CN111803582A - Preparation method of traditional Chinese medicine packet for treating psoriasis - Google Patents

Preparation method of traditional Chinese medicine packet for treating psoriasis Download PDF

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Publication number
CN111803582A
CN111803582A CN202010781100.8A CN202010781100A CN111803582A CN 111803582 A CN111803582 A CN 111803582A CN 202010781100 A CN202010781100 A CN 202010781100A CN 111803582 A CN111803582 A CN 111803582A
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parts
reaction kettle
medicine
traditional chinese
water
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伊彩虹
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Liaoning Baoyitang Science And Technology Development Co ltd
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Liaoning Baoyitang Science And Technology Development Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/28Mercury; Compounds thereof
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    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/58Reptiles
    • A61K35/583Snakes; Lizards, e.g. chameleons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482Cassia, e.g. golden shower tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/483Gleditsia (locust)
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/884Alismataceae (Water-plantain family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966Fritillaria, e.g. checker lily or mission bells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics

Abstract

The invention discloses a preparation method of a traditional Chinese medicine packet for treating psoriasis, which comprises the following steps: s1: preparing the following raw materials in parts by weight: 8-15 parts of pangolin scales, 10-20 parts of bulbus fritilariae, 10-20 parts of saponin, 15-25 parts of dried orange peel, 2-8 parts of cassia seed, 3-8 parts of rhubarb, 8-15 parts of cantharis, 10-15 parts of long-noded pit viper, 10-20 parts of rhizoma typhonii, 5-12 parts of rhizoma alismatis, 10-20 parts of pseudo-ginseng, 3-8 parts of hydrargyri oxydum rubrum, 20-30 parts of honeysuckle, 10-20 parts of lithospermum, 8-15 parts of radix isatidis, 4-10 parts of cortex cinnamomi, 10-20 parts of radix angelicae, 10-25 parts of spina gleditsiae and 400 parts of purified water; s2: dividing purified water into a first part of water and a second part of water according to the ratio of 3: 1; a reaction kettle is prepared, and then the argon replacement reaction is carried out on the interior of the reaction kettle. The traditional Chinese medicine package is reasonable in design, and the traditional Chinese medicine package prepared by taking various traditional Chinese medicinal materials as raw materials can achieve an obvious treatment effect on psoriasis symptoms, so that the actual requirements of users can be met.

Description

Preparation method of traditional Chinese medicine packet for treating psoriasis
Technical Field
The invention relates to the technical field of traditional Chinese pharmacology, in particular to a preparation method of a traditional Chinese medicine packet for treating psoriasis.
Background
Psoriasis is a common chronic easily-relapsed inflammatory skin disease with characteristic skin lesions, the number of patients with psoriasis symptoms is large in China, and the psychology of the patients is greatly stressed due to the obvious expression characteristics of the psoriasis; with the continuous improvement of the pursuit of health problems and beauty of people at present, how to realize the treatment of psoriasis symptoms is urgently needed to be solved, and therefore, a preparation method of a traditional Chinese medicine packet for treating psoriasis is designed to solve the problems.
Disclosure of Invention
The invention aims to solve the problem that the existing psoriasis symptom is difficult to treat, and provides a preparation method of a traditional Chinese medicine packet for treating psoriasis.
In order to achieve the purpose, the invention adopts the following technical scheme:
a preparation method of a traditional Chinese medicine packet for treating psoriasis comprises the following steps:
s1: preparing the following raw materials in parts by weight: 8-15 parts of pangolin scales, 10-20 parts of bulbus fritilariae, 10-20 parts of saponin, 15-25 parts of dried orange peel, 2-8 parts of cassia seed, 3-8 parts of rhubarb, 8-15 parts of cantharis, 10-15 parts of long-noded pit viper, 10-20 parts of rhizoma typhonii, 5-12 parts of rhizoma alismatis, 10-20 parts of pseudo-ginseng, 3-8 parts of hydrargyri oxydum rubrum, 20-30 parts of honeysuckle, 10-20 parts of lithospermum, 8-15 parts of radix isatidis, 4-10 parts of cortex cinnamomi, 10-20 parts of radix angelicae, 10-25 parts of spina gleditsiae and 400 parts of purified water;
s2: dividing purified water into a first part of water and a second part of water according to the ratio of 3: 1; preparing a reaction kettle, carrying out argon displacement reaction on the interior of the reaction kettle to clean the interior of the reaction kettle, sequentially putting bulbus fritilariae, saponin, semen cassiae, rheum officinale, rhizoma typhonii, rhizoma alismatis, pseudo-ginseng, honeysuckle, lithospermum, radix isatidis, cortex cinnamomi, radix angelicae, spina gleditsiae and a first part of water into the reaction kettle, raising the temperature of the reaction kettle to 140 ℃ plus materials, heating for 15-25min, adjusting the temperature of the reaction kettle to 60-70 ℃, heating for 2-4h, and after heating is finished, carrying out liquid medicine separation on the interior of the reaction kettle through filter cloth to obtain a first part of liquid medicine and a first part of dregs of a decoction;
s3: putting the first part of the medicine residues into the reaction kettle again, putting the second part of water into the reaction kettle, adjusting the temperature of the reaction kettle to 50-70 ℃, heating for 2-3 hours, and then carrying out medicine liquid separation work on the interior of the reaction kettle through filter cloth to obtain a second part of medicine liquid and second part of medicine residues;
s4: stirring and mixing the first part of liquid medicine and the second part of liquid medicine through a stirring rod to obtain mixed liquid medicine, putting the mixed liquid medicine into a freeze dryer for freeze drying to obtain a freeze-dried substance, and grinding the freeze-dried substance to obtain a first powdery medicine;
s5: sequentially grinding squama Manis, pericarpium Citri Tangerinae, Mylabris and Agkistrodon into powder, and mixing and stirring the grinded squama Manis, pericarpium Citri Tangerinae, Mylabris and Agkistrodon to obtain a second powder medicine;
s6: sequentially putting the first powdery medicine and the second powdery medicine into a mixer, starting the mixer to perform mixing operation, wherein the rotating speed of the mixer is 200-;
s7: and filling the mixed medicines into a packaging bag to obtain the traditional Chinese medicine packaging bag for treating psoriasis.
Preferably, in S2, the number of times of the argon replacement reaction is performed is 3 to 6 times.
Compared with the prior art, the invention has the beneficial effects that:
squama Manis for treating carbuncle, cellulitis, sore, and swelling; bulbus Fritillariae Cirrhosae is used for treating swelling and sore throat; fructus Gleditsiae Abnormalis has effects of relieving swelling, removing toxic substance, expelling pus, and killing parasite; pericarpium Citri Tangerinae has effects of regulating qi-flowing, invigorating spleen, eliminating dampness and eliminating phlegm; semen Cassiae has analgesic effect; radix Rumicis has effects of clearing away heat and toxic materials, cooling blood, stopping bleeding, removing blood stasis, and relieving swelling; mylabris has effects of removing blood stasis, resolving hard mass, eliminating cripple, removing toxic materials, and eliminating sore; the Agkistrodon has effects of dispelling pathogenic wind and removing dampness, penetrating tendons and bones, and arresting convulsion; rhizoma Typhonii has effects of dispelling pathogenic wind phlegm, arresting convulsion, removing toxic substance, resolving hard mass, and relieving pain; rhizoma Alismatis has repercussive and suppurative effects; notoginseng radix has hemostatic, blood stasis dispelling, antiinflammatory, analgesic, and tonic effects; the red powder has antibacterial effect; the honeysuckle has the effects of clearing away heat and toxic materials; radix Arnebiae has anti-tumor, antiinflammatory, pathogenic microorganism resisting, analgesic, and tranquilizing effects; radix Isatidis has effects of clearing away heat and toxic materials, and cooling blood; cortex Cinnamomi has effects of lowering blood pressure and relieving pain; radix Angelicae Dahuricae has effects of dispelling pathogenic wind, eliminating dampness, relieving swelling and pain; spina Gleditsiae has effects in relieving swelling, expelling toxic materials, promoting pus discharge, and killing parasite;
in conclusion, the traditional Chinese medicine package is reasonable in design, and the traditional Chinese medicine package prepared by taking various traditional Chinese medicinal materials as raw materials can achieve an obvious treatment effect on psoriasis symptoms, so that the actual requirements of users can be met.
Detailed Description
The following will clearly and completely describe the technical solutions in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments.
Example 1
A preparation method of a traditional Chinese medicine packet for treating psoriasis comprises the following steps:
s1: preparing the following raw materials in parts by weight: 8 parts of pangolin scales, 10 parts of bulbus fritilariae, 10 parts of saponin, 15 parts of dried orange peel, 2 parts of semen cassiae, 3 parts of rumex madaio, 8 parts of cantharis, 10 parts of long-noded pit viper, 10 parts of rhizoma typhonii, 5 parts of rhizoma alismatis, 10 parts of pseudo-ginseng, 3 parts of red powder, 20 parts of honeysuckle, 10 parts of lithospermum, 8 parts of radix isatidis, 4 parts of cortex cinnamomi, 10 parts of radix angelicae, 10 parts of spina gleditsiae and 300 parts of purified water;
s2: dividing purified water into a first part of water and a second part of water according to the ratio of 3: 1; preparing a reaction kettle, carrying out argon displacement reaction work on the interior of the reaction kettle, wherein the number of the argon displacement reaction work is 3, cleaning the interior of the reaction kettle, sequentially putting bulbus fritilariae, saponin, semen cassiae, rheum officinale, rhizoma typhonii, rhizoma alismatis, pseudo-ginseng, honeysuckle, lithospermum, radix isatidis, cortex cinnamomi, radix angelicae, spina gleditsiae and a first part of water into the reaction kettle, raising the temperature of the reaction kettle to 120 ℃, heating for 15min, adjusting the temperature of the reaction kettle to 60 ℃, heating for 2h, and after heating, carrying out liquid medicine separation work on the interior of the reaction kettle through filter cloth to obtain a first part of liquid medicine and a first part of dregs of decoction;
s3: putting the first part of the medicine residues into the reaction kettle again, putting the second part of water into the reaction kettle, adjusting the temperature of the reaction kettle to 50 ℃, heating for 2 hours, and then carrying out medicine liquid separation work on the interior of the reaction kettle through filter cloth to obtain a second part of medicine liquid and second part of medicine residues;
s4: stirring and mixing the first part of liquid medicine and the second part of liquid medicine through a stirring rod to obtain mixed liquid medicine, putting the mixed liquid medicine into a freeze dryer for freeze drying to obtain a freeze-dried substance, and grinding the freeze-dried substance to obtain a first powdery medicine;
s5: sequentially grinding squama Manis, pericarpium Citri Tangerinae, Mylabris and Agkistrodon into powder, and mixing and stirring the grinded squama Manis, pericarpium Citri Tangerinae, Mylabris and Agkistrodon to obtain a second powder medicine;
s6: sequentially putting the first powdery medicine and the second powdery medicine into a mixer, starting the mixer to perform mixing operation, wherein the rotating speed of the mixer is 200 revolutions per minute, and the rotating time is 5 minutes, so as to obtain mixed medicines;
s7: and filling the mixed medicines into a packaging bag to obtain the traditional Chinese medicine packaging bag for treating psoriasis.
Example 2
A preparation method of a traditional Chinese medicine packet for treating psoriasis comprises the following steps:
s1: preparing the following raw materials in parts by weight: 10 parts of pangolin scales, 12 parts of bulbus fritillariae cirrhosae, 12 parts of saponin, 18 parts of dried orange peel, 4 parts of semen cassiae, 5 parts of rumex madaio, 10 parts of cantharis, 12 parts of long-noded pit viper, 12 parts of rhizoma typhonii, 7 parts of rhizoma alismatis, 12 parts of pseudo-ginseng, 5 parts of red powder, 22 parts of honeysuckle, 12 parts of lithospermum, 10 parts of radix isatidis, 6 parts of cortex cinnamomi, 12 parts of radix angelicae, 12 parts of spina gleditsiae and 340 parts of purified water;
s2: dividing purified water into a first part of water and a second part of water according to the ratio of 3: 1; preparing a reaction kettle, carrying out argon displacement reaction work on the interior of the reaction kettle, wherein the number of the argon displacement reaction work is 4, cleaning the interior of the reaction kettle, sequentially putting bulbus fritilariae, saponin, semen cassiae, rheum officinale, rhizoma typhonii, rhizoma alismatis, pseudo-ginseng, honeysuckle, lithospermum, radix isatidis, cortex cinnamomi, radix angelicae, spina gleditsiae and a first part of water into the reaction kettle, raising the temperature of the reaction kettle to 125 ℃, heating for 18min, adjusting the temperature of the reaction kettle to 65 ℃, heating for 2.2h, and after heating, carrying out liquid medicine separation work on the interior of the reaction kettle through filter cloth to obtain a first part of liquid medicine and a first part of dregs of a decoction;
s3: putting the first part of the medicine residues into the reaction kettle again, putting the second part of water into the reaction kettle, adjusting the temperature of the reaction kettle to 55 ℃, heating for 2.4 hours, and then carrying out medicine liquid separation work on the interior of the reaction kettle through filter cloth to obtain a second part of medicine liquid and second part of medicine residues;
s4: stirring and mixing the first part of liquid medicine and the second part of liquid medicine through a stirring rod to obtain mixed liquid medicine, putting the mixed liquid medicine into a freeze dryer for freeze drying to obtain a freeze-dried substance, and grinding the freeze-dried substance to obtain a first powdery medicine;
s5: sequentially grinding squama Manis, pericarpium Citri Tangerinae, Mylabris and Agkistrodon into powder, and mixing and stirring the grinded squama Manis, pericarpium Citri Tangerinae, Mylabris and Agkistrodon to obtain a second powder medicine;
s6: sequentially putting the first powdery medicine and the second powdery medicine into a mixer, starting the mixer to perform mixing operation, wherein the rotating speed of the mixer is 240 revolutions per minute, and the rotating time is 7 minutes to obtain mixed medicines;
s7: and filling the mixed medicines into a packaging bag to obtain the traditional Chinese medicine packaging bag for treating psoriasis.
Example 3
A preparation method of a traditional Chinese medicine packet for treating psoriasis comprises the following steps:
s1: preparing the following raw materials in parts by weight: 12 parts of pangolin scales, 18 parts of bulbus fritilariae, 18 parts of saponin, 22 parts of dried orange peel, 6 parts of semen cassiae, 6 parts of rumex madaio, 12 parts of cantharis, 14 parts of long-noded pit viper, 18 parts of rhizoma typhonii, 10 parts of rhizoma alismatis, 18 parts of pseudo-ginseng, 6 parts of red powder, 28 parts of honeysuckle, 18 parts of lithospermum, 13 parts of radix isatidis, 8 parts of cortex cinnamomi, 18 parts of radix angelicae, 22 parts of spina gleditsiae and 380 parts of purified water;
s2: dividing purified water into a first part of water and a second part of water according to the ratio of 3: 1; preparing a reaction kettle, carrying out argon displacement reaction work on the interior of the reaction kettle, wherein the number of the argon displacement reaction work is 5, cleaning the interior of the reaction kettle, sequentially putting bulbus fritilariae, saponin, semen cassiae, rheum officinale, rhizoma typhonii, rhizoma alismatis, pseudo-ginseng, honeysuckle, lithospermum, radix isatidis, cortex cinnamomi, radix angelicae, spina gleditsiae and a first part of water into the reaction kettle, raising the temperature of the reaction kettle to 130 ℃, heating for 22min, adjusting the temperature of the reaction kettle to 68 ℃, heating for 3.5h, and after heating, carrying out liquid medicine separation work on the interior of the reaction kettle through filter cloth to obtain a first part of liquid medicine and a first part of dregs of a decoction;
s3: putting the first part of the medicine residues into the reaction kettle again, putting the second part of water into the reaction kettle, adjusting the temperature of the reaction kettle to 65 ℃, heating for 2.8 hours, and then carrying out medicine liquid separation work on the interior of the reaction kettle through filter cloth to obtain a second part of medicine liquid and second part of medicine residues;
s4: stirring and mixing the first part of liquid medicine and the second part of liquid medicine through a stirring rod to obtain mixed liquid medicine, putting the mixed liquid medicine into a freeze dryer for freeze drying to obtain a freeze-dried substance, and grinding the freeze-dried substance to obtain a first powdery medicine;
s5: sequentially grinding squama Manis, pericarpium Citri Tangerinae, Mylabris and Agkistrodon into powder, and mixing and stirring the grinded squama Manis, pericarpium Citri Tangerinae, Mylabris and Agkistrodon to obtain a second powder medicine;
s6: sequentially putting the first powdery medicine and the second powdery medicine into a mixer, starting the mixer to mix, wherein the rotating speed of the mixer is 280 revolutions per minute, and the rotating time is 8 minutes, so as to obtain mixed medicines;
s7: and filling the mixed medicines into a packaging bag to obtain the traditional Chinese medicine packaging bag for treating psoriasis.
Example 4
A preparation method of a traditional Chinese medicine packet for treating psoriasis comprises the following steps:
s1: preparing the following raw materials in parts by weight: 15 parts of pangolin scales, 20 parts of bulbus fritilariae, 20 parts of saponin, 25 parts of dried orange peel, 8 parts of semen cassiae, 8 parts of rumex madaio, 15 parts of cantharis, 15 parts of long-noded pit viper, 20 parts of rhizoma typhonii, 12 parts of rhizoma alismatis, 20 parts of pseudo-ginseng, 8 parts of red powder, 30 parts of honeysuckle, 20 parts of lithospermum, 15 parts of radix isatidis, 10 parts of cortex cinnamomi, 20 parts of radix angelicae, 25 parts of spina gleditsiae and 400 parts of purified water;
s2: dividing purified water into a first part of water and a second part of water according to the ratio of 3: 1; preparing a reaction kettle, carrying out argon displacement reaction work on the interior of the reaction kettle, wherein the number of the argon displacement reaction work is 6, cleaning the interior of the reaction kettle, sequentially putting bulbus fritilariae, saponin, semen cassiae, rheum officinale, rhizoma typhonii, rhizoma alismatis, pseudo-ginseng, honeysuckle, lithospermum, radix isatidis, cortex cinnamomi, radix angelicae, spina gleditsiae and a first part of water into the reaction kettle, raising the temperature of the reaction kettle to 140 ℃, heating for 25min, adjusting the temperature of the reaction kettle to 70 ℃, heating for 4h, and after heating, carrying out liquid medicine separation work on the interior of the reaction kettle through filter cloth to obtain a first part of liquid medicine and a first part of dregs of decoction;
s3: putting the first part of the medicine residues into the reaction kettle again, putting the second part of water into the reaction kettle, adjusting the temperature of the reaction kettle to 70 ℃, heating for 3 hours, and then carrying out medicine liquid separation work on the interior of the reaction kettle through filter cloth to obtain a second part of medicine liquid and second part of medicine residues;
s4: stirring and mixing the first part of liquid medicine and the second part of liquid medicine through a stirring rod to obtain mixed liquid medicine, putting the mixed liquid medicine into a freeze dryer for freeze drying to obtain a freeze-dried substance, and grinding the freeze-dried substance to obtain a first powdery medicine;
s5: sequentially grinding squama Manis, pericarpium Citri Tangerinae, Mylabris and Agkistrodon into powder, and mixing and stirring the grinded squama Manis, pericarpium Citri Tangerinae, Mylabris and Agkistrodon to obtain a second powder medicine;
s6: sequentially putting the first powdery medicine and the second powdery medicine into a mixer, starting the mixer to perform mixing operation, wherein the rotating speed of the mixer is 300 revolutions per minute, and the rotating time is 10 minutes, so as to obtain mixed medicines;
s7: and filling the mixed medicines into a packaging bag to obtain the traditional Chinese medicine packaging bag for treating psoriasis.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.

Claims (2)

1. A preparation method of a traditional Chinese medicine packet for treating psoriasis is characterized by comprising the following steps:
s1: preparing the following raw materials in parts by weight: 8-15 parts of pangolin scales, 10-20 parts of bulbus fritilariae, 10-20 parts of saponin, 15-25 parts of dried orange peel, 2-8 parts of cassia seed, 3-8 parts of rhubarb, 8-15 parts of cantharis, 10-15 parts of long-noded pit viper, 10-20 parts of rhizoma typhonii, 5-12 parts of rhizoma alismatis, 10-20 parts of pseudo-ginseng, 3-8 parts of hydrargyri oxydum rubrum, 20-30 parts of honeysuckle, 10-20 parts of lithospermum, 8-15 parts of radix isatidis, 4-10 parts of cortex cinnamomi, 10-20 parts of radix angelicae, 10-25 parts of spina gleditsiae and 400 parts of purified water;
s2: dividing purified water into a first part of water and a second part of water according to the ratio of 3: 1; preparing a reaction kettle, carrying out argon displacement reaction on the interior of the reaction kettle to clean the interior of the reaction kettle, sequentially putting bulbus fritilariae, saponin, semen cassiae, rheum officinale, rhizoma typhonii, rhizoma alismatis, pseudo-ginseng, honeysuckle, lithospermum, radix isatidis, cortex cinnamomi, radix angelicae, spina gleditsiae and a first part of water into the reaction kettle, raising the temperature of the reaction kettle to 140 ℃ plus materials, heating for 15-25min, adjusting the temperature of the reaction kettle to 60-70 ℃, heating for 2-4h, and after heating is finished, carrying out liquid medicine separation on the interior of the reaction kettle through filter cloth to obtain a first part of liquid medicine and a first part of dregs of a decoction;
s3: putting the first part of the medicine residues into the reaction kettle again, putting the second part of water into the reaction kettle, adjusting the temperature of the reaction kettle to 50-70 ℃, heating for 2-3 hours, and then carrying out medicine liquid separation work on the interior of the reaction kettle through filter cloth to obtain a second part of medicine liquid and second part of medicine residues;
s4: stirring and mixing the first part of liquid medicine and the second part of liquid medicine through a stirring rod to obtain mixed liquid medicine, putting the mixed liquid medicine into a freeze dryer for freeze drying to obtain a freeze-dried substance, and grinding the freeze-dried substance to obtain a first powdery medicine;
s5: sequentially grinding squama Manis, pericarpium Citri Tangerinae, Mylabris and Agkistrodon into powder, and mixing and stirring the grinded squama Manis, pericarpium Citri Tangerinae, Mylabris and Agkistrodon to obtain a second powder medicine;
s6: sequentially putting the first powdery medicine and the second powdery medicine into a mixer, starting the mixer to perform mixing operation, wherein the rotating speed of the mixer is 200-;
s7: and filling the mixed medicines into a packaging bag to obtain the traditional Chinese medicine packaging bag for treating psoriasis.
2. The method as claimed in claim 1, wherein the number of argon substitution reaction processes in S2 is 3-6.
CN202010781100.8A 2020-08-06 2020-08-06 Preparation method of traditional Chinese medicine packet for treating psoriasis Pending CN111803582A (en)

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Publication number Priority date Publication date Assignee Title
CN102335265A (en) * 2011-10-08 2012-02-01 太原海成生物医药科技有限公司 Chinese medicament for treating psoriasis
CN108743673A (en) * 2018-08-27 2018-11-06 谢允超 Treat psoriasic black ointment itself and preparation method
CN111281948A (en) * 2020-04-22 2020-06-16 辽宁宝一堂科技发展有限公司 Preparation method of Baicao antibacterial cream

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