CN108641262A - 一种隐形眼镜材料及其制备 - Google Patents
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Abstract
本发明公开了一种隐形眼镜材料及其制备。所述隐形眼镜材料包括基体，分散于所述基体中的聚合物纳米胶囊和片状纤维素材料；所述基体为水凝胶，所述聚合物纳米胶囊能够通过化学反应释放氧气。本发明的隐形眼镜材料通过在高透氧性的隐形眼镜材料的基体中增加抗紫外线的片状纤维素材料，使其具有抗紫外性能的同时。并且与添加传统的抗紫外线物质相比，片状纤维素材料具有生物相容性。
Description
技术领域
本发明涉及眼镜技术领域，具体涉及一种隐形眼镜材料及其制备。
背景技术
随着人们对于美丽的追求，越来越多的近视患者会选择佩戴隐形眼镜。隐形眼镜基本上分类为软质型和硬质型眼镜。其中，软质隐形眼镜通常分为水凝胶隐形眼镜和非水凝胶隐形眼镜。常规的软质水凝胶隐形眼镜通常由亲水性单体(例如甲基丙烯酸羟基乙酯、N-乙烯基吡咯烷酮等)的共聚物组成，且可通过车床切割方法、旋转浇筑方法、注塑成型方法或其组合，之后通过在生理盐水和/或磷酸盐缓冲溶液中进行溶胀处理以获得含水量20％-80％(质量百分比)的眼镜而制成。
随着人们安全意识的增强，对于隐形眼镜的性能要求也越来越高，例如透氧性、抗紫外性、生物相容性。
发明内容
基于以上背景技术，本发明提供一种隐形眼镜材料及其制备，通过在高透氧性的隐形眼镜材料的基体中增加抗紫外线的片状纤维素材料，使其具有抗紫外性能的同时。并且与添加传统的抗紫外线物质相比，片状纤维素材料具有生物相容性。
为了实现上述目的，本发明采用以下技术方案：
一种隐形眼镜材料，包括基体，分散于所述基体中的聚合物纳米胶囊和片状纤维素材料；所述基体为水凝胶，所述聚合物纳米胶囊能够通过化学反应释放氧气。
优选地，所述聚合物纳米胶囊包括过氧化氢溶液及包裹所述过氧化氢溶液的壁材。
更优选地，所述壁材选自甲壳素、聚乳酸羟基乙酸共聚物、海藻酸钠或明胶。所选壁材为可分解的高分子，壁材在基体中缓慢分解而释放出过氧化氢溶液，过氧化氢自行分解并释放出氧气和水，提高隐形眼镜的透氧性。
优选地，所述片状纤维素材料粒径大小为10-40微米，厚度1-5微米。所述片状纤维素材料能够阻断UVA 320-400 nm、UVB 280-320 nm范围紫外线的透过，使得隐形眼镜具有抗紫外线性能。
本发明还提供上述隐形眼镜材料的制备方法，包括以下步骤：
将片状纤维素材料、聚合物纳米胶囊、亲水性单体、水合聚合物、光引发剂以及交联剂混合，在紫外光照射下，亲水性单体和水合聚合物发生聚合反应，形成基体，所述片状纤维素材料和聚合物纳米胶囊分散于所述基体中。
优选地，所述亲水性单体选自N-乙烯基吡咯烷酮、甲基丙烯酸缩水甘油酯或N,N-二甲基丙烯酰胺；所述水合聚合物选自甲基丙烯酸甲酯或甲基丙烯酸羟乙酯。
优选地，所述片状纤维素材料、聚合物纳米胶囊、亲水性单体、水合聚合物、光引发剂以及交联剂的质量比为（0.01-0.05）:（0.001-0.01）: 1 : 1:（0.01-0.1）:（0.001-0.01）。
本发明的有益效果
本发明公开的隐形眼镜材料，通过在高透氧性的隐形眼镜材料的基体中增加抗紫外线的片状纤维素材料，使其具有抗紫外性能的同时。并且与添加传统的抗紫外线物质相比，片状纤维素材料具有生物相容性。
具体实施方式
下面通过实施例对本发明进行具体描述，有必要在此指出的是本实施例只用于对本发明进行进一步说明，不能理解为对本发明保护范围的限制，该领域的技术熟练人员可以根据以上发明的内容做出一些非本质的改进和调整。在不冲突的情况下，本发明中的实施例及实施例中的特征可以相互组合。以下实施例中的光引发剂为 Irgacure-1173，交联剂为二甲基丙烯酸乙二醇酯。
实施案例1
将片状纤维素材料、聚合物纳米胶囊、N-乙烯基吡咯烷酮、甲基丙烯酸甲酯、光引发剂以及交联剂按照质量比（0.01 : 0.01 : 1 : 1: 0.01: 0.001）混合，在紫外光照射下，N-乙烯基吡咯烷酮和甲基丙烯酸甲酯在光引发剂和交联剂的作用下发生聚合反应，形成水凝胶基体，所述片状纤维素材料和聚合物纳米胶囊分散于所述基体中。紫外线透过率为57%。
实施案例2
将片状纤维素材料、聚合物纳米胶囊、N-乙烯基吡咯烷酮、甲基丙烯酸甲酯、光引发剂以及交联剂按照质量比（0.02 : 0.005 : 1 : 1: 0.05: 0.005）混合，在紫外光照射下，N-乙烯基吡咯烷酮和甲基丙烯酸甲酯在光引发剂和交联剂的作用下发生聚合反应，形成水凝胶基体，所述片状纤维素材料和聚合物纳米胶囊分散于所述基体中。紫外线透过率为：53%。
实施案例3
将片状纤维素材料、聚合物纳米胶囊、甲基丙烯酸缩水甘油酯、甲基丙烯酸甲酯、光引发剂以及交联剂按照质量比（0.02 : 0.005 : 1 : 1: 0.05: 0.005）混合，在紫外光照射下，N-乙烯基吡咯烷酮和甲基丙烯酸甲酯在光引发剂和交联剂的作用下发生聚合反应，形成水凝胶基体，所述片状纤维素材料和聚合物纳米胶囊分散于所述基体中。紫外线透过率为54%。
实施案例4
将片状纤维素材料、聚合物纳米胶囊、甲基丙烯酸缩水甘油酯、甲基丙烯酸羟乙酯、光引发剂以及交联剂按照质量比（0.02 : 0.005 : 1 : 1: 0.05: 0.005）混合，在紫外光照射下，N-乙烯基吡咯烷酮和甲基丙烯酸甲酯在光引发剂和交联剂的作用下发生聚合反应，形成水凝胶基体，所述片状纤维素材料和聚合物纳米胶囊分散于所述基体中。紫外线透过率为52%。
实施案例5
将片状纤维素材料、聚合物纳米胶囊、N,N-二甲基丙烯酰胺、甲基丙烯酸羟乙酯、光引发剂以及交联剂按照质量比（0.03 : 0.001 : 1 : 1: 0.1: 0.01）混合，在紫外光照射下，N-乙烯基吡咯烷酮和甲基丙烯酸甲酯在光引发剂和交联剂的作用下发生聚合反应，形成水凝胶基体，所述片状纤维素材料和聚合物纳米胶囊分散于所述基体中。紫外线透过率为42%。
实施案例6
将片状纤维素材料、聚合物纳米胶囊、N,N-二甲基丙烯酰胺、甲基丙烯酸羟乙酯、光引发剂以及交联剂按照质量比（0.04 : 0.001 : 1 : 1: 0.1: 0.01）混合，在紫外光照射下，N-乙烯基吡咯烷酮和甲基丙烯酸甲酯在光引发剂和交联剂的作用下发生聚合反应，形成水凝胶基体，所述片状纤维素材料和聚合物纳米胶囊分散于所述基体中。紫外线透过率为30%。
实施案例7
将片状纤维素材料、聚合物纳米胶囊、N,N-二甲基丙烯酰胺、甲基丙烯酸羟乙酯、光引发剂以及交联剂按照质量比（0.05 : 0.001 : 1 : 1: 0.1: 0.01）混合，在紫外光照射下，N-乙烯基吡咯烷酮和甲基丙烯酸甲酯在光引发剂和交联剂的作用下发生聚合反应，形成水凝胶基体，所述片状纤维素材料和聚合物纳米胶囊分散于所述基体中。紫外线透过率为25%。
对比案例1
将聚合物纳米胶囊、N,N-二甲基丙烯酰胺、甲基丙烯酸羟乙酯、光引发剂以及交联剂按照质量比（0.001 : 1 : 1: 0.1: 0.01）混合，在紫外光照射下，N-乙烯基吡咯烷酮和甲基丙烯酸甲酯在光引发剂和交联剂的作用下发生聚合反应，形成水凝胶基体，所述聚合物纳米胶囊分散于所述基体中。紫外线透过率为82%。由此数据可看出，由于加入的片状纤维素材料能够阻断UVA 320-400 nm、UVB 280-320 nm范围紫外线的透过，使得隐形眼镜具有抗紫外线性能。
由以上实施例1-7所得隐形眼镜材料的紫外线透过率数据可看出，随着片状纤维素材料的含量的升高，抗紫外线的效果越好，但是从可见光的透光性来看，当片状纤维素材料的质量比达到0.03时，会逐渐影响隐形眼镜的清晰度，因此片状纤维素材料的质量比优选地为0.01-0.03。
Claims (7)
1.一种隐形眼镜材料，其特征在于，包括基体，分散于所述基体中的聚合物纳米胶囊和片状纤维素材料；所述基体为水凝胶，所述聚合物纳米胶囊能够通过化学反应释放氧气。
2.根据权利要求1所述的隐形眼镜材料，其特征在于，所述聚合物纳米胶囊包括过氧化氢溶液及包裹所述过氧化氢溶液的壁材。
3.根据权利要求2所述的隐形眼镜材料，其特征在于，所述壁材选自甲壳素、聚乳酸羟基乙酸共聚物、海藻酸钠或明胶。
4.根据权利要求1所述的隐形眼镜材料，其特征在于，所述片状纤维素材料粒径大小为10-40微米，厚度1-5微米。
5.一种权利要求1-4任一所述的隐形眼镜材料的制备方法，其特征在于，包括以下步骤：
将片状纤维素材料、聚合物纳米胶囊、亲水性单体、水合聚合物、光引发剂以及交联剂混合，在紫外光照射下，亲水性单体和水合聚合物发生聚合反应，形成基体，所述片状纤维素材料和聚合物纳米胶囊分散于所述基体中。
6.根据权利要求5所述的制备方法，其特征在于，所述亲水性单体选自N-乙烯基吡咯烷酮、甲基丙烯酸缩水甘油酯或N,N-二甲基丙烯酰胺；所述水合聚合物选自甲基丙烯酸甲酯或甲基丙烯酸羟乙酯。
7.根据权利要求5所述的制备方法，其特征在于，所述片状纤维素材料、聚合物纳米胶囊、亲水性单体、水合聚合物、光引发剂以及交联剂的质量比为（0.01-0.05）:（0.001-0.01）: 1 : 1:（0.01-0.1）:（0.001-0.01）。
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| CN104974357A (zh) * | 2014-04-10 | 2015-10-14 | 中国科学院理化技术研究所 | 抗紫外线片状纤维素材料及其制备方法和应用 |
| CN106773120A (zh) * | 2015-11-25 | 2017-05-31 | 鸿富锦精密工业（深圳）有限公司 | 隐形眼镜镜片材料及隐形眼镜镜片 |
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| CN106773120A (zh) * | 2015-11-25 | 2017-05-31 | 鸿富锦精密工业（深圳）有限公司 | 隐形眼镜镜片材料及隐形眼镜镜片 |
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| CN112316219A (zh) * | 2020-09-29 | 2021-02-05 | 浙江大学 | 一种防粘连水凝胶-蚕丝支架复合膜及其制备与应用 |
| CN112316219B (zh) * | 2020-09-29 | 2022-05-10 | 浙江大学 | 一种防粘连水凝胶-蚕丝支架复合膜及其制备与应用 |
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