CN108619060A - Dendrobium moisturizing and skin-tendering composition and application thereof - Google Patents

Dendrobium moisturizing and skin-tendering composition and application thereof Download PDF

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CN108619060A
CN108619060A CN201810744409.2A CN201810744409A CN108619060A CN 108619060 A CN108619060 A CN 108619060A CN 201810744409 A CN201810744409 A CN 201810744409A CN 108619060 A CN108619060 A CN 108619060A
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extract
skin
moisturizing
composition
seed oil
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陈海佳
葛啸虎
王飞
王一飞
陈琳欣
岳坤
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Guangzhou Saliai StemCell Science and Technology Co Ltd
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Guangzhou Saliai StemCell Science and Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/007Preparations for dry skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/78Enzyme modulators, e.g. Enzyme agonists
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/78Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782Enzyme inhibitors; Enzyme antagonists

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  • Oil, Petroleum & Natural Gas (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a dendrobium moisturizing and skin-rejuvenating composition and application thereof, wherein the dendrobium moisturizing and skin-rejuvenating composition comprises a dendrobium extract, pink passion flower seed oil, linden extract and coffee mallow fruit extract; the mass ratio of the dendrobium extract to the pink passion flower seed oil to the linden extract to the coffee yellow sunflower fruit extract is (20-40): 10-20): 15-20): 10-20. The dendrobium extract can activate cells, tighten skin, prevent water loss and supplement water, and simultaneously, the passion flower seed oil with moisture retention, the linden extract and the coffee mallow fruit extract are added to be compounded with the dendrobium extract, so that the synergistic effect of moisture retention is achieved under a certain mass ratio, the product can obviously improve skin quality, improve skin elasticity and supplement the moisture retention effect, and the effect is obviously higher than that of one or two extracts which are added independently.

Description

A kind of tender skin composition of stem of noble dendrobium moisturizing and application thereof
Technical field
The present invention relates to cosmetic technical field, it is specifically related to a kind of tender skin composition of stem of noble dendrobium moisturizing and application thereof.
Background technology
It is one of pathomechanism of aged appearance that skin water content, which continuously decreases, when the water content of cuticula is less than 10% When, there is crack in dry skin, furfur, imbricate keratinocyte layer arranged in parallel, and skin is easy by external environment physics The erosion of factor, water, electrolyte in skin are also easy evaporation or are lost in.Skin moisture-keeping be ensure cuticula barrier function and The most important basic means improved looks.Moisturizer is mainly by preventing the loss of moisture in skin and absorbing external environment Moisture achieve the purpose that skin includes certain moisture, the moisturizing active constituent more approved at present is bionical dose of class, such as god Through amide, hyaluronic acid, pyrrolones carboxylic acid sodium etc., after being absorbed by skin, it can be combined with the free water in skin and be allowed to not allow Volatile to play moisture-keeping function, main problem is such components unstable chemcial property, and the content in product system is normal Because internal and external factor gradually reduces, it is unable to reach effective threshold value, the moistening effect of itself is not notable.
The stem of noble dendrobium is China's rare traditional Chinese medicine, is put into world's endangered protection plant, 76 kinds known to China, the whole world is about There are 1500 kinds.《Sheng Nong's herbal classic》Deng record, the stem of noble dendrobium has eliminating impediment, lower gas, tonifying five zang organs consumptive disease, by skin heat symptoms caused by an exopathgen, Qiang Yin And other effects, it has been investigated that the stem of noble dendrobium can significantly improve superoxide dismutase (SOD) level, lipid peroxide (LPO) is reduced, is adjusted It is horizontal to save brain monoaminergic transmitters, inhibits similar monoamine oxidase (MAO), plays the role of anti-aging.It received in recent years The dendrobium polysaccharide of concern also has the multiple efficacies such as significant immune-enhancing activity and anti-aging, radioresistance, such as Tiepi Fengdou The brilliant, stem of noble dendrobium dissipates, peaceful, the beneficial intestines soup of clearing, noble dendrobium stem distillate, stem of noble dendrobium essence, yin-nourishing oral solution and stem of noble dendrobium piece etc..With dendrobium candidum processing " maple bucket " or " earrings dendrobium " are referred to as " golden ear dendrobium ", " dendrobium ring ", " Jin Fengdou ", are in great demand in Southeast Asia and America and Europe.
In the prior art by compound less of Herba Dendrobii extract and other compositions.
Invention content
It is an object of the invention to overcome the above problem and provide a kind of tender skin composition of moisturizing and application thereof, the moisturizing is tender Skin composition is directed to dry skin problem, using the mutual synergistic effect of the active constituent of various plants extract, is protected with playing The effect of wet tender skin.
To achieve the above object, the technical solution adopted by the present invention is that a kind of tender skin composition of moisturizing, including the stem of noble dendrobium extracts Object, maypop seed oil, bodhi tree extract, Abelmoschus esculentus berry extract;The Herba Dendrobii extract, maypop seed Oil, bodhi tree extract, Abelmoschus esculentus berry extract mass ratio be (20~40):(10~20):(15~20):(10~ 20)。
Single extract is usually used in the prior art and carries out the tender skin of moisturizing, however its effect is ideal not to the utmost, the application Inventor has found by numerous studies, and Herba Dendrobii extract, maypop seed oil, bodhi tree extract, Abelmoschus esculentus fruit are carried Object is taken to be compounded, the tender skin significant effect of moisturizing is better than independent extract.
Preferably, the Herba Dendrobii extract, maypop seed oil, bodhi tree extract, Abelmoschus esculentus berry extract Mass ratio is (25~35):(10~15):(15~17.5):(15~20).
In the present composition, the proportioning of component can influence the effect of composition, the study found that in the preferred quality Than in range, the tender skin of moisturizing of the present composition is better.
Preferably, the Herba Dendrobii extract, maypop seed oil, bodhi tree extract, Abelmoschus esculentus berry extract Mass ratio is 30:10:15:20.
Applicant has been surprisingly found that in many experiments, under the specific mass ratio, the moistening effect of the present composition Reach best.
Preferably, the mass ratio of the Herba Dendrobii extract and maypop seed oil is 3:1.
Applicant has been surprisingly found that Herba Dendrobii extract is with maypop seed oil in the specific mass ratio in many experiments Under, the moistening effect of the present composition reaches very good effect.
Preferably, the mass ratio of the Herba Dendrobii extract and Abelmoschus esculentus berry extract is 3:2.
Applicant has been surprisingly found that Herba Dendrobii extract is with Abelmoschus esculentus berry extract in the specific quality in many experiments Than under, the present composition can be effectively improved cutaneous roughness, and skin is more soft.
Application of the tender skin composition of moisturizing in preparing skin care item.
A kind of skin care item containing the tender skin composition of the moisturizing.
Preferably, the tender skin composition of moisturizing mass percent in the skin care item is 1~6%.
Preferably, the tender skin composition of moisturizing mass percent in the skin care item is 5%.
Preferably, the dosage form of the skin care item is aqua, creme, finish, washing lotion or emulsion.
The tender skin composition main component of moisturizing of the present invention and effect are as follows:
The stem of noble dendrobium:It has been investigated that the stem of noble dendrobium can significantly improve superoxide dismutase (SOD) level, lipid peroxide is reduced (LPO), it is horizontal that brain monoaminergic transmitters are adjusted, inhibits similar monoamine oxidase (MAO), plays the role of anti-aging.Closely A little dendrobium polysaccharide being concerned in year also have the multiple efficacies such as significant immune-enhancing activity and anti-aging, radioresistance, such as Capsule Dendrobii, the stem of noble dendrobium dissipate, clearing is peaceful, beneficial intestines soup, noble dendrobium stem distillate, stem of noble dendrobium essence, yin-nourishing oral solution and stem of noble dendrobium piece etc..With dendrobium candidum " the maple bucket " or " earrings dendrobium " of processing is referred to as " golden ear dendrobium ", " dendrobium ring ", " Jin Fengdou ", is in great demand in Southeast Asia And it is American-European.
Maypop seed oil:Containing essential fatty acid -- linoleic acid is up to 70% or more, belongs to base oil.Promote The essential nutritional ingredient of damaged skin regeneration.Has Dimethicone Copolyol, skin sense is soft and dry and comfortable, by maypop seed Oil is applied in skin care item, can be effectively increased shelf-life and the stability of skin care item, can also form one layer of guarantor in skin surface Cuticula reduces skin water loss.
Bodhi tree:Bodhi tree (Ficus religiosa) is Moraceae banyan seeds, and Chinese nickname has more sieve of Ali, India Bodhi tree, thinking tree, complete alms bowl Luo Shu, feel tree etc., cosmetics use the bark of its drying.Contain β-paddy steroid in bodhi tree orange peel Alcohol-D-Glucose glycosides, this ingredient play the role of blood glucose, the also alkaloid containing resin and trace.Miquel linden bark extract is used for Anti-aging cosmetics effectively facilitate collagen synthesis, help reconstructed fiber tissue and increase the corium degree of packing, enable skin more It compacts, face contour is apparent;Abundant nutrition and oxygen part are provided for cell, accelerates flesh bottom microcirculation and cell more raw, helps and carry Rise skin gloss;100% inhibits Collagenases, prevents from destroying collagen fabric;Powerful anti-free radical effect prevents oxidation from drawing Premature cell senescence is caused, keeps skin more moist.
Abelmoschus esculentus fruit:Abelmoschus esculentus is annual herb plant also known as okra, swordweed, kidney tonifying grass, loosestrife Deng.China the South and the North various regions have the distribution and cultivation of okra, American to be referred to as " plant vigour ", and Japanese is referred to as " Green Ginseng ", it is also set to the preferred vegetables of sportsman by many countries, be it is a kind of have better nutritivity and medical value New type of health vegetables.In okra rich in protein, fat, carbohydrate, vitamin, minerals and dietary fiber, flavones, Pectin, polysaccharide and other functional ingredient, especially okra green bean fruit in the mucoid material that is rich in, be by poly galactolipin, half The mixture of newborn glycan and araban and pectin, wherein pectin are a kind of Soluble Fibers, it can promote internal organic matter The excretion of matter reduces the accumulation of toxin, reduces the content of blood glucose and cholesterol.Glutinous sliding juice can help digest, and prevent constipation.Tool Have cancer anticancer, tonifying kidney and strengthening yang, strengthen immunity, it is aid digestion the effects that.Water-soluble fibre pectin, polysaccharide in okra is to skin Also there is good health-care effect, smashing okra okra fruit to pieces taking juice has unique beautifying face and moistering lotion for skin care, increases skin Skin elasticity and anti-aging dispel pigmentation, make skin-whitening, delicate effect.
Beneficial effects of the present invention:There is Herba Dendrobii extract activating cell, firm skin to prevent water loss, supplement water The moistening effect divided, the present invention adds maypop seed oil, bodhi tree extract, Abelmoschus esculentus berry extract simultaneously, with stone Dry measure used in former times extract compounds, and the synergy synergistic effect of the tender skin of moisturizing is played, in various plants extract a certain range mass ratio Under, it acts synergistically, product is allow to be obviously improved skin quality, improve skin elasticity, the moistening effect to keep the skin wet, effect is bright It is aobvious to add one of which or two kinds of extracts higher than independent.
Specific implementation mode
To better illustrate the object, technical solutions and advantages of the present invention, below in conjunction with specific embodiment to the present invention It is described further.
Each raw material involved by following embodiment is the commercially available universal product unless otherwise instructed.Herba Dendrobii extract, bodhi tree Extract, Abelmoschus esculentus berry extract are fat-soluble extract.
A kind of tender skin composition of moisturizing, including Herba Dendrobii extract, maypop seed oil, bodhi tree extract, coffee Huang Certain herbaceous plants with big flowers berry extract;Wherein, the quality of Herba Dendrobii extract, maypop seed oil, bodhi tree extract, Abelmoschus esculentus berry extract Than for (20~40):(10~20):(15~20):(10~20).
The composition of the present invention can be by by Herba Dendrobii extract, maypop seed oil, bodhi tree extract, Abelmoschus esculentus Berry extract is mixed to get by the mass ratio.
The present invention also provides by the tender skin composition of above-mentioned moisturizing, applied in skin care item, skin care item include following quality hundred Divide the ingredient of ratio:The tender skin composition 1~6% of above-mentioned moisturizing, cetostearyl alcohol 0.5~1%, stearine and PEG-100 Stearine 0.5~3%, evening primrose oil 0.5~2%, tea-seed oil 1~2%, dimethyl silicone polymer 2~3%, oxybenzene Methyl esters 0.1~0.3%, isopropyl palmitate 2~3%, glycerine 5~10%, propylene glycol 2~8%, glycine betaine 5~10%, propylene Sour (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer 0.2~0.5%, surplus are deionized water.
The preparation method of the skin care item, includes the following steps:
1) by propylene glycol, glycine betaine, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer, glycerine, oxybenzene Methyl esters deionized water is added in A pots, is heated to 85~90 DEG C, stirring and dissolving;
2) by the tender skin composition of moisturizing, cetostearyl alcohol, stearine and see PEG-100 stearines, the moon Careless oil, tea-seed oil, dimethyl silicone polymer, isopropyl palmitate component are added in B pots, are heated with stirring to 80-85 DEG C, have disperseed Emulsification pot is pumped into after complete;
3) material in A pots being slowly pumped into emulsification pot through filter screen and is emulsified, homogeneous stops homogeneous after five minutes, Open cycle water cools down, and is kept stirring and vacuumizes defoaming;When continuing to be cooled to 36 DEG C, discharge to get finished product.
Embodiment 1
A kind of tender skin composition of moisturizing, including Herba Dendrobii extract, maypop seed oil, bodhi tree extract, coffee Huang Certain herbaceous plants with big flowers berry extract;Wherein, the quality of Herba Dendrobii extract, maypop seed oil, bodhi tree extract, Abelmoschus esculentus berry extract Than being 30:10:15:20.
The preparation method of the composition is as described above.
The present embodiment, which additionally provides, is applied to above-mentioned moisturizing tender skin composition in skin care item, and skin care item include following quality The ingredient of percentage:The tender skin composition 5% of above-mentioned moisturizing, cetostearyl alcohol 0.5%, stearine and PEG-100 glycerine Stearate 2%, evening primrose oil 1.5%, tea-seed oil 1.2%, dimethyl silicone polymer 2.5%, methyl hydroxybenzoate 0.2%, palm Isopropyl propionate 2%, glycerine 5%, propylene glycol 5%, glycine betaine 6%, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters crosslinking are poly- Close object 0.2%, surplus is deionized water.
The preparation method of the skin care item, as described above.
Embodiment 2
A kind of tender skin composition of moisturizing, including Herba Dendrobii extract, maypop seed oil, bodhi tree extract, coffee Huang Certain herbaceous plants with big flowers berry extract;Wherein, the quality of Herba Dendrobii extract, maypop seed oil, bodhi tree extract, Abelmoschus esculentus berry extract Than being 25:15:15.5:15.
The present embodiment, which additionally provides, is applied to above-mentioned moisturizing tender skin composition in skin care item, and skin care item include following quality The ingredient of percentage:The tender skin composition 6% of above-mentioned moisturizing, cetostearyl alcohol 0.8%, stearine and PEG-100 glycerine Stearate 2.5%, evening primrose oil 0.5%, tea-seed oil 1%, dimethyl silicone polymer 2%, methyl hydroxybenzoate 0.3%, palmitic acid Isopropyl ester 2.5%, glycerine 6%, propylene glycol 2%, glycine betaine 5%, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters crosslinking are poly- Object 0.3% is closed, surplus is deionized water.
The composition of the present embodiment and the preparation method of skin care item are same as Example 1.
Embodiment 3
A kind of tender skin composition of moisturizing, including Herba Dendrobii extract, maypop seed oil, bodhi tree extract, coffee Huang Certain herbaceous plants with big flowers berry extract;Wherein, the quality of Herba Dendrobii extract, maypop seed oil, bodhi tree extract, Abelmoschus esculentus berry extract Than being 20:10:20:10.
The present embodiment, which additionally provides, is applied to above-mentioned moisturizing tender skin composition in skin care item, and skin care item include following quality The ingredient of percentage:The tender skin composition 4% of above-mentioned moisturizing, cetostearyl alcohol 0.6%, stearine and PEG-100 glycerine Stearate 3%, evening primrose oil 2%, tea-seed oil 1.5%, dimethyl silicone polymer 3%, methyl hydroxybenzoate 0.3%, palmitic acid are different Propyl ester 3%, glycerine 6%, propylene glycol 2%, glycine betaine 6%, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymers 0.4%, surplus is deionized water.
The composition of the present embodiment and the preparation method of skin care item are same as Example 1.
Embodiment 4
A kind of tender skin composition of moisturizing, including Herba Dendrobii extract, maypop seed oil, bodhi tree extract, coffee Huang Certain herbaceous plants with big flowers berry extract;Wherein, the quality of Herba Dendrobii extract, maypop seed oil, bodhi tree extract, Abelmoschus esculentus berry extract Than being 35:12:17.5:19.
The present embodiment, which additionally provides, is applied to above-mentioned moisturizing tender skin composition in skin care item, and skin care item include following quality The ingredient of percentage:The tender skin composition 4% of above-mentioned moisturizing, cetostearyl alcohol 1%, stearine and PEG-100 glycerine are hard Resin acid ester 1.5%, evening primrose oil 1.5%, tea-seed oil 2%, dimethyl silicone polymer 2%, methyl hydroxybenzoate 0.1%, palmitic acid are different Propyl ester 2.5%, glycerine 10%, propylene glycol 8%, glycine betaine 10%, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters crosslinking are poly- Object 0.5% is closed, surplus is deionized water.
The composition of the present embodiment and the preparation method of skin care item are same as Example 1.
Embodiment 5
A kind of tender skin composition of moisturizing, including Herba Dendrobii extract, maypop seed oil, bodhi tree extract, coffee Huang Certain herbaceous plants with big flowers berry extract, wherein Herba Dendrobii extract, maypop seed oil, bodhi tree extract, Abelmoschus esculentus berry extract quality Than being 40:10:15:10.
The present embodiment, which additionally provides, is applied to above-mentioned moisturizing tender skin composition in skin care item, and skin care item include following quality The ingredient of percentage:The tender skin composition 1% of above-mentioned moisturizing, cetostearyl alcohol 0.8%, stearine and PEG-100 glycerine Stearate 0.5%, evening primrose oil 2%, tea-seed oil 1.8%, dimethyl silicone polymer 2.5%, methyl hydroxybenzoate 0.1%, palm Isopropyl propionate 2.5%, glycerine 5%, propylene glycol 2%, glycine betaine 10%, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters are handed over Linked polymer 0.4%, surplus are deionized water.
The composition of the present embodiment and the preparation method of skin care item are same as Example 1.
Embodiment 6
A kind of tender skin composition of moisturizing, including Herba Dendrobii extract, maypop seed oil, bodhi tree extract, coffee Huang Certain herbaceous plants with big flowers berry extract, wherein Herba Dendrobii extract, maypop seed oil, bodhi tree extract, Abelmoschus esculentus berry extract quality Than being 20:20:20:20.
The present embodiment, which additionally provides, is applied to above-mentioned moisturizing tender skin composition in skin care item, and skin care item include following quality The ingredient of percentage:The tender skin composition 2% of above-mentioned moisturizing, cetostearyl alcohol 0.6%, stearine and PEG-100 glycerine Stearate 0.4%, evening primrose oil 1.5%, tea-seed oil 1.8%, dimethyl silicone polymer 2.5%, methyl hydroxybenzoate 0.1%, palm fibre Palmitic acid isopropyl propionate 2.5%, glycerine 6%, propylene glycol 4%, glycine betaine 10%, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters Cross-linked polymer 0.4%, surplus are deionized water.
The composition of the present embodiment and the preparation method of skin care item are same as Example 1.
Comparative example 1
1 difference from Example 1 of comparative example is that the tender skin composite formula of the moisturizing is 5% Herba Dendrobii extract.
Comparative example 2
2 difference from Example 1 of comparative example is that the tender skin composite formula of the moisturizing is 5% maypop Seed oil.
Comparative example 3
3 difference from Example 1 of comparative example is that the tender skin composite formula of the moisturizing extracts for 5% bodhi tree Object.
Comparative example 4
4 difference from Example 1 of comparative example is that the tender skin composite formula of the moisturizing is 5% Abelmoschus esculentus fruit Extract.
Comparative example 5
The formula of the tender skin composition of 5 moisturizing of comparative example is:Herba Dendrobii extract, maypop seed oil;Wherein, the stem of noble dendrobium extracts Object, maypop seed oil mass ratio be 30:10.
Comparative example 6
The formula of the tender skin composition of moisturizing of comparative example 6 is:Bodhi tree extract, Abelmoschus esculentus berry extract;Wherein, Bodhisattva Carry tree extract, the mass ratio of each substance of Abelmoschus esculentus berry extract is 15:20.
Comparative example 7
The formula of the tender skin composition of moisturizing of comparative example 7 is:Maypop seed oil, bodhi tree extract, Abelmoschus esculentus Berry extract;Wherein, maypop seed oil, bodhi tree extract, Abelmoschus esculentus berry extract mass ratio be 10:15:20.
Comparative example 8
The formula of the tender skin composition of moisturizing of comparative example 8 is:Herba Dendrobii extract, maypop seed oil, bodhi tree extraction Object, Abelmoschus esculentus berry extract;Wherein, Herba Dendrobii extract, maypop seed oil, bodhi tree extract, Abelmoschus esculentus fruit carry It is 10 to take the mass ratio of each substance of object:20:15:20.
Comparative example 9
The formula of the tender skin composition of moisturizing of comparative example 9 is:Herba Dendrobii extract, maypop seed oil, bodhi tree extraction Object, Abelmoschus esculentus berry extract;Wherein, Herba Dendrobii extract, maypop seed oil, bodhi tree extract, Abelmoschus esculentus fruit carry It is 45 to take the mass ratio of object:30:15:27.
Experiment effect
1, guinea pig skin stimulation test
The tender skin composition of 0.5g Examples 1 to 6 moisturizings is respectively taken, being diluted to 100g using deionized water is configured to test sample Product.Given the test agent using skin irritation test method (《Skin care item hygienic practice》2007 editions toxicology test methods) it is surveyed Examination.
Experimental animal:Cavy weight 250g~300g.
Experimental result:Through 14 days Skin Irritation Tests, stimulate the reaction is had no.
2, sample moistening effect
2.1 experimental method
According to the prior art (Wang Libo, Yan Huiju etc., the measurement new method of skin care item performance of keeping humidity, toothpaste industry, 2006 The 3rd phase of year) it measures, it bends side in candidate or so forearm and marks 3 × 3cm2The square Experimental Area of size, using left arm as guarantor The test zone of wet product, the corresponding symmetrical region of right arm are blank control, then use Corneometer CM825 test detections every The moisture of a experiment position, is repeated 5 times respectively, obtains average value.Embodiment 1 to 6 and comparative example 1 are calculated with formula (1) To the hydration rate of the tender skin composition of 9 moisturizings;The results are shown in Table 1;
Hydration rate=100% × (test group-blank value)/blank value.
3.2 experimental result
Table 1
As can be seen from Table 1, the result that above-mentioned each composition moisturizing rate changes over time, the results showed that different moisturizer are protected The sequence of wet rate is:1 composition of the embodiment of the present invention>4 composition of the embodiment of the present invention>2 composition of the embodiment of the present invention>This hair 3 composition of bright embodiment>5 composition of the embodiment of the present invention>6 composition of the embodiment of the present invention>>The composition of comparative example 9>Comparison The composition of example 8>5~7 composition of comparative example>>1~4 composition of comparative example.From the results shown in Table 1, the stem of noble dendrobium is extracted Object, maypop seed oil, bodhi tree extract, the equal Saccharideisomerate of Abelmoschus esculentus berry extract, and four kinds are extracted Object is compounded, synergistic, and moistening effect is significantly better than independent extract or two of which extract.
Herba Dendrobii extract, maypop seed oil, bodhi tree extract, Abelmoschus esculentus berry extract group in comparative example 8,9 The mass ratio for closing object is not complete within the scope of the present invention, it can be seen that its effect is not as good as the present invention, it is seen that Herba Dendrobii extract, pink colour Four kinds of passionflower seed oil, bodhi tree extract, Abelmoschus esculentus berry extract extracts are combined by mass ratio of the present invention one It rises, keeps the moistening effect of skin care item of the present invention more preferable, also, as shown in Table 1, as Herba Dendrobii extract, maypop seed oil, Bodhisattva Tree extract, Abelmoschus esculentus berry extract are carried, the mass ratio of each substance is 30:10:15:When 20, the moisturizing of skin care item of the present invention Effect is best.
3, the tender skin effect assessment of the present invention
This effect example has investigated Herba Dendrobii extract with the mass ratio of Abelmoschus esculentus berry extract to the tender skin of the present composition The influence of effect.In order to investigate the influence, we are prepared for different compositions according to the method for embodiment 1.Each experimental group group It includes following component to close object, Herba Dendrobii extract, maypop seed oil, bodhi tree extract, Abelmoschus esculentus berry extract, In, Herba Dendrobii extract, maypop seed oil, bodhi tree extract, Abelmoschus esculentus berry extract mass ratio be (20~40): (10~20):(15~20):(10~20).
The mass ratio of wherein Herba Dendrobii extract and Abelmoschus esculentus berry extract is as shown in table 2 below.
Table 2
Experimental method:
Subject amounts to 40 people.Specific sex composition determines at random.If period there are 2 people adverse reaction occur, survey is terminated Examination;As a result adverse reaction is not found.After subject has smeared composition made from experimental group 1~4 of the present invention, the roughness of skin Have clear improvement, the smooth exquisiteness of change.
1. selecting the left and right eye of subject as tested region.Every subject's left eye smears given the test agent, and (present invention is real Test composition made from group 1~4) it is used as sample sets, right eye to smear any sample as a control group.
2. before smearing skin care item using skin lens image analysis system and moisture content of skin tester determination experiment position Dermatoglyph degree.
3. detection product is smeared in the tested area (the same area) cleaned by clear water sooner or later daily, during experiment, by Examination person cannot apply the other any skin care item erased outside tested sample in Test sites.
4. subject is after being used continuously given the test agent one week, two weeks, three weeks and four weeks, same time subject will weekly It smears position to clean, is measured using skin lens image analysis system and moisture content of skin tester by tester and smear number positional Value.
5. the numerical value that statistics subject position measures every time, the variation rule of analyzing skin texture and moisture Rule.
As a result:
(1) dermatoglyph situation of change:
Change rate=(number of sets of sample is according to Tn-initial value T0)/initial value T0× 100%
Relative change rate=(number of sets of sample is according to Tn-blank control group data Tn)/blank control group data Tn × 100%
T0It is the preceding subjects skin's measured value of experiment, Tn is skin measured value when each subject tests at each time point every time.
1, skin roughness (Skin Roughness SR)
Skin roughness is in all sections of skin, with the difference on straight line between maximum gray scale peak value and minimal gray peak value Value.The parameter is the maximum height of skin surface unevenness.
The difference of table 3 recipient site skin roughness and initial value
Within 4 weeks test periods, after recipient site uses present composition sample, skin roughness is in reduce always Trend, and be negative value, relative change rate is negative value always, and is in reduction trend;It can be seen that from the data of table 3 by the stem of noble dendrobium Extract and Abelmoschus esculentus berry extract are compounded according to said ratio, can be effectively improved cutaneous roughness, and wherein With the mass ratio 3 of Herba Dendrobii extract and Abelmoschus esculentus berry extract:2 is best.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention With within principle, any modification, equivalent substitution, improvement and etc. done should be included within the scope of protection of the invention god.

Claims (10)

1. a kind of tender skin composition of moisturizing, which is characterized in that include Herba Dendrobii extract, maypop seed oil, bodhi tree extraction Object, Abelmoschus esculentus berry extract;The Herba Dendrobii extract, maypop seed oil, bodhi tree extract, the extraction of Abelmoschus esculentus fruit The mass ratio of object is (20~40):(10~20):(15~20):(10~20).
2. the tender skin composition of moisturizing according to claim 1, which is characterized in that the Herba Dendrobii extract, maypop Seed oil, bodhi tree extract, Abelmoschus esculentus berry extract mass ratio be (25~35):(10~15):(15~17.5):(15 ~20).
3. according to the tender skin composition of moisturizing described in claim 1, which is characterized in that the Herba Dendrobii extract, maypop seed Oil, bodhi tree extract, Abelmoschus esculentus berry extract mass ratio be 30:10:15:20.
4. according to the tender skin composition of moisturizing described in claim 1, which is characterized in that the Herba Dendrobii extract and maypop seed The mass ratio of oil is 3:1.
5. according to the tender skin composition of moisturizing described in claim 1, which is characterized in that the Herba Dendrobii extract is carried with Abelmoschus esculentus fruit It is 3 to take the mass ratio of object:2.
6. according to application of the tender skin composition of any one of Claims 1 to 5 moisturizing in preparing skin care item.
7. a kind of skin care item containing the tender skin composition of the moisturizing as described in any one of Claims 1 to 5.
8. skin care item according to claim 7, which is characterized in that the tender skin composition of moisturizing is in the skin care item Mass percent is 1~6%.
9. skin care item according to claim 7, which is characterized in that the tender skin composition of moisturizing is in the skin care item Mass percent is 5%.
10. skin care item according to claim 7, which is characterized in that the dosage form of the skin care item be aqua, creme, finish, Washing lotion or emulsion.
CN201810744409.2A 2018-07-09 2018-07-09 Dendrobium moisturizing and skin-tendering composition and application thereof Withdrawn CN108619060A (en)

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CN105534831A (en) * 2016-03-17 2016-05-04 易智彪 Dendrobium officinale leaf extract with moisturizing effect and application thereof to preparation of skin care product
CN106491428A (en) * 2016-11-14 2017-03-15 广州蜜妆生物科技有限公司 A kind of NMF
CN107982201A (en) * 2017-12-05 2018-05-04 广州赛莱拉干细胞科技股份有限公司 A kind of moisture-keeping composition containing radix astragali stem cell extract and its application

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CN105395441A (en) * 2015-12-30 2016-03-16 广州蜜妆生物科技有限公司 Overall-efficiency oil-controlling acne-removing pockmark-eliminating skin-beautifying essence
CN105534831A (en) * 2016-03-17 2016-05-04 易智彪 Dendrobium officinale leaf extract with moisturizing effect and application thereof to preparation of skin care product
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Application publication date: 20181009