CN108653642A - 治疗糖尿病的药物及其制备方法 - Google Patents

治疗糖尿病的药物及其制备方法 Download PDF

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CN108653642A
CN108653642A CN201810746861.2A CN201810746861A CN108653642A CN 108653642 A CN108653642 A CN 108653642A CN 201810746861 A CN201810746861 A CN 201810746861A CN 108653642 A CN108653642 A CN 108653642A
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张春枝
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Abstract

本发明公开了一种治疗糖尿病的药物，以重量份为单位，制成其有效成分的原料药为：生石膏，黄芩，地骨皮，生知母，天门冬，麦门冬，天花粉，粳米，生甘草，山药，五味子，海蛤粉，海浮石，鸡内金，知母，党参，元参，生地黄，金樱子，桑螵蛸，沙苑子，益智仁，黄芪，益母草。本发明是治疗糖尿病的专用药物，具有清热凉血、养阴清热、泻火解毒、软坚散结、健脾益肺、滋阴补肾等功效，配方精妙，能有效保卫胰岛，降低血糖，提高免疫，疗效稳定，无毒副作用，经过临床实践，效果极好，具有很好的社会实用价值，易于推广。

Description

治疗糖尿病的药物及其制备方法
一、技术领域：
本发明涉及一种药物，特别涉及一种治疗糖尿病的药物，以及该药物的制备方法，属于中药及其制备技术领域。
二、背景技术：
糖尿病是一组以高血糖为特征的代谢性疾病。高血糖则是由于胰岛素分泌缺陷或其生物作用受损，或两者兼有引起。糖尿病时长期存在的高血糖，导致各种组织，特别是眼、肾、心脏、血管、神经的慢性损害、功能障碍。
糖尿病患者除了要注意饮食和增加运动外，药物治疗是不可避免的。糖尿病是一种慢性疾病，其并发症可以影响到全身的各个器官，很多患者刚开始选择服用化学性西药来治疗，很快血糖就降下来了，但是长期服用该药物会对身体各个器官都有危害，它是以阻断人体营养吸收为代价，是在药物对机体产生很大的伤害和副作用的情况下产生的。
发明内容：
本发明所要解决的技术问题是：提供一种无毒副作用、诊治效果好、可以从根本上治愈糖尿病的中药胶囊。
本发明为解决技术问题所采取的技术方案是：
一种治疗糖尿病的药物，以重量份为单位，制成其有效成分的原料药为：生石膏20～40份，黄芩15～35份，地骨皮10～30份，生知母15～35份，天门冬15～25份，麦门冬10～20份，天花粉15～35份，粳米10～20份，生甘草15～25份，山药10～30份，五味子15～35份，海蛤粉10～20份，海浮石15～25份，鸡内金15～35份，知母10～20份，党参15～35份，元参5～15份，生地黄15～35份，金樱子10～20份，桑螵蛸15～35份，沙苑子15～25份，益智仁15～35份，黄芪10～20份，益母草20～40份。
所述的治疗糖尿病的药物，以重量份为单位，制成其有效成分的原料药为：生石膏30份，黄芩25份，地骨皮20份，生知母25份，天门冬20份，麦门冬15份，天花粉25份，粳米15份，生甘草20份，山药20份，五味子25份，海蛤粉15份，海浮石20份，鸡内金25份，知母15份，党参25份，元参10份，生地黄25份，金樱子15份，桑螵蛸25份，沙苑子20份，益智仁25份，黄芪15份，益母草30份。
上面所述治疗糖尿病的药物的剂型为胶囊。
所述的治疗糖尿病药物的制备方法，其具体加工步骤如下：
A 、按配比称取上述各原材料，加４倍量的水，浸泡４０分钟后，煎煮６０分钟，煎煮液A和药渣A；
Ｂ、向药渣A中加入２倍量的水，煎煮４０分钟，得煎煮液B和药渣B；
Ｃ、合并２次煎煮液，静置12各小时，将上清液过200目筛，得滤液A；
D、将滤液A蒸发至稠膏状，停止加热，喷雾干燥，得干膏饼；
E、将干膏饼粉碎后，过40-80目筛，装入空心胶囊，即可。
本发明的积极有益效果如下：
1、本发明是治疗糖尿病的药物，是以祖国中医药理论为基础，结合多年临床实践，从祖国医药宝库中筛选出具有清热凉血、养阴清热、泻火解毒、软坚散结、健脾益肺、滋阴补肾功效的药物，该药物组分中：生石膏：味辛、甘，性微寒，归肺、胃经，具有清热泻火， 除烦止渴，收敛生肌之功效；黄芩：味苦，性寒，归心、肺、胆、大肠经，具有泻实火，除湿热，止血，安胎之功效；地骨皮：性寒，味甘，归肺、肝、肾经，具有清热，凉血之功效；生知母：性寒，味苦，归肺、胃、肾经，具有清热泻火，滋阴润燥之功效；天门冬：性平，味苦，归肾、肺经，主治阴虚发热，咳嗽吐血，肺痿，肺痈，咽喉肿痛，消渴，便秘，小便不利；麦门冬：味甘、微苦，性微寒，归肺、胃、心三经，具有滋阴润肺，益胃生津，清心除烦之功效；天花粉：味甘、微苦，性微寒，归肺、胃经，具有清热泻火，生津止渴，消肿排脓之功效；粳米：味甘，性平，归脾、胃经，具有补中益气，健脾和胃，除烦渴，止泻痢之功效；生甘草：味甘，性平，归心、肺、脾、胃经 ，具有补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药之功效；山药：性甘味平，归肺、脾、肾经，具有健脾，补肺，固肾，益精之功效；五味子：味酸、甘,性温，归肺、心、肾经，具有敛肺，滋肾，生津，收汗，涩精之功效；海蛤粉：味咸、性寒，归心、肾经，具有热，利水，化痰，软坚之功效；海浮石：性寒、味咸，归肺、肾经，具有清肺火，化老痰，软坚，通淋之功效；鸡内金：性平，味甘，归脾、胃、小肠、膀胱经，具有健胃消食，涩精止遗，通淋化石之功效；知母：性寒，味苦，归肺、胃、肾经，具有清热泻火，滋阴润燥之功效；党参：味甘，性平，归脾、肺经，具有补中益气，健脾益肺之功效；元参：味苦，性寒，具有清热凉血、养阴清热、泻火解毒、软坚散结之功效；生地黄：味苦，性凉，归心、肝、肾经，具有清热生津滋阴，养血之功效；金樱子: 味酸、甘、涩，性平，归肾、膀胱、大肠经，具有固精缩尿，固崩止带，涩肠止泻之功效；桑螵蛸：味甘、咸，性平，归肝、肾经，具有固精缩尿，补肾助阳之功效；沙苑子：味甘，性温，归肝、肾经，具有补肝，益肾，明目，固精之功效；益智仁：味辛，性温，归脾、肾经，具有温脾止泻摄涎，暖肾缩尿固精之功效；黄芪：味甘、性温，归肺、脾、肝、肾经；益母草：味辛苦、性凉，具有活血、祛淤、调经、消水之功效。
2、本发明配方精妙，能有效保卫胰岛，降低血糖，提高免疫，既是血糖抑制剂，又是胰岛素增敏剂，同时又增强胰岛素受体功能，疗效稳定，副作用少。
3、本发明以中医理论为基础，辨证施治为原则，能够有效的纠正代谢紊乱，消除症状，可达到预防各种急性或慢性并发症和伴随症的发生，延长寿命，降低病残率和病死率。
4、本发明为治疗糖尿病的专用药物，其药物的剂型为中药胶囊，制作简单，服用方便，成本低，经临床实践，治愈高达98％，具有很好的社会实用价值，易于推广。
临床典型病例：
病例1、李某，55岁，男，患糖尿病多年，多饮多食多尿，消瘦，易感染，血糖升高多年，近期出现肾功能衰竭，被诊断为、Ⅰ型糖尿病，经本药物治疗两个月后，痊愈，至今无复发。
病例2、张某，女，67岁，一年前出现多饮、多食、多尿，伴有消瘦，每日饮水量增多，饭量大增，夜尿频多，平均每晚8次，体重严重下降，被诊断为2型糖尿病，经本药物治疗一个半月后，痊愈，至今无复发。
病例3、患者女，68岁，患糖尿病3年有余，每逢血糖高时，伴随有头晕、口渴、乏力、口苦的情况，同时小便增加，经本药物治疗两个月后痊愈，至今未复发。
病例4、患者闭经3年，心烦热、多汗，耳鸣，情绪激动，头胀，心焖，双下肢出现浮肿的情况，经检查被诊断为糖尿病，经本药物治疗2个月后，痊愈至今无复发。
病例5、患者，男，60岁，初期表现：口干、多饮、多尿、多食、容易饥饿，但是患者并未重视，一个月以后症状加重，烦渴、多饮，并伴有乏力症状，经过检查被诊断为糖尿病，经本药物治疗两个月后，痊愈，至今无复发。
四、具体实施例：
下面结合具体实施例对本发明作进一步的解释和说明：
实施例1、一种治疗糖尿病的药物，以重量份为单位，制成其有效成分的原料药为：生石膏30份，黄芩25份，地骨皮20份，生知母25份，天门冬20份，麦门冬15份，天花粉25份，粳米15份，生甘草20份，山药20份，五味子25份，海蛤粉15份，海浮石20份，鸡内金25份，知母15份，党参25份，元参10份，生地黄25份，金樱子15份，桑螵蛸25份，沙苑子20份，益智仁25份，黄芪15份，益母草30份。
上面所述治疗糖尿病的药物的剂型为胶囊，其具体加工步骤如下：
A 、按配比称取上述各原材料，加４倍量的水，浸泡４０分钟后，煎煮６０分钟，煎煮液A和药渣A；
Ｂ、向药渣A中加入２倍量的水，煎煮４０分钟，得煎煮液B和药渣B；
Ｃ、合并２次煎煮液，静置12各小时，将上清液过200目筛，得滤液A；
D、将滤液A蒸发至稠膏状，停止加热，喷雾干燥，得干膏饼；
E、将干膏饼粉碎后，过40-80目筛，装入空心胶囊，即可。
实施例2、一种治疗糖尿病的药物，以重量份为单位，制成其有效成分的原料药为：生石膏20份，黄芩15份，地骨皮10份，生知母15份，天门冬15份，麦门冬10份，天花粉15份，粳米10份，生甘草15份，山药10份，五味子15份，海蛤粉10份，海浮石15份，鸡内金15份，知母10份，党参15份，元参5份，生地黄15份，金樱子10份，桑螵蛸15份，沙苑子15份，益智仁15份，黄芪10份，益母草20份。
实施例3、一种治疗糖尿病的药物，以重量份为单位，制成其有效成分的原料药为：生石膏40份，黄芩35份，地骨皮30份，生知母35份，天门冬25份，麦门冬20份，天花粉35份，粳米20份，生甘草25份，山药30份，五味子35份，海蛤粉20份，海浮石25份，鸡内金35份，知母20份，党参35份，元参15份，生地黄35份，金樱子20份，桑螵蛸35份，沙苑子25份，益智仁35份，黄芪20份，益母草40份。
实施例4、一种治疗糖尿病的药物，以重量份为单位，制成其有效成分的原料药为：生石膏27份，黄芩22份，地骨皮17份，生知母22份，天门冬19份，麦门冬14份，天花粉22份，粳米14份，生甘草19份，山药17份，五味子22份，海蛤粉14份，海浮石19份，鸡内金22份，知母14份，党参22份，元9份，生地黄22份，金樱子14份，桑螵蛸22份，沙苑子19份，益智仁22份，黄芪14份，益母草27份。
实施例5、一种治疗糖尿病的药物，以重量份为单位，制成其有效成分的原料药为：生石膏34份，黄芩29份，地骨皮24份，生知母29份，天门冬23份，麦门冬18份，天花粉29份，粳米18份，生甘草23份，山药24份，五味子29份，海蛤粉18份，海浮石23份，鸡内金29份，知母18份，党参29份，元参13份，生地黄29份，金樱子18份，桑螵蛸29份，沙苑子23份，益智仁29份，黄芪18份，益母草34份。

Claims (4)

1.一种治疗糖尿病的药物，其特征在于：以重量份为单位，制成其有效成分的原料药为：生石膏20～40份，黄芩15～35份，地骨皮10～30份，生知母15～35份，天门冬15～25份，麦门冬10～20份，天花粉15～35份，粳米10～20份，生甘草15～25份，山药10～30份，五味子15～35份，海蛤粉10～20份，海浮石15～25份，鸡内金15～35份，知母10～20份，党参15～35份，元参5～15份，生地黄15～35份，金樱子10～20份，桑螵蛸15～35份，沙苑子15～25份，益智仁15～35份，黄芪10～20份，益母草20～40份。
2.根据权利要求1所述的治疗糖尿病的药物，其特征在于：以重量份为单位，制成其有效成分的原料药为：生石膏30份，黄芩25份，地骨皮20份，生知母25份，天门冬20份，麦门冬15份，天花粉25份，粳米15份，生甘草20份，山药20份，五味子25份，海蛤粉15份，海浮石20份，鸡内金25份，知母15份，党参25份，元参10份，生地黄25份，金樱子15份，桑螵蛸25份，沙苑子20份，益智仁25份，黄芪15份，益母草30份。
3.根据权利要求1或2所述的治疗糖尿病的药物，其特征在于所述治疗糖尿病的药物的剂型为胶囊。
4.权利要求3所述的治疗糖尿病药物的制备方法，其具体加工步骤如下：
A 、按配比称取上述各原材料，加４倍量的水，浸泡４０分钟后，煎煮６０分钟，煎煮液A和药渣A；
Ｂ、向药渣A中加入２倍量的水，煎煮４０分钟，得煎煮液B和药渣B；
Ｃ、合并２次煎煮液，静置12各小时，将上清液过200目筛，得滤液A；
D、将滤液A蒸发至稠膏状，停止加热，喷雾干燥，得干膏饼；
E、将干膏饼粉碎后，过40-80目筛，装入空心胶囊，即可。
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Citations (2)

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Publication number Priority date Publication date Assignee Title
CN105833080A (zh) * 2016-05-05 2016-08-10 成都易胜科生物科技有限公司 一种用于治疗糖尿病的中药组方
CN105999057A (zh) * 2016-05-31 2016-10-12 汤曙光 一种治疗糖尿病的中药

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105833080A (zh) * 2016-05-05 2016-08-10 成都易胜科生物科技有限公司 一种用于治疗糖尿病的中药组方
CN105999057A (zh) * 2016-05-31 2016-10-12 汤曙光 一种治疗糖尿病的中药

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