CN1085792A

CN1085792A - Treat bathomorphic liniment and preparation method thereof

Info

Publication number: CN1085792A
Application number: CN93108883A
Authority: CN
Inventors: 高峰
Original assignee: Individual
Current assignee: Individual
Priority date: 1993-07-30
Filing date: 1993-07-30
Publication date: 1994-04-27

Abstract

The invention discloses the bathomorphic medicine for external use of a kind of treatment, it is formulated that it handles the back by 5 groups of Chinese herbal medicine through different processing method, can be used for treating myopia, and astigmatic, presbyopia, and can treat the intraocular pressure that optic neuritis, glaucoma cause and cross high oculopathy.

Description

Treat bathomorphic liniment and preparation method thereof

The present invention is bathomorphic externally-applied medicinal composition of treatment and preparation method thereof, be specifically related to treat myopia (comprising pseudomyopia and true myopia) and astigmatism, presbyopia, and can treat the intraocular pressure that optic neuritis, glaucoma cause and cross liniment of high ocular disease and preparation method thereof.

At present, utilize liniment to treat that bathomorphic medicine is known a bathomorphic collyrium of a kind of treatment, directly drop in affected part, easily causing stimulates and incompatible sense, and its curative effect is general and be difficult to long-term after treatment effect or fundamentally cure.The bathomorphic medicine eyeshield of a kind of treatment is arranged in addition, medicine is housed in the medicated bag, but prescription is not open, only pseudomyopia is had certain curative effect.

The objective of the invention is according to traditional Chinese medical science inner disease outer treat theory, provide from the direct administration in position, oculopathy district, a kind of natural drug composition of non-stimulated, no sense of discomfort treatment myopia outstanding effect, this medicine is made powder, not only can treat myopia, can also treat oculopathy such as astigmatism, presbyopia and glaucoma.

Another object of the present invention provides the manufacture method of this pharmaceutical composition.

The present invention from life make eye bright, the clear blind air slaking stasis of blood of promoting the production of body fluid, loose, common five groups of natural materials are made pharmaceutical composition.

Medicine of the present invention is made up of following five groups of components: (by weight)

First group: 50 parts of Radix Rhodiolaes, 10 parts of Fel Ursis, 10 parts of Calculus Boviss, 10 parts of Calaminas, 40 parts of Rhizoma Coptidis, 50 parts of Magnetitums, 100 parts of Borneolum Syntheticums, 50 parts of Concha Haliotidis;

Second group: 50 parts of Rhizoma Atractylodis, 40 parts of the Cortexs Eucommiae, 50 parts of Fructus Rosae Laevigatae, 30 parts of Semen Ziziphi Spinosaes, 50 parts of Radix Polygalaes, 50 parts of Rhizoma Acori Graminei, 20 parts of the Radix Paeoniae Albas, 30 parts of Radix Paeoniae Rubra;

The 3rd group: 30 parts of Periostracum Cicadaes, 50 parts of Herba Schizonepetaes, 50 parts of the Rhizoma Anemarrhenaes, 50 parts of Cortex Phellodendris;

The 4th group: 20 parts in the Radix Rehmanniae, 100 parts of Herba Dendrobiis, 50 parts of Herba Ecliptaes, 50 parts in Radix Rehmanniae Preparata, 50 parts of Radix Angelicae Sinensis, 50 parts of Radix Scrophulariaes, 30 parts of Fructus Leonuris;

The 5th group: 30 parts in Rhizoma Gastrodiae, 30 parts of the Radixs Angelicae Dahuricae, 10 parts of Herba Asaris, 50 parts of Herba Menthaes, 30 parts on Flos Carthami, 30 parts of Radix Salviae Miltiorrhizaes, 50 parts of Flos Chrysanthemis, 50 parts of Herba Schizonepetae, 40 parts of Poria cum Radix Pinis, 30 parts of Fructus Mori, 30 parts of Semen Cassiaes, 20 parts of Fructus Viticises, 30 parts of Radix Gentianae, 10 parts of Flos Eriocaulis, 20 parts of Semen Celosiae, 150 parts of Fructus Lycii, 15 parts of Fructus Schisandrae Chinensis, 50 parts of Radix Stellariaes, 30 parts of angelicas, 50 parts of Lignum Aquilariae Resinatum, 30 parts of Herba Equiseties Hiemalis, 100 parts of Herba Senecionis Scandentiss, 100 parts of Radix Codonopsis, 30 parts of Radix Saposhnikoviaes, 30 parts of Faeces Vespertilioniss.

With above-mentioned natural materials, by described consumption and manufacture method given below, make five groups of pharmaceutical compositions respectively, carry out promptly getting behind the combination drying levigation and treat bathomorphic liniment.

Provide the manufacture method of this medicine below in detail:

Earlier Magnetitum, Rhizoma Coptidis, Calamina, Radix Rhodiolae, Concha Haliotidis levigation in first group are packed in the cloth bag, carry out the decocting in water extraction with Fel Ursi, Borneolum Syntheticum, Calculus Bovis with distilled water again, remove slag and filter the group pharmaceutical extraction liquid of promptly winning;

Second group of medicine fried to the little Huang of epidermis with low baking temperature, and levigation gets second group of drug powder;

The 3rd group of drug salt water logging after drying, levigation are got the 3rd group of drug powder;

The 4th group of medicine with yellow wine immersion, steaming and decocting, taken out dry back levigation and get the 4th group of drug powder;

Behind the 5th group of medicine usefulness Warm Wash decontamination, water logging 36～48 hours, dry levigation gets the 5th group of drug powder;

Above one to five group of mix homogeneously is promptly got the bathomorphic pharmaceutical composition of external application for curing.

Advantage of the present invention is owing to adopted Radix Rhodiolae to have anti-fatigue effect, adopted causing resuscitation with aromatic drugs, blood circulation promoting and blood stasis dispelling, anti-inflammatory analgetic simultaneously, medicine such as blind clearly makes eye bright, can eliminate eyes muscular fatigue after the external application, but spasmolytic emergency, can increase eye muscle nutrition by the acupuncture point infiltration, do not stimulate and sense of discomfort, can fundamentally cure myopia.

Manufacture method of the present invention is simple and easily capable, can give full play to drug effect.

Be elaborated below in conjunction with embodiment, should propose, the present invention is a kind of pharmaceutical composition and preparation method thereof, no matter be above-mentioned scheme or the following examples, for those skilled in the art, be easy to make certain improvement or variation, therefore say, can not think that scheme and embodiment are exactly the concrete qualification of inventor to its invention, but for the present invention is described.

Embodiment 1:

First group: Radix Rhodiolae 50g, Fel Ursi 10g, Calculus Bovis 10g, Calamina 10g, Rhizoma Coptidis 40g, Magnetitum 50g, Borneolum Syntheticum 100g, Concha Haliotidis 50g, earlier with Magnetitum, Radix Rhodiolae, Rhizoma Coptidis, Calamina, Concha Haliotidis levigation, crossing 100 mesh sieves wraps with cloth bag, above-mentioned each material is put into 5000g distilled water decocting in water extraction 2 hours jointly, remove slag and filter the group pharmaceutical extraction liquid of winning, standby;

Second group: Rhizoma Atractylodis 50g, Cortex Eucommiae 40g, Fructus Rosae Laevigatae 50g, Semen Ziziphi Spinosae 30g, Radix Polygalae 50g, Rhizoma Acori Graminei 50g, Radix Paeoniae Alba 20g, Radix Paeoniae Rubra 30g; Carry out three low baking temperature parches after the mixing, each 15 minutes, parch for the first time dropped into Mel 100g; Parch for the second time drops into flour 100g; Parch for the third time drops into rice vinegar 20g, fries to the no smell of vinegar of the little Huang of epidermis, and levigation is crossed 100 mesh sieves and got second group of drug powder, and is standby;

The 3rd group: Periostracum Cicadae 30g, Herba Schizonepetae 50g, Rhizoma Anemarrhenae 50g, Cortex Phellodendri 50g; Saline solution with concentration 10% soaked 48 hours, and dry levigation is crossed 100 mesh sieves and got the 3rd group of drug powder, and is standby;

The 4th group: Radix Rehmanniae 20g, Herba Dendrobii 10g, Herba Ecliptae 50g, Radix Rehmanniae Preparata 50g, Radix Angelicae Sinensis 50g, Radix Scrophulariae 50g, Fructus Leonuri 30g, to soak 100 hours with yellow wine, the back is taken out and was steamed 2 hours, and the oven dry levigation is crossed 100 mesh sieves and got the 4th group of drug powder, and is standby;

The 5th group: Rhizoma Gastrodiae 30g, Radix Angelicae Dahuricae 30g, Herba Asari 10g, Herba Menthae 50g, Flos Carthami 30g, Radix Salviae Miltiorrhizae 30g, Flos Chrysanthemi 50g, Herba Schizonepetae 50g, Poria cum Radix Pini 40g, Fructus Mori 30g, Semen Cassiae 30g, Fructus Viticis 20g, Radix Gentianae 30g, Flos Eriocauli 10g, Semen Celosiae 20g, Fructus Lycii 150g, Fructus Schisandrae Chinensis 15g, Radix Stellariae 50g, angelica 30g, Lignum Aquilariae Resinatum 50g, Herba Equiseti Hiemalis 20g, Herba Senecionis Scandentis 100g, Radix Codonopsis 100g, Radix Saposhnikoviae 30g, night bright noisy 30g, with above-mentioned flush away impurity with 50 ℃ of water loggings bubbles after 48 hours the oven dry levigation cross 100 mesh sieves, get the 5th group of drug powder, standby.

First group of pharmaceutical extraction liquid and second and third, four, five groups of drug powders are stirred, be about to treat bathomorphic liniment compositions after the drying, it is distributed into the ring-type pouch spreads on the acupuncture point, affected part, treat ophthalmic by dermal osmosis.

Calculus Bovis of the present invention is meant the cholelithiasis of cattle, and Fel Ursi is meant the bile of Bears.

Embodiments of the invention apply to clinical trial, through male 325 people, women 278 people totally 603 routine clinical observation on the therapeutic effect, and vision 4.0-4.1 totally 135 people before the treatment; 4.2-4.5 totally 301 people; 4.6-4.9 totally 167 people; Treat check after month:

Cure (reaching more than 5.0) 312 people, healing accounts for 51.7%

Produce effects (improving more than 0.5) 251 people, produce effects accounts for 41.86%

As changeing (improving more than 0.3) 40 people, take a turn for the better and account for 6.44%

Total effective rate 100%.

Claims

1, treats bathomorphic liniment, it is characterized in that it is made of (by weight) promptly first group five groups of medicines: 50 parts of Radix Rhodiolaes, 10 parts of Fel Ursis, 10 parts of Calculus Boviss, 10 parts of Calaminas, 40 parts of Rhizoma Coptidis, 50 parts of Magnetitums, 100 parts of Borneolum Syntheticums, 50 parts of Concha Haliotidis; Second group is 50 parts of Rhizoma Atractylodis, 40 parts of the Cortexs Eucommiae, 50 parts of Fructus Rosae Laevigatae, 30 parts of Semen Ziziphi Spinosaes, 50 parts of Radix Polygalaes, 50 parts of Rhizoma Acori Gramineis, 20 parts of the Radix Paeoniae Albas, 30 parts of Radix Paeoniae Rubra; The 3rd group is 30 parts of Periostracum Cicadaes, 50 parts of Herba Schizonepetaes, 50 parts of the Rhizoma Anemarrhenaes, 50 parts of Cortex Phellodendris;

The 4th group is 20 parts in the Radix Rehmanniae, 100 parts of Herba Dendrobiis, 50 parts of Herba Ecliptaes, 50 parts in Radix Rehmanniae Preparata, 50 parts of Radix Angelicae Sinensis, 50 parts of Radix Scrophulariaes, 30 parts of Fructus Leonuris;

2, liniment as claimed in claim 1 is characterized in that Calculus Bovis is the cholelithiasis of cattle, and Fel Ursi is the bile of Bears, and Radix Rhodiolae and Rhizoma Acori Graminei are its medicinal parts.

3, treat the manufacture method of bathomorphic liniment according to claim 1, it is characterized in that: first group of medicine pulverized 100 mesh sieves with Magnetitum, Radix Rhodiolae, Rhizoma Coptidis, Calamina, Concha Haliotidis and wrapped with cloth bag, put into 5000 parts of distilled water decocting in water extractions 2 hours together with other components in the group, remove slag and filter the group pharmaceutical extraction liquid of winning; Second group of medicine three parch of low baking temperature, each 15 minutes, parch for the first time dropped into 100 parts of Mel, and parch for the second time drops into 100 parts of flours, and the input of parch for the third time rice vinegar 20 minutes is fried to the no smell of vinegar of the little Huang of epidermis, and levigation is crossed 100 mesh sieves and is got second group of drug powder; The 3rd group of medicine uses the saline solution of concentration 10% to soak 48 hours, and oven dry back levigation is crossed 100 mesh sieves and got the 3rd group of drug powder; The 4th group of medicine spills with Huang and soaked 100 hours, takes out and steams 2 hours again, and the oven dry levigation is crossed 100 mesh sieves and got the 4th group of drug powder; With 50 ℃ of water loggings bubble after 48 hours, the oven dry levigation is crossed 100 mesh sieves and is got the 5th group of drug powder behind the 5th group of medicine flush away impurity; First group of medicinal extract and second and third, four, five groups of one of drug powders are stirred, promptly make treatment myopia liniment after the drying.