CN108815275A - A kind of combination formula and preparation method thereof for gynaecological imflammation - Google Patents

A kind of combination formula and preparation method thereof for gynaecological imflammation Download PDF

Info

Publication number
CN108815275A
CN108815275A CN201810868633.2A CN201810868633A CN108815275A CN 108815275 A CN108815275 A CN 108815275A CN 201810868633 A CN201810868633 A CN 201810868633A CN 108815275 A CN108815275 A CN 108815275A
Authority
CN
China
Prior art keywords
parts
extracting solution
mass
combination formula
mass parts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810868633.2A
Other languages
Chinese (zh)
Inventor
苻史贤
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangzhou Branson Biotechnology Co Ltd
Original Assignee
Guangzhou Branson Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guangzhou Branson Biotechnology Co Ltd filed Critical Guangzhou Branson Biotechnology Co Ltd
Priority to CN201810868633.2A priority Critical patent/CN108815275A/en
Publication of CN108815275A publication Critical patent/CN108815275A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234—Cnidium (snowparsley)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/51—Gentianaceae (Gentian family)
    • A61K36/515—Gentiana
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/756—Phellodendron, e.g. corktree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Urology & Nephrology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The present invention relates to a kind of combination formulas and preparation method thereof for gynaecological imflammation.A kind of combination formula for gynaecological imflammation, according to the mass fraction, total amount are 100 mass parts, including following components：0.15-2 parts of sulphur stoste, 0.1-5 parts of cortex phellodendri extract, 0.5-15 parts of Radix Sophorae Flavescentis extractive liquid, 0.1-3 parts of cortex moutan extracting solution, 0.1-5 parts of frutus cnidii extracting solution, 0.1-5 parts of fruit of summer cypress extracting solution, 0.1-10 parts of radix gentianae extracting solution, deionized water surplus.A kind of preparation method of the combination formula for gynaecological imflammation is used to prepare the combination formula for gynaecological imflammation, includes the following steps：Weigh the sulphur stoste of 0.15-2 mass parts, the cortex phellodendri extract of 0.1-5 mass parts, the Radix Sophorae Flavescentis extractive liquid of 0.5-15 mass parts, the cortex moutan extracting solution of 0.1-3 mass parts, the frutus cnidii extracting solution of 0.1-5 mass parts, the fruit of summer cypress extracting solution of 0.1-5 mass parts and 0.1-10 mass parts radix gentianae extracting solution, total amount is 100 mass parts, and with deionized water complementary amount, said components are mixed evenly, the combination formula for gynaecological imflammation is obtained.

Description

A kind of combination formula and preparation method thereof for gynaecological imflammation
Technical field
The present invention relates to field of pharmaceutical preparations, more particularly to a kind of for the combination formula of gynaecological imflammation and its preparation side Method.
Background technique
Gynaecological imflammation is the common disease of women, is primarily referred to as the inflammation of female sex organ, most common several gynaecology Inflammation is leukorrhagia pruritus vulvae, vulvitis, trichomonas vaginitis, colpomycosis and bacterial vaginitis, and the physiology generated is former Because：
1, female vulva position skin is very delicate, and sweat gland of skin is abundant, and gauffer is more, hidden not expose, poor air permeability, most It is easy to be attacked by germ.
2, the genitals of women, abdominal cavity are communicated with the external world, this is the unique distinction of female sex organs, and germ can be by yin Road enters uterus.
3, under normal conditions, intravaginal has a large amount of Bacillus acidi lactici, it decomposes glycogen and generates lactic acid, makes intravaginal in acidity Environment is unfavorable for the growth of harmful bacteria, but in the decline of local resistance, some germs and pathogen will take advantage of a weak point.
4, introitus and urethral orifice, anus close on, by urine, the pollution of excrement, germ easy to breed.
5, due to menstruation, gestation etc., cervix long period of soaking is in irritating secretion, exuviation, is easy Cause multiple pathogens in endocervix fold and body of gland hiding wherein.
Gynaecological imflammation generate causes for pathological be：
1, menstrual period do not pay attention to health：Use unclean sanitary belt, menstrual period sexual life etc..
2, intrauterine surgical operation disinfection is not tight.
3, the gynecological surgeries such as the stream of people, childbirth cause to damage to uterine neck and vagina, cause infection.
4, female vulva and private parts mucous membrane are the movable vitals of property of participation, and sexual life can generate damage to local organization Or cross-infection.
5, mature women's vaginal pH is weakly acidic, there is inhibition bacterial reproduction to a certain extent, pre- aseptic ability, And the development of youngest daughter's vulva is poor, lacks estrogen, intravaginal pH value is higher, therefore anti-infection ability is poor, is easily infected by bacterial.
Generally speaking, gynaecological imflammation problem is mostly caused by infecting, and to be treated gynaecological imflammation problem and is heat-clearing and damp-drying drug, kills Bacterium, desinsection and antipruritic.
Summary of the invention
Based on this, the object of the present invention is to provide a kind of combination formulas and preparation method thereof for gynaecological imflammation.
A kind of combination formula for gynaecological imflammation of the invention, according to the mass fraction, total amount are 100 mass parts, including Following components：
It is further preferred that the preparation method of the sulphur stoste is：By the sulphur powder of 1 mass parts and 99 mass parts Pure water mixing is fully ground and crosses sieve, obtains the sulphur stoste.
It is further preferred that the cortex phellodendri extract includes following component in parts by mass：
3 parts of phellodendron extract
97 parts of water.
It is further preferred that the Radix Sophorae Flavescentis extractive liquid includes following component in parts by mass：
3 parts of shrubby sophora extract
97 parts of water.
It is further preferred that the cortex moutan extracting solution includes following component in parts by mass：
5 parts of Cortex Moutan extract
95 parts of water.
It is further preferred that the frutus cnidii extracting solution includes following component in parts by mass：
3 parts of common cnidium fruit P.E
97 parts of water.
It is further preferred that the fruit of summer cypress extracting solution includes following component in parts by mass：
5 parts of Fructus Kochiae extract
95 parts of water.
It is further preferred that the radix gentianae extracting solution includes following component in parts by mass：
5 parts of Radix Gentianae extract
95 parts of water.
Combination formula for gynaecological imflammation of the invention can be with heat-clearing and damp-drying drug, quick anti-inflammatory, antibacterial, antipruritic, alleviation yin Portion's inflammatory symptom, while by the trichomonad, mould and killing bacteria in affected part, and inhibit the breeding of trichomonad, mould and bacterium, from basic The upper pathogeny for eliminating trichomonas vaginitis, colpomycosis and bacterial vaginitis, to achieve the effect that sample is part-time.This The combination formula for gynaecological imflammation of invention with ingredient natural, mild muting sensitive, effect it is good, it is without side-effects, easy to use, at This low feature.
The present invention still further provides a kind of preparation method of combination formula for gynaecological imflammation, is used to prepare above-mentioned Described in any item combination formulas for gynaecological imflammation, include the following steps：The sulphur stoste of weighing 0.15-2 mass parts, The cortex phellodendri extract of 0.1-5 mass parts, the Radix Sophorae Flavescentis extractive liquid of 0.5-15 mass parts, 0.1-3 mass parts cortex moutan extracting solution, The radix gentianae of the frutus cnidii extracting solution of 0.1-5 mass parts, the fruit of summer cypress extracting solution of 0.1-5 mass parts and 0.1-10 mass parts is extracted Liquid, total amount is 100 mass parts, and uses deionized water complementary amount, and said components are mixed evenly, and is obtained scorching for gynaecology The combination formula of disease.
Compared with the existing technology, the preparation method preparation process of the combination formula for gynaecological imflammation of the invention it is simple, Component Source is abundant, safe, easy to spread.
Specific embodiment
Embodiment one
The combination formula for gynaecological imflammation of the present embodiment, according to the mass fraction, total amount are 100 mass parts, including with Lower component：
The preparation method of the embodiment of the present invention sulphur stoste is：By the pure of the sulphur powder of 1 mass parts and 99 mass parts Water mixing is fully ground and crosses sieve, obtains the sulphur stoste.
The sulphur stoste has the drug effect of sterilizing and itch-relieving, antibacterial anti-inflammatory, can produce hydrogen sulfide and five with skin contact Thiosulfonic acid plays the role of sterilization, kills scabies, and its aqueous solution is in acidity, close with vagina ph environment, is not destroying vagina ph environment In the case of bactericidal antiphlogistic.
It is further preferred that the cortex phellodendri extract includes following component in parts by mass：
3 parts of phellodendron extract
97 parts of water.
The cortex phellodendri extract has anti-inflammatory effect, can be used for damp-heat dysentery, jaundice and reddish urine, leukorrhagia pruritus vulvae, heat gonorrhea Puckery pain, eczema wet sore.The cortex phellodendri extract is provided by Huzhou Jiamei Biochemical Products Co., Ltd..
It is further preferred that the Radix Sophorae Flavescentis extractive liquid includes following component in parts by mass：
3 parts of shrubby sophora extract
97 parts of water.
The Radix Sophorae Flavescentis extractive liquid has effects that antipyretic, antibacterial, can be used for hot dysentery, hematochezia, jaundice urodialysis, red leukorrhea Under, swelling of vulva pruritus vulvae, eczema, wet sore, pruitus, castor controls trichomonas vaginitis outside.The Radix Sophorae Flavescentis extractive liquid is by Huzhou Biochemistry Products Co., Ltd of Jiamei provides.
It is further preferred that the cortex moutan extracting solution includes following component in parts by mass：
5 parts of Cortex Moutan extract
95 parts of water.
The cortex moutan extracting solution has the effect of antibacterial, anti-inflammatory.The cortex moutan extracting solution is by positive standing grain (Guangzhou) biology Science and Technology Ltd. provides.
It is further preferred that the frutus cnidii extracting solution includes following component in parts by mass：
3 parts of common cnidium fruit P.E
97 parts of water.
The frutus cnidii extracting solution can be with eliminating dampness, wind-dispelling, desinsection, warming kidney and enhancing body.External application can treat eczema of vulva, yin Itch, trichomonas vaginitis etc..The frutus cnidii extracting solution is provided by Huzhou Jiamei Biochemical Products Co., Ltd..
It is further preferred that the fruit of summer cypress extracting solution includes following component in parts by mass：
5 parts of Fructus Kochiae extract
95 parts of water.
The fruit of summer cypress extracting solution has effects that clearing heat and promoting diuresis, dispelling wind and arresting itching, can be used for difficulty and pain in micturition, pruritus vulvae band Under, rubeola, eczema and pruitus etc..The fruit of summer cypress extracting solution is provided by Huzhou Jiamei Biochemical Products Co., Ltd..
It is further preferred that the radix gentianae extracting solution includes following component in parts by mass：
5 parts of Radix Gentianae extract
95 parts of water.
The radix gentianae extracting solution has effects that heat-clearing and damp-drying drug, purging the liver of pathogenic fire gallbladder fire, fire of dispelling determine wind, can be used for damp and hot Huang Subcutaneous ulcer, urine leaching pain, swelling of vulva pruritus vulvae, humid tropics are inferior.The fruit of summer cypress extracting solution is by the limited public affairs of Huzhou Jiamei biochemistry product Department provides.
The preparation method of the combination formula for gynaecological imflammation of the present embodiment, be used to prepare the present embodiment is directed to gynaecology The combination formula of inflammation, includes the following steps：Weigh the sulphur stoste of 0.15 mass parts, the cortex phellodendri extract of 5 mass parts, 0.5 The Radix Sophorae Flavescentis extractive liquid of mass parts, the cortex moutan extracting solution of 3 mass parts, the frutus cnidii extracting solution of 0.1 mass parts, 5 mass parts ground The radix gentianae extracting solution of skin extracting solution and 10 mass parts, total amount are 100 mass parts, and with deionized water complementary amount, will be above-mentioned Component is mixed evenly, and obtains the combination formula for gynaecological imflammation.
In preparation process, gnotobasis should be kept, all tools, vessel all answer strict sterilization.
Embodiment two
The combination formula for gynaecological imflammation of the present embodiment, according to the mass fraction, total amount are 100 mass parts, including with Lower component：
The sulphur stoste of the present embodiment, Radix Sophorae Flavescentis extractive liquid, Radix Sophorae Flavescentis extractive liquid, cortex moutan extracting solution, frutus cnidii extracting solution, Skin extracting solution and radix gentianae extracting solution are identical as embodiment one, just do not remake repeat herein.
The preparation method of the combination formula for gynaecological imflammation of the present embodiment, be used to prepare the present embodiment is directed to gynaecology The combination formula of inflammation, includes the following steps：Weigh the sulphur stoste of 2 mass parts, the cortex phellodendri extract of 0.1 mass parts, 15 matter Measure the Radix Sophorae Flavescentis extractive liquid of part, the cortex moutan extracting solution of 0.1 mass parts, the frutus cnidii extracting solution of 5 mass parts, 0.1 mass parts ground The radix gentianae extracting solution of skin extracting solution and 0.1 mass parts, total amount are 100 mass parts, and with deionized water complementary amount, will be above-mentioned Component is mixed evenly, and obtains the combination formula for gynaecological imflammation.
In preparation process, gnotobasis should be kept, all tools, vessel all answer strict sterilization.
Embodiment three
The combination formula for gynaecological imflammation of the present embodiment, according to the mass fraction, total amount are 100 mass parts, including with Lower component：
The sulphur stoste of the present embodiment, Radix Sophorae Flavescentis extractive liquid, Radix Sophorae Flavescentis extractive liquid, cortex moutan extracting solution, frutus cnidii extracting solution, Skin extracts extracting solution and radix gentianae extracting solution is identical as embodiment one, does not just remake repeat herein.
The preparation method of the combination formula for gynaecological imflammation of the present embodiment, be used to prepare the present embodiment is directed to gynaecology The combination formula of inflammation, includes the following steps：Weigh the sulphur stoste of 0.5 mass parts, the cortex phellodendri extract of 2.4 mass parts, 3.5 The Radix Sophorae Flavescentis extractive liquid of mass parts, the cortex moutan extracting solution of 0.5 mass parts, the frutus cnidii extracting solution of 4.6 mass parts, 0.7 mass parts Fruit of summer cypress extracting solution and 2 mass parts radix gentianae extracting solution, total amount is 100 mass parts, and with deionized water complementary amount, will be upper It states component to be mixed evenly, obtains the combination formula for gynaecological imflammation.
In preparation process, gnotobasis should be kept, all tools, vessel all answer strict sterilization.
Example IV
The combination formula for gynaecological imflammation of the present embodiment, according to the mass fraction, total amount are 100 mass parts, including with Lower component：
The sulphur stoste of the present embodiment, Radix Sophorae Flavescentis extractive liquid, Radix Sophorae Flavescentis extractive liquid, cortex moutan extracting solution, frutus cnidii extracting solution, Skin extracting solution and radix gentianae extracting solution are identical as embodiment one, just do not remake repeat herein.
The preparation method of the combination formula for gynaecological imflammation of the present embodiment, be used to prepare the present embodiment is directed to gynaecology The combination formula of inflammation, includes the following steps：Weigh the sulphur stoste of 0.8 mass parts, the cortex phellodendri extract of 2.0 mass parts, 7 matter Measure the Radix Sophorae Flavescentis extractive liquid of part, the cortex moutan extracting solution of 1.2 mass parts, the frutus cnidii extracting solutions of 3.8 mass parts, 1.4 mass parts The radix gentianae extracting solution of fruit of summer cypress extracting solution and 3.5 mass parts, total amount are 100 mass parts, and with deionized water complementary amount, will be upper It states component to be mixed evenly, obtains the combination formula for gynaecological imflammation.
In preparation process, gnotobasis should be kept, all tools, vessel all answer strict sterilization.
Embodiment five
The combination formula for gynaecological imflammation of the present embodiment, according to the mass fraction, total amount are 100 mass parts, including with Lower component：
The sulphur stoste of the present embodiment, Radix Sophorae Flavescentis extractive liquid, Radix Sophorae Flavescentis extractive liquid, cortex moutan extracting solution, frutus cnidii extracting solution, Skin extracting solution and radix gentianae extracting solution are identical as embodiment one, just do not remake repeat herein.
The preparation method of the combination formula for gynaecological imflammation of the present embodiment, be used to prepare the present embodiment is directed to gynaecology The combination formula of inflammation, includes the following steps：Weigh the sulphur stoste of 1.2 mass parts, the cortex phellodendri extract of 2.5 mass parts, 9.5 The Radix Sophorae Flavescentis extractive liquid of mass parts, the cortex moutan extracting solution of 1.5 mass parts, the frutus cnidii extracting solution of 2.7 mass parts, 2.7 mass parts Fruit of summer cypress extracting solution and 6.5 mass parts radix gentianae extracting solution, total amount be 100 mass parts, and use deionized water complementary amount, general Said components are mixed evenly, and obtain the combination formula for gynaecological imflammation.
In preparation process, gnotobasis should be kept, all tools, vessel all answer strict sterilization.
Embodiment six
The combination formula for gynaecological imflammation of the present embodiment, according to the mass fraction, total amount are 100 mass parts, including with Lower component：
The sulphur stoste of the present embodiment, Radix Sophorae Flavescentis extractive liquid, Radix Sophorae Flavescentis extractive liquid, cortex moutan extracting solution, frutus cnidii extracting solution, Skin extracting solution and radix gentianae extracting solution are identical as embodiment one, just do not remake repeat herein.
The preparation method of the combination formula for gynaecological imflammation of the present embodiment, be used to prepare the present embodiment is directed to gynaecology The combination formula of inflammation, includes the following steps：Weigh the sulphur stoste of 1.52 mass parts, the cortex phellodendri extract of 2.65 mass parts, The Radix Sophorae Flavescentis extractive liquid of 11.5 mass parts, the cortex moutan extracting solution of 2.7 mass parts, the frutus cnidii extracting solution of 3.7 mass parts, 3.45 matter Measure 7.4 mass parts of fruit of summer cypress extracting solution of part and radix gentianae extracting solution, total amount be 100 mass parts, and with deionized water complementary Amount, said components are mixed evenly, the combination formula for gynaecological imflammation is obtained.
In preparation process, gnotobasis should be kept, all tools, vessel all answer strict sterilization.
Embodiment seven
The combination formula for gynaecological imflammation of the present embodiment, according to the mass fraction, total amount are 100 mass parts, including with Lower component：
The sulphur stoste of the present embodiment, Radix Sophorae Flavescentis extractive liquid, Radix Sophorae Flavescentis extractive liquid, cortex moutan extracting solution, frutus cnidii extracting solution, Skin extracting solution and radix gentianae extracting solution are identical as embodiment one, just do not remake repeat herein.
The preparation method of the combination formula for gynaecological imflammation of the present embodiment, be used to prepare the present embodiment is directed to gynaecology The combination formula of inflammation, includes the following steps：Weigh the sulphur stoste of 1.72 mass parts, the cortex phellodendri extract of 2.8 mass parts, The Radix Sophorae Flavescentis extractive liquid of 13.4 mass parts, the cortex moutan extracting solution of 2.4 mass parts, the frutus cnidii extracting solution of 4.7 mass parts, 4.46 matter The fruit of summer cypress extracting solution of part and the radix gentianae extracting solution of 8.6 mass parts are measured, total amount is 100 mass parts, and with deionized water complementary Amount, said components are mixed evenly, the combination formula for gynaecological imflammation is obtained.
In preparation process, gnotobasis should be kept, all tools, vessel all answer strict sterilization.
Embodiment eight
The combination formula for gynaecological imflammation of the present embodiment, according to the mass fraction, total amount are 100 mass parts, including with Lower component：
The sulphur stoste of the present embodiment, Radix Sophorae Flavescentis extractive liquid, Radix Sophorae Flavescentis extractive liquid, cortex moutan extracting solution, frutus cnidii extracting solution, Skin extracting solution and radix gentianae extracting solution are identical as embodiment one, just do not remake repeat herein.
The preparation method of the combination formula for gynaecological imflammation of the present embodiment, be used to prepare the present embodiment is directed to gynaecology The combination formula of inflammation, includes the following steps：Weigh the sulphur stoste of 1.87 mass parts, the cortex phellodendri extract of 2.5 mass parts, The Radix Sophorae Flavescentis extractive liquid of 14.5 mass parts, the cortex moutan extracting solution of 2.9 mass parts, the frutus cnidii extracting solution of 4.35 mass parts, 4.9 matter The fruit of summer cypress extracting solution of part and the radix gentianae extracting solution of 9.2 mass parts are measured, total amount is 100 mass parts, and with deionized water complementary Amount, said components are mixed evenly, the combination formula for gynaecological imflammation is obtained.
In preparation process, gnotobasis should be kept, all tools, vessel all answer strict sterilization.
Compared with the existing technology, the preparation method preparation process of the combination formula for gynaecological imflammation of the invention it is simple, Component Source is abundant, safe, easy to spread.
Combination formula for gynaecological imflammation of the invention is mainly used for leukorrhagia pruritus vulvae, vulvitis, trichomonas vaginitis, mould The gynecological diseases such as bacterium property vaginitis and bacterial vaginitis, dosage form be solution, can direct external application, addition in other formulas also It can reach therapeutic effect, component has effects that strengthen the body resistance to consolidate the constitution, sterilization and disinsection is antipruritic, clearing heat and promoting diuresis, dispels pathogenic wind and remove dampness, and it has Have the characteristics that natural ingredient, mild muting sensitive, effect are good, without side-effects, easy to use, at low cost.
For leukorrhagia pruritus vulvae and vulvitis, the combination formula for gynaecological imflammation of the invention can quickly anti-inflammatory, it is antibacterial, It is antipruritic, alleviate pudendal infection symptom, continuous use can be cured thoroughly.
For trichomonas vaginitis, colpomycosis and bacterial vaginitis, the group for gynaecological imflammation of the invention Closing formula can be by the trichomonad, mould and killing bacteria in affected part, and inhibits the breeding of trichomonad, mould and bacterium, fundamentally disappears Except the pathogeny of trichomonas vaginitis, colpomycosis and bacterial vaginitis, in addition, its inflammation that can also alleviate private parts, clear Hot dampness removing, dispelling wind and arresting itching, restore the normal physiological function in affected part, to achieve the effect that sample is part-time.
In order to prove that the therapeutic effect of the combination formula for gynaecological imflammation of the invention, clinic have chosen 80 through training Patient diagnosis is the patient of gynaecological imflammation, and the age distribution of 80 patients included in this 80 gynaecological imflammation patients at 25-45 years old 16 leukorrhagia pruritus vulvae patients, 16 vulvitis patients, 16 trichomonas vaginitis patients, 16 colpomycosis patients and 16 Name bacterial vaginitis patient, and these patients are divided into 1-8 test group, each test group include 2 leukorrhagia pruritus vulvae patients, 2 vulvitis patients, 2 trichomonas vaginitis patients, 2 colpomycosis patients and 2 bacterial vaginitis patients.It is real The combination formula for gynaecological imflammation for applying example one to eight is orderly used to the patient of 1-8 test group respectively.
Test method：1 is rinsed to vagina and vulva using the combination formula for gynaecological imflammation of the invention sooner or later daily It is secondary, it avoids using during physiology.All other drug that may affect the treatment is deactivated during test, keeps good daily life system And eating habit.
Treatment standard：(1) it fully recovers：Resolution of symptoms, it is salubrious comfortable, it there are no new symptom and occur；(2) effectively：Resolution of symptoms 20-40% or more has no that new symptom occurs；(3) invalid：It does not improve.
Test result：
The test group 1 that embodiment one is treated：
1 leukorrhagia pruritus vulvae patient, 2 vulvitis patients, 2 trichomonas vaginitis patients, 1 colpomycosis patient Be recovery from illness with 1 bacterial vaginitis patient, 1 leukorrhagia pruritus vulvae patient and 1 colpomycosis patient be it is effective, 1 is carefully Bacterium property vaginitis patient is invalid.
The test group 2 that embodiment two is treated：
2 leukorrhagia pruritus vulvae patients, 2 vulvitis patients, 1 trichomonas vaginitis patient, 2 colpomycosis patients It is recovery from illness with 1 bacterial vaginitis patient, 1 trichomonas vaginitis patient and 1 bacterial vaginitis patient are effective.
The test group 3 that embodiment three is treated：
2 leukorrhagia pruritus vulvae patients, 1 vulvitis patient, 2 trichomonas vaginitis patients, 2 colpomycosis patients It is recovery from illness with 2 bacterial vaginitis patients, 1 vulvitis patient is effective.
The test group 4 of example IV treatment：
2 leukorrhagia pruritus vulvae patients, 2 vulvitis patients, 1 trichomonas vaginitis patient, 2 colpomycosis patients It is recovery from illness with 2 bacterial vaginitis patients, 1 trichomonas vaginitis patient is effective.
The test group 5 that embodiment five is treated：
2 leukorrhagia pruritus vulvae patients, 2 vulvitis patients, 2 trichomonas vaginitis patients, 2 colpomycosis patients It is recovery from illness with 1 bacterial vaginitis patient, 1 bacterial vaginitis patient is effective.
The test group 6 that embodiment six is treated：
2 leukorrhagia pruritus vulvae patients, 2 vulvitis patients, 2 trichomonas vaginitis patients, 2 colpomycosis patients It is recovery from illness with 2 bacterial vaginitis patients.
The test group 7 that embodiment seven is treated：
1 leukorrhagia pruritus vulvae patient, 2 vulvitis patients, 2 trichomonas vaginitis patients, 2 colpomycosis patients It is recovery from illness with 2 bacterial vaginitis patients, 1 leukorrhagia pruritus vulvae patient is effective.
The test group 8 that embodiment eight is treated：
2 leukorrhagia pruritus vulvae patients, 2 vulvitis patients, 1 trichomonas vaginitis patient, 2 colpomycosis patients It is recovery from illness with 2 bacterial vaginitis patients, 1 trichomonas vaginitis patient is effective.
For the gynaecological imflammation patient of 1-8 test group during treatment, test result is recovery from illness and effective patient mostly on 5 days left sides The right side is taken effect, and during which has no other side effects or discomfort, though test result is that 1 invalid patient is not cured, is also had no Exacerbation of symptoms illustrates that the combination formula for gynaecological imflammation of the invention is safe.
The therapeutic effect of the combination formula for gynaecological imflammation of embodiment six is best, is most preferred embodiment.
In order to further examine embodiment six the combination formula for gynaecological imflammation therapeutic effect, also clinic have chosen 300 patients for being diagnosed as gynaecological imflammation through special outpatient clinic treat, the age distribution of 300 patients at 23-48 years old, In, have in 300 gynaecological imflammation patients 90 leukorrhagia pruritus vulvae patients, 76 vulvitis patients, 49 trichomonas vaginitis patients, 37 colpomycosis patients and 48 bacterial vaginitis patients.Test method is identical as above-mentioned test method.
Test result：
It fully recovers 270 in 300 gynaecological imflammation patients, effective 29, invalid 1, effective percentage reaches 99.7%, passes through Solution, invalid 1 is recurrent colpomycosis patient.Wherein, efficient=(recovery from illness example+effective example)/total number of cases.
From above-mentioned test result twice it is found that the combination formula for gynaecological imflammation of the invention under treatment zone pruritus vulvae, Apparent treatment effect is achieved on the gynaecological imflammations such as vulvitis, trichomonas vaginitis, colpomycosis and bacterial vaginitis Fruit, the therapeutic agent for being suitable as gynaecological imflammation are promoted.
Combination formula for gynaecological imflammation of the invention can be with heat-clearing and damp-drying drug, quick anti-inflammatory, antibacterial, antipruritic, alleviation yin Portion's inflammatory symptom, while by the trichomonad, mould and killing bacteria in affected part, and inhibit the breeding of trichomonad, mould and bacterium, from basic The upper pathogeny for eliminating trichomonas vaginitis, colpomycosis and bacterial vaginitis, to achieve the effect that sample is part-time.This The combination formula for gynaecological imflammation of invention with ingredient natural, mild muting sensitive, effect it is good, it is without side-effects, easy to use, at This low feature.
It should be pointed out that the combination formula for gynaecological imflammation of the invention is not limited only to using sulphur stoste, Cortex Phellodendri Extracting solution, Radix Sophorae Flavescentis extractive liquid, cortex moutan extracting solution, frutus cnidii extracting solution, fruit of summer cypress extracting solution and radix gentianae extracting solution, other benefits It also can be used as component with sulphur, Cortex Phellodendri, kuh-seng, cortex moutan, frutus cnidii, the fruit of summer cypress and the tanning of radix gentianae product or infusion etc. Source.
The embodiments described above only express several embodiments of the present invention, and the description thereof is more specific and detailed, but simultaneously It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to protection of the invention Range.

Claims (9)

1. a kind of combination formula for gynaecological imflammation, according to the mass fraction, total amount are 100 mass parts, including following components：
2. the combination formula according to claim 1 for gynaecological imflammation, which is characterized in that the preparation of the sulphur stoste Method is：The sulphur powder of 1 mass parts is mixed with the pure water of 99 mass parts, is fully ground and crosses sieve, obtain the sulphur Stoste.
3. the combination formula according to claim 1 for gynaecological imflammation, which is characterized in that the cortex phellodendri extract includes Following component in parts by mass：
3 parts of phellodendron extract
97 parts of water.
4. the combination formula according to claim 1 for gynaecological imflammation, which is characterized in that the Radix Sophorae Flavescentis extractive liquid includes Following component in parts by mass：
3 parts of shrubby sophora extract
97 parts of water.
5. the combination formula according to claim 1 for gynaecological imflammation, which is characterized in that the cortex moutan extracting solution packet Include following component in parts by mass：
5 parts of Cortex Moutan extract
95 parts of water.
6. the combination formula according to claim 1 for gynaecological imflammation, which is characterized in that the frutus cnidii extracting solution packet Include following component in parts by mass：
3 parts of common cnidium fruit P.E
97 parts of water.
7. the combination formula according to claim 1 for gynaecological imflammation, which is characterized in that the fruit of summer cypress extracting solution packet Include following component in parts by mass：
5 parts of Fructus Kochiae extract
95 parts of water.
8. the combination formula according to claim 1 for gynaecological imflammation, which is characterized in that the radix gentianae extracting solution packet Include following component in parts by mass：
5 parts of Radix Gentianae extract
95 parts of water.
9. a kind of preparation method of the combination formula for gynaecological imflammation, is used to prepare the described in any item needles of claim 1-8 To the combination formula of gynaecological imflammation, include the following steps：Weigh the sulphur stoste of 0.15-2 mass parts, the Huang of 0.1-5 mass parts Cypress extracting solution, the Radix Sophorae Flavescentis extractive liquid of 0.5-15 mass parts, the cortex moutan extracting solution of 0.1-3 mass parts, 0.1-5 mass parts cnidium monnieri The radix gentianae extracting solution of sub- extracting solution, the fruit of summer cypress extracting solution of 0.1-5 mass parts and 0.1-10 mass parts, total amount are 100 mass Part, and with deionized water complementary amount, said components are mixed evenly, the combination formula for gynaecological imflammation is obtained.
CN201810868633.2A 2018-08-02 2018-08-02 A kind of combination formula and preparation method thereof for gynaecological imflammation Pending CN108815275A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810868633.2A CN108815275A (en) 2018-08-02 2018-08-02 A kind of combination formula and preparation method thereof for gynaecological imflammation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810868633.2A CN108815275A (en) 2018-08-02 2018-08-02 A kind of combination formula and preparation method thereof for gynaecological imflammation

Publications (1)

Publication Number Publication Date
CN108815275A true CN108815275A (en) 2018-11-16

Family

ID=64152546

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201810868633.2A Pending CN108815275A (en) 2018-08-02 2018-08-02 A kind of combination formula and preparation method thereof for gynaecological imflammation

Country Status (1)

Country Link
CN (1) CN108815275A (en)

Similar Documents

Publication Publication Date Title
CN103272153B (en) Antibacterial gel and preparation method thereof
CN102697961B (en) Gynecological cleaning solution and preparation method thereof
CN103316261B (en) Medical antibacterial liquid and preparation method thereof
CN103721131A (en) Traditional Chinese medicinal suppository for treating female chronic pelvic inflammation and preparation method thereof
CN103316262B (en) A kind of gynecological external antibacterial liquid and preparation method thereof
CN101361937A (en) Medicinal pad with antibiosis, itching-relieving, wind-dispelling and dampness-eliminating function
CN1080971A (en) A kind of antibiotic, fabric and its production and application of sterilizing
CN112294886A (en) Foam type lavender antibacterial lotion and preparation method thereof
CN103751532B (en) A kind of Chinese medicine composition treating gynaecological imflammation and preparation method thereof
CN104771671A (en) Traditional Chinese medicine lotion for treating gynecological inflammation
CN103127312A (en) External Antiviral and anti-pathogenic gynecological lotion and preparation technology
CN110393768A (en) A kind of combined traditional Chinese medicine dabbling drug of Gilt Uterus anti-inflammatory and its preparation method and application
CN102727824B (en) Traditional Chinese medicine used for treating pudendal inflammatory diseases
CN101780172A (en) Bacteriostatic washing liquor with high bacteriostatic action and method for preparing same
CN105267472A (en) Traditional Chinese medicine medicament for treating gynecological diseases and applications thereof
CN108815275A (en) A kind of combination formula and preparation method thereof for gynaecological imflammation
CN103877452B (en) A kind of chitosan vaginal washing fluid and preparation method thereof
CN103920073A (en) Chitosan genital tract biological antibacterial liquid and preparation method thereof
CN103599437B (en) One treats colpitic traditional Chinese medicine liquid
CN103585321B (en) Externally used traditional Chinese medicine composition for treating trichomonas vaginitis
CN102078546A (en) Gynecological medical lotion for external use
CN105998974A (en) Traditional Chinese medicine composition and gels for treating gynecologic inflammation and preparation method thereof
CN102949467A (en) Medicinal composition for treating chronic pelvic inflammation caused by dampness and hotness obstruction
CN111743982A (en) Vulva lotion and preparation method thereof
CN108853410A (en) A kind of Chinese drugs agentia and its preparation method and application for preventing and treating gynecological disease

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20181116