CN109730953A - A kind of hyaluronic acid (sodium hyaluronate) stoste and preparation method thereof - Google Patents
A kind of hyaluronic acid (sodium hyaluronate) stoste and preparation method thereof Download PDFInfo
- Publication number
- CN109730953A CN109730953A CN201910044762.4A CN201910044762A CN109730953A CN 109730953 A CN109730953 A CN 109730953A CN 201910044762 A CN201910044762 A CN 201910044762A CN 109730953 A CN109730953 A CN 109730953A
- Authority
- CN
- China
- Prior art keywords
- hyaluronic acid
- sodium hyaluronate
- skin
- stoste
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Cosmetics (AREA)
Abstract
The present invention relates to cosmetic technical fields, specifically a kind of hyaluronic acid (sodium hyaluronate) stoste and preparation method thereof, is made by the component of following quality proportionings: Acritamer 940, QO-100 hydroxyethyl cellulose, hyaluronic acid, Sodium Hyaluronate, hydrolysis hyaluronic acid etc.；The two of task of the present invention are to provide a kind of preparation method of hyaluronic acid (sodium hyaluronate) stoste.
Description
Technical field
The present invention relates to cosmetic technical field, specifically a kind of hyaluronic acid (sodium hyaluronate) stoste and preparation method thereof.
Background technique
With the quickening pace of modern life, night life it is abundant, it is long-term to stay up late and the radiation let us of electronic product
Skin be in a high-risk state, there is drying in the skin of many people, and dark and gloomy, jaundice, lacklustre state will lead to one
A makeup is not docile, decortication, in addition the reason of season, it may appear that the phenomenon that an allergy, this is the prolonged water shortage institute of skin
It is caused.It disappears with age, the ability for making skin lose water storage gradually becomes obscure, aging, and is formed tiny
Wrinkle.Common stoste enhancing skin cell metabolic capabilities are insufficient, can not repair skin and increase elasticity of skin and highlight
The colour of skin, and most of common stoste is added with and works as preservative to the prejudicial substance of skin, damages skin.
Summary of the invention
In order to overcome the above the deficiencies in the prior art, one of task of the invention is to provide a kind of hyaluronic acid (sodium hyaluronate)
Stoste, a kind of hyaluronic acid (sodium hyaluronate) the stoste product can play better moisturizing repair, make up existing stoste
Deficiency removes and contains outside this important performance, can be with anti-wrinkle, whitening, skin lightening；The two of task of the present invention are to provide a kind of transparent
The preparation method of matter acid (sodium hyaluronate) stoste.
One of task of the present invention is achieved through the following technical solutions:
A kind of hyaluronic acid (sodium hyaluronate) stoste, is made by the component of following quality proportionings:
Acritamer 940: 0.08-0.12%；
QO-100 hydroxyethyl cellulose: 0.09-0.12%；
Hyaluronic acid: 0.2-0.5%；
Sodium Hyaluronate: 0.2-0.5%；
Hydrolyze hyaluronic acid: 0.2-0.5%；
Acetylation Sodium Hyaluronate: 0.2-0.5%；
Dipropylene glycol: 3.8-4.2%；
Propylene glycol: 1.8-2.1%；
Glycerol: 1.8-2.2%；
Aloe barbadensis Miller (ALOE BARBADENSIS) leaf extract: 1-2%；
Allantoin: 0.5-0.8%；
GC-04 (decoyl hydroximic acid/glycerol caprylate/parahydroxyacet-ophenone): 0.4-0.6%；
Triethanolamine: 0.09-0.11%；
Rose (ROSA RUGOSA) Hua Shui: 5-8%；
Water: 77.75-84.64%；
The ingredient of the GC-04 are as follows: decoyl hydroximic acid/glycerol caprylate/parahydroxyacet-ophenone.
Card wave is also referred to as carbomer (carbomer) in invention, is the acrylic acid being crosslinked with pentaerythrite etc. with acrylic acid
Crosslinked resin is a kind of very important rheology control agent, and the card wave after neutralization is outstanding gel-type vehicle, there is thickening suspension etc.
Important use, simple process, stability is good, is widely used in lotion, cream, in gel.
Hydroxyethylmethylcellulose (HEMC) is that ethylene oxide substituent group is introduced in methylcellulose (MC) in the present invention
(MS0.3~0.4) is made, and salt tolerance is better than unmodified polymer, and the gelling temp of HEMC is also compared with MC high.
Hyaluronic acid also known as sodium hyaluronate in the present invention are a kind of acid mucopolysaccharides.It is the tender important foundation object of skin water
Matter, itself is also a kind of ingredient of human body, it has special water retention, and deal is more up to 100 times of itself weight, is
The best substance of moisture retention in presently found nature, referred to as ideal natural moisturizing factor.It can improve skin battalion
Support metabolism, make skin it is tender, it is smooth, go wrinkle, increase elasticity, prevent aging, be good Transdermal absorption again while moisturizing
Promotor.It is used cooperatively with other nutritional ingredients, the more preferable effect for promoting nutrient absorption can be played.
Sodium Hyaluronate itself is one of composition of human skin in the present invention, is a kind of acidity that distribution is most wide in human body
Glutinous sugar, is present in the matrix of connective tissue, has good moisture-keeping function.Sodium Hyaluronate has good moisture-keeping function,
Using more in cosmetic field.
Hyaluronic acid product is hydrolyzed in the present invention following features: 1. molecular weight are ultralow, and the thousands of oligomerization of molecular weight is transparent
Matter acid.2. the permeability of permeability product is strong, can penetrate to the skin cuticula, directly generate nutrition reparation to keratoderma
Effect.It is 6-7 times of common molecular HA moisture retention 3. the moisture retention of moisture retention product is only second to ceramide.4. common molecular
HA skin surface form a film, but it is easy to clean fall, advantage is that skin sense is good！Ultra-low molecular HA skin surface can and skin
Cell combination, not easy to clean falls, and forms very strong moisturizing support and protective effect to skin！
Acetylation Sodium Hyaluronate is to be obtained by natural moisturizing factor Sodium Hyaluronate (HA) through acetylization reaction in the present invention
It arrives.The introducing of acetyl group, makes AcHA have both hydrophily and lipophilicity, can play double moisturizing, repair stratum corneum barrier, improves skin
The bioactivity such as skin elasticity enable skin softness elastic so as to improve dry skin, roughened state.
Dipropylene glycol can also be used as coupling agent and moisturizer in a variety of different cosmetics applications in the present invention.It is this
Raw material has good moisture, and oil and hydrocarbon are total to molten ability, and smell is slight, to skin irritation very little.Together
Enantiomers are evenly distributed unanimously, and quality is splendid.
Propylene glycol can be used as wetting agent with glycerol or sorbierite cooperation in cosmetics, toothpaste and perfumed soap in the present invention.?
It is used as damping, even hair agent in hair dye, also serves as antifreezing agent, be also used to glassine paper, plasticizer and pharmaceuticals industry.
Glycerine is colourless sweet clear and bright thick liquid in the present invention.It is odorless.There is warm sweet taste.Be commonly called as glycerol can be used as it is molten
Agent, lubricant, medicament and sweetener.
Aloe barbadensis Miller (ALOE BARBADENSIS) leaf extract shows various bioactivity in the present invention, is
The important additive of cosmetics.From it to the facilitation of fibrin growth, to the inhibition of elastin laminin, to collagen
Synthesis and the scavenging effect to free radical illustrate to play the role of good skin-active, anti-aging；There is promotion to make cholesterine synthesis
With, facilitate change sebum composition, reduce it is glossy and increase skin soft and moist degree；There is antibacterial anti-inflammatory and moisturizing simultaneously
Effect.
Allantoin is nontoxic one kind, tasteless and nonirritant, without hypersensitive white powder in the present invention, mainly does skin
Conditioner, protective agent use, and can help that skin is anti-inflammatory, releives and promotes cell repair.Allantoin can reduce corneocyte
Adhesion strength, accelerate epidermal cell update.It is some to have irritating cosmetics or anti-inflammatory calm containing tartaric acid, vitamin A
After-sun restorative product, which can all add allantoin, enhances its repair ability.
Biocare GC-04 contains natural fatty acid glyceride, decoyl hydroximic acid and natural antioxidant in the present invention
Parahydroxyacet-ophenone, wherein fatty acid glyceride is a kind of active skull cap components being present in human breast milk, can enhance new life
Diseases in infants is resisted and immunity.Biocare GC-04 has good affinity to skin, not only have moisturizing, moisturizing function,
Simultaneously can effectively control most of bacteriums and mould rambunctious in cosmetics, can satisfy completely " no added " concept or
To the formula demanding cosmetics series of mildness, such as facial mask, in antiallergic and infant's product.
Water in the present invention is deionized water, is solvent.
Triethanolamine and Acritamer 940 play the role of neutralizing thickening in the present invention.
Rose (ROSA RUGOSA) Hua Shui has the function of removing free radical in the present invention, illustrates may be used as anti-oxidant
Agent prevents aging；Cell activity can be enhanced, there is skin-active effect；Also there is certain inhibiting effect to tyrosinase, beauty can be assisted
It is white.
The two of task of the present invention realize by following technical solution:
A kind of a kind of above-mentioned preparation method of hyaluronic acid (sodium hyaluronate) stoste, comprising the following steps:
A, weigh Acritamer 940 by quality proportioning, water be made 2% carbomer solution, with homogenizer beat to exquisiteness；
B, weigh QP-100 hydroxyethyl cellulose by quality proportioning, water be made 2% hydroxyethyl cellulose solution, be heated to
Transparency liquid；
C, hyaluronic acid, Sodium Hyaluronate, hydrolysis hyaluronic acid, acetylation Sodium Hyaluronate, water are weighed by quality proportioning
Be respectively prepared 2% hyaluronic acid solution, hyaluronic acid in deionized water stirring and dissolving to transparent；
D, above-mentioned A, B, component C and dipropylene glycol, propylene glycol, glycerol, aloe barbadensis Miller leaf extract, allantoin, GC-
04, rose wate, surplus deionized water be dispersed with stirring, then with homogenizer homogeneous to no particle；
E, triethanolamine is added in above-mentioned D under stiring, is stirred until homogeneous to get hyaluronic acid stoste Material is arrived.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to embodiments, to the present invention
It is further elaborated.It should be appreciated that saying that the specific embodiment of description is used only for explaining the present invention herein, it is not used to
Limit the present invention.
A kind of hyaluronic acid (sodium hyaluronate) stoste, is made by the component of following quality proportionings:
A kind of hyaluronic acid (sodium hyaluronate) stoste, is made by the component of following quality proportionings:
Acritamer 940: 0.08-0.12%；
QO-100 hydroxyethyl cellulose: 0.09-0.12%；
Hyaluronic acid: 0.2-0.5%；
Sodium Hyaluronate: 0.2-0.5%；
Hydrolyze hyaluronic acid: 0.2-0.5%；
Acetylation Sodium Hyaluronate: 0.2-0.5%；
Dipropylene glycol: 3.8-4.2%；
Propylene glycol: 1.8-2.1%；
Glycerol: 1.8-2.2%；
Aloe barbadensis Miller (ALOE BARBADENSIS) leaf extract: 1-2%；
Allantoin: 0.5-0.8%；
GC-04 (decoyl hydroximic acid/glycerol caprylate/parahydroxyacet-ophenone): 0.4-0.6%；
Triethanolamine: 0.09-0.11%；
Rose (ROSA RUGOSA) Hua Shui: 5-8%；
Water: 77.75-84.64%；
The ingredient of the GC-04 are as follows: decoyl hydroximic acid/glycerol caprylate/parahydroxyacet-ophenone.
Card wave is also referred to as carbomer (carbomer) in invention, is the acrylic acid being crosslinked with pentaerythrite etc. with acrylic acid
Crosslinked resin is a kind of very important rheology control agent, and the card wave after neutralization is outstanding gel-type vehicle, there is thickening suspension etc.
Important use, simple process, stability is good, is widely used in lotion, cream, in gel.
Hydroxyethylmethylcellulose (HEMC) is that ethylene oxide substituent group is introduced in methylcellulose (MC) in the present invention
(MS0.3~0.4) is made, and salt tolerance is better than unmodified polymer, and the gelling temp of HEMC is also compared with MC high.
Hyaluronic acid also known as sodium hyaluronate in the present invention are a kind of acid mucopolysaccharides.It is the tender important foundation object of skin water
Matter, itself is also a kind of ingredient of human body, it has special water retention, and deal is more up to 100 times of itself weight, is
The best substance of moisture retention in presently found nature, referred to as ideal natural moisturizing factor.It can improve skin battalion
Support metabolism, make skin it is tender, it is smooth, go wrinkle, increase elasticity, prevent aging, be good Transdermal absorption again while moisturizing
Promotor.It is used cooperatively with other nutritional ingredients, the more preferable effect for promoting nutrient absorption can be played.
Sodium Hyaluronate itself is one of composition of human skin in the present invention, is a kind of acidity that distribution is most wide in human body
Glutinous sugar, is present in the matrix of connective tissue, has good moisture-keeping function.Sodium Hyaluronate has good moisture-keeping function,
Using more in cosmetic field.
Hyaluronic acid product is hydrolyzed in the present invention following features: 1. molecular weight are ultralow, and the thousands of oligomerization of molecular weight is transparent
Matter acid.2. the permeability of permeability product is strong, can penetrate to the skin cuticula, directly generate nutrition reparation to keratoderma
Effect.It is 6-7 times of common molecular HA moisture retention 3. the moisture retention of moisture retention product is only second to ceramide.4. common molecular
HA skin surface form a film, but it is easy to clean fall, advantage is that skin sense is good！Ultra-low molecular HA skin surface can and skin
Cell combination, not easy to clean falls, and forms very strong moisturizing support and protective effect to skin！
Acetylation Sodium Hyaluronate is to be obtained by natural moisturizing factor Sodium Hyaluronate (HA) through acetylization reaction in the present invention
It arrives.The introducing of acetyl group, makes AcHA have both hydrophily and lipophilicity, can play double moisturizing, repair stratum corneum barrier, improves skin
The bioactivity such as skin elasticity enable skin softness elastic so as to improve dry skin, roughened state.
Dipropylene glycol can also be used as coupling agent and moisturizer in a variety of different cosmetics applications in the present invention.It is this
Raw material has good moisture, and oil and hydrocarbon are total to molten ability, and smell is slight, to skin irritation very little.Together
Enantiomers are evenly distributed unanimously, and quality is splendid.
Propylene glycol can be used as wetting agent with glycerol or sorbierite cooperation in cosmetics, toothpaste and perfumed soap in the present invention.?
It is used as damping, even hair agent in hair dye, also serves as antifreezing agent, be also used to glassine paper, plasticizer and pharmaceuticals industry.
Glycerine is colourless sweet clear and bright thick liquid in the present invention.It is odorless.There is warm sweet taste.Be commonly called as glycerol can be used as it is molten
Agent, lubricant, medicament and sweetener.
Aloe barbadensis Miller (ALOE BARBADENSIS) leaf extract shows various bioactivity in the present invention, is
The important additive of cosmetics.From it to the facilitation of fibrin growth, to the inhibition of elastin laminin, to collagen
Synthesis and the scavenging effect to free radical illustrate to play the role of good skin-active, anti-aging；There is promotion to make cholesterine synthesis
With, facilitate change sebum composition, reduce it is glossy and increase skin soft and moist degree；There is antibacterial anti-inflammatory and moisturizing simultaneously
Effect.
Allantoin is nontoxic one kind, tasteless and nonirritant, without hypersensitive white powder in the present invention, mainly does skin
Conditioner, protective agent use, and can help that skin is anti-inflammatory, releives and promotes cell repair.Allantoin can reduce corneocyte
Adhesion strength, accelerate epidermal cell update.It is some to have irritating cosmetics or anti-inflammatory calm containing tartaric acid, vitamin A
After-sun restorative product, which can all add allantoin, enhances its repair ability.
Biocare GC-04 contains natural fatty acid glyceride, decoyl hydroximic acid and natural antioxidant in the present invention
Parahydroxyacet-ophenone, wherein fatty acid glyceride is a kind of active skull cap components being present in human breast milk, can enhance new life
Diseases in infants is resisted and immunity.Biocare GC-04 has good affinity to skin, not only have moisturizing, moisturizing function,
Simultaneously can effectively control most of bacteriums and mould rambunctious in cosmetics, can satisfy completely " no added " concept or
To the formula demanding cosmetics series of mildness, such as facial mask, in antiallergic and infant's product.
Water in the present invention is deionized water, is solvent.
Triethanolamine and Acritamer 940 play the role of neutralizing thickening in the present invention.
Rose (ROSA RUGOSA) Hua Shui has the function of removing free radical in the present invention, illustrates may be used as anti-oxidant
Agent prevents aging；Cell activity can be enhanced, there is skin-active effect；Also there is certain inhibiting effect to tyrosinase, beauty can be assisted
It is white.
The two of task of the present invention realize by following technical solution:
A kind of a kind of above-mentioned preparation method of hyaluronic acid (sodium hyaluronate) stoste, comprising the following steps:
A, weigh Acritamer 940 by quality proportioning, water be made 2% carbomer solution, with homogenizer beat to exquisiteness；
B, weigh QP-100 hydroxyethyl cellulose by quality proportioning, water be made 2% hydroxyethyl cellulose solution, be heated to
Transparency liquid；
C, hyaluronic acid, Sodium Hyaluronate, hydrolysis hyaluronic acid, acetylation Sodium Hyaluronate, water are weighed by quality proportioning
Be respectively prepared 2% hyaluronic acid solution, hyaluronic acid in deionized water stirring and dissolving to transparent；
D, above-mentioned A, B, component C and dipropylene glycol, propylene glycol, glycerol, aloe barbadensis Miller leaf extract, allantoin, GC-
04, rose wate, surplus deionized water be dispersed with stirring, then with homogenizer homogeneous to no particle；
E, triethanolamine is added in above-mentioned D under stiring, is stirred until homogeneous to get hyaluronic acid stoste Material is arrived.
Hyaluronic acid (sodium hyaluronate) stoste of the invention, it can achieve multi-level, efficient moisturizing reparation and whitening
The effect of beautiful skin anti-wrinkle.This is because hyaluronic acid stoste of the present invention is made of the hyaluronic acid of various molecular weights size, greatly
Molecular weight hyaluronic acid can form one layer of ventilative film in skin surface, it is wet make skin smooth, and can obstruct alien bacteria, ash
Dirt, ultraviolet light intrusion, protect the skin from infringement.Micromolecule hyaluronic acid can penetrate into corium, have mild dilation blood capillary
Pipe increases blood circulation, improves intermediate supersession, promotes skin-nourishing absorption, has the function of stronger wrinkle-chasing, can increase skin
Skin elasticity, delay skin aging, bright color.
Above description is only embodiments herein and the explanation to institute's application technology principle.Those skilled in the art answer
Work as understanding, invention scope involved in the application, however it is not limited to technical solution made of the specific combination of above-mentioned technical characteristic,
It should also cover in the case where not departing from the inventive concept simultaneously, carry out any group by above-mentioned technical characteristic or its equivalent feature
The other technical solutions closed and formed.Such as features described above and (but being not limited to) disclosed herein have the skill of similar functions
Art feature is replaced mutually and the technical solution that is formed.
Claims (2)
1. a kind of hyaluronic acid (sodium hyaluronate) stoste, which is characterized in that be made by the component of following quality proportionings:
Acritamer 940: 0.08-0.12%；
QO-100 hydroxyethyl cellulose: 0.09-0.12%；
Hyaluronic acid: 0.2-0.5%；
Sodium Hyaluronate: 0.2-0.5%；
Hydrolyze hyaluronic acid: 0.2-0.5%；
Acetylation Sodium Hyaluronate: 0.2-0.5%；
Dipropylene glycol: 3.8-4.2%；
Propylene glycol: 1.8-2.1%；
Glycerol: 1.8-2.2%；
Aloe barbadensis Miller (ALOE BARBADENSIS) leaf extract: 1-2%；
Allantoin: 0.5-0.8%；
GC-04 (decoyl hydroximic acid/glycerol caprylate/parahydroxyacet-ophenone): 0.4-0.6%；
Triethanolamine: 0.09-0.11%；
Rose (ROSA RUGOSA) Hua Shui: 5-8%；
Water: 77.75-84.64%；
The ingredient of the GC-04 are as follows: decoyl hydroximic acid/glycerol caprylate/parahydroxyacet-ophenone.
2. one kind is based on a kind of preparation method of hyaluronic acid (sodium hyaluronate) stoste described in claim 1, which is characterized in that including
Following steps:
A, weigh Acritamer 940 by quality proportioning, water be made 2% carbomer solution, with homogenizer beat to exquisiteness；
B, weigh QP-100 hydroxyethyl cellulose by quality proportioning, water be made 2% hydroxyethyl cellulose solution, be heated to transparent
Liquid；
C, hyaluronic acid, Sodium Hyaluronate, hydrolysis hyaluronic acid, acetylation Sodium Hyaluronate, water is weighed by quality proportioning to distinguish
Be made 2% hyaluronic acid solution, hyaluronic acid in deionized water stirring and dissolving to transparent；
D, above-mentioned A, B, component C and dipropylene glycol, propylene glycol, glycerol, aloe barbadensis Miller leaf extract, allantoin, GC-04,
Rose wate, surplus deionized water be dispersed with stirring, then with homogenizer homogeneous to no particle；
E, triethanolamine is added in above-mentioned D under stiring, is stirred until homogeneous to get hyaluronic acid stoste Material is arrived.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910044762.4A CN109730953A (en) | 2019-01-17 | 2019-01-17 | A kind of hyaluronic acid (sodium hyaluronate) stoste and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910044762.4A CN109730953A (en) | 2019-01-17 | 2019-01-17 | A kind of hyaluronic acid (sodium hyaluronate) stoste and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109730953A true CN109730953A (en) | 2019-05-10 |
Family
ID=66365164
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910044762.4A Pending CN109730953A (en) | 2019-01-17 | 2019-01-17 | A kind of hyaluronic acid (sodium hyaluronate) stoste and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109730953A (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110302081A (en) * | 2019-07-29 | 2019-10-08 | 广州药妆日用化工有限公司 | A kind of dual sodium hyaluronate stoste and preparation method thereof |
| WO2021077320A1 (en) * | 2019-10-23 | 2021-04-29 | L'oreal | Composition for caring for the skin |
| CN113081892A (en) * | 2021-04-08 | 2021-07-09 | 珠海朗祺生物科技有限公司 | Composition containing acetyl chitosamine and having moisturizing effect as well as preparation method and application of composition |
| CN113662881A (en) * | 2021-09-30 | 2021-11-19 | 水羊化妆品制造有限公司 | Composition for repairing sensitive skin, preparation method and application thereof |
| WO2022100519A1 (en) * | 2020-11-11 | 2022-05-19 | 华熙生物科技(天津)有限公司 | Hyaluronic acid composition having permeation-promoting effect, preparation method therefor and use thereof |
| CN114557946A (en) * | 2022-03-22 | 2022-05-31 | 无锡知妍生物科技有限公司 | Hyaluronic acid gel and preparation method thereof |
| CN114903815A (en) * | 2022-05-24 | 2022-08-16 | 华熙生物科技股份有限公司 | Composition for promoting aquaporin expression, application thereof and moisturizing product |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108478453A (en) * | 2018-02-26 | 2018-09-04 | 广州丽彦妆生物科技有限公司 | Hyaluronic acid face mask liquid and preparation method thereof |
-
2019
- 2019-01-17 CN CN201910044762.4A patent/CN109730953A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108478453A (en) * | 2018-02-26 | 2018-09-04 | 广州丽彦妆生物科技有限公司 | Hyaluronic acid face mask liquid and preparation method thereof |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110302081A (en) * | 2019-07-29 | 2019-10-08 | 广州药妆日用化工有限公司 | A kind of dual sodium hyaluronate stoste and preparation method thereof |
| WO2021077320A1 (en) * | 2019-10-23 | 2021-04-29 | L'oreal | Composition for caring for the skin |
| CN114585348A (en) * | 2019-10-23 | 2022-06-03 | 莱雅公司 | Composition for caring skin |
| WO2022100519A1 (en) * | 2020-11-11 | 2022-05-19 | 华熙生物科技(天津)有限公司 | Hyaluronic acid composition having permeation-promoting effect, preparation method therefor and use thereof |
| CN113081892A (en) * | 2021-04-08 | 2021-07-09 | 珠海朗祺生物科技有限公司 | Composition containing acetyl chitosamine and having moisturizing effect as well as preparation method and application of composition |
| CN113662881A (en) * | 2021-09-30 | 2021-11-19 | 水羊化妆品制造有限公司 | Composition for repairing sensitive skin, preparation method and application thereof |
| CN114557946A (en) * | 2022-03-22 | 2022-05-31 | 无锡知妍生物科技有限公司 | Hyaluronic acid gel and preparation method thereof |
| CN114557946B (en) * | 2022-03-22 | 2024-02-23 | 无锡知妍生物科技有限公司 | Hyaluronic acid gel's preparation facilities |
| CN114903815A (en) * | 2022-05-24 | 2022-08-16 | 华熙生物科技股份有限公司 | Composition for promoting aquaporin expression, application thereof and moisturizing product |
| CN114903815B (en) * | 2022-05-24 | 2024-06-21 | 华熙生物科技股份有限公司 | Composition for promoting aquaporin expression, application thereof and moisturizing product |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN109730953A (en) | A kind of hyaluronic acid (sodium hyaluronate) stoste and preparation method thereof | |
| CN106727164B (en) | A kind of moisture-keeping composition and its preparation method and application | |
| CN106137786B (en) | A kind of anti-ageing composition of hyaluronic acid and its preparation method and application | |
| CN102440926B (en) | Daffodil whitening cream cosmetic | |
| CN102525864B (en) | Marine biological functional cosmetic for removing acne | |
| CN107496278A (en) | Carnosine snow face frost | |
| CN107714504A (en) | A kind of same human-like collagen composition and its applied in cosmetics | |
| CN108478453A (en) | Hyaluronic acid face mask liquid and preparation method thereof | |
| CN108125892A (en) | A kind of marine organism moisture-retention anti-aging cosmetics composition | |
| CN104906015A (en) | Cubilose whitening and beautifying mask | |
| CN107496310A (en) | A kind of facial treatment essence liquid and preparation method thereof | |
| CN104644507A (en) | Nursing cream composition | |
| CN102440927A (en) | Daffodil whitening toning lotion cosmetic | |
| CN108524406A (en) | A kind of Golden flower facial mask and preparation method thereof | |
| CN109381408A (en) | A kind of anti-ageing Essence of moisturizing and preparation method thereof | |
| CN111067847A (en) | Reverse-aging spray preparation with skin brightening and anti-wrinkle effects and preparation method thereof | |
| CN110833519A (en) | Soothing and moisturizing mask liquid containing industrial hemp leaf extract and preparation method thereof | |
| AU2013362634B2 (en) | Bee venom composition with effects of protecting and beautifying lip | |
| CN109700750A (en) | A kind of anti-ageing face mask and preparation method thereof containing sodium hyaluronate | |
| CN113081883A (en) | PHAR HERMETIU EKEDONE repairing essence lotion and production process thereof | |
| CN108478464A (en) | A kind of skin makeup peptide facial mask liquid and preparation method thereof | |
| CN105534815B (en) | A kind of skin care compositions and preparation method thereof containing lotus active constituent | |
| CN105560090A (en) | Skin-activating moisturizing anti-wrinkle face-moisturizing cream | |
| CN111743850A (en) | Edible ampelopsis grossedentata hydrogel mask and preparation method thereof | |
| CN106309227A (en) | Hyaluronic acid stoste |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190510 |