CN108697096B - 对icam-1特异性的i结构域嵌合抗原受体 - Google Patents

对icam-1特异性的i结构域嵌合抗原受体 Download PDF

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CN108697096B
CN108697096B CN201780004619.1A CN201780004619A CN108697096B CN 108697096 B CN108697096 B CN 108697096B CN 201780004619 A CN201780004619 A CN 201780004619A CN 108697096 B CN108697096 B CN 108697096B
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CN108697096A (zh
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金文殊
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Cornell University
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CN201780004619.1A 2016-09-02 2017-08-11 对icam-1特异性的i结构域嵌合抗原受体 Active CN108697096B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662383139P 2016-09-02 2016-09-02
US62/383,139 2016-09-02
US201662419817P 2016-11-09 2016-11-09
US62/419,817 2016-11-09
PCT/US2017/046630 WO2018052594A1 (en) 2016-09-02 2017-08-11 I domain chimeric antigen receptor specific to icam-1

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CN108697096A CN108697096A (zh) 2018-10-23
CN108697096B true CN108697096B (zh) 2022-05-03

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US (6) US10577408B2 (https=)
EP (1) EP3522718B1 (https=)
JP (1) JP6996772B2 (https=)
KR (1) KR102613109B1 (https=)
CN (1) CN108697096B (https=)
AU (1) AU2017325678B2 (https=)
CA (1) CA3033846C (https=)
ES (1) ES2971550T3 (https=)
SG (1) SG11201901505SA (https=)
WO (2) WO2018044534A1 (https=)

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ES2971550T3 (es) * 2016-09-02 2024-06-05 Univ Cornell Receptor de antígeno quimérico de dominio I específico para ICAM-1
CA3050085A1 (en) 2017-01-20 2018-07-26 Juno Therapeutics Gmbh Cell surface conjugates and related cell compositions and methods
MX2019012017A (es) * 2017-04-07 2020-02-12 Juno Therapeutics Inc Celulas modificadas que expresan antigeno de membrana especifico de prostata (psma) o una forma modificada del mismo y metodos relacionados.
US11866494B2 (en) * 2018-08-31 2024-01-09 Innovative Cellular Therapeutics Holdings, Ltd. CAR T therapy through uses of co-stimulation
WO2022126084A1 (en) * 2020-12-09 2022-06-16 Affyimmune Therapeutics, Inc. Dual chimeric antigen receptor targeting epcam and icam-1
CN118146395A (zh) * 2021-02-08 2024-06-07 浙江大学 一种以内源性蛋白质分子替代单结构域抗体的嵌合抗原受体
CN120187461A (zh) * 2022-09-14 2025-06-20 生物权威(澳大利亚)有限责任公司 免疫细胞的体内检测
US12385818B2 (en) 2023-02-14 2025-08-12 Saudi Arabian Oil Company Modeling gas desorption in a subsurface reservoir
EP4687959A1 (en) 2023-03-24 2026-02-11 Cornell University Utilizing t cells derived from tumor draining lymph nodes for chimeric antigen receptor (car) t cell therapy for the treatment of cancer
US20250288611A1 (en) * 2024-03-04 2025-09-18 AffyImmune Therapeutics Inc. Icam-1 targeted car constructs and methods of treatment

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US20180066035A1 (en) 2018-03-08
US20230265165A1 (en) 2023-08-24
JP2019530441A (ja) 2019-10-24
US12410235B2 (en) 2025-09-09
US20210309721A1 (en) 2021-10-07
US20200017573A1 (en) 2020-01-16
CA3033846C (en) 2025-03-11
KR102613109B1 (ko) 2023-12-13
US12325736B2 (en) 2025-06-10
US10428136B2 (en) 2019-10-01
ES2971550T3 (es) 2024-06-05
AU2017325678B2 (en) 2022-03-17
AU2017325678A1 (en) 2019-03-14
WO2018052594A1 (en) 2018-03-22
US20200181238A1 (en) 2020-06-11
JP6996772B2 (ja) 2022-02-21
SG11201901505SA (en) 2019-03-28
WO2018044534A1 (en) 2018-03-08
KR20190057072A (ko) 2019-05-27
US11634471B2 (en) 2023-04-25
EP3522718A1 (en) 2019-08-14
EP3522718A4 (en) 2020-02-19
EP3522718B1 (en) 2023-07-05
CN108697096A (zh) 2018-10-23
US10577408B2 (en) 2020-03-03
US11046748B2 (en) 2021-06-29
US20180066037A1 (en) 2018-03-08
CA3033846A1 (en) 2018-03-22

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