CN108699556B - 使用靶向myd88或tlr3的rna复合物治疗老年性黄斑变性 - Google Patents

使用靶向myd88或tlr3的rna复合物治疗老年性黄斑变性 Download PDF

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CN108699556B
CN108699556B CN201680078793.6A CN201680078793A CN108699556B CN 108699556 B CN108699556 B CN 108699556B CN 201680078793 A CN201680078793 A CN 201680078793A CN 108699556 B CN108699556 B CN 108699556B
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rna complex
rna
asirna
sense strand
myd88
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CN108699556A (zh
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D·K·李
S·W·弘
I·弘
J·H·黄
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Olix Pharmaceuticals Inc
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CN201680078793.6A 2015-11-16 2016-11-15 使用靶向myd88或tlr3的rna复合物治疗老年性黄斑变性 Active CN108699556B (zh)

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US201562255878P 2015-11-16 2015-11-16
US62/255,878 2015-11-16
PCT/IB2016/001745 WO2017085550A1 (en) 2015-11-16 2016-11-15 Treatment of age-related macular degeneration using rna complexes that target myd88 or tlr3

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CN108699556B true CN108699556B (zh) 2023-02-17

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EP (2) EP4454637A3 (enExample)
JP (1) JP7027311B2 (enExample)
KR (1) KR102727666B1 (enExample)
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Families Citing this family (10)

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ES2930555T3 (es) 2010-10-22 2022-12-16 Olix Pharmaceuticals Inc Moléculas de ácido nucleico que inducen la interferencia de ARN y usos de las mismas
EP3514236A1 (en) 2012-05-22 2019-07-24 Olix Pharmaceuticals, Inc. Rna-interference-inducing nucleic acid molecule able to penetrate into cells, and use therefor
CN108699556B (zh) 2015-11-16 2023-02-17 奥利克斯医药有限公司 使用靶向myd88或tlr3的rna复合物治疗老年性黄斑变性
CN108779464B (zh) 2016-02-02 2022-05-17 奥利克斯医药有限公司 使用靶向angpt2和pdgfb的rna复合物治疗血管生成相关性疾病
KR102825946B1 (ko) 2016-02-02 2025-06-27 올릭스 주식회사 IL4Rα, TRPA1, 또는 F2RL1을 표적화하는 RNA 복합체를 사용한 아토피 피부염 및 천식의 치료
US10301628B2 (en) 2016-04-11 2019-05-28 Olix Pharmaceuticals, Inc. Treatment of idiopathic pulmonary fibrosis using RNA complexes that target connective tissue growth factor
KR101916652B1 (ko) 2016-06-29 2018-11-08 올릭스 주식회사 작은 간섭 rna의 rna 간섭효과 증진용 화합물 및 이의 용도
KR20190108167A (ko) 2017-02-10 2019-09-23 성균관대학교산학협력단 Rna 간섭을 위한 긴 이중가닥 rna
KR102421750B1 (ko) * 2020-05-26 2022-07-19 올릭스 주식회사 MyD88을 표적으로 하는 RNAi 제제 및 이의 용도
KR20240169190A (ko) * 2023-05-23 2024-12-03 주식회사 에스앤케이테라퓨틱스 자가면역 질환 치료를 위한 신규 MyD88 억제제 및 이의 용도

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