CN108578269A - Have effects that educate the composition of hair and Anti-hair loss, the preparation method of cosmetics, Essence and Essence - Google Patents
Have effects that educate the composition of hair and Anti-hair loss, the preparation method of cosmetics, Essence and Essence Download PDFInfo
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- CN108578269A CN108578269A CN201810101504.0A CN201810101504A CN108578269A CN 108578269 A CN108578269 A CN 108578269A CN 201810101504 A CN201810101504 A CN 201810101504A CN 108578269 A CN108578269 A CN 108578269A
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- hair
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
Abstract
The invention discloses the preparation methods of a kind of composition educate with hair and Anti-hair loss, cosmetics, Essence and Essence.The composition educate with hair and Anti-hair loss of the present invention includes that the raw material of following mass fraction is made：0.001 10 parts of 1 bronze medal of tripeptides, 0.01 5 parts of biotin, 0.01 10 parts of niacinamide, 0.01 20 parts of panthenol and solvent composition.The composition educate with hair and Anti-hair loss of the present invention is with promoting blood circulation, promote hair regeneration, pre-Anti-hair loss, the effects that nutrition scalp, root of hair, repairing hair follicle.Including the cosmetics for having effects that educate the composition of hair and Anti-hair loss and the Essence can equally have effects that described have effects that educate the composition of hair and Anti-hair loss.
Description
Technical field
The present invention relates to cosmetic technical fields, and in particular to a kind of to have effects that educate the composition of hair and Anti-hair loss, change
The preparation method of cosmetic, Essence and Essence.
Background technology
Hair not only plays an important role in the appearance of the mankind, while being also one of the important indicator of health.
Modern is influenced by the factors such as busy, operating pressure, environmental pollution of living, and hair easy fracture, ahead of time aging conditions occurs, sternly
Ghost image rings image appearance.The de- originator of men and women is more and more, and the trend of rejuvenation is just being presented in alopecia, and alopecia problem has become generation
The problem of criticality, prevention and treatment alopecia become the problem of cosmetics, medicine trade.
The growth of hair and fall off in periodically, under normal circumstances, each intrafollicular natural on-off cycles of hair growth follows periodicity
Rule, be divided into 3 stages：Growth period, catagen and stand-down.In general, the growth period of hair about 3 years, catagen about 3
Week, about 3 months stand-down.Under normal circumstances, in whole hairs about 85%~90% be in growth period, 10%~15% is in
Catagen and stand-down.So-called alopecia refers to there is the hair shaft of hair medulla to fall off, and replaced by fine hair on birds or animals hair, even completely bald
The case where, the reason of hair follicle does not also completely disappear, causes this phenomenon is to shorten in the growth period of hair.According to the growth of hair
Feature, can in terms of several pre-Anti-hair loss：Stand-down hair is converted as anagen hair (hair induction)；Keep growth period longer
Continue (hair growth promotion) long；Reduce stand-down hair (alopecia prevention)；Hair follicle cell Effect of promoting growth.
For the growth rhythm and process of hair, Anti-hair loss hair-growing composition can reduce alopecia and promotion in terms of several
Hair regeneration.Therefore, which kind of raw material is selected, and applies it in cosmetics and achievees the effect that educate hair and Anti-hair loss, is urgently
It solves the problems, such as.
Invention content
The purpose of the present invention is overcoming above-mentioned technical problem, provide a kind of composition educate with hair and Anti-hair loss,
The preparation method of cosmetics, Essence and Essence.
Technical scheme is as follows：
There is provided it is a kind of have effects that educate the composition of hair and Anti-hair loss, including the raw material of following mass fraction is made：
Remaining is solvent.
Preferably, the solvent includes one or both of water, yushania water.
Preferably, the biotin mass fraction is 0.01-0.05 parts preferred.
It is described the present invention also provides a kind of cosmetics including the composition educate with hair and Anti-hair loss
The composition for having effects that educate hair and Anti-hair loss accounts for the 1-85% of the cosmetics gross mass.
It is described the present invention also provides a kind of Essence including the composition educate with hair and Anti-hair loss
The composition for having effects that educate hair and Anti-hair loss accounts for the 1-85% of the Essence gross mass, and the Essence further includes following matter
Measure the component of percentage：
A phase components：Glycerine 0.1-20%
Butanediol 0.1-20%
Allantoin 0.01-10%
Acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymers 0.01-5%；
Deionized water：Surplus.
The present invention also provides a kind of preparation methods of the Essence, include the following steps：
Step S1, the deionized water of A phase components and surplus is added and is stirred under vacuum in pot, be heated to 80-85 DEG C, high speed is
Matter 2-3 minutes, insulated and stirred 20-40 minutes is to being completely dissolved；
Step S2, mixing speed is reduced to 30 revs/min, and is cooled；
Step S3, B phase components are added when temperature is down to 50 DEG C, high speed homogenization 3-8 minute is to uniformly mixed；
Step S4, when temperature is down to 38 DEG C, C phase components is added and have effects that educate the composition of hair and Anti-hair loss, mix
It closes uniform；
Step S5, it discharging and stands.
Compared with the relevant technologies, the composition educate with hair and Anti-hair loss provided by the invention, cosmetics and
Essence has the advantages that：It can prevent skin excessive damage, have anti-oxidant, improvement inflammation effect, can repair
There is stimulation hair to generate, can promote the normal operation and growth of skin and hair, be effectively improved the inflammation shape of skin for stem cell
Condition and trichomadesis is prevented, hair jag can be prevented, is damaged, increase the density of hair, improve the gloss of hair quality, it can be in skin table
Layer forms the water-retaining film of safety.
Description of the drawings
To describe the technical solutions in the embodiments of the present invention more clearly, make required in being described below to embodiment
Attached drawing is briefly described, and drawings in the following description are only some embodiments of the invention, common for this field
For technical staff, without creative efforts, other attached drawings are can also be obtained according to these attached drawings,
In：
Fig. 1 is the flow chart of the preparation method of Essence of the present invention.
Specific implementation mode
The technical scheme in the embodiments of the invention will be clearly and completely described below, it is clear that described implementation
Example is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, this field is common
All other embodiment that technical staff is obtained without making creative work belongs to the model that the present invention protects
It encloses.
Have effects that educate the composition of hair and Anti-hair loss the present invention provides a kind of, includes the raw material system of following mass fraction
At：
Remaining is solvent.
Wherein, the solvent includes one or both of water, yushania water.The yushania water refers to：Yushania
Culm cross section microstructure is porous structure, is made of numerous microcatheter fibers, and this structure is just similar " vaccum suction pipe "
Large quantity of moisture is constantly up conveyed from root, it is sugared containing indispensable silicon in a large amount of natural moisturizing factor in " suction pipe ",
Moisture can be captured, is endlessly absorbed water, safe water-retaining film can be formed in skin surface.
- 1 copper of tripeptides can be with stimulation collagen in fibroblastic synthesis, being capable of statocyte epimatrix (EMC) egg
It is white to decompose, prevent skin excessive damage；Has anti-oxidant, anti-inflammatory effect.Itself be a kind of promotion skin it is anti-ageing it is newborn, repair
The natural constituent for reducing microgroove again, improving cutis laxa, reduce pigmentation, increasing skin density thickness.Hair follicle is skin
The differentiation of the main source of skin multipotential stem cell, stem cell can potentially update skin and restore hair follicle, and -1 copper of tripeptides can
To repair stem cell, have the function of that hair is stimulated to generate.
Biotin is the confactor of many enzymes of animal body, is improving metabolism, is improving animal reproduction performance, prevention
Disease etc. plays a significant role, and is that animal body maintains one of essential vitamin of normal physiological function.It can promote
The normal operation and growth of skin and hair are effectively improved the inflammatory conditions of skin and prevent trichomadesis.Of the invention specific
In embodiment, the biotin mass fraction is 0.01-0.05 parts preferred.
Niacinamide is the main coenzyme of cellular energy metabolism, and in living cells, it can be converted to niacin, stimulation and improvement blood
The microcirculation of liquid is the cellular energy factor, for a kind of novel hair element living.
Panthenol (vitamin B5 precursor) has identical metabolic process in vivo with vitamin B5, can penetrate and be formed under hair
Elastic film stays in the interior outside of hair shaft, can prevent hair jag, is damaged, increases the density of hair, improve the gloss of hair quality.
Generally speaking, provided by the invention described to have effects that educating hair and the composition of Anti-hair loss, there is promotion blood to follow
The effects that ring, promotion hair regeneration, pre-Anti-hair loss, nutrition scalp, root of hair, repairing hair follicle.
Unless stated otherwise, the content is mass percentage；Reagent employed in embodiment, raw material are
It is commercially available.Test method without specific conditions in embodiment, usually according to normal condition or condition recommended by the manufacturer carries out.
The preparation of the composition for having effects that educate hair and Anti-hair loss, is made of following table component：
The mass percent of 1 each component of table
Effect experiment is as follows：
1. detaching people's hair follicle
It is obtained from the occipital bone head zone of 10 healthy volunteers's (18-40 Sui) and does not receive any medicine by least one moon
The ovarian follicle of object.Hair follicle is detached under stereoscopic dissecting microscope, the microdissection dermal papilla from the hair follicle individually detached.
2. in vitro people's hair follicle organ culture
In vitro people's scalp hair follicles cultured in vitro, hair follicle is separated from subcutaneous fat, and is cut from dermal papilla bottom
Lower about 2.5mm.By ovarian follicle at 37 DEG C, 5%CO2Lower incubation, containing being supplemented with L-Glutamine (2mM), insulin (10mg/
Ml 12 days) are cultivated in 48 orifice plates of the Williams'E culture mediums of hydrocortisone (40ng/ml) and antibiotic (1%), weekly
Repeat addition three times.Comparative example 1-2 in table 1 and embodiment 1-4 are added to 10% concentration in culture medium.It is aobvious using solid
Micro mirror directly measures hair follicle elongation after 6 days and 12 days in culture, the difference of calculating the 6th day and the 12nd day and the 1st day hair follicle length
It is worth (mm).240 hair follicles of (the 30 ovarian follicle/conditions) analysis from 3 different volunteers under the conditions of every group.
The in vitro people's hair follicle culture experiment of composition of table 2 comparative example 1-2 and embodiment 1-4
It is provided by the invention it can be seen from the experimental result in table 2 to have effects that educate the composition pair of hair and Anti-hair loss
The growth of hair follicle has apparent promotion and repairing effect.
It is described the present invention also provides a kind of cosmetics including the composition educate with hair and Anti-hair loss
The composition for having effects that educate hair and Anti-hair loss accounts for the 1-85% of the cosmetics gross mass.
Have effects that educate the composition of hair and Anti-hair loss described in the cosmetic applications, to relevant with the composition
Effect is not limited to educate hair and Anti-hair loss.The cosmetics are made of following table component：
The mass percent of 3 each component of table
Human efficiency's evaluation test：
Every group of 15 qualified volunteers take one's test, and volunteer uses test product, aspiration daily during test
Person areas 1.5cmx 1cm overhead 4 weeks (T4w), 8 weeks (T8w) and 12 weeks (T12w) after (T0w), product use before product use
Domain tonsures and carries out the microcosmic imaging test of hair/scalp to the region, tonsures between imaging test every two days；And make in product
It is tonsured in test zone with behind latter 2 weeks, 6 weeks and 10 weeks, to maintain hair lengths to be identified convenient for test zone.
4 weeks (T4w), 8 weeks (T8w) and 12 weeks (T12w) carries out hair/head after (T0w), product use before product use
The microcosmic imaging test of skin, hair gross density and growth period hair ratio data the results are shown in Table 4 and table 5.
Table 4
Table 5
By upper table 4 and the experimental data of table 5 as it can be seen that including the change of the composition educate with hair and Anti-hair loss
Cosmetic is significantly improved the growth tool of hair, and using the cosmetics, hair gross density and growth period hair ratio obtain
It dramatically increases.
It is described the present invention also provides a kind of Essence including the composition educate with hair and Anti-hair loss
The composition for having effects that educate hair and Anti-hair loss accounts for the 1-85% of the Essence gross mass, and the Essence further includes following matter
Measure the component of percentage：
A phase components：Glycerine 0.1-20%
Butanediol 0.1-20%
Allantoin 0.01-10%
Acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymers 0.01-5%；
Deionized water：Surplus.
The present invention also provides a kind of preparation methods of the Essence, include the following steps：
Step S1, the deionized water of A phase components and surplus is added and is stirred under vacuum in pot, be heated to 80-85 DEG C, high speed is
Matter 2-3 minutes, insulated and stirred 20-40 minutes is to being completely dissolved；
Step S2, mixing speed is reduced to 30 revs/min, and is cooled；
Step S3, B phase components are added when temperature is down to 50 DEG C, high speed homogenization 3-8 minute is to uniformly mixed；
Step S4, when temperature is down to 38 DEG C, C phase components is added and have effects that educate the composition of hair and Anti-hair loss, mix
It closes uniform；
Step S5, it discharging and stands.
After step s 5, test to the Essence formed after standing, after the assay was approved, it is filling, packaging, coding with
And storage.
The Essence belongs to one kind of cosmetics, educates hair and Anti-hair loss since the Essence equally has comprising described in
The composition of effect, similarly, the Essence, which ought to have, to promote blood circulation, promotes hair regeneration, pre-Anti-hair loss, nutrition head
The effects that skin, root of hair, repairing hair follicle.
Compared with the relevant technologies, the composition educate with hair and Anti-hair loss provided by the invention, cosmetics and
Essence has the advantages that：It can prevent skin excessive damage, have anti-oxidant, improvement inflammation effect, can repair
There is stimulation hair to generate, can promote the normal operation and growth of skin and hair, be effectively improved the inflammation shape of skin for stem cell
Condition and trichomadesis is prevented, hair jag can be prevented, is damaged, increase the density of hair, improve the gloss of hair quality, it can be in skin table
Layer forms the water-retaining film of safety.
Example the above is only the implementation of the present invention is not intended to limit the scope of the invention, every to utilize this hair
Equivalent structure or equivalent flow shift made by bright specification and accompanying drawing content is applied directly or indirectly in other relevant skills
Art field, is included within the scope of the present invention.
Claims (6)
1. a kind of have effects that educate the composition of hair and Anti-hair loss, which is characterized in that the raw material including following mass fraction is made：
2. according to claim 1 have effects that educate the composition of hair and Anti-hair loss, which is characterized in that the solvent includes
One or both of water, yushania water.
3. according to claim 1 have effects that educate the composition of hair and Anti-hair loss, which is characterized in that the biology quality
It is 0.01-0.05 parts preferred to measure number.
4. a kind of includes to have effects that educate the cosmetics of the composition of hair and Anti-hair loss as described in claim 1, feature exists
In the composition educate with hair and Anti-hair loss accounts for the 1-85% of the cosmetics gross mass.
5. a kind of includes to have effects that educate the Essence of the composition of hair and Anti-hair loss as described in claim 1, feature exists
In the composition educate with hair and Anti-hair loss accounts for the 1-85% of the Essence gross mass, and the Essence also wraps
Include the component of following mass percent：
6. a kind of preparation method of Essence as claimed in claim 5, which is characterized in that include the following steps：
Step S1, the deionized water of A phase components and surplus is added and is stirred under vacuum in pot, be heated to 80-85 DEG C, high speed homogenization 2-
3 minutes, insulated and stirred 20-40 minutes was to being completely dissolved；
Step S2, mixing speed is reduced to 30 revs/min, and is cooled；
Step S3, B phase components are added when temperature is down to 50 DEG C, high speed homogenization 3-8 minute is to uniformly mixed；
Step S4, when temperature is down to 38 DEG C, C phase components is added and have effects that educate the composition of hair and Anti-hair loss, mixing is equal
It is even；
Step S5, it discharging and stands.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810101504.0A CN108578269A (en) | 2018-02-01 | 2018-02-01 | Have effects that educate the composition of hair and Anti-hair loss, the preparation method of cosmetics, Essence and Essence |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810101504.0A CN108578269A (en) | 2018-02-01 | 2018-02-01 | Have effects that educate the composition of hair and Anti-hair loss, the preparation method of cosmetics, Essence and Essence |
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| CN108578269A true CN108578269A (en) | 2018-09-28 |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110840802A (en) * | 2019-11-26 | 2020-02-28 | 孙畅 | Hair loss preventing and growing agent |
| CN110882173A (en) * | 2019-12-05 | 2020-03-17 | 西北农林科技大学 | Formula of external daily chemical for preventing and treating alopecia by targeting hair follicle stem cells |
| CN111110618A (en) * | 2020-02-11 | 2020-05-08 | 豌豆之本(北京)科技有限公司 | A composition for promoting hair growth |
| CN111297752A (en) * | 2019-12-25 | 2020-06-19 | 夏文杰 | Microbial enzyme type anti-hair loss and hair growth liquid and preparation method thereof |
| CN113633585A (en) * | 2020-04-27 | 2021-11-12 | 美慕(北京)科技有限公司 | External hair care composition and preparation with effects of preventing alopecia, growing hair and blackening hair and preparation method thereof |
| CN114917167A (en) * | 2022-04-29 | 2022-08-19 | 云南群优生物科技有限公司 | After-sun repairing conditioning cream containing bamboo leaf extract and bamboo water and production method thereof |
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| CN107157804A (en) * | 2017-07-19 | 2017-09-15 | 广东德丝肤生物科技有限公司 | A kind of nutrition scalp hair follicles hair tonic elite and preparation method thereof |
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| CN102188690A (en) * | 2011-04-27 | 2011-09-21 | 林秀生 | Hair growth lotion and preparation method thereof |
| CN104940903A (en) * | 2015-07-13 | 2015-09-30 | 董耀蔚 | Combination formula for promoting hair to grow rapidly and preparation method of combination formula |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110840802A (en) * | 2019-11-26 | 2020-02-28 | 孙畅 | Hair loss preventing and growing agent |
| CN110882173A (en) * | 2019-12-05 | 2020-03-17 | 西北农林科技大学 | Formula of external daily chemical for preventing and treating alopecia by targeting hair follicle stem cells |
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| CN111297752A (en) * | 2019-12-25 | 2020-06-19 | 夏文杰 | Microbial enzyme type anti-hair loss and hair growth liquid and preparation method thereof |
| CN111110618A (en) * | 2020-02-11 | 2020-05-08 | 豌豆之本(北京)科技有限公司 | A composition for promoting hair growth |
| CN111110618B (en) * | 2020-02-11 | 2022-09-27 | 张运适 | A composition for promoting hair growth |
| CN113633585A (en) * | 2020-04-27 | 2021-11-12 | 美慕(北京)科技有限公司 | External hair care composition and preparation with effects of preventing alopecia, growing hair and blackening hair and preparation method thereof |
| CN113633585B (en) * | 2020-04-27 | 2024-01-30 | 美慕(北京)科技有限公司 | External hair care composition and preparation with effects of preventing alopecia, promoting hair growth and blackening hair and preparation method thereof |
| CN114917167A (en) * | 2022-04-29 | 2022-08-19 | 云南群优生物科技有限公司 | After-sun repairing conditioning cream containing bamboo leaf extract and bamboo water and production method thereof |
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Application publication date: 20180928 |
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