude drug/100g body weight/day.
Embodiment two
The effect of invention formulation is verified in conjunction with the theory of traditional Chinese medicine：
Experimental method：50 Adult SD male rats (210 ± 20g of weight) are randomly divided into 5 groups, normal group, model group,
Low dose group, middle dose group and high dose group, every group 10.Normal group gives physiological saline stomach-filling 1ml/ (100g.d), model
Group gives 60% alcoholic solution stomach-filling 1ml/ (100g.d) with each therapeutic dose group.After 30min, each treatment group is with various dose
Traditional Chinese medicine decoction stomach-filling 1ml/ (100 g.d), the corresponding crude drug amount of low middle high dose group is 0.5g, 1g, 2g/100g
(weight), normal group and model group generation with same amount of normal saline stomach-filling, continuous five weeks.After five weeks, each group rat blood serum is measured
In testosterone (T), lutropin (LH), follicular stimulating hormone (FSH), alpha-glucosidase, acid phosphatase, fruit in refining
Sugar, Zn content, it is as a result as follows：
Conclusion, the Chinese materia medica preparation have apparent treatment to make male rat hypogona dism caused by chronic alcoholism
With.
Each embodiment in this specification is described in a progressive manner, the highlights of each of the examples are with its
The difference of his embodiment, the same or similar parts in each embodiment may refer to each other.For being filled disclosed in embodiment
For setting, since it is corresponded to the methods disclosed in the examples, so being described relatively simple, related place is referring to method portion
It defends oneself bright.
The foregoing description of the disclosed embodiments enables those skilled in the art to implement or use the present invention.
Various modifications to these embodiments will be readily apparent to those skilled in the art, defined herein
General Principle can realize in other embodiments without departing from the spirit or scope of the present invention.Therefore, originally
Invention is not intended to be limited to the embodiments shown herein, and is to fit to special with principles disclosed herein and novelty
The consistent widest scope of point.
Claims (4)
1. a kind of relieving alcoholism and protecting liver and the Chinese materia medica preparation for preventing and treating male sterility, which is characterized in that the group including following weight parts proportion
Point：
Radix Glycyrrhizae：Dry flower of kudzuvine：Pueraria lobata：Contracting fructus amomi：Rhizome of cyrtomium=1:1:1:1:1 .
2. a kind of relieving alcoholism and protecting liver and prevent and treat male sterility Chinese materia medica preparation preparation method, which is characterized in that by following step system
It is standby to form：
1) it weighs：By Radix Glycyrrhizae, dry flower of kudzuvine, pueraria lobata, contracting fructus amomi and rhizome of cyrtomium according to 1:1:1:1:1 ratio is weighed and is uniformly mixed,
Obtain mixed material；
2) it crushes：Mixed material in the step 1) is placed in grinder, is fully ground to powder, last shape mixing is obtained
Object；
3) it decocts：Last shape mixture in the step 2) is placed in decocting machine, the water of 3-5 times of volume is added, high fire decocts
It after 20-30min, uses instead and is cooked by slow fire 0.5-1h, obtain decoction liquor；
4) it filters：By the decoction liquor filter and remove residue in the step 3), Chinese materia medica preparation is obtained.
3. the preparation method of a kind of relieving alcoholism and protecting liver according to claim 2 and the Chinese materia medica preparation for preventing and treating male sterility, special
Sign is that the fineness of grind in the step 2) is 100-200 mesh.
4. the preparation method of a kind of relieving alcoholism and protecting liver according to claim 2 and the Chinese materia medica preparation for preventing and treating male sterility, special
Sign is, also the mixed material can be carried out ultrasonic grind in the step 2).
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109924377A (en) * | 2018-12-07 | 2019-06-25 | 西北农林科技大学 | A kind of liver-protection health-care beverage of Quick sobering and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107184891A (en) * | 2017-05-17 | 2017-09-22 | 安徽新华学院 | A kind of sobering-up composition, preparation method and evaluation method |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107184891A (en) * | 2017-05-17 | 2017-09-22 | 安徽新华学院 | A kind of sobering-up composition, preparation method and evaluation method |
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| Title |
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| 王庆学等: "葛根散对酒伤大鼠血清性激素水平的影响 ", 《贵阳中医学院学报》 * |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109924377A (en) * | 2018-12-07 | 2019-06-25 | 西北农林科技大学 | A kind of liver-protection health-care beverage of Quick sobering and preparation method thereof |
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Application publication date: 20181123 |