CN108634014A - A kind of preparation method of prevention of cardiovascular disease tea oil - Google Patents
A kind of preparation method of prevention of cardiovascular disease tea oil Download PDFInfo
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- A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
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Abstract
A kind of preparation method of prevention of cardiovascular disease tea oil disclosed by the invention, is related to biological medicine and food processing technology field, is prepared by the raw material of following parts by weight：The white skin powder of tea oil 50 65, rosemary powder 38, garlic powder 6 10, fish oil 38, cassia seed powder 37, lecithin 4 10, chrysanthemum powder 25, lycopene 0.01 1, shaddock 24；Its preparation process is as follows：A, it crushes；B, first amalgamation；C, two are just mixed；D, three are just mixed；E, total amalgamation；F, two are always mixed；G, three are always mixed；H, alcohol is handled；I, water process；J, it filters.Have the characteristics that nutritive value it is higher, can prevention of cardiovascular it is sick, it is edible to be suitable for angiocardiopathy and the middle-aged and the old, can be not only used for preventing, it can also be used to treat.
Description
Technical field
The present invention relates to biological medicine and food processing technology field, especially a kind of preparation of prevention of cardiovascular disease tea oil
Method.
Background technology
Angiocardiopathy, also known as circulation system disease are a series of diseases for being related to the circulatory system, be subdivided into it is acute and
It is chronic, it is typically related with artery sclerosis.Common disease has hypertension, coronary heart disease (angina pectoris, myocardial infarction), hyperlipidemia
Deng.
Currently, traditional Chinese medicine prevention cardiovascular disease research obtains many-sided progress, as activating blood and resolving stasis and treating coronary disease and angina pectoris,
Qi and activate blood circulation or invigorating Qi treatment acute myocardial infarction or cardiac insufficiency, the supplementing qi and invigorating vasculum temperature sun treatment Retarder theory rhythm of the heart
Establish the yang function poison treatment vital myocarditis, vital energy regualting and blood circulation-promoting of not normal, QI invigorating prevents restenosis etc. after coronary heart disease interventional therapy, all aobvious
It is shown with effect certainly.It is cardiovascular in prevention although it is not so good as chemical synthetic drug for the action intensity of some pathology link
In terms of many diseases of system, certain advantage is also shown.
Chinese patent (number of patent application 201210242609.0) disclosed " a kind of anti-aging, the cardiovascular flexible glue of protection
Capsule and preparation method thereof ", feature are：Content is weighed by weight percentage：Seabuckthorm Seed Oil 40%~60%, lecithin 1%~
3%, vitamin e1 %~3%, lycopene 4%~8%, propolis 5%~9%, pumpkin seed oil 20%~30%, collagen
6%~10%, mixing, grinding, degassing；Gelatin, water, glycerine, temperature increasing for melting materials are weighed in 100: 100: 40 ratios, degassing obtains soft
Capsule body filtrate；By weight by filtrate and content：Pelleting in 1: 2~3 ratio feeding pellet press, then dry through sizing,
Wash ball, choosing pick, pack, obtain finished product.Component synergistic effect selected by the invention, effectively improves body immunity.Its dosage section
It learns, has the function of beauty, anti-aging, protection angiocarpy, supplementing the kidney to control the nocturnal；Preparation method technique closes A reasons, and operability is strong, easily
It accomplishes scale production.
" a kind of tune helping cardiovascular health disclosed in another Chinese patent (number of patent application 201610610450.1)
And vegetable oil powder ", it is made of following raw material：Soybean 300-320, olive 200-230, deep sea fish oil 20-25, hundred
Close essential oil 0.2-0.5, hawthorn 35-40, new lotus leaf 10-15, Radix Salviae Miltiorrhizae 5-6, Radix Notoginseng 4-5, borneol 2-3, ginkgo leaf 5-6, prepared rehmannia root
5-6, Fructus Corni 4-5 etc.；The present invention is simple and practicable, is suitble to large-scale production, deep sea fish oil is added on formula, has
Have and protect cardiovascular effect well, vitamin E, lecithin are added in grease simultaneously, it is anti-oxidant that collaboration can be played
Effect, oxidation resistance is strong, avoids the use of preservative, and by powdered oil, can preferably store, and transporter
Just, application range is more extensive.
Invention content
A kind of preparation side of the purpose of the present invention is to provide nutritive values tea oil that is higher, being capable of prevention of cardiovascular disease
Method.
To achieve the above object, the technical measures that the present invention is taken are to invent a kind of preparation of prevention of cardiovascular disease tea oil
Method is prepared by the raw material of following parts by weight：
Tea oil 50-65 rosemary powder 3-8 garlic powders 6-10
Fish oil 3-8 cassia seed powder 3-7 lecithin 4-10
The white skin powder 2-4 of chrysanthemum powder 2-5 lycopene 0.01-1 shaddocks；
Its preparation process is as follows：
A, it crushes：Rosemary powder, garlic powder, cassia seed powder, chrysanthemum powder, lycopene and the white skin powder of shaddock are passed through respectively
Ultra micro is processed into the fine powder of 200 mesh or more, obtains rosemary fine powder, garlic fine powder, cassia seed fine powder, chrysanthemum fine powder, lycopene
The white skin fine powder of fine powder, shaddock；
B, first amalgamation：The 1/3 of above-mentioned raw materials tea oil weight and rosemary fine powder, lycopene fine powder are mixed together, so
It is placed in ultrasonic container, in 60-70 DEG C, frequency to be ultrasonically treated 3.5-6.0h under conditions of 200-300Hz, filters (aperture
It is 10-30 microns), tea oil one must be mixed；
C, two are just mixed：Cassia seed fine powder is mixed with garlic fine powder, at the same be added account for cassia seed fine powder weight 25-35%,
The silica white of 100 mesh stirs evenly, then the 1/3 of above-mentioned raw materials tea oil weight and the 1/3 of above-mentioned raw materials lecithin weight are added together
Wherein, it stirs evenly, is then heated to 150-180 DEG C, constant temperature stir process 2.5-5.5h, the rate of heat addition is 5-8 DEG C/min, filtering
(aperture is 1-5 microns), must mix tea oil two；
D, three are just mixed：Together by the white skin fine powder of shaddock, the 1/3 of above-mentioned raw materials lecithin weight and remaining raw material tea oil
Mixing, is placed in water-bath, the constant temperature stir process 3.0-5.0h at 60-70 DEG C, and filtering (aperture is 0.5-1 microns) must mix
Tea oil three；
E, total amalgamation：Tea oil one will be mixed and mix two mixing of tea oil, and added and account for former tea oil weight (i.e.：Above-mentioned raw materials
The 2/3 of tea oil weight) 15-35% neutral active charcoal particle (grain size 0.05-0.15cm), and be heated to 100-150 DEG C and (add
Hot rate is 3-5 DEG C/min), stir process 10-15h, stir speed (S.S.) 60-100r/min, (aperture is that 0.1-0.2 is micro- for filtering
Rice), obtain activated carbon processing mixing tea oil；Into activated carbon processing mixing tea oil, slowly (speed of addition is warm water total amount again
2-3 times of weight, 40-50 DEG C of warm water 5-10%/min) is added, side edged stirs, stir speed (S.S.) 50-60r/min, stands, divides
Layer, filtering (aperture is 0.1-0.2 microns), collect the tea oil on upper layer, obtain total amalgamation tea oil, spare；
F, two are always mixed：Total amalgamation tea oil is placed in oscillator, the oscillation treatment 1.5- in the case where frequency is 800-1000Hz
During which 3.5h is put into after mixing chrysanthemum fine powder and remaining raw material lecithin, thereafter, filtering obtains and always mixes two tea oil；
G, three are always mixed：Total mixed two tea oil are heated to 70-90 DEG C, the rate of heat addition is 1-3 DEG C/min, adds and accounts for former tea oil
Weight is (i.e.：The 2/3 of above-mentioned raw materials tea oil weight) 10-18%, 100 mesh silica decoloration sand, constant temperature stir process 1.5-2.5h,
After cooled to room temperature, filters (aperture 10-20nm), obtain decoloration tea oil；It then will mixing tea oil three, fish oil and decoloration tea
Oily mixing, obtains and always mixes tea oil；
H, alcohol is handled：Total mixing tea oil is put into 2-3 weight, in the edible ethanol solution that volumetric concentration is 20-35%,
Stir process 1.0-1.5h at 45-65 DEG C, it is quiet to put to room temperature, layering, the ethanol solution of lower layer is filtered out, alcohol treatment mixing is obtained
Tea oil；
I, water process：Alcohol treatment is mixed tea oil to put into the boiling water of identical weight, stir process 10-25min is quiet to put
To room temperature, layering, the water of lower layer is filtered out, obtains water process mixing tea oil；
J, it filters：Water process is mixed into the tea oil ultrafiltration membrane that via hole diameter is 10-15nm in the case where pressure is 1.5-2.5MPa dress
Filtering is set, collects filtering fluid to get prevention of cardiovascular disease tea oil.
Its technical solution one optimized is prepared by the raw material of following parts by weight：
50 rosemary powder of tea oil, 3 garlic powder 10
8 cassia seed powder of fish oil, 7 lecithin 4
The white skin powder of 5 lycopene of chrysanthemum powder, 0.01 shaddock 2.
The technical solution that it optimizes by the raw material of following parts by weight second is that be prepared：
65 rosemary powder of tea oil, 8 garlic powder 6
3 cassia seed powder of fish oil, 3 lecithin 10
The white skin powder of 2 lycopene of chrysanthemum powder, 1 shaddock 4.
Its technical solution three optimized is prepared by the raw material of following parts by weight：
58 rosemary powder of tea oil, 6 garlic powder 8
6 cassia seed powder of fish oil, 5 lecithin 7
The white skin powder of 4 lycopene of chrysanthemum powder, 0.5 shaddock 3.
The rosemary powder is commercially available Rosmarinus officinalis extract, can also be to be prepared as follows：Fan is changed
Spiceleaf raw material cleans, dries in the shade or is dried to that moisture is less than 8%, then puts into the petroleum ether of 1-3 times of weight, impregnates at normal temperatures
1.5-3.0h is handled, is filtered (100-160 mesh), then rosemary leave identical weight, 40-60 DEG C of warm water are washed 2-3 times, is filtered
Solid carbon dioxide point, is transferred in baking oven, and moisture is dried at 50-65 DEG C and is less than 5%, is reprocessed into rosemary leave powder more than 40 mesh
End；2-4 times of weight is added into rosemary leave powder again, the edible ethanol that volumetric concentration is 90% or more, impregnates at normal temperatures
3-5h is handled, is filtered (being filtered with Medium speed filter paper), rosemary ethyl alcohol soak is collected；Rosemary ethyl alcohol soak is transferred to drop
Rosemary ethyl alcohol of the concentration of alcohol less than 20% is concentrated into membrane concentrator, at being 40-60 DEG C in pressure 5-10KPa, temperature to soak
Steep concentrate；Rosemary ethyl alcohol immersion concentrate is transferred in freezer again, 4-10 DEG C it is quiet put 2-4h, filtering is (micro- with 8-12
The membrane filtration of rice), the precipitation of precipitation is collected, then precipitation is put into baking oven, dries to moisture and is less than at 50-65 DEG C
5%, obtain rosemary dry powder；Again by rosemary dry powder in the case where pressure is 0.5-1.75MPa, temperature is 40-55 DEG C, through overcritical dress
Extraction is set, collects light yellow extract to get rosemary powder.
The garlic powder is crushed after drying garlic, can also be to be prepared as follows：By garlic
Seed is cleaned, and moisture is dried at 40-60 DEG C and is less than 12%, the garlic of 40 mesh or more is then processed into, then by garlic
Powder is mixed together with the dry shredded ginger for accounting for garlic weight 3-5%, is stir-fried back and forth 5-10min through small fire, is pulled out, wait for nature
It is cooled to room temperature and removes dry shredded ginger, obtain processing garlic；Processing garlic is put into 1-3 times of weight, volumetric concentration again
In the edible ethanol of 40-50%, the immersion treatment 1.0-2.5h at 50-65 DEG C filters (being filtered with Medium speed filter paper), obtains garlic second
Alcohol soak；Garlic ethyl alcohol soak is transferred in falling film condenser, is concentrated at being 40-60 DEG C in pressure 5-10KPa, temperature
To no alcohol, obtains garlic ethyl alcohol and impregnate concentrate；It is spray-dried to get garlic powder that garlic ethyl alcohol is impregnated into concentrate again.
The cassia seed powder is commercially available cassia seed extract, can also be to be prepared as follows：By Cassia
Son is cleaned, and is dried or is dried to moisture and be less than 8%, is then processed into the cassia seed coarse powder of 20-40 mesh；Cassia seed coarse powder is thrown again
Enter 1-2 times of weight, in weak base (sodium carbonate or sodium bicarbonate) solution that mass fraction is 1.5-3.5%, is impregnated at 40-50 DEG C
20-45min, filtering obtain processing cassia seed powder then with water washing is purified 1-2 times；Cassia seed powder will be handled again and accounts for former Cassia
Sub- weight 10-20%, the mixing of processed silica decoloration sand, moisture is dried at 40-60 DEG C and is less than 5%, obtains dry Cassia
Sub- mixture；Dry cassia seed mixture is processed into the cassia seed fines of 120 mesh or more through homogenizer, then with 2-3 times of weight, body
The edible ethanol solution of a concentration of 50-70% of product immersion treatment 1.0-2.5h at 50-65 DEG C, filtering obtain the leaching of cassia seed ethyl alcohol
Steep liquid；Cassia seed ethyl alcohol soak is transferred to shady place, (the decline of concentration of alcohol when concentration of alcohol deteriorates to less than 30%
For natural volatilization), remaining cassia seed ethanol solution is collected in filtering；Cassia seed ethanol solution is transferred to falling film condenser again
In, it is concentrated into no alcohol at being 40-60 DEG C in pressure 5-10KPa, temperature, obtains cassia seed ethyl alcohol concentrate；Then by cassia seed second
Alcohol concentrate is naturally quiet to put 5-10h, and the cassia seed precipitation of precipitation is collected in filtering；Cassia seed is deposited in 50-65 DEG C of drying to water
Divide and be less than 5%, crushes to get cassia seed powder.
The chrysanthemum powder is commercially available chrysanthemum extract, can also be to be prepared as follows：By chrysanthemum medicine materical crude slice
It puts into the purified water of 2-4 times of weight, 10-25min is boiled in boiling, is filtered, is obtained water cooking liquid；Again by water cooking liquid it is spray-dried to get
Chrysanthemum powder (chrysanthemum flavones content is 50% or more).
The white skin powder of the shaddock is formed by the white skin crushed after being dried of shaddock, can also be prepared as follows and
At：The white skin of shaddock is put into together with the pure vinegar for accounting for the white tare weight amount 50-70% of shaddock in frying pan, 10- is fried back and forth with small fire
18min pulls out, drains, place into boiling water, stir 5-8min back and forth, pulls out, must handle the white skin of shaddock；Shaddock will be handled again
White skin is transferred in baking oven, and moisture is dried at 40-60 DEG C and is less than 10%, at the beginning of being then processed into the white skin of shaddock of 40 mesh or more
Powder；Powder at the beginning of the white skin of shaddock is put into 2-3 times of weight, volumetric concentration in 70% or more edible ethanol, to impregnate 2-4 under room temperature again
It, filtering obtains ethyl alcohol soak；Ethyl alcohol soak is transferred in falling film condenser again, in pressure 5-10KPa, temperature 40-60
It is 40-45% that concentration of alcohol is concentrated at DEG C, obtains ethyl alcohol concentrate；Ethyl alcohol concentrate is crossed into column, flow velocity 3.2- through mixed column again
3.8L/h collects upper prop liquid；Upper prop liquid is transferred in falling film condenser again, it is dense at pressure 5-10KPa, 60-70 DEG C of temperature
It is 2.2-3.4mg/ml to be reduced to solid content, obtains concentrate；Concentrate is put into freezer again, 5-10h is placed at 0-4 DEG C,
Precipitation is collected in filtering；It will be deposited in 50-65 DEG C of drying to moisture again and be less than 5%, crush to get the white skin powder of shaddock.
The mixed column is by 200 mesh silica decoloration sand and 40-60 mesh quartz sands by 3：1 ratio Hybrid assembling forms.
The tea oil refers to the edible camellia oil for meeting GB/T11765-2003 national standards.
The lycopene refers to the lycopene for meeting national GB/T22249-2008 examination criterias.
The fish oil refers to the fish oil for meeting SC/T3502-2016 examination criterias.
The lecithin refers to commercially available edible lecithin.
The prevention of cardiovascular disease tea oil of the present invention, primary raw material includes tea oil, rosemary powder, garlic powder, fish oil, Cassia
Sub- powder, lecithin, chrysanthemum powder, lycopene and the white skin powder of shaddock.
Tea oil (Camellia oleifera Abel) belongs to Theaceae, is the main and distinctive woody edible oil in China.
The comprehensive utilization value of tea oil is very high, containing abundant unsaturated fatty acid, monounsaturated fatty acids, vitamin E, squalene,
The bioactive substances such as tea polyphenols.Monounsaturated fatty acids can improve blood antioxidant ability, reduce cholesterol, prevent heart and brain blood
The generation of pipe disease, moreover it is possible to reduce the appearance machine of such as insulin resistance diabetes etc disease because of caused by metabolism disorder
Rate, unsaturated fatty acid have not polyester " characteristic, not only itself is not in internal organ and subcutaneous deposition, but also fat can be prevented heavy
Product, can be to avoid getting fat, medically, and tea oil is used for auxiliary treatment obesity, is a kind of healthy edible of " eat oil be not afraid of fat "
Oil.
Rosemary powder is extracted by rosemary (Rosmarinus officinalis), has raising anti-oxidant in vivo
Enzymatic activity, anti-lipid peroxidation, the effect of anti-aging.
Garlic powder is prepared by garlic (Allium Sativum L.), has clear pest, removing toxic substances, work(promoting blood circulation and removing blood stasis
Can, can reducing blood lipid, blood pressure lowering, it is hypoglycemic also have anti-platelet aggregation, prevention of arterial atherosis, cardioprotection is from invading
It attacks, reduces Coronary Atherosclerotic Plaque, antithrombotic etc..
The English name of fish oil is Fats and Glyceridic oils, and No. CAS is 8016-13-5, is derived from big
Whole oily substances in type marine fishes body, main component are Omega-3 aliphatic acid (including DHA and EPA), are that one kind is more
First unsaturated fatty acid can reduce inflammatory response, reduce blood fat, prevent cardiovascular disease.
Cassia seed powder is prepared by cassia seed (CatsiatoraLinn), has the function of clearing liver and improving vision, defaecation.It is main
Control the diseases such as hypertension, headache, dizziness, acute conjunctivitis, ulcer of the cornea, glaucoma, carbuncle furuncle sore.It is made tea with its leaf, person in middle and old age
People's long-term drinking can make blood pressure normal, free movement of the bowels.
Lecithin (Lecithin) has the function of emulsification, cuts grease, can promote blood circulation, improves serum lipids,
Peroxide is removed, Blood Cholesterol and neutral fat content is made to reduce, the residence time of fatty wall in the blood vessels is reduced, promotees
Into the dissipation of atherosis spot, the blood vessel internal membrane damage caused by cholesterol is prevented.
Chrysanthemum powder is by the drying head of feverfew chrysanthemum [Dendranthema morifolium (Ramat.) Tzvel.]
The substance (ChrysanthemummorifoliumRamat.) of inflorescence extraction, active ingredient is chrysanthemum flavones, has heat-clearing solution
Malicious fall fire, flat liver improving eyesight is anti-oxidant, anti-aging and other effects.
Lycopene (lycopene) is the primary pigments of mature tomato, is a kind of oxygen-free carotenoid.It has
Anti-oxidant, inhibition mutation reduces nucleic acid damaging, reduces the plurality of health care functions such as angiocardiopathy and pre- anti-cancer.
The white skin powder of shaddock is that the white skin after the bluish yellow skin for removing surface by shaddock (Citrus maxima) skin is prepared,
With hypoglycemic, reducing blood lipid, weight-reducing, skin-care and beautifying and other effects, there is auxiliary to control the diseases such as hypertension, diabetes, vascular sclerosis
Treatment acts on.
The prevention of cardiovascular disease tea oil prepared by above-mentioned many raw materials, containing there are many decompression, lipid-loweringing, anti-oxidant, the protection hearts
The substance of blood vessel and the active material beneficial to human body, thus, it is possible to effectively prevent the generation of angiocardiopathy.
Following table 1 is the effective ingredient detection data of the prevention of cardiovascular disease tea oil of the present invention：
The effective ingredient detection table (content of 100g) of the prevention of cardiovascular disease tea oil of 1 present invention of table
It can be seen that the prevention of cardiovascular disease tea oil of the present invention from upper table data, not only contain abundant single unsaturated lipid
Fat acid and unsaturated fatty acid, also contain the benefit materials such as more polysaccharide, flavonoids.
30 hypertensive patients were once carried out drop test by the prevention of cardiovascular disease tea oil of the present invention：
1, diagnosis basis
With the publication of Hunan science tech publishing house, the ugly husband of journey and Wang Zhonglin chief editors《The practical internal medicine handbook (second edition》
(in March, 2004 the 17th printing of second edition) is diagnostic criteria, using clinical manifestation and hospital inspection data as foundation, in conjunction with prevalence
Sick data is referred to, and other diseases are removed.
2, general information
30 hypertensive patients for meeting above-mentioned diagnostic criteria are divided by blood pressure level, wherein：1 grade of hypertensive patient 12
Example, 2 grades of hypertensive patients 8,3 grades of hypertensive patients 10；
All patients are randomly divided into test group 16 and control group 14, wherein：In test group, male 10, female 6,
Age 34-60 Sui, average age 44 years old, sick time -2 years 2 months, 1 grade of hypertensive patient 6,2 grades of hypertensive patients 4,
3 grades of hypertensive patients 6；In control group, male 8, female 6, age 40-55 Sui, average age 48 years old, sick time 8 months-
2 years, 1 grade of hypertensive patient 6,2 grades of hypertensive patients 4,3 grades of hypertensive patients 4.
3, test method
On the basis of original takes antihypertensive drugs, after on-test, reduces original within every 2 months and take antihypertensive drugs 1/3
Quantity cuts out antihypertensive drugs until after 6 months.
(1), test group：
The edible prevention of cardiovascular disease tea oil being prepared by the raw material of following parts by weight is (i.e.：It is subsequent
Embodiment 3)：
58 rosemary powder of tea oil, 6 garlic powder 8
6 cassia seed powder of fish oil, 5 lecithin 7
The white skin powder of 4 lycopene of chrysanthemum powder, 0.5 shaddock 3.
Eating method：During experiment, had a meal dish type and quantity all according to it is normal when it is the same, difference
It is in and is cooked in all prevention of cardiovascular disease tea oil using the present invention.
(2), control group：
During experimental control, had a meal dish type and quantity all according to it is normal when it is the same, cook oil used
Fat is common tea oil.
4, curative effect determinate standard
With reference to as defined in the Ministry of Public Health《Clinical Researches of New Drugs guideline draft》Middle hypertension criterion of therapeutical effect judgement.
It is effective:Diastole drops >=10mmHg is simultaneously down to normal or declines 20mmHg or more, headache, dizziness, palpitaition, weak
Etc. clinical symptoms disappear or it is substantially reduced；
Effectively:Diastole drops<10mmHg, but be reduced to normal or decline 10~19mmHg, or shrink drops>
30mmHg；
In vain:Above two standards are not reached.
5, test effect
By experiment in 12 months, check-up through statistical means data formed below table：
It has been shown that, prevention of cardiovascular disease tea oil of the invention there is good curative effect to hypertension, always by above-mentioned statistical data
Effective percentage is up to 81.25%.
Specific implementation mode
With reference to embodiments, the present invention is further illustrated.Following explanation is but this hair in a manner of enumerating
Bright protection domain is not limited thereto.
Embodiment 1：
The prevention of cardiovascular disease tea oil of the present embodiment, preparation process are as follows：
One, pretreatment of raw material：
1, prepared by rosemary powder：Rosemary leave raw material is cleaned, dried in the shade or be dried to that moisture is less than 8%, then puts into 2 times
In the petroleum ether (boiling point be 40-50 DEG C) of weight, immersion treatment 2.0h, is filtered (120 mesh sieve) at normal temperatures, then by rosemary leave
It is washed 2 times with identical weight, 50 DEG C of warm water, is filtered dry moisture, is transferred in baking oven, moisture is dried at 55 DEG C and is less than 5%,
Reprocess into the rosemary leave powder of 40 mesh or more；Again into rosemary leave powder be added 3 times of weight, volumetric concentration be 90% with
On edible ethanol, immersion treatment 4h at normal temperatures filters (being filtered with Medium speed filter paper), collects rosemary ethyl alcohol soak；It will
Rosemary ethyl alcohol soak is transferred in falling film condenser, and being concentrated into concentration of alcohol at being 50 DEG C in pressure 8KPa, temperature is less than
20% rosemary ethyl alcohol impregnates concentrate；Again by rosemary ethyl alcohol immersion concentrate be transferred in freezer, 6 DEG C it is quiet put 3h,
Filtering (membrane filtration for using 8-12 microns), collects the precipitation of precipitation, then precipitation is put into baking oven, dried extremely at 55 DEG C
Moisture is less than 5%, obtains rosemary dry powder；Again by rosemary dry powder in the case where pressure is 1.0MPa, temperature is 48 DEG C, through overcritical dress
Extraction is set, collects light yellow extract to get rosemary powder.
2, prepared by garlic powder：It is cleaned by full grains, without mildew and rot Garlic Seeds, being dried to moisture at 50 DEG C is less than
12%, it is then processed into the garlic of 40 mesh or more, then by garlic and the dry shredded ginger for accounting for garlic weight 4%
It is mixed together, stir-fries 8min, pull out back and forth through small fire, wait for that nature is cooled to room temperature and remove dry shredded ginger, obtain processing garlic；
Garlic will be handled again to put into the edible ethanol of 2 times of weight, volumetric concentration 45%, immersion treatment 1.8h, mistake at 55 DEG C
It filters (being filtered with Medium speed filter paper), obtains garlic ethyl alcohol soak；Garlic ethyl alcohol soak is transferred in falling film condenser, in pressure
8KPa, temperature are to be concentrated into no alcohol at 50 DEG C, obtain garlic ethyl alcohol and impregnate concentrate；Garlic ethyl alcohol is impregnated into concentrate through spraying again
Drying is to get garlic powder.
3, prepared by cassia seed powder：Cassia seed is cleaned, dries or is dried to moisture and be less than 8%, be then processed into 30 purposes
Cassia seed coarse powder；Again by cassia seed coarse powder put into 2 times of weight, mass fraction be 2.5% weak base (sodium bicarbonate) solution in,
35min is impregnated at 45 DEG C, is filtered, and then with water washing is purified 2 times, obtains processing cassia seed powder；Again cassia seed powder will be handled and accounted for
Former cassia seed weight 15%, the mixing of processed silica decoloration sand, moisture is dried at 50 DEG C and is less than 5%, obtains dry Cassia
Sub- mixture；Dry cassia seed mixture is processed into the cassia seed fines of 120 mesh or more through homogenizer, then with 3 times of weight, volumes
A concentration of 60% edible ethanol solution immersion treatment 1.8h at 55 DEG C, filtering, obtains cassia seed ethyl alcohol soak；By cassia seed
Ethyl alcohol soak is transferred to shady place, when concentration of alcohol deteriorates to less than 30% (the falling to nature volatilization of concentration of alcohol),
Filtering, collects remaining cassia seed ethanol solution；Cassia seed ethanol solution is transferred in falling film condenser again, in pressure
8KPa, temperature are to be concentrated into no alcohol at 50 DEG C, obtain cassia seed ethyl alcohol concentrate；Then it puts cassia seed ethyl alcohol concentrate is naturally quiet
The cassia seed precipitation of precipitation is collected in 8h, filtering；Cassia seed is deposited in 55 DEG C of dryings to moisture and is less than 5%, is crushed to get certainly
Pine torch powder.
4, prepared by chrysanthemum powder：Chrysanthemum medicine materical crude slice is put into the purified water of 3 times of weight, 18min is boiled in boiling, is filtered, is obtained water cooking liquid；
It is again that water cooking liquid is spray-dried to get chrysanthemum powder.
5, prepared by the white skin powder of shaddock：By the white skin of shaddock (being that pomelo peel removes remaining white skin after the bluish yellow skin on surface) with account for
The pure vinegar of the white tare weight amount of shaddock 60% is put into frying pan together, is fried 15min back and forth with small fire, is pulled out, drains, place into boiling water
In, 6min is stirred back and forth, is pulled out, and the white skin of shaddock must be handled；The white skin of shaddock will be handled again to be transferred in baking oven, is dried at 50 DEG C
It is less than 10% to moisture, is then processed into the first powder of the white skin of shaddock of 40 mesh or more；Powder at the beginning of the white skin of shaddock is put into 2.5 times of weights again
In amount, the edible ethanol that volumetric concentration is 70% or more, is impregnated 3 days under room temperature, filter, obtain ethyl alcohol soak；Ethyl alcohol is soaked again
Bubble liquid is transferred in falling film condenser, and it is 42% that concentration of alcohol is concentrated under pressure 80KPa, temperature 50 C, obtains ethyl alcohol concentration
Liquid；By ethyl alcohol concentrate, through mixed column, (mixed column is by 200 mesh silica decoloration sand and 50 mesh quartz sands by 3 again：1 ratio
Hybrid assembling forms) column is crossed, flow velocity 3.5L/h collects upper prop liquid；Upper prop liquid is transferred in falling film condenser again, in pressure
It is 2.8mg/ml that solid content is concentrated at 8KPa, 65 DEG C of temperature, obtains concentrate；Concentrate is put into freezer again, at 2 DEG C
8h is placed, precipitation is collected in filtering；It will be deposited in 58 DEG C of dryings to moisture again and be less than 5%, crush to get the white skin powder of shaddock.
6, tea oil takes the edible camellia oil for meeting GB/T11765-2003 national standards.
7, lycopene takes the lycopene for meeting national GB/T22249-2008 examination criterias.
8, fish oil takes the fish oil for meeting SC/T3502-2016 examination criterias.
9, lecithin takes the lecithin that commercially available edible, effective content is more than 95%.
Two, it stocks up：
Take following raw materials according respectively by weight:
50 rosemary powder of tea oil, 3 garlic powder 10
8 cassia seed powder of fish oil, 7 lecithin 4
The white skin powder 2 of 5 lycopene of chrysanthemum powder, 0.01 shaddock, it is spare.
Three, preparation process：
A, it crushes：Rosemary powder, garlic powder, cassia seed powder, chrysanthemum powder, lycopene and the white skin powder of shaddock are passed through respectively
Ultra micro is processed into the fine powder of 200 mesh or more, obtains rosemary fine powder, garlic fine powder, cassia seed fine powder, chrysanthemum fine powder, lycopene
The white skin fine powder of fine powder, shaddock；
B, first amalgamation：The 1/3 of above-mentioned raw materials tea oil weight and rosemary fine powder, lycopene fine powder are mixed together, so
It is placed in ultrasonic container, in 65 DEG C, frequency to be ultrasonically treated 5h under conditions of 250Hz, filtering (aperture is 20 microns) obtains mixed
Close tea oil one；
C, two are just mixed：Cassia seed fine powder is mixed with garlic fine powder, while being added and accounting for cassia seed fine powder weight 30%, 100
Purpose silica white stirs evenly, then it is added in the 1/3 of above-mentioned raw materials tea oil weight and the 1/3 of above-mentioned raw materials lecithin weight together
In, it stirs evenly, is then heated to 160 DEG C, constant temperature stir process 4h, the rate of heat addition is 6 DEG C/min, and filtering (aperture is 3 microns) obtains
Mix tea oil two；
D, three are just mixed：Together by the white skin fine powder of shaddock, the 1/3 of above-mentioned raw materials lecithin weight and remaining raw material tea oil
Mixing, is placed in water-bath, the constant temperature stir process 4h at 65 DEG C, and filtering (aperture is 0.8 micron) must mix tea oil three；
E, total amalgamation：Tea oil one will be mixed and mix two mixing of tea oil, and added and account for former tea oil weight (i.e.：Above-mentioned raw materials
The 2/3 of tea oil weight) 25% neutral active charcoal particle (grain size 0.05-0.15cm), and be heated to 120 DEG C of (rates of heat addition
For 4 DEG C/min), it is mixed to obtain activated carbon processing for stir process 12h, stir speed (S.S.) 80r/min, filtering (aperture is 0.15 micron)
Close tea oil；Into activated carbon processing mixing tea oil, slowly 2.5 times of weights are added in (speed of addition is the 8%/min of warm water total amount) again
Amount, 45 DEG C of warm water, side edged stir, stir speed (S.S.) 55r/min, stand, layering, filter (aperture is 0.15 micron), collect
The tea oil on upper layer obtains total amalgamation tea oil, spare；
F, two are always mixed：Total amalgamation tea oil is placed in oscillator, the oscillation treatment 2.5h in the case where frequency is 900Hz during which will
It is put into after chrysanthemum fine powder and the mixing of remaining raw material lecithin, thereafter, filtering obtains and always mixes two tea oil；
G, three are always mixed：Total mixed two tea oil are heated to 80 DEG C, the rate of heat addition is 2 DEG C/min, adds and accounts for former tea oil weight
(i.e.：The 2/3 of above-mentioned raw materials tea oil weight) 15%, 100 mesh silica decoloration sand, constant temperature stir process 2h naturally cools to room
Wen Hou filters (aperture 15nm), obtains decoloration tea oil；Then tea oil three, fish oil and decoloration tea oil mixing will be mixed, obtains and always mixes
Tea oil；
H, alcohol is handled：Total mixing tea oil is put into 2.5 weight, in the edible ethanol solution that volumetric concentration is 28%, 55
Stir process 1.2h at DEG C, the quiet ethanol solution put to room temperature, be layered, filter out lower layer obtain alcohol treatment mixing tea oil；
I, water process：Alcohol treatment is mixed tea oil to put into the boiling water of identical weight, stir process 10-25min is quiet to put
To room temperature, layering, the water for filtering lower layer, water process mixing tea oil is obtained；
J, it filters：Water process is mixed into the filtering of the tea oil ultra-filtration membrane device that via hole diameter is 12nm in the case where pressure is 2MPa, is received
Collection filtering fluid is to get prevention of cardiovascular disease tea oil.
Embodiment 2：
The prevention of cardiovascular disease tea oil of the present embodiment, preparation process are as follows：
One, pretreatment of raw material：
It is same as Example 1；
Two, it stocks up：
Take following raw materials according respectively by weight:
65 rosemary powder of tea oil, 8 garlic powder 6
3 cassia seed powder of fish oil, 3 lecithin 10
The white skin powder 4 of 2 lycopene of chrysanthemum powder, 1 shaddock, it is spare；
Three, preparation process：
It is same as Example 1.
Embodiment 3：
The prevention of cardiovascular disease tea oil of the present embodiment, preparation process are as follows：
One, pretreatment of raw material：
It is same as Example 1；
Two, it stocks up：
Take following raw materials according respectively by weight:
58 rosemary powder of tea oil, 6 garlic powder 8
6 cassia seed powder of fish oil, 5 lecithin 7
The white skin powder 3 of 4 lycopene of chrysanthemum powder, 0.5 shaddock, it is spare；
Three, preparation process：
It is same as Example 1.
The prevention of cardiovascular disease tea oil of the present invention, is suitable for angiocardiopathy and the middle-aged and the old is edible, can be not only used for preventing,
It can also be used for treating.
Claims (10)
1. a kind of preparation method of prevention of cardiovascular disease tea oil, it is characterised in that be prepared by the raw material of following parts by weight：
Tea oil 50-65 rosemary powder 3-8 garlic powders 6-10
Fish oil 3-8 cassia seed powder 3-7 lecithin 4-10
The white skin powder 2-4 of chrysanthemum powder 2-5 lycopene 0.01-1 shaddocks；
Its preparation process is as follows：
A, it crushes：By rosemary powder, garlic powder, cassia seed powder, chrysanthemum powder, lycopene and the white skin powder of shaddock respectively through ultra micro
Be processed into the fine powder of 200 mesh or more, obtain rosemary fine powder, garlic fine powder, cassia seed fine powder, chrysanthemum fine powder, lycopene fine powder,
The white skin fine powder of shaddock；
B, first amalgamation：The 1/3 of above-mentioned raw materials tea oil weight and rosemary fine powder, lycopene fine powder are mixed together, then set
In ultrasonic container, in 60-70 DEG C, frequency to be ultrasonically treated 3.5-6.0h under conditions of 200-300Hz, filters, obtain tea blend
Oil one；
C, two are just mixed：Cassia seed fine powder is mixed with garlic fine powder, while being added and accounting for cassia seed fine powder weight 25-35%, 100 mesh
Silica white stir evenly, then the 1/3 of above-mentioned raw materials tea oil weight and the 1/3 of above-mentioned raw materials lecithin weight are added thereto together,
It stirs evenly, is then heated to 150-180 DEG C, constant temperature stir process 2.5-5.5h, the rate of heat addition is 5-8 DEG C/min, and filtering must mix
Tea oil two；
D, three are just mixed：The white skin fine powder of shaddock, the 1/3 of above-mentioned raw materials lecithin weight and remaining raw material tea oil are mixed together
It closes, is placed in water-bath, the constant temperature stir process 3.0-5.0h at 60-70 DEG C, filter, tea oil three must be mixed；
E, total amalgamation：Tea oil one will be mixed and mix two mixing of tea oil, and add the neutral active for accounting for former tea oil weight 15-35%
Charcoal particle, and it is heated to 100-150 DEG C, stir process 10-15h, stir speed (S.S.) 60-100r/min, filtering obtain at activated carbon
Reason mixing tea oil；It is slowly added to 2-3 times of weight, 40-50 DEG C of warm water into activated carbon processing mixing tea oil again, side edged stirs,
Stir speed (S.S.) is 50-60r/min, stands, layering, filters, collects the tea oil on upper layer, obtain total amalgamation tea oil, spare；
F, two are always mixed：Total amalgamation tea oil is placed in oscillator, the oscillation treatment 1.5-3.5h in the case where frequency is 800-1000Hz, the phase
Between, it is put into after chrysanthemum fine powder and remaining raw material lecithin are mixed, thereafter, filtering obtains and always mixes two tea oil；
G, three are always mixed：Total mixed two tea oil are heated to 70-90 DEG C, add the silica gel for accounting for former tea oil weight 10-18%, 100 mesh
Decolourize sand, constant temperature stir process 1.5-2.5h, and after cooled to room temperature, filtering obtains decoloration tea oil；Then tea oil will be mixed
Three, fish oil and decoloration tea oil mixing, obtain and always mix tea oil；
H, alcohol is handled：Total mixing tea oil is put into 2-3 weight, in the edible ethanol solution that volumetric concentration is 20-35%, in 45-
Stir process 1.0-1.5h at 65 DEG C, it is quiet to put to room temperature, layering, the ethanol solution of lower layer is filtered out, alcohol treatment tea blend is obtained
Oil；
I, water process：Alcohol treatment is mixed tea oil to put into the boiling water of identical weight, stir process 10-25min is quiet to put to normal
Temperature, layering, filter out the water of lower layer, obtain water process mixing tea oil；
J, it filters：Water process is mixed into the tea oil ultra-filtration membrane device mistake that via hole diameter is 10-15nm in the case where pressure is 1.5-2.5MPa
Filter collects filtering fluid to get prevention of cardiovascular disease tea oil.
2. the preparation method of prevention of cardiovascular disease tea oil according to claim 1, it is characterised in that be by following parts by weight
Raw material is prepared：
50 rosemary powder of tea oil, 3 garlic powder 10
8 cassia seed powder of fish oil, 7 lecithin 4
The white skin powder of 5 lycopene of chrysanthemum powder, 0.01 shaddock 2.
3. the preparation method of prevention of cardiovascular disease tea oil according to claim 1, it is characterised in that be by following parts by weight
Raw material is prepared：
65 rosemary powder of tea oil, 8 garlic powder 6
3 cassia seed powder of fish oil, 3 lecithin 10
The white skin powder of 2 lycopene of chrysanthemum powder, 1 shaddock 4.
4. the preparation method of prevention of cardiovascular disease tea oil according to claim 1, it is characterised in that be by following parts by weight
Raw material is prepared：
58 rosemary powder of tea oil, 6 garlic powder 8
6 cassia seed powder of fish oil, 5 lecithin 7
The white skin powder of 4 lycopene of chrysanthemum powder, 0.5 shaddock 3.
5. the preparation method of prevention of cardiovascular disease tea oil according to claim 1, which is characterized in that the rosemary powder be by
Following methods are prepared：Rosemary leave raw material is cleaned, dried in the shade or be dried to that moisture is less than 8%, then puts into 1-3 times of weight
Petroleum ether in, immersion treatment 1.5-3.0h at normal temperatures, filtering, then by rosemary leave identical weight, 40-60 DEG C of warm water
Washing 2-3 times, is filtered dry moisture, is transferred in baking oven, and moisture is dried at 50-65 DEG C and is less than 5%, reprocesses more than at 40 mesh
Rosemary leave powder；2-4 times of weight is added into rosemary leave powder again, the edible ethanol that volumetric concentration is 90% or more,
Rosemary ethyl alcohol soak is collected in immersion treatment 3-5h at normal temperatures, filtering；It is dense that rosemary ethyl alcohol soak is transferred to falling liquid film
In contracting device, it is dense less than the immersion of 20% rosemary ethyl alcohol that concentration of alcohol is concentrated at being 40-60 DEG C in pressure 5-10KPa, temperature
Contracting liquid；Rosemary ethyl alcohol immersion concentrate is transferred in freezer again, 4-10 DEG C it is quiet put 2-4h, the heavy of precipitation is collected in filtering
It forms sediment, then precipitation is put into baking oven, dried to moisture at 50-65 DEG C and be less than 5%, obtain rosemary dry powder；Again by rosemary
Dry powder extracts through overcritical device in the case where pressure is 0.5-1.75MPa, temperature is 40-55 DEG C, collects light yellow extract, i.e.,
Obtain rosemary powder.
6. according to claim 1 prevent cerebrovascular sclerosis tea oil preparation method, which is characterized in that the garlic powder be by
Following methods are prepared：Garlic Seeds are cleaned, be dried at 40-60 DEG C moisture be less than 12%, be then processed into 40 mesh with
On garlic, then garlic is mixed together with the dry shredded ginger for accounting for garlic weight 3-5%, back and forth through small fire
Stir-fry 5-10min, pulls out, waits for that nature is cooled to room temperature and removes dry shredded ginger, obtains processing garlic；Garlic will be handled again
Put into 1-3 times of weight, volumetric concentration 40-50% edible ethanol in, the immersion treatment 1.0-2.5h at 50-65 DEG C, filtering, obtain
Garlic ethyl alcohol soak；Garlic ethyl alcohol soak is transferred in falling film condenser, is 40-60 DEG C in pressure 5-10KPa, temperature
Under be concentrated into no alcohol, obtain garlic ethyl alcohol impregnate concentrate；It is spray-dried to get garlic that garlic ethyl alcohol is impregnated into concentrate again
Powder.
7. the preparation method of prevention of cardiovascular disease tea oil according to claim 1, which is characterized in that the cassia seed powder be by
Following methods are prepared：Cassia seed is cleaned, dries or is dried to moisture and be less than 8%, be then processed into the Cassia of 20-40 mesh
Sub- coarse powder；Again by cassia seed coarse powder put into 1-2 times of weight, mass fraction be 1.5-3.5% weak caustic solution in, at 40-50 DEG C
Lower immersion 20-45min, filtering obtain processing cassia seed powder then with water washing is purified 1-2 times；Again cassia seed powder will be handled and accounted for
Former cassia seed weight 10-20%, the mixing of processed silica decoloration sand, moisture is dried at 40-60 DEG C and is less than 5%, is obtained
Dry cassia seed mixture；Dry cassia seed mixture is processed into the cassia seed fines of 120 mesh or more through homogenizer, then with 2-3 times
Weight, the edible ethanol solution that volumetric concentration is 50-70% immersion treatment 1.0-2.5h at 50-65 DEG C, filtering obtain cassia seed
Ethyl alcohol soak；Cassia seed ethyl alcohol soak is transferred to shady place, when concentration of alcohol deteriorates to less than 30%, filters, receives
Collect remaining cassia seed ethanol solution；Cassia seed ethanol solution is transferred in falling film condenser again, in pressure 5-10KPa, temperature
Degree is to be concentrated into no alcohol at 40-60 DEG C, obtains cassia seed ethyl alcohol concentrate；Then 5- is put by cassia seed ethyl alcohol concentrate is naturally quiet
The cassia seed precipitation of precipitation is collected in 10h, filtering；Cassia seed is deposited in 50-65 DEG C of drying to moisture and is less than 5%, is crushed, i.e.,
Obtain cassia seed powder.
8. the preparation method of prevention of cardiovascular disease tea oil according to claim 1, which is characterized in that the chrysanthemum powder be by with
Lower section method is prepared：Chrysanthemum medicine materical crude slice is put into the purified water of 2-4 times of weight, 10-25min is boiled in boiling, is filtered, is obtained water cooking liquid；
It is again that water cooking liquid is spray-dried to get chrysanthemum powder.
9. the preparation method of prevention of cardiovascular disease tea oil according to claim 1, which is characterized in that the white skin powder of shaddock is
It is prepared as follows：The white skin of shaddock is put into together with the pure vinegar for accounting for the white tare weight amount 50-70% of shaddock in frying pan, is used
Small fire fries 10-18min back and forth, pulls out, drains, place into boiling water, stir 5-8min back and forth, pulls out, must handle the white skin of shaddock；
The white skin of shaddock will be handled again to be transferred in baking oven, and moisture is dried at 40-60 DEG C and is less than 10%, is then processed into 40 mesh or more
The white skin of shaddock just powder；Again by the beginning of the white skin of shaddock powder put into 2-3 times of weight, volumetric concentration be 70% or more edible ethanol in,
It is impregnated 2-4 days under room temperature, filters, obtain ethyl alcohol soak；Ethyl alcohol soak is transferred in falling film condenser again, in pressure 5-
It is 40-45% that concentration of alcohol is concentrated at 10KPa, 40-60 DEG C of temperature, obtains ethyl alcohol concentrate；Again by ethyl alcohol concentrate through mixing
Column crosses column, and flow velocity 3.2-3.8L/h collects upper prop liquid；Upper prop liquid is transferred in falling film condenser again, pressure 5-10KPa,
It is 2.2-3.4mg/ml that solid content is concentrated at 60-70 DEG C of temperature, obtains concentrate；Concentrate is put into freezer again,
Precipitation is collected in 0-4 DEG C of placement 5-10h, filtering；It will be deposited in 50-65 DEG C of drying to moisture again and be less than 5%, crush to get shaddock
White skin powder.
10. the preparation method of prevention of cardiovascular disease tea oil according to claim 9, which is characterized in that the mixed column be by
200 mesh silica decoloration sand press 3 with 40-60 mesh quartz sands：1 ratio Hybrid assembling forms.
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| CN112568296A (en) * | 2020-12-10 | 2021-03-30 | 湖南油谷高科技有限公司 | Tea oil for enhancing postoperative rehabilitation effect of cancer patient and preparation method thereof |
| CN112568295A (en) * | 2020-12-10 | 2021-03-30 | 湖南油谷高科技有限公司 | Tea oil for preventing enteritis and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112568296A (en) * | 2020-12-10 | 2021-03-30 | 湖南油谷高科技有限公司 | Tea oil for enhancing postoperative rehabilitation effect of cancer patient and preparation method thereof |
| CN112568295A (en) * | 2020-12-10 | 2021-03-30 | 湖南油谷高科技有限公司 | Tea oil for preventing enteritis and preparation method thereof |
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Application publication date: 20181012 |