CN108743673A - Treat psoriasic black ointment itself and preparation method - Google Patents

Treat psoriasic black ointment itself and preparation method Download PDF

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CN108743673A
CN108743673A CN201810983304.2A CN201810983304A CN108743673A CN 108743673 A CN108743673 A CN 108743673A CN 201810983304 A CN201810983304 A CN 201810983304A CN 108743673 A CN108743673 A CN 108743673A
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parts
ointment
black
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honeysuckle
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谢允超
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Abstract

This application provides psoriasic black ointment itself and preparation method is treated, wherein black ointment includes the ingredient of following mass fraction：15-30 parts of indigo naturalis, 5-10 parts of borneol, 5-10 parts of talcum, 2-10 parts of the root of Dahurain angelica, 10-20 parts of radix scutellariae, 10-20 parts of Asian puccoon, 5-10 parts of gypsum, 6-15 parts of honeysuckle, 5-10 parts of Radix Notoginseng, 15-30 parts of Radix Angelicae Sinensis.The black ointment of the application also contains skin care, function promoting blood circulation and removing blood stasis other than clearing heat and detoxicating effect.It is pure Chinese medicinal preparation by black ointment prepared by the application preparation method, the scope of application is wider, child adult can be used.

Description

Treat psoriasic black ointment itself and preparation method
Technical field
The present invention relates to black ointment fields, and in particular to treats psoriasic black ointment itself and preparation method.
Background technology
Black ointment is a kind of drug, and primary efficacy enhances the permeability of local vessel, have warp for improving local circulation The priming effect of luo-connecting point moxibustion, activates histocyte, improves immune function, promotes rehabilitation.
Antipsoriatics cream probably belongs to antipyretic-detoxicant preparation, and single effect is poor to the improvement of skin, suitable Limited to range.
Invention content
The main purpose of the application be to provide it is a kind for the treatment of psoriasic black ointment itself and preparation method, to solve to treat Psoriasic ointment curative effect Single-issue.
To achieve the goals above, it according to the one side of the application, provides and a kind for the treatment of psoriasic black ointment.
The psoriasic black ointment for the treatment of according to the application includes the ingredient of following mass fraction：15-30 parts of indigo naturalis, borneol 5-10 parts, 5-10 parts of talcum, 2-10 parts of the root of Dahurain angelica, 10-20 parts of radix scutellariae, 10-20 parts of Asian puccoon, 5-10 parts of gypsum, honeysuckle 6-15 Part, 5-10 parts of Radix Notoginseng, 15-30 parts of Radix Angelicae Sinensis.
As improvement of the present invention, include the component of following mass parts：16-29 parts of indigo naturalis, 6-9 parts of borneol, talcum 6-9 Part, 3-9 parts of the root of Dahurain angelica, 11-19 parts of radix scutellariae, 11-19 parts of Asian puccoon, 6-9 parts of gypsum, 7-14 parts of honeysuckle, 6-9 parts of Radix Notoginseng, Radix Angelicae Sinensis 16-29 parts.
As improvement of the present invention, include the component of following mass parts：14.5-30.5 parts of indigo naturalis, borneol 4.5-10.5 Part, 5.5-10.5 parts of talcum, 2.5-9.5 parts of the root of Dahurain angelica, 10.5-19.5 parts of radix scutellariae, 10.5-19.5 parts of Asian puccoon, gypsum 5.5-9.5 Part, 6.5-14.5 parts of honeysuckle, 5.5-9.5 parts of Radix Notoginseng, 15.5-29.5 parts of Radix Angelicae Sinensis.
Indigo naturalis in the present invention, nature and flavor are salty-cold, there is clearing heat and detoxicating, blood cooling and ecchymoses removing, purging intense heat arresting convulsion and other effects.It is mainly used for temperature Sick excess heat, macula are spitted blood, spitting of blood, pharyngalgia aphtha, pediatric epilepsy scared, sore swells, erysipelas, snakebite and bugbite etc..
Borneol is the crisp crystallization of sheet of water white transparency or white translucent；Gas faint scent, it is acrid flavour, cool.Borneol acrid flavour, hardship, It is slightly cold；The thoughts of returning home, liver, lung channel；Delicate fragrance a surname dissipate has the effect of inducing resuscitation of having one's ideas straightened out, heat-clearing dissipates poison, removing nebula, cures mainly pyreticosis high fever Coma, apoplexy coma due to blocking of the respiratory system shies epilepsy, summer-heat and damp blinds clear key, throat deafness, aphtha tooth swells, sore carbuncle infantile malnutrition due to digestive disturbances or intestinalparasites hemorrhoid, red eye, swell pain, pterygium.
The root of Dahurain angelica, nature and flavor are acrid in flavour and warm in nature.Wind-dispelling, eliminating dampness are subsided a swelling, analgesic.Control headache, pain in the supra-orbital bone, dentalgia, nasosinusitis, cold-dampness abdomen Bitterly, intestines wind anal fistula, leukorrhea with reddish discharge, ulcer sores, skin itchy, mange.
Radix scutellariae, nature and flavor：Hardship is trembled with fear.Excess fire is rushed down, except damp and hot, hemostasis, tocolysis.Control high fever polydipsia, cough with lung heat, damp-heat dysentery, Jaundice, heat gonorrhea are spat, are defeated in battle, collapse, are leaked, red eye, swell pain, fetal irritability, carbuncle swells furunculosis.
Asian puccoon, nature and flavor：Hardship is trembled with fear.Major function：Cool blood, promoting blood circulation, heat-clearing, removing toxic substances.Warm macula is controlled, jaundice with damp-heat pathogen is purple Purplish or white patches on the skin spits, is defeated in battle, hematuria, stranguria with turbid discharge, constipation with heat retention, burn, eczema, erysipelas, large carbuncle.
Radix Notoginseng, nature and flavor：Sweet, slight bitter, temperature.For spitting blood, haematemesis, bleeding from five sense organs or subcutaneous tissue is had blood in stool, uterine bleeding, traumatic hemorrhage, chest and abdomen shouting pain, Tumbling and swelling.
Radix Angelicae Sinensis, nature and flavor：Sweet, pungent, temperature compensation blood；Promoting blood circulation；Menstruction regulating and pain relieving；Moisturize laxation.The main all cards of the deficiency of blood；Irregular menstruation；Through It closes；Dysmenorrhoea；Abdominal mass knot is poly-；Uterine bleeding；Asthenia cold abdominalgia；Impotence numbness；Numbness；Intestines are dry and shit is difficult；Weight after dysentery characterized by blood in the stool；Ulcer sores；Fall and flutters Damage.
Gypsum cures mainly apoplexy fever and chills, there is expelling pathogenic factors from muscles by diaphoresis, except dry tongue is burnt, the functions such as headache is had a toothache.
Talcum, it is sweet, light, it trembles with fear.Return bladder, lung, stomach.Inducing diuresis for treating strangurtia, clearing away summerheat, clearing damp sore.
The present invention leads to above-mentioned indigo naturalis, borneol, talcum, the root of Dahurain angelica, radix scutellariae, Asian puccoon, gypsum, honeysuckle, Radix Notoginseng, Radix Angelicae Sinensis It crosses certain ratio and black powder paste is made, ten kinds of above-mentioned drugs are combined, can not only make this ten kinds of drugs respectively Function can bring into play well, and by combining, unexpected effect except this ten kinds of drugs can be harvested, Experiments have shown that the black ointment obtained by the present invention, can not only also contain other than clearing heat and detoxicating effect and moisturize the skin, is living The function of blood stagnation resolvation, therefore other than it can solve the psoriasic dry symptom for itching furfur, moreover it is possible to the raw new work that goes to become silted up is generated to skin With it is advantageous that using the drug for invigorating blood circulation and eliminating stasis in Chinese medicine, promoting the plasma metabolism speed in subcutaneous capilary to increase, Jin Ergai Kind color spot, pigementation, the problem of colour of skin unevenness, due to being pure Chinese medicinal preparation, thus it is applied widely, child adult can feel at ease It uses.And in terms of existing technologies, the treatment course of the black ointment in the present invention is short, quick, cure rate is high, cures Effect is more preferable.
In addition, treat psoriasic black ointment also and can treat eczema, chronic eczema, one to two degree burn and scald, Atopic dermatitis, Fat leakage property dermatitis, pityriasis rosea sequelae, neurodermatitis, drug, ointment allergy, Lavender Extract, red, swollen, hot, pain, itch, Dry furfur of itching of bite by mosquitos, nettle rash, diaper rash, acne, wheal, skin etc..
Specific implementation mode
In order to make those skilled in the art more fully understand application scheme, below to the technology in the embodiment of the present application Scheme is clearly and completely described, it is clear that and described embodiment is only the embodiment of the application part, rather than Whole embodiments.Based on the embodiment in the application, those of ordinary skill in the art are not making creative work premise Lower obtained every other embodiment, shall fall within the protection scope of the present application.
It should be noted that the term " comprising " in the description and claims of this application and his any change Shape, it is intended that cover it is non-exclusive include, for example, the method for containing series of steps be not necessarily limited to clearly to list that A little steps, but may include other steps not listing clearly or for these methods inherently.
In the case of not conflicting, the features in the embodiments and the embodiments of the present application can be combined with each other.It below will knot Embodiment is closed the application is described in detail.
Embodiment 1
15 parts of indigo naturalis, 5 parts of borneol, 5 parts of talcum, 2 parts of the root of Dahurain angelica, 10 parts of radix scutellariae, 10 parts of Asian puccoon, 5 parts of gypsum, honeysuckle 6 Part, 5 parts of Radix Notoginseng, 15 parts of Radix Angelicae Sinensis.
Embodiment 2
30 parts of indigo naturalis, 10 parts of ice, 10 parts of talcum, 10 parts of the root of Dahurain angelica, 20 parts of radix scutellariae, 20 parts of Asian puccoon, 10 parts of gypsum, honeysuckle 15 parts, 10 parts of Radix Notoginseng, 30 parts of Radix Angelicae Sinensis.
Embodiment 3
16 parts of indigo naturalis, 6 parts of borneol, 6 parts of talcum, 3 parts of the root of Dahurain angelica, 11 parts of radix scutellariae, 11 parts of Asian puccoon, 6 parts of gypsum, honeysuckle 7 Part, 6 parts of Radix Notoginseng, 16 parts of Radix Angelicae Sinensis.
Embodiment 4
29 parts of indigo naturalis, 9 parts of borneol, 9 parts of talcum, 9 parts of the root of Dahurain angelica, 19 parts of radix scutellariae, 19 parts of Asian puccoon, 9 parts of gypsum, honeysuckle 14 Part, 9 parts of Radix Notoginseng, 29 parts of Radix Angelicae Sinensis.
Embodiment 5
14.5 parts of indigo naturalis, 4.5 parts of borneol, 5.5 parts of talcum, 2.5 parts of the root of Dahurain angelica, 10.5 parts of radix scutellariae, 10.5 parts of Asian puccoon, gypsum 5.5 parts, 6.5 parts of honeysuckle, 5.5 parts of Radix Notoginseng, 15.5 parts of Radix Angelicae Sinensis.
Embodiment 6
30.5 parts of indigo naturalis, 10.5 parts of borneol, 10.5 parts of talcum, 9.5 parts of the root of Dahurain angelica, 19.5 parts of radix scutellariae, 19.5 parts of Asian puccoon, raw stone 9.5 parts of cream, 14.5 parts of honeysuckle, 9.5 parts of Radix Notoginseng, 29.5 parts of Radix Angelicae Sinensis.
Cream base body in the present invention is medical ventolin, it is, of course, also possible to be other cream base bodies, such as solid paraffin, The black powder for erasing is made according to following techniques in any of the above-described embodiment in the present invention by atoleine, beeswax and spermaceti etc. Cream：
(1), the weighing of drug and the mixing of drug；Above-mentioned six kinds of drugs are weighed, and six kinds of drugs are mixed, are mixed thoroughly, shape At hybrid medicine；
(2), the mixing of cream base body；Medical ventolin is taken to be packed into the sterile rustless cylinder sterilized, heating is fused into water The temperature of shape, heating is 20 DEG C -30 DEG C, and the hybrid medicine mixed in (1) is put into cylinder and is stirred evenly with medical ventolin；
(3), it concentrates, at cream；After drug to be mixed is merged with medical ventolin, then black powder paste is formed, aseptic injection is used Device extracts prepared black powder paste in cylinder out, is packed into the aseptic bottle disinfected；
(4), it packs；Aseptic bottle is covered tightly and is obturaged, it is spare to be stored in 10 DEG C of -20 DEG C of shady places above freezing.
Black ointment made of the embodiment of the present invention 1 to embodiment 6 for erasing, is denoted as 1 black ointment of embodiment, reality respectively 6 black ointment of cream, 5 black ointment of embodiment and embodiment in 2 black ointment of example, 3 black ointment of embodiment, 4 medicine of embodiment is applied, after tested, It is relatively as follows compared with control sample 1：
Experiment one：Treatment for psoriatic
Curative effect situation criterion：(1) effective：Color spot pigment is eliminated without precipitation, eczema chronic eczema, and the colour of skin is uniform, scar acne It is effective that print eliminates (2)：Color spot pigment is eliminated without precipitation, eczema chronic eczema, and the colour of skin is substantially uniform, and scar acne print substantially eliminates (3) nothing Effect：Eczema chronic eczema is not eliminated, and the colour of skin is uneven, and scar acne print is not eliminated substantially
Patient's selects：Select 100 psoriatics, average age 30 years old.100 psoriatics are randomly divided into 5 groups, every group of 20 people, every group of correspondence rubs control sample 1 and erasing 1 ointment of embodiment to 6 ointment of embodiment respectively.
Symptom before patient's treatment：100 psoriatics.
Rub dosage：It will first be sterilized at sufferer with thimerosal, then cleaned with physiological saline, be then applied to ointment again Affected part, 1-3 times on the one, one week as a treatment course, and three courses for the treatment of are used continuously.
Interpretation of result：When treating psoriatic, patient rubs control sample efficiently individual quantity and only has 4, and effective percentage is 20%；And the average effectiveness level that patient rubs 1 ointment of embodiment in the present invention to 6 ointment of embodiment is 86.7%, wherein in fact 4 black ointment effective percentage of example is applied up to 95%, it is seen then that 1 ointment of embodiment to 6 ointment of embodiment in the present invention has psoriasis Preferable therapeutic effect, in terms of existing technologies, cure rate higher, curative effect are more preferable.
Present invention also provides the psoriasic black powder ointment preparations for the treatment of, including：
Step 1 weighs the root of Dahurain angelica, radix scutellariae, Asian puccoon, honeysuckle four traditional Chinese medicine material low temperature drying；
Step 2 stirs the medicinal material after indigo naturalis, borneol, Radix Notoginseng, Radix Angelicae Sinensis residue four traditional Chinese medicine and a kind of drying of step equal Even acquisition micropowders；
Step 3 does excipient with vaseline；
The medicinal powder of corresponding proportion is added in step 4；
Step 5 is stirred continuously, and medicinal powder is made to be merged with vaseline uniformly.
Low temperature drying is used as the preferred of above-mentioned preparation method, in the step 16 hours, wherein cryogenic temperature control System is at 35 DEG C -45 DEG C.
As the preferred of above-mentioned preparation method, the step 4 Chinese medicine accounting is between 15%-40%.
As the preferred of above-mentioned preparation method, the step 5 specifically includes：Corresponding vaseline is weighed, stainless steel appearance is set In device；Heating makes vaseline melt, until vaseline is clear transparent.
It is a small amount of, multiple that medicinal powder is added as the preferred of above-mentioned preparation method, in the step 4, prevents that excessive appearance is added Caking phenomenon.
As the preferred of above-mentioned preparation method, further include：Step 6 prepares dress canister, packing ointment, waits for that ointment cooling is solidifying Sealing fills.
By treating the ingredient that psoriasic black ointment includes following mass fraction made from above-mentioned preparation method：Indigo naturalis 15-30 parts, 5-10 parts of borneol, 5-10 parts of talcum, 2-10 parts of the root of Dahurain angelica, 10-20 parts of radix scutellariae, 10-20 parts of Asian puccoon, gypsum 5-10 Part, 6-15 parts of honeysuckle, 5-10 parts of Radix Notoginseng, 15-30 parts of Radix Angelicae Sinensis.
Black ointment in the application also contains other than clearing heat and detoxicating effect and grows Run skins Skin, function promoting blood circulation and removing blood stasis, therefore Other than it can solve the psoriasic dry symptom for itching furfur, moreover it is possible to raw new effect of going to become silted up is generated to skin, it is advantageous that sharp With the drug for invigorating blood circulation and eliminating stasis in Chinese medicine, the plasma metabolism speed in subcutaneous capilary is promoted to increase, and then improve color spot, pigment is heavy It forms sediment, the problem of colour of skin unevenness.
The preferred embodiment that these are only the application, is not intended to limit this application, for those skilled in the art For member, the application can have various modifications and variations.Any modification made by within the spirit and principles of this application, Equivalent replacement, improvement etc., should be included within the protection domain of the application.

Claims (10)

1. a kind for the treatment of psoriasic black ointment, which is characterized in that include the ingredient of following mass fraction：15-30 parts of indigo naturalis, ice 5-10 parts of piece, 5-10 parts of talcum, 2-10 parts of the root of Dahurain angelica, 10-20 parts of radix scutellariae, 10-20 parts of Asian puccoon, 5-10 parts of gypsum, honeysuckle 6- 15 parts, 5-10 parts of Radix Notoginseng, 15-30 parts of Radix Angelicae Sinensis.
2. black ointment according to claim 1, which is characterized in that include the ingredient of following mass fraction：Indigo naturalis 16-29 Part, 6-9 parts of borneol, 6-9 parts of talcum, 3-9 parts of the root of Dahurain angelica, 11-19 parts of radix scutellariae, 11-19 parts of Asian puccoon, 6-9 parts of gypsum, honeysuckle 7- 14 parts, 6-9 parts of Radix Notoginseng, 16-29 parts of Radix Angelicae Sinensis.
3. black ointment according to claim 1, which is characterized in that include the ingredient of following mass fraction：Indigo naturalis 14.5- 30.5 parts, 4.5-10.5 parts of borneol, 5.5-10.5 parts of talcum, 2.5-9.5 parts of the root of Dahurain angelica, 10.5-19.5 parts of radix scutellariae, Asian puccoon 10.5- 19.5 parts, 5.5-9.5 parts of gypsum, 6.5-14.5 parts of honeysuckle, 5.5-9.5 parts of Radix Notoginseng, 15.5-29.5 parts of Radix Angelicae Sinensis.
4. the black ointment described in a kind of any one of claims 1 to 3 claim is preparing treatment psoriasis in middle treatment Application in drug.
5. a kind for the treatment of psoriasic black powder ointment preparation, which is characterized in that including：
Step 1 weighs the root of Dahurain angelica, radix scutellariae, Asian puccoon, honeysuckle four traditional Chinese medicine material low temperature drying；
Medicinal material after indigo naturalis, borneol, Radix Notoginseng, Radix Angelicae Sinensis residue four traditional Chinese medicine and a kind of drying of step is stirred evenly and is obtained by step 2 Obtain micropowders；
Step 3 does excipient with vaseline；
The medicinal powder of corresponding proportion is added in step 4；
Step 5 is stirred continuously, and medicinal powder is made to be merged with vaseline uniformly.
6. black powder ointment preparation according to claim 5, which is characterized in that use low temperature drying 6 in the step 1 Hour, wherein cryogenic temperature is controlled at 35 DEG C -45 DEG C.
7. black powder ointment preparation according to claim 5, which is characterized in that the step 4 Chinese medicine accounting is 15%- Between 40%.
8. black powder ointment preparation according to claim 5, which is characterized in that the step 5 specifically includes：Weigh phase The vaseline answered, sets in rustless steel container；Heating makes vaseline melt, until vaseline is clear transparent.
9. black powder ointment preparation according to claim 5, which is characterized in that be added in the step 4 medicinal powder it is a small amount of, Repeatedly, it prevents from being added and excessively caking phenomenon occurs.
10. black powder ointment preparation according to claim 5, which is characterized in that further include：Step 6, preparation dress canister, Ointment is dispensed, waits for that ointment cooled and solidified encapsulates.
CN201810983304.2A 2018-08-27 2018-08-27 Treat psoriasic black ointment itself and preparation method Pending CN108743673A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111803582A (en) * 2020-08-06 2020-10-23 辽宁宝一堂科技发展有限公司 Preparation method of traditional Chinese medicine packet for treating psoriasis

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104800269A (en) * 2015-05-19 2015-07-29 北京市中医研究所 Traditional Chinese medicine external-use cream used for treating psoriasis and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104800269A (en) * 2015-05-19 2015-07-29 北京市中医研究所 Traditional Chinese medicine external-use cream used for treating psoriasis and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111803582A (en) * 2020-08-06 2020-10-23 辽宁宝一堂科技发展有限公司 Preparation method of traditional Chinese medicine packet for treating psoriasis

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