CN108771081A - Haematococcus pluvialis citrus fruit fibres compound solid beverage of weight-reducing and preparation method thereof - Google Patents

Haematococcus pluvialis citrus fruit fibres compound solid beverage of weight-reducing and preparation method thereof Download PDF

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Publication number
CN108771081A
CN108771081A CN201810661130.8A CN201810661130A CN108771081A CN 108771081 A CN108771081 A CN 108771081A CN 201810661130 A CN201810661130 A CN 201810661130A CN 108771081 A CN108771081 A CN 108771081A
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parts
powder
weight
haematococcus pluvialis
reducing
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王晶辉
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Beijing Beifred Health Technology Co ltd
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Tianjin Bei Fei Rui De Biotechnology Co Ltd
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/385—Concentrates of non-alcoholic beverages
    • A23L2/39—Dry compositions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A23L2/60—Sweeteners
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A23L2/68—Acidifying substances
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
    • A23L33/25—Synthetic polymers, e.g. vinylic or acrylic polymers
    • A23L33/26—Polyol polyesters, e.g. sucrose polyesters; Synthetic sugar polymers, e.g. polydextrose
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The present invention discloses a kind of complex solid plant beverage of weight-reducing and preparation method thereof.The complex solid plant beverage includes citrus fruit fibres, apple fiber, Semen Tritici aestivi fiber, konjaku flour, fruits and vegetables composite ferment powder, orange fruit powder, polydextrose, green cumquat powder, pineapple powder, citric acid, beta carotene, Opuntia ficus' fruit powder, orange blossom powder, haematococcus pluvialis, L-carnitine-L-tartrate, conjugated linoleic acid glyceride, radix polygonati officinalis powder, lutein, Sucralose, food flavor.The present invention does not injure gastrointestinal tract while capable of losing weight, and can improve human-body sub-health, improves intestinal flora environment, is beneficial to intestinal movement, builds up health.

Description

Haematococcus pluvialis citrus fruit fibres compound solid beverage of weight-reducing and preparation method thereof
Technical field
The present invention relates to plant beverage technical fields, and in particular to a kind of haematococcus pluvialis citrus fruit fibres of weight-reducing are compound Solid beverage and preparation method thereof.
Background technology
With the variation of resident living mode and dietary structure in recent years, fat illness rate is in rapid increase trend, fertilizer It is fat to have become one of the serious public health problem faced.Obesity, diabetes, hypertension and angiocardiopathy have become prestige Coerce the greatest danger factor of health of people.Wherein, fat is mainly luring for the slow disease such as diabetes, hypertension, angiocardiopathy again One of because, it is seen that problem of obesity has risen to as the main problem of relationship resident's publilc health.
Have antiobesity action on the market at present is drug or health food mostly, can add various chemical substances to reach Mode to control appetite, the consumption energy such as diarrhea loses weight, and long term usage can cause gastrointestinal bacterial flora disorder, functional disturbance, right Body has very big damage.
Such as：CN201710050144.1 discloses a kind of meal replacement powder with fat reducing weight losing function, including following component：Essence 10-20 parts of oat bran powder processed；20-30 parts of wheat bran powder；3-6 parts of palm oil powder；10-20 parts of PURE WHEY；Aqueous soluble dietary 5-10 parts of fiber；0.05-0.5 parts of sweetener；0.1-0.5 parts of fragrance, after all raw materials are poured into batch mixer mixing 10-20 minutes Spray drying is to get the meal replacement powder with fat reducing weight losing function.The refined oat bran powder of pure Physical Processing of the present invention is not only substantially Raw starch content is reduced, feature low in calories is made it have, and increases the nutrition of vitamin, minerals and protein Density, and the oat beta glucan rich in natural structure.It is different from oat beta glucan prepared by biological enzymolysis technology, refine swallow Oat beta glucan remains natural macromolecular structure in wheat bran.It is reached in natural structure oat beta glucan of the human body per canteen When to 3 grams or more, in human gastrointestinal tract that the food for forming very high viscosity is rotten, this not only adds human body satieties, more attach most importance to What is wanted is the absorption for substantially slowing down and reducing sugar and fat, so that human body postprandial blood sugar is effectively controlled, plays low glycemic The important function of diet.Physiologic theory shows the secretion of elevated blood glucose levels stimulation insulin, and insulin, which has, promotes fat to close At effect, to fat reducing, weight-reducing it is unfavorable.Therefore, people to lose weight needs, by low glycemic diet, to reduce postprandial insulin levels, To promote the decomposition of fat, the purpose of fat reducing and weight-reducing is realized.
CN201210133677.3 discloses a kind of fat-reducing nutrient stick and its from Preparation Method, and formula composition is soybean separation protein White swelling granular 20%~50%；Maltitol liquor 15%~30%；Water-soluble dietary fiber 8%~25%；Condensed whey egg White 1%~8%；Glycerine 1%~8%；Isin glue collagen 1%~8%；Phytosterol 1%~2%；Quick-frozen blueberry grain 1%~ 4%；Arabic gum 0.5%~3%；Casein sodium 0.5%~2%；Multi-vitamins 0.03%~0.12%.The invention carries A kind of nutrition-balanced diet food has been supplied, following component is contained：Soybean protein isolate swelling granular；Maltitol liquor；It is water-soluble Property dietary fiber；Whey protein concentrate；Glycerine；Isin glue collagen；Phytosterol；Quick-frozen blueberry grain；Arabic gum；Caseinic acid Sodium；Multi-vitamins.The fat-reducing nutrient stick is in good taste, and protein content is high, there is enhancing satiety can supplement protein again, simultaneously It is added to the functional food ingredients such as Isin glue collagen, phytosterol and multi-vitamins etc. again, so that consumer is reached health and subtracts The purpose of fertilizer.
Invention content
In view of the technical drawbacks of the prior art, it is an object of the present invention to provide a kind of rain of weight-reducing to give birth to red ball Algae citrus fruit fibres compound solid beverage and preparation method thereof.
The technical solution adopted to achieve the purpose of the present invention is：
A kind of haematococcus pluvialis citrus fruit fibres compound solid beverage of weight-reducing, by weight, including：
300-800 parts of citrus fruit fibres, 300-800 parts of apple fiber, 300-800 parts of Semen Tritici aestivi fiber, konjaku flour 500-1500 Part, 1000-2500 parts of fruits and vegetables composite ferment powder, 300-800 parts of orange fruit powder, 200-500 parts of polydextrose, green cumquat powder 100- 300 parts, 100-300 parts of pineapple powder, 100-300 parts of citric acid, 100-300 parts of beta carotene, Opuntia ficus' fruit powder 5-15 Part, 5-15 parts of orange blossom powder (French citrus polyphenol), 5-15 parts of haematococcus pluvialis, 30-80 parts of L-carnitine-L-tartrate, conjugation 30-80 parts of glyceryl linoleate, 20-80 parts of radix polygonati officinalis powder, 5-15 parts of lutein (10%), 5-20 parts of Sucralose, food flavor 20-48 parts of (orange taste).
A kind of preparation method of the haematococcus pluvialis citrus fruit fibres compound solid beverage of weight-reducing, includes the following steps：
Load weighted Opuntia ficus' fruit powder, orange blossom powder, haematococcus pluvialis, L-carnitine-L-tartrate, conjugation is sub- Olein, radix polygonati officinalis powder, lutein, Sucralose, food flavor mix 60 minutes, remaining load weighted raw material is then added 60 minutes are remixed to get finished product.
In the prescription of the present invention, l-cn is a kind of amino acid promoting adipose conversion as energy, nontoxic to human body Side effect, particularly suitable people's cooperation does aerobic exercise and carrys out fat reducing, while reducing the triglyceride in blood and cholesterol levels, Also fat extra in incendivity body can lose weight as energy, reduce the content of body fat, have antiobesity action； Conjugated linoleic acid glyceride is the pure natural active factor of the health type of latest find in the world, can play alleviate fatty liver, The effect of weight-reducing, and hyperlipidemia, the state of an illness of diabetic can be controlled；Haematococcus pluvialis is acknowledged as producing day in nature The best biology of right astaxanthin, is rich in astaxanthin, and astaxanthin is strongest natural in nature, has anti-aging, Immunity is improved, has inhibiting effect to inflammation, and the good results are evident；Haematococcus pluvialis is arranged in pairs or groups radix polygonati officinalis powder, lutein simultaneously, is used To build up resistance, eliminate the inflammation of parts of body, alleviation sub-health state；This product is with the original with effect of weight reducing When material, arrange in pairs or groups various raw fiber food raw materials and fruit powder：Citrus fruit fibres, apple fiber part, Semen Tritici aestivi fiber, konjaku flour part, fruits and vegetables Composite ferment powder, orange fruit powder, polydextrose, green cumquat powder, pineapple powder, beta carotene, Opuntia ficus' fruit powder, orange blossom Powder improves the bad habit of constipation, achievees the purpose that defaecation, add simultaneously for improving gastrointestinal bacterial flora and increasing intestines peristalsis Add corrigent citric acid, Sucralose, food flavor, is this product sweet and sour taste, convenient for being esthetically acceptable to the consumers.It is former used in this product Material be natural food material source, it is without any side effects, be suitble to long-term consumption, for improve with hypoimmunity, constipation, Inferior health caused by fat, various inflammation.
The present invention does not injure gastrointestinal tract while capable of losing weight, and can improve human-body sub-health, improves intestinal flora environment, has Beneficial to intestinal movement, build up health.
Specific implementation mode
Embodiment 1
The haematococcus pluvialis citrus fruit fibres compound solid beverage of weight-reducing, by weight, including：
300 parts of citrus fruit fibres, 300 parts of apple fiber, 300 parts of Semen Tritici aestivi fiber, 500 parts of konjaku flour, fruits and vegetables composite ferment powder 1000 parts, 300 parts of orange fruit powder, 200 parts of polydextrose, green 100 parts of cumquat powder, 100 parts of pineapple powder, 100 parts of citric acid, β-Hu It is 100 parts of radish element, 5-15 parts of Opuntia ficus' fruit powder, 5 parts of orange blossom powder (French citrus polyphenol), 5 parts of haematococcus pluvialis, left-handed 30 parts of carnitine tartrate, 30 parts of conjugated linoleic acid glyceride, 20 parts of radix polygonati officinalis powder, (10%) 5 part of lutein, 5 parts of Sucralose, 20 parts of food flavor (orange taste).
Embodiment 2
The haematococcus pluvialis citrus fruit fibres compound solid beverage of weight-reducing, by weight, including：
800 parts of citrus fruit fibres, 800 parts of apple fiber, 800 parts of Semen Tritici aestivi fiber, 1500 parts of konjaku flour, fruits and vegetables composite ferment powder 2500 parts, 800 parts of orange fruit powder, 500 parts of polydextrose, green 300 parts of cumquat powder, 300 parts of pineapple powder, 300 parts of citric acid, β-Hu It is 300 parts of radish element, 15 parts of Opuntia ficus' fruit powder, 15 parts of orange blossom powder (French citrus polyphenol), 15 parts of haematococcus pluvialis, left-handed 80 parts of carnitine tartrate, 80 parts of conjugated linoleic acid glyceride, 80 parts of radix polygonati officinalis powder, (10%) 15 part of lutein, Sucralose 20 Part, 48 parts of food flavor (orange taste).
Embodiment 3
The haematococcus pluvialis citrus fruit fibres compound solid beverage of weight-reducing, by weight, including：
550 parts of citrus fruit fibres, 550 parts of apple fiber, 550 parts of Semen Tritici aestivi fiber, 1000 parts of konjaku flour, fruits and vegetables composite ferment powder 1750 parts, 550 parts of orange fruit powder, 350 parts of polydextrose, green 200 parts of cumquat powder, 200 parts of pineapple powder, 200 parts of citric acid, β-Hu 200 parts of radish element, 10 parts of Opuntia ficus' fruit powder, orange blossom powder (10 parts of French citrus polyphenol, 10 parts of haematococcus pluvialis, left-handed meat 40 parts of alkali tartrate, 40 parts of conjugated linoleic acid glyceride, 50 parts of radix polygonati officinalis powder, (10%) 10 part of lutein, 13 parts of Sucralose, 34 parts of food flavor (orange taste).
Embodiment 4
The haematococcus pluvialis citrus fruit fibres compound solid beverage of weight-reducing, by weight, including：
500 parts of citrus fruit fibres, 500 parts of apple fiber, 500 parts of Semen Tritici aestivi fiber, 1000 parts of konjaku flour, fruits and vegetables composite ferment powder 1500 parts, 500 parts of orange fruit powder, 300 parts of polydextrose, green 200 parts of cumquat powder, 200 parts of pineapple powder, 200 parts of citric acid, β-Hu 200 parts of radish element, 10 parts of Opuntia ficus' fruit powder, orange blossom powder (10 parts of French citrus polyphenol, 10 parts of haematococcus pluvialis, left-handed meat 50 parts of alkali tartrate, 50 parts of conjugated linoleic acid glyceride, 60 parts of radix polygonati officinalis powder, (10%) 10 part of lutein, 15 parts of Sucralose, 28 parts of food flavor (orange taste).
The preparation method of the haematococcus pluvialis citrus fruit fibres compound solid beverage of the weight-reducing of the various embodiments described above, including with Lower step：
By Opuntia ficus' fruit powder of 80 mesh of load weighted mistake sieve, orange blossom powder, haematococcus pluvialis, L-Carnitine tartrate Salt, conjugated linoleic acid glyceride, radix polygonati officinalis powder, lutein, Sucralose, food flavor mix 60 minutes, remaining is then added and claims The raw material of 80 mesh of measured mistake sieve remixes 60 minutes to get finished product, then bag distribution packaging.
Pharmacy test：
Animal experiment
1. materials and methods
1.1 animal：
Cleaning grade male SD rat 60,6~8 week old, 160~200g of weight are provided by Zhejiang Province's Experimental Animal Center, Animal credit number SCXK (Zhejiang) 2014-0001.20~25 DEG C of feeding environment temperature, humidity 40%~60%, 12h/12h light Bright/dark condition.
1.2 drugs and reagent：
Experiment is with sample using the haematococcus pluvialis citrus fruit fibres compound solid beverage prepared by embodiment 3；Orlistat (Haizheng Medicine Stock Co., Ltd., Zhejiang Prov, 15051901)；High glucose and high fat feed (Zhejiang Province's Experimental Animal Center)；ELISA is examined Test agent box (is purchased from the Shanghai bio tech ltd Yuan Ye, E20160301A)；Eosin stain, haematoxylin dye liquor (Nanjing Build up Science and Technology Ltd., 20151216).Healthy adult female BAl BIc/C mice, 18~22g of weight, Huaxi Medical Univ's examination It tests animal center and (quality certification number is provided：Guan Zhi 64 is moved in fact in river).
1.3 method
1.3.1 the preparation and grouping of obese model：60 male SD rat adaptable feds are after 1 week, wherein 50 feedings High glucose and high fat feed prepares DIO models, and another 10 are only used as normal group, give chow diet.During modeling, each group rat freely drinks Water is ingested.It is more than the 10% of normal rats weight to be used as obesity standard after modeling 8 weeks, using weight, chooses 40 modelings successfully DIO rats, continue to give high glucose and high fat feed.It is randomly divided into model group according to weight, orlistat group (32.4mg/kg), Haematococcus pluvialis citrus fruit fibres compound solid beverage high dose group (200mg/kg), haematococcus pluvialis citrus fruit fibres complex solid drink Material low dose group (100mg/kg), every group 10.Gavage gives relative medicine respectively, continuous 13 weeks, administered volume 10mL/kg, 0.4% carboxymethylcellulose sodium solution of model group and normal group gavage equivalent.
1.3.2 weight, food ration, amount of drinking water and Lee's indexes：Experiment terminates first 1 day, measures each group Rat 24 h drink Water, food ration.After the last administration, weight, body length (length of nose to anus) are measured, Lee's indexes Index is calculated.It calculates Formula is as follows：Lee's indexes=(weight × 1000) ^ (1/3)/body length (cm).
1.3.3 liver body when fat body ratio：After rat is put to death, separation liver, kidney week and testis week fat are simultaneously weighed, and liver body is calculated When fat body ratio.Calculation formula is as follows：Liver body ratio=liver mass (mg)/weight (g) × 100%；Fat body ratio=(kidney week or testis Week) fat mass (mg)/weight (g) × 100%；Total fat body ratio=(kidney week+testis week) fat mass (mg)/weight (g) × 100%.
1.3.4 the comparison of fatty pathological section：Take the same position of testis week fat, 10% formalin fixes, ethanol dehydration, Dimethylbenzene is transparent, paraffin embedding, be sliced, 5 μm of paraffin sections, microscopically observation after HE dyeing is made.
1.3.5 statistical procedures：Experimental data is indicated using x ± s, and statistical analysis is carried out using 16.0 softwares of SPSS, Statistical method is one-way analysis of variance (One-wayANOVA).P < 0.05 or P < 0.01 indicate statistically significant.
2 results
The influence of 2.1 pairs of rat body weights, food ration, amount of drinking water and Lee's indexes：Compared with normal group, rat model body Weight, Lee's indexes increase (P < 0.01)；Compared with model group, 2 dosage of haematococcus pluvialis citrus fruit fibres compound solid beverage Group rat body weight, Lee's indexes are decreased obviously (P < 0.05)；And food ration, amount of drinking water is shown in Table 1 then without significant change, right The influence (x ± s, n=10) of DIO rat body weights, food ration, amount of drinking water and Lee's indexes.
Table 1
Note:The * P < 0.01 compared with normal group；The * * P < 0.05 compared with model group, * * * P < 0.01.
2.2 pairs of rat fat bodies when liver body than influence：Compared with normal group, rat model kidney fat body ratio, testis fat body ratio, Total fat body when liver body
Than raising (P < 0.01)；Compared with model group, 2 dosage groups of haematococcus pluvialis citrus fruit fibres compound solid beverage Rat renal fat body ratio, testis fat body ratio are decreased obviously (P < 0.05)；The total fat body of high dose group is than declining；And 2 dosage group liver bodies Than having no significant change, be shown in Table 2, to DIO rat fat body when liver body than influence (x ± s, n=10)；
Table 2
Note:The * P < 0.01 compared with normal group；The * * P < 0.05 compared with model group, * * * P < 0.01
The influence of 2.3 pairs of rat testis week adipose tissue pathology variations：HE dyeing displays, after being administered 13 weeks, normal rat fat Fat cell arrangement is close, and cell edges are clear；Rat model adipocyte volume significantly increases (P < compared to normal group 0.01), and cell edges are fuzzy, and cellular morphology is irregular, imperfect.Compared with model group, 2 dosage groups can be in various degree Reduction adipocyte volume (P < 0.01), significantly improve cellular morphology.
3 analyses
This experiment continuously feeds modeling in 8 weeks, the bad life not saved close to mankind's diet using high glucose and high fat feed Custom, while meeting theory of traditional Chinese medical science to fat understanding.Obesity is mainly manifested in body fat accumulation excessively, and wherein testis week The content of fat and perirenal fat accounts for the certain proportion of total fat mass, thus commonly use this 2 indexs and they and it is with weight Ratio (fat body ratio) reflects Obesity；Meanwhile high glucose and high fat feed can lead to the accumulation of liver fat, so as to cause liver The increase of coefficient.And Lee's indexes are equivalent to the body-mass index (BMI) of people, are to evaluate having for adult rat obese degree Imitate index.The indexs synchronizations such as rat body weight, Lee's indexes, fat coefficient, liver coefficient are compared in this experiment, are more fully commented Valence weight-reducing drug effect.
The experimental results showed that compared with normal group, the weight of model group rats, Lee's indexes, kidney fat body ratio, testis fat body When total fat body ratio significantly rises, and prompts DIO obese model modelings success；Give haematococcus pluvialis citrus fruit fibres complex solid drink After expecting 13 weeks, the weight of haematococcus pluvialis citrus fruit fibres 2 dosage group rats of compound solid beverage, Lee's indexes, kidney fat body It is remarkably decreased than than, testis fat body；The total fat body of high dose group rat is than significantly reducing, haematococcus pluvialis citrus fruit fibres complex solid Beverage has the function of weight-reducing to DIO rats.Compared with model group, 2 agent of haematococcus pluvialis citrus fruit fibres compound solid beverage The food ration of amount group rat, the equal no significant difference of amount of drinking water prompt haematococcus pluvialis citrus fruit fibres compound solid beverage big to DIO The antiobesity action of mouse is generated by Anorectic effect Alcohol.
In conclusion haematococcus pluvialis citrus fruit fibres compound solid beverage DIO obese rats have certain antiobesity action, Mechanism of action may be related at fat differentiation, the reduction size of adipocyte to inhibition.
To haematococcus pluvialis citrus fruit fibres compound solid beverage prepared by other embodiments 1,2,4, above-mentioned side is equally used Method is tested, and has equally been achieved the effect that above-mentioned.
Clinical test：
1) general information：120 case clinical observations of the present inventor couple, wherein man 61, female 59；Age minimum 18 It is year, 60 years old maximum；Simple obesity 37, obesity merging blood fat and blood pressure is 49 high, hyperlipidemia, hypoimmunity 30, other 4 (including fat fatiguability person, obesity are susceptible to suffer from various inflammation etc. simultaneously).
2) therapy：Twice for each person every day, each 6g (beverage prepared by embodiment 3).
3) efficacy assessment standard：
It cures：Clinical symptoms completely disappear, and restore normal type.
Effectively：A weight loss part, remaining symptom disappear
In vain：Symptom, sign are without significant change.
4) treatment results：Treatment results such as the following table 3.
Total case It cures Effectively In vain It is efficient
120 86 28 6 95%
Table 3
120 are equally used to haematococcus pluvialis citrus fruit fibres compound solid beverage prepared by other embodiments 1,2,4 Case carries out clinical test, and effective percentage respectively reaches 90%, 93%, 91%.
5) typical clinical case：
1, Zhang, man, 21 years old, simple obesity in 2016, after taking this product 30 days, weight recovery to normal level.
2, Qi, female, 41 years old, Hyperlipidemia in 2017, fat, after taking this product 28 days, blood fat was normal, and weight loss is extremely Normal level.
3, Zhang, man, 49 years old, blood fat and blood pressure height, obesity, immunity degradation in 2017, after taking this product 30 days, recovery from illness.
4, Lee, man, 59 years old, blood fat and blood pressure height, obesity, immunity degradation in 2016, after taking this product 35 days, fully recovered
5, money, female, 40 years old, blood fat and blood pressure height, obesity, immunity degradation in 2015, after taking this product 33 days, fully recovered
6, Wei, man, 35 years old, blood fat and blood pressure height, obesity, immunity degradation in 2016, after taking this product 30 days, recovery from illness.

Claims (2)

1. the haematococcus pluvialis citrus fruit fibres compound solid beverage of weight-reducing, which is characterized in that by weight, including：
300-800 parts of citrus fruit fibres, 300-800 parts of apple fiber, 300-800 parts of Semen Tritici aestivi fiber, 500-1500 parts of konjaku flour, fruit 1000-2500 parts of vegetable composite ferment powder, 300-800 parts of orange fruit powder, 200-500 parts of polydextrose, green cumquat powder 100-300 Part, 100-300 parts of pineapple powder, 100-300 parts of citric acid, 100-300 parts of beta carotene, 5-15 parts of Opuntia ficus' fruit powder, mandarin orange 5-15 parts of orange juice powder, 5-15 parts of haematococcus pluvialis, 30-80 parts of L-carnitine-L-tartrate, conjugated linoleic acid glyceride 30-80 Part, 20-80 parts of radix polygonati officinalis powder, 5-15 parts of lutein, 5-20 parts of Sucralose, 20-48 parts of food flavor.
2. the preparation method of the haematococcus pluvialis citrus fruit fibres compound solid beverage of weight-reducing as described in claim 1, feature It is, includes the following steps：
By load weighted Opuntia ficus' fruit powder, orange blossom powder, haematococcus pluvialis, L-carnitine-L-tartrate, conjugated linoleic acid Glyceride, radix polygonati officinalis powder, lutein, Sucralose, food flavor mix 60 minutes, remaining load weighted raw material is then added and mixes again 60 minutes are closed to get finished product.
CN201810661130.8A 2018-06-25 2018-06-25 Haematococcus pluvialis citrus fruit fibres compound solid beverage of weight-reducing and preparation method thereof Pending CN108771081A (en)

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CN115989867A (en) * 2022-12-07 2023-04-21 广东金骏康生物技术有限公司 Citrus composition for losing weight and preparation method and application thereof

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CN105995976A (en) * 2016-05-19 2016-10-12 厦门元之道生物科技有限公司 Integrated enzyme powder having effects of reducing fat and losing weight and application thereof
CN106174182A (en) * 2016-07-12 2016-12-07 上海广得利保健食品有限公司 A kind of comprehensive vegetables and fruits composite powder
CN106509126A (en) * 2016-10-25 2017-03-22 郑州福润德食品有限公司 Solid drink having weight losing and body slimming functions
CN107307406A (en) * 2017-08-01 2017-11-03 王海军 A kind of weight-reducing tablet and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN103404827A (en) * 2013-07-08 2013-11-27 北京康比特体育科技股份有限公司 Seasoning capable of loosing weight
CN105995976A (en) * 2016-05-19 2016-10-12 厦门元之道生物科技有限公司 Integrated enzyme powder having effects of reducing fat and losing weight and application thereof
CN106174182A (en) * 2016-07-12 2016-12-07 上海广得利保健食品有限公司 A kind of comprehensive vegetables and fruits composite powder
CN106509126A (en) * 2016-10-25 2017-03-22 郑州福润德食品有限公司 Solid drink having weight losing and body slimming functions
CN107307406A (en) * 2017-08-01 2017-11-03 王海军 A kind of weight-reducing tablet and preparation method thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115989867A (en) * 2022-12-07 2023-04-21 广东金骏康生物技术有限公司 Citrus composition for losing weight and preparation method and application thereof

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