CN108785564A - A kind of Chinese yam, dangshen product and preparation method thereof - Google Patents
A kind of Chinese yam, dangshen product and preparation method thereof Download PDFInfo
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- CN108785564A CN108785564A CN201810638903.0A CN201810638903A CN108785564A CN 108785564 A CN108785564 A CN 108785564A CN 201810638903 A CN201810638903 A CN 201810638903A CN 108785564 A CN108785564 A CN 108785564A
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- chinese yam
- dangshen
- chinese
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8994—Coix (Job's tears)
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
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Abstract
The invention discloses a kind of Chinese yam, dangshen products and preparation method thereof, include the material component of following parts by weight：0.5-1.5 parts of anise seed, 5-8 parts of Chinese yam, 2-4 parts of Radix Codonopsis, 2-5 parts of almond, 1-3 parts of peppermint, 1.5-3 parts of hawthorn, 2-4 parts of Chinese Fevervine Herb, 2-6 parts of Semen Coicis, 2-4 parts of leaf lettuce, 0.5-2 parts of garlic essence.Raw material type of the present invention is few, it securely and reliably has no toxic side effect for pure natural raw material, selected medicinal material compatibility is suitable, meet traditional Chinese medicine and pharmacy and modern medical theory, according to the combination principle of monarch, reaches unexpected therapeutic effect, using convenient source, convenient for materials, cheap, preparation method is simple.Chinese yam, dangshen product prepared by the application, after being taken according to the course for the treatment of, has apparent therapeutic effect for dyspeptic symptom.
Description
Technical field
The invention belongs to field of health care food more particularly to a kind of Chinese yam, dangshen product and preparation method thereof.
Background technology
Functional dyspepsia FD (FD) is also known as indigestion, refer to epigastric pain, big belly, early satiety, belch, appetite not
It shakes, the malaise symptoms such as Nausea and vomiting, excludes one group of clinical syndrome for causing the organic disease of above-mentioned symptom on inspection.Disease
Shape is sustainable or recurrent exerbation, the course of disease are more than one month or add up more than 12 weeks in past December.Functional digestive
Bad cardinal symptom is as follows：
(1) early satieties refer to having full sense soon after feeding, so that dietary intake significantly reduces.
(2) big bellies mostly occur in after the meal, or are in duration dining postemphasis.
(3) early saturation big belly is often accompanied by belch to.Nausea and vomiting is not common, is frequently experienced in gastric emptying obvious postpone
Patient, vomiting be mostly meal gastric content.
(4) many patients of are simultaneously with the mental symptoms such as insomnia, anxiety, depression, headache, absent minded.These diseases
Shape is related with " probably cancer " psychology in some patientss.
(5) symptoms in the course of disease can also change, and how slow onset is, for years, duration or recurrent exerbation, no
Few patient has diet, the risk factors such as spirit.
The medicament categories for the treatment of indigestion illness are numerous at present, such as west spring mouth reservoir, Itopride Hydrochloride capsule, fourth
The Western medicine such as quinoline, metoclopramide have certain side effect although Western medicine is quick, good effect, cannot cure indigestion illness.
Based on this, how to realize that fundamentally curing indigestion is a technical problem that technical personnel in the field need to solve at present.
Number of patent application provides for 201410169679.7 patent of invention and a kind for the treatment of dyspeptic drug and system
The raw material group of Preparation Method, the invention effective ingredient becomes：It is Amomum cardamomum, bush, pepper, Radix picrorrhizae, sea cucumber, black flour leaf, red
Lichen, Exocarpium Citri Grandis, Glochidion puberum, sea-buckthorn, Prunella vulgaris, blood clam, China fir, Chinese ixeris herb, buckeye and rhizoma nelumbinis；With invigorating spleen and reinforcing stomach, pleasant
The effect of analgesic, promoting blood circulation and removing blood stasis, nourishing qi and blood, to abdominal discomfort caused by treatment indigestion or pain, glutted, heartburn, anti-
Acid, heating are reluctant that the symptoms such as feed or few feed, sleeping and eating difficulty peace have notable curative effect, but the patent is using names such as sea cucumbers
Your Chinese medicine, cost is higher, it is difficult to popularize.
Number of patent application provides a kind of Tea containing traditional Chinese medicine improving stomach function for 20171144946.5 patent of invention, including
The raw material of following parts by weight proportioning：42-46 parts of honeysuckle, 40-44 parts of radix polygonati officinalis, 32-38 parts of the fruit of Chinese wolfberry, 28-33 parts of sealwort,
It is 22-26 parts of campanulaceae, 20-25 parts of Poria cocos, 19-23 parts of pueraria lobata, 10-18 parts of cape jasmine, 10-15 parts of coix seed, 8-10 parts of peppermint, auxiliary
Expect that 5-10 parts and appropriate amount of water, the auxiliary material are made of the raw material of following parts by weight：10-15 parts of Icing Sugar, 13-17 parts of dextrin.It should
Improve the Tea containing traditional Chinese medicine of stomach function, it is raw material to select natural rare edible Chinese herbal medicine, and fragrant odour is sweet tasty and refreshing, improves stomach function,
Promote digestion and go stomach fire, eliminate because in indigestion, stomach putrefaction increase, stomach fire surplus, abnormal heat, mouth disease or undesirable life
Halitosis and canker sore and excessive internal heat caused by custom etc., but the effect of patent treatment functional dyspepsia FD is general.
Invention content
In order to overcome the above problems of the prior art, a kind of Chinese yam, dangshen product is provided, using pure natural raw material,
Securely and reliably, it has no toxic side effect, selected medicinal material compatibility is suitable, meets traditional Chinese medicine and pharmacy and modern medical theory, is helped according to the monarch and his subjects
The combination principle made reaches unexpected therapeutic effect for indigestion symptom, using convenient source, convenient for materials, valence
Lattice are cheap, while preparation method is simple.
A kind of Chinese yam, dangshen product, includes the material component of following parts by weight：0.5-1.5 parts of anise seed, 5-8 parts of Chinese yam,
2-4 parts of Radix Codonopsis, 2-5 parts of almond, 1-3 parts of peppermint, 1.5-3 parts of hawthorn, 2-4 parts of Chinese Fevervine Herb, 2-6 parts of Semen Coicis, 2-4 parts of leaf lettuce,
0.5-2 parts of garlic essence.
Preferably, include the material component of following parts by weight：0.5 part of anise seed, 5 parts of Chinese yam, 2 parts of Radix Codonopsis, almond 2
Part, 1 part of peppermint, 1.5 parts of hawthorn, 2 parts of Chinese Fevervine Herb, 2 parts of Semen Coicis, 2 parts of leaf lettuce, 0.5 part of garlic essence.
In any of the above-described scheme preferably, include the material component of following parts by weight：1 part of anise seed, 6 parts of Chinese yam, party
3 parts of ginseng, 4 parts of almond, 2 parts of peppermint, 2 parts of hawthorn, 3 parts of Chinese Fevervine Herb, 4 parts of Semen Coicis, 3 parts of leaf lettuce, 1 part of garlic essence.
In any of the above-described scheme preferably, include the material component of following parts by weight：1.5 parts of anise seed, 8 parts of Chinese yam,
4 parts of Radix Codonopsis, 5 parts of almond, 3 parts of peppermint, 3 parts of hawthorn, 4 parts of Chinese Fevervine Herb, 6 parts of Semen Coicis, 4 parts of leaf lettuce, 2 parts of garlic essence.
In any of the above-described scheme preferably, the dosage form of the Chinese yam, dangshen product be powder, pulvis, tablet, granule,
Any one in decoction, oral solution, honey ointment body, honeydew, beverage or tea bag preparation.
In any of the above-described scheme preferably, the dosage form of the Chinese medicine composition is powder, pulvis, tablet, granule, soup
Any one in agent, oral solution, honey ointment body, honeydew, beverage or tea bag preparation.
The present invention also provides the preparation method of above-mentioned Chinese yam, dangshen product, Chinese yam, dangshen product is tablet, preparation method packet
Include following steps：
(1) will be pressed after anise seed, Chinese yam, Radix Codonopsis, almond, peppermint, hawthorn, Chinese Fevervine Herb, Semen Coicis, leaf lettuce feedstock processing
Proportioning weighs after crushing workshop and crushing；
(2) mixes load weighted raw material and garlic essence in step (1) in mixing machine, and setting incorporation time turns
Speed releases raw material after mixing；
(3) raw material mixed is carried out tabletting by using tablet press machine；
(4) it is packed after tablettings, after the completion of packaging, the qualified storage of product laboratory detection.
Preferably, it is needed to anise seed, Chinese yam, Radix Codonopsis, almond, peppermint, hawthorn, chicken droppings before step (1) sieving
Rattan, Semen Coicis, leaf lettuce are tested, and are crushing workshop ultramicro grinding according to the ratio after the assay was approved.
In any of the above-described scheme preferably, it is ultramicro grinding that the step (1), which crushes, Ultramicro-powder grain size after ultramicro grinding
It is 10~60 μm.
In any of the above-described scheme preferably, ultramicro grinding, the air-flow pressure of airslide disintegrating mill are carried out using airslide disintegrating mill
Power is 600~8000kPa, and charging rate is 180~200rmin-1, grade frequency be 20~30Hz, grinding time be 20~
30min obtains Ultramicro-powder.
In any of the above-described scheme preferably, the incorporation time in step (2) is 20-30 minutes, 20 revs/min.
In any of the above-described scheme preferably, 3.8 thousand Ns of tablet press machine pressure in the step (3), loading 5mm, every
Net content is between 1.05-1.10 grams.
In any of the above-described scheme preferably, the specific practice of step (4) packaging is：Per bottled 60 Chinese medicine groups
Object tablet is closed, is sealed later, seal and bottle is transmitted to outer packing workshop has been labelled, vanning.
Using anise seed, Chinese yam, Radix Codonopsis, almond, peppermint, hawthorn, Chinese Fevervine Herb, Semen Coicis, leaf lettuce, big in the application formula
Garlic essence is as raw material.
Garlic essence promotes gastrointestinal disturbances to absorb, whole intestines stomach invigorating, and main ingredient is unsaturated fatty acid, often edible big
Garlic can lead to the five internal organs, strengthening the spleen and stomach, go cold-dampness, solve pestilence.There is preferable side work(to pre- cardiovascular, artery sclerosis, can also strengthen cycle
System, helping reduces cholesterol and fat, has anti-inflammatory, infection strengthen immunity, reaches heat preservation and purifies the blood and enteron aisle sundries, for a long time
Constitution can be improved by taking.The garlic essence of the application is the finished product bought in the market.
Leaf lettuce carries pure and fresh taste containing lettuce foline, slightly bitter, after eating can stimulating intestine and stomach, increase saliva, gastric juice,
The effect of secretion of digestive ferment and bile has appetizing and hearty appetite, promotees digestion.Iron content in leaf lettuce is very high, and
In leaf lettuce under the action of many organic acids and phytoenzyme, the irony in leaf lettuce is easier to be digested, and eats lettuce
Lettuce leaf has mends iron effect well, can promote the synthesis of hemoglobin, have therapeutic efficiency to various anemias, is suitble to pregnant woman, old
People, the crowd of long-term bed are edible.The content of iodine is also very high in leaf lettuce, and iodine mainly acts on Thyreoidine and swashs
Element can adjust the basic metabolism of human body, promote psychology and body development, can alleviate the anxiety of mood, clinically can be used to lettuce
Lettuce leaf auxiliary treatment Thyroid Gland Swell, atherosclerosis etc..Leaf lettuce is compared with lettuce, and protein will be higher by 40%, fat
More 1 times, dietary fiber is high by 33%, and carrotene is high by 83%, and vitamin B1 is 2 times more, and vitamin C is even more to be higher by 68%.
Semen Coicis, Semen Coicis pellet ooze sweet benefit, can inducing diuresis for removing edema, and can strengthening spleen and middle warmer.It is usually used in treating caused by the insufficiency of the spleen with overabundance of dampness
The symptoms such as abdominal distension, difficult urination, oedema, beriberi edema；Semen Coicis can be oozed except spleen is wet, and invigorating the spleen to arrest diarrhea is particularly good at treatment spleen
Diarrhea caused by empty wetness hyperactivity；Semen Coicis can excreting dampness eliminating impediment, can relaxing muscles and tendons arteries and veins, mitigate contraction, can be used for treating the insufficiency of the spleen with overabundance of dampness and muscle
The illnesss such as arteries and veins contraction urgency pain；Semen Coicis can be used for treating lung carbuncle pectoralgia, cough a lot of phlegm also can be used with the heat of gut purge, removing pus and relieving carbuncle
In diseases such as treatment acute appendicitis.
Chinese Fevervine Herb is sweet in flavor, sour；It is mild-natured.The thoughts of returning home；Liver；Spleen；Kidney channel.Dispelling wind and eliminating dampness；Promoting digestion and removing indigestion；Removing toxicity for detumescence；Promoting blood circulation stops
Bitterly.Cure mainly arthralgia pain due to rheumatism；Dyspeptic abdominal distention；Infantile malnutrition；Diarrhea；Dysentery；Heatstroke；Jaundice；Hepatitis；Hepatosplenomegaly；Cough；Scrofula
Scrofula；Acute appendicitis；Nameless sores or boils；Foot is wet swollen rotten；Burn and scald；Eczema；Dermatitis；Traumatic injury；Snake flood dragon scorpion stings.
Peppermint, peppermint acrid flavour are cool in nature；Return lung, Liver Channel；Faint scent, which rises, to be dissipated；With wind-dispelling heat-dissipating, refresh oneself, throat, thoroughly
Rash, effect of Xie Yu；Cure mainly wind-heat table disease, dizziness of having a headache, red eye, swell pain, sore throat sound dumb, nasosinusitis, toothache, measles without adequate eruption, urticaria
Itch, liver-depressed hypochondrium pain gastral cavity is swollen, scrofula tuberculosis.
Almond, expelling phlegm and arresting coughing are relievingd asthma, ease constipation, and lower gas opens numbness, have moistening lung, cough-relieving, laxation and other effects, to dry cough without phlegm,
The diseases such as chronic cough of deficiency lung have certain mitigation；It is aobvious for the symptoms curative effect such as more phlegm, cough, asthma caused by cold
It writes.
Hawthorn can promote the decomposition of fat and protein containing lipase and crataegolic acid；Hawthorn dry wine is to shigella dysenteriae, change
Shape bacillus, Escherichia coli have antibacterial action, are the good merchantable brands for treating enterogastric diseases.But hawthorn acid food, this herbal cuisine stomach
Ulcers should not be eaten more；Hawthorn has promoting blood circulation to lead to stasis of blood effect, and pregnant woman should not eat more.
Chinese yam, it is sweet in flavor, it mends and oiliness, fragrant without dry, treatment insufficiency of the spleen diarrhoea effect is good.Chinese yam is to mitigate strengthening by means of tonics medicine,
The wide intestines of invigorating spleen and reinforcing stomach have a better effect the chronic diarrhea of gastrointestinal function decline.The enriching yin of Chinese yam energy and energy dampness removing, can lubricate and can receive
It is puckery.Diarrhea can be treated, is because it has the function of diuresis, small facility so that moisture is discharged from bladder, reduce in enteron aisle
Moisture, so reducing the half congealed symptom rushed down.The wide intestines of Chinese yam spleen-strengtheningporridge benefit stomach and can antidiarrheal because Chinese yam can flat enriching spleen-QI, reinforce
The work(of tonifying Qi fortune spleen, therefore can only defecate.
The effect of anise seed：It can make fragrance, be usually used in the cooking of the wheaten food such as meat, seafood and sesame seed cake.It is used as medicine in traditional Chinese medicine,
Warm-natured, acrid flavour returns liver,kidney,spleen, stomach.Function temperature liver kidney, warm stomach gas dissipate plug knot, eliminating cold to stop pain, regulating qi-flowing for harmonizing stomach.For cold hernia
Abdominal pain, the testis swelling and hanging down of either of the testes, dysmenorrhes, few abdomen crymodynia, abdominal distention, the diseases such as deficiency of food vomiting and diarrhoea.
The primary efficacy of Radix Codonopsis, Radix Codonopsis is tonifying Qi.Most preferably it is used for lassitude hypodynamia, lassitude usually.Voice is droning, conscious
Shortness of breath, slightly Lung Qi deficiency weak person of the activity with regard to syndrome characterized by dyspnea.The people of deficiency of spleen-QI and stomach-QI, weakness of limbs are laid particular emphasis on, loss of appetite is defecated dilute
It is half congealed.Meanwhile the simultaneous energy blood-nourishing of Radix Codonopsis tonifying Qi.
Advantageous effect
A kind of Chinese yam, dangshen product of present invention offer and preparation method thereof, includes the material component of following parts by weight：Fennel
0.5-1.5 parts of seed, 5-8 parts of Chinese yam, 2-4 parts of Radix Codonopsis, 2-5 parts of almond, 1-3 parts of peppermint, 1.5-3 parts of hawthorn, 2-4 parts of Chinese Fevervine Herb,
2-6 parts of Semen Coicis, 2-4 parts of leaf lettuce, 0.5-2 parts of garlic essence.Raw material type of the present invention is few, is pure natural raw material, securely and reliably, nothing
Toxic side effect, selected medicinal material compatibility is suitable, meets traditional Chinese medicine and pharmacy and modern medical theory, former according to the compatibility of monarch
Then, reach unexpected therapeutic effect, using convenient source, convenient for materials, cheap, preparation method is simple.The application
The Chinese yam, dangshen product of preparation after being taken according to the course for the treatment of, has apparent therapeutic effect for dyspeptic symptom.
Specific implementation mode
In order to be best understood from technical scheme of the present invention and advantage, below by way of specific implementation mode, to the present invention do into
One step explanation.
Embodiment 1.1
A kind of Chinese yam, dangshen product, includes the material component of following parts by weight：0.5 part of anise seed, 5 parts of Chinese yam, Radix Codonopsis 2
Part, 2 parts of almond, 1 part of peppermint, 1.5 parts of hawthorn, 2 parts of Chinese Fevervine Herb, 2 parts of Semen Coicis, 2 parts of leaf lettuce, 0.5 part of garlic essence.
Above-mentioned Chinese yam, dangshen product is tablet, and preparation method includes the following steps：
Step (1) locates anise seed, Chinese yam, Radix Codonopsis, almond, peppermint, hawthorn, Chinese Fevervine Herb, Semen Coicis, lettuce leaf raw material in advance
After reason, crushing is dried at normal temperatures, the said goods examine qualified raw material anise seed, Chinese yam, Radix Codonopsis, almond, peppermint, mountain
Short, bristly hair or beard, Chinese Fevervine Herb, Semen Coicis, leaf lettuce are matched by technology preparation is crushing workshop using airslide disintegrating mill progress ultramicro grinding, air-flow
The stream pressure of pulverizer is 600~8000kPa, and charging rate is 180~200rmin-1, grade frequency is 20~30Hz,
Grinding time is 20~30min, obtains Ultramicro-powder, and Ultramicro-powder grain size is 10~60 μm after ultramicro grinding, and all materials exist after crushing
Electronic scale is weighed between weighing；Pretreatment of raw material includes by anise seed, Chinese yam, Radix Codonopsis, almond, peppermint, hawthorn, chicken droppings
Rattan, Semen Coicis, leaf lettuce are impregnated in brine respectively, brine strength 5-10%, and cleaning is pulled out and dried under rear room temperature.
Step (2) is transmitted to groove profile compound department, workshop temperature the load weighted raw material in workshop is weighed by sterile transferring window
14 degree, humidity 30% are spent, raw material and the dispensing of garlic essence in CH-200 mixing machines, incorporation time is 20-30 minutes, 20 turns/
Point, incorporation time is set by technological requirement, material is released with stainless steel barrel；When mixing, it is passed through nitrogen, protects active ingredient.
Step (3), will mix raw material by sterile transferring window be transmitted to tabletting workshop carry out tabletting, tablet press machine model
ZPW-19B, 3.8 thousand Ns of tablet press machine pressure, loading 5mm, every 1 gram of net content check a net content in every 10 minutes,
Net content is asked to reach between 1.05-1.10 grams；
Step (4), every bottled 60 Chinese medicine composition tablets, seal, have sealed bottle being transmitted to outsourcing entrucking later
Between labelled, case；The bottle labelling that inner packing workshop is transmitted, label print the date of manufacture, post label and are packed into greatly
Case, per 120 bottles of box installed；
Step (5), the qualified storage of product laboratory detection.
Embodiment 2
A kind of Chinese yam, dangshen product, includes the material component of following parts by weight：1 part of anise seed, 6 parts of Chinese yam, 3 parts of Radix Codonopsis,
4 parts of almond, 2 parts of peppermint, 2 parts of hawthorn, 3 parts of Chinese Fevervine Herb, 4 parts of Semen Coicis, 3 parts of leaf lettuce, 1 part of garlic essence.
Above-mentioned Chinese yam, dangshen product is tablet, and preparation method includes the following steps：
Step (1) locates anise seed, Chinese yam, Radix Codonopsis, almond, peppermint, hawthorn, Chinese Fevervine Herb, Semen Coicis, lettuce leaf raw material in advance
After reason, crushing is dried at normal temperatures, the said goods examine qualified raw material anise seed, Chinese yam, Radix Codonopsis, almond, peppermint, mountain
Short, bristly hair or beard, Chinese Fevervine Herb, Semen Coicis, leaf lettuce are matched by technology preparation is crushing workshop using airslide disintegrating mill progress ultramicro grinding, air-flow
The stream pressure of pulverizer is 600~8000kPa, and charging rate is 180~200rmin-1, grade frequency is 20~30Hz,
Grinding time is 20~30min, obtains Ultramicro-powder, and Ultramicro-powder grain size is 10~60 μm after ultramicro grinding, and all materials exist after crushing
Electronic scale is weighed between weighing；Pretreatment of raw material includes by anise seed, Chinese yam, Radix Codonopsis, almond, peppermint, hawthorn, chicken droppings
Rattan, Semen Coicis, leaf lettuce are impregnated in brine respectively, brine strength 5-10%, and cleaning is pulled out and dried under rear room temperature.
Step (2) is transmitted to groove profile compound department, workshop temperature the load weighted raw material in workshop is weighed by sterile transferring window
14 degree, humidity 30% are spent, raw material and the dispensing of garlic essence in CH-200 mixing machines, incorporation time is 20-30 minutes, 20 turns/
Point, incorporation time is set by technological requirement, material is released with stainless steel barrel；When mixing, it is passed through nitrogen, protects active ingredient.
Step (3), will mix raw material by sterile transferring window be transmitted to tabletting workshop carry out tabletting, tablet press machine model
ZPW-19B, 3.8 thousand Ns of tablet press machine pressure, loading 5mm, every 1 gram of net content check a net content in every 10 minutes,
Net content is asked to reach between 1.05-1.10 grams；
Step (4), every bottled 60 Chinese medicine composition tablets, seal, have sealed bottle being transmitted to outsourcing entrucking later
Between labelled, case；The bottle labelling that inner packing workshop is transmitted, label print the date of manufacture, post label and are packed into greatly
Case, per 120 bottles of box installed；
Step (5), the qualified storage of product laboratory detection.
Embodiment 3
A kind of Chinese yam, dangshen product, includes the material component of following parts by weight：1.5 parts of anise seed, 8 parts of Chinese yam, Radix Codonopsis 4
Part, 5 parts of almond, 3 parts of peppermint, 3 parts of hawthorn, 4 parts of Chinese Fevervine Herb, 6 parts of Semen Coicis, 4 parts of leaf lettuce, 2 parts of garlic essence.
Above-mentioned Chinese yam, dangshen product is tablet, and preparation method includes the following steps：
Step (1) locates anise seed, Chinese yam, Radix Codonopsis, almond, peppermint, hawthorn, Chinese Fevervine Herb, Semen Coicis, lettuce leaf raw material in advance
After reason, crushing is dried at normal temperatures, the said goods examine qualified raw material anise seed, Chinese yam, Radix Codonopsis, almond, peppermint, mountain
Short, bristly hair or beard, Chinese Fevervine Herb, Semen Coicis, leaf lettuce are matched by technology preparation is crushing workshop using airslide disintegrating mill progress ultramicro grinding, air-flow
The stream pressure of pulverizer is 600~8000kPa, and charging rate is 180~200rmin-1, grade frequency is 20~30Hz,
Grinding time is 20~30min, obtains Ultramicro-powder, and Ultramicro-powder grain size is 10~60 μm after ultramicro grinding, and all materials exist after crushing
Electronic scale is weighed between weighing；Pretreatment of raw material includes by anise seed, Chinese yam, Radix Codonopsis, almond, peppermint, hawthorn, chicken droppings
Rattan, Semen Coicis, leaf lettuce are impregnated in brine respectively, brine strength 5-10%, and cleaning is pulled out and dried under rear room temperature.
Step (2) is transmitted to groove profile compound department, workshop temperature the load weighted raw material in workshop is weighed by sterile transferring window
14 degree, humidity 30% are spent, raw material and the dispensing of garlic essence in CH-200 mixing machines, incorporation time is 20-30 minutes, 20 turns/
Point, incorporation time is set by technological requirement, material is released with stainless steel barrel；When mixing, it is passed through nitrogen, protects active ingredient.
Step (3), will mix raw material by sterile transferring window be transmitted to tabletting workshop carry out tabletting, tablet press machine model
ZPW-19B, 3.8 thousand Ns of tablet press machine pressure, loading 5mm, every 1 gram of net content check a net content in every 10 minutes,
Net content is asked to reach between 1.05-1.10 grams；
Step (4), every bottled 60 Chinese medicine composition tablets, seal, have sealed bottle being transmitted to outsourcing entrucking later
Between labelled, case；The bottle labelling that inner packing workshop is transmitted, label print the date of manufacture, post label and are packed into greatly
Case, per 120 bottles of box installed；
Step (5), the qualified storage of product laboratory detection.
Comparative example 1
A kind of Chinese yam, dangshen product, includes the material component of following parts by weight：1 part of anise seed, 6 parts of Chinese yam, 3 parts of Radix Codonopsis,
2 parts of peppermint, 2 parts of hawthorn, 3 parts of Chinese Fevervine Herb, 4 parts of Semen Coicis, 3 parts of leaf lettuce, 1 part of garlic essence.
Above-mentioned Chinese yam, dangshen product is tablet, and preparation method includes the following steps：
Step (1), by after anise seed, Chinese yam, Radix Codonopsis, peppermint, hawthorn, Chinese Fevervine Herb, Semen Coicis, leaf lettuce pretreatment of raw material,
Be dried crushing at normal temperatures, the said goods examine qualified raw material anise seed, Chinese yam, Radix Codonopsis, peppermint, hawthorn, Chinese Fevervine Herb,
Semen Coicis, leaf lettuce are matched by technology preparation is crushing workshop using airslide disintegrating mill progress ultramicro grinding, the gas of airslide disintegrating mill
Flowing pressure is 600~8000kPa, and charging rate is 180~200rmin-1, grade frequency is 20~30Hz, and grinding time is
20~30min obtains Ultramicro-powder, and Ultramicro-powder grain size is 10~60 μm after ultramicro grinding, all materials electricity consumption between weighing after crushing
Sub- scale is weighed；Pretreatment of raw material includes by anise seed, Chinese yam, Radix Codonopsis, peppermint, hawthorn, Chinese Fevervine Herb, Semen Coicis, leaf lettuce point
It is not impregnated in brine, brine strength 5-10%, cleans, pull out and dried under rear room temperature.
Step (2) is transmitted to groove profile compound department, workshop temperature the load weighted raw material in workshop is weighed by sterile transferring window
14 degree, humidity 30% are spent, raw material and the dispensing of garlic essence in CH-200 mixing machines, incorporation time is 20-30 minutes, 20 turns/
Point, incorporation time is set by technological requirement, material is released with stainless steel barrel；When mixing, it is passed through nitrogen, protects active ingredient.
Step (3), will mix raw material by sterile transferring window be transmitted to tabletting workshop carry out tabletting, tablet press machine model
ZPW-19B, 3.8 thousand Ns of tablet press machine pressure, loading 5mm, every 1 gram of net content check a net content in every 10 minutes,
Net content is asked to reach between 1.05-1.10 grams；
Step (4), every bottled 60 Chinese medicine composition tablets, seal, have sealed bottle being transmitted to outsourcing entrucking later
Between labelled, case；The bottle labelling that inner packing workshop is transmitted, label print the date of manufacture, post label and are packed into greatly
Case, per 120 bottles of box installed；
Step (6), the qualified storage of product laboratory detection.
Comparative example 2
A kind of Chinese yam, dangshen product, includes the material component of following parts by weight：1 part of anise seed, 6 parts of Chinese yam, 3 parts of Radix Codonopsis,
4 parts of almond, 2 parts of peppermint, 2 parts of hawthorn, 3 parts of Chinese Fevervine Herb, 4 parts of Semen Coicis, 3 parts of leaf lettuce.
Above-mentioned Chinese yam, dangshen product is tablet, and preparation method includes the following steps：
Step (1) locates anise seed, Chinese yam, Radix Codonopsis, almond, peppermint, hawthorn, Chinese Fevervine Herb, Semen Coicis, lettuce leaf raw material in advance
After reason, crushing is dried at normal temperatures, the said goods examine qualified raw material anise seed, Chinese yam, Radix Codonopsis, almond, peppermint, mountain
Short, bristly hair or beard, Chinese Fevervine Herb, Semen Coicis, leaf lettuce are matched by technology preparation is crushing workshop using airslide disintegrating mill progress ultramicro grinding, air-flow
The stream pressure of pulverizer is 600~8000kPa, and charging rate is 180~200rmin-1, grade frequency is 20~30Hz,
Grinding time is 20~30min, obtains Ultramicro-powder, and Ultramicro-powder grain size is 10~60 μm after ultramicro grinding, and all materials exist after crushing
Electronic scale is weighed between weighing；Pretreatment of raw material includes by anise seed, Chinese yam, Radix Codonopsis, almond, peppermint, hawthorn, chicken droppings
Rattan, Semen Coicis, leaf lettuce are impregnated in brine respectively, brine strength 5-10%, and cleaning is pulled out and dried under rear room temperature.
Step (2) is transmitted to groove profile compound department, workshop temperature the load weighted raw material in workshop is weighed by sterile transferring window
14 degree, humidity 30% are spent, raw material is launched in CH-200 mixing machines, incorporation time is 20-30 minutes, 20 revs/min, by work
Skill requires setting incorporation time, and material is released with stainless steel barrel；When mixing, it is passed through nitrogen, protects active ingredient.
Step (3), will mix raw material by sterile transferring window be transmitted to tabletting workshop carry out tabletting, tablet press machine model
ZPW-19B, 3.8 thousand Ns of tablet press machine pressure, loading 5mm, every 1 gram of net content check a net content in every 10 minutes,
Net content is asked to reach between 1.05-1.10 grams；
Step (4), every bottled 60 Chinese medicine composition tablets, seal, have sealed bottle being transmitted to outsourcing entrucking later
Between labelled, case；The bottle labelling that inner packing workshop is transmitted, label print the date of manufacture, post label and are packed into greatly
Case, per 120 bottles of box installed；
Step (5), the qualified storage of product laboratory detection.
Comparative example 3
Unlike a kind of Chinese yam, dangshen product and embodiment 2, include the material component of following parts by weight：Anise seed 1
Part, 6 parts of Chinese yam, 5 parts of Radix Codonopsis, 4 parts of almond, 2 parts of peppermint, 2 parts of hawthorn, 3 parts of Chinese Fevervine Herb, 4 parts of Semen Coicis, 3 parts of leaf lettuce, garlic
1 part of essence.
Comparative example 4
Unlike a kind of Chinese yam, dangshen product and embodiment 2, include the material component of following parts by weight：Anise seed 1
Part, 6 parts of Chinese yam, 3 parts of Radix Codonopsis, 4 parts of almond, 2 parts of peppermint, 2 parts of hawthorn, 1 part of Chinese Fevervine Herb, 4 parts of Semen Coicis, 3 parts of leaf lettuce, garlic
1 part of essence.
(1) animal acute toxicity test is carried out to tablet prepared by the present invention：
Drug：Raw material used in the present invention is commercially available from common Chinese shop, and specification meets national Chinese medicine standard.
Subjects：Small white mouse, weight is in 50g or so, male and female random selection.
Method and result：Small white mouse 10 is taken, it is 24 hours or so hungry, it feeds the application at twice daily by every and implements
Chinese medicine composition prepared by example 2,10 tablets once, continuous to feed after a week, observes 10 days, and mouse activity is normal, non-toxic reaction, nothing
Death shows the tablet of the present invention without acute toxicity, clinical medicine dose safety.
(2) long-term toxicity test for animals is carried out to tablet prepared by the present invention：
Experimental animal：Big white mouse, weight is in 120-130g, male and female random selection.
Method and result：Big white mouse 20 is taken, is divided into 2 groups, every group 10, wherein the 1st group is used as administration group, often by every
It feeds for it 2 times, 10 tablets once, and the 2nd group of diet as a control group, continuous 90 days, surveys weight, 24 after last time is administered
Hour sacrificed by decapitation surveys blood, routine urinalysis, liver function, renal function, the internal organ such as coring, kidney, the variation of tissues observed form, observation
The effect of dosage, observation diet, movable variation, experiments have shown that administration group is compared with the control group without significant changes, it is non-toxic
Reaction, is a kind of safe drugs.
Chinese medicine composition prepared by the application has carried out clinical test, and clinical criteria is as follows：
It cures：Sign and symptom improve completely, and diet is normal, and appetite is good；
It is effective：Sign and symptom significantly improve, and diet is normal, and appetite is preferable；
Effectively：Sign and symptom have change, and random thoughts are slightly uncomfortable, but can receive；
In vain：Symptom, sign are compared with pre-treatment without any change after treatment；
1) clinical diagnosis：Do not feel like eating, gasteremphraxis have the symptoms such as feeling of pain, indigestion.
2) in order to verify clinical efficacy, the application has carried out clinic trial, under the premise of the principle of voluntariness, randomly selects it
In 320 patients, and be randomly divided into seven groups, every group of 40 people.
3) therapy：Every group is taken Chinese yam, dangshen product sheet prepared by the present embodiment 1-3 and comparative example 1-4 respectively
Agent three times a day ten every time, is taken, 5 days as a treatment course, six courses for the treatment of totally after the meal.
Specific treatment results are referring to table 1.
It takes one week after terminating six courses for the treatment of and (carries out normal diet in one week, but excessively greasy food cannot be eaten
Object) it is counted, situation see the table below shown in 1, illustrates that the application Chinese yam, dangshen product has and significantly treats dyspeptic work
With.
1 curative effect situation of table
By above-mentioned data in table 1 it is found that after the Chinese medicine composition for taking the present invention, effective percentage maintains 90%-
97.5%, wherein cure rate maintains 85%-95%.Comparative example 1-4 is since ingredient or content are adjusted, and effective percentage is only
27.5%-37.5% is maintained, wherein cure rate is only up to 7.5%.
Data above further illustrates that the present invention has apparent therapeutic effect for dyspeptic symptom, according to treatment
After journey is taken, indigestion symptom can be cured, will not be recurred in a short time.In addition the raw material type of the application is few, is pure natural
Drug securely and reliably has no toxic side effect, and selected medicinal material compatibility is suitable, meets traditional Chinese medicine and pharmacy and modern medical theory, according to monarch
Minister helps the combination principle made, reaches unexpected therapeutic effect, using convenient source, convenient for materials, cheap, preparation side
Method is simple.
It should be noted that the above embodiments are only used to illustrate the technical solution of the present invention., rather than its limitations；Although
Present invention has been described in detail with reference to the aforementioned embodiments, it will be understood by those of ordinary skill in the art that：It is still
Either which part or all technical features can be carried out so that technical scheme described in the above embodiments is modified
Equivalent replacement；And these modifications or replacements, it does not separate the essence of the corresponding technical solution various embodiments of the present invention technical side
The range of case.
Claims (8)
1. a kind of Chinese yam, dangshen product, is characterized in that：Include the material component of following parts by weight：0.5-1.5 parts of anise seed, Chinese yam
5-8 parts, 2-4 parts of Radix Codonopsis, 2-5 parts of almond, 1-3 parts of peppermint, 1.5-3 parts of hawthorn, 2-4 parts of Chinese Fevervine Herb, 2-6 parts of Semen Coicis, leaf lettuce
2-4 parts, 0.5-2 parts of garlic essence.
2. a kind of Chinese yam, dangshen product as described in claim 1, it is characterised in that：Include the material component of following parts by weight：
0.5 part of anise seed, 5 parts of Chinese yam, 2 parts of Radix Codonopsis, 2 parts of almond, 1 part of peppermint, 1.5 parts of hawthorn, 2 parts of Chinese Fevervine Herb, 2 parts of Semen Coicis, lettuce
2 parts of leaf, 0.5 part of garlic essence.
3. a kind of Chinese yam, dangshen product as described in claim 1, it is characterised in that：Include the material component of following parts by weight：
1 part of anise seed, 6 parts of Chinese yam, 3 parts of Radix Codonopsis, 4 parts of almond, 2 parts of peppermint, 2 parts of hawthorn, 3 parts of Chinese Fevervine Herb, 4 parts of Semen Coicis, leaf lettuce 3
Part, 1 part of garlic essence.
4. a kind of Chinese yam, dangshen product as described in claim 1, it is characterised in that：Include the material component of following parts by weight：
1.5 parts of anise seed, 8 parts of Chinese yam, 4 parts of Radix Codonopsis, 5 parts of almond, 3 parts of peppermint, 3 parts of hawthorn, 4 parts of Chinese Fevervine Herb, 6 parts of Semen Coicis, leaf lettuce 4
Part, 2 parts of garlic essence.
5. a kind of Chinese yam, dangshen product as described in claim 1, it is characterised in that：The dosage form of the Chinese yam, dangshen product is scattered
Any one in agent, pulvis, tablet, granule, decoction, oral solution, honey ointment body, honeydew, beverage or tea bag preparation.
6. the preparation method of the Chinese yam, dangshen product as described in any one of claim 1-5, Chinese yam, dangshen product is tablet,
It is characterized in that：Preparation method includes the following steps：
(1) by after anise seed, Chinese yam, Radix Codonopsis, almond, peppermint, hawthorn, Chinese Fevervine Herb, Semen Coicis, leaf lettuce feedstock processing according to the ratio
After crushing workshop and crushing, weigh；
(2) mixes load weighted raw material and garlic essence in step (1) in mixing machine, setting incorporation time, rotating speed,
Raw material is released after mixing；
(3) raw material mixed is carried out tabletting by using tablet press machine；
(4) it is packed after tablettings, after the completion of packaging, the qualified storage of product laboratory detection.
7. a kind of preparation method of Chinese yam, dangshen product as claimed in claim 6, it is characterised in that：Step (1) sieving
Before need to test to anise seed, Chinese yam, Radix Codonopsis, almond, peppermint, hawthorn, Chinese Fevervine Herb, Semen Coicis, leaf lettuce, after the assay was approved
Crushing workshop ultramicro grinding according to the ratio.
8. a kind of preparation method of Chinese yam, dangshen product as claimed in claim 6, it is characterised in that：The step (1) crushes
For ultramicro grinding, Ultramicro-powder grain size is 10~60 μm after ultramicro grinding.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101062229A (en) * | 2007-05-19 | 2007-10-31 | 周海萍 | Nutritional medicine for promoting digestion |
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|---|---|---|---|---|
| CN101062229A (en) * | 2007-05-19 | 2007-10-31 | 周海萍 | Nutritional medicine for promoting digestion |
| CN103495080A (en) * | 2013-10-16 | 2014-01-08 | 刘运波 | Traditional Chinese medicine for treating infantile anorexia |
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