CN108685730A - It is a kind of that there is antioxygen, reparation, crease-resistant, water supplement function solution and preparation method thereof - Google Patents

It is a kind of that there is antioxygen, reparation, crease-resistant, water supplement function solution and preparation method thereof Download PDF

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Publication number
CN108685730A
CN108685730A CN201810748707.9A CN201810748707A CN108685730A CN 108685730 A CN108685730 A CN 108685730A CN 201810748707 A CN201810748707 A CN 201810748707A CN 108685730 A CN108685730 A CN 108685730A
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CN
China
Prior art keywords
solution
water
skin
acid sodium
reparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810748707.9A
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Chinese (zh)
Inventor
焦华
周建娜
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tianjin Ruanyin Technology Co Ltd
Original Assignee
Tianjin Ruanyin Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tianjin Ruanyin Technology Co Ltd filed Critical Tianjin Ruanyin Technology Co Ltd
Priority to CN201810748707.9A priority Critical patent/CN108685730A/en
Publication of CN108685730A publication Critical patent/CN108685730A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/88Polyamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

Abstract

There is antioxygen, reparation, crease-resistant, water supplement function solution and preparation method thereof the present invention relates to a kind of, this solution is made of hydrolysis Sodium Hyaluronate, polyglutamic acid sodium, Phenoxyethanol, water.Each ingredient collaboration enhancing, realizes long-acting moisturizing, inhibits hyaluronidase activity, generate natural moisturizing factor between solution provided by the invention, skin bullet is kept, is mildly inhibited tyrosinase activity, melanin is inhibited to generate, anti-oxidant and pigmentation, deep moisturizing, light sensation whitening.The skin sense of this solution is smooth but not greasy.

Description

It is a kind of that there is antioxygen, reparation, crease-resistant, water supplement function solution and preparation method thereof
Technical field
The invention belongs to cosmetic technical fields, and in particular to a kind of to have antioxygen, reparation, crease-resistant, water supplement function molten Liquid and preparation method thereof.
Background technology
Environmental factor, naturally-aged, skin disease are that dim mute, the coarse, cutis laxa of the colour of skin, wrinkle is caused to increase, do not have The principal element of the skins such as elasticity disorder.It is the effective of the above skin problem of solution by antioxygen, reparation, crease-resistant, moisturizing Approach.
Aqueous solution, be a kind of low viscosity, good fluidity liquid skin protection cosmetics, can be that skin supplements water rapidly Point, realize antioxygen, reparation, crease-resistant, water supplement function.Aqueous solution ingredient is various at present, and interaction mechanism is not between chemical composition Enough clear, at the same time allergic phenomena is relatively common.With the continuous improvement that people require cosmetics, natural, safety, green Cosmetics just receiving consumer and pursuing.Therefore it is simple at being grouped as that the present invention provides a kind of, function significantly, natural, safety, The product of health.
Invention content
There is antioxygen, reparation, crease-resistant, water supplement function solution and its preparation side the purpose of the present invention is to provide a kind of Method.
In order to achieve the above objectives, the technical solution adopted by the present invention is as follows:
It is a kind of that have antioxygen, reparation, crease-resistant, water supplement function solution include following components:Hydrolyze Sodium Hyaluronate, polyglutamic Sour sodium, Phenoxyethanol, water.
Preferably, each weight percent of solution each component is as follows:Hydrolyze Sodium Hyaluronate 1% ± 0.2%, polyglutamic acid Sodium 0.25% ± 0.05%, Phenoxyethanol 0.4% ± 0.1%, surplus are deionized water.
Preferably, the hydrolysis Sodium Hyaluronate molecular weight is between 3000-400000Da;Polyglutamic acid sodium molecule amount exists Between 3000000-9000000Da.
Hydrolysis Sodium Hyaluronate of the molecular weight between 3000-400000Da can realize that Transdermal absorption, nourishing are repaiied respectively It answers skin surface and forms the triple functions of ventilative netted hydration shell in skin surface.Making skin, water profit is soft from inside to outside, Perfection is bursted forth water light skin.
Polyglutamic acid sodium of the molecular weight between 3000000-9000000Da has excellent biocompatibility, can not only It is effectively isolated, is maintained the ph environment of skin health, and natural moisture preserving ingredient in skin can be promoted to accumulate, promotes natural moisture preserving Factor content.
The activity that hyaluronidase can effectively be inhibited is conducive to the content for maintaining skin hyaluronic acid, promotes skin health, Improve skin quality.
Self dampening system of remodeling skin, further promotes the water holding and moisture-retaining capacity of skin.At the same time it can also permeate Cuticula is impregnated, skin is made smoothly to moisten.
Energy effective activation cell, promotes dermal fibroblasts to synthesize collagen, to improve skin elasticity and softness Degree desalinates microgroove, delaying skin aging.
The activity for effectively inhibiting tyrosinase, reduces the formation of melanin, skin whitening, even skin tone.
Hydrolysis Sodium Hyaluronate of the molecular weight between 3000-400000Da is with molecular weight in 3000000-9000000Da Between polyglutamic acid sodium share and can also build embedding slow-releasing system, promote effectively to absorb, utilize;It is extraneous that skin reply can also be enhanced The resistance of stimulation slows down allergy and inflammatory reaction.
The present invention's further an object is that provide a kind of preparation method of above-mentioned solution, steps are as follows:
A will hydrolyze Sodium Hyaluronate, polyglutamic acid sodium water sequentially adds in container, stir;
Phenoxyethanol is added in container A B, continues to discharge after stirring evenly.
The present invention's further an object is that a kind of application of the above-mentioned solution of offer in cosmetics, the cosmetics include Mildy wash, toner, facial mask, frost, spray.
Table 1:Skin model tests Transdermal absorption
Table 2:The reparation damaged cell function of the present invention
Table 3:The moisture-keeping functions of the present invention
Table 4:Single-wide molecular weight and present invention water conservation data
Table 5:Effect of the present invention to increase skin elasticity
Table 6:Effect of the present invention to increase skin barrier function
Table 7:Desalinate the effect of microgroove
Description of the drawings:
Description of the drawings:
Fig. 1 is the block diagram that the present invention tests transdermal absorption factor by skin model
Fig. 2 is the block diagram that the present invention repairs damaged cell function
Fig. 3 is the moisture-keeping functions comparison block diagram of the present invention and reference substance
Fig. 4 is single-wide molecular weight and present invention water conservation data line chart
Fig. 5 is comparison block diagram of the present invention with reference substance to increase skin elasticity index
Fig. 6 is the increase skin barrier function comparison block diagram of the present invention and reference substance
Fig. 7 is the block diagram of the present invention and reference substance to desalination microgroove effect contrast
Fig. 8 is this solution producing process flow chart
Specific embodiment:
To keep the objectives, technical solutions, and advantages of the present invention easy-to-understand, with reference to embodiments, the present invention is carried out further Explanation.
Embodiment 1
Formula:
Hydrolyze Sodium Hyaluronate 1g polyglutamic acid sodium 0.25g Phenoxyethanol 0.4g water 98.35g.
Preparation method:
A will hydrolyze Sodium Hyaluronate, polyglutamic acid sodium water sequentially adds in container, stir;
Phenoxyethanol is added in container A B, continues to discharge after stirring evenly;
This solution is added in mildy wash according to 10% ratio up to mildy wash C.
Embodiment 2
Formula:
Hydrolyze Sodium Hyaluronate 1g polyglutamic acid sodium 0.25g Phenoxyethanol 0.4g water 98.35g.
Preparation method:
A will hydrolyze Sodium Hyaluronate, polyglutamic acid sodium water sequentially adds in container, stir;
Phenoxyethanol is added in container A B, continues to discharge after stirring evenly;
C is filling by this solution, and packaging gets product toner.
Embodiment 3
Formula:
Hydrolyze Sodium Hyaluronate 1g polyglutamic acid sodium 0.25g Phenoxyethanol 0.4g water 98.35g.
Preparation method:
A will hydrolyze Sodium Hyaluronate, polyglutamic acid sodium water sequentially adds in container, stir;
Phenoxyethanol is added in container A B, continues to discharge after stirring evenly;
Face paper is put this solution and impregnated by C, packs up to facial mask.
Embodiment 4
Formula:
Hydrolyze Sodium Hyaluronate 1g polyglutamic acid sodium 0.25g Phenoxyethanol 0.4g water 98.35g.
Preparation method:
A will hydrolyze Sodium Hyaluronate, polyglutamic acid sodium water sequentially adds in container, stir;
Phenoxyethanol is added in container A B, continues to discharge after stirring evenly;
C by this solution it is filling in pressure vessel up to spray.

Claims (4)

1. a kind of having antioxygen, reparation, crease-resistant, water supplement function solution, it is characterised in that including following components:Hydrolyze hyalomitome Sour sodium, polyglutamic acid sodium, Phenoxyethanol, water.
2. solution according to claim 1, it is characterised in that include the component of following weight percent:Hydrolyze hyaluronic acid Sodium 1% ± 0.2%, polyglutamic acid sodium 0.25% ± 0.05%, Phenoxyethanol 0.4% ± 0.1%, surplus are deionized water.
3. solution according to claim 1, it is characterised in that hydrolysis Sodium Hyaluronate molecular weight 3000-400000Da it Between, polyglutamic acid sodium molecule amount is between 3000000-9000000Da.
4. solution according to claim 1 is applied in cosmetics, the cosmetics include mildy wash, toner, essence Liquid, facial mask, frost, spray, color make-up.
CN201810748707.9A 2018-07-10 2018-07-10 It is a kind of that there is antioxygen, reparation, crease-resistant, water supplement function solution and preparation method thereof Pending CN108685730A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810748707.9A CN108685730A (en) 2018-07-10 2018-07-10 It is a kind of that there is antioxygen, reparation, crease-resistant, water supplement function solution and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810748707.9A CN108685730A (en) 2018-07-10 2018-07-10 It is a kind of that there is antioxygen, reparation, crease-resistant, water supplement function solution and preparation method thereof

Publications (1)

Publication Number Publication Date
CN108685730A true CN108685730A (en) 2018-10-23

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112294706A (en) * 2019-07-31 2021-02-02 太和康美(北京)中医研究院有限公司 Moisturizing composition and preparation method and application thereof

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CN101304724A (en) * 2005-10-20 2008-11-12 生物领先公司 Hyaluronidase inhibitor containing poly-gamma-glutamic acid as an effective component
CN103800219A (en) * 2012-11-08 2014-05-21 山东福瑞达生物科技有限公司 Multifunctional high-efficiency moisturizing stock solution
CN105616293A (en) * 2016-02-04 2016-06-01 陕西艾美雅生物科技有限公司 Skin brightening toner and cosmetic product containing same and usage thereof
CN106074315A (en) * 2016-08-24 2016-11-09 广东芭薇生物科技股份有限公司 A kind of facial mask liquid with multiple skin-care effect and preparation method thereof
CN107693381A (en) * 2017-09-28 2018-02-16 诺斯贝尔化妆品股份有限公司 A kind of bar cloth veneer film containing flexible nano-liposomes
CN107823095A (en) * 2017-12-07 2018-03-23 安徽生物肽产业研究院有限公司 A kind of active peptide facial mask
KR20180060537A (en) * 2016-11-29 2018-06-07 (주)웰빙해피팜 Whitening functional cosmetic composition having skin-regeneration and moistureizing

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101304724A (en) * 2005-10-20 2008-11-12 生物领先公司 Hyaluronidase inhibitor containing poly-gamma-glutamic acid as an effective component
CN103800219A (en) * 2012-11-08 2014-05-21 山东福瑞达生物科技有限公司 Multifunctional high-efficiency moisturizing stock solution
CN105616293A (en) * 2016-02-04 2016-06-01 陕西艾美雅生物科技有限公司 Skin brightening toner and cosmetic product containing same and usage thereof
CN106074315A (en) * 2016-08-24 2016-11-09 广东芭薇生物科技股份有限公司 A kind of facial mask liquid with multiple skin-care effect and preparation method thereof
KR20180060537A (en) * 2016-11-29 2018-06-07 (주)웰빙해피팜 Whitening functional cosmetic composition having skin-regeneration and moistureizing
CN107693381A (en) * 2017-09-28 2018-02-16 诺斯贝尔化妆品股份有限公司 A kind of bar cloth veneer film containing flexible nano-liposomes
CN107823095A (en) * 2017-12-07 2018-03-23 安徽生物肽产业研究院有限公司 A kind of active peptide facial mask

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112294706A (en) * 2019-07-31 2021-02-02 太和康美(北京)中医研究院有限公司 Moisturizing composition and preparation method and application thereof
CN112294706B (en) * 2019-07-31 2022-07-29 太和康美(北京)中医研究院有限公司 Moisturizing composition and preparation method and application thereof

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