CN108697782A - 针对pcv2病毒和猪肺炎支原体感染的组合疫苗 - Google Patents

针对pcv2病毒和猪肺炎支原体感染的组合疫苗 Download PDF

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Publication number
CN108697782A
CN108697782A CN201780014561.9A CN201780014561A CN108697782A CN 108697782 A CN108697782 A CN 108697782A CN 201780014561 A CN201780014561 A CN 201780014561A CN 108697782 A CN108697782 A CN 108697782A
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CN
China
Prior art keywords
vaccine
pcv2
immunogene
mycoplasma hyopneumoniae
replicating
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Pending
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CN201780014561.9A
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English (en)
Chinese (zh)
Inventor
M.斯诺
M.H.维特弗利耶
V.法辛格尔
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Intervet International BV
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Intervet International BV
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Publication of CN108697782A publication Critical patent/CN108697782A/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0241Mollicutes, e.g. Mycoplasma, Erysipelothrix
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/105Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/10011Circoviridae
    • C12N2750/10034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
CN201780014561.9A 2016-03-23 2017-03-22 针对pcv2病毒和猪肺炎支原体感染的组合疫苗 Pending CN108697782A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16161997 2016-03-23
EP16161997.8 2016-03-23
PCT/EP2017/056831 WO2017162741A1 (en) 2016-03-23 2017-03-22 A combination vaccine against pcv2 virus and mycoplasma hyopneumoniae infection

Publications (1)

Publication Number Publication Date
CN108697782A true CN108697782A (zh) 2018-10-23

Family

ID=55589754

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201780014561.9A Pending CN108697782A (zh) 2016-03-23 2017-03-22 针对pcv2病毒和猪肺炎支原体感染的组合疫苗

Country Status (7)

Country Link
US (1) US20190105385A1 (https=)
EP (1) EP3432919A1 (https=)
JP (1) JP6907227B2 (https=)
CN (1) CN108697782A (https=)
BR (1) BR112018069100A2 (https=)
RU (1) RU2018137034A (https=)
WO (1) WO2017162741A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114364398A (zh) * 2019-09-12 2022-04-15 英特维特国际股份有限公司 用于皮内施用的联合疫苗
CN115887636A (zh) * 2022-01-18 2023-04-04 武汉科前生物股份有限公司 猪圆环病毒2型、猪肺炎支原体、猪链球菌三联灭活疫苗及其制备方法

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112020011044A2 (pt) * 2017-12-04 2020-11-17 Intervet International B.V. vacinação com partículas de replicon e adjuvante de óleo
JP7510874B2 (ja) * 2017-12-22 2024-07-04 ヒプラ シエンティフィック エセ.エレ.ウ. マイコプラズマ及びブタサーコウイルスに対する皮内混合ワクチン
KR20230004654A (ko) * 2020-04-20 2023-01-06 인터벳 인터내셔널 비.브이. 마이코플라즈마 하이오뉴모니아에로부터 방어하기 위한 백신
CA3176154A1 (en) 2020-04-20 2021-10-28 Maarten Hendrik Witvliet A combination of vaccines to prophylactically treat a pig
WO2025132513A1 (en) 2023-12-19 2025-06-26 Intervet International B.V. Low-energy electron irradiation-inactivated mollicutes

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US20050220814A1 (en) * 2004-04-05 2005-10-06 Dominowski Paul J Microfluidized oil-in-water emulsions and vaccine compositions
WO2007006939A2 (fr) * 2005-07-07 2007-01-18 Sanofi Pasteur Emulsion immuno-adjuvante thermoreversible
CN102006884A (zh) * 2008-04-18 2011-04-06 英特威国际有限公司 防御胞内劳森菌、猪肺炎支原体和猪圆环病毒的疫苗
CN103263666A (zh) * 2013-05-24 2013-08-28 北京大北农科技集团股份有限公司动物医学研究中心 猪圆环病毒2型、猪支原体肺炎二联灭活疫苗及其制备方法
CN104043118A (zh) * 2013-03-11 2014-09-17 普莱柯生物工程股份有限公司 猪prrsv、猪肺炎支原体和pvc-2抗原在制备疫苗中的应用
CN104271153A (zh) * 2012-04-04 2015-01-07 硕腾有限责任公司 Pcv/猪肺炎支原体/prrs组合疫苗
CN104334186A (zh) * 2012-04-04 2015-02-04 硕腾有限责任公司 Pcv/猪肺炎支原体组合疫苗

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HU212924B (en) * 1989-05-25 1996-12-30 Chiron Corp Adjuvant formulation comprising a submicron oil droplet emulsion
SI1651265T1 (sl) * 2003-07-24 2008-10-31 Merial Ltd Formulacije cepiva, ki obsegajo emulzijo olje v vodi
RU2007130801A (ru) 2005-01-13 2009-02-20 Берингер Ингельхайм Ветмедика Гмбх (De) Улучшенные вакцины против репродуктивно-респираторного синдрома свиней (prrs)
US8834891B2 (en) * 2005-03-14 2014-09-16 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions comprising Lawsonia intracellularis
ES2425228T3 (es) 2005-09-09 2013-10-14 Intervet International B.V. Vacuna contra el PCV-2
DK3766518T3 (da) 2005-12-29 2026-04-13 Boehringer Ingelheim Animal Health Usa Inc Immunogen pcv2-sammensætning til mindskelse af kliniske symptomer hos grise
PT2094872T (pt) 2006-12-15 2017-04-27 Boehringer Ingelheim Vetmedica Inc Tratamento de porcos seropositivos para o anticorpo anti-pcv2 com antigénio de pcv2
US8728487B2 (en) 2011-01-20 2014-05-20 Hua Wu Attenuated live vaccine for prevention of porcine reproductive and respiratory syndrome
JP6460792B2 (ja) * 2011-09-09 2019-01-30 ナノバイオ コーポレーション ナノエマルション呼吸器合胞体ウイルス(rsv)サブユニットワクチン
US9457073B2 (en) 2012-09-26 2016-10-04 University Of Manitoba Live attenuated replication-competent arteriviruses having decreased dub/deisgylating activity
KR102547168B1 (ko) * 2013-12-03 2023-06-22 인터벳 인터내셔널 비.브이. 로소니아 인트라셀룰라리스 및 돼지 써코바이러스 2에 대한 백신

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050220814A1 (en) * 2004-04-05 2005-10-06 Dominowski Paul J Microfluidized oil-in-water emulsions and vaccine compositions
CN1997390A (zh) * 2004-04-05 2007-07-11 辉瑞产品有限公司 微流化水包油乳状液和疫苗组合物
WO2007006939A2 (fr) * 2005-07-07 2007-01-18 Sanofi Pasteur Emulsion immuno-adjuvante thermoreversible
CN102006884A (zh) * 2008-04-18 2011-04-06 英特威国际有限公司 防御胞内劳森菌、猪肺炎支原体和猪圆环病毒的疫苗
CN104271153A (zh) * 2012-04-04 2015-01-07 硕腾有限责任公司 Pcv/猪肺炎支原体/prrs组合疫苗
CN104334186A (zh) * 2012-04-04 2015-02-04 硕腾有限责任公司 Pcv/猪肺炎支原体组合疫苗
JP2015512450A (ja) * 2012-04-04 2015-04-27 ゾエティス・エルエルシー Pcv/マイコプラズマ・ハイオニューモニエ/prrs混合ワクチン
CN104043118A (zh) * 2013-03-11 2014-09-17 普莱柯生物工程股份有限公司 猪prrsv、猪肺炎支原体和pvc-2抗原在制备疫苗中的应用
CN103263666A (zh) * 2013-05-24 2013-08-28 北京大北农科技集团股份有限公司动物医学研究中心 猪圆环病毒2型、猪支原体肺炎二联灭活疫苗及其制备方法

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114364398A (zh) * 2019-09-12 2022-04-15 英特维特国际股份有限公司 用于皮内施用的联合疫苗
CN115887636A (zh) * 2022-01-18 2023-04-04 武汉科前生物股份有限公司 猪圆环病毒2型、猪肺炎支原体、猪链球菌三联灭活疫苗及其制备方法

Also Published As

Publication number Publication date
JP2019509300A (ja) 2019-04-04
RU2018137034A3 (https=) 2020-06-26
EP3432919A1 (en) 2019-01-30
BR112018069100A2 (pt) 2019-01-29
WO2017162741A1 (en) 2017-09-28
JP6907227B2 (ja) 2021-07-21
RU2018137034A (ru) 2020-04-23
US20190105385A1 (en) 2019-04-11

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