CN108671171A - A kind of drug and preparation method thereof for treating brain tumor - Google Patents
A kind of drug and preparation method thereof for treating brain tumor Download PDFInfo
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Abstract
The invention discloses a kind of drugs and preparation method thereof for treating brain tumor, it is mainly to be prepared according to a certain weight ratio You Amorphophalus rivieri, mock-strawberry, Chinese lobelia, Sculellaria barbata, Prunella vulgaris, radix semiaquilegiae, Paris polyphylla, rhizome of cyrtomium, chinaroot greenbrier, the root of Dahurain angelica, Rhizoma Chuanxiong, drug of the present invention has the function of clearing heat and detoxicating, resolving sputum scattered plot, cool liver arresting convulsion, promote breath and open depression, promoting blood circulation and stopping pain, brain tumor is quick, good effect for treating, and does not recur.
Description
Technical field
The present invention relates to a kind of drugs and preparation method thereof for treating brain tumor, belong to the field of Chinese medicines.
Technical background
Brain tumor refers to the nervous system neoplasm betided in cranial cavity, including originate from neural epithelium, peripheral nerve, meninx and
The tumour of reproduction cell, lymph and hematopoietic neoplasm, the craniopharyngioma and granular cell tumor and metastatic of sella region are swollen
Tumor.Chinese medicine then thinks that brain tumor is related with acute purulent lymphadenitis cohesion, qi and blood pent-up, liver and gallbladder damp-heat, the insufficiency of both the spleen and the kindey.Due to western medicine side effect
Greatly, thus people to the Chinese medicine of effectively treating brain tumor, there are great demands, up to now, it has not been found that about this hair
Bright related report.
Invention content
The present inventor is on the basis of hospital handed down from one's ancestors, and the verification repeatedly Jing Guo clinical test, has finally found and effectively controls
The drug of brain tumor is treated, so as to complete the present invention.
It is an object of the invention to provide a kind of Chinese medicine compositions of effective treatment brain tumor.
Another aim of the present invention is to provide the preparation methods of the Chinese medicine composition.
It is Shi Xuan Ze Amorphophalus rivieris of the present invention, mock-strawberry, Chinese lobelia, Sculellaria barbata, Prunella vulgaris, radix semiaquilegiae, Paris polyphylla, rhizome of cyrtomium, chinaroot greenbrier, white
The root of Dahurian angelica, Rhizoma Chuanxiong, caulis bambusae in taenian, seaweed, kelp drug are combined preparation, make each efficacy of drugs generate collaboration these pharmaceutical compositions
Effect, so as to effectively treat brain tumor.Wherein, Xuan Yong Amorphophalus rivieri be because its nature and flavor it is acrid in flavour and warm in nature, it is toxic, have resolving sputum scattered plot, the row stasis of blood
The function of detumescence controls phlegm and coughs, and stagnates, malaria, Amenorrhea, traumatic injury, carbuncle swells, furunculosis, erysipelas, burn.Select mock-strawberry be because
For its nature and flavor sweetness and bitterness, tremble with fear, it is toxic, there are heat-clearing, cool blood to subside a swelling, the function of removing toxic substances controls pyreticosis , Jing Epilepsy, coughs, and spits blood, and throat is swollen
Bitterly, dysentery, carbuncle swells, furunculosis, snakebite and bugbite, burn.It is because of its nature and flavor sweet and neutral to select Chinese lobelia, and advantageous water is subsided a swelling, solution
The function of poison, Yellow River harnessing subcutaneous ulcer, oedema, expansion, diarrhea, dysentery, snakebite, furunculosis, pyogenic infections, eczema, tinea, bruises and spasms.Choosing
It is to tremble with fear because its is bitter in taste, have heat-clearing, the function of removing toxic substances to control abscess of throat, scald, traumatic injury, wet sore with Sculellaria barbata.Choosing
It is to tremble with fear because of its nature and flavor toil, enter liver, gallbladder channel with Prunella vulgaris, has clearing liver, the function of dissipating bind to control scrofula, goiter and tumor, acute mastitis, breast
Cancer, mesh pearl nyctalgia, photophobia are shed tears, vertigo, facial paralysis, arthralgia and myalgia, pulmonary tuberculosis, acute icteric catarrhal jaundice,
Metrorrhagia, under.Selecting radix semiaquilegiae is trembled with fear because of its nature and flavor sweetness and bitterness, is entered spleen, small intestine, bladder three and is passed through, has heat-clearing, detoxify, detumescence,
Dissipating bind, the function of diuresis control carbuncle swells, scrofula, furunculosis, stranguria with turbid discharge, under band, cough due to deficiency of the lung, and hernia , Dian Epilepsy, child convulsion, hemorrhoid,
Traumatic injury.Selecting Paris polyphylla is slightly cold, slightly poisonous, return liver warp has clearing heat and detoxicating, swelling and pain relieving, cool liver fixed because its is bitter in taste
Frightened function controls furunculosis carbuncle swells, abscess of throat, venomous snake bite, the pain of injury caused by falling and tumbling, convulsion.It is because of its nature and flavor to select rhizome of cyrtomium
Hardship, it is cool, enter liver, stomach, kills ascarid, silk ribbon, pinworm, heat-clearing, removing toxic substances, cool blood, the function of hemostasis controls anemopyretic cold, damp and hot ecchymosis,
It spits blood, bleeding from five sense organs or subcutaneous tissue, hematochezia, bloody flux, metrorrhagia, under.It is to enter sufficient cloudy, few the moon of fainting because of its nature and flavor sweet, warm, have to select chinaroot greenbrier
Wind-damp dispelling, diuresis, the function for poison of subsiding a swelling control arthralgia, and muscle is numb, diarrhea, dysentery, oedema, gonorrhoea, furunculosis, pyogenic infections,
Scrofula, hemorrhoid.It is to enter lung, spleen, stomach because its nature and flavor is acrid in flavour and warm in nature to select the root of Dahurain angelica, has wind-dispelling, eliminating dampness to subside a swelling, the function of analgesic,
Control headache, pain in the supra-orbital bone, dentalgia, nasosinusitis, cold-dampness stomachache, intestines wind anal fistula, leukorrhea with reddish discharge, ulcer sores, skin itchy, mange.
It is to enter liver, gallbladder channel because its nature and flavor is acrid in flavour and warm in nature, there is promote breath and open depression, dispel pathogenic wind and remove dampness, the function of promoting blood circulation and stopping pain is controlled air-cooled to select Rhizoma Chuanxiong
Headache rotation is dizzy, hypochondriac pain abdomen pain, arthritis muscle contraction, Amenorrhea, difficult labour, postpartum stasis block pain, ulcer sores.It is because of its property to select caulis bambusae in taenian
It is sweet in flavor, it is cool, enter stomach, gallbladder channel, there is a heat-clearing, cool blood, resolving sputum, the function of antiemetic controls dysphoria with smothery sensation vomiting, hiccup, and the asthma of phlegm heat-syndrome cough is spitted blood,
Bleeding from five sense organs or subcutaneous tissue, uterine bleeding, vomiting during early pregnancy, movement of the foetus , Jing Epilepsy.It is to tremble with fear because its is bitter in taste salty, enter lung, spleen, kidney channel, there is softening hard masses, disappear to select seaweed
Phlegm, Li Shui, the function of expelling the heat-evil control scrofula, goiter and tumor, accumulation, oedema, tinea pedis, testiclar gall.It is because of its nature and flavor to select kelp
It is salty, it trembles with fear, enters stomach, there are softening hard masses, the function of row water to control scrofula, goiter and tumor is dysphagic, oedema, testiclar gall, under band.
The drug dose of instant component is also to be obtained by plenty of explorations of the inventor, and the dosage of each component is following heavy
All tools have a better effect in amount range：
25-35 grams of Amorphophalus rivieri, 25-35 grams of mock-strawberry, 10-20 grams of Chinese lobelia, 10-20 grams of Sculellaria barbata, 10-20 grams of Prunella vulgaris, radix semiaquilegiae
10-20 grams, 10-20 grams of Paris polyphylla, 10-20 grams of rhizome of cyrtomium, 10-20 grams of chinaroot greenbrier, 5-15 grams of the root of Dahurain angelica, 10-15 grams of Rhizoma Chuanxiong, caulis bambusae in taenian 7-12
Gram, 7-12 grams of seaweed, 10-15 grams of kelp.
Preferably：
30 grams of Amorphophalus rivieri, 15 grams of Chinese lobelia, 15 grams of Sculellaria barbata, 15 grams of Prunella vulgaris, 15 grams of radix semiaquilegiae, 15 grams of Paris polyphylla, passes through at 30 grams of mock-strawberry
15 grams many, 15 grams of chinaroot greenbrier, 10 grams of the root of Dahurain angelica, 12 grams of Rhizoma Chuanxiong, 9 grams of caulis bambusae in taenian, 9 grams of seaweed, 12 grams of kelp.
The preparation method of drug of the present invention is as follows
One, it stocks up
1, Amorphophalus rivieri：Autumn end harvests, and picks net impurity, dries；
2, mock-strawberry：Net impurity is picked, is dried；
3, Chinese lobelia：Summer harvests, and band has been eradicated, and cleans, dries or dry in the shade；
4, Sculellaria barbata：Impurity is removed, cleans, slightly moistens, segment, it is dry；
5, Prunella vulgaris：Crude drug is taken, discarding stalk, blade and impurity is removed, weeds out grey bits；
6, radix semiaquilegiae：Clear water is cleaned, and slice dries；
7, Paris polyphylla：Remove fibrous root, cleaning, drying；
8, rhizome of cyrtomium：It is slightly soaked, is taken out with clear water, each watering is primary sooner or later, softens, and is sliced, dries；
9, chinaroot greenbrier：Active compound is embathed with clear water, moisturizes, thinly slices, dry；
10, the root of Dahurain angelica：Net impurity is picked, is eluted with water, is impregnated, is pulled out and moisturize, when slightly shining to crust without soapy feeling, then after bored profit, cut
Piece is dried；
11, Rhizoma Chuanxiong：Impurity is picked, large and small is separated, is soaked in water, solarization is dried in the air, and is sliced after bored profit, dry；
12, caulis bambusae in taenian：Hard bamboo stick, impurity are removed, grey bits are shaked off, is kneaded into small group or segment；
13, seaweed：Impurity is picked, is slightly floated with water, is slightly dried in the air, segment is dried；
14, kelp：Impurity is picked, is rinsed with water, wide silk is cut into, dries.
Two, it prepares
1, by the weight Amorphophalus rivieris, mock-strawberry, Chinese lobelia, Sculellaria barbata, Prunella vulgaris, radix semiaquilegiae, Paris polyphylla, rhizome of cyrtomium, chinaroot greenbrier, the root of Dahurain angelica,
Rhizoma Chuanxiong, caulis bambusae in taenian, seaweed, kelp are put into decocting container, add 6 times of water amount, after impregnating 100 minutes, high heat decoction boiling, then with literary
Fire decocts 20 minutes, filters to obtain first time decoction liquor, first time decoction liquor is poured into container；
2, the dregs of a decoction of filtering are added into 4 times of amounts of water, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second of decoction liquor；
3, it decoction liquor will be mixed evenly twice, and be divided into 3 doses and take.
Acute purulent lymphadenitis cohesion, qi and blood pent-up, liver and gallbladder damp-heat, the insufficiency of both the spleen and the kindey
Zu Fang Zhong Amorphophalus rivieri resolving sputum scattered plots, blood stasis, mock-strawberry have heat-clearing, and cool blood, detumescence, both functions of removing toxic substances are monarch drug in a prescription；Half
Bian Lianli water is subsided a swelling, removing toxic substances, and it is ministerial drug, seven flavor medicine with Prunella vulgaris, radix semiaquilegiae, Paris polyphylla that Sculellaria barbata, which has heat-clearing, the function of removing toxic substances,
Play the effect of clearing heat and detoxicating resolving sputum scattered plot, inducing diuresis for removing edema, cool blood jointly, treatment brain tumor effect is comprehensive, and with it is clearing heat and detoxicating,
Based on resolving sputum scattered plot, it can effect a permanent cure；Paris polyphylla has clearing heat and detoxicating a, swelling and pain relieving, and the function of cool liver arresting convulsion is with rhizome of cyrtomium, chinaroot greenbrier, the root of Dahurain angelica
Adjutant；Rhizoma Chuanxiong has promote breath and open depression, dispels pathogenic wind and remove dampness, and the function of promoting blood circulation and stopping pain is that medicine is made to be to take stopgap measures with remaining all medicines.
Drug of the present invention has the function of clearing heat and detoxicating, resolving sputum scattered plot, cool liver arresting convulsion, promote breath and open depression, promoting blood circulation and stopping pain, is used for
Treat brain tumor, short treating period, quick, non-relapse after healing.
Specific implementation mode
Carry out the advantageous effect of the present invention is further explained the drug below by way of test example, these test examples include this hair
The animal toxicity test report of bright drug and clinical observation on the therapeutic effect data.
The animal toxicity test of [test example 1] drug of the present invention is reported：
Rabbit 30, male and female dual-purpose, 2.0-2.5kg of weight is taken to be divided to two groups, every group 15, one of which is tested for overdose
Group, another group is normal amount test group.Super quantity group is 20ml/kg, normal amount 10ml/kg, and administering mode gives for administration by gavage
Medicine even served 7 days twice daily, the reaction of observation administration daily, the results showed that two groups of rabbit activities, diet are normal, and drug is without bad
Toxic side effect.
The clinical observation on the therapeutic effect of [test example 2] drug of the present invention
1, general information
Accept brain tumor out-patient totally 39 for medical treatment.
2, diagnostic criteria
Classical symptom is：Headache, nausea and vomiting, dimmed, dizziness, spirit and consciousness obstacle etc. regarding object.
3, therapy
Above-mentioned medicament is selected, is taken to patient, each taking 1 dose, early daily, evening respectively takes 1 time, 30 days as a treatment course, continuously
It takes 2 course for the treatment of.
4, efficacy assessment standard
It is effective：Brain tumor symptom disappears, and spirit and consciousness restores normal, and follow-up is not recurred for 1 year；
It improves：The phenomenon that patient's headache, nausea and vomiting, dizziness dimmed depending on object, spirit and consciousness barrier, mitigates, and brain tumor symptom is bright
Aobvious to improve, constitution is gradually restored；
In vain：Improvement standard person is not achieved.
5, treatment results（It see the table below）
In above-mentioned treatment, with drug therapy Patients with Brain Tumors 39 of the present invention, as a result effective 30, obvious effective rate 76.92% is good
Turn 6, improvement rate 15.38%, invalid 3, total effective rate 92.3%.
Claims (3)
1. a kind of drug for treating brain tumor, it is characterised in that：It is made of the bulk pharmaceutical chemicals in following weight range：
25-35 grams of Amorphophalus rivieri, 25-35 grams of mock-strawberry, 10-20 grams of Chinese lobelia, 10-20 grams of Sculellaria barbata, 10-20 grams of Prunella vulgaris, radix semiaquilegiae
10-20 grams, 10-20 grams of Paris polyphylla, 10-20 grams of rhizome of cyrtomium, 10-20 grams of chinaroot greenbrier, 5-15 grams of the root of Dahurain angelica, 10-15 grams of Rhizoma Chuanxiong, caulis bambusae in taenian 7-12
Gram, 7-12 grams of seaweed, 10-15 grams of kelp.
2. drug according to claim 1, wherein the dosage of each bulk pharmaceutical chemicals is：
30 grams of Amorphophalus rivieri, 15 grams of Chinese lobelia, 15 grams of Sculellaria barbata, 15 grams of Prunella vulgaris, 15 grams of radix semiaquilegiae, 15 grams of Paris polyphylla, passes through at 30 grams of mock-strawberry
15 grams many, 15 grams of chinaroot greenbrier, 10 grams of the root of Dahurain angelica, 12 grams of Rhizoma Chuanxiong, 9 grams of caulis bambusae in taenian, 9 grams of seaweed, 12 grams of kelp.
3. the preparation method of drug according to claim 1 or claim 2, it includes the following steps：
（One）Stock
（1）Amorphophalus rivieri：Autumn end harvests, and picks net impurity, dries；
（2）Mock-strawberry：Net impurity is picked, is dried；
（3）Chinese lobelia：Summer harvests, and band has been eradicated, and cleans, dries or dry in the shade；
（4）Sculellaria barbata：Impurity is removed, cleans, slightly moistens, segment, it is dry；
（5）Prunella vulgaris：Crude drug is taken, discarding stalk, blade and impurity is removed, weeds out grey bits；
（6）Radix semiaquilegiae：Clear water is cleaned, and slice dries；
（7）Paris polyphylla：Remove fibrous root, cleaning, drying；
（8）Rhizome of cyrtomium：It is slightly soaked, is taken out with clear water, each watering is primary sooner or later, softens, and is sliced, dries；
（9）Chinaroot greenbrier：Active compound is embathed with clear water, moisturizes, thinly slices, dry；
（10）The root of Dahurain angelica：Net impurity is picked, is eluted with water, is impregnated, is pulled out and moisturize, when slightly shining to crust without soapy feeling, then after bored profit, cut
Piece is dried；
（11）Rhizoma Chuanxiong：Impurity is picked, large and small is separated, is soaked in water, solarization is dried in the air, and is sliced after bored profit, dry；
（12）Caulis bambusae in taenian：Hard bamboo stick, impurity are removed, grey bits are shaked off, is kneaded into small group or segment；
（13）Seaweed：Impurity is picked, is slightly floated with water, is slightly dried in the air, segment is dried；
（14）Kelp：Impurity is picked, is rinsed with water, wide silk is cut into, dries；
（Two）It prepares
（1）By the weight Amorphophalus rivieris, mock-strawberry, Chinese lobelia, Sculellaria barbata, Prunella vulgaris, radix semiaquilegiae, Paris polyphylla, rhizome of cyrtomium, chinaroot greenbrier, the root of Dahurain angelica,
Rhizoma Chuanxiong, caulis bambusae in taenian, seaweed, kelp are put into decocting container, add 6 times of water amount, after impregnating 100 minutes, high heat decoction boiling, then with literary
Fire decocts 20 minutes, filters to obtain first time decoction liquor, first time decoction liquor is poured into container；
（2）The dregs of a decoction of filtering are added into 4 times of amounts of water, are boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second of decoction liquor；
（3）It decoction liquor will be mixed evenly twice, and be divided into 3 doses and take.
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| CN201810854808.4A CN108671171A (en) | 2018-07-31 | 2018-07-31 | A kind of drug and preparation method thereof for treating brain tumor |
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