CN108779159B - 具有经改造的angptl8基因的非人动物 - Google Patents
具有经改造的angptl8基因的非人动物 Download PDFInfo
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- CN108779159B CN108779159B CN201780015045.8A CN201780015045A CN108779159B CN 108779159 B CN108779159 B CN 108779159B CN 201780015045 A CN201780015045 A CN 201780015045A CN 108779159 B CN108779159 B CN 108779159B
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| EP3585162B1 (en) | 2017-09-29 | 2023-08-30 | Regeneron Pharmaceuticals, Inc. | Rodents comprising a humanized ttr locus and methods of use |
| HUE067361T2 (hu) | 2018-07-16 | 2024-10-28 | Regeneron Pharma | Ditra betegség rágcsáló modelljei és alkalmazásaik |
| AU2020253532B2 (en) | 2019-04-04 | 2024-06-20 | Regeneron Pharmaceuticals, Inc. | Non-human animals comprising a humanized coagulation factor 12 locus |
| WO2020247452A1 (en) | 2019-06-04 | 2020-12-10 | Regeneron Pharmaceuticals, Inc. | Non-human animals comprising a humanized ttr locus with a beta-slip mutation and methods of use |
| SG11202111256XA (en) | 2019-06-07 | 2021-11-29 | Regeneron Pharma | Non-human animals comprising a humanized albumin locus |
| CN114671943B (zh) * | 2022-04-29 | 2023-05-05 | 四川大学 | 一种鱼类摄食调控蛋白的制备和应用 |
| CN119367545B (zh) * | 2025-01-02 | 2025-04-08 | 山东第一医科大学(山东省医学科学院) | 靶向干预ANGPTL8 mRNA在制备治疗高同型半胱氨酸血症药物中的应用 |
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| CN108779159A (zh) | 2018-11-09 |
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| CA3012693A1 (en) | 2017-08-10 |
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| MA43962A (fr) | 2018-12-12 |
| SG11201806176PA (en) | 2018-08-30 |
| JP2019505216A (ja) | 2019-02-28 |
| JP6843872B2 (ja) | 2021-03-17 |
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