CN108721478A - A kind of plant multi-effect compound agent of mosquito-proof sting - Google Patents
A kind of plant multi-effect compound agent of mosquito-proof sting Download PDFInfo
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- CN108721478A CN108721478A CN201811057347.4A CN201811057347A CN108721478A CN 108721478 A CN108721478 A CN 108721478A CN 201811057347 A CN201811057347 A CN 201811057347A CN 108721478 A CN108721478 A CN 108721478A
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- 239000001198 melaleuca alternifolia leaf oil Substances 0.000 claims description 2
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- PYKYMHQGRFAEBM-UHFFFAOYSA-N anthraquinone Natural products CCC(=O)c1c(O)c2C(=O)C3C(C=CC=C3O)C(=O)c2cc1CC(=O)OC PYKYMHQGRFAEBM-UHFFFAOYSA-N 0.000 description 1
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A—HUMAN NECESSITIES
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Biotechnology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Organic Chemistry (AREA)
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of plant multi-effect compound agent of mosquito-proof sting, the component and mass content of the plant multi-effect compound agent of the mosquito-proof sting are as follows：1.5-3.7 parts of tea tree ethereal oil, 0.8-2.5 parts of Flos Lonicerae extractive solution, 2.8-6.7 parts of Cremophor RH40,26-42 parts of ethyl alcohol, 0.1-0.32 parts of menthol, 0.2-0.55 parts of borneol, 6.7-12.0 parts of fresh fructus lycii extracting solution, 11.5-17.5 parts of wild chrysanthemum extracting solution, 4.3-8.5 parts of extract solution from aloe, 15-29 parts of deionized water；Plant multi-effect compound agent of the mosquito-proof sting and preparation method thereof, formula is reasonable, prepares simply, the quality of the plant multi-effect compound agent of mosquito-proof sting is good, and conducive to making full use of for each raw material, while function is a variety of.
Description
Technical field
The invention belongs to the field of pharmaceutical technology of mosquito-proof sting, more specifically more particularly to a kind of mosquito-proof sting
Plant multi-effect compound agent.
Background technology
During the broiling summer, people generally wear thin, and coat-sleeve is shorter or even smooth dew skin.And mosquito, belong to this inflammation
The season of heat.Murder is mentioned, possible no one is it is contemplated that mosquito.In everybody the most fierce and cruel shark of impression, annual murder quantity is not
Cross 10 people.Even the mankind all to kill each other daily, murder quantity is all far away from this " miniature killing machine " --- mosquito.Root
It is shown according to the investigation of WHO (World Health Organization), mosquito is to kill the most animal of the mankind, every year up to 72.5 ten thousand people.2015
This year in year, because the number of mosquito death is risen unexpectedly to 830,000 people.In our daily lifes, those are ubiquitous and annoying
Mosquito is only and endangers maximum animal in the world.
The mosquito sucked blood is the vector of the other pathogens such as dengue fever, malaria, yellow fever, filariasis, encephalitis B.
Dermatitis caused by bite by mosquitos is most common in insect dermatitis.Mosquito stabs skin, saliva or venom by its mouthpart
Skin is invaded, since, containing there are many antigenic component, these antigens are entering human body skin in the saliva of mosquito or the leachate of poison gland
Allergic reaction can be generated after skin with antibody and causes inflammation.
In order to alleviate the discomfort generated due to bite by mosquitos, people through being treated frequently with following prescription, with mitigate by
In bite by mosquitos bring itch, pain etc. symptoms：
Chinese patent application 201510322218.3 discloses a kind of external prescription for controlling bite by mosquitos, recipe ingredient and each
It is from weight：Fresh fructus lycii leaf is several.It is a kind of external prescription for controlling bite by mosquitos, is suitable for by the bite by mosquitos the wounded, tool
There are antibacterial, anti-inflammatory, scar and other effects of dispelling, can greatly speed up and normal process is restored by injured red and swollen skin after bite by mosquitos.
Chinese patent application 201110240439.8 discloses a kind of composition for bite by mosquitos, the group of bite by mosquitos
Object is closed to be made of following raw materials according by weight：5~10 parts of folium artemisiae argyi, 5~10 parts of Chinese prickly ash, 10~15 parts of peppermint, 10~15 parts of wrinkled giant hyssop.Examination
It verifies bright, has the function of clearing heat and detoxicating, antipruritic analgesic well for the composition of bite by mosquitos.Its is easy to use, takes effect
Soon, safe, have no toxic side effect.
Chinese patent application 201710396571.5 discloses a kind of medicament for treating bite by mosquitos, by the original of following weight
Material is made：10~15 grams of tea oil, 1~2 gram of Folium Artemisiae Argyi extractive liquid, 0.2~0.5 gram of glutinous rice flour.The treatment mosquito of the technical solution stings
The medicament stung have treatment bite by mosquitos effect it is good, it is non-stimulated, nontoxic it is erasable be coated on the sensitive skins such as eyes and mouth edge, and
And manufacture craft is simple, at low cost, is suitable for promoting.
Although what above-mentioned medicament in the prior art can mitigate that bite by mosquitos brings well to a certain extent itch, pain etc.
Symptom, but bite by mosquitos cannot be prevented, the harm for making people that bite by mosquitos be avoided to bring.
Invention content
The purpose of the present invention is to solve the deficiencies in the prior art, traditional summer treats the medicine of bite by mosquitos
Agent, effect is single, the problem of cannot preventing bite by mosquitos, and a kind of plant multi-effect compound agent of the mosquito-proof sting proposed.
To achieve the above object, the present invention provides the following technical solutions：
A kind of plant multi-effect compound agent of mosquito-proof sting, the component of the plant multi-effect compound agent of the mosquito-proof sting with
And mass content is as follows：1.5-3.7 parts of tea tree ethereal oil, 0.8-2.5 parts of Flos Lonicerae extractive solution, Cremophor RH40 2.8-
6.7 parts, 26-42 parts of ethyl alcohol, 0.1-0.32 parts of menthol, 0.2-0.55 parts of borneol, 6.7-12.0 parts of fresh fructus lycii extracting solution, mother chrysanthemum
11.5-17.5 parts of extracting solution of flower, 4.3-8.5 parts of extract solution from aloe, 15-29 parts of deionized water.
Preferably, the plant multi-effect compound agent of the mosquito-proof sting further includes 0.17-0.38 parts of xanthans, allantoin
0.25-0.74 parts.
Preferably, the tea tree ethereal oil is Melaleuca alternifolia leaf oil.
Preferably, in order to upset the normal physiological of mosquito nerve, it is allowed to dead by excited, spasm to paralysis, and prevent
Any excess drug generates harm to people and animals, reduces the pollution of environment, the plant multi-effect compound agent of the mosquito-proof sting further includes removing
7.5-18.5 parts of worm pyrethroids.
Preferably, in order to make mosquito be maintained a certain distance with human body, biting for mosquito is prevented, and mitigate pyrethrins pair
The harm of human body, the plant multi-effect compound agent of the mosquito-proof sting further include further include fresh wormwood extract 3.4-8.4 parts.
Preferably, in the plant multi-effect compound agent of above-mentioned mosquito-proof sting, the fresh wormwood extract and pyrethrins,
Promote mutually；On the one hand, fresh wormwood extract can mitigate harm of the pyrethrins to human body, on the other hand, pyrethrins energy
The release for enough promoting fresh wormwood extract improves its drug effect.Further, the content M2 of the fresh wormwood extract and Dalmatian chrysanthemum
Ester M1 meets M1M2 and is less than or equal to 123.8 more than or equal to 28.5.
Preferably, the production method of the tea tree ethereal oil is：First tea tree is cleaned, then crushes and is soaked in water 10 minutes,
Then it is squeezed out come essential oil liquid by squeezer, then by purification bottling, the Cremophor RH40 is with equally
Method be made.
Preferably, the production method of the Flos Lonicerae extractive solution is：First honeysuckle is cleaned, then crushes and is soaked in water 10
Minute, it is then squeezed out come liquid by squeezer, then by purification bottling, the wild chrysanthemum extracting solution, aloe carry
Liquid and menthol is taken to be made by identical method.
Preferably, the menthol in the leaf and stem of peppermint by being extracted.
In order to preferably prepare the plant multi-effect compound agent of above-mentioned mosquito-proof sting, a kind of mosquito proof provided by the invention
The preparation method for the plant multi-effect compound agent bitten, includes the following steps：
S1, stock：Prepare above-mentioned raw materials according to component and content；
S2, heating：Deionized water, xanthans, allantoin are added in blender, starts blender and heating temperature W1 is arrived
It 75-95 DEG C, is uniformly mixed, and soaking time T1 is 15-20 minutes；
S3, batch mixing：The rotating speed of blender is improved, and after being cooled to 50 DEG C, Cremophor RH40, alternate leaf is white
Thousand layers of leaf oil, ethyl alcohol, menthol, borneol, Flos Lonicerae extractive solution, wild chrysanthemum extracting solution, extract solution from aloe, which are added in blender, to be added
Heat is 55-72 DEG C to temperature W2, is uniformly mixed；
S4, cooling：Stop blender, and is cooled to room temperature；
S5, detection：It discharges after detection is qualified.
Preferably, the blender is digital display constant temperature blender with magnetic force.
Preferably, the blender rotating speed R1 described in S2 is 50-70r/min.
Preferably, it is 80-100r/min that the blender rotating speed described in S4, which is increased to R2,.
Preferably, each ingredient in the plant multi-effect compound agent in order to make above-mentioned mosquito-proof sting is uniformly mixed, described
Rotating speed R1, R2, heating temperature W1 and soaking time T1 meet following relationship：
R1/R2=α (W2/W1) T11/2；
Wherein, α is balance factor, value range 0.13-0.36.
Preferably, prevent bite by mosquitos, and energy to more fully play the plant multi-effect compound agent of mosquito-proof sting
Enough effects that analgesic antiphlogistic of itching is played after bite by mosquitos, the content M2 and pyrethrins M1 of the fresh wormwood extract and plus
Hot temperature W1, soaking time T1 meet following relationship：
M1M2=γ (W12/T1)；
Wherein, γ is adjustment factor, value range 0.18-0.76.
Compared with prior art, technique effect of the invention and advantage：
1, the plant multi-effect compound agent of the mosquito-proof sting, formula is reasonable, the plant multi-effect compound agent of mosquito-proof sting
Quality is good, and conducive to making full use of for each raw material, while function is a variety of.
2, the plant multi-effect compound agent of the mosquito-proof sting upsets the normal life of mosquito nerve by choosing pyrethrins
Reason is allowed to dead by excited, spasm to paralysis, and prevents any excess drug from generating harm to people and animals, reduces the pollution of environment.
3, the plant multi-effect compound agent of the mosquito-proof sting makes mosquito be kept with human body by choosing fresh wormwood extract
A certain distance prevents biting for mosquito, and mitigates harm of the pyrethrins to human body.
4, the plant multi-effect compound agent of the mosquito-proof sting, by content M2 and pyrethrins that fresh wormwood extract is arranged
The relationship that M1 meets, fresh wormwood extract and pyrethrins promote mutually；On the one hand, fresh wormwood extract can mitigate deinsectization
Harm of the pyrethroids to human body, on the other hand, pyrethrins can promote the release of fresh wormwood extract, improve its drug effect.
Specific implementation mode
In order to make the purpose , technical scheme and advantage of the present invention be clearer, below in conjunction with specific embodiment, to this
Invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, not
For limiting the present invention.Based on the embodiments of the present invention, those of ordinary skill in the art are not before making creative work
The every other embodiment obtained is put, shall fall within the protection scope of the present invention.
Embodiment 1
A kind of plant multi-effect compound agent of mosquito-proof sting, the component of the plant multi-effect compound agent of the mosquito-proof sting with
And mass content is as follows：1.5-3.7 parts of tea tree ethereal oil, 0.8-2.5 parts of Flos Lonicerae extractive solution, Cremophor RH40 2.8-
6.7 parts, 26-42 parts of ethyl alcohol, 0.1-0.32 parts of menthol, 0.2-0.55 parts of borneol, 6.7-12.0 parts of fresh fructus lycii extracting solution, mother chrysanthemum
11.5-17.5 parts of extracting solution of flower, 4.3-8.5 parts of extract solution from aloe, 15-29 parts of deionized water.
The plant multi-effect compound agent of the mosquito-proof sting further includes 0.17-0.38 parts of xanthans, allantoin 0.25-0.74
Part.
In order to upset the normal physiological of mosquito nerve, it is allowed to dead by excited, spasm to paralysis, and prevent any excess drug
Harm is generated to people and animals, reduces the pollution of environment, the plant multi-effect compound agent of the mosquito-proof sting further includes pyrethrins
7.5-18.5 part.
In order to make mosquito be maintained a certain distance with human body, biting for mosquito is prevented, and mitigate pyrethrins to human body
Harm, the plant multi-effect compound agent of the mosquito-proof sting further include further include fresh wormwood extract 3.4-8.4 parts.
In the plant multi-effect compound agent of above-mentioned mosquito-proof sting, the fresh wormwood extract and pyrethrins promote mutually
Into；On the one hand, fresh wormwood extract can mitigate harm of the pyrethrins to human body, and on the other hand, pyrethrins can promote
The release of fresh wormwood extract improves its drug effect.Further, the content M2 and pyrethrins M1 of the fresh wormwood extract are full
Sufficient M1M2 is more than or equal to 28.5 and is less than or equal to 123.8.
The production method of the tea tree ethereal oil is：First tea tree is cleaned, then crushes and is soaked in water 10 minutes, then pass through
Squeezer, which squeezes out, carrys out essential oil liquid, then by purification bottling, the same method system of the Cremophor RH40
?.
The production method of the Flos Lonicerae extractive solution is：First honeysuckle is cleaned, then crushes and is soaked in water 10 minutes, so
It is squeezed out afterwards come liquid by squeezer, then by purification bottling, the wild chrysanthemum extracting solution, extract solution from aloe and thin
Lotus brain is made by identical method.
The menthol in the leaf and stem of peppermint by being extracted.
A kind of preparation method of the plant multi-effect compound agent of mosquito-proof sting provided by the invention, includes the following steps：
S1, stock：Prepare above-mentioned raw materials according to component and content；
S2, heating：Deionized water, xanthans, allantoin are added in blender, starts blender and heating temperature W1 is arrived
It 75-95 DEG C, is uniformly mixed, and soaking time T1 is 15-20 minutes；
S3, batch mixing：The rotating speed of blender is improved, and after being cooled to 50 DEG C, Cremophor RH40, alternate leaf is white
Thousand layers of leaf oil, ethyl alcohol, menthol, borneol, Flos Lonicerae extractive solution, wild chrysanthemum extracting solution, extract solution from aloe, which are added in blender, to be added
Heat is 55-72 DEG C to temperature W2, is uniformly mixed；
S4, cooling：Stop blender, and is cooled to room temperature；
S5, detection：It discharges after detection is qualified.
The blender is digital display constant temperature blender with magnetic force.
The blender rotating speed R1 described in S2 is 50-70r/min.
It is 80-100r/min that the blender rotating speed described in S4, which is increased to R2,.
Each ingredient in plant multi-effect compound agent in order to make above-mentioned mosquito-proof sting is uniformly mixed, the rotating speed
R1, R2, heating temperature W1 and soaking time T1 meet following relationship：
R1/R2=α (W2/W1) T11/2；
Wherein, α is balance factor, value range 0.13-0.36.
Plant multi-effect compound agent in order to more fully play mosquito-proof sting prevents bite by mosquitos, and can be in mosquito
The effect for analgesic antiphlogistic of itching, content M2 and pyrethrins M1 and the heating temperature of the fresh wormwood extract are played after biting
W1, soaking time T1 meet following relationship：
M1M2=γ (W12/T1)；
Wherein, γ is adjustment factor, value range 0.18-0.76.
Embodiment 2
A kind of plant multi-effect compound agent of mosquito-proof sting, the component of the plant multi-effect compound agent of the mosquito-proof sting with
And mass content is as follows：1.5 parts of tea tree ethereal oil, 0.8 part of Flos Lonicerae extractive solution, 2.8 parts of Cremophor RH40, ethyl alcohol 26
Part, 0.1 part of menthol, 0.2- parts of borneol, 6.7 parts of fresh fructus lycii extracting solution, 11.5 parts of wild chrysanthemum extracting solution, extract solution from aloe 4.3
Part, 15 parts of deionized water.
The plant multi-effect compound agent of the mosquito-proof sting further includes 0.17 part of xanthans, 0.25 part of allantoin.
In order to upset the normal physiological of mosquito nerve, it is allowed to dead by excited, spasm to paralysis, and prevent any excess drug
Harm is generated to people and animals, reduces the pollution of environment, the plant multi-effect compound agent of the mosquito-proof sting further includes pyrethrins 7.5
Part.
In order to make mosquito be maintained a certain distance with human body, biting for mosquito is prevented, and mitigate pyrethrins to human body
Harm, the plant multi-effect compound agent of the mosquito-proof sting further include further include 3.4 parts of fresh wormwood extract.
The production method of the tea tree ethereal oil is：First tea tree is cleaned, then crushes and is soaked in water 10 minutes, then pass through
Squeezer, which squeezes out, carrys out essential oil liquid, then by purification bottling, the same method system of the Cremophor RH40
?.
The production method of the Flos Lonicerae extractive solution is：First honeysuckle is cleaned, then crushes and is soaked in water 10 minutes, so
It is squeezed out afterwards come liquid by squeezer, then by purification bottling, the wild chrysanthemum extracting solution, extract solution from aloe and thin
Lotus brain is made by identical method.
The menthol in the leaf and stem of peppermint by being extracted.
A kind of preparation method of the plant multi-effect compound agent of mosquito-proof sting provided by the invention, includes the following steps：
S1, stock：Prepare above-mentioned raw materials according to component and content；
S2, heating：Deionized water, xanthans, allantoin are added in blender, starts blender and heating temperature W1 is arrived
It 75-95 DEG C, is uniformly mixed, and soaking time T1 is 15-20 minutes；
S3, batch mixing：The rotating speed of blender is improved, and after being cooled to 50 DEG C, Cremophor RH40, alternate leaf is white
Thousand layers of leaf oil, ethyl alcohol, menthol, borneol, Flos Lonicerae extractive solution, wild chrysanthemum extracting solution, extract solution from aloe, which are added in blender, to be added
Heat is 55-72 DEG C to temperature W2, is uniformly mixed；
S4, cooling：Stop blender, and is cooled to room temperature；
S5, detection：It discharges after detection is qualified.
The blender is digital display constant temperature blender with magnetic force.
The blender rotating speed R1 described in S2 is 50-70r/min.
It is 80-100r/min that the blender rotating speed described in S4, which is increased to R2,.
Each ingredient in plant multi-effect compound agent in order to make above-mentioned mosquito-proof sting is uniformly mixed, the rotating speed
R1, R2, heating temperature W1 and soaking time T1 meet following relationship：
R1/R2=α (W2/W1) T11/2；
Wherein, α is balance factor, value range 0.13-0.36.
Embodiment 3
A kind of plant multi-effect compound agent of mosquito-proof sting, the component of the plant multi-effect compound agent of the mosquito-proof sting with
And mass content is as follows：3.7 parts of tea tree ethereal oil, 2.5 parts of Flos Lonicerae extractive solution, 6.7 parts of Cremophor RH40, ethyl alcohol 42
Part, 0.32 part of menthol, 0.55 part of borneol, 12.0 parts of fresh fructus lycii extracting solution, 17.5 parts of wild chrysanthemum extracting solution, extract solution from aloe
8.5 parts, 29 parts of deionized water.
The plant multi-effect compound agent of the mosquito-proof sting further includes 0.38 part of xanthans, 0.74 part of allantoin.
In order to upset the normal physiological of mosquito nerve, it is allowed to dead by excited, spasm to paralysis, and prevent any excess drug
Harm is generated to people and animals, reduces the pollution of environment, the plant multi-effect compound agent of the mosquito-proof sting further includes pyrethrins
18.5 parts.
In order to make mosquito be maintained a certain distance with human body, biting for mosquito is prevented, and mitigate pyrethrins to human body
Harm, the plant multi-effect compound agent of the mosquito-proof sting further include further include 8.4 parts of fresh wormwood extract.
In the plant multi-effect compound agent of above-mentioned mosquito-proof sting, the fresh wormwood extract and pyrethrins promote mutually
Into；On the one hand, fresh wormwood extract can mitigate harm of the pyrethrins to human body, and on the other hand, pyrethrins can promote
The release of fresh wormwood extract improves its drug effect.Further, the content M2 and pyrethrins M1 of the fresh wormwood extract are full
Sufficient M1M2 is more than or equal to 28.5 and is less than or equal to 123.8.
The production method of the tea tree ethereal oil is：First tea tree is cleaned, then crushes and is soaked in water 10 minutes, then pass through
Squeezer, which squeezes out, carrys out essential oil liquid, then by purification bottling, the same method system of the Cremophor RH40
?.
The production method of the Flos Lonicerae extractive solution is：First honeysuckle is cleaned, then crushes and is soaked in water 10 minutes, so
It is squeezed out afterwards come liquid by squeezer, then by purification bottling, the wild chrysanthemum extracting solution, extract solution from aloe and thin
Lotus brain is made by identical method.
The menthol in the leaf and stem of peppermint by being extracted.
A kind of preparation method of the plant multi-effect compound agent of mosquito-proof sting provided by the invention, includes the following steps：
S1, stock：Prepare above-mentioned raw materials according to component and content；
S2, heating：Deionized water, xanthans, allantoin are added in blender, starts blender and heating temperature W1 is arrived
It 75-95 DEG C, is uniformly mixed, and soaking time T1 is 15-20 minutes；
S3, batch mixing：The rotating speed of blender is improved, and after being cooled to 50 DEG C, Cremophor RH40, alternate leaf is white
Thousand layers of leaf oil, ethyl alcohol, menthol, borneol, Flos Lonicerae extractive solution, wild chrysanthemum extracting solution, extract solution from aloe, which are added in blender, to be added
Heat is 55-72 DEG C to temperature W2, is uniformly mixed；
S4, cooling：Stop blender, and is cooled to room temperature；
S5, detection：It discharges after detection is qualified.
The blender is digital display constant temperature blender with magnetic force.
The blender rotating speed R1 described in S2 is 50-70r/min.
It is 80-100r/min that the blender rotating speed described in S4, which is increased to R2,.
Each ingredient in plant multi-effect compound agent in order to make above-mentioned mosquito-proof sting is uniformly mixed, the rotating speed
R1, R2, heating temperature W1 and soaking time T1 meet following relationship：
R1/R2=α (W2/W1) T11/2；
Wherein, α is balance factor, value range 0.13-0.36.
In summary：A kind of plant multi-effect compound agent and preparation method thereof of mosquito-proof sting provided by the invention, passes through
After the sequence of operations such as stock, heating, batch mixing, cooling, detection, the plant multiple-effect that can be made into mosquito-proof sting best in quality is multiple
Mixture；Tea tree ethereal oil belongs to plant origin, has effects that characteristic perfume and antibacterial, anti-inflammatory, expelling parasite, mite killing；Menthol is by thin
Extracted in the leaf and stem of lotus, be peppermint and Peppermint essential oil in main component, act on skin play the role of it is refrigerant antipruritic；
Flos Lonicerae extractive solution belongs to plant origin, has the function of anti-inflammatory, antibacterial；Wild chrysanthemum extracting solution belongs to plant origin, has anti-
Bacterium is antiviral, heat clearing and inflammation relieving, removing toxic substances effect；Anthraquinone analog compound in extract solution from aloe have make skin contraction, softness,
The performance of moisturizing, anti-inflammatory, while scytitis can also be treated, also have very well to acne, acne and scald, knife wound, insect bite etc.
The effect of；It in heating and the step of batch mixing, heats while stirring, it is uniform to be conducive to each dissolution of raw material, is conducive to each original
Material makes full use of.
Therefore the plant multi-effect compound agent and preparation method thereof of the mosquito-proof sting, formula is reasonable, prepares simple, mosquito proof
The quality for the plant multi-effect compound agent bitten is good, and conducive to making full use of for each raw material, while function is a variety of.
Finally it should be noted that：The foregoing is only a preferred embodiment of the present invention, is not intended to restrict the invention,
Although the present invention is described in detail referring to the foregoing embodiments, for those skilled in the art, still may be used
With technical scheme described in the above embodiments is modified or equivalent replacement of some of the technical features,
All within the spirits and principles of the present invention, any modification, equivalent replacement, improvement and so on should be included in the present invention's
Within protection domain.
Claims (6)
1. a kind of plant multi-effect compound agent of mosquito-proof sting, it is characterised in that：The plant multiple-effect of the mosquito-proof sting is compound
Agent is grouped as follows with mass percent each group：1.5-3.7 parts of tea tree ethereal oil, 0.8-2.5 parts of Flos Lonicerae extractive solution, PEG-40 hydrogen
Change 2.8-6.7 parts of castor oil, 26-42 parts of ethyl alcohol, 0.1-0.32 parts of menthol, 0.2-0.55 parts of borneol, fresh fructus lycii extracting solution
6.7-12.0 parts, 11.5-17.5 parts of wild chrysanthemum extracting solution, 4.3-8.5 parts of extract solution from aloe, 15-29 parts of deionized water.
2. a kind of plant multi-effect compound agent of mosquito-proof sting according to claim 1, it is characterised in that：The mosquito proof
The plant multi-effect compound agent bitten further includes 0.17-0.38 parts of xanthans, 0.25-0.74 parts of allantoin.
3. a kind of plant multi-effect compound agent of mosquito-proof sting according to claim 1 or 2, it is characterised in that：The tea
Tree essential oil is Melaleuca alternifolia leaf oil.
4. a kind of plant multi-effect compound agent of mosquito-proof sting according to claim 1-3, it is characterised in that：The tea tree
The production method of essential oil is：First tea tree is cleaned, then crushes and is soaked in water 10 minutes, then squeezed out come smart by squeezer
Fluid, then by purification bottling, the Cremophor RH40 is made with same method.
5. a kind of plant multi-effect compound agent of mosquito-proof sting according to claim 1-4, it is characterised in that：The gold and silver
Flower extracting solution production method be：First honeysuckle is cleaned, then crushes and is soaked in water 10 minutes, then squeezed by squeezer
Out liquid, then by purification bottling, the wild chrysanthemum extracting solution, extract solution from aloe and menthol pass through identical side
Method is made.
6. a kind of plant multi-effect compound agent of mosquito-proof sting according to claim 5, it is characterised in that：The menthol
By being extracted in the leaf and stem of peppermint.
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| CN201811057347.4A CN108721478A (en) | 2018-09-11 | 2018-09-11 | A kind of plant multi-effect compound agent of mosquito-proof sting |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110317678A (en) * | 2019-07-22 | 2019-10-11 | 东源县大地农林发展有限公司 | A kind of tea tree ethereal oil extracting method and the skin care item using tea tree ethereal oil preparation |
| CN110917340A (en) * | 2019-12-03 | 2020-03-27 | 云南慎言生物科技有限公司 | Composition for treating dry and itching skin and skin care ointment thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101884608A (en) * | 2010-07-09 | 2010-11-17 | 天津郁美净集团有限公司 | Mosquito repelling composition |
-
2018
- 2018-09-11 CN CN201811057347.4A patent/CN108721478A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101884608A (en) * | 2010-07-09 | 2010-11-17 | 天津郁美净集团有限公司 | Mosquito repelling composition |
Non-Patent Citations (1)
| Title |
|---|
| 3156医药网: "复美之童康肤宝不被蚊虫骚扰", 《HTTP://ZIXUN.3156.CN/U88A215543.SHTML》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110317678A (en) * | 2019-07-22 | 2019-10-11 | 东源县大地农林发展有限公司 | A kind of tea tree ethereal oil extracting method and the skin care item using tea tree ethereal oil preparation |
| CN110917340A (en) * | 2019-12-03 | 2020-03-27 | 云南慎言生物科技有限公司 | Composition for treating dry and itching skin and skin care ointment thereof |
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Application publication date: 20181102 |