CN113876692A - External use eye cream and its preparation method - Google Patents

External use eye cream and its preparation method Download PDF

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CN113876692A
CN113876692A CN202111208445.5A CN202111208445A CN113876692A CN 113876692 A CN113876692 A CN 113876692A CN 202111208445 A CN202111208445 A CN 202111208445A CN 113876692 A CN113876692 A CN 113876692A
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eye
eyes
liver
eye cream
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顾逸屏
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Jiangsu Eye Health Biotechnology Co ltd
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Jiangsu Eye Health Biotechnology Co ltd
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    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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Abstract

The invention relates to an external eye cream and a preparation method thereof, wherein the external eye cream is prepared from butterflybush flower, chrysanthemum, safflower, cassia seed, semen celosiae, puncturevine caltrop fruit, medlar, coptis chinensis, Chinese dodder seed, szechuan lovage rhizome, desertliving cistanche, divaricate saposhnikovia root, amur corktree bark, antelope horn, artificial bear gall and egg yolk. The invention adopts a new process of negative pressure extraction to extract the eyesight improving essence, the barrier-removing peptide and the kidney-tonifying enzyme, fully permeates into fundus tissues with pathological changes by opening a liver eye channel, strongly breaks through a blocked eye channel, cleans rubbish toxins in eyes, ensures sufficient nutrition supply to the eyes, promotes blood circulation of the eyes, ensures that eye cells are full, and keeps good eye circulation capacity; can improve eyesight, adjust diopter and improve microcirculation by activating collaterals and inducing resuscitation; through manual massage, the medicinal preparation permeates into each acupoint to play roles in soothing liver and relieving depression, promoting blood circulation and removing obstruction in channels, tonifying kidney and nourishing yin, supplementing optic nerve nutrition, improving microcirculation around eyes, gradually recovering vision, and achieving the purpose of conditioning and maintaining.

Description

External use eye cream and its preparation method
The technical field is as follows:
the invention relates to a preparation method of external eye cream which is prepared by taking traditional Chinese medicines as raw materials and used for conditioning myopia, amblyopia, astigmatism, strabismus and asthenopia of teenagers and conditioning senile giddiness.
Background art:
myopia, amblyopia, astigmatism, strabismus, asthenopia and senile presbyopia of teenagers are common ophthalmopathy of ophthalmology, and the incidence rate is extremely high. Particularly, the popularization and application of electronic products at present, the harm of electronic products such as computers, mobile phones and the like to eyes seriously harms the physical and mental health of people, particularly teenagers, no extremely effective method is found for treating the disease at present, physical therapies such as magnetic therapy, black material covering, red light flicker therapy, afterimage therapy and corrective therapy by wearing glasses are generally adopted, the therapies play a certain role, but cannot eradicate, treat symptoms and root causes, are easy to rebound, have long treatment course and have unsatisfactory curative effect.
The invention content is as follows:
the invention aims to provide an external eye cream for regulating myopia, amblyopia, astigmatism, strabismus, asthenopia and senile presbyopia and a preparation method thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
an external eye cream for conditioning and preventing myopia, amblyopia, astigmatism, strabismus, asthenopia and senile presbyopia, which comprises the following components in parts by weight:
Figure RE-GDA0003339396870000011
in a preferred embodiment of the present invention, the external eye cream is preferably composed of the following components in parts by weight: 40 parts of butterflybush flower, 30 parts of chrysanthemum, 30 parts of safflower, 40 parts of cassia seed, 30 parts of green boxthorn, 30 parts of caltrop, 40 parts of medlar, 40 parts of coptis chinensis, 40 parts of dodder, 40 parts of szechuan lovage rhizome, 40 parts of cistanche, 40 parts of divaricate saposhnikovia root, 30 parts of amur corktree bark, 40 parts of antelope horn, 15 parts of artificial bear gall and 3 parts of egg yolk.
The preparation method of the external eye cream comprises the following steps:
(1) taking the butterflybush flower, the chrysanthemum, the safflower, the cassia seed, the seed of Twotooth, the caltrop, the medlar, the coptis root and the south dodder seed according to the proportion
Figure RE-GDA0003339396870000021
Adding water with the amount of 8-10 times of that of the medicinal materials into the seeds, the ligusticum wallichii, the cistanche deserticola, the radix sileris and the phellodendron bark for negative pressure extraction, carrying out extraction for 3 hours for the first time, filtering and collecting an extracting solution, carrying out extraction for 2.5 hours for the second time, filtering and collecting the extracting solution, carrying out extraction for 2 hours for the third time, removing slag and filtering and collecting the extracting solution, collecting liquid medicine for the third time, decocting the liquid medicine for 3 hours by slow fire, combining filtrate and concentrating clear paste;
(2) taking antelope horn and artificial bear gall according to a proportion, crushing and mixing, and mixing according to the weight ratio of 1: 20 adding 85% edible alcohol, decocting at 60-80 deg.C for 4 hr, removing egg white from cooked egg, decocting yellow in the medicinal liquid with medium fire, promoting oil with strong fire, and pressing yolk with a spoon to obtain brown egg oil;
(3) mixing the liquid medicines in the steps (1) and (2), adding wheat germ oil, stirring uniformly to obtain an ointment, and subpackaging.
The following explains the effects of various drugs on the regulation of eye diseases such as myopia, astigmatism, strabismus, asthenopia, etc.
Flos Buddlejae has effects of clearing heat, nourishing liver, improving eyesight, eliminating nebula, preventing dacryosis, and preventing blurred vision; chrysanthemum, belonging to wind-dispelling and heat-dissipating herbs, is well-known as wind-dispelling and heat-dissipating herbs for calming liver and improving eyesight, and is used for wind-heat ophthalmopathy, conjunctival congestion and swelling pain, photophobia and lacrimation; safflower, having the functions of stimulating the menstrual flow, nourishing the blood, promoting blood circulation and removing blood stasis; semen cassiae has the effects of clearing heat, improving eyesight, moistening intestines and relaxing bowels, can be used for cataract external-obstruction, can improve eyesight, nourish liver and kidney, mainly suppress hyperactive nerves and nourish yin, is a treatment for banking up root, can clear liver, improve eyesight, calm liver, suppress yang, nourish liver and kidney, moisten intestines and relax bowels, is used for liver heat and conjunctival congestion, nebula condensation fat, photophobia and lacrimation, is used for liver yang hyperactivity, dizziness and blurred vision, is used for liver and kidney yin deficiency, blurred vision, cyanosis and night blindness; the black box has the functions of clearing liver and removing nebula due to bitter and cold-lowering and eye-clearing, is usually used for treating the nebula membrane with red eyes, heat evil and pathogenic heat, heat-clearing and wind-dispelling, calming the liver and suppressing yang hyperactivity, is applied to liver heat and red eyes, tight and small pupils, nebula generation of black eyes, pain and lacrimation, mainly treats wind heat invading eyes, white eye and red eyes, thick eye secretion and unsmooth eye secretion, is applied to liver yang hyperactivity, blood pressure increase, headache and dizziness and blurred vision; the wolfberry fruit belongs to the medicines for nourishing liver and kidney, can nourish liver and kidney, benefit vital essence and improve eyesight, and is used for liver and kidney weakness, cyanosis, night blindness, blurred vision, nebula transferring to the eyes, kidney tonifying and nebula removing for old and weak people, liver and kidney yin deficiency, nebula cataract, blurred vision, liver tonifying and tear stopping for liver deficiency lacrimation, cold lacrimation, severe wind, dim sight; the dodder has the effects of tonifying kidney and replenishing vital essence, nourishing liver and improving eyesight, tonifying spleen and checking diarrhea, and tonifying liver and kidney for liver and kidney yin deficiency, dizziness and tinnitus, soreness and weakness of waist and knees, dim eyesight and vision loss; rhizoma ligustici wallichii for promoting qi and blood circulation, treating the eye diseases caused by qi stagnation and blood stasis, the blood stasis in eyes and the retinal vessel obstruction, dispelling wind and relieving pain, treating the headache, the eye pain and the eyebrow pain caused by pathogenic factors, dispelling wind and removing dampness, treating the rheumatic headache, the body pain, the eye pain, dispelling wind and removing nebula, treating the nebula caused by wind, treating the pain, photophobia, dispelling wind and relieving itching, treating the wind-evil and the eye itching or the itching as well as the insect movement or the very difficult to endure; cistanchis herba has effects of invigorating kidney yang, replenishing essence and blood, loosening bowel to relieve constipation, invigorating kidney and tonifying yang, and can be used for treating deficiency of kidney yang, sexual impotence, cold sperm, soreness of waist and knees, slow decline of vision, dim eyesight, and black flower in front of eye; fructus tribuli, belonging to nebula-removing and obstacle-eliminating medicine, can calm the liver, relieve depression, activate blood, expel wind, improve eyesight, relieve itching, expel wind, clear heat, treat hot conjunctival congestion, pain, lacrimation, expel wind, remove nebula, treat hot nebula, photophobia, relieve wind, relieve itching, treat liver-yang hyperactivity, dizziness headache, dim food, sooth the liver, relieve pain, treat liver depression, chest and hypochondrium, pain, and swelling and pain of eyes; coptis root, rhizoma coptidis, capable of clearing heat and drying dampness, purging fire and removing toxicity, clearing heart fire and purging fire, and clearing heat and cooling blood for damp-heat accumulation and steaming, conjunctival congestion and secondary pain, nebula and cluster generation, fat coagulation, floating, crisp and tender, and tight pupil, is used for pestilence toxin, sore furuncle and carbuncle swelling, red swelling of eyes and faces or red swelling of white eye and eye, is used for heart fire upper support, large canthus benefit, pus or angular erosion of canthus or red eye or red vessel eye, and is used for blood heat bleeding, intraocular hemorrhage or traumatic hemorrhage; phellodendron bark, cortex Phellodendri, radix Angelicae sinensis, cortex Phellodendri, radix Angelicae sinensis, radix rehmanniae Preparata, radix et rhizoma Rhei, radix rehmanniae, radix et rhizoma Rhei, radix Polygalae, radix Polygalae, radix et rhizoma Rhei, radix Polygalae, radix Polygalae, radix, and radix Polygalae; radix sileris, belonging to the drugs for relieving exterior syndrome and dispelling cold, has light and floating nature, is well known to remove wind evil, can expel wind, reduce red, expel wind, relieve itching, expel wind, activate collaterals, ascend hair, remove nebula, help spleen to ascend, clear and treat wind evil, conjunctival congestion, swelling pain, photophobia, lacrimation or more gum in eyes, treat wind evil, middle collateral, ptosis, facial distortion and eye drop strabismus, is used for spleen qi not ascending and is used for frequent eye drop; antelope horn, belong to calming the liver and calming the wind medicine, it can calm the liver and calm the wind, clear liver and improve vision, dispel the blood, detoxify, calm the liver and calm the wind and use in the liver wind to disturb, green wind, blue wind, headache eye drop, the pearl is hard like wood, clear liver and remove nebula and use in the membrane of nebula of liver fire, the red eye is painful, photophobia, cool blood and detoxify, use for blood heat and graceful, the red membrane is drooped, the blood nebula wraps the eye; wheat germ oil is an excellent emollient containing various unsaturated fatty acids, such as vitamin E, and has antiaging and antioxidant effects.
The invention has the following characteristics and advantages:
1. the most advanced negative pressure extraction method is adopted for extracting medicinal materials;
2. in the formula, the butterflybush flower, the wild chrysanthemum flower and the safflower are natural wild medicinal materials from Tibet, and the three medicinal materials are extracted and evolved by advanced negative pressure to generate the eyesight improving essence which can clear liver and improve eyesight, protect eyes, moisten eye tissue cells, protect eye nerve and improve eyesight, and can be combined with hemoglobin of eyes to supplement lutein lost in the eyes, repair damaged optic nerves, prevent eyeground angiosclerosis, nourish eye tissues and improve the vitality of the optic nerves;
3. according to the prescription, the -removing peptide extracted from semen cassiae, the feather cockscomb seeds, semen cuscutae and fructus lycii through advanced negative pressure extraction can dredge aqueous humor stasis of eyes, peel and emulsify eye barriers hidden at various positions in eyes, remove the eye barriers along with tears, repair damaged optic nerves, allow crystalline lenses to become transparent and allow the eyes to see things clearly and brightly;
4. the formulation comprises 'Sha decorate ginseng' beautiful cistanche salsa, and simultaneously extracts kidney-tonifying enzyme with grassleaf sweelflag rhizome, Szechuan lovage rhizome, amur corktree bark and tribulus fruit, so that the liver and kidney stasis can be removed in a short time, the qi and blood of the liver and kidney are sufficient, the shrunken eye tissue cells are nourished, and the eye tissue function is recovered.
Description of the drawings:
fig. 1 is a process flow diagram of a method for preparing the external eye cream of the present invention.
The specific implementation mode is as follows:
the following detailed description of the preferred embodiments of the present invention, taken in conjunction with the accompanying drawings, will make the advantages and features of the invention more readily understood by those skilled in the art, and thus will more clearly and distinctly define the scope of the invention.
The first embodiment is as follows:
in the embodiment, 40 parts of butterflybush flower, 30 parts of chrysanthemum, 30 parts of safflower, 40 parts of cassia seed, 30 parts of green boxthorn, 30 parts of caltrop, 40 parts of medlar, 40 parts of coptis chinensis, 40 parts of dodder, 40 parts of ligusticum wallichii, 40 parts of cistanche, 40 parts of divaricate saposhnikovia root, 30 parts of golden cypress, 40 parts of antelope horn, 15 parts of artificial bear gall and 3 parts of egg yolk are adopted;
the manufacturing method is shown in figure 1:
(1) taking the butterflybush flower, the chrysanthemum, the safflower, the cassia seed, the seed of Twotooth, the caltrop, the medlar, the coptis root and the south dodder seed according to the proportion
Figure RE-GDA0003339396870000051
Adding water with the amount of 8-10 times of that of the medicinal materials into the seeds, the ligusticum wallichii, the cistanche deserticola, the radix sileris and the phellodendron bark for negative pressure extraction, carrying out extraction for 3 hours for the first time, filtering and collecting an extracting solution, carrying out extraction for 2.5 hours for the second time, filtering and collecting the extracting solution, carrying out extraction for 2 hours for the third time, removing slag and filtering and collecting the extracting solution, collecting liquid medicine for the third time, decocting the liquid medicine for 3 hours by slow fire, combining filtrate and concentrating clear paste;
(2) taking antelope horn and artificial bear gall according to a proportion, crushing and mixing, and mixing according to the weight ratio of 1: 20 adding 85% edible alcohol, decocting at 60-80 deg.C for 4 hr, removing egg white from cooked egg, decocting yellow in the medicinal liquid with medium fire, promoting oil with strong fire, and pressing yolk with a spoon to obtain brown egg oil;
(3) mixing the liquid medicines in the steps (1) and (2), adding wheat germ oil, stirring uniformly to obtain an ointment, and subpackaging.
Example two:
in the embodiment, 45 parts of butterflybush flower, 22 parts of chrysanthemum, 36 parts of safflower, 53 parts of cassia seed, 39 parts of green boxthorn, 25 parts of caltrop, 46 parts of medlar, 24 parts of coptis chinensis, 31 parts of dodder, 55 parts of ligusticum wallichii, 32 parts of cistanche, 49 parts of divaricate saposhnikovia root, 31 parts of golden cypress, 44 parts of antelope horn and 12 parts of artificial bear gall are adopted;
the manufacturing method is the same as the first embodiment.
Example three:
in the embodiment, 30 parts of butterflybush flower, 40 parts of chrysanthemum, 40 parts of safflower, 30 parts of cassia seed, 40 parts of green box, 20 parts of caltrop, 60 parts of medlar, 40 parts of coptis chinensis, 30 parts of dodder, 60 parts of ligusticum wallichii, 40 parts of cistanche, 30 parts of divaricate saposhnikovia root, 50 parts of golden cypress, 30 parts of antelope horn and 30 parts of artificial bear gall are adopted;
the manufacturing method is the same as the first embodiment.
The following is a clinical summary of the topical eye creams of the present invention:
the clinical application of the invention can effectively condition the vision, and the following is the summary of clinical observation.
The age of the patient is 6-20 years old, myopia, amblyopia, astigmatism, strabismus, asthenopia and ametropia.
134 eyes of the conditioning group were rubbed with eye cream for external use, and 60 eyes of the control group were not conditioned, only the eye use habit was improved, and the eye exercises were performed consistently.
The two conditioning results were as follows:
Figure RE-GDA0003339396870000061
has no adverse reaction in the using process and no toxic or side effect on human bodies.
The formula of the invention is formed by following the dialectical compatibility theory of the traditional Chinese medicine, the whole formula is reasonably compatible and complements each other, and the effects of the medicines are stronger in synergistic effect. Especially, a new process of negative pressure extraction is adopted to extract the eyesight improving essence, the barrier removing peptide and the kidney tonifying enzyme. By opening the liver-eye channel, the medicine can fully permeate into the eyeground tissue with pathological changes, strongly open the blocked eye channel, clean the intraocular waste toxin, ensure sufficient nutrition supply to the eyes, promote the blood circulation of the eyes, ensure the eyes to be full of cells, recover the normal function and maintain good eye circulation capability. It can improve eyesight, adjust diopter, and improve microcirculation by activating collaterals and inducing resuscitation. In particular, professional functional personnel specially trained are smeared on relevant acupuncture points of a patient and are massaged by manipulations, so that the medicinal preparation permeates into each acupuncture point, and the purposes of soothing liver, relieving depression, promoting blood circulation, removing obstruction in channels, tonifying kidney, nourishing yin, supplementing optic nerve nutrition, improving microcirculation around eyes, gradually recovering vision, and conditioning and maintaining are achieved.
While particular embodiments of the present invention have been described in the foregoing specification, the various illustrations do not limit the spirit of the invention, and one of ordinary skill in the art, after reading the description, can make modifications and alterations to the particular embodiments described above without departing from the spirit and scope of the invention.

Claims (3)

1. An external eye cream for conditioning and preventing myopia, amblyopia, astigmatism, strabismus, asthenopia and senile presbyopia is characterized by comprising the following components in parts by weight:
Figure RE-FDA0003339396860000011
2. the external eye ointment as claimed in claim 1, wherein the external eye cream is composed of the following components in parts by weight:
40 parts of butterflybush flower, 30 parts of chrysanthemum, 30 parts of safflower, 40 parts of cassia seed, 30 parts of green boxthorn, 30 parts of caltrop, 40 parts of medlar, 40 parts of coptis chinensis, 40 parts of dodder, 40 parts of szechuan lovage rhizome, 40 parts of cistanche, 40 parts of divaricate saposhnikovia root, 30 parts of amur corktree bark, 40 parts of antelope horn, 15 parts of artificial bear gall and 3 parts of egg yolk.
3. A method for preparing the eye cream for external use as set forth in any one of claims 1 or 2, comprising the steps of:
(1) taking the butterflybush flower, the chrysanthemum, the safflower, the cassia seed, the seed of Twotooth, the caltrop, the medlar, the coptis root and the south dodder seed according to the proportion
Figure RE-FDA0003339396860000012
Adding water with the amount of 8-10 times of that of the medicinal materials into the seeds, the ligusticum wallichii, the cistanche deserticola, the radix sileris and the phellodendron bark for negative pressure extraction, carrying out extraction for 3 hours for the first time, filtering and collecting an extracting solution, carrying out extraction for 2.5 hours for the second time, filtering and collecting the extracting solution, carrying out extraction for 2 hours for the third time, removing slag and filtering and collecting the extracting solution, collecting liquid medicine for the third time, decocting the liquid medicine for 3 hours by slow fire, combining filtrate and concentrating clear paste;
(2) taking antelope horn and artificial bear gall according to a proportion, crushing and mixing, and mixing according to the weight ratio of 1: 20 adding 85% edible alcohol, decocting at 60-80 deg.C for 4 hr, removing egg white from cooked egg, decocting yellow in the medicinal liquid with medium fire, promoting oil with strong fire, and pressing yolk with a spoon to obtain brown egg oil;
(3) mixing the liquid medicines in the steps (1) and (2), adding wheat germ oil, stirring uniformly to obtain an ointment, and subpackaging.
CN202111208445.5A 2021-10-18 2021-10-18 External use eye cream and its preparation method Pending CN113876692A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1085792A (en) * 1993-07-30 1994-04-27 高峰 Treat bathomorphic liniment and preparation method thereof
CN102631557A (en) * 2012-04-25 2012-08-15 齐春发 Traditional Chinese medicine composition for treating cataract, external oculopathy, presbyopia and myopia and preparation method thereof
CN104740334A (en) * 2013-12-30 2015-07-01 广州白云山陈李济药厂有限公司 Traditional Chinese medicinal composition for preventing and treating cataract and preparation method of traditional Chinese medicinal composition
CN107029036A (en) * 2017-04-24 2017-08-11 北京波阿斯生物科技有限公司 A kind of eye sticker formula and its patch preparation method
CN110151920A (en) * 2019-06-18 2019-08-23 江苏眼健生物科技有限公司 Treat near-sighted amblyopia astigmatism and Chinese medicine composition of visual fatigue and preparation method thereof
CN110934976A (en) * 2019-11-05 2020-03-31 张志山 Medicine for treating myopia and preparation method thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1085792A (en) * 1993-07-30 1994-04-27 高峰 Treat bathomorphic liniment and preparation method thereof
CN102631557A (en) * 2012-04-25 2012-08-15 齐春发 Traditional Chinese medicine composition for treating cataract, external oculopathy, presbyopia and myopia and preparation method thereof
CN104740334A (en) * 2013-12-30 2015-07-01 广州白云山陈李济药厂有限公司 Traditional Chinese medicinal composition for preventing and treating cataract and preparation method of traditional Chinese medicinal composition
CN107029036A (en) * 2017-04-24 2017-08-11 北京波阿斯生物科技有限公司 A kind of eye sticker formula and its patch preparation method
CN110151920A (en) * 2019-06-18 2019-08-23 江苏眼健生物科技有限公司 Treat near-sighted amblyopia astigmatism and Chinese medicine composition of visual fatigue and preparation method thereof
CN110934976A (en) * 2019-11-05 2020-03-31 张志山 Medicine for treating myopia and preparation method thereof

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