CN108721522A - It is a kind of to treat dyspeptic Chinese medicine composition and preparation method thereof - Google Patents
It is a kind of to treat dyspeptic Chinese medicine composition and preparation method thereof Download PDFInfo
- Publication number
- CN108721522A CN108721522A CN201810638905.XA CN201810638905A CN108721522A CN 108721522 A CN108721522 A CN 108721522A CN 201810638905 A CN201810638905 A CN 201810638905A CN 108721522 A CN108721522 A CN 108721522A
- Authority
- CN
- China
- Prior art keywords
- parts
- leaf
- chinese medicine
- medicine composition
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8984—Dendrobium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Dyspeptic Chinese medicine composition and preparation method thereof is treated the invention discloses a kind of, includes the material component of following parts by weight：1-3 parts of the membrane of a chicken's gizzard, 2-4 parts of dried orange peel, 5-8 parts of leaf of Herba Apii graveolentis, 1-3 parts of Radix Paeoniae Alba, 0.5-2 parts of the stem of noble dendrobium, 1.5-3 parts of hawthorn, 2-4 parts of Chinese Fevervine Herb, 3-6 parts of polished rice, 1-2 parts of leaf lettuce, 2-5 parts of egg oil.Raw material type of the present invention is few, it securely and reliably has no toxic side effect for natural medicine, selected medicinal material compatibility is suitable, meet traditional Chinese medicine and pharmacy and modern medical theory, according to the combination principle of monarch, reaches unexpected therapeutic effect, using convenient source, convenient for materials, cheap, preparation method is simple.There is apparent therapeutic effect for dyspeptic symptom, after being taken according to the course for the treatment of, indigestion symptom can be cured, will not be recurred in a short time.
Description
Technical field
The invention belongs to the field of Chinese medicines more particularly to a kind for the treatment of dyspeptic Chinese medicine composition and preparation method thereof.
Background technology
Functional dyspepsia FD (FD) is also known as indigestion, refer to epigastric pain, big belly, early satiety, belch, appetite not
It shakes, the malaise symptoms such as Nausea and vomiting, excludes one group of clinical syndrome for causing the organic disease of above-mentioned symptom on inspection.Disease
Shape is sustainable or recurrent exerbation, the course of disease are more than one month or add up more than 12 weeks in past December.Functional digestive
Bad cardinal symptom is as follows：
(1) early satieties refer to having full sense soon after feeding, so that dietary intake significantly reduces.
(2) big bellies mostly occur in after the meal, or are in duration dining postemphasis.
(3) early saturation big belly is often accompanied by belch to.Nausea and vomiting is not common, is frequently experienced in gastric emptying obvious postpone
Patient, vomiting be mostly meal gastric content.
(4) many patients of are simultaneously with the mental symptoms such as insomnia, anxiety, depression, headache, absent minded.These diseases
Shape is related with " probably cancer " psychology in some patientss.
(5) symptoms in the course of disease can also change, and how slow onset is, for years, duration or recurrent exerbation, no
Few patient has diet, the risk factors such as spirit.
The medicament categories for the treatment of indigestion illness are numerous at present, such as west spring mouth reservoir, Itopride Hydrochloride capsule, fourth
The Western medicine such as quinoline, metoclopramide have certain side effect although Western medicine is quick, good effect, cannot cure indigestion illness.
Based on this, how to realize that fundamentally curing indigestion is a technical problem that technical personnel in the field need to solve at present.
Number of patent application provides for 201410169679.7 patent of invention and a kind for the treatment of dyspeptic drug and system
The raw material group of Preparation Method, the invention effective ingredient becomes：It is Amomum cardamomum, bush, pepper, Radix picrorrhizae, sea cucumber, black flour leaf, red
Lichen, Exocarpium Citri Grandis, Glochidion puberum, sea-buckthorn, Prunella vulgaris, blood clam, China fir, Chinese ixeris herb, buckeye and rhizoma nelumbinis；With invigorating spleen and reinforcing stomach, pleasant
The effect of analgesic, promoting blood circulation and removing blood stasis, nourishing qi and blood, to abdominal discomfort caused by treatment indigestion or pain, glutted, heartburn, anti-
Acid, heating are reluctant that the symptoms such as feed or few feed, sleeping and eating difficulty peace have notable curative effect, but the patent is using names such as sea cucumbers
Your Chinese medicine, cost is higher, it is difficult to popularize.
Number of patent application provides a kind of Tea containing traditional Chinese medicine improving stomach function for 20171144946.5 patent of invention, including
The raw material of following parts by weight proportioning：42-46 parts of honeysuckle, 40-44 parts of radix polygonati officinalis, 32-38 parts of the fruit of Chinese wolfberry, 28-33 parts of sealwort,
It is 22-26 parts of campanulaceae, 20-25 parts of Poria cocos, 19-23 parts of pueraria lobata, 10-18 parts of cape jasmine, 10-15 parts of coix seed, 8-10 parts of peppermint, auxiliary
Expect that 5-10 parts and appropriate amount of water, the auxiliary material are made of the raw material of following parts by weight：10-15 parts of Icing Sugar, 13-17 parts of dextrin.It should
Improve the Tea containing traditional Chinese medicine of stomach function, it is raw material to select natural rare edible Chinese herbal medicine, and fragrant odour is sweet tasty and refreshing, improves stomach function,
Promote digestion and go stomach fire, eliminate because in indigestion, stomach putrefaction increase, stomach fire surplus, abnormal heat, mouth disease or undesirable life
Halitosis and canker sore and excessive internal heat caused by custom etc., but the effect of patent treatment functional dyspepsia FD is general, Bu Nenggen
It removes.
Invention content
In order to overcome the above problems of the prior art, provide it is a kind for the treatment of dyspeptic Chinese medicine composition, be
Natural medicine securely and reliably has no toxic side effect, and selected medicinal material compatibility is suitable, meets traditional Chinese medicine and pharmacy and modern medical theory,
According to the combination principle of monarch, reach unexpected therapeutic effect, it is cheap convenient for materials using convenient source,
Preparation method is simple.
It is a kind of to treat dyspeptic Chinese medicine composition, include the material component of following parts by weight：It is 1-3 parts of the membrane of a chicken's gizzard, old
2-4 parts of skin, 5-8 parts of leaf of Herba Apii graveolentis, 1-3 parts of Radix Paeoniae Alba, 0.5-2 parts of the stem of noble dendrobium, 1.5-3 parts of hawthorn, 2-4 parts of Chinese Fevervine Herb, 3-6 parts of polished rice,
1-2 parts of leaf lettuce, 2-5 parts of egg oil.
Preferably, include the material component of following parts by weight：1 part of the membrane of a chicken's gizzard, 2 parts of dried orange peel, 5 parts of leaf of Herba Apii graveolentis, Radix Paeoniae Alba 1
Part, 0.5 part of the stem of noble dendrobium, 1.5 parts of hawthorn, 2 parts of Chinese Fevervine Herb, 3 parts of polished rice, 1 part of leaf lettuce, 2 parts of egg oil.
In any of the above-described scheme preferably, include the material component of following parts by weight：2 parts of the membrane of a chicken's gizzard, 3 parts of dried orange peel, celery
6 parts of dish leaf, 2 parts of Radix Paeoniae Alba, 1 part of the stem of noble dendrobium, 2 parts of hawthorn, 3 parts of Chinese Fevervine Herb, 4.5 parts of polished rice, 1.5 parts of leaf lettuce, 3.5 parts of egg oil.
In any of the above-described scheme preferably, include the material component of following parts by weight：2.5 parts of the membrane of a chicken's gizzard, dried orange peel 3.5
Part, 7 parts of leaf of Herba Apii graveolentis, 2.5 parts of Radix Paeoniae Alba, 1.5 parts of the stem of noble dendrobium, 2.5 parts of hawthorn, 3.5 parts of Chinese Fevervine Herb, 5 parts of polished rice, 2 parts of leaf lettuce, yolk
4 parts of oil.
In any of the above-described scheme preferably, include the material component of following parts by weight：3 parts of the membrane of a chicken's gizzard, 4 parts of dried orange peel, celery
8 parts of dish leaf, 3 parts of Radix Paeoniae Alba, 2 parts of the stem of noble dendrobium, 3 parts of hawthorn, 4 parts of Chinese Fevervine Herb, 6 parts of polished rice, 2 parts of leaf lettuce, 5 parts of egg oil.
In any of the above-described scheme preferably, the dosage form of the dyspeptic Chinese medicine composition of the treatment be powder, pulvis,
Any one in tablet, granule, decoction, oral solution, honey ointment body, honeydew, beverage or tea bag preparation.
In any of the above-described scheme preferably, the dosage form of the Chinese medicine composition is powder, pulvis, tablet, granule, soup
Any one in agent, oral solution, honey ointment body, honeydew, beverage or tea bag preparation.
The present invention also provides the preparation methods of the dyspeptic Chinese medicine composition of above-mentioned treatment, treat dyspeptic Chinese medicine
Composition is tablet, and preparation method includes the following steps：
(1) will be after the membrane of a chicken's gizzard, dried orange peel, leaf of Herba Apii graveolentis, Radix Paeoniae Alba, the stem of noble dendrobium, hawthorn, Chinese Fevervine Herb, polished rice, leaf lettuce feedstock processing
According to the ratio after crushing workshop and crushing, weigh；
(2) mixes load weighted raw material and egg oil in step (1) in mixing machine, and setting incorporation time turns
Speed releases raw material after mixing；
(3) raw material mixed is carried out tabletting by using tablet press machine；
(4) it is packed after tablettings, after the completion of packaging, the qualified storage of product laboratory detection.
Preferably, it is needed to the membrane of a chicken's gizzard, dried orange peel, leaf of Herba Apii graveolentis, Radix Paeoniae Alba, the stem of noble dendrobium, hawthorn, chicken before step (1) sieving
Dung rattan, polished rice, leaf lettuce are tested, and are crushing workshop ultramicro grinding according to the ratio after the assay was approved.
In any of the above-described scheme preferably, it is ultramicro grinding that the step (1), which crushes, Ultramicro-powder grain size after ultramicro grinding
It is 10~60 μm.
In any of the above-described scheme preferably, ultramicro grinding, the air-flow pressure of airslide disintegrating mill are carried out using airslide disintegrating mill
Power is 600~8000kPa, and charging rate is 180~200rmin-1, grade frequency be 20~30Hz, grinding time be 20~
30min obtains Ultramicro-powder.
In any of the above-described scheme preferably, the preparation method of step (2) the mesolecithal oil is：After the cooked son of egg
Yolk is left, yolk grinding is let off in pot later as powder plus water infusion, until there is egg oil.Egg oil boils egg
Yolk is left after ripe son, grinding lets off infusion in pot after becoming powder, until there is egg oil.Egg oil can be protected effectively
Strengthening the spleen and stomach to promote stomach to secrete hydrochloric acid in gastric juice, the case where can not only treating indigestion, while can also treat vomiting.Separately
Outside, if body difference long-time indigestion cause it is weakness of the spleen and the stomach, take after also can be good at health of body.
In any of the above-described scheme preferably, the volume ratio of the yolk powder and water is 1:2-4.
In any of the above-described scheme preferably, the volume ratio of the yolk powder and water is 1:3.
In any of the above-described scheme preferably, the volume ratio of the yolk powder and water is 1:2.
In any of the above-described scheme preferably, the volume ratio of the yolk powder and water is 1:4.
In any of the above-described scheme preferably, the incorporation time in step (2) is 20-30 minutes, 20 revs/min.
In any of the above-described scheme preferably, 3.8 thousand Ns of tablet press machine pressure in the step (3), loading 5mm, every
Net content is between 1.05-1.10 grams.
In any of the above-described scheme preferably, the specific practice of step (4) packaging is：Per bottled 60 Chinese medicine groups
Object tablet is closed, is sealed later, seal and bottle is transmitted to outer packing workshop has been labelled, vanning.
The application formula in using the membrane of a chicken's gizzard, dried orange peel, leaf of Herba Apii graveolentis, Radix Paeoniae Alba, the stem of noble dendrobium, hawthorn, Chinese Fevervine Herb, polished rice, leaf lettuce,
Egg oil is as raw material.
Egg oil also known as chicken oil, can be applied with also oral administration, and egg oil has heat-clearing moisturizing, anti-inflammatory analgetic, convergence myogenic
With the effect in protection sore face.Now with egg oil treat disease it is a lot of, such as outer painting can treat eczema, scald, pernio, ulcer on the shank,
Impetigo, aphtha, thrush, favus of the scalp, diaper dermatitis, hemorrhoid, exfoliative inflammation of lips etc., it is for oral administration to treat gastric ulcer, chronic gastritis, digestion not
Good, pertussis etc..
In leaf lettuce and leaf lettuce leaf all contain lettuce foline, carry pure and fresh taste, slightly bitter, eat after can stimulating intestine and stomach,
The effect of secretion for increasing saliva, gastric juice, digestive ferment and bile has appetizing and hearty appetite, promotees digestion.Ferro element in leaf lettuce contains
Amount is very high, and many organic acids and under the action of phytoenzyme in leaf lettuce, and the irony in leaf lettuce is more easily disappeared by human body
Change and absorb, edible leaf lettuce has mends iron effect well, can promote the synthesis of hemoglobin, have treatment work(to various anemias
Effect is suitble to the crowd of pregnant woman, old man, long-term bed edible.The content of iodine is also very high in leaf lettuce, and iodine is mainly made
For thyroid hormone, the basic metabolism of human body can be adjusted, promotes psychology and body development, the anxiety of mood can be alleviated, faced
Leaf lettuce auxiliary treatment Thyroid Gland Swell, atherosclerosis etc. are can be used on bed.For leaf lettuce compared with lettuce, protein wants high
Go out 40%, fat is 1 times more, and dietary fiber is high by 33%, and carrotene is high by 83%, and vitamin B1 is 2 times more, and vitamin C is even more to be higher by
68%.
Polished rice, it is sweet in flavor, it is mild-natured.Energy Energy benefit taste, relieving thirst and restlessness.Taste impairment of yin for vomitting, caused by rush down dysentery or warm heat disease, stomach
Unsaturated vapor etc..It relaxes bowel, the crude fibre molecule of rice bran layer helps gastrointestinal peristalsis, to curative effects such as stomach trouble, constipation, hemorrhoid
Very well.Immunity is improved, polished rice can improve immune function of human body, promote blood circulation,.
Nourishing the stomach neutralizes hydrochloric acid in gastric juice, alleviates stomachache.Promoting blood circulation promotes human qi and blood running, is suitable for treatment syndrome of blood stasis.
Chinese Fevervine Herb is sweet in flavor, sour；It is mild-natured.The thoughts of returning home；Liver；Spleen；Kidney channel.Dispelling wind and eliminating dampness；Promoting digestion and removing indigestion；Removing toxicity for detumescence；Promoting blood circulation stops
Bitterly.Cure mainly arthralgia pain due to rheumatism；Dyspeptic abdominal distention；Infantile malnutrition；Diarrhea；Dysentery；Heatstroke；Jaundice；Hepatitis；Hepatosplenomegaly；Cough；Scrofula
Scrofula；Acute appendicitis；Nameless sores or boils；Foot is wet swollen rotten；Burn and scald；Eczema；Dermatitis；Traumatic injury；Snake flood dragon scorpion stings.
The stem of noble dendrobium has the function of nourishing yin and nourishing blood.Containing relatively rich glucide, have the function of enhancing immune function.
Modern pharmacological research also shows：Dendrobium candidum can improve stress ability, have good antifatigue, resisting oxygen lack.Iron sheet stone
Dry measure used in former times is reinforcing stomach reg fluid medicine.It is the common drug treated epigastric pain, upper abdomen and gone up painful.Modern medical experiment confirms：The stem of noble dendrobium is to the spleen-stomach diseases
In common pathogenic bacteria helicobacter pylori have good inhibiting effect, help to treat atrophic gastritis, superficial gastritis, 12
The illness of the Helicobacter pyloris such as Duodenalulcer；Meanwhile, it is capable to promote the secretion of gastric juice, enhance the emptying ability of stomach, helps
Digestion.
Cloudy receipts sweat is held back in Radix Paeoniae Alba, nourishing blood and liver, analgesic in delaying.Control chest and abdomen pain over the hypochondriac region, diarrhea dysentery abdominal pain, spontaneous sweating, the deficiency of Yin
Fever, irregular menstruation, uterine bleeding, with inferior.
Hawthorn can promote the decomposition of fat and protein containing lipase and crataegolic acid；Hawthorn dry wine is to shigella dysenteriae, change
Shape bacillus, Escherichia coli have antibacterial action, are the good merchantable brands for treating enterogastric diseases.But hawthorn acid food, this herbal cuisine stomach
Ulcers should not be eaten more；Hawthorn has promoting blood circulation to lead to stasis of blood effect, and pregnant woman should not eat more.
Dried orange peel, spread of pungent taste helps to keep warm, fragrant odour are longer than qi-regulating, can enter spleen and lung, therefore can go scattered sluggishness of lung-QI and promoting the circulation of qi
In width, the diseases such as stagnant, chest diaphragm feeling of fullness and the taste stagnation of the circulation of vital energy, abdominal fullness and distention are gathered around for lung qi.Can be additionally used in damp retention in middle-jiao, gastral cavity abdomen swollen ruffian,
The diseases such as loose stool diarrhea and many coughs of phlegm；For diseases such as the reduction of spleen deficiency diet, indigestion and nausea and vomiting.
The effect of the membrane of a chicken's gizzard：Food digesting stomach fortifying, arresting seminal emission.It removes food retention, strengthening the spleen and stomach.Dyspepsia turgor is controlled, vomiting gastric disorder causing nausea is rushed down
Dysentery, infantile malnutrition due to digestive disturbances or intestinalparasites are quenched one's thirst, and are lost and are drowned, larynx numbness acute tonsillitis, noma aphtha.It is sweet in flavor mild-natured, enter taste bladder warp, there is stomach strengthening and digestion promoting, changes product row
Stone, admittedly the effects that taking the photograph contracting urine.Modern pharmacological research thinks that the membrane of a chicken's gizzard mainly contains gastric hormone, keratin, the ingredients such as amino acid.
The effects that having and increase gastric secretion and gastro-intestinal digestion ability, accelerating the rate of evacuation of stomach.
Leaf of Herba Apii graveolentis, the soothing the liver antihypertensive effect of celery, a kind of alkaline components isolated from celery seed have calmness to animal
Effect, can play tranquilizing the mind to human body, be conducive to stable mood, eliminate irritated.Celery contains diuresis active ingredient, eliminates body
Interior sodium retention, inducing diuresis to remove edema.Celery, which is high fiber food, has effects that anti-cancer and cancer-preventing, its enteral digested effect generates a kind of
The substance of lignin or enteral fat, this substance are a kind of antioxidants, and when high concentration can inhibit the carcinogenic of intestinal bacterium generation
Substance.It may also speed up the duration of runs of excrement in the intestine, reduces contact of the carcinogenic substance with mucous membrane of colon, reaches prevention colon
The purpose of cancer.Celery iron-holder is higher, can supplement the loss of women's menses, is the good vegetable of Patients with iron deficiency anemia, and food can be kept away
Exempt from ochrodermia, drying, lusterless complexion, and lustrous eyes can be made, hair is shiny black.The leaf of celery, stem contain volatile materials,
Ju not be fragrant, the appetite of people can be enhanced.Celery Juice also has hypoglycemic effect.Often eat a little celeries, can neutralize uric acid and in vivo
Acidic materials, to prevent gout have better effects.
Advantageous effect
Present invention offer is a kind of to treat dyspeptic Chinese medicine composition and preparation method thereof, includes the original of following parts by weight
Expect component：1-3 parts of the membrane of a chicken's gizzard, 2-4 parts of dried orange peel, 5-8 parts of leaf of Herba Apii graveolentis, 1-3 parts of Radix Paeoniae Alba, 0.5-2 parts of the stem of noble dendrobium, 1.5-3 parts of hawthorn,
2-4 parts of Chinese Fevervine Herb, 3-6 parts of polished rice, 1-2 parts of leaf lettuce, 2-5 parts of egg oil.Raw material type of the present invention is few, is natural medicine,
Securely and reliably, it has no toxic side effect, selected medicinal material compatibility is suitable, meets traditional Chinese medicine and pharmacy and modern medical theory, is helped according to the monarch and his subjects
The combination principle made reaches unexpected therapeutic effect, cheap convenient for materials using convenient source, preparation method letter
It is single.There is apparent therapeutic effect for dyspeptic symptom, after being taken according to the course for the treatment of, indigestion symptom can be cured,
It will not recur in a short time.
Specific implementation mode
In order to be best understood from technical scheme of the present invention and advantage, below by way of specific implementation mode, to the present invention do into
One step explanation.
Embodiment 1.1
It is a kind of to treat dyspeptic Chinese medicine composition, include the material component of following parts by weight：1 part of the membrane of a chicken's gizzard, dried orange peel
2 parts, 5 parts of leaf of Herba Apii graveolentis, 1 part of Radix Paeoniae Alba, 0.5 part of the stem of noble dendrobium, 1.5 parts of hawthorn, 2 parts of Chinese Fevervine Herb, 3 parts of polished rice, 1 part of leaf lettuce, egg oil 2
Part.
The above-mentioned dyspeptic Chinese medicine composition for the treatment of is tablet, and preparation method includes the following steps：
It is step (1), the membrane of a chicken's gizzard, dried orange peel, leaf of Herba Apii graveolentis, Radix Paeoniae Alba, the stem of noble dendrobium, hawthorn, Chinese Fevervine Herb, polished rice, lettuce leaf raw material is pre-
After processing, crushing is dried at normal temperatures, the said goods examine the qualified raw material the membrane of a chicken's gizzard, dried orange peel, leaf of Herba Apii graveolentis, Radix Paeoniae Alba, stone
Dry measure used in former times, hawthorn, Chinese Fevervine Herb, polished rice, leaf lettuce are matched by technology preparation carries out ultramicro grinding in crushing workshop using airslide disintegrating mill,
The stream pressure of airslide disintegrating mill is 600~8000kPa, and charging rate is 180~200rmin-1, grade frequency be 20~
30Hz, grinding time are 20~30min, obtain Ultramicro-powder, and Ultramicro-powder grain size is 10~60 μm after ultramicro grinding, property after crushing
Material electronic scale between weighing is weighed；Pretreatment of raw material include by the membrane of a chicken's gizzard, dried orange peel, leaf of Herba Apii graveolentis, Radix Paeoniae Alba, the stem of noble dendrobium, hawthorn,
Chinese Fevervine Herb, polished rice, leaf lettuce are impregnated in brine respectively, brine strength 5-10%, and cleaning is pulled out and dried in the air under rear room temperature
It is dry.
Step (2) prepares egg oil：Yolk will be left after the cooked son of egg, yolk grinding lets off pot after becoming powder
In plus water infusion, until there is egg oil, the volume ratio of yolk powder and water is 1:2-4
Step (3) is transmitted to groove profile compound department, workshop temperature the load weighted raw material in workshop is weighed by sterile transferring window
14 degree, humidity 30% are spent, raw material and egg oil dispensing in CH-200 mixing machines, incorporation time is 20-30 minutes, 20 turns/
Point, incorporation time is set by technological requirement, material is released with stainless steel barrel；When mixing, it is passed through nitrogen, protects active ingredient.
Step (4), will mix raw material by sterile transferring window be transmitted to tabletting workshop carry out tabletting, tablet press machine model
ZPW-19B, 3.8 thousand Ns of tablet press machine pressure, loading 5mm, every 1 gram of net content check a net content in every 10 minutes,
Net content is asked to reach between 1.05-1.10 grams；
Step (5), every bottled 60 Chinese medicine composition tablets, seal, have sealed bottle being transmitted to outsourcing entrucking later
Between labelled, case；The bottle labelling that inner packing workshop is transmitted, label print the date of manufacture, post label and are packed into greatly
Case, per 120 bottles of box installed；
Step (6), the qualified storage of product laboratory detection.
Embodiment 2
It is a kind of to treat dyspeptic Chinese medicine composition, include the material component of following parts by weight：2 parts of the membrane of a chicken's gizzard, dried orange peel
3 parts, 6 parts of leaf of Herba Apii graveolentis, 2 parts of Radix Paeoniae Alba, 1 part of the stem of noble dendrobium, 2 parts of hawthorn, 3 parts of Chinese Fevervine Herb, 4.5 parts of polished rice, 1.5 parts of leaf lettuce, egg oil
3.5 part.
The above-mentioned dyspeptic Chinese medicine composition for the treatment of is tablet, and preparation method includes the following steps：
It is step (1), the membrane of a chicken's gizzard, dried orange peel, leaf of Herba Apii graveolentis, Radix Paeoniae Alba, the stem of noble dendrobium, hawthorn, Chinese Fevervine Herb, polished rice, lettuce leaf raw material is pre-
After processing, crushing is dried at normal temperatures, the said goods examine the qualified raw material the membrane of a chicken's gizzard, dried orange peel, leaf of Herba Apii graveolentis, Radix Paeoniae Alba, stone
Dry measure used in former times, hawthorn, Chinese Fevervine Herb, polished rice, leaf lettuce are matched by technology preparation carries out ultramicro grinding in crushing workshop using airslide disintegrating mill,
The stream pressure of airslide disintegrating mill is 600~8000kPa, and charging rate is 180~200rmin-1, grade frequency be 20~
30Hz, grinding time are 20~30min, obtain Ultramicro-powder, and Ultramicro-powder grain size is 10~60 μm after ultramicro grinding, property after crushing
Material electronic scale between weighing is weighed；Pretreatment of raw material include by the membrane of a chicken's gizzard, dried orange peel, leaf of Herba Apii graveolentis, Radix Paeoniae Alba, the stem of noble dendrobium, hawthorn,
Chinese Fevervine Herb, polished rice, leaf lettuce are impregnated in brine respectively, brine strength 5-10%, and cleaning is pulled out and dried in the air under rear room temperature
It is dry.
Step (2) prepares egg oil：Yolk will be left after the cooked son of egg, yolk grinding lets off pot after becoming powder
In plus water infusion, until there is egg oil, the volume ratio of yolk powder and water is 1:2-4
Step (3) is transmitted to groove profile compound department, workshop temperature the load weighted raw material in workshop is weighed by sterile transferring window
14 degree, humidity 30% are spent, raw material and egg oil dispensing in CH-200 mixing machines, incorporation time is 20-30 minutes, 20 turns/
Point, incorporation time is set by technological requirement, material is released with stainless steel barrel；When mixing, it is passed through nitrogen, protects active ingredient.
Step (4), will mix raw material by sterile transferring window be transmitted to tabletting workshop carry out tabletting, tablet press machine model
ZPW-19B, 3.8 thousand Ns of tablet press machine pressure, loading 5mm, every 1 gram of net content check a net content in every 10 minutes,
Net content is asked to reach between 1.05-1.10 grams；
Step (5), every bottled 60 Chinese medicine composition tablets, seal, have sealed bottle being transmitted to outsourcing entrucking later
Between labelled, case；The bottle labelling that inner packing workshop is transmitted, label print the date of manufacture, post label and are packed into greatly
Case, per 120 bottles of box installed；
Step (6), the qualified storage of product laboratory detection.
Embodiment 3
It is a kind of to treat dyspeptic Chinese medicine composition, include the material component of following parts by weight：It is 2.5 parts of the membrane of a chicken's gizzard, old
3.5 parts of skin, 7 parts of leaf of Herba Apii graveolentis, 2.5 parts of Radix Paeoniae Alba, 1.5 parts of the stem of noble dendrobium, 2.5 parts of hawthorn, 3.5 parts of Chinese Fevervine Herb, 5 parts of polished rice, leaf lettuce 2
Part, 4 parts of egg oil.
The above-mentioned dyspeptic Chinese medicine composition for the treatment of is tablet, and preparation method includes the following steps：
It is step (1), the membrane of a chicken's gizzard, dried orange peel, leaf of Herba Apii graveolentis, Radix Paeoniae Alba, the stem of noble dendrobium, hawthorn, Chinese Fevervine Herb, polished rice, lettuce leaf raw material is pre-
After processing, crushing is dried at normal temperatures, the said goods examine the qualified raw material the membrane of a chicken's gizzard, dried orange peel, leaf of Herba Apii graveolentis, Radix Paeoniae Alba, stone
Dry measure used in former times, hawthorn, Chinese Fevervine Herb, polished rice, leaf lettuce are matched by technology preparation carries out ultramicro grinding in crushing workshop using airslide disintegrating mill,
The stream pressure of airslide disintegrating mill is 600~8000kPa, and charging rate is 180~200rmin-1, grade frequency be 20~
30Hz, grinding time are 20~30min, obtain Ultramicro-powder, and Ultramicro-powder grain size is 10~60 μm after ultramicro grinding, property after crushing
Material electronic scale between weighing is weighed；Pretreatment of raw material include by the membrane of a chicken's gizzard, dried orange peel, leaf of Herba Apii graveolentis, Radix Paeoniae Alba, the stem of noble dendrobium, hawthorn,
Chinese Fevervine Herb, polished rice, leaf lettuce are impregnated in brine respectively, brine strength 5-10%, and cleaning is pulled out and dried in the air under rear room temperature
It is dry.
Step (2) prepares egg oil：Yolk will be left after the cooked son of egg, yolk grinding lets off pot after becoming powder
In plus water infusion, until there is egg oil, the volume ratio of yolk powder and water is 1:3.
Step (3) is transmitted to groove profile compound department, workshop temperature the load weighted raw material in workshop is weighed by sterile transferring window
14 degree, humidity 30% are spent, raw material and egg oil dispensing in CH-200 mixing machines, incorporation time is 20-30 minutes, 20 turns/
Point, incorporation time is set by technological requirement, material is released with stainless steel barrel；When mixing, it is passed through nitrogen, protects active ingredient.
Step (4), will mix raw material by sterile transferring window be transmitted to tabletting workshop carry out tabletting, tablet press machine model
ZPW-19B, 3.8 thousand Ns of tablet press machine pressure, loading 5mm, every 1 gram of net content check a net content in every 10 minutes,
Net content is asked to reach between 1.05-1.10 grams；
Step (5), every bottled 60 Chinese medicine composition tablets, seal, have sealed bottle being transmitted to outsourcing entrucking later
Between labelled, case；The bottle labelling that inner packing workshop is transmitted, label print the date of manufacture, post label and are packed into greatly
Case, per 120 bottles of box installed；
Step (6), the qualified storage of product laboratory detection.
Embodiment 4
It is a kind of to treat dyspeptic Chinese medicine composition, include the material component of following parts by weight：3 parts of the membrane of a chicken's gizzard, dried orange peel
4 parts, 8 parts of leaf of Herba Apii graveolentis, 3 parts of Radix Paeoniae Alba, 2 parts of the stem of noble dendrobium, 3 parts of hawthorn, 4 parts of Chinese Fevervine Herb, 6 parts of polished rice, 2 parts of leaf lettuce, 5 parts of egg oil.
The above-mentioned dyspeptic Chinese medicine composition for the treatment of is tablet, and preparation method includes the following steps：
It is step (1), the membrane of a chicken's gizzard, dried orange peel, leaf of Herba Apii graveolentis, Radix Paeoniae Alba, the stem of noble dendrobium, hawthorn, Chinese Fevervine Herb, polished rice, lettuce leaf raw material is pre-
After processing, crushing is dried at normal temperatures, the said goods examine the qualified raw material the membrane of a chicken's gizzard, dried orange peel, leaf of Herba Apii graveolentis, Radix Paeoniae Alba, stone
Dry measure used in former times, hawthorn, Chinese Fevervine Herb, polished rice, leaf lettuce are matched by technology preparation carries out ultramicro grinding in crushing workshop using airslide disintegrating mill,
The stream pressure of airslide disintegrating mill is 600~8000kPa, and charging rate is 180~200rmin-1, grade frequency be 20~
30Hz, grinding time are 20~30min, obtain Ultramicro-powder, and Ultramicro-powder grain size is 10~60 μm after ultramicro grinding, property after crushing
Material electronic scale between weighing is weighed；Pretreatment of raw material include by the membrane of a chicken's gizzard, dried orange peel, leaf of Herba Apii graveolentis, Radix Paeoniae Alba, the stem of noble dendrobium, hawthorn,
Chinese Fevervine Herb, polished rice, leaf lettuce are impregnated in brine respectively, brine strength 5-10%, and cleaning is pulled out and dried in the air under rear room temperature
It is dry.
Step (2) prepares egg oil：Yolk will be left after the cooked son of egg, yolk grinding lets off pot after becoming powder
In plus water infusion, until there is egg oil, the volume ratio of yolk powder and water is 1:4.
Step (3) is transmitted to groove profile compound department, workshop temperature the load weighted raw material in workshop is weighed by sterile transferring window
14 degree, humidity 30% are spent, raw material and egg oil dispensing in CH-200 mixing machines, incorporation time is 20-30 minutes, 20 turns/
Point, incorporation time is set by technological requirement, material is released with stainless steel barrel；When mixing, it is passed through nitrogen, protects active ingredient.
Step (4), will mix raw material by sterile transferring window be transmitted to tabletting workshop carry out tabletting, tablet press machine model
ZPW-19B, 3.8 thousand Ns of tablet press machine pressure, loading 5mm, every 1 gram of net content check a net content in every 10 minutes,
Net content is asked to reach between 1.05-1.10 grams；
Step (5), every bottled 60 Chinese medicine composition tablets, seal, have sealed bottle being transmitted to outsourcing entrucking later
Between labelled, case；The bottle labelling that inner packing workshop is transmitted, label print the date of manufacture, post label and are packed into greatly
Case, per 120 bottles of box installed；
Step (6), the qualified storage of product laboratory detection.
Comparative example 1
It is a kind of to treat dyspeptic Chinese medicine composition, include the material component of following parts by weight：2 parts of the membrane of a chicken's gizzard, dried orange peel
3 parts, 6 parts of leaf of Herba Apii graveolentis, 2 parts of Radix Paeoniae Alba, 1 part of the stem of noble dendrobium, 2 parts of hawthorn, 3 parts of Chinese Fevervine Herb, 4.5 parts of polished rice, 1.5 parts of leaf lettuce.
The above-mentioned dyspeptic Chinese medicine composition for the treatment of is tablet, and preparation method includes the following steps：
It is step (1), the membrane of a chicken's gizzard, dried orange peel, leaf of Herba Apii graveolentis, Radix Paeoniae Alba, the stem of noble dendrobium, hawthorn, Chinese Fevervine Herb, polished rice, lettuce leaf raw material is pre-
After processing, crushing is dried at normal temperatures, the said goods examine the qualified raw material the membrane of a chicken's gizzard, dried orange peel, leaf of Herba Apii graveolentis, Radix Paeoniae Alba, stone
Dry measure used in former times, hawthorn, Chinese Fevervine Herb, polished rice, leaf lettuce are matched by technology preparation carries out ultramicro grinding in crushing workshop using airslide disintegrating mill,
The stream pressure of airslide disintegrating mill is 600~8000kPa, and charging rate is 180~200rmin-1, grade frequency be 20~
30Hz, grinding time are 20~30min, obtain Ultramicro-powder, and Ultramicro-powder grain size is 10~60 μm after ultramicro grinding, property after crushing
Material electronic scale between weighing is weighed；Pretreatment of raw material include by the membrane of a chicken's gizzard, dried orange peel, leaf of Herba Apii graveolentis, Radix Paeoniae Alba, the stem of noble dendrobium, hawthorn,
Chinese Fevervine Herb, polished rice, leaf lettuce are impregnated in brine respectively, brine strength 5-10%, and cleaning is pulled out and dried in the air under rear room temperature
It is dry.
Step (2) is transmitted to groove profile compound department, workshop temperature the load weighted raw material in workshop is weighed by sterile transferring window
14 degree, humidity 30% are spent, raw material is launched in CH-200 mixing machines, incorporation time is 20-30 minutes, 20 revs/min, by work
Skill requires setting incorporation time, and material is released with stainless steel barrel；When mixing, it is passed through nitrogen, protects active ingredient.
Step (3), will mix raw material by sterile transferring window be transmitted to tabletting workshop carry out tabletting, tablet press machine model
ZPW-19B, 3.8 thousand Ns of tablet press machine pressure, loading 5mm, every 1 gram of net content check a net content in every 10 minutes,
Net content is asked to reach between 1.05-1.10 grams；
Step (4), every bottled 60 Chinese medicine composition tablets, seal, have sealed bottle being transmitted to outsourcing entrucking later
Between labelled, case；The bottle labelling that inner packing workshop is transmitted, label print the date of manufacture, post label and are packed into greatly
Case, per 120 bottles of box installed；
Step (6), the qualified storage of product laboratory detection.
Comparative example 2
It is a kind of to treat dyspeptic Chinese medicine composition, include the material component of following parts by weight：2 parts of the membrane of a chicken's gizzard, dried orange peel
3 parts, 6 parts of leaf of Herba Apii graveolentis, 2 parts of Radix Paeoniae Alba, 2 parts of hawthorn, 3 parts of Chinese Fevervine Herb, 4.5 parts of polished rice, 1.5 parts of leaf lettuce, 3.5 parts of egg oil.
The above-mentioned dyspeptic Chinese medicine composition for the treatment of is tablet, and preparation method includes the following steps：
Step (1), by the membrane of a chicken's gizzard, dried orange peel, leaf of Herba Apii graveolentis, Radix Paeoniae Alba, hawthorn, Chinese Fevervine Herb, polished rice, leaf lettuce pretreatment of raw material
Afterwards, crushing is dried at normal temperatures, the said goods examine the qualified raw material the membrane of a chicken's gizzard, dried orange peel, leaf of Herba Apii graveolentis, Radix Paeoniae Alba, hawthorn, chicken
Dung rattan, polished rice, leaf lettuce are matched by technology preparation is crushing workshop using airslide disintegrating mill progress ultramicro grinding, airslide disintegrating mill
Stream pressure be 600~8000kPa, charging rate be 180~200rmin-1, grade frequency is 20~30Hz, when crushing
Between be 20~30min, obtain Ultramicro-powder, Ultramicro-powder grain size is 10~60 μm after ultramicro grinding, and all materials are between weighing after crushing
Electronic scale is weighed；Pretreatment of raw material includes by the membrane of a chicken's gizzard, dried orange peel, leaf of Herba Apii graveolentis, Radix Paeoniae Alba, hawthorn, Chinese Fevervine Herb, polished rice, lettuce
Lettuce leaf is impregnated in brine respectively, brine strength 5-10%, and cleaning is pulled out and dried under rear room temperature.
Step (2) prepares egg oil：Yolk will be left after the cooked son of egg, yolk grinding lets off pot after becoming powder
In plus water infusion, until there is egg oil, the volume ratio of yolk powder and water is 1:2-4
Step (3) is transmitted to groove profile compound department, workshop temperature the load weighted raw material in workshop is weighed by sterile transferring window
14 degree, humidity 30% are spent, raw material and egg oil dispensing in CH-200 mixing machines, incorporation time is 20-30 minutes, 20 turns/
Point, incorporation time is set by technological requirement, material is released with stainless steel barrel；When mixing, it is passed through nitrogen, protects active ingredient.
Step (4), will mix raw material by sterile transferring window be transmitted to tabletting workshop carry out tabletting, tablet press machine model
ZPW-19B, 3.8 thousand Ns of tablet press machine pressure, loading 5mm, every 1 gram of net content check a net content in every 10 minutes,
Net content is asked to reach between 1.05-1.10 grams；
Step (5), every bottled 60 Chinese medicine composition tablets, seal, have sealed bottle being transmitted to outsourcing entrucking later
Between labelled, case；The bottle labelling that inner packing workshop is transmitted, label print the date of manufacture, post label and are packed into greatly
Case, per 120 bottles of box installed；
Step (6), the qualified storage of product laboratory detection.
Comparative example 3
It is a kind of to treat unlike dyspeptic Chinese medicine composition and embodiment 2, include the raw material group of following parts by weight
Part：2 parts of the membrane of a chicken's gizzard, 3 parts of dried orange peel, 6 parts of leaf of Herba Apii graveolentis, 4 parts of Radix Paeoniae Alba, 1 part of the stem of noble dendrobium, 2 parts of hawthorn, 3 parts of Chinese Fevervine Herb, 4.5 parts of polished rice,
3.5 parts of 1.5 parts of leaf lettuce, egg oil
Comparative example 4
It is a kind of to treat unlike dyspeptic Chinese medicine composition and embodiment 2, include the raw material group of following parts by weight
Part：2 parts of the membrane of a chicken's gizzard, 3 parts of dried orange peel, 6 parts of leaf of Herba Apii graveolentis, 2 parts of Radix Paeoniae Alba, 1 part of the stem of noble dendrobium, 2 parts of hawthorn, 1 part of Chinese Fevervine Herb, 4.5 parts of polished rice,
1.5 parts of leaf lettuce, 3.5 parts of egg oil.
(1) animal acute toxicity test is carried out to tablet prepared by the present invention：
Drug：Raw material used in the present invention is commercially available from common Chinese shop, and specification meets national Chinese medicine standard.
Subjects：Small white mouse, weight is in 50g or so, male and female random selection.
Method and result：Small white mouse 10 is taken, it is 24 hours or so hungry, it feeds the application at twice daily by every and implements
Chinese medicine composition prepared by example 2,10 tablets once, continuous to feed after a week, observes 10 days, and mouse activity is normal, non-toxic reaction, nothing
Death shows the tablet of the present invention without acute toxicity, clinical medicine dose safety.
(2) long-term toxicity test for animals is carried out to tablet prepared by the present invention：
Experimental animal：Big white mouse, weight is in 120-130g, male and female random selection.
Method and result：Big white mouse 20 is taken, is divided into 2 groups, every group 10, wherein the 1st group is used as administration group, often by every
It feeds for it 2 times, 10 tablets once, and the 2nd group of diet as a control group, continuous 90 days, surveys weight, 24 after last time is administered
Hour sacrificed by decapitation surveys blood, routine urinalysis, liver function, renal function, the internal organ such as coring, kidney, the variation of tissues observed form, observation
The effect of dosage, observation diet, movable variation, experiments have shown that administration group is compared with the control group without significant changes, it is non-toxic
Reaction, is a kind of safe drugs.
Chinese medicine composition prepared by the application has carried out clinical test, and clinical criteria is as follows：
It cures：Sign and symptom improve completely, and diet is normal, and appetite is good；
It is effective：Sign and symptom significantly improve, and diet is normal, and appetite is preferable；
Effectively：Sign and symptom have change, and random thoughts are slightly uncomfortable, but can receive；
In vain：Symptom, sign are compared with pre-treatment without any change after treatment；
1) clinical diagnosis：Do not feel like eating, gasteremphraxis have the symptoms such as feeling of pain, indigestion.
2) in order to verify clinical efficacy, the application has carried out clinic trial, under the premise of the principle of voluntariness, randomly selects it
In 320 patients, and be randomly divided into eight groups, every group of 40 people.
3) therapy：Every group take respectively treatment prepared by the present embodiment 1-4 and comparative example 1-4 it is dyspeptic in
Drug composition tablet three times a day ten every time, is taken, 5 days as a treatment course, six courses for the treatment of totally after the meal.
4) efficacy determination：
Specific treatment results are referring to table 1.
It takes one week after terminating six courses for the treatment of and (carries out normal diet in one week, but excessively greasy food cannot be eaten
Object) it is counted, situation see the table below shown in 1, illustrate that the application treats dyspeptic Chinese medicine composition and has apparent treatment
Dyspeptic effect.
1 personal patient information of table and curative effect situation
By above-mentioned data in table 1 it is found that after the Chinese medicine composition for taking the present invention, effective percentage maintains
92.5%-97.5%, wherein cure rate maintain 90%-95%.Comparative example 1-4 since ingredient or content are adjusted,
Effective percentage only maintains 30%-47.5%, and wherein cure rate is only up to 12.5%.
Data above further illustrates that the present invention has apparent therapeutic effect for dyspeptic symptom, according to treatment
After journey is taken, indigestion symptom can be cured, will not be recurred in a short time.In addition the raw material type of the application is few, is pure natural
Drug securely and reliably has no toxic side effect, and selected medicinal material compatibility is suitable, meets traditional Chinese medicine and pharmacy and modern medical theory, according to monarch
Minister helps the combination principle made, reaches unexpected therapeutic effect, using convenient source, convenient for materials, cheap, preparation side
Method is simple.
It should be noted that the above embodiments are only used to illustrate the technical solution of the present invention., rather than its limitations；Although
Present invention has been described in detail with reference to the aforementioned embodiments, it will be understood by those of ordinary skill in the art that：It is still
Either which part or all technical features can be carried out so that technical scheme described in the above embodiments is modified
Equivalent replacement；And these modifications or replacements, it does not separate the essence of the corresponding technical solution various embodiments of the present invention technical side
The range of case.
Claims (9)
1. a kind for the treatment of dyspeptic Chinese medicine composition, it is characterized in that：Include the material component of following parts by weight：The membrane of a chicken's gizzard 1-
3 parts, 2-4 parts of dried orange peel, 5-8 parts of leaf of Herba Apii graveolentis, 1-3 parts of Radix Paeoniae Alba, 0.5-2 parts of the stem of noble dendrobium, 1.5-3 parts of hawthorn, 2-4 parts of Chinese Fevervine Herb, polished rice
3-6 parts, 1-2 parts of leaf lettuce, 2-5 parts of egg oil.
2. a kind of as described in claim 1 treat dyspeptic Chinese medicine composition and preparation method thereof, it is characterised in that：Packet
Material component containing following parts by weight：1 part of the membrane of a chicken's gizzard, 2 parts of dried orange peel, 5 parts of leaf of Herba Apii graveolentis, 1 part of Radix Paeoniae Alba, 0.5 part of the stem of noble dendrobium, hawthorn 1.5
Part, 2 parts of Chinese Fevervine Herb, 3 parts of polished rice, 1 part of leaf lettuce, 2 parts of egg oil.
3. a kind of as described in claim 1 treat dyspeptic Chinese medicine composition and preparation method thereof, it is characterised in that：Packet
Material component containing following parts by weight：2 parts of the membrane of a chicken's gizzard, 3 parts of dried orange peel, 6 parts of leaf of Herba Apii graveolentis, 2 parts of Radix Paeoniae Alba, 1 part of the stem of noble dendrobium, 2 parts of hawthorn, chicken
3 parts of dung rattan, 4.5 parts of polished rice, 1.5 parts of leaf lettuce, 3.5 parts of egg oil.
4. a kind of as described in claim 1 treat dyspeptic Chinese medicine composition and preparation method thereof, it is characterised in that：Packet
Material component containing following parts by weight：2.5 parts of the membrane of a chicken's gizzard, 3.5 parts of dried orange peel, 7 parts of leaf of Herba Apii graveolentis, 2.5 parts of Radix Paeoniae Alba, 1.5 parts of the stem of noble dendrobium, mountain
2.5 parts of short, bristly hair or beard, 3.5 parts of Chinese Fevervine Herb, 5 parts of polished rice, 2 parts of leaf lettuce, 4 parts of egg oil.
5. a kind of as described in claim 1 treat dyspeptic Chinese medicine composition, it is characterised in that：The treatment digestion is not
The dosage form of good Chinese medicine composition is powder, pulvis, tablet, granule, decoction, oral solution, honey ointment body, honeydew, beverage or tea
Pack any one in agent.
6. the preparation method of the dyspeptic Chinese medicine composition for the treatment of as described in any one of claim 1-5, treatment digestion
Undesirable Chinese medicine composition is tablet, it is characterised in that：Preparation method includes the following steps：
(1) by after the membrane of a chicken's gizzard, dried orange peel, leaf of Herba Apii graveolentis, Radix Paeoniae Alba, the stem of noble dendrobium, hawthorn, Chinese Fevervine Herb, polished rice, leaf lettuce feedstock processing by matching
Than after crushing workshop and crushing, weighing；
(2) mixes load weighted raw material and egg oil in step (1) in mixing machine, setting incorporation time, rotating speed,
Raw material is released after mixing；
(3) raw material mixed is carried out tabletting by using tablet press machine；
(4) it is packed after tablettings, after the completion of packaging, the qualified storage of product laboratory detection.
7. a kind of preparation method for treating dyspeptic Chinese medicine composition as claimed in claim 6, it is characterised in that：It is described
It needs to examine the membrane of a chicken's gizzard, dried orange peel, leaf of Herba Apii graveolentis, Radix Paeoniae Alba, the stem of noble dendrobium, hawthorn, Chinese Fevervine Herb, polished rice, leaf lettuce before step (1) sieving
It tests, is crushing workshop ultramicro grinding according to the ratio after the assay was approved.
8. a kind of preparation method for treating dyspeptic Chinese medicine composition as claimed in claim 6, it is characterised in that：It is described
It is ultramicro grinding that step (1), which crushes, and Ultramicro-powder grain size is 10~60 μm after ultramicro grinding.
9. a kind of preparation method for treating dyspeptic Chinese medicine composition as claimed in claim 6, it is characterised in that：It is described
The preparation method of step (2) mesolecithal oil is：Yolk will be left after the cooked son of egg, yolk grinding lets off pot after becoming powder
In plus water infusion, until there is egg oil.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810638905.XA CN108721522A (en) | 2018-06-20 | 2018-06-20 | It is a kind of to treat dyspeptic Chinese medicine composition and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810638905.XA CN108721522A (en) | 2018-06-20 | 2018-06-20 | It is a kind of to treat dyspeptic Chinese medicine composition and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108721522A true CN108721522A (en) | 2018-11-02 |
Family
ID=63930093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810638905.XA Pending CN108721522A (en) | 2018-06-20 | 2018-06-20 | It is a kind of to treat dyspeptic Chinese medicine composition and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108721522A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101721667A (en) * | 2008-10-29 | 2010-06-09 | 刘海松 | Traditional Chinese medicine for treating indigestion |
-
2018
- 2018-06-20 CN CN201810638905.XA patent/CN108721522A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101721667A (en) * | 2008-10-29 | 2010-06-09 | 刘海松 | Traditional Chinese medicine for treating indigestion |
Non-Patent Citations (3)
| Title |
|---|
| 李谦 等编: "《妇儿疾病单味良方》", 30 November 1998, 人民卫生出版社 * |
| 欧阳卫权: "脾宜健，肝宜疏，胃宜和", 《河南中医》 * |
| 田晓燕 等主编: "《让孩子不发烧、不咳嗽、不积食》", 31 August 2015, 江西科学技术出版社 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103652361B (en) | Feed for postpartum sow in lactation period of 1-20 days and preparation method thereof | |
| CN102511869B (en) | Thickened red jujube ginger pulp | |
| CN103355544B (en) | Lactation sow forage | |
| CN104873763A (en) | Health-care product for conditioning Qi deficiency constitution | |
| CN103690919B (en) | Medicine being used for the treatment of piglet iron-deficiency anemia and preparation method thereof | |
| CN110327421A (en) | A kind of suitable astronaut has the composition of raising energy and coordination each organ dysfunction of human body | |
| CN103689559A (en) | Health-preserving health food formula beneficial for improving gastrointestinal functions and preparation method thereof | |
| CN110214902A (en) | A kind of children's correction partial eclipse type selenium-rich complete nourishing powder | |
| TW202330006A (en) | Composition for preventing, improving or alleviating symptoms relating to qi deficiency and/or blood deficiency | |
| CN1142785C (en) | Antifatigue capsule | |
| CN106822660A (en) | A kind of Chinese medicine preparation for treating cardiovascular and cerebrovascular disease | |
| CN103416461A (en) | Healthy food capable of preventing and curing gastric ulcer and duodenal ulcer | |
| CN106860814A (en) | A kind of improvement women frequent micturition, health-care food composition of the urinary incontinence and its preparation method and application | |
| CN108721522A (en) | It is a kind of to treat dyspeptic Chinese medicine composition and preparation method thereof | |
| CN102671058B (en) | Traditional Chinese medicine oral liquid for treatment of vomiting and preparation method thereof | |
| CN110236035A (en) | A kind of Wolfberry hawthron health care magma and its application | |
| CN108967757A (en) | A kind of thickened red jujube ginger pulp production technology | |
| CN108785564A (en) | A kind of Chinese yam, dangshen product and preparation method thereof | |
| CN106620397A (en) | Granules capable of preventing and treating dental ulcer and preparation method of granules | |
| CN102423071B (en) | Food therapy bag | |
| CN101229331B (en) | Medicine for treating anorexia, limosis and preparing method thereof | |
| CN106359737A (en) | Honey black tea and making method thereof | |
| CN107281356B (en) | Stomach nourishing preparation and its preparation method | |
| KR20020078554A (en) | Essence manufacturing method based on seaweed and herbal medicine | |
| CN104707030A (en) | Traditional Chinese medicine pills for treating esophageal cancer and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20181102 |