CN108802413A - Quantitative in vitro detecting instrument - Google Patents

Quantitative in vitro detecting instrument Download PDF

Info

Publication number
CN108802413A
CN108802413A CN201811094529.9A CN201811094529A CN108802413A CN 108802413 A CN108802413 A CN 108802413A CN 201811094529 A CN201811094529 A CN 201811094529A CN 108802413 A CN108802413 A CN 108802413A
Authority
CN
China
Prior art keywords
drive component
sample
quantitative
kit
component
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811094529.9A
Other languages
Chinese (zh)
Inventor
尹凌志
陈维森
贾庆祝
赵以龙
许德晨
孙家振
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ji Dan Biotech Inc
Original Assignee
Ji Dan Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ji Dan Biotech Inc filed Critical Ji Dan Biotech Inc
Priority to CN201811094529.9A priority Critical patent/CN108802413A/en
Publication of CN108802413A publication Critical patent/CN108802413A/en
Priority to DE212019000092.4U priority patent/DE212019000092U1/en
Priority to PCT/CN2019/091430 priority patent/WO2020057195A1/en
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0099Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465Separating and mixing arrangements

Abstract

The present invention relates to outer quantitative detection fields, in particular to a kind of Quantitative in vitro detecting instrument.The instrument includes sample sampling device, shake up hood-opening device, kit conveyer, incubation, detection components and mechanical arm.Shake up hood-opening device close to sample sampling device be arranged, shake up hood-opening device for sample sampling device transport come sample tube uncap shake up pass lid.Kit conveyer includes multiple kit storage assemblies and kit conveying mechanism.Mechanical arm is connected with aspirating needle group, and aspirating needle group can be transported to sample sampling device, kit conveyer and incubation, detection components by mechanical arm.Shaking up hood-opening device by setting enables entire Quantitative in vitro detecting instrument automatic lid closing/opening to cover and shake up, and manually need not carry out shaking up and pull out lid, improve the degree of automation.Make sample tube automatic sampling, sample-adding, detection by the way that sample sampling device, kit conveyer and mechanical arm is arranged.

Description

Quantitative in vitro detecting instrument
Technical field
The present invention relates to outer quantitative detection fields, in particular to a kind of Quantitative in vitro detecting instrument.
Background technology
Quantitative in vitro detecting instrument can quantify detection human serum, blood plasma, whole blood or urine.For clinical assistant diagnosis.
Quantitative in vitro detecting instrument test tube in the prior art pulls out lid, machine dimensions without artificial shake up of needs of uncapping is shaken up Preponderance bigger than normal.
Invention content
The purpose of the present invention is to provide a kind of Quantitative in vitro detecting instruments, manually need not uncap shaking up to test tube Covering, high degree of automation.
To achieve the goals above, technical solution used in the embodiment of the present invention is as follows:
A kind of Quantitative in vitro detecting instrument, including:Sample sampling device, sample sampling device place sample examination for conveying The rack for test tube of pipe;Hood-opening device is shaken up, hood-opening device is shaken up and is arranged close to sample sampling device, shakes up hood-opening device for sample The sample tube that the transport of this sampling device comes, which uncap, shakes up pass lid;Kit conveyer, kit conveyer include Multiple kit storage assemblies and kit conveying mechanism;It incubates, detection components;And mechanical arm, mechanical arm are connected with suction Aspirating needle group can be transported to sample sampling device, kit conveyer and incubation, detection group by liquid needle group, mechanical arm Part.
In preferred embodiments of the present invention, shaking up hood-opening device includes:Support portion;Cap-opening mechanism, cap-opening mechanism connection In the side of support portion;Cap-opening mechanism includes uncap clamping jaw, the first drive component, the second drive component and third driving group Part;First drive component, the second drive component and third drive component are sequentially connected in clamping jaw of uncapping;First drive component For driving clamping jaw of uncapping to clamp or release sample tube lid;Second drive component is for driving clamping jaw rotation of uncapping;Third Drive component is for driving clamping jaw of uncapping to move up and down with respect to support portion;Uniform shaking mechanism, uniform shaking mechanism are connected to the another of support portion Side;Uniform shaking mechanism includes clamp assemblies, the 4th drive component, the 5th drive component and the 6th drive component;4th driving Component, the 5th drive component and the 6th drive component are sequentially connected in clamp assemblies;Clamp assemblies are for being clamped sample examination Pipe;4th drive component is for driving clamp assemblies rotation to drive sample tube to rock;5th drive component is pressed from both sides for driving Hold component close to or far from the 4th drive component;6th drive component is for driving clamp assemblies to move up and down;And it is fixed Test tube mechanism, fixed test tube mechanism are arranged below clamping jaw of uncapping, are uncapped for fixed sample test tube with matching closing and opening cover during booting clamping jaw.
In preferred embodiments of the present invention, clamping jaw of uncapping includes at least three holding dogs;The output shaft of first drive component It is connected at least three inclined-planes;The connecting pin of at least three holding dogs is both provided with the skewed slot that connection is matched with inclined-plane;When the first drive When dynamic component movement, at least three holding dogs are driven to be slided along inclined-plane, so that at least three holding dogs are close to each other or separate.
In preferred embodiments of the present invention, clamp assemblies include wobble-member, the first clamping part and the second clamping part;It waves Part is connected to the first clamping part;Second clamping part is sequentially connected in the 5th drive component;First clamping part and the second clamping part phase To setting.
In preferred embodiments of the present invention, the first clamping part is fixedly connected on the 4th drive component, when the 4th driving group Part drives the first clamping part to move when moving, so that the first clamping part is close or far from the second clamping part.
In preferred embodiments of the present invention, kit storage assembly include it is multiple for store the accommodating cavity of kit with And cartridge clip shell;Cartridge clip shell there are one being placed in each accommodating cavity;Multiple kits overlay in cartridge clip shell.
In preferred embodiments of the present invention, kit conveying mechanism includes gripper assembly, moving track and driving group Part;Gripper assembly is used to take out kit from cartridge clip shell inner clip;Gripper assembly is sequentially connected in drive component, to drive folder Component is taken to be moved along moving track.
In preferred embodiments of the present invention, sample sampling device includes driving portion, moving guide rail and multiple for putting Set the support plate of rack for test tube;Driving portion is sequentially connected in moving guide rail;Each support plate is all connected to moving guide rail.
In preferred embodiments of the present invention, sample sampling device further includes barcode scanning component, and barcode scanning component is close to be shaken up out Lid arrangement is arranged;Barcode scanning component is used to carry out barcode scanning to the sample information in rack for test tube.
In preferred embodiments of the present invention, Quantitative in vitro detecting instrument further includes shell, and shell has first end and phase To second end;The setting of sample sampling device incubates component and detection components setting in second end, mechanical arm setting in first end Between the first end and a second end.
The beneficial effects of the invention are as follows:
A kind of Quantitative in vitro detecting instrument provided by the invention, including:Sample sampling device shakes up hood-opening device, reagent Box conveyer, incubation, detection components and mechanical arm.Wherein, sample sampling device is used to convey the examination for placing sample tube Pipe support.It shakes up hood-opening device close to sample sampling device to be arranged, shakes up what hood-opening device was used to transport to come to sample sampling device Sample tube, which uncap, shakes up pass lid.Kit conveyer includes multiple kit storage assemblies and kit conveyer Structure.Mechanical arm is connected with aspirating needle group, and aspirating needle group can be transported to sample sampling device, kit conveyer by mechanical arm And it incubates, detection components.The Quantitative in vitro detecting instrument shakes up hood-opening device by setting and entire Quantitative in vitro is detected Instrument can automatic lid closing/opening covering and shake up, manually need not carry out shaking up and pull out lid, improve the degree of automation.Further Ground realizes sample tube automatic sampling, reagent by the way that sample sampling device, kit conveyer and mechanical arm is arranged Box automatic transportation, automatic sample, automatic detection, improve the degree of automation of entire Quantitative in vitro detecting instrument.
Description of the drawings
In order to illustrate the technical solution of the embodiments of the present invention more clearly, below will be to needed in the embodiment attached Figure is briefly described, it should be understood that the following drawings illustrates only certain embodiments of the present invention, therefore is not construed as pair The restriction of range for those of ordinary skill in the art without creative efforts, can also be according to this A little attached drawings obtain other relevant attached drawings.
Fig. 1 is the structural schematic diagram at the first visual angle of the Quantitative in vitro detecting instrument that first embodiment of the invention provides;
Fig. 2 is the structural schematic diagram at the second visual angle of the Quantitative in vitro detecting instrument that first embodiment of the invention provides;
Fig. 3 is the first visual angle for shaking up hood-opening device for the Quantitative in vitro detecting instrument that first embodiment of the invention provides Structural schematic diagram;
Fig. 4 is the second visual angle for shaking up hood-opening device for the Quantitative in vitro detecting instrument that first embodiment of the invention provides Structural schematic diagram;
Fig. 5 is the third visual angle for shaking up hood-opening device for the Quantitative in vitro detecting instrument that first embodiment of the invention provides Structural schematic diagram;
Fig. 6 is the structural schematic diagram of the clamping jaw of uncapping for the Quantitative in vitro detecting instrument that first embodiment of the invention provides;
Fig. 7 is the structural representation of the kit conveyer for the Quantitative in vitro detecting instrument that first embodiment of the invention provides Figure;
Fig. 8 is the structural representation of the kit conveying mechanism for the Quantitative in vitro detecting instrument that first embodiment of the invention provides Figure;
Fig. 9 is the structural schematic diagram of the cartridge clip shell for the Quantitative in vitro detecting instrument that first embodiment of the invention provides.
Icon:10- Quantitative in vitro detecting instruments;100- sample sampling devices;The areas 101- Xi Yang;The sample application zones 102-;110- Driving portion;120- moving guide rails;130- support plates;140- barcode scanning components;200- shakes up hood-opening device;210- support portions;211- First support plate;The second support plates of 212-;220- cap-opening mechanisms;221- uncaps clamping jaw;The first drive components of 222-;2211- is oblique Face;2212- skewed slots;2221- interconnecting pieces;The second drive components of 223-;2231- driving portions;2232- synchronous belt components;225- Three drive components;230- uniform shaking mechanisms;231- clamp assemblies;2311- wobble-members;The first clamping parts of 2312-;2313- second is pressed from both sides Hold portion;2314- connecting plates;The 4th drive components of 232-;The 5th drive components of 233-;The 6th drive components of 234-;240- is fixed Test tube mechanism;241- fixing pieces;242- actuators;300- kit conveyers;310- kit storage assemblies;311- is accommodating Chamber;312- cartridge clip shells;313- kits;320- kit conveying mechanisms;321- gripper assemblies;322- moving tracks;323- Drive component;400- incubations, detection components;500- mechanical arms;600- shells;610- first ends;620- second ends.
Specific implementation mode
In order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below in conjunction with the embodiment of the present invention In attached drawing, technical scheme in the embodiment of the invention is clearly and completely described, it is clear that described embodiment is A part of the embodiment of the present invention, instead of all the embodiments.The present invention being usually described and illustrated herein in the accompanying drawings is implemented The component of example can be arranged and be designed with a variety of different configurations.
Therefore, below the detailed description of the embodiment of the present invention to providing in the accompanying drawings be not intended to limit it is claimed The scope of the present invention, but be merely representative of the present invention selected embodiment.Based on the embodiments of the present invention, this field is common The every other embodiment that technical staff is obtained without creative efforts belongs to the model that the present invention protects It encloses.
It should be noted that:Similar label and letter indicate similar terms in following attached drawing, therefore, once a certain Xiang Yi It is defined, then it further need not be defined and explained in subsequent attached drawing in a attached drawing.
In the description of the embodiment of the present invention, it should be noted that the orientation of the instructions such as term "upper", "inner" or position are closed System for be based on the orientation or positional relationship shown in the drawings or the invention product using when the orientation usually put or position close System, is merely for convenience of description of the present invention and simplification of the description, not indicating or implying the indicated device or element must have Specific orientation, with specific azimuth configuration and operation, therefore be not considered as limiting the invention.
In the description of the present invention, it is also necessary to which explanation is unless specifically defined or limited otherwise, term " setting ", " installation ", " connected ", " connection " shall be understood in a broad sense, for example, it may be fixedly connected, may be a detachable connection or one Connect to body;It can be directly connected, can also can be indirectly connected through an intermediary the connection inside two elements. For the ordinary skill in the art, the concrete meaning of above-mentioned term in the present invention can be understood with concrete condition.
First embodiment
Fig. 1-Fig. 9 is please referred to, the present embodiment provides a kind of Quantitative in vitro detecting instruments 10 comprising sample sampling device 100, hood-opening device 200, kit conveyer 300, incubation, detection components 400, mechanical arm 500 and shell 600 are shaken up. The Quantitative in vitro detecting instrument 10 shakes up hood-opening device 200 by setting and enables entire Quantitative in vitro detecting instrument 10 automatic It uncaps and covers and shake up, manually need not carry out shaking up and pull out lid, improve the degree of automation.Further, by the way that sample is arranged This sampling device 100, kit conveyer 300 and mechanical arm 500 realize kit so that sample tube automatic sampling Automatic transportation, automatic TIP sample-addings are automatic to detect, and improve the degree of automation of entire Quantitative in vitro detecting instrument 10.
Further, kit conveyer 300, incubation, detection components 400 and mechanical arm 500 are arranged at shell In 600.Further, shell 600 has first end 610 and opposite second end 620;The setting of sample sampling device 100 is the One end 610, incubates, the setting of detection components 400 is in second end 620, the setting of mechanical arm 500 first end 610 and second end 620 it Between.Further, it shakes up the setting of hood-opening device 200 in shell 600 to expose to first end 610, to fill with sample sample introduction 100 mutual cooperations are set, to sample tube uncap shakes up pass lid.Further, mechanical arm 500 is arranged in 610 He of first end It is convenient to be run between sample sampling device 100, incubation component and detection components between second end 620.Specifically, mechanical Arm 500 is connected with aspirating needle group, and aspirating needle group can be transported to sample sampling device 100 by mechanical arm 500, kit transports dress It sets 300 and incubates, detection components 400.The 10 sample sampling device 100 of Quantitative in vitro detecting instrument shakes up hood-opening device 200, kit conveyer 300, incubation, detection components 400 and 500 each testing process of mechanical arm are rationally distributed, operation Reliably, compact-sized, reduce the volume of entire Quantitative in vitro detecting instrument 10.
It should be noted that above-mentioned incubation, detection components 400 can select this field it is common be suitable for fluoroscopic examination Structure.
Further, sample sampling device 100 is used to convey the rack for test tube for placing sample tube.Specifically, sample sample introduction Device 100 includes driving portion 110, moving guide rail 120 and multiple support plates 130 for holding test tubes frame;Driving portion 110 passes It is dynamic to be connected to moving guide rail 120;Each support plate 130 is all connected to moving guide rail 120.
Further, sample sampling device 100 further includes barcode scanning component 140, and barcode scanning component 140 is close to shake up hood-opening device 200 settings;Barcode scanning component 140 is used to carry out barcode scanning to the sample information in rack for test tube.
Further, shake up hood-opening device 200 close to sample sampling device 100 be arranged, shake up hood-opening device 200 for pair The sample tube that the transport of sample sampling device 100 comes, which uncap, shakes up pass lid.
Specifically, it includes support portion 210, cap-opening mechanism 220, uniform shaking mechanism 230 and fixed examination to shake up hood-opening device 200 Pipe mechanism 240.
Further, cap-opening mechanism 220 is connected to the side of support portion 210, and uniform shaking mechanism 230 is connected to support portion 210 The other side so that uncapping and shake up operation will not interfere with each other, can carry out successively.Cap-opening mechanism 220 and uniform shaking mechanism 230 rational and compacts, further such that the small volume of entire Quantitative in vitro detecting instrument 10, has the characteristics that miniaturization.
Further, support portion 210 includes the first support plate 211 and the second support plate 212.First support plate 211 and Two support plates 212 are oppositely arranged.Cap-opening mechanism 220 is connected to the side of the first support plate 211, and uniform shaking mechanism 230 is connected to The other side of one support plate 211, to separate cap-opening mechanism 220 and uniform shaking mechanism 230.Further, the second support plate 212 are arranged in side of the cap-opening mechanism 220 far from the first support plate 211, further increase and entirely shake up hood-opening device 200 Integral rigidity, and then can ensure to shake up, the stationarity for movement of uncapping.
Further, cap-opening mechanism 220 include uncap clamping jaw 221, the first drive component 222, the second drive component 223 with And third drive component 225.First drive component 222, the second drive component 223 and third the drive component 225 company of transmission It is connected to clamping jaw 221 of uncapping.First drive component 222 is for driving clamping jaw 221 of uncapping to clamp or release sample tube lid;Second Drive component 223 is for driving the rotation of clamping jaw 221 of uncapping;Third drive component 225 is for driving about 221 clamping jaw fortune of uncapping It is dynamic.So that clamping jaw 221 of uncapping clamps sample tube lid while rotating, and moves up and down and realize mould human hand twist-off closure Action, and then sample tube lid is opened or is closed the lid for sample tube.
Further, clamping jaw 221 of uncapping includes at least three holding dogs.The output shaft of first drive component 222 be provided with to Few three inclined-planes 2211;The connecting pin of at least three holding dogs is both provided with the skewed slot 2212 that connection is matched with inclined-plane 2211.When One drive component 222 move when, drive at least three holding dogs along inclined-plane 2211 slide so that at least three holding dogs it is close to each other or Person is separate.
Specifically, there are interconnecting piece 2221, at least three inclined-planes in the end set of the output shaft of the first drive component 222 2211 are connected to interconnecting piece 2221.In the present embodiment, the first drive component 222 is linear motor, when linear motor moves, The sliding in three skewed slots 2212 above-mentioned of three inclined-planes 2211 is driven, so that three holding dogs are located remotely from each other or mutually lean on Closely.When needing to open bottle cap, three holding dogs are close to each other, promptly sample tube.Further, on the inner wall of each holding dog Multiple friction portions are both provided with, and then can firmly firmly grasp sample tube.
Further, the second drive component 223 includes driving portion 2231 and synchronous belt component 2232;Driving portion 2231 is driven It is connected to synchronous belt component 2232;Synchronous belt component 2232 is sequentially connected in clamping jaw 221 of uncapping.In the present embodiment, driving portion 2231 be motor, and the driving wheel of synchronous belt component 2232 is connected to motor, and driven wheel is connected to aforementioned interconnecting piece 2221, interconnecting piece 2221 are connected to clamping jaw 221 of uncapping, and then when motor rotates, and can drive the rotation of clamping jaw 221 of uncapping.Further, due to Synchronous belt component 2232 is connected to interconnecting piece 2221 so that interconnecting piece 2221 is the first drive component 222 and the second drive component 223 share, and greatly reduce the volume of entire Quantitative in vitro detecting instrument 10.
Further, third drive component 225 is spindle motor component.Spindle motor component is sequentially connected in clamping jaw of uncapping 221, to drive clamping jaw 221 of uncapping to move up and down.When uncap clamping jaw 221 rotate when and meanwhile coordinate up and down motion, can ensure by The lid of sample tube is opened.Further, by the way that third drive component 225 is arranged so that the up and down motion of clamping jaw 221 of uncapping, energy Enough height for adjusting clamping jaw 221 of uncapping, space availability ratio is high, is suitable for the sample tube of different height, meets in the prior art It tests and analyzes equipment and needs high and low test tube situation used at the same time, greatly increase entire Quantitative in vitro detecting instrument 10 The scope of application efficiently solves the problems, such as that sample is arranged in pairs or groups with test tube in the prior art.
Further, uniform shaking mechanism 230 include clamp assemblies 231, the 4th drive component 232, the 5th drive component 233 with And the 6th drive component 234.4th drive component 232, the 5th drive component 233 and the 6th drive component 234 company of transmission It is connected to clamp assemblies 231.4th drive component 232 is for driving the rotation of clamp assemblies 231 to drive sample tube to rock.5th Drive component 233 is for driving clamp assemblies 231 close or far from the 4th drive component 232.6th drive component 234 is used for Clamp assemblies 231 are driven to move up and down.Sample tube is clamped by clamp assemblies 231, the 4th drive component 232 rotates clamping group Part 231, so that sample tube realization is rolled.The movement of 6th drive component 234 can also be realized in sample tube Under rock, rocked by comprehensive, so ensure the test solution in sample tube is shaken up.
Further, clamp assemblies 231 include wobble-member 2311, the first clamping part 2312 and the second clamping part 2313.It shakes Goods of furniture for display rather than for use 2311 is connected to the first clamping part 2312;Second clamping part 2313 is connected to the 5th drive component 233;First clamping part 2312 and second clamping part 2313 be oppositely arranged.Wobble-member 2311 is located at the first clamping part 2312 far from the second clamping part 2313 One end, when clamping sample tube between the first clamping part 2312 and the second clamping part 2313, wobble-member 2311 plays counterweight Effect, cooperation sample tube are waved.
Further, clamp assemblies 231 are fixedly connected on the 4th drive component 232, when the 4th drive component 232 moves Clamp assemblies 231 are driven to move, so that 2313 close or separate first clamping part 2312 of the second clamping part clamps or releases Sample tube.
Further, in the present embodiment, the 5th drive component 233 be motor, the second clamping part 2313 be sequentially connected in Motor can drive the second clamping part 2313 to rotate when motor rotates.4th drive component 232 include V belt translation component and Motor, by the transmission of V belt translation component, drives 2312 close or separate second clamping of the first clamping part when motor is rotated Portion 2313.
Specifically, the V belt translation component of the 4th drive component 232 is arranged in the top of clamp assemblies 231, passes through connecting plate 2314 are connected to clamp assemblies 231.One end of connecting plate 2314 is fixedly connected on belt, the first clamping part of clamp assemblies 231 2312 and wobble-member 2311 be mounted on connecting plate 2314 the other end, and then when motor drive belt movement when, first clamping Portion 2312 and wobble-member 2311 are moved to the direction close to or far from the second clamping part 2313.
Further, the 6th drive component 234 is linear motor, and clamp assemblies 231 are connected by above-mentioned connecting plate 2314 It is connected to linear motor.When linear motor moves up and down, clamp assemblies 231 can be driven to move up and down, and then can realize pair The upper and lower of sample tube is rocked, and the effect that sample shakes up is further improved.
Further, fixed test tube mechanism 240 includes fixing piece 241 and actuator 242;Fixing piece 241 is for fixing Sample tube;Actuator 242 is for driving fixing piece 241 in 221 lower straight of clamping jaw operation of uncapping, to match closing and opening cover during booting clamping jaw 221 open the lid of sample tube.Specifically, in the present embodiment, fixing piece 241 includes two fixed branch being oppositely arranged Part, sample tube can be fixed on the two and fix between support.It is further alternative, the two fix support select by Flexible material is made, and then can not only fix sample tube well, and will not damage sample tube.
Further, kit conveyer 300 includes multiple kit storage assemblies 310 and kit conveying mechanism 320.Further, kit storage assembly 310 includes multiple accommodating cavity 311 and cartridge clip shell for storing kit 312;Cartridge clip shell 312 there are one being placed in each accommodating cavity 311;Multiple kits 313 overlay cartridge clip shell 312 It is interior.Kit conveying mechanism 320 includes gripper assembly 321, moving track 322 and drive component 323.Gripper assembly 321 is used In by kit 313 from 312 inner clip of cartridge clip shell take out;Gripper assembly 321 is sequentially connected in drive component 323, to drive folder Component 321 is taken to be moved along moving track 322.
In use, rack for test tube is automatically sent to barcode scanning area by 140 barcode scanning of barcode scanning component in sample sampling device 100, It is then passed to and shakes up hood-opening device 200 and shake up, put back to rack for test tube after the completion of shaking up, rack for test tube is sent by sample sampling device 100 It uncaps to hood-opening device 200 is shaken up.Mechanical arm 500 can automatically extract TIP heads, be added to automatically according to absorption dilution is needed It incubates, the mixing area of detection components 400.It is moved to the areas Xi Yang 101 after cleaning TIP.It later again will by sample sampling device 100 Sample send to sample application zone 102 and carries out suction sample by mechanical arm 500.By operating personnel by hand in the reagent of kit conveyer 300 Box storage assembly 310 is put into reagent strip cartridge clip, and kit conveying mechanism 320 can take automatically as needed after detecting cartridge clip Go out the reagent strip of needs and waits for mechanical arm 500 to be loaded in sample application zone 102.The reagent strip being loaded is by kit conveying mechanism 320 send from sample application zone 102 to the incubation area of incubation, detection components 400.Incubative time arrived by kit conveying mechanism 320 from Area is incubated to send to the detection zone detection of incubation, detection components 400.
The foregoing is only a preferred embodiment of the present invention, is not intended to restrict the invention, for the skill of this field For art personnel, the invention may be variously modified and varied.All within the spirits and principles of the present invention, any made by repair Change, equivalent replacement, improvement etc., should all be included in the protection scope of the present invention.It should be noted that:Similar label and letter exist Similar terms are indicated in following attached drawing, therefore, once being defined in a certain Xiang Yi attached drawing, are then not required in subsequent attached drawing It is further defined and is explained.

Claims (10)

1. a kind of Quantitative in vitro detecting instrument, which is characterized in that including:
Sample sampling device, the sample sampling device are used to convey the rack for test tube for placing sample tube;
Hood-opening device is shaken up, the hood-opening device that shakes up is arranged close to the sample sampling device, described to shake up hood-opening device use In the sample tube for carrying out sample sampling device transport uncap and shakes up pass lid;
Kit conveyer, the kit conveyer include multiple kit storage assemblies and kit conveyer Structure;
It incubates, detection components;And
Mechanical arm, the mechanical arm are connected with aspirating needle group, and the aspirating needle group can be transported to the sample by the mechanical arm This sampling device, the kit conveyer and the incubation, detection components.
2. Quantitative in vitro detecting instrument as described in claim 1, which is characterized in that the hood-opening device that shakes up includes:
Support portion;
Cap-opening mechanism, the cap-opening mechanism are connected to the side of the support portion;The cap-opening mechanism includes uncap clamping jaw, first Drive component, the second drive component and third drive component;First drive component, second drive component and institute Third drive component is stated to be sequentially connected in the clamping jaw of uncapping;First drive component is for driving the clamping jaw folder of uncapping Tight or release sample tube lid;Second drive component is for driving the clamping jaw rotation of uncapping;The third driving group Part is for driving the relatively described support portion of clamping jaw of uncapping to move up and down;
Uniform shaking mechanism, the uniform shaking mechanism are connected to the other side of the support portion;The uniform shaking mechanism includes clamp assemblies, Four drive components, the 5th drive component and the 6th drive component;4th drive component, the 5th drive component and 6th drive component is sequentially connected in the clamp assemblies;The clamp assemblies are for being clamped the sample tube;Institute The 4th drive component is stated for driving the clamp assemblies rotation to drive the sample tube to rock;5th drive component For driving the clamp assemblies close or far from the 4th drive component;6th drive component is described for driving Clamp assemblies move up and down;And
Fixed test tube mechanism, the fixed test tube mechanism is arranged below the clamping jaw of uncapping, for fixing the sample tube It is uncapped with clamping jaw of uncapping described in cooperation.
3. Quantitative in vitro detecting instrument as claimed in claim 2, which is characterized in that the clamping jaw of uncapping includes at least three Pawl;The output shaft of first drive component is connected at least three inclined-planes;The connecting pin of at least three holding dogs is respectively provided with There is the skewed slot that connection is matched with the inclined-plane;When first drive component moves, drive at least three holding dogs along institute Inclined-plane sliding is stated, so that at least three holding dogs are close to each other or separate.
4. Quantitative in vitro detecting instrument as claimed in claim 2, which is characterized in that the clamp assemblies include wobble-member, One clamping part and the second clamping part;The wobble-member is connected to first clamping part;Second clamping part be sequentially connected in 5th drive component;First clamping part and second clamping part are oppositely arranged.
5. Quantitative in vitro detecting instrument as claimed in claim 4, which is characterized in that first clamping part is fixedly connected on Four drive components drive first clamping part to move, so that first clamping part when the 4th driving component movement Close to or far from second clamping part.
6. Quantitative in vitro detecting instrument as described in claim 1, which is characterized in that the kit storage assembly includes multiple Accommodating cavity for storing kit and cartridge clip shell;The cartridge clip shell there are one being placed in each described accommodating cavity Body;Multiple kits overlay in the cartridge clip shell.
7. Quantitative in vitro detecting instrument as claimed in claim 6, which is characterized in that the kit conveying mechanism includes gripping Component, moving track and drive component;
The gripper assembly is for taking out the kit from the cartridge clip shell inner clip;The gripper assembly be sequentially connected in The driving component, to drive the gripper assembly to be moved along the moving track.
8. Quantitative in vitro detecting instrument as described in claim 1, which is characterized in that the sample sampling device includes driving Portion, moving guide rail and multiple support plates for holding test tubes frame;The driving portion is sequentially connected in the moving guide rail;Often One support plate is all connected to the moving guide rail.
9. Quantitative in vitro detecting instrument as claimed in claim 8, which is characterized in that the sample sampling device further includes barcode scanning Component, the barcode scanning component shake up hood-opening device setting close to described;The barcode scanning component is used for the sample in the rack for test tube This information carries out barcode scanning.
10. such as claim 1-9 any one of them Quantitative in vitro detecting instruments, which is characterized in that the Quantitative in vitro detection Instrument further includes shell, and the shell has first end and opposite second end;Sample sampling device setting is described the One end, the incubation component and detection components setting in the second end, the mechanical arm setting in the first end and Between the second end.
CN201811094529.9A 2018-09-19 2018-09-19 Quantitative in vitro detecting instrument Pending CN108802413A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CN201811094529.9A CN108802413A (en) 2018-09-19 2018-09-19 Quantitative in vitro detecting instrument
DE212019000092.4U DE212019000092U1 (en) 2018-09-19 2019-06-14 Quantitative in vitro detection device
PCT/CN2019/091430 WO2020057195A1 (en) 2018-09-19 2019-06-14 In vitro quantitative test instrument

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811094529.9A CN108802413A (en) 2018-09-19 2018-09-19 Quantitative in vitro detecting instrument

Publications (1)

Publication Number Publication Date
CN108802413A true CN108802413A (en) 2018-11-13

Family

ID=64082130

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201811094529.9A Pending CN108802413A (en) 2018-09-19 2018-09-19 Quantitative in vitro detecting instrument

Country Status (2)

Country Link
CN (1) CN108802413A (en)
WO (1) WO2020057195A1 (en)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109580923A (en) * 2018-12-24 2019-04-05 徐建顺 A kind of thrombus detection machine
CN109939758A (en) * 2019-03-28 2019-06-28 上海市嘉定区中心医院 A kind of automatic blood pre-treatment of hemorheology detection and liquid relief platform
CN110794158A (en) * 2019-09-27 2020-02-14 广州万孚生物技术股份有限公司 In-vitro diagnosis analyzer, automatic sampling device and automatic sampling method
WO2020057195A1 (en) * 2018-09-19 2020-03-26 基蛋生物科技股份有限公司 In vitro quantitative test instrument
CN112147106A (en) * 2019-06-27 2020-12-29 深圳市帝迈生物技术有限公司 Micro-fluidic sample analysis device and sample introduction mechanism thereof
CN113122436A (en) * 2021-03-29 2021-07-16 中标华谱(山东)智能科技有限公司 Culture dish manufacturing device and method for food microorganism testing
CN113252650A (en) * 2021-04-13 2021-08-13 珠海迪尔生物工程有限公司 Group B workstation
CN114047346A (en) * 2022-01-11 2022-02-15 南京万承生物科技有限公司 Pretreatment module of in-vitro automatic detection system for body fluid sample
CN115639368A (en) * 2022-10-25 2023-01-24 南京帝基生物科技有限公司 Rapid detection kit for respiratory viruses and preparation method thereof
CN117007377A (en) * 2023-08-30 2023-11-07 立子科技(广州)有限公司 Water quality testing divides liquid sampling device
CN115639368B (en) * 2022-10-25 2024-04-26 南京帝基生物科技有限公司 Rapid detection kit for respiratory viruses and preparation method thereof

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080170967A1 (en) * 2007-01-15 2008-07-17 Ids Co., Ltd. Automated test tube cap removal apparatus
CN103760372A (en) * 2013-12-26 2014-04-30 杭州中翰盛泰生物技术有限公司 Full-automatic immediate check meter
CN104403938A (en) * 2014-12-04 2015-03-11 威海世利电子科技有限公司 Intelligent microbial sample processing robot
CN104609348A (en) * 2015-01-26 2015-05-13 长春迪瑞医疗科技股份有限公司 Automatic cover opening device for sample container
CN105628948A (en) * 2016-03-04 2016-06-01 深圳普门科技有限公司 High-speed C reactive protein analyzer and analyzing method thereof
CN106430053A (en) * 2016-09-07 2017-02-22 三峡大学 Medical blood sampling test tube automatic cap taking device and method
CN206580833U (en) * 2017-03-02 2017-10-24 济南百博生物技术股份有限公司 Micro-biological samples processing system device
CN107589273A (en) * 2017-09-30 2018-01-16 迈克医疗电子有限公司 sample analysis detection unit
CN108267355A (en) * 2017-12-29 2018-07-10 迪瑞医疗科技股份有限公司 A kind of automation oscillating uniform device
CN208795750U (en) * 2018-09-19 2019-04-26 基蛋生物科技股份有限公司 Quantitative in vitro detecting instrument

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN204514697U (en) * 2015-04-17 2015-07-29 深圳迈瑞生物医疗电子股份有限公司 Evenly mixing device, robot device and streaming sample preparing instrument
CN105572407B (en) * 2016-01-27 2018-01-16 广州万孚生物技术股份有限公司 Full-automatic fluorescent quantitation immunity analysis instrument and detection method
CN106289908B (en) * 2016-08-17 2020-01-31 广州三瑞医疗器械有限公司 Cell centrifuge and cell centrifugation method
CN108802413A (en) * 2018-09-19 2018-11-13 基蛋生物科技股份有限公司 Quantitative in vitro detecting instrument

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080170967A1 (en) * 2007-01-15 2008-07-17 Ids Co., Ltd. Automated test tube cap removal apparatus
CN103760372A (en) * 2013-12-26 2014-04-30 杭州中翰盛泰生物技术有限公司 Full-automatic immediate check meter
CN104403938A (en) * 2014-12-04 2015-03-11 威海世利电子科技有限公司 Intelligent microbial sample processing robot
CN104609348A (en) * 2015-01-26 2015-05-13 长春迪瑞医疗科技股份有限公司 Automatic cover opening device for sample container
CN105628948A (en) * 2016-03-04 2016-06-01 深圳普门科技有限公司 High-speed C reactive protein analyzer and analyzing method thereof
CN106430053A (en) * 2016-09-07 2017-02-22 三峡大学 Medical blood sampling test tube automatic cap taking device and method
CN206580833U (en) * 2017-03-02 2017-10-24 济南百博生物技术股份有限公司 Micro-biological samples processing system device
CN107589273A (en) * 2017-09-30 2018-01-16 迈克医疗电子有限公司 sample analysis detection unit
CN108267355A (en) * 2017-12-29 2018-07-10 迪瑞医疗科技股份有限公司 A kind of automation oscillating uniform device
CN208795750U (en) * 2018-09-19 2019-04-26 基蛋生物科技股份有限公司 Quantitative in vitro detecting instrument

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020057195A1 (en) * 2018-09-19 2020-03-26 基蛋生物科技股份有限公司 In vitro quantitative test instrument
CN109580923A (en) * 2018-12-24 2019-04-05 徐建顺 A kind of thrombus detection machine
CN109939758A (en) * 2019-03-28 2019-06-28 上海市嘉定区中心医院 A kind of automatic blood pre-treatment of hemorheology detection and liquid relief platform
CN112147106A (en) * 2019-06-27 2020-12-29 深圳市帝迈生物技术有限公司 Micro-fluidic sample analysis device and sample introduction mechanism thereof
CN110794158A (en) * 2019-09-27 2020-02-14 广州万孚生物技术股份有限公司 In-vitro diagnosis analyzer, automatic sampling device and automatic sampling method
CN113122436A (en) * 2021-03-29 2021-07-16 中标华谱(山东)智能科技有限公司 Culture dish manufacturing device and method for food microorganism testing
CN113252650A (en) * 2021-04-13 2021-08-13 珠海迪尔生物工程有限公司 Group B workstation
CN113252650B (en) * 2021-04-13 2024-03-15 珠海迪尔生物工程股份有限公司 Group B workstation
CN114047346A (en) * 2022-01-11 2022-02-15 南京万承生物科技有限公司 Pretreatment module of in-vitro automatic detection system for body fluid sample
CN115639368A (en) * 2022-10-25 2023-01-24 南京帝基生物科技有限公司 Rapid detection kit for respiratory viruses and preparation method thereof
CN115639368B (en) * 2022-10-25 2024-04-26 南京帝基生物科技有限公司 Rapid detection kit for respiratory viruses and preparation method thereof
CN117007377A (en) * 2023-08-30 2023-11-07 立子科技(广州)有限公司 Water quality testing divides liquid sampling device

Also Published As

Publication number Publication date
WO2020057195A1 (en) 2020-03-26

Similar Documents

Publication Publication Date Title
CN108802413A (en) Quantitative in vitro detecting instrument
CN208795750U (en) Quantitative in vitro detecting instrument
CN108918244A (en) It uncaps oscillating uniform device and Quantitative in vitro detecting instrument
RU2559909C2 (en) Automatic device for microbe detection
CN205656203U (en) A sampling device for immune quantitative analysis appearance
JP3068286B2 (en) Analyzer, test element support for analyzer, and method for cleaning test element
CN107290562B (en) A kind of automatic sample handling system for the detection of sample cell high throughput
CN109975277A (en) Chemiluminescence detector and its detection method
JPH06509647A (en) Multilinear automation equipment for immunoassay processing
CN108865659A (en) Nucleic acid extraction and amplification fluorescent detection system
CN208092069U (en) Small size automatic chemical illumination immunity analysis instrument
WO2009085681A2 (en) Automatic loading of sample tubes for clinical analyzer
US11267139B2 (en) Gripper for automated tube handling
CN207866715U (en) Chemiluminescence detector
US20120301357A1 (en) Apparatus and process for opening and closing fluid containers
CN109358201A (en) Full-automatic chemiluminescence immunoassay analysis meter
CN110095621A (en) A kind of full-automatic fluorescence immunity analyzer
CN106980025A (en) The former test tube automatic sampling apparatus in Three Degree Of Freedom multitube position
JP2012112956A (en) Junction, device and process for transporting sample rack
JP2006284575A (en) Closing and opening of container
CN208883861U (en) Nucleic acid extraction and amplification fluorescent detection system
CN213293935U (en) Outpatient service body fluid sample receiving equipment
CN209513823U (en) Luminescence immunoassay instrument
CN208937504U (en) Full-automatic chemiluminescence immunoassay analysis meter
CN114505253B (en) Automatic sorting equipment for sample tubes

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination