CN111939227A - Ginseng and astragalus purple white tissue regeneration promoting paste for treating pressure injury and preparation method thereof - Google Patents

Ginseng and astragalus purple white tissue regeneration promoting paste for treating pressure injury and preparation method thereof Download PDF

Info

Publication number
CN111939227A
CN111939227A CN202010867891.6A CN202010867891A CN111939227A CN 111939227 A CN111939227 A CN 111939227A CN 202010867891 A CN202010867891 A CN 202010867891A CN 111939227 A CN111939227 A CN 111939227A
Authority
CN
China
Prior art keywords
parts
paste
roller
decoction
astragalus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202010867891.6A
Other languages
Chinese (zh)
Inventor
李兴云
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xing'an Jieshou Orthopedic Hospital Co ltd
Original Assignee
Xing'an Jieshou Orthopedic Hospital Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xing'an Jieshou Orthopedic Hospital Co ltd filed Critical Xing'an Jieshou Orthopedic Hospital Co ltd
Priority to CN202010867891.6A priority Critical patent/CN111939227A/en
Publication of CN111939227A publication Critical patent/CN111939227A/en
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/739Sanguisorba (burnet)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

The invention discloses a ginseng and astragalus purple white tissue regeneration promoting paste for treating pressure injury and a preparation method thereof, belonging to the technical field of medicaments, and the tissue regeneration promoting paste comprises the following raw materials in parts by weight: 6-10 parts of astragalus; 2-5 parts of angelica; 2-5 parts of radix angelicae; 0.5-2 parts of garden burnet; 0.5-2 parts of bletilla striata; 3-7 parts of radix rehmanniae; 2-5 parts of lithospermum; 0.5-2 parts of paris; 0.5-2 parts of borneol; 36-70 parts of auxiliary materials, and the preparation method comprises the following steps: weighing the raw materials; grinding the weighed borneol into powder, and sieving to obtain borneol fine powder; decocting the rest materials except Borneolum Syntheticum and adjuvants in water for 2 times; then filtering, and merging the decoction to obtain filtrate; concentrating the filtrate at 80 deg.C, adding adjuvants, sterilizing, adding the above Borneolum fine powder when the temperature is reduced to below 60 deg.C, mixing, stirring, and standing to obtain SHENQIZIBAISHENG ointment.

Description

Ginseng and astragalus purple white tissue regeneration promoting paste for treating pressure injury and preparation method thereof
Technical Field
The invention relates to the technical field of medicines, in particular to ginseng and astragalus purple-white tissue regeneration promoting paste for treating pressure injury and a preparation method thereof.
Background
The application of the traditional Chinese medicine tissue regeneration promoting ointment to the treatment of pressure injury is reported, and partial scholars think that the detoxifying tissue regeneration promoting ointment belongs to an oil ointment and can be uniformly distributed on a wound surface, so that the liquefaction of necrotic tissues is accelerated to facilitate drainage; some researchers believe that the ointment for removing the necrotic tissue and promoting tissue regeneration is locally applied to treat diabetes mellitus complicated by pressure injury, is beneficial to medicine absorption, plays the functions of diminishing inflammation, resisting bacteria, promoting blood circulation and removing blood stasis, conforms to the theory of moist healing, and can accelerate the healing of the pressure injury. However, no report about a wound debridement method of the granulation promoting ointment is found, debridement is an important link of pressure injury treatment, and the combined debridement effect is considered to be obvious in many reports. Research shows that the combined debridement can achieve the purposes of treatment, dissolution and removal at the same time, accelerate the debridement process, shorten the debridement period and promote the early healing of the wound surface. In the combined debridement, debridement glue of different brands is used for autolysis debridement, and debridement of chronic wounds by an external treatment method of traditional Chinese medicine is also reported.
With the increase of cerebral apoplexy and severe multiple fracture cases, the incidence rate of the pressure injury is increased. Most of the traditional Chinese medicines can promote blood circulation and promote tissue regeneration, astringe and remove slough, the principle is similar to autolytic debridement, the traditional Chinese medicines have various dosage forms, the traditional Chinese medicines are mostly self-made by various institutions, generally, medical care medicines are in application ranges of exploring different debridement techniques, and the trend of developing chronic wounds is to find safe, economic and obvious debridement methods.
In view of the above, the invention provides a ginseng and astragalus purple white tissue regeneration promoting paste for treating pressure injury and a preparation method thereof.
Disclosure of Invention
Aiming at the defects in the prior art, the invention aims to provide the ginseng-astragalus-purple white tissue regeneration promoting paste for treating pressure injury and the preparation method thereof.
In order to achieve the purpose, the invention provides the following technical scheme:
the ginseng-astragalus-purple white tissue regeneration promoting paste for treating the pressure injury comprises the following raw materials in parts by weight:
6-10 parts of astragalus;
2-5 parts of angelica;
2-5 parts of radix angelicae;
0.5-2 parts of garden burnet;
0.5-2 parts of bletilla striata;
3-7 parts of radix rehmanniae;
2-5 parts of lithospermum;
0.5-2 parts of paris;
0.5-2 parts of borneol;
36-70 parts of auxiliary materials.
More preferably: the auxiliary materials comprise sesame oil and vaseline, wherein the mass ratio of the sesame oil to the vaseline is 1: (6-8).
More preferably: the feed comprises the following raw materials in parts by weight:
8 parts of astragalus;
4 parts of angelica;
3 parts of radix angelicae;
1 part of garden burnet;
1 part of bletilla striata;
5 parts of radix rehmanniae;
4 parts of lithospermum;
1 part of paris rhizome;
1 part of borneol;
6 parts of sesame oil;
42 parts of auxiliary materials;
a preparation method of a ginseng and astragalus purple white muscle regeneration promoting paste for treating pressure injury comprises the following steps:
s1, weighing
Weighing the raw materials according to the weight parts of the raw materials of the tissue regeneration promoting paste;
s2 grinding Borneolum Syntheticum into powder
Grinding the weighed borneol into powder, and sieving the powder by a sieve of 30-60 meshes to obtain borneol fine powder;
s3 preparation of tissue regeneration promoting ointment
Decocting the rest materials except Borneolum Syntheticum and adjuvants in water for 2 times with a decocting device, wherein each time, the materials are first decocted with strong fire until water is boiling, and then decocted with slow fire for 1-1.5 hr; then filtering, and merging the decoction to obtain filtrate; concentrating the filtrate at 80 deg.C, adding adjuvants, sterilizing, adding the above Borneolum fine powder when the temperature is reduced to below 60 deg.C, mixing, stirring for 25-40min, and standing to obtain SHENQIZIBAOSHENG ointment.
More preferably: the decocting device comprises a tank body, a stirring device and a discharging device, the tank body sequentially comprises a heating cavity, a decoction cavity and a medicinal material cavity from bottom to top, and the discharging device is positioned between the decoction cavity and the medicinal material cavity and is used for intercepting medicinal materials in the medicinal material cavity; the stirring device is used for stirring the medicinal materials and the decoction in the medicinal material cavity; the decoction cavity is provided with a liquid outlet, and the medicinal material cavity is provided with a feed inlet.
During the decoction process, the other raw materials except the borneol and the auxiliary materials are added into the medicinal material cavity, and then water is added to soak the medicinal material in the water.
More preferably: the stirring device comprises a motor, a stirring shaft and blades;
the top of the medicinal material cavity is provided with a cover plate, the motor is installed in the center of the cover plate, the stirring shaft is vertically arranged, the upper end of the stirring shaft penetrates through the cover plate to be connected with the output shaft of the motor, and the lower end of the stirring shaft is close to the center of the bottom of the medicinal material cavity;
the paddle is installed on the stirring shaft and is coaxially and rotatably arranged with the stirring shaft.
More preferably: the blanking device comprises a roller, an annular tooth surface, a worm wheel, a worm, a gear and a connecting shaft;
a feed opening is arranged between the decoction cavity and the medicinal material cavity, the roller is installed in the feed opening, the upper part of the circumferential surface of the roller is positioned in the medicinal material cavity, the lower part of the circumferential surface is positioned in the decoction cavity, the axial direction of the roller is vertical to the axial direction of the stirring shaft, and the roller is rotationally connected to the tank body; the circumferential surface of the roller is provided with a first filtering hole for passing through decoction;
the annular tooth surface is sleeved on the roller and fixedly connected with the circumferential surface of the roller, the worm is fixed at the lower part of the stirring shaft, the worm wheel is positioned at one side of the worm and meshed with the worm, two ends of the connecting shaft are rotatably connected with the side part of the tank body, and the middle part of the connecting shaft penetrates through the center of the worm wheel and is coaxially and rotatably arranged with the worm wheel;
the gear is fixed in the axial direction of the connecting shaft and meshed with the annular tooth surface, so that when the connecting shaft rotates, the roller rotates around the central shaft of the roller at the feed opening.
More preferably: the blanking device further comprises an arc sheet, the arc sheet is located in the decoction cavity and located below and on the side of the circumferential surface of the roller, the inner arc surface of the arc sheet faces the roller, a second filtering hole is formed in the arc sheet, and the aperture of the second filtering hole is smaller than that of the first filtering hole.
More preferably: the connecting rod is fixed on the arc piece, the connecting plate is fixed on the roller and is in bolted connection with the connecting rod, and the connecting plate is rotatably connected on the roller.
More preferably: the cylinder circumference surface has seted up the spout, the spout sets up the form for the ring and is T type spout, the connecting plate with spout looks adaptation, the connecting plate inlay in the spout and with spout sliding fit.
In conclusion, the invention has the following beneficial effects: the ginseng-astragalus-purple white tissue regeneration promoting paste is prepared by arranging compatibility according to the relationship of monarch, minister, assistant and guide, decocting, concentrating, sterilizing, cooling, standing and the like. The SHENQIZIBAISHENG paste is applied to affected part to remove necrotic tissue, astringe and promote granulation. Is suitable for skin defect, bedsore, and unhealed wound.
Drawings
FIG. 1 is a block flow diagram of an embodiment, which is mainly used for embodying a preparation method of a Shenqi Zibai Sheng muscle ointment;
FIG. 2 is a schematic sectional view of an embodiment, which is mainly used for embodying the internal structure of the decocting device;
FIG. 3 is a schematic structural diagram of the embodiment, which is mainly used for showing the structure of the blanking device;
fig. 4 is a schematic partial sectional view of the embodiment, which is mainly used for embodying the matching structure of the roller and the circular arc sheet.
In the figure, 101, a medicinal material cavity; 102. a decoction cavity; 103. a heating cavity; 2. an electric heating wire; 3. a feed inlet; 41. a motor; 42. a stirring shaft; 43. a paddle; 5. a liquid outlet; 601. a worm; 602. a worm gear; 603. a drum; 604. arc sheets; 605. a connecting rod; 606. a connecting plate; 607. a first filter hole; 608. a second filter hole; 609. a chute; 610. an annular tooth surface; 611. a gear; 612. a connecting shaft; 7. and (7) a cover plate.
Detailed Description
The invention is described in detail below with reference to the figures and examples.
It should be noted that the raw material components used in the embodiments of the present invention, such as radix astragali, radix angelicae, radix sanguisorbae, rhizoma bletillae, radix rehmanniae, radix arnebiae seu lithospermi, rhizoma paridis, borneol, sesame oil, vaseline, etc., are all commercially available products.
Example 1: a SHENQIZIBAISHENG paste for treating pressure injury is prepared from radix Codonopsis, radix astragali, fructus Lycii, and radix astragali by mixing, and making into ointment by conventional method: 8kg of astragalus; 4kg of Chinese angelica; 3kg of radix angelicae; 1kg of garden burnet; 1kg of bletilla striata; 5kg of radix rehmanniae; 4kg of lithospermum; 1kg of paris rhizome; 1kg of borneol; 5.25kg of sesame oil; and 36.75kg of vaseline.
Referring to fig. 1, the preparation method thereof includes the following steps:
s1, weighing
Weighing the raw materials according to the weight parts of the raw materials of the granulation promoting ointment;
s2 grinding Borneolum Syntheticum into powder
Grinding the weighed borneol into powder, and sieving the powder by a 40-mesh sieve to obtain borneol fine powder;
s3 preparation of tissue regeneration promoting ointment
Decocting the rest materials except Borneolum Syntheticum and adjuvants in water for 2 times with a decocting device, each time with strong fire (about 310 deg.C) until water is boiled, and then decocting with slow fire (about 160 deg.C) for 1.2 hr; then filtering, and merging the decoction to obtain filtrate; concentrating the filtrate at 80 deg.C, adding oleum Sesami and vaseline, sterilizing, cooling to below 60 deg.C, adding the above fine powder, mixing, stirring for 30min, and standing to obtain SHENQIZIBAISHENGJI ointment.
In the technical scheme, the traditional Chinese medicine comprises mollissima rhizome, radix astragali, borneol, garden burnet root, lithospermum, radix astragali, radix rehmanniae, sesame oil, vaseline and the like, wherein the mollissima rhizome has the functions of clearing heat, removing toxicity and broad-spectrum antibiosis, the radix astragali has the functions of inhibiting platelet aggregation and promoting generation of various blood cells, the borneol has the functions of clearing heat, removing toxicity, cooling blood, stopping bleeding, removing toxicity, healing sore, and the lithospermum has the functions of clearing heat, cooling blood, promoting blood circulation, removing toxicity and promoting eruption. The raw rehmannia root has the functions of clearing heat and cooling blood and stopping bleeding, the sesame oil has the functions of generating muscles, relieving pain, eliminating carbuncle and swelling and tonifying chapped skin, and the vaseline has the effects of moistening and protecting the skin.
Astragalus root has the functions of tonifying qi, expelling toxin, discharging pus and promoting tissue regeneration, and is a holy medicine for treating sore and carbuncle, wherein the astragalus root is mainly used for treating carbuncle and carbuncle for a long time and discharging pus and relieving pain in Yun (astragalus root) in Shennong Ben Cao Jing, and the astragalus root is used for generating blood, promoting tissue regeneration, expelling pus and supporting internally in the Ben Cao Yao. When the shenqi zibai tissue regeneration promoting ointment is used, a thick layer of liquefied necrotic tissue can be seen on the surface of a wound surface at the beginning of application and during dressing change, and after the necrotic tissue is removed, the fresh granulation tissue can grow rapidly from the bottom of the wound surface.
The Chinese herbal medicines are arranged and matched according to the relationship of monarch, minister, assistant and guide, and are decocted, concentrated, sterilized, cooled, kept stand and the like to obtain the ginseng-astragalus-purple white tissue regeneration promoting paste. The SHENQIZIBAISHENG paste is applied to affected part to remove necrotic tissue, astringe and promote granulation. Is suitable for skin defect, bedsore, and unhealed wound.
The Shenqi Zibai tissue regeneration promoting ointment provided by the invention is an externally applied Chinese patent medicine, and is mainly used for treating skin necrosis and defects of limbs and trunk in a small range caused by trauma, burns, scalds, bedsores, infection and the like, or poor local soft tissue activity, poor blood circulation and defects of a wound base, and no obvious bone, tendon and vascular nerve exposed wound. Achieves the aim of promoting wound healing by non-operative treatment. Promoting blood circulation, removing blood stasis, clearing away heat and toxic materials, removing putrefaction, and promoting granulation. Achieves the aim of promoting wound healing by non-operative treatment. The invention has reasonable formula, simple preparation process and low cost, has the advantages of promoting wound healing, shortening wound healing time and improving healing quality, does not generate scar contracture and hyperplasia after healing, greatly shortens course of disease and is worthy of clinical popularization.
Referring to fig. 2 to 4, the decocting apparatus includes a tank, a stirring device, and a discharging device. The tank body is in a square barrel shape and sequentially comprises a heating cavity 103, a decoction cavity 102 and a medicinal material cavity 101 from bottom to top. The heating cavity 103 and the decoction cavity 102 are separated by a partition board, and the heating wire 2 is arranged in the heating cavity 103 to heat the materials in the decoction cavity 102 and the medicinal material cavity 101. During the decoction process, the other raw materials except the borneol and the auxiliary materials are added into the medicinal material cavity 101, and then water is added to completely soak the medicinal materials in the water. The blanking device is located between the decoction cavity 102 and the medicinal material cavity 101 and is used for intercepting medicinal materials in the medicinal material cavity 101. In the process of adding water, water automatically enters the decoction cavity 102 through the blanking device, so that the decoction cavity 102 is filled with decoction water, and medicinal materials cannot enter the decoction cavity 102 under the interception of the blanking device and can only be decocted in the medicinal material cavity 101.
Referring to fig. 2-4, the stirring device is used for stirring the medicinal materials and the decoction in the medicinal material cavity 101, a liquid outlet 5 is arranged on one side of the bottom of the decoction cavity 102, and a feed inlet 3 is arranged on the medicinal material cavity 101. The top of the tank body is connected with a cover plate 7 through bolts, and the feed inlet 3 is arranged on one side of the middle part of the cover plate 7. The stirring device includes a motor 41, a stirring shaft 42, and a paddle 43. The motor 41 is installed in the center of the cover plate 7, the stirring shaft 42 is vertically arranged, the upper end of the stirring shaft penetrates through the cover plate 7 to be connected with an output shaft of the motor 41, and the lower end of the stirring shaft is close to the center of the bottom of the medicinal material cavity 101. The paddle 43 is an inclined blade type paddle, and the paddle 43 is installed on the stirring shaft 42 and is coaxially and rotatably arranged with the stirring shaft 42.
In the technical scheme, the invention adopts an electric heating mode, the decoction cavity 102 and the medicinal material cavity 101 are heated by the electric heating wire 2 in the heating cavity 103 at the bottom of the tank body, and the temperature is convenient to control. In addition, the decoction cavity 102 and the medicinal material cavity 101 are subjected to blanking control through the blanking device, so that the medicinal materials can be prevented from entering the decoction cavity 102, and therefore, after the Chinese medicines are decocted, only the decoction liquid needs to be discharged through the liquid outlet 5, and the medicinal materials can be remained in the medicinal material cavity 101, so that the filtering effect is achieved, and the use is simple and convenient. In order to fully decoct out the effective components in the medicinal materials, the stirring device is arranged, and when the motor 41 is started, the stirring shaft 42 drives the blades 43 to stir the materials.
Referring to fig. 2 to 4, the blanking device includes a drum 603, an annular tooth surface 610, a worm wheel 602, a worm 601, a gear 611, a connecting shaft 612, and a circular arc piece 604. Be provided with the feed opening between frying in shallow oil chamber 102 and the medicinal material chamber 101, cylinder 603 is installed in the feed opening and the upper portion of cylinder 603 circumferential surface is located medicinal material chamber 101, and circumferential surface's lower part is located frying in shallow oil chamber 102. The axial direction of roller 603 is perpendicular with (mixing) shaft 42 axial direction, and the both ends of roller 603 respectively with the lateral wall normal running fit of the relative both sides of jar body, and medicinal material chamber 101 lower part is and leaks hopper-shaped, and roller 603 is located medicinal material chamber 101 bottom center. The circumferential surface of the roller 603 is provided with a plurality of circular first filtering holes 607 for passing decoction, and the first filtering holes 607 are uniformly distributed on the circumferential surface of the roller 603.
Referring to fig. 2-4, the annular tooth surface 610 is sleeved on the roller 603 and fixedly connected with the circumferential surface of the roller 603, two annular tooth surfaces 610 are provided, and the two annular tooth surfaces 610 are symmetrically arranged at two sides of the middle part of the roller 603. The worm 601 is vertically arranged and fixed at the lower part of the stirring shaft 42, and the worm wheel 602 is positioned at one side of the worm 601 and meshed with the worm 601. Two ends of the connecting shaft 612 are respectively rotatably connected with the side part of the tank body, the connecting shaft 612 passes through the center of the worm wheel 602 and is coaxially and rotatably arranged with the worm wheel 602, and the worm wheel 602 is fixed in the middle of the connecting shaft 612. The gear 611 is fixed on the axial direction of the connecting shaft 612, the gear 611 is meshed with the annular tooth surface 610, specifically, two gears 611 are arranged, and the two gears 611 are symmetrically arranged on two sides of the worm wheel 602 and correspond to the two annular tooth surfaces 610 in position one by one. When the connecting shaft 612 rotates, the roller 603 will rotate around the central axis of the roller 603 at the feed opening.
In the above technical solution, in order to separate the decoction from the medicinal material, the drum 603 is provided in the present invention, under the interception of the drum 603, the medicinal material cannot pass through the first filtering hole 607 due to the large specific surface area, and thus cannot enter the decoction chamber 102 through the feed opening, and the decoction can quickly enter the decoction chamber 102 through the first filtering hole 607 and then is discharged through the liquid outlet 5. In the stirring process of the stirring device, the paddle 43 adopts an intermittent stirring mode, and the stirring is performed once every 5-10min approximately, and the stirring is performed for about 30s each time. After the decoction is finished, the motor 41 continues to operate until all the decoction is discharged. During the liquid discharging process, the motor 41 is started, the stirring shaft 42 drives the worm 601 to rotate, and because the worm 601 is meshed with the worm wheel 602, when the worm 601 rotates, the worm wheel 602 drives the connecting shaft 612 and the gear 611 to simultaneously rotate around the central axis of the connecting shaft 612. Since the gear 611 is engaged with the annular tooth surface 610, and the annular tooth surface 610 is fixed on the circumferential surface of the roller 603, when the gear 611 rotates, the annular tooth surface 610 will drive the roller 603 to rotate around the central axis of the roller 603. Because the roller 603 is always in the rotating process, the first filtering holes 607 corresponding to the feed opening are also always changed, so that the first filtering holes 607 are difficult to be blocked by the crushed medicinal material in the medicinal material cavity 101, even if some first filtering holes 607 are blocked with the crushed slag, when the first filtering holes 607 blocked with the crushed slag rotate to the lower part of the circumferential surface of the roller 603, the decocted fluid passes through the inner side of the roller 603 from the outer side, the crushed slag blocked in the first filtering holes 607 can be washed out, a better back washing effect is achieved, the roller 603 can be effectively prevented from being blocked, and the decocted fluid in the decocted fluid cavity 102 can not flow out.
Referring to fig. 2-4, the arc piece 604 is located in the decoction cavity 102 and located below and at the side of the circumferential surface of the roller 603, the inner arc surface of the arc piece 604 faces the roller 603, and the center of the arc piece 604 and the center of the roller 603 are located on the same straight line. The circular arc piece 604 is provided with a plurality of second filter holes 608, and the plurality of second filter holes 608 are uniformly distributed on the circular arc piece 604. The axial direction of the second filtering holes 608 is the same as the radial direction of the circular arc piece 604, and the aperture of the second filtering holes 608 is smaller than that of the first filtering holes 607. The arc piece 604 is fixed with a connecting rod 605, the roller 603 is fixed with a connecting plate 606, and the connecting plate 606 is connected with the connecting rod 605 through bolts, so that the arc piece 604 can be detached. Two ends of the arc piece 604 are respectively contacted with the side wall of the decoction cavity 102. The connection plate 606 is rotatably connected to the drum 603. Specifically, a chute 609 is formed in the circumferential surface of the drum 603, the chute 609 is a circular ring and is a T-shaped chute, the connecting plate 606 is matched with the chute 609, and the connecting plate 606 is embedded in the chute 609 and is in sliding fit with the chute 609. The roller 603 is provided with two sliding grooves 609, the two sliding grooves 609 are respectively close to two ends of the roller 603, two connecting plates 606 are symmetrically arranged on each sliding groove 609, a connecting rod 605 is arranged on each connecting plate 606, and the connecting rods 605 are fixed on the inner sides of the arc sheets 604 and located on two sides of the roller 603. The circular arc piece 604 is suspended below the drum 603 under the mating connection of the connection plate 606 and the connection rod 605.
In the above technical scheme, when the roller 603 rotates for blanking, the slag blocked in the first filtering hole 607 is carried out by the decoction back flush, so in order to prevent the slag carried out by the decoction from entering the decoction chamber 102, the circular arc piece 604 is provided in the invention, so that the decoction can pass through the circular arc piece 604 first after coming out of the roller 603, and the slag carried in the decoction can not pass through the second filtering hole 608, so as to be deposited in the circular arc piece 604, thereby achieving the effect of further filtering, and obtaining the high-quality decoction.
Example 2: compared with the embodiment 1, the ginseng and astragalus purple white tissue regeneration promoting paste for treating the pressure injury is characterized in that the formula of the ginseng and astragalus purple white tissue regeneration promoting paste is as follows: 6kg of astragalus; 2kg of Chinese angelica; 2kg of radix angelicae; 0.5kg of garden burnet; 0.5kg of bletilla striata; 3kg of radix rehmanniae; 2kg of lithospermum; 0.5kg of paris; 0.5kg of borneol; 5.25kg of sesame oil; 31.5kg of vaseline.
The preparation method comprises the following steps:
s1, weighing
Weighing the raw materials according to the weight parts of the raw materials of the granulation promoting ointment;
s2 grinding Borneolum Syntheticum into powder
Grinding the weighed borneol into powder, and sieving the powder by a 30-mesh sieve to obtain borneol fine powder;
s3 preparation of tissue regeneration promoting ointment
Decocting the rest materials except Borneolum Syntheticum and adjuvants in water for 2 times with a decocting device, each time with strong fire (about 310 deg.C) until water is boiled, and decocting with slow fire (about 160 deg.C) for 1 hr; then filtering, and merging the decoction to obtain filtrate; concentrating the filtrate at 80 deg.C, adding oleum Sesami and vaseline, sterilizing, cooling to below 60 deg.C, adding the above fine powder, mixing, stirring for 30min, and standing to obtain SHENQIZIBAISHENGJI ointment.
Example 3: compared with the embodiment 1, the ginseng and astragalus purple white tissue regeneration promoting paste for treating the pressure injury is characterized in that the formula of the ginseng and astragalus purple white tissue regeneration promoting paste is as follows: 10kg of astragalus; 5kg of Chinese angelica; 5kg of radix angelicae; 2kg of garden burnet; 2kg of bletilla striata; 7kg of radix rehmanniae; 5kg of lithospermum; 2kg of paris rhizome; 2kg of borneol; 5.25kg of sesame oil; 42kg of vaseline.
The preparation method comprises the following steps:
s1, weighing
Weighing the raw materials according to the weight parts of the raw materials of the granulation promoting ointment;
s2 grinding Borneolum Syntheticum into powder
Grinding the weighed borneol into powder, and sieving the powder by a 60-mesh sieve to obtain borneol fine powder;
s3 preparation of tissue regeneration promoting ointment
Decocting the rest materials except Borneolum Syntheticum and adjuvants in water for 2 times with a decocting device, each time with strong fire (about 310 deg.C) until water is boiled, and decocting with slow fire (about 160 deg.C) for 1 hr; then filtering, and merging the decoction to obtain filtrate; concentrating the filtrate at 80 deg.C, adding oleum Sesami and vaseline, sterilizing, cooling to below 60 deg.C, adding the above fine powder, mixing, stirring for 30min, and standing to obtain SHENQIZIBAISHENGJI ointment.
Examples of the applications
Case collection: data was collected from pressure-injured patients over the study period and randomized into 50 controls and observations, each at age 16-90 years, with controls P > 0.05.
The treatment method comprises the following steps: the observation group was coated with the shenqi zibai shengji ointment of example 1, and the control group was changed with conventional 0.9% NS for 2 weeks. After 2 weeks, the observation group and the control group were analyzed again.
The treatment effect is as follows: the observation group using the ginseng and astragalus purple-white tissue regeneration promoting paste for treatment carries out treatment effect evaluation according to the treatment effect evaluation standard, 46 cases are cured, accounting for 92 percent, 4 cases are improved, accounting for 8 percent, and the total effective rate is 100 percent. And the control group treated by using the conventional 0.9% NS is used for evaluating the treatment effect according to the treatment effect evaluation standard, 42 cases are cured, accounting for 84%, 6 cases are improved, accounting for 12%, and the total effective rate is 96%. Therefore, the efficacy of the ginseng and astragalus purple white tissue regeneration promoting paste is superior to that of the conventional 0.9% NS.
The above description is only a preferred embodiment of the present invention, and the protection scope of the present invention is not limited to the above embodiments, and all technical solutions belonging to the idea of the present invention belong to the protection scope of the present invention. It should be noted that several improvements and modifications without departing from the principle of the present invention will occur to those skilled in the art, and such improvements and modifications should also be construed as within the scope of the present invention.

Claims (10)

1. A ginseng and astragalus purple white tissue regeneration promoting paste for treating pressure injury is characterized in that: the feed comprises the following raw materials in parts by weight:
6-10 parts of astragalus;
2-5 parts of angelica;
2-5 parts of radix angelicae;
0.5-2 parts of garden burnet;
0.5-2 parts of bletilla striata;
3-7 parts of radix rehmanniae;
2-5 parts of lithospermum;
0.5-2 parts of paris;
0.5-2 parts of borneol;
36-70 parts of auxiliary materials.
2. The ginseng and astragalus purple white tissue regeneration promoting paste for treating pressure injury according to claim 1, wherein the paste is prepared from the following raw materials in parts by weight: the auxiliary materials comprise sesame oil and vaseline, wherein the mass ratio of the sesame oil to the vaseline is 1: (6-8).
3. The ginseng and astragalus purple white tissue regeneration promoting paste for treating pressure injury according to claim 2, wherein the paste is prepared from the following raw materials in parts by weight: the feed comprises the following raw materials in parts by weight:
8 parts of astragalus;
4 parts of angelica;
3 parts of radix angelicae;
1 part of garden burnet;
1 part of bletilla striata;
5 parts of radix rehmanniae;
4 parts of lithospermum;
1 part of paris rhizome;
1 part of borneol;
6 parts of sesame oil;
42 parts of auxiliary materials.
4. The preparation method of the shenqi zibai sheng paste for treating pressure injury as claimed in claim 1, wherein the preparation method comprises the following steps: the method comprises the following steps:
s1, weighing
Weighing the raw materials and the parts by weight of the tissue regeneration promoting paste according to any one of claims 1 to 3;
s2 grinding Borneolum Syntheticum into powder
Grinding the weighed borneol into powder, and sieving the powder by a sieve of 30-60 meshes to obtain borneol fine powder;
s3 preparation of tissue regeneration promoting ointment
Decocting the rest materials except Borneolum Syntheticum and adjuvants in water for 2 times with a decocting device, wherein each time, the materials are first decocted with strong fire until water is boiling, and then decocted with slow fire for 1-1.5 hr; then filtering, and merging the decoction to obtain filtrate; concentrating the filtrate at 80 deg.C, adding adjuvants, sterilizing, adding the above Borneolum fine powder when the temperature is reduced to below 60 deg.C, mixing, stirring for 25-40min, and standing to obtain SHENQIZIBAOSHENG ointment.
5. The preparation method of the SHENQIZIBAISHEN paste for treating pressure injury according to claim 4, which comprises: the decocting device comprises a tank body, a stirring device and a blanking device, the tank body sequentially comprises a heating cavity (103), a decoction cavity (102) and a medicinal material cavity (101) from bottom to top, and the blanking device is positioned between the decoction cavity (102) and the medicinal material cavity (101) and is used for intercepting medicinal materials in the medicinal material cavity (101); the stirring device is used for stirring medicinal materials and decoction in the medicinal material cavity (101); a liquid outlet (5) is arranged on the decoction cavity (102), and a feed inlet (3) is arranged on the medicinal material cavity (101).
During the decoction process, the other raw materials except the borneol and the auxiliary materials are added into the medicinal material cavity (101), and then water is added to soak the medicinal materials in the water.
6. The preparation method of the SHENQIZIBAISHEN paste for treating pressure injury according to claim 5, which comprises: the stirring device comprises a motor (41), a stirring shaft (42) and a blade (43);
a cover plate (7) is arranged at the top of the medicinal material cavity (101), the motor (41) is installed in the center of the cover plate (7), the stirring shaft (42) is vertically arranged, the upper end of the stirring shaft penetrates through the cover plate (7) to be connected with an output shaft of the motor (41), and the lower end of the stirring shaft is close to the center of the bottom of the medicinal material cavity (101);
the blades (43) are arranged on the stirring shaft (42) and are coaxially and rotatably arranged with the stirring shaft (42).
7. The preparation method of the SHENQIZIBAISHEN paste for treating pressure injury according to claim 6, which comprises: the blanking device comprises a roller (603), an annular tooth surface (610), a worm wheel (602), a worm (601), a gear (611) and a connecting shaft (612);
a feed opening is formed between the decoction cavity (102) and the medicinal material cavity (101), the roller (603) is installed in the feed opening, the upper part of the circumferential surface of the roller (603) is located in the medicinal material cavity (101), the lower part of the circumferential surface is located in the decoction cavity (102), the axial direction of the roller (603) is vertical to the axial direction of the stirring shaft (42), and the roller (603) is rotatably connected to the tank body; the circumferential surface of the roller (603) is provided with a first filtering hole (607) for passing through the decoction;
the annular tooth surface (610) is sleeved on the roller (603) and fixedly connected with the circumferential surface of the roller (603), the worm (601) is fixed at the lower part of the stirring shaft (42), the worm wheel (602) is positioned at one side of the worm (601) and meshed with the worm (601), two ends of the connecting shaft (612) are rotatably connected with the side part of the tank body, and the middle part of the connecting shaft penetrates through the center of the worm wheel (602) and is coaxially and rotatably arranged with the worm wheel (602);
the gear (611) is fixed on the axial direction of the connecting shaft (612), and the gear (611) is meshed with the annular tooth surface (610), so that when the connecting shaft (612) rotates, the roller (603) rotates around the central shaft of the roller (603) at the feed opening.
8. The preparation method of the paste for promoting tissue regeneration of ginseng, astragalus, purple peony and white tissue for treating pressure injury according to claim 7, wherein the paste comprises the following components: unloader still includes circular arc piece (604), circular arc piece (604) are located fry in shallow oil chamber (102) and be located cylinder (603) circumferential surface's below and lateral part, circular arc piece (604) intrados orientation cylinder (603), circular arc piece (604) are last to have seted up second and have strained hole (608), the aperture that second strained hole (608) is less than the aperture of first filtration hole (607).
9. The method for preparing SHENQIZIBAISHEN paste for treating pressure injury according to claim 8, which comprises: a connecting rod (605) is fixed on the arc sheet (604), a connecting plate (606) is fixed on the roller (603), the connecting plate (606) is connected with the connecting rod (605) through a bolt, and the connecting plate (606) is rotationally connected to the roller (603).
10. The method for preparing SHENQIZIBAISHEN paste for treating pressure injury as claimed in claim 9, wherein the paste is prepared by mixing radix Codonopsis, radix astragali, radix Angelicae sinensis, radix astragali, radix: the surface of the circumference of the roller (603) is provided with a sliding groove (609), the sliding groove (609) is a circular ring and is a T-shaped sliding groove, the connecting plate (606) is matched with the sliding groove (609), and the connecting plate (606) is embedded in the sliding groove (609) and is in sliding fit with the sliding groove (609).
CN202010867891.6A 2020-08-26 2020-08-26 Ginseng and astragalus purple white tissue regeneration promoting paste for treating pressure injury and preparation method thereof Pending CN111939227A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010867891.6A CN111939227A (en) 2020-08-26 2020-08-26 Ginseng and astragalus purple white tissue regeneration promoting paste for treating pressure injury and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010867891.6A CN111939227A (en) 2020-08-26 2020-08-26 Ginseng and astragalus purple white tissue regeneration promoting paste for treating pressure injury and preparation method thereof

Publications (1)

Publication Number Publication Date
CN111939227A true CN111939227A (en) 2020-11-17

Family

ID=73367498

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202010867891.6A Pending CN111939227A (en) 2020-08-26 2020-08-26 Ginseng and astragalus purple white tissue regeneration promoting paste for treating pressure injury and preparation method thereof

Country Status (1)

Country Link
CN (1) CN111939227A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112717065A (en) * 2021-02-25 2021-04-30 广州中医药大学第一附属医院 A Chinese medicinal liniment for treating pressure injury, and its preparation method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN204522456U (en) * 2015-04-03 2015-08-05 重庆奥力生物制药有限公司 Solid-liquid separating machine
CN104857301A (en) * 2015-05-25 2015-08-26 李海坤 Moisturizing and flesh-engendering ointment for treating bedsores
CN110624035A (en) * 2019-11-12 2019-12-31 徐立明 Ziqi tissue regeneration promoting paste

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN204522456U (en) * 2015-04-03 2015-08-05 重庆奥力生物制药有限公司 Solid-liquid separating machine
CN104857301A (en) * 2015-05-25 2015-08-26 李海坤 Moisturizing and flesh-engendering ointment for treating bedsores
CN110624035A (en) * 2019-11-12 2019-12-31 徐立明 Ziqi tissue regeneration promoting paste

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112717065A (en) * 2021-02-25 2021-04-30 广州中医药大学第一附属医院 A Chinese medicinal liniment for treating pressure injury, and its preparation method
CN112717065B (en) * 2021-02-25 2022-05-06 广州中医药大学第一附属医院 A Chinese medicinal liniment for treating pressure injury, and its preparation method

Similar Documents

Publication Publication Date Title
CN102319350B (en) External scald oil medicinal composition for treating burns and scalds
CN1051237C (en) Meicinal prepn. "Kexianling" for curing epilepsy
CN102579755A (en) Chinese medicinal formula for treating chronic renal failure
CN105031307A (en) Chinese drugs preparation for curing headache and preparation method for Chinese drugs pharmaceutics
CN111939227A (en) Ginseng and astragalus purple white tissue regeneration promoting paste for treating pressure injury and preparation method thereof
CN101112603A (en) Cardiac and cerebral vascular disease treating medicine and method for preparing the same
CN101143171A (en) Traditional Chinese medicine and its preparation method and its application
CN1239177C (en) Chinese herbal medicine for treating piles
CN103919952A (en) Gel preparation for treating hemorrhoids and preparation method thereof
CN1177599C (en) Chinese medicine for treating burn and scald and its preparing process
CN100411666C (en) Broad-specturm medicine for treating snake venom poisoning
CN105770487A (en) Traditional Chinese medicine composition for treating cerebral infarction and cerebral hemorrhage sequelae and preparation method thereof
CN1236804C (en) Making method of capsule for treating hemorrhoid
CN1907318A (en) Use of ceylon houndstongue and pharmaceutical composition containing same
CN1075726C (en) Oral liquid for treatment of heart disease and its prepn. method
CN115919983B (en) Pharmaceutical composition for treating or assisting in treating frequent urination, preparation method and device
CN1269499C (en) Medicine efficacious for burn and preparation method
CN101721610B (en) Medicine for treating tumors
CN101401905B (en) Chinese medicinal composition for treating aplastic anemia
CN111939221A (en) Jianbu pills for late fracture and preparation method thereof
CN111803582A (en) Preparation method of traditional Chinese medicine packet for treating psoriasis
CN111012886A (en) Medicine for treating liver cancer and preparation method thereof
CN1383851A (en) Lung cancer treating medicine and its prepn
CN1301130C (en) Hepatic calculus dissolving solution
CN116570699A (en) Traditional Chinese medicine composition for treating pulmonary nodules as well as preparation and application thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20201117

RJ01 Rejection of invention patent application after publication