CN108720003A - A kind of composition and the preparation method and application thereof with fat-reducing and antihyperglycemic - Google Patents
A kind of composition and the preparation method and application thereof with fat-reducing and antihyperglycemic Download PDFInfo
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- CN108720003A CN108720003A CN201810643459.1A CN201810643459A CN108720003A CN 108720003 A CN108720003 A CN 108720003A CN 201810643459 A CN201810643459 A CN 201810643459A CN 108720003 A CN108720003 A CN 108720003A
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/10—Products from fruits or vegetables; Preparation or treatment thereof of tuberous or like starch containing root crops
- A23L19/115—Konjak; Konntaku
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention belongs to field of health care food, more particularly to a kind of composition with fat-reducing and antihyperglycemic and preparation method and application, the composition includes konjaku, Gynura procumbens (Lour.) Merr and barley seedling, in parts by weight, 0.5-5 parts of konjaku, 0.1-8 parts of Gynura procumbens (Lour.) Merr, 0.05-1.5 parts of barley seedling can be synergistic by compatibility.Clinical trial proves, the composition, which can lose weight, reduce waistline, upper-arm circumference and Tui encloses, compared with knob Lay is good for capsule and green thin balsam pear cellulose soft capsules, weight-reducing, lipid-lowering effect are more notable, and the composition preparation process is simple, production cost is low, solves currently on the market the drawbacks such as weight-reducing and lipid-lowering product effect is undesirable, product cost is high, easy rebound.
Description
Technical field
The invention belongs to field of health care food, and in particular to a kind of composition and its preparation side with fat-reducing and antihyperglycemic
Method.
Background technology
It refers to that body fat cell number increases or volume increases that obesity, which refers to obesity, causes fat accumulation excessive, makes body
20% or more pathological state of the weight that is above standard again.The continuous improvement of living standard, the variation of dietary structure, automobile use
Increase and corresponding movement is reduced so that the problem of obesity of people is increasingly prominent, and obesity continues to increase.Obesity is brought not
Only appearance instrument is affected, and obesity can cause a series of serious complication, such as hypertension, hyperlipidemia, diabetes, hat
Worry, cranial vascular disease, fatty liver, nephrosis, intestinal cancer, gout (hyperuricemia), sex dysfunction are even early death, seriously threaten
People's health.
For problem of obesity, current weight-reducing measure mainly has：Exercise, dietary therapy, operation, oral diet products, cave
Position massage and acupuncture.Although there are many method, takes exercise and dietary therapy needs prodigious willpower, generally is difficult to adhere to；Operation subtracts
Fertilizer will appear wound, and somewhat expensive has certain risk；Point massage and acupuncture generally require the longer course for the treatment of, need specially
People implements, not convenient enough, it is difficult to adhere to.
Oral diet products currently on the market mainly have the function that weight-reducing, but diuretics by diuresis and lead to diarrhea mode
Or lead to diarrhea agent makes body dehydration allow weight loss, but body fat content is not reduced.Also, take such weight-reducing for a long time
Medicine, it is larger to body harm, it is susceptible to the side effects such as gastrointestinal dysfunction, anaemia, malnutrition, kidney function damage.In addition,
Such diet products has rebound phenomena, fat-reducing effect unobvious.Because of effect unobvious, pole existing for existing market diet products
Easily rebound, the shortcomings of product cost is high, side effect is big, be badly in need of developing it is a kind of really effectively, the production of good antiobesity action can be played
Product.
Invention content
In view of this, the present invention provides a kind of composition and the preparation method and application thereof with fat-reducing and antihyperglycemic,
For solving the shortcomings of existing diet products rebound there are effect unobvious, easily, product cost is high, side effect is big, it is difficult to full
The problem of foot vast adiposis patient demand.
The specific technical solution of the present invention is as follows：
A kind of composition with fat-reducing and antihyperglycemic, including：Konjaku, Gynura procumbens (Lour.) Merr and barley seedling；
In parts by weight, konjaku 0.5-5 parts, 0.1-8 parts of Gynura procumbens (Lour.) Merr, 0.05-1.5 parts of barley seedling.
Konjaku contains a large amount of plant cellulose, can promote gastrointestinal peristalsis, relax bowel, and reduces suction of the enteron aisle to fat
It receives, wherein glucomannan water swelling, it is possible to increase have satiety to 80 times or so of original volume, thus after eating, can reduce
Meal size is ideal diet food.
The absorption of barley seedling energy restricted part sugar and fat, and body fat consumption is made to increase, effective obesity controlling, wherein
SOD enzymes make gastrointestinal tract profitable strain mass propagation, and the metabolin volume in enteron aisle is made to increase, is soft, promote intestines peristalsis, improve
The problem of dry and hard excrement, constipation, reduces the absorption of fat.
Contain a large amount of flavones, chlorogenic acid and Thick many candies in Gynura procumbens (Lour.) Merr, internal cholesterol biosynthesis can be reduced, is catalyzed fat
Fat hydrolyzes, and generates aliphatic acid and glycerine, inhibits the activity of lipase, reduces blood lipid level.In addition, the fat that Gynura procumbens (Lour.) Merr contains
Fat acid and water-soluble dietary fiber, can remove internal cholesterol, adjust along stomach, promote the excretion of cholesterol.
In some embodiments, in the composition of the present invention with fat-reducing and antihyperglycemic, in parts by weight, konjaku
1 part, 3.3 parts of Gynura procumbens (Lour.) Merr, 0.1 part of barley seedling.
In some embodiments, in the composition of the present invention with fat-reducing and antihyperglycemic, in parts by weight, konjaku
3.5 parts, 1.5 parts of Gynura procumbens (Lour.) Merr, 0.1 part of barley seedling.
In some embodiments, in the composition of the present invention with fat-reducing and antihyperglycemic, in parts by weight, konjaku
0.75 part, 2 parts of Gynura procumbens (Lour.) Merr, 1 part of barley seedling.
The present invention also provides a kind of health products with fat-reducing and antihyperglycemic, including can be connect on the composition and health products
The auxiliary material received.
The present invention also provides the preparation methods of the composition, include the following steps：
1) konjaku and Gynura procumbens (Lour.) Merr are extracted using ethyl alcohol, concentrates, dries, obtain extract dry powder；
2) barley seedling is dried, crushed, obtain barley seedling dry powder；
3) by the extract dry powder that step 1) obtains and the barley seedling dry powder blend that step 2) obtains, composition is obtained.
Wherein, it is preferred that concentration of alcohol described in step 1) is 20%-90%；The ethyl alcohol be added quality be konjaku and
2-20 times of Gynura procumbens (Lour.) Merr gross mass.
In some embodiments, the concentration of alcohol is 50%.
In some embodiments, the concentration of alcohol is 70%.
Preferably, concentration described in step 1) is that reduced vacuum concentrates, and the drying is spray drying.
Preferably, dry to be freeze-dried described in step 2), described crush is air-flow crushing.
The present invention provides a kind of composition and preparation method with fat-reducing and antihyperglycemic, the composition include evil spirit
Taro, Gynura procumbens (Lour.) Merr and barley seedling, in parts by weight, 0.5-5 parts of konjaku, 0.1-8 parts of Gynura procumbens (Lour.) Merr, barley seedling 0.05-1.5
Part, it can be synergistic by compatibility.Clinical experiments have proved that the composition can lose weight, reduce waistline, upper-arm circumference and Tui
It encloses, compared with knob Lay is good for capsule and green thin balsam pear cellulose soft capsules, weight-reducing, lipid-lowering effect are more notable, and the composition prepares work
Skill is simple, production cost is low, solve currently on the market weight-reducing and lipid-lowering product effect is undesirable, product cost is high, it is easy rebound etc.
Drawback.
Description of the drawings
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below
There is attached drawing needed in technology description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this
The embodiment of invention for those of ordinary skill in the art without creative efforts, can also basis
The attached drawing of offer obtains other attached drawings.
Fig. 1 is the flow chart that the present composition is prepared in embodiment 1.
Specific implementation mode
Embodiment 1
Dry konjaku 300kg, Gynura procumbens (Lour.) Merr 1000kg are taken, is extracted with 50% alcohol reflux, is extracted altogether twice, every time
2-3 hours, merge extracting solution, filtering is concentrated under reduced pressure to obtain liquid extract, carries out being spray-dried to obtain extract dry powder, separately take barley seedling
300kg, by freeze-drying, air-flow crushing is sterilized up to barley seedling dry powder.
Extract dry powder 115kg is taken, with barley seedling dry powder 55kg and starch 50kg, 3% hydroxypropyl methylcellulose is added in mixing
It for adhesive, is stirred after water is added, is pelletized with granulator, whole grain is carried out after dry, cross 60 mesh sieve, remove powder portion
Point, pack up to composition granule, preparation flow such as Fig. 1, wherein " taking powder by force ", which refers to, removes powder part.
Embodiment 2
Take dry konjaku 350kg, Gynura procumbens (Lour.) Merr 150kg, barley seedling 10kg to prepare as described in Example 1 to get
The product of embodiment 2.
Embodiment 3
Dry konjaku 150kg, Gynura procumbens (Lour.) Merr 400kg are taken, is extracted with 70% alcohol reflux, is extracted 2 times altogether, each 2-
3 hours, merges extracting solution, filtering, reduced pressure, carry out being spray-dried to obtain extract dry powder, separately take 200kg barley seedlings, pass through
Freeze-drying, air-flow crushing are sterilized up to barley seedling dry powder.
It is bonding to take 55 kilograms of extract dry powder, barley seedling dry powder 15kg and starch 50kg, 3% hydroxypropyl methylcellulose of addition
Agent mixes, and granulation carries out whole grain after dry, crosses 60 mesh sieve, is packed, 12 grams every bag.
Embodiment 4
Composition, knob Lay described in embodiment 1-3 are good for capsule and green thin balsam pear cellulose soft capsules using effect comparison.
The composition dose：Every bag of 12g, it is 2-3 times daily, one bag every time；The composition instructions of taking：40-60
DEG C warm boiled water.Niu Lai is good for capsule and green thin balsam pear cellulose soft capsules dose and the requirement of instructions of taking by specification.
250 volunteers are randomly selected, age 25-50 Sui is all overweight obese patient.Three groups are randomly divided into, often
50 people of group take composition, knob Lay described in embodiment 1-3 and are good for capsule and green thin balsam pear cellulose soft capsules two months, comparing bulk respectively
Weight, waistline, upper-arm circumference and Tui enclose decline situation, and as a result such as table 1, the volunteer's obesity for taking composition described in embodiment 1-3 is big
Part significantly slows, and has 82% obesity of volunteer to significantly slow wherein taking composition described in embodiment 3, and right
The product effect in market is then far away from the composition in ratio.
1 composition of table, knob Lay are good for the use result of capsule and green thin balsam pear cellulose soft capsules
Embodiment 5
Konjaku, the extract of Gynura procumbens (Lour.) Merr and the dry powder of barley seedling are prepared respectively according to the method for embodiment 1, with implementation
Example 3 is compared, and the active ingredient in embodiment 3 is 7 grams every bag.
150 volunteers are randomly selected, age 25-50 Sui is all overweight obese patient.Three groups are randomly divided into, often
50 people of group take barley seedling dry powder, Rhizoma amorphophalli extract and lie down chrysanthemum Notogineng Extract two months, it is solid to compare weight, total courage respectively
Alcohol and triglycerides decline situation, compared with composition effect described in embodiment 3, as a result such as table 2.
2 single component of table is counted with composition service condition
It is significantly slowed the results show that taking single component volunteer's obesity part, and takes and combined described in embodiment 3
Object has the obesity of 82% volunteer to significantly slow, and shows the effect for taking single component far away from the composition.
The above is only a preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, various improvements and modifications may be made without departing from the principle of the present invention, these improvements and modifications are also answered
It is considered as protection scope of the present invention.
Claims (9)
1. a kind of composition with fat-reducing and antihyperglycemic, which is characterized in that including：Konjaku, Gynura procumbens (Lour.) Merr and barley seedling；
In parts by weight, konjaku 0.5-5 parts, 0.1-8 parts of Gynura procumbens (Lour.) Merr, 0.05-1.5 parts of barley seedling.
2. composition according to claim 1, which is characterized in that in parts by weight, 1 part of konjaku, Gynura procumbens (Lour.) Merr 3.3
Part, 0.1 part of barley seedling.
3. composition according to claim 1, which is characterized in that in parts by weight, 3.5 parts of konjaku, Gynura procumbens (Lour.) Merr 1.5
Part, 0.1 part of barley seedling.
4. composition according to claim 1, which is characterized in that in parts by weight, 0.75 part of konjaku, Gynura procumbens (Lour.) Merr 2
Part, 1 part of barley seedling.
5. a kind of health products with fat-reducing and antihyperglycemic, which is characterized in that including being combined described in claim 1-4 any one
Acceptable auxiliary material on object and health products.
6. the preparation method of composition described in claim 1, includes the following steps：
1) konjaku and Gynura procumbens (Lour.) Merr are extracted using ethyl alcohol, concentrates, dries, obtain extract dry powder；
2) barley seedling is dried, crushed, obtain barley seedling dry powder；
3) by the extract dry powder that step 1) obtains and the barley seedling dry powder blend that step 2) obtains, composition is obtained.
7. preparation method according to claim 6, which is characterized in that concentration of alcohol described in step 1) is 20%-90%；
2-20 times that quality is konjaku and Gynura procumbens (Lour.) Merr gross mass is added in the ethyl alcohol.
8. preparation method according to claim 6, which is characterized in that concentration described in step 1) is that reduced vacuum concentrates；
The drying is spray drying.
9. preparation method according to claim 6, which is characterized in that dry for freeze-drying described in step 2)；It is described
It is air-flow crushing to crush.
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| KR20120022085A (en) * | 2010-08-25 | 2012-03-12 | 주식회사 인섹트 바이오텍 | Formulations for prevention or treatment of obesity, hyperlipidemia, atherosclerosis, fatty liver, diabetes mellitus or metabolic syndrome comprising extracts of glycine max leaves as an active ingredient |
| CN103519311A (en) * | 2013-10-18 | 2014-01-22 | 章嘉泽 | Barley seedling clear juice solid beverage and preparation method thereof |
| CN104171188A (en) * | 2014-08-04 | 2014-12-03 | 廖为明 | Gynura procumbens health tea |
| CN106924318A (en) * | 2015-12-30 | 2017-07-07 | 北京万源普达医疗科技有限公司 | A kind of new application of Gynura procumbens (Lour.) Merr or its extract |
| CN107853549A (en) * | 2017-11-14 | 2018-03-30 | 安徽华健生物科技有限公司 | A kind of processing method of barley young leaf konjaku coixlacrymajobi powder |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| KR20120022085A (en) * | 2010-08-25 | 2012-03-12 | 주식회사 인섹트 바이오텍 | Formulations for prevention or treatment of obesity, hyperlipidemia, atherosclerosis, fatty liver, diabetes mellitus or metabolic syndrome comprising extracts of glycine max leaves as an active ingredient |
| CN103519311A (en) * | 2013-10-18 | 2014-01-22 | 章嘉泽 | Barley seedling clear juice solid beverage and preparation method thereof |
| CN104171188A (en) * | 2014-08-04 | 2014-12-03 | 廖为明 | Gynura procumbens health tea |
| CN106924318A (en) * | 2015-12-30 | 2017-07-07 | 北京万源普达医疗科技有限公司 | A kind of new application of Gynura procumbens (Lour.) Merr or its extract |
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